SIMILAR PATTERNS OF AMINO ACIDS FOR 3CE6_A_ADNA500_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ddk | IMP-1 METALLOBETA-LACTAMASE (Pseudomonasaeruginosa) |
PF00753(Lactamase_B) | 4 | GLN A 212THR A 209THR A 140HIS A 77 | NoneNoneNone ZN A 500 (-3.4A) | 1.14A | 3ce6A-1ddkA:2.6 | 3ce6A-1ddkA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e9y | UREASE SUBUNIT BETA (Helicobacterpylori) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 4 | GLN B 210THR B 173THR B 492LEU B 507 | None | 1.35A | 3ce6A-1e9yB:undetectable | 3ce6A-1e9yB:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gnx | BETA-GLUCOSIDASE (Streptomycessp.) |
PF00232(Glyco_hydro_1) | 4 | THR A 382THR A 175HIS A 213LEU A 301 | None | 1.36A | 3ce6A-1gnxA:undetectable | 3ce6A-1gnxA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iie | PROTEIN (HLA-DRANTIGENS ASSOCIATEDINVARIANT CHAIN) (Homo sapiens) |
PF08831(MHCassoc_trimer) | 4 | GLN A 131THR A 156HIS A 152LEU A 142 | None | 1.23A | 3ce6A-1iieA:undetectable | 3ce6A-1iieA:10.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kbl | PYRUVATE PHOSPHATEDIKINASE ([Clostridium]symbiosum) |
PF00391(PEP-utilizers)PF01326(PPDK_N)PF02896(PEP-utilizers_C) | 4 | GLN A 293THR A 292THR A 453LEU A 396 | None | 1.34A | 3ce6A-1kblA:2.3 | 3ce6A-1kblA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pem | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 2ALPHA CHAIN (Salmonellaenterica) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF08343(RNR_N) | 4 | GLN A 158THR A 161THR A 110LEU A 103 | None | 1.23A | 3ce6A-1pemA:undetectable | 3ce6A-1pemA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q2e | EXOCELLOBIOHYDROLASEI (Trichodermareesei) |
PF00840(Glyco_hydro_7) | 4 | GLN A 293THR A 292THR A 356LEU A 349 | None | 1.33A | 3ce6A-1q2eA:undetectable | 3ce6A-1q2eA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ujj | ADP-RIBOSYLATIONFACTOR BINDINGPROTEIN GGA1 (Homo sapiens) |
PF00790(VHS) | 4 | GLN A 36THR A 9THR A 18LEU A 51 | None | 1.23A | 3ce6A-1ujjA:undetectable | 3ce6A-1ujjA:15.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uwi | BETA-GALACTOSIDASE (Sulfolobussolfataricus) |
PF00232(Glyco_hydro_1) | 4 | THR A 386THR A 203HIS A 243LEU A 314 | None | 1.33A | 3ce6A-1uwiA:undetectable | 3ce6A-1uwiA:23.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wvi | PUTATIVEPHOSPHATASESINVOLVED INN-ACETYL-GLUCOSAMINECATABOLISM (Streptococcusmutans) |
PF13242(Hydrolase_like)PF13344(Hydrolase_6) | 4 | GLN A1053THR A1064THR A1042LEU A1074 | None | 1.29A | 3ce6A-1wviA:4.1 | 3ce6A-1wviA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a81 | CARB (Pectobacteriumcarotovorum) |
PF00378(ECH_1) | 4 | GLN A 220THR A 221THR A 148LEU A 91 | None | 1.12A | 3ce6A-2a81A:undetectable | 3ce6A-2a81A:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ahw | PUTATIVE ENZYME YDIF (Escherichiacoli) |
PF01144(CoA_trans) | 4 | GLN A 362THR A 334THR A 399LEU A 376 | NoneNoneNoneCOA A2600 (-4.9A) | 1.36A | 3ce6A-2ahwA:undetectable | 3ce6A-2ahwA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cb0 | GLUCOSAMINE-FRUCTOSE-6-PHOSPHATEAMINOTRANSFERASE (Pyrococcusfuriosus) |
PF01380(SIS) | 4 | THR A 290THR A 222HIS A 250LEU A 266 | None | 1.15A | 3ce6A-2cb0A:3.5 | 3ce6A-2cb0A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cvt | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASELARGE CHAIN 1 (Saccharomycescerevisiae) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF03477(ATP-cone) | 4 | THR A 608THR A 204HIS A 200LEU A 481 | None | 1.16A | 3ce6A-2cvtA:undetectable | 3ce6A-2cvtA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fwm | 2,3-DIHYDRO-2,3-DIHYDROXYBENZOATEDEHYDROGENASE (Escherichiacoli) |
PF13561(adh_short_C2) | 4 | GLN X 113THR X 114THR X 128LEU X 154 | None | 1.37A | 3ce6A-2fwmX:7.9 | 3ce6A-2fwmX:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hpw | GREEN FLUORESCENTPROTEIN (Clytia gregaria) |
PF01353(GFP) | 4 | GLN A 89THR A 88HIS A 200LEU A 202 | None | 1.10A | 3ce6A-2hpwA:undetectable | 3ce6A-2hpwA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nvv | ACETYL-COAHYDROLASE/TRANSFERASE FAMILY PROTEIN (Porphyromonasgingivalis) |
PF02550(AcetylCoA_hydro)PF13336(AcetylCoA_hyd_C) | 4 | GLN A 333THR A 107THR A 383HIS A 414 | GLN A 333 ( 0.6A)THR A 107 ( 0.8A)THR A 383 ( 0.8A)HIS A 414 ( 1.0A) | 1.10A | 3ce6A-2nvvA:2.6 | 3ce6A-2nvvA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o26 | MAST/STEM CELLGROWTH FACTORRECEPTOR (Mus musculus) |
no annotation | 4 | GLN X 275THR X 277THR X 306HIS X 222 | None | 1.30A | 3ce6A-2o26X:undetectable | 3ce6A-2o26X:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o8e | DNA MISMATCH REPAIRPROTEIN MSH6 (Homo sapiens) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05190(MutS_IV)PF05192(MutS_III) | 4 | THR B 750THR B1142HIS B1096LEU B1149 | None | 1.33A | 3ce6A-2o8eB:undetectable | 3ce6A-2o8eB:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q07 | UNCHARACTERIZEDPROTEIN AF0587 (Archaeoglobusfulgidus) |
PF01472(PUA) | 4 | THR A 350THR A 267HIS A 278LEU A 281 | None | 1.33A | 3ce6A-2q07A:2.1 | 3ce6A-2q07A:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qlu | ACTIVIN RECEPTORTYPE IIB (Homo sapiens) |
PF00069(Pkinase) | 4 | GLN A 246THR A 265HIS A 319LEU A 301 | NoneADE A 488 (-4.3A)NoneNone | 1.33A | 3ce6A-2qluA:undetectable | 3ce6A-2qluA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qzu | PUTATIVE SULFATASEYIDJ (Bacteroidesfragilis) |
PF00884(Sulfatase) | 4 | GLN A 380THR A 378HIS A 164LEU A 109 | None | 1.09A | 3ce6A-2qzuA:undetectable | 3ce6A-2qzuA:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w4o | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE TYPE IV (Homo sapiens) |
PF00069(Pkinase) | 4 | GLN A 147THR A 291HIS A 156LEU A 155 | None | 1.33A | 3ce6A-2w4oA:undetectable | 3ce6A-2w4oA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w55 | XANTHINEDEHYDROGENASE (Rhodobactercapsulatus) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 4 | GLN B 232THR B 516HIS B 483LEU B 492 | HPA B1780 ( 3.1A)NoneNoneXAX B1778 (-3.9A) | 1.24A | 3ce6A-2w55B:undetectable | 3ce6A-2w55B:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xk9 | CHECKPOINT KINASE 2 (Homo sapiens) |
PF00069(Pkinase) | 4 | GLN A 330THR A 477HIS A 339LEU A 338 | None | 1.26A | 3ce6A-2xk9A:undetectable | 3ce6A-2xk9A:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yia | RNA-DIRECTED RNAPOLYMERASE (Infectiouspancreaticnecrosis virus) |
PF04197(Birna_RdRp) | 4 | THR A 733THR A 411HIS A 414LEU A 482 | None | 1.33A | 3ce6A-2yiaA:undetectable | 3ce6A-2yiaA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bqy | PUTATIVE TETR FAMILYTRANSCRIPTIONALREGULATOR (Streptomycescoelicolor) |
PF00440(TetR_N)PF02909(TetR_C) | 4 | GLN A 60THR A 114HIS A 104LEU A 28 | None | 1.34A | 3ce6A-3bqyA:undetectable | 3ce6A-3bqyA:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3brz | TODX (Pseudomonasputida) |
PF03349(Toluene_X) | 4 | THR A 1THR A 55HIS A 420LEU A 374 | None | 1.36A | 3ce6A-3brzA:undetectable | 3ce6A-3brzA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dpr | PROTEIN VP2 (Rhinovirus A) |
PF00073(Rhv) | 4 | THR B 70THR B 233HIS B 118LEU B 194 | None | 1.37A | 3ce6A-3dprB:undetectable | 3ce6A-3dprB:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eeg | 2-ISOPROPYLMALATESYNTHASE (Cytophagahutchinsonii) |
PF00682(HMGL-like) | 4 | THR A 211THR A 259HIS A 263LEU A 266 | None | 1.05A | 3ce6A-3eegA:undetectable | 3ce6A-3eegA:22.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3g1u | ADENOSYLHOMOCYSTEINASE (Leishmaniamajor) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 56THR A 57THR A 156HIS A 300LEU A 343 | ADN A 438 (-3.8A)ADN A 438 (-4.6A)NAD A 439 ( 3.0A)ADN A 438 ( 4.0A)NAD A 439 ( 4.0A) | 0.19A | 3ce6A-3g1uA:55.4 | 3ce6A-3g1uA:54.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3glq | ADENOSYLHOMOCYSTEINASE (Burkholderiapseudomallei) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 66THR A 67THR A 200HIS A 344LEU A 385 | RAB A 602 (-3.9A)RAB A 602 (-4.5A)NAD A 601 ( 2.9A)RAB A 602 ( 3.5A)NAD A 601 ( 4.1A) | 0.19A | 3ce6A-3glqA:59.0 | 3ce6A-3glqA:57.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3h9u | ADENOSYLHOMOCYSTEINASE (Trypanosomabrucei) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 56THR A 57THR A 156HIS A 300LEU A 343 | ADN A 439 (-3.6A)ADN A 439 (-4.7A)NAD A 438 (-3.8A)NoneNAD A 438 (-4.0A) | 0.54A | 3ce6A-3h9uA:55.8 | 3ce6A-3h9uA:56.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i45 | TWIN-ARGININETRANSLOCATIONPATHWAY SIGNALPROTEIN (Rhodospirillumrubrum) |
PF13458(Peripla_BP_6) | 4 | GLN A 335THR A 337THR A 294LEU A 287 | None | 1.31A | 3ce6A-3i45A:5.1 | 3ce6A-3i45A:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i4x | TRYPTOPHANDIMETHYLALLYLTRANSFERASE (Aspergillusfumigatus) |
PF11991(Trp_DMAT) | 4 | GLN A 343THR A 348HIS A 396LEU A 360 | DST A 460 (-3.1A)NoneNoneNone | 1.23A | 3ce6A-3i4xA:undetectable | 3ce6A-3i4xA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ip1 | ALCOHOLDEHYDROGENASE,ZINC-CONTAINING (Thermotogamaritima) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLN A 74THR A 75THR A 87LEU A 93 | None | 1.31A | 3ce6A-3ip1A:5.8 | 3ce6A-3ip1A:23.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jbh | MYOSIN 2 HEAVY CHAINSTRIATED MUSCLE (Aphonopelma) |
PF00063(Myosin_head)PF01576(Myosin_tail_1)PF02736(Myosin_N) | 4 | GLN A 219THR A 220THR A 446LEU A 255 | None | 1.29A | 3ce6A-3jbhA:undetectable | 3ce6A-3jbhA:12.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lhh | CBS DOMAIN PROTEIN (Shewanellaoneidensis) |
PF00571(CBS) | 4 | GLN A 154THR A 133HIS A 129LEU A 126 | None | 1.36A | 3ce6A-3lhhA:undetectable | 3ce6A-3lhhA:15.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lma | STAGE V SPORULATIONPROTEIN AD (SPOVAD) (Bacilluslicheniformis) |
PF07451(SpoVAD) | 4 | GLN A 215THR A 186THR A 307LEU A 243 | None | 1.34A | 3ce6A-3lmaA:undetectable | 3ce6A-3lmaA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mr1 | METHIONINEAMINOPEPTIDASE (Rickettsiaprowazekii) |
PF00557(Peptidase_M24) | 4 | THR A 28THR A 106HIS A 234LEU A 248 | None | 1.19A | 3ce6A-3mr1A:undetectable | 3ce6A-3mr1A:20.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3n58 | ADENOSYLHOMOCYSTEINASE (Brucellaabortus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 59THR A 60THR A 193HIS A 337LEU A 378 | K A 2 ( 3.3A)ADN A 500 (-4.6A)NAD A 550 ( 3.0A)ADN A 500 ( 3.6A)NAD A 550 (-4.3A) | 0.23A | 3ce6A-3n58A:59.0 | 3ce6A-3n58A:60.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n5b | ASR0485 PROTEIN (Nostoc sp. PCC7120) |
PF12058(DUF3539) | 4 | GLN B 37THR B 14HIS B 12LEU B 18 | None | 1.34A | 3ce6A-3n5bB:undetectable | 3ce6A-3n5bB:11.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o9p | PERIPLASMIC MUREINPEPTIDE-BINDINGPROTEIN (Escherichiacoli) |
PF00496(SBP_bac_5) | 4 | THR A 316THR A 429HIS A 432LEU A 115 | None | 1.32A | 3ce6A-3o9pA:undetectable | 3ce6A-3o9pA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oaa | ATP SYNTHASE SUBUNITBETA (Escherichiacoli) |
PF00006(ATP-synt_ab)PF02874(ATP-synt_ab_N) | 4 | GLN D 268THR D 270HIS D 110LEU D 221 | None | 1.33A | 3ce6A-3oaaD:undetectable | 3ce6A-3oaaD:23.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3one | ADENOSYLHOMOCYSTEINASE (Lupinus luteus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 66THR A 67THR A 206HIS A 350LEU A 395 | ADE A 506 (-3.8A)ADE A 506 (-4.5A)NAD A 501 (-2.8A)NoneNAD A 501 (-4.2A) | 0.42A | 3ce6A-3oneA:58.6 | 3ce6A-3oneA:59.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pqy | BETA CHAIN OF THE6218-TCR (Homo sapiens;Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | GLN E 242THR E 241THR E 121LEU E 126 | None | 1.33A | 3ce6A-3pqyE:undetectable | 3ce6A-3pqyE:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qgk | UREASE SUBUNIT BETA2 (Helicobactermustelae) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 4 | GLN C 209THR C 172THR C 491LEU C 506 | None | 1.34A | 3ce6A-3qgkC:undetectable | 3ce6A-3qgkC:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qr5 | CARDIAC CA2+ RELEASECHANNEL (Mus musculus) |
PF08709(Ins145_P3_rec) | 4 | GLN A 33THR A 27THR A 210HIS A 193 | None | 1.10A | 3ce6A-3qr5A:undetectable | 3ce6A-3qr5A:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rag | UNCHARACTERIZEDPROTEIN (Alicyclobacillusacidocaldarius) |
PF00092(VWA) | 4 | THR A 84THR A 6HIS A 133LEU A 222 | None | 1.12A | 3ce6A-3ragA:3.3 | 3ce6A-3ragA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3srz | TOXIN A (Clostridioidesdifficile) |
PF12918(TcdB_N)PF12919(TcdA_TcdB) | 4 | GLN A 256THR A 427HIS A 431LEU A 434 | None | 1.19A | 3ce6A-3srzA:undetectable | 3ce6A-3srzA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ty7 | PUTATIVE ALDEHYDEDEHYDROGENASESAV2122 (Staphylococcusaureus) |
PF00171(Aldedh) | 4 | THR A 222THR A 150HIS A 103LEU A 92 | None | 1.18A | 3ce6A-3ty7A:4.0 | 3ce6A-3ty7A:24.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vbe | BETA-CYANOALNINESYNTHASE (Glycine max) |
PF00291(PALP) | 4 | GLN A 331THR A 74THR A 342HIS A 344 | None | 1.37A | 3ce6A-3vbeA:5.2 | 3ce6A-3vbeA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9u | PUTATIVE LIPASE (Proteusmirabilis) |
PF00561(Abhydrolase_1) | 4 | THR A 100THR A 3HIS A 37LEU A 32 | None | 1.29A | 3ce6A-3w9uA:undetectable | 3ce6A-3w9uA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c3h | DNA-DIRECTED RNAPOLYMERASE I SUBUNITRPA190 (Saccharomycescerevisiae) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 4 | THR A 594THR A 653HIS A 603LEU A 616 | None | 1.26A | 3ce6A-4c3hA:undetectable | 3ce6A-4c3hA:15.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c9m | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 4 | GLN A 49THR A 52THR A 58LEU A 33 | None | 1.37A | 3ce6A-4c9mA:undetectable | 3ce6A-4c9mA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cnk | L-AMINO ACID OXIDASE (Streptococcuscristatus) |
PF03486(HI0933_like) | 4 | GLN A 156THR A 6THR A 348HIS A 389 | None | 1.17A | 3ce6A-4cnkA:undetectable | 3ce6A-4cnkA:23.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ha4 | BETA-GALACTOSIDASE (Acidilobussaccharovorans) |
PF00232(Glyco_hydro_1) | 4 | THR A 384THR A 205HIS A 245LEU A 312 | None | 1.38A | 3ce6A-4ha4A:undetectable | 3ce6A-4ha4A:20.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4lvc | S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE(SAHASE) (Bradyrhizobiumelkanii) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 62THR A 63THR A 198HIS A 342LEU A 383 | NH4 A 502 ( 3.1A)ADN A 501 (-4.5A)NAD A 503 ( 2.9A)ADN A 501 ( 3.7A)NAD A 503 ( 3.9A) | 0.59A | 3ce6A-4lvcA:61.1 | 3ce6A-4lvcA:58.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n6k | TRAP DICARBOXYLATETRANSPORTER-DCTPSUBUNIT (Desulfovibriosalexigens) |
PF03480(DctP) | 4 | THR A 229THR A 235HIS A 237LEU A 185 | None | 1.04A | 3ce6A-4n6kA:undetectable | 3ce6A-4n6kA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nq1 | 4-HYDROXY-TETRAHYDRODIPICOLINATESYNTHASE (Legionellapneumophila) |
PF00701(DHDPS) | 4 | GLN A 111THR A 110THR A 81HIS A 120 | NoneNoneMRD A 301 ( 4.2A)MRD A 301 ( 4.8A) | 1.27A | 3ce6A-4nq1A:undetectable | 3ce6A-4nq1A:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pcb | TRWC (Escherichiacoli) |
PF08751(TrwC) | 4 | GLN A 126THR A 189HIS A 4LEU A 84 | None | 1.37A | 3ce6A-4pcbA:undetectable | 3ce6A-4pcbA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rh7 | GREEN FLUORESCENTPROTEIN/CYTOPLASMICDYNEIN 2 HEAVY CHAIN1 (Homo sapiens;syntheticconstruct) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 4 | GLN A2380THR A2383THR A2418HIS A2097 | None MG A4404 ( 4.6A)NoneNone | 1.35A | 3ce6A-4rh7A:undetectable | 3ce6A-4rh7A:9.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rk2 | PUTATIVE SUGAR ABCTRANSPORTER,SUBSTRATE-BINDINGPROTEIN (Rhizobium etli) |
PF01547(SBP_bac_1) | 4 | GLN A 274THR A 273HIS A 197LEU A 195 | None | 1.15A | 3ce6A-4rk2A:undetectable | 3ce6A-4rk2A:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ruw | ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE (Beutenbergiacavernae) |
PF03372(Exo_endo_phos) | 4 | GLN A 213THR A 180HIS A 194LEU A 229 | None | 1.36A | 3ce6A-4ruwA:undetectable | 3ce6A-4ruwA:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tvm | CITRATE SYNTHASE (Mycobacteriumtuberculosis) |
PF00285(Citrate_synt) | 4 | GLN A 111THR A 195THR A 204LEU A 389 | None | 1.38A | 3ce6A-4tvmA:undetectable | 3ce6A-4tvmA:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ubq | BETA-LACTAMASE (Acinetobacterbaumannii) |
no annotation | 4 | GLN A 213THR A 210THR A 141HIS A 78 | NoneNoneNone ZN A 301 (-3.4A) | 1.22A | 3ce6A-4ubqA:2.8 | 3ce6A-4ubqA:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homo sapiens) |
PF00069(Pkinase) | 4 | THR A 224THR A 283HIS A 147LEU A 146 | None | 1.17A | 3ce6A-4usfA:undetectable | 3ce6A-4usfA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wct | FRUCTOSYLAMINE:OXYGENOXIDOREDUCTASE (Aspergillusfumigatus) |
PF01266(DAO) | 4 | GLN A 93THR A 88HIS A 27LEU A 26 | None | 1.28A | 3ce6A-4wctA:undetectable | 3ce6A-4wctA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wss | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | GLN A 15THR A 14HIS A 439LEU A 436 | None | 1.12A | 3ce6A-4wssA:undetectable | 3ce6A-4wssA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xgi | GLUTAMATEDEHYDROGENASE (Burkholderiathailandensis) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 4 | GLN A 259THR A 283HIS A 279LEU A 276 | NAD A 500 ( 4.9A)NoneNoneNone | 1.30A | 3ce6A-4xgiA:undetectable | 3ce6A-4xgiA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yff | SERINE/THREONINE-PROTEIN KINASE TNNI3K (Homo sapiens) |
PF07714(Pkinase_Tyr) | 4 | GLN A 523THR A 539HIS A 586LEU A 577 | None4CV A 801 (-2.8A)NoneNone | 1.24A | 3ce6A-4yffA:undetectable | 3ce6A-4yffA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a8r | METHYL-COENZYME MREDUCTASE II,SUBUNIT BETA (Methanothermobactermarburgensis) |
PF02240(MCR_gamma) | 4 | THR C 119THR C 218HIS C 21LEU C 145 | None | 1.32A | 3ce6A-5a8rC:undetectable | 3ce6A-5a8rC:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b3r | IMP-18 (Pseudomonasaeruginosa) |
no annotation | 4 | GLN A 230THR A 227THR A 158HIS A 95 | NoneNoneNone ZN A2001 ( 3.4A) | 1.22A | 3ce6A-5b3rA:2.9 | 3ce6A-5b3rA:18.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d01 | N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATESYNTHASE (Bacillussubtilis) |
PF00534(Glycos_transf_1)PF13439(Glyco_transf_4) | 4 | GLN A 368THR A 119HIS A 94LEU A 24 | None | 1.34A | 3ce6A-5d01A:4.3 | 3ce6A-5d01A:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d8g | TRYPTOPHANASE (Escherichiacoli) |
PF01212(Beta_elim_lyase) | 4 | GLN A 140THR A 138HIS A 463LEU A 400 | NoneNoneNoneEPE A1003 (-4.3A) | 1.19A | 3ce6A-5d8gA:undetectable | 3ce6A-5d8gA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5du3 | PLASMA PROTEASE C1INHIBITOR (Homo sapiens) |
PF00079(Serpin) | 4 | GLN A 201THR A 157HIS A 185LEU A 221 | None | 1.27A | 3ce6A-5du3A:undetectable | 3ce6A-5du3A:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fd2 | SERINE/THREONINE-PROTEIN KINASE B-RAF (Homo sapiens) |
PF07714(Pkinase_Tyr) | 4 | GLN A 530THR A 529HIS A 574LEU A 567 | None5XJ A 801 (-3.4A)NoneNone | 1.37A | 3ce6A-5fd2A:undetectable | 3ce6A-5fd2A:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fse | UREASE SUBUNIT ALPHA (Sporosarcinapasteurii) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 4 | GLN C 211THR C 174THR C 493LEU C 508 | None | 1.35A | 3ce6A-5fseC:3.3 | 3ce6A-5fseC:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fug | HISTONE H2A.ZVACUOLAR PROTEINSORTING-ASSOCIATEDPROTEIN 72 HOMOLOG (Homo sapiens) |
PF00125(Histone)PF05764(YL1)PF16211(Histone_H2A_C) | 4 | GLN C 31THR A 82HIS A 85LEU A 88 | None | 1.37A | 3ce6A-5fugC:undetectable | 3ce6A-5fugC:11.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g37 | 41.9 KDAINSECTICIDAL TOXIN (Lysinibacillussphaericus) |
PF05431(Toxin_10) | 4 | GLN A 220THR A 219THR A 191LEU A 266 | None | 1.35A | 3ce6A-5g37A:undetectable | 3ce6A-5g37A:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gza | PROTEIN O-MANNOSEKINASE (Danio rerio) |
PF07714(Pkinase_Tyr) | 4 | GLN A 212THR A 209THR A 277LEU A 246 | MG A 403 (-2.6A)NoneNoneNone | 1.36A | 3ce6A-5gzaA:undetectable | 3ce6A-5gzaA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hes | MITOGEN-ACTIVATEDPROTEIN KINASEKINASE KINASE MLT (Homo sapiens) |
PF07714(Pkinase_Tyr) | 4 | GLN A 67THR A 82HIS A 131LEU A 121 | None032 A 401 (-3.7A)NoneNone | 1.12A | 3ce6A-5hesA:undetectable | 3ce6A-5hesA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i51 | TRANSKETOLASE (Scheffersomycesstipitis) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | THR A 483THR A 477HIS A 478LEU A 471 | None | 1.31A | 3ce6A-5i51A:undetectable | 3ce6A-5i51A:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lde | IMMUNOGLOBULING-BINDING PROTEING,VIRAL FLICEPROTEIN (Humangammaherpesvirus8;Streptococcussp. 'group G') |
PF01335(DED)PF01378(IgG_binding_B) | 4 | THR A 152THR A 187HIS A 183LEU A 180 | None | 1.38A | 3ce6A-5ldeA:undetectable | 3ce6A-5ldeA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lsm | FMN-DEPENDENTNITRONATEMONOOXYGENASE (Shewanellaoneidensis) |
PF03060(NMO) | 4 | GLN A 326THR A 156HIS A 185LEU A 191 | None | 1.15A | 3ce6A-5lsmA:undetectable | 3ce6A-5lsmA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nci | LEUCINE HYDROXYLASE (Streptomycesmuensis) |
PF05721(PhyH) | 4 | GLN A 111THR A 227HIS A 92LEU A 122 | None | 1.26A | 3ce6A-5nciA:undetectable | 3ce6A-5nciA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nd1 | CAPSID PROTEIN (Rosellinianecatrixquadrivirus 1) |
no annotation | 4 | GLN A 467THR A 468THR A 520LEU A 608 | None | 0.95A | 3ce6A-5nd1A:undetectable | 3ce6A-5nd1A:10.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u6s | UDP-GLYCOSYLTRANSFERASE 74F2 (Arabidopsisthaliana) |
PF00201(UDPGT) | 4 | GLN A 24THR A 20THR A 348LEU A 331 | NoneUDP A 503 ( 4.3A)NoneNone | 1.32A | 3ce6A-5u6sA:undetectable | 3ce6A-5u6sA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vha | DEAH(ASP-GLU-ALA-HIS)BOX POLYPEPTIDE 36 (Bos taurus) |
no annotation | 4 | THR A 577THR A 553HIS A 527LEU A 529 | None | 1.36A | 3ce6A-5vhaA:3.4 | 3ce6A-5vhaA:9.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w5f | TAIL TUBE PROTEINGP19 (Enterobacteriaphage T4 sensulato) |
PF06841(Phage_T4_gp19) | 4 | GLN A 35THR A 33THR A 39LEU A 157 | None | 1.28A | 3ce6A-5w5fA:undetectable | 3ce6A-5w5fA:17.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xog | DNA-DIRECTED RNAPOLYMERASE SUBUNITBETA (Komagataellaphaffii) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 4 | GLN B1065THR B1090HIS B1025LEU B1026 | None | 1.19A | 3ce6A-5xogB:undetectable | 3ce6A-5xogB:17.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zq6 | SIDE (Legionellapneumophila) |
no annotation | 4 | GLN A 272THR A 282HIS A 403LEU A 407 | NoneNoneADP A1101 (-4.0A)ADP A1101 (-4.8A) | 1.31A | 3ce6A-5zq6A:undetectable | 3ce6A-5zq6A:10.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6aph | ADENOSYLHOMOCYSTEINASE (Elizabethkingiaanophelis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 62THR A 63THR A 162HIS A 306LEU A 349 | ADN A 501 (-3.8A)ADN A 501 (-4.5A)NAD A 500 ( 2.9A)ADN A 501 ( 3.7A)NAD A 500 ( 4.3A) | 0.20A | 3ce6A-6aphA:56.3 | 3ce6A-6aphA:54.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bbo | APOBEC3H (Homo sapiens) |
no annotation | 4 | GLN A 33THR A 43HIS A 101LEU A 102 | None | 1.33A | 3ce6A-6bboA:undetectable | 3ce6A-6bboA:9.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c01 | ECTONUCLEOTIDEPYROPHOSPHATASE/PHOSPHODIESTERASE FAMILYMEMBER 3 (Homo sapiens) |
no annotation | 4 | GLN A 466THR A 378THR A 203HIS A 373 | NoneNoneNone ZN A 902 (-3.3A) | 1.09A | 3ce6A-6c01A:undetectable | 3ce6A-6c01A:8.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f2t | - (-) |
no annotation | 4 | GLN A 466THR A 379THR A 204HIS A 374 | NoneNoneNone ZN A1002 (-3.1A) | 1.11A | 3ce6A-6f2tA:undetectable | 3ce6A-6f2tA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f3m | - (-) |
no annotation | 5 | GLN B 65THR B 66THR B 165HIS B 323LEU B 373 | K B 504 ( 3.0A)ADN B 502 (-4.6A)NAD B 501 ( 2.8A) ZN B 505 (-3.2A)NAD B 501 ( 3.9A) | 0.53A | 3ce6A-6f3mB:52.2 | 3ce6A-6f3mB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gbn | - (-) |
no annotation | 5 | GLN A 60THR A 61THR A 160HIS A 304LEU A 347 | NA A 503 ( 3.2A)ADN A 501 (-4.6A)NAD A 502 ( 2.8A)ADN A 501 ( 3.6A)NAD A 502 (-3.9A) | 0.62A | 3ce6A-6gbnA:55.5 | 3ce6A-6gbnA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gmb | HYDROXYACID OXIDASE1 (Homo sapiens) |
no annotation | 4 | GLN A 350THR A 60THR A 64LEU A 304 | None | 1.13A | 3ce6A-6gmbA:undetectable | 3ce6A-6gmbA:12.76 |