SIMILAR PATTERNS OF AMINO ACIDS FOR 3C6G_A_VD3A701_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a59 | CITRATE SYNTHASE (AntarcticbacteriumDS2-3R) |
PF00285(Citrate_synt) | 5 | LEU A 126ALA A 195ALA A 203GLY A 105ILE A 346 | None | 1.07A | 3c6gA-1a59A:0.0 | 3c6gA-1a59A:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ais | PROTEIN(TRANSCRIPTIONINITIATION FACTORIIB) (Pyrococcuswoesei) |
PF00382(TFIIB) | 5 | LEU B1197ALA B1140ALA B1161GLY B1187ILE B1146 | None | 1.05A | 3c6gA-1aisB:0.2 | 3c6gA-1aisB:18.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cg4 | PROTEIN(ADENYLOSUCCINATESYNTHETASE) (Escherichiacoli) |
PF00709(Adenylsucc_synt) | 5 | LEU A 329ALA A 394THR A 406VAL A 315THR A 312 | None | 0.85A | 3c6gA-1cg4A:0.0 | 3c6gA-1cg4A:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ci9 | PROTEIN(CARBOXYLESTERASE) (Burkholderiagladioli) |
PF00144(Beta-lactamase) | 5 | LEU A 30ALA A 40ALA A 388THR A 372THR A 370 | None | 1.02A | 3c6gA-1ci9A:0.0 | 3c6gA-1ci9A:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cqj | SUCCINYL-COASYNTHETASE ALPHACHAIN (Escherichiacoli) |
PF00549(Ligase_CoA)PF02629(CoA_binding) | 5 | ALA A 84ALA A 114THR A 8VAL A 10ILE A 93 | None | 1.08A | 3c6gA-1cqjA:0.0 | 3c6gA-1cqjA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cvr | GINGIPAIN R (Porphyromonasgingivalis) |
PF01364(Peptidase_C25)PF03785(Peptidase_C25_C) | 5 | LEU A 260LEU A 146GLY A 201VAL A 190ILE A 148 | None | 1.07A | 3c6gA-1cvrA:0.0 | 3c6gA-1cvrA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cvr | GINGIPAIN R (Porphyromonasgingivalis) |
PF01364(Peptidase_C25)PF03785(Peptidase_C25_C) | 5 | LEU A 260LEU A 146GLY A 202VAL A 190ILE A 148 | None | 0.97A | 3c6gA-1cvrA:0.0 | 3c6gA-1cvrA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ece | ENDOCELLULASE E1 (Acidothermuscellulolyticus) |
PF00150(Cellulase) | 5 | ASN A 59ALA A 311GLY A 3VAL A 234ILE A 23 | None | 1.07A | 3c6gA-1eceA:0.0 | 3c6gA-1eceA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eg7 | FORMYLTETRAHYDROFOLATE SYNTHETASE (Moorellathermoacetica) |
PF01268(FTHFS) | 5 | LEU A1088ALA A1084GLY A1403ILE A1060THR A1077 | None | 1.07A | 3c6gA-1eg7A:0.0 | 3c6gA-1eg7A:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f3y | DIADENOSINE5',5'''-P1,P4-TETRAPHOSPHATE HYDROLASE (Lupinusangustifolius) |
PF00293(NUDIX) | 5 | LEU A 121ALA A 31GLY A 45VAL A 147THR A 146 | None | 1.05A | 3c6gA-1f3yA:0.0 | 3c6gA-1f3yA:17.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ggp | PROTEIN (LECTIN 1 ACHAIN)PROTEIN (LECTIN 1 BCHAIN) (Trichosantheskirilowii) |
PF00161(RIP)PF00652(Ricin_B_lectin) | 5 | LEU B 123ALA B 26GLY B 101THR A 212ILE B 62 | None | 1.03A | 3c6gA-1ggpB:undetectable | 3c6gA-1ggpB:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gq2 | MALIC ENZYME (Columba livia) |
PF00390(malic)PF03949(Malic_M) | 5 | LEU A 221LEU A 234GLY A 141VAL A 160MET A 202 | None | 1.03A | 3c6gA-1gq2A:undetectable | 3c6gA-1gq2A:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h7w | DIHYDROPYRIMIDINEDEHYDROGENASE (Sus scrofa) |
PF01180(DHO_dh)PF07992(Pyr_redox_2)PF14691(Fer4_20)PF14697(Fer4_21) | 5 | ALA A 486GLY A 284THR A 228VAL A 241ILE A 200 | NoneFAD A1031 (-3.6A)NoneNoneNone | 1.02A | 3c6gA-1h7wA:undetectable | 3c6gA-1h7wA:18.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k82 | FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE (Escherichiacoli) |
PF01149(Fapy_DNA_glyco)PF06827(zf-FPG_IleRS)PF06831(H2TH) | 6 | LEU A 196LEU A 157ALA A 178ALA A 203THR A 260ILE A 153 | None | 1.33A | 3c6gA-1k82A:undetectable | 3c6gA-1k82A:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mqt | POLYPROTEINPOLYPROTEIN CAPSIDPROTEIN (Enterovirus B) |
PF00073(Rhv) | 5 | LEU B 182PHE A 194THR A 246VAL C 40ILE C 46 | None | 1.06A | 3c6gA-1mqtB:undetectable | 3c6gA-1mqtB:18.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ofe | FERREDOXIN-DEPENDENTGLUTAMATE SYNTHASE 2 (Synechocystissp. PCC 6803) |
PF00310(GATase_2)PF01493(GXGXG)PF01645(Glu_synthase)PF04898(Glu_syn_central) | 5 | LEU A1373ALA A1397ALA A1429GLY A1390ILE A1360 | None | 1.07A | 3c6gA-1ofeA:undetectable | 3c6gA-1ofeA:15.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rw0 | CONSERVEDHYPOTHETICAL PROTEIN (Salmonellaenterica) |
PF02578(Cu-oxidase_4) | 5 | LEU A 11ALA A 17GLY A 213THR A 104VAL A 102 | None | 1.02A | 3c6gA-1rw0A:undetectable | 3c6gA-1rw0A:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sjp | 60 KDA CHAPERONIN 2 (Mycobacteriumtuberculosis) |
PF00118(Cpn60_TCP1) | 5 | LEU A 234ALA A 255THR A 327VAL A 320ILE A 217 | None | 1.03A | 3c6gA-1sjpA:undetectable | 3c6gA-1sjpA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ted | PKS18 (Mycobacteriumtuberculosis) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 5 | LEU A 231ALA A 374ALA A 176VAL A 360ILE A 35 | LEU A 231 ( 0.6A)ALA A 374 ( 0.0A)ALA A 176 ( 0.0A)VAL A 360 ( 0.6A)ILE A 35 ( 0.6A) | 0.89A | 3c6gA-1tedA:undetectable | 3c6gA-1tedA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tqy | ACTINORHODINPOLYKETIDE PUTATIVEBETA-KETOACYLSYNTHASE 2 (Streptomycescoelicolor) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | LEU B 387PHE B 218ALA B 306GLY B 298VAL B 291 | None | 0.95A | 3c6gA-1tqyB:undetectable | 3c6gA-1tqyB:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1up2 | CELA1 PROTEIN (Mycobacteriumtuberculosis) |
PF01341(Glyco_hydro_6) | 5 | LEU A 273ALA A 245ALA A 290GLY A 297VAL A 230 | None | 1.04A | 3c6gA-1up2A:undetectable | 3c6gA-1up2A:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wx0 | TRANSALDOLASE (Thermusthermophilus) |
PF00923(TAL_FSA) | 5 | LEU A 22ALA A 191GLY A 61THR A 7MET A 193 | None | 1.08A | 3c6gA-1wx0A:undetectable | 3c6gA-1wx0A:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xg2 | PECTINESTERASE 1 (Solanumlycopersicum) |
PF01095(Pectinesterase) | 5 | LEU A 168ALA A 136ALA A 112GLY A 150ILE A 197 | None | 1.08A | 3c6gA-1xg2A:undetectable | 3c6gA-1xg2A:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xzw | PURPLE ACIDPHOSPHATASE (Ipomoea batatas) |
PF00149(Metallophos)PF14008(Metallophos_C)PF16656(Pur_ac_phosph_N) | 5 | LEU A 283ALA A 157GLY A 162THR A 224ILE A 246 | None | 0.90A | 3c6gA-1xzwA:undetectable | 3c6gA-1xzwA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zun | SULFATEADENYLYLTRANSFERASESUBUNIT 2 (Pseudomonassyringae) |
PF01507(PAPS_reduct) | 5 | LEU A 84ALA A 46GLY A 133VAL A 205ILE A 35 | NoneNoneAGS A 600 (-2.9A)NoneNone | 1.05A | 3c6gA-1zunA:undetectable | 3c6gA-1zunA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dr1 | 386AA LONGHYPOTHETICAL SERINEAMINOTRANSFERASE (Pyrococcushorikoshii) |
PF00266(Aminotran_5) | 5 | ASN A 155ALA A 306GLY A 107ILE A 315THR A 351 | None | 1.05A | 3c6gA-2dr1A:undetectable | 3c6gA-2dr1A:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ebj | PYRROLIDONE CARBOXYLPEPTIDASE (Thermusthermophilus) |
PF01470(Peptidase_C15) | 5 | LEU A 147LEU A 62ALA A 110GLY A 65VAL A 117 | None | 1.04A | 3c6gA-2ebjA:undetectable | 3c6gA-2ebjA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2exa | PENICILLIN-BINDINGPROTEIN 4 (Escherichiacoli) |
PF02113(Peptidase_S13) | 5 | PHE A 315ALA A 148GLY A 332VAL A 373ILE A 348 | None | 0.99A | 3c6gA-2exaA:undetectable | 3c6gA-2exaA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gkw | TNFRECEPTOR-ASSOCIATEDFACTOR 3TUMOR NECROSISFACTOR RECEPTORSUPERFAMILY MEMBER13C (;Homo sapiens) |
no annotation | 5 | LEU A 396ALA A 392ALA B 165GLY A 398ILE A 358 | None | 1.00A | 3c6gA-2gkwA:undetectable | 3c6gA-2gkwA:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ibu | ACETYL-COAACETYLTRANSFERASE (Homo sapiens) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | LEU A 293ALA A 410ALA A 127GLY A 152ILE A 44 | NoneNoneCSO A 126 ( 3.6A)NoneNone | 1.02A | 3c6gA-2ibuA:undetectable | 3c6gA-2ibuA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j04 | YDR362CP (Saccharomycescerevisiae) |
no annotation | 5 | LEU B 298ALA B 658ALA B 558GLY B 575ILE B 285 | None | 0.97A | 3c6gA-2j04B:undetectable | 3c6gA-2j04B:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jss | CHIMERA OF HISTONEH2B.1 AND HISTONEH2A.Z (Saccharomycescerevisiae) |
PF00125(Histone)PF16211(Histone_H2A_C) | 5 | LEU A 48LEU A 115ALA A 65GLY A 126THR A 134 | None | 1.00A | 3c6gA-2jssA:undetectable | 3c6gA-2jssA:16.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k4w | SUPEROXIDE DISMUTASE[CU-ZN] (Salmonellaenterica) |
PF00080(Sod_Cu) | 5 | ALA A 149ALA A 66GLY A 71VAL A 5MET A 7 | None | 1.08A | 3c6gA-2k4wA:undetectable | 3c6gA-2k4wA:13.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v8j | PECTATE LYASE (Yersiniaenterocolitica) |
PF06917(Pectate_lyase_2) | 5 | LEU A 57ASN A 59PHE A 535GLY A 36THR A 529 | None | 1.00A | 3c6gA-2v8jA:undetectable | 3c6gA-2v8jA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vr3 | CLUMPING FACTOR A (Staphylococcusaureus) |
PF10425(SdrG_C_C) | 6 | LEU A 304ALA A 331ALA A 269THR A 359VAL A 241ILE A 277 | None | 1.45A | 3c6gA-2vr3A:undetectable | 3c6gA-2vr3A:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w2r | MATRIX PROTEIN (Vesicularstomatitisvirus) |
PF06326(Vesiculo_matrix) | 5 | LEU A 171ASN A 93ALA A 87ALA A 109GLY A 209 | None | 1.06A | 3c6gA-2w2rA:undetectable | 3c6gA-2w2rA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x3n | PROBABLEFAD-DEPENDENTMONOOXYGENASE (Pseudomonasaeruginosa) |
PF01494(FAD_binding_3) | 5 | LEU A 49ALA A 60ALA A 64GLY A 71ILE A 309 | None | 1.07A | 3c6gA-2x3nA:undetectable | 3c6gA-2x3nA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ab1 | FERREDOXIN--NADPREDUCTASE (Chlorobaculumtepidum) |
PF07992(Pyr_redox_2) | 5 | LEU A 268THR A 110VAL A 123ILE A 125THR A 18 | FAD A 361 (-4.5A)NoneNoneNoneNone | 1.05A | 3c6gA-3ab1A:undetectable | 3c6gA-3ab1A:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aii | GLUTAMYL-TRNASYNTHETASE (Methanothermobacterthermautotrophicus) |
PF00749(tRNA-synt_1c)PF03950(tRNA-synt_1c_C) | 5 | LEU A 531ALA A 537ALA A 520GLY A 545ILE A 505 | None | 1.05A | 3c6gA-3aiiA:undetectable | 3c6gA-3aiiA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aqi | FERROCHELATASE (Homo sapiens) |
PF00762(Ferrochelatase) | 5 | LEU A 371ASN A 374ALA A 382THR A 283VAL A 287 | None | 0.79A | 3c6gA-3aqiA:undetectable | 3c6gA-3aqiA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eqn | GLUCAN1,3-BETA-GLUCOSIDASE (Phanerochaetechrysosporium) |
PF12708(Pectate_lyase_3) | 5 | LEU A 558ALA A 519GLY A 600MET A 569THR A 607 | NoneNone ZN A 756 (-4.5A)NoneNone | 1.05A | 3c6gA-3eqnA:undetectable | 3c6gA-3eqnA:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gve | YFKN PROTEIN (Bacillussubtilis) |
PF00149(Metallophos) | 5 | LEU A 62LEU A 56ALA A 122ILE A 44THR A 320 | None | 1.05A | 3c6gA-3gveA:undetectable | 3c6gA-3gveA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hhe | RIBOSE-5-PHOSPHATEISOMERASE A (Bartonellahenselae) |
PF06026(Rib_5-P_isom_A) | 5 | LEU A 177ALA A 173GLY A 229ILE A 183THR A 166 | None | 0.91A | 3c6gA-3hheA:undetectable | 3c6gA-3hheA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k4y | ISOPENTENYLPHOSPHATE KINASE (Methanocaldococcusjannaschii) |
PF00696(AA_kinase) | 6 | LEU A 7PHE A 93ALA A 57GLY A 54ILE A 29THR A 100 | NoneNoneNoneIPE A 300 (-2.9A)NoneNone | 1.39A | 3c6gA-3k4yA:undetectable | 3c6gA-3k4yA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lup | DEGV FAMILY PROTEIN (Streptococcusagalactiae) |
PF02645(DegV) | 5 | LEU A 167ALA A 236GLY A 270ILE A 198THR A 120 | NoneNoneNoneNoneELA A 301 (-4.4A) | 0.96A | 3c6gA-3lupA:undetectable | 3c6gA-3lupA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lup | DEGV FAMILY PROTEIN (Streptococcusagalactiae) |
PF02645(DegV) | 5 | LEU A 167ALA A 275ALA A 236ILE A 198THR A 120 | NoneELA A 301 ( 4.2A)NoneNoneELA A 301 (-4.4A) | 1.07A | 3c6gA-3lupA:undetectable | 3c6gA-3lupA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mfd | D-ALANYL-D-ALANINECARBOXYPEPTIDASEDACB (Bacillussubtilis) |
PF00768(Peptidase_S11)PF07943(PBP5_C) | 5 | LEU A 104ALA A 70ALA A 122GLY A 116ILE A 187 | None | 0.96A | 3c6gA-3mfdA:undetectable | 3c6gA-3mfdA:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mpn | TRANSPORTER (Aquifexaeolicus) |
PF00209(SNF) | 5 | LEU A 183ASN A 179ALA A 198GLY A 190THR A 264 | None | 1.00A | 3c6gA-3mpnA:undetectable | 3c6gA-3mpnA:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3my7 | ALCOHOLDEHYDROGENASE/ACETALDEHYDE DEHYDROGENASE (Vibrioparahaemolyticus) |
PF00171(Aldedh) | 5 | LEU A 191ALA A 201GLY A 211VAL A 104ILE A 107 | None | 1.06A | 3c6gA-3my7A:undetectable | 3c6gA-3my7A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3myb | ENOYL-COA HYDRATASE (Mycolicibacteriumsmegmatis) |
PF00378(ECH_1) | 5 | LEU A 178LEU A 162ALA A 118ALA A 109GLY A 135 | NoneNoneNoneNoneGOL A 300 (-4.1A) | 0.95A | 3c6gA-3mybA:undetectable | 3c6gA-3mybA:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3otx | ADENOSINE KINASE,PUTATIVE (Trypanosomabrucei) |
PF00294(PfkB) | 6 | LEU A 39LEU A 32ALA A 136ALA A 198GLY A 35ILE A 47 | NoneNoneAP5 A 346 (-3.5A)NoneNoneNone | 1.19A | 3c6gA-3otxA:undetectable | 3c6gA-3otxA:23.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pyg | 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE (Mycobacteriumtuberculosis) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 5 | LEU A 218ALA A 262ALA A 271THR A 149VAL A 34 | None | 1.03A | 3c6gA-3pygA:undetectable | 3c6gA-3pygA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q9c | ACETYLPOLYAMINEAMIDOHYDROLASE (Mycoplanaramosa) |
PF00850(Hist_deacetyl) | 5 | ASN A 173ALA A 127ALA A 33GLY A 321THR A 118 | NoneNoneNoneQ9C A 401 (-3.6A)None | 0.93A | 3c6gA-3q9cA:undetectable | 3c6gA-3q9cA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qvl | PUTATIVE HYDANTOINRACEMASE (Klebsiellapneumoniae) |
PF01177(Asp_Glu_race) | 5 | ALA A 78ALA A 88GLY A 67ILE A 35THR A 18 | None | 0.99A | 3c6gA-3qvlA:undetectable | 3c6gA-3qvlA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tr3 | BOLA (Coxiellaburnetii) |
PF01722(BolA) | 5 | LEU A 55ALA A 23GLY A 14VAL A 2ILE A 63 | None | 0.92A | 3c6gA-3tr3A:undetectable | 3c6gA-3tr3A:11.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ac3 | BIFUNCTIONAL PROTEINGLMU (Streptococcuspneumoniae) |
PF00132(Hexapep)PF00483(NTP_transferase)PF14602(Hexapep_2) | 5 | LEU A 292ALA A 329GLY A 295VAL A 266ILE A 286 | None | 1.06A | 3c6gA-4ac3A:undetectable | 3c6gA-4ac3A:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bi9 | 3-KETOACYL-COATHIOLASE, PUTATIVE (Trypanosomabrucei) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | LEU A 52LEU A 60ASN A 57ALA A 96GLY A 19 | None | 0.98A | 3c6gA-4bi9A:undetectable | 3c6gA-4bi9A:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cak | INTEGRIN BETA-3 (Homo sapiens) |
PF00362(Integrin_beta)PF07965(Integrin_B_tail)PF07974(EGF_2)PF17205(PSI_integrin) | 5 | LEU B 138ALA B 347THR B 146VAL B 112ILE B 114 | None | 1.08A | 3c6gA-4cakB:undetectable | 3c6gA-4cakB:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e69 | 2-DEHYDRO-3-DEOXYGLUCONOKINASE (Oceanicolagranulosus) |
PF00294(PfkB) | 5 | LEU A 190ALA A 281GLY A 255VAL A 125ILE A 188 | None | 1.06A | 3c6gA-4e69A:undetectable | 3c6gA-4e69A:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e79 | UDP-3-O-ACYLGLUCOSAMINEN-ACYLTRANSFERASE (Acinetobacterbaumannii) |
PF00132(Hexapep)PF04613(LpxD)PF14602(Hexapep_2) | 5 | LEU A 171GLY A 209VAL A 163ILE A 165THR A 181 | None | 1.01A | 3c6gA-4e79A:undetectable | 3c6gA-4e79A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ggj | MITOCHONDRIALCARDIOLIPINHYDROLASE (Mus musculus) |
PF13091(PLDc_2) | 5 | LEU A 84PHE A 98GLY A 104VAL A 183ILE A 165 | None | 0.92A | 3c6gA-4ggjA:undetectable | 3c6gA-4ggjA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hea | NADH-QUINONEOXIDOREDUCTASESUBUNIT 13 (Thermusthermophilus) |
PF00361(Proton_antipo_M) | 6 | LEU M 100LEU M 233ALA M 29ALA M 89GLY M 324ILE M 78 | None | 1.39A | 3c6gA-4heaM:undetectable | 3c6gA-4heaM:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4itu | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Xanthobacterautotrophicus) |
PF13561(adh_short_C2) | 5 | LEU A 88ALA A 122ALA A 35GLY A 16THR A 66 | NoneNoneNoneNAI A 301 ( 4.6A)NAI A 301 ( 4.5A) | 1.03A | 3c6gA-4ituA:undetectable | 3c6gA-4ituA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jqo | ORNITHINECARBAMOYLTRANSFERASE (Vibriovulnificus) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | LEU A 11ASN A 9ALA A 95ALA A 50GLY A 129 | None | 1.05A | 3c6gA-4jqoA:undetectable | 3c6gA-4jqoA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lc9 | GLUCOKINASEREGULATORY PROTEIN (Rattusnorvegicus) |
no annotation | 5 | LEU A 576LEU A 501ALA A 604ALA A 594GLY A 498 | None | 1.08A | 3c6gA-4lc9A:undetectable | 3c6gA-4lc9A:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4md8 | CASEIN KINASE IISUBUNIT ALPHA (Homo sapiens) |
PF00069(Pkinase) | 5 | LEU E 41ALA E 56ALA E 110GLY E 34ILE E 59 | None | 1.07A | 3c6gA-4md8E:undetectable | 3c6gA-4md8E:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n0v | GLUTATHIONES-TRANSFERASE,N-TERMINAL DOMAIN (Marinobacterhydrocarbonoclasticus) |
PF13409(GST_N_2)PF14497(GST_C_3) | 5 | ALA A 18ALA A 172GLY A 8ILE A 3THR A 25 | None | 0.91A | 3c6gA-4n0vA:undetectable | 3c6gA-4n0vA:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ohc | OROTATEPHOSPHORIBOSYLTRANSFERASE (Burkholderiacenocepacia) |
PF00156(Pribosyltran) | 5 | LEU A 179LEU A 127ALA A 181GLY A 80ILE A 66 | None | 1.05A | 3c6gA-4ohcA:undetectable | 3c6gA-4ohcA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qnl | TAIL FIBER PROTEIN (Escherichiavirus G7C) |
no annotation | 5 | ALA A 433GLY A 444THR A 490VAL A 254ILE A 376 | None | 1.06A | 3c6gA-4qnlA:undetectable | 3c6gA-4qnlA:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qnx | TRNA(MO5U34)-METHYLTRANSFERASE (Escherichiacoli) |
PF08003(Methyltransf_9) | 5 | LEU A 156PHE A 94ALA A 163MET A 289THR A 286 | None | 1.07A | 3c6gA-4qnxA:undetectable | 3c6gA-4qnxA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ubt | ACETYL-COAACETYLTRANSFERASEFADA5 (Mycobacteriumtuberculosis) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | LEU A 128PHE A 318ALA A 378ALA A 154THR A 352 | 3G6 A 402 ( 4.3A)None3G6 A 402 (-4.1A)NoneNone | 1.05A | 3c6gA-4ubtA:undetectable | 3c6gA-4ubtA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wr2 | PYRIMIDINE-SPECIFICRIBONUCLEOSIDEHYDROLASE RIHA (Shewanellaloihica) |
PF01156(IU_nuc_hydro) | 5 | LEU A 195GLY A 171THR A 320VAL A 307ILE A 230 | None CA A 401 ( 4.1A)NoneNoneNone | 0.96A | 3c6gA-4wr2A:undetectable | 3c6gA-4wr2A:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wv3 | ANTHRANILATE-COALIGASE (Stigmatellaaurantiaca) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 5 | LEU A 287ALA A 273ALA A 304GLY A 310ILE A 255 | None | 1.07A | 3c6gA-4wv3A:undetectable | 3c6gA-4wv3A:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xz7 | PUTATIVEUNCHARACTERIZEDPROTEIN (Streptococcussuis) |
PF01841(Transglut_core) | 5 | PHE A 369ALA A 309ALA A 257VAL A 323THR A 335 | None | 1.06A | 3c6gA-4xz7A:undetectable | 3c6gA-4xz7A:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b47 | 2-OXOACID--FERREDOXIN OXIDOREDUCTASEALPHA SUBUNIT (Sulfurisphaeratokodaii) |
PF01558(POR)PF01855(POR_N)PF17147(PFOR_II) | 5 | LEU A 364GLY A 317THR A 313VAL A 337ILE A 327 | None | 0.93A | 3c6gA-5b47A:undetectable | 3c6gA-5b47A:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eks | 3-DEHYDROQUINATESYNTHASE (Acinetobacterbaumannii) |
PF01761(DHQ_synthase) | 5 | LEU A 27PHE A 123GLY A 107VAL A 6ILE A 15 | None | 1.06A | 3c6gA-5eksA:undetectable | 3c6gA-5eksA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f1n | BETA-2-MICROGLOBULINMHC CLASS I ANTIGEN (Canis lupus) |
PF00129(MHC_I)PF07654(C1-set) | 5 | ALA B 27GLY B 56THR A 10VAL A 12THR A 94 | None | 1.07A | 3c6gA-5f1nB:undetectable | 3c6gA-5f1nB:16.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f42 | ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINEO-ACYLTRANSFERASE (Francisellatularensis) |
PF00132(Hexapep)PF13720(Acetyltransf_11) | 5 | LEU A 130ALA A 164ALA A 170GLY A 135ILE A 128 | None | 1.04A | 3c6gA-5f42A:undetectable | 3c6gA-5f42A:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f4z | EPOXIDE HYDROLASE (Streptomycescarzinostaticus) |
PF06441(EHN) | 5 | LEU A 176ALA A 338GLY A 174THR A 183ILE A 307 | None5V4 A 408 (-3.5A)NoneNoneNone | 1.04A | 3c6gA-5f4zA:undetectable | 3c6gA-5f4zA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5huq | LACTATE RACEMIZATIONOPERON PROTEIN LARA (Lactobacillusplantarum) |
PF09861(DUF2088) | 5 | ALA A 274GLY A 24VAL A 316ILE A 314THR A 283 | None | 1.03A | 3c6gA-5huqA:undetectable | 3c6gA-5huqA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i33 | ADENYLOSUCCINATESYNTHETASE (Cryptococcusneoformans) |
PF00709(Adenylsucc_synt) | 5 | LEU A 96ALA A 61GLY A 41VAL A 305THR A 304 | None | 1.02A | 3c6gA-5i33A:undetectable | 3c6gA-5i33A:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i5h | INNER MEMBRANEPROTEIN YEJM (Escherichiacoli) |
PF00884(Sulfatase)PF11893(DUF3413) | 5 | LEU A 503LEU A 494ALA A 329GLY A 308ILE A 446 | None | 1.03A | 3c6gA-5i5hA:undetectable | 3c6gA-5i5hA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ijg | CYS/MET METABOLISMPYRIDOXAL-PHOSPHATE-DEPENDENT ENZYME (Brucellamelitensis) |
PF01053(Cys_Met_Meta_PP) | 5 | LEU A 139ALA A 214GLY A 134VAL A 119ILE A 125 | None | 0.87A | 3c6gA-5ijgA:undetectable | 3c6gA-5ijgA:23.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l0z | PROBABLE RNAMETHYLTRANSFERASE,TRMH FAMILY (Sinorhizobiummeliloti) |
PF00588(SpoU_methylase)PF08032(SpoU_sub_bind) | 5 | LEU A 165ALA A 155THR A 177ILE A 190THR A 181 | None | 1.07A | 3c6gA-5l0zA:undetectable | 3c6gA-5l0zA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l26 | NUCLEOSIDE PERMEASE (Neisseriawadsworthii) |
PF01773(Nucleos_tra2_N)PF07662(Nucleos_tra2_C)PF07670(Gate) | 5 | ALA A 367ALA A 205GLY A 186THR A 155VAL A 374 | NoneNone6ZL A 501 ( 4.4A)URI A 505 ( 4.5A)URI A 505 (-4.6A) | 1.05A | 3c6gA-5l26A:undetectable | 3c6gA-5l26A:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mov | CASEIN KINASE IISUBUNIT ALPHA (Homo sapiens) |
PF00069(Pkinase) | 5 | LEU A 41ALA A 56ALA A 110GLY A 34ILE A 59 | None | 1.01A | 3c6gA-5movA:undetectable | 3c6gA-5movA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nd1 | CAPSID PROTEIN (Rosellinianecatrixquadrivirus 1) |
no annotation | 5 | LEU B 154ALA B 105GLY B 819THR B 494ILE B 487 | None | 0.98A | 3c6gA-5nd1B:undetectable | 3c6gA-5nd1B:13.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t5i | TUNGSTENFORMYLMETHANOFURANDEHYDROGENASESUBUNIT FWDFTUNGSTENFORMYLMETHANOFURANDEHYDROGENASESUBUNIT FWDG (Methanothermobacterwolfeii) |
PF00037(Fer4)PF12838(Fer4_7) | 5 | LEU G 5ALA G 21GLY G 62THR F 57ILE G 76 | SF4 G 102 ( 4.6A)NoneSF4 G 102 (-4.3A)NoneSF4 G 101 ( 3.8A) | 1.07A | 3c6gA-5t5iG:undetectable | 3c6gA-5t5iG:9.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uth | THIOREDOXINREDUCTASE (Mycolicibacteriumsmegmatis) |
PF07992(Pyr_redox_2) | 5 | LEU A 307ALA A 109ALA A 26GLY A 296VAL A 253 | None | 1.08A | 3c6gA-5uthA:undetectable | 3c6gA-5uthA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vjw | RHIZOBIALES-LIKEPHOSPHATASE 2 (Arabidopsisthaliana) |
no annotation | 5 | LEU A 28LEU A 62ALA A 292ALA A 40ILE A 14 | None | 0.95A | 3c6gA-5vjwA:undetectable | 3c6gA-5vjwA:11.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vmk | BIFUNCTIONAL PROTEINGLMU (Acinetobacterbaumannii) |
PF00132(Hexapep)PF12804(NTP_transf_3)PF14602(Hexapep_2) | 5 | LEU A 295GLY A 314VAL A 287ILE A 289THR A 304 | None | 0.95A | 3c6gA-5vmkA:undetectable | 3c6gA-5vmkA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vqd | BETA-GLUCOSIDEPHOSPHORYLASE BGLX (unidentified) |
no annotation | 5 | ASN A 161ALA A 111GLY A 100ILE A 485THR A 419 | None | 1.07A | 3c6gA-5vqdA:undetectable | 3c6gA-5vqdA:10.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w0s | 60 KDA CHAPERONIN (Escherichiacoli) |
PF00118(Cpn60_TCP1) | 5 | LEU A 237ALA A 258THR A 330VAL A 323ILE A 220 | None | 0.99A | 3c6gA-5w0sA:undetectable | 3c6gA-5w0sA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wql | TAIL-SPECIFICPROTEASE (Escherichiacoli) |
no annotation | 5 | LEU C 392ASN C 395VAL C 373ILE C 362THR C 370 | None | 0.91A | 3c6gA-5wqlC:undetectable | 3c6gA-5wqlC:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yu1 | LYSINECYCLODEAMINASE (Streptomycespristinaespiralis) |
no annotation | 5 | LEU A 143ALA A 156GLY A 147VAL A 188THR A 186 | NoneNoneNAD A 402 (-3.3A)NoneNone | 1.03A | 3c6gA-5yu1A:undetectable | 3c6gA-5yu1A:8.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yx9 | SHORT TRANSIENTRECEPTOR POTENTIALCHANNEL 6 (Homo sapiens) |
no annotation | 5 | LEU A 192PHE A 186ALA A 243GLY A 162THR A 237 | None | 1.06A | 3c6gA-5yx9A:undetectable | 3c6gA-5yx9A:9.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c2j | RNAP2 (Escherichiavirus N4) |
no annotation | 5 | LEU B 145LEU B 87GLY B 89VAL B 251ILE B 247 | None | 1.06A | 3c6gA-6c2jB:undetectable | 3c6gA-6c2jB:12.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dux | 6-PHOSPHO-ALPHA-GLUCOSIDASE (Klebsiellapneumoniae) |
no annotation | 5 | LEU A 428ALA A 284VAL A 415ILE A 424THR A 414 | None | 0.96A | 3c6gA-6duxA:undetectable | 3c6gA-6duxA:12.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6et9 | ACETYL-COAACETYLTRANSFERASETHIOLASE (Methanothermococcusthermolithotrophicus) |
no annotation | 5 | LEU A 216ALA A 373ALA A 86GLY A 111ILE A 6 | None | 1.03A | 3c6gA-6et9A:undetectable | 3c6gA-6et9A:10.76 |