SIMILAR PATTERNS OF AMINO ACIDS FOR 3BOG_D_DVAD47_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e5m BETA KETOACYL ACYL
CARRIER PROTEIN
SYNTHASE II

(Synechocystis
sp. PCC 6803) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 GLY A 192
GLY A 351
GLY A 348
GLY A 240
 None
 0.60A 3bogD-1e5mA:
0.0		 3bogD-1e5mA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h5o MYOTOXIN

(Crotalus
durissus) 		PF00819
(Myotoxins) 		4 GLY A  40
GLY A   8
GLY A   9
GLY A  42
 None
 0.67A 3bogD-1h5oA:
0.0		 3bogD-1h5oA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  12
GLY A 119
GLY A  41
GLY A 146
 None
 0.62A 3bogD-1lnzA:
0.0		 3bogD-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  18
GLY A  38
GLY A  16
GLY A  72
 None
 0.63A 3bogD-1lnzA:
0.0		 3bogD-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  38
GLY A  72
GLY A  36
GLY A  79
 None
 0.68A 3bogD-1lnzA:
0.0		 3bogD-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A 120
GLY A  15
GLY A  39
GLY A  41
 None
 0.61A 3bogD-1lnzA:
0.0		 3bogD-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgj 6-PHOSPHOGLUCONATE
DEHYDROGENASE

(Trypanosoma
brucei) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 GLY A 179
GLY A 145
GLY A 176
GLY A 181
 None
 0.56A 3bogD-1pgjA:
0.0		 3bogD-1pgjA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgp 6-PHOSPHOGLUCONATE
DEHYDROGENASE

(Ovis aries) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 GLY A 177
GLY A 143
GLY A 174
GLY A 179
 None
 0.65A 3bogD-1pgpA:
undetectable		 3bogD-1pgpA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1)
PF09269
(DUF1967) 		4 GLY A  15
GLY A  41
GLY A  13
GLY A  68
 None
 0.67A 3bogD-1udxA:
0.1		 3bogD-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1)
PF09269
(DUF1967) 		4 GLY A  15
GLY A 121
GLY A  38
GLY A 142
 None
 0.63A 3bogD-1udxA:
0.1		 3bogD-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1)
PF09269
(DUF1967) 		4 GLY A  18
GLY A  38
GLY A  16
GLY A  71
 None
 0.68A 3bogD-1udxA:
0.1		 3bogD-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ur4 GALACTANASE

(Bacillus
licheniformis) 		PF07745
(Glyco_hydro_53) 		4 GLY A  84
GLY A  82
GLY A  80
GLY A 344
 None
 0.68A 3bogD-1ur4A:
0.0		 3bogD-1ur4A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vpd TARTRONATE
SEMIALDEHYDE
REDUCTASE

(Salmonella
enterica) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 GLY A 166
GLY A 139
GLY A 163
GLY A 168
 None
 0.55A 3bogD-1vpdA:
undetectable		 3bogD-1vpdA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wv2 THIAZOLE
BIOSYNTHESIS PROTEIN
THIG

(Pseudomonas
aeruginosa) 		PF05690
(ThiG) 		4 GLY A1168
GLY A1195
GLY A1165
GLY A1170
 None
 0.63A 3bogD-1wv2A:
0.0		 3bogD-1wv2A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yb4 TARTRONIC
SEMIALDEHYDE
REDUCTASE

(Salmonella
enterica) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 GLY A 163
GLY A 136
GLY A 160
GLY A 165
 None
 0.54A 3bogD-1yb4A:
undetectable		 3bogD-1yb4A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE

(Archaeoglobus
fulgidus) 		PF01238
(PMI_typeI) 		4 GLY A  21
GLY A  20
GLY A  36
GLY A  34
 None
 0.66A 3bogD-1zx5A:
undetectable		 3bogD-1zx5A:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bu2 PYRUVATE
DEHYDROGENSAE KINASE
ISOENZYME 2

(Homo sapiens) 		PF02518
(HATPase_c)
PF10436
(BCDHK_Adom3) 		4 GLY A 284
GLY A 286
GLY A 343
GLY A 345
 None
ATP  A1386 ( 4.9A)
None
None
 0.63A 3bogD-2bu2A:
undetectable		 3bogD-2bu2A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c7z 3-KETOACYL-COA
THIOLASE 2

(Arabidopsis
thaliana) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 GLY A 141
GLY A 103
GLY A 164
GLY A 396
 None
 0.61A 3bogD-2c7zA:
undetectable		 3bogD-2c7zA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cvz 3-HYDROXYISOBUTYRATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 GLY A 159
GLY A 133
GLY A 156
GLY A 161
 None
 0.56A 3bogD-2cvzA:
undetectable		 3bogD-2cvzA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fx5 LIPASE

(Pseudomonas
mendocina) 		no annotation 4 GLY A  88
GLY A 128
GLY A  55
GLY A 131
 None
 0.65A 3bogD-2fx5A:
undetectable		 3bogD-2fx5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fx5 LIPASE

(Pseudomonas
mendocina) 		no annotation 4 GLY A 124
GLY A 128
GLY A 131
GLY A  55
 None
 0.67A 3bogD-2fx5A:
undetectable		 3bogD-2fx5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gf2 3-HYDROXYISOBUTYRATE
DEHYDROGENASE

(Homo sapiens) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 GLY A 203
GLY A 176
GLY A 200
GLY A 205
 None
 0.58A 3bogD-2gf2A:
undetectable		 3bogD-2gf2A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Staphylococcus
aureus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 GLY A 344
GLY A 191
GLY A 107
GLY A 168
 None
 0.66A 3bogD-2gqdA:
undetectable		 3bogD-2gqdA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ivp O-SIALOGLYCOPROTEIN
ENDOPEPTIDASE

(Pyrococcus
abyssi) 		PF00814
(Peptidase_M22) 		4 GLY A   5
GLY A 287
GLY A  14
GLY A  16
 None
 0.55A 3bogD-2ivpA:
undetectable		 3bogD-2ivpA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iyo 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING

(Lactococcus
lactis) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 GLY A 178
GLY A 143
GLY A 175
GLY A 180
 None
 0.60A 3bogD-2iyoA:
undetectable		 3bogD-2iyoA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j6d CONKUNITZIN-S2

(Conus striatus) 		PF00014
(Kunitz_BPTI) 		4 GLY A  19
GLY A  17
GLY A  44
GLY A  42
 None
 0.68A 3bogD-2j6dA:
undetectable		 3bogD-2j6dA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jf7 STRICTOSIDINE-O-BETA
-D-GLUCOSIDASE

(Rauvolfia
serpentina) 		PF00232
(Glyco_hydro_1) 		4 GLY A 215
GLY A 219
GLY A 226
GLY A 224
 None
 0.48A 3bogD-2jf7A:
undetectable		 3bogD-2jf7A:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4q 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING 1

(Saccharomyces
cerevisiae) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 GLY A 176
GLY A 143
GLY A 173
GLY A 178
 None
 0.65A 3bogD-2p4qA:
undetectable		 3bogD-2p4qA:
12.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  18
GLY A  36
GLY A  46
GLY A   9
 None
 0.65A 3bogD-2pneA:
18.1		 3bogD-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  30
GLY A  52
GLY A  21
GLY A  61
 None
 0.64A 3bogD-2pneA:
18.1		 3bogD-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  33
GLY A  51
GLY A  61
GLY A  21
 None
 0.66A 3bogD-2pneA:
18.1		 3bogD-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  36
GLY A  18
GLY A  34
GLY A   9
 None
 0.68A 3bogD-2pneA:
18.1		 3bogD-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  36
GLY A  46
GLY A  15
GLY A  67
 None
 0.68A 3bogD-2pneA:
18.1		 3bogD-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  36
GLY A  48
GLY A  64
GLY A  18
 None
 0.67A 3bogD-2pneA:
18.1		 3bogD-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  39
GLY A  45
GLY A  67
GLY A  15
 None
 0.65A 3bogD-2pneA:
18.1		 3bogD-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  48
GLY A  36
GLY A  46
GLY A  18
 None
 0.68A 3bogD-2pneA:
18.1		 3bogD-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  48
GLY A  66
GLY A  73
GLY A  36
 None
 0.63A 3bogD-2pneA:
18.1		 3bogD-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  51
GLY A  63
GLY A  76
GLY A  33
 None
 0.66A 3bogD-2pneA:
18.1		 3bogD-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  67
GLY A  45
GLY A  69
GLY A  73
 None
 0.68A 3bogD-2pneA:
18.1		 3bogD-2pneA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2por PORIN

(Rhodobacter
capsulatus) 		PF13609
(Porin_4) 		4 GLY A  90
GLY A 280
GLY A 266
GLY A 279
 None
C8E  A 546 (-3.9A)
C8E  A 546 ( 4.4A)
C8E  A 546 ( 4.3A)
 0.65A 3bogD-2porA:
undetectable		 3bogD-2porA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q8h [PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1

(Homo sapiens) 		PF02518
(HATPase_c)
PF10436
(BCDHK_Adom3) 		4 GLY A 320
GLY A 322
GLY A 380
GLY A 382
 None
 0.64A 3bogD-2q8hA:
undetectable		 3bogD-2q8hA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vwb PUTATIVE
O-SIALOGLYCOPROTEIN
ENDOPEPTIDASE

(Methanocaldococcus
jannaschii) 		PF00814
(Peptidase_M22)
PF01163
(RIO1) 		4 GLY A   5
GLY A 286
GLY A  14
GLY A  16
 None
 0.58A 3bogD-2vwbA:
undetectable		 3bogD-2vwbA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w8z 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING

(Geobacillus
stearothermophilus) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 GLY A 176
GLY A 143
GLY A 173
GLY A 178
 None
 0.59A 3bogD-2w8zA:
undetectable		 3bogD-2w8zA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyg 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING

(Klebsiella
pneumoniae) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 GLY A 177
GLY A 143
GLY A 174
GLY A 179
 None
 0.56A 3bogD-2zygA:
undetectable		 3bogD-2zygA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ak5 HEMOGLOBIN-BINDING
PROTEASE HBP

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		4 GLY A 378
GLY A 355
GLY A 346
GLY A 376
 None
 0.68A 3bogD-3ak5A:
undetectable		 3bogD-3ak5A:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus) 		PF03069
(FmdA_AmdA) 		4 GLY A 156
GLY A 154
GLY A 145
GLY A 143
 None
 0.64A 3bogD-3b9tA:
undetectable		 3bogD-3b9tA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  30
GLY A  52
GLY A  21
GLY A  61
 None
 0.65A 3bogD-3bogA:
18.5		 3bogD-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  33
GLY A  21
GLY A  31
GLY A   6
 None
 0.67A 3bogD-3bogA:
18.5		 3bogD-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  33
GLY A  51
GLY A  61
GLY A  21
 None
 0.62A 3bogD-3bogA:
18.5		 3bogD-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  36
GLY A  18
GLY A  34
GLY A   9
 None
 0.57A 3bogD-3bogA:
18.5		 3bogD-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  36
GLY A  48
GLY A  64
GLY A  18
 None
 0.66A 3bogD-3bogA:
18.5		 3bogD-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  39
GLY A  45
GLY A  67
GLY A  15
 None
None
None
SYS  A  11 ( 4.3A)
 0.67A 3bogD-3bogA:
18.5		 3bogD-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  48
GLY A  36
GLY A  46
GLY A  18
 None
 0.66A 3bogD-3bogA:
18.5		 3bogD-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  48
GLY A  66
GLY A  73
GLY A  36
 None
 0.62A 3bogD-3bogA:
18.5		 3bogD-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  63
GLY A  51
GLY A  61
GLY A  33
 None
 0.63A 3bogD-3bogA:
18.5		 3bogD-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cky 2-HYDROXYMETHYL
GLUTARATE
DEHYDROGENASE

(Eubacterium
barkeri) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 GLY A 168
GLY A 141
GLY A 165
GLY A 170
 None
 0.53A 3bogD-3ckyA:
undetectable		 3bogD-3ckyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iln LAMINARINASE

(Rhodothermus
marinus) 		PF00722
(Glyco_hydro_16) 		4 GLY A 231
GLY A 105
GLY A 235
GLY A 227
 None
 0.66A 3bogD-3ilnA:
undetectable		 3bogD-3ilnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3me1 UREA TRANSPORTER

(Desulfovibrio
vulgaris) 		PF03253
(UT) 		4 GLY A 107
GLY A  55
GLY A  86
GLY A  82
 None
 0.66A 3bogD-3me1A:
undetectable		 3bogD-3me1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE

(Bacteroides
ovatus) 		no annotation 4 GLY A 239
GLY A 273
GLY A 267
GLY A 269
 None
 0.68A 3bogD-3n6zA:
undetectable		 3bogD-3n6zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q3c PROBABLE
3-HYDROXYISOBUTYRATE
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 GLY A 165
GLY A 138
GLY A 162
GLY A 167
 None
 0.48A 3bogD-3q3cA:
undetectable		 3bogD-3q3cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qha PUTATIVE
OXIDOREDUCTASE

(Mycobacterium
avium) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 GLY A 171
GLY A 144
GLY A 168
GLY A 173
 None
 0.53A 3bogD-3qhaA:
undetectable		 3bogD-3qhaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ss6 ACETYL-COA
ACETYLTRANSFERASE

(Bacillus
anthracis) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 GLY A 344
GLY A 346
GLY A 247
GLY A 342
 None
 0.65A 3bogD-3ss6A:
undetectable		 3bogD-3ss6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u5u RAUCAFFRICINE-O-BETA
-D-GLUCOSIDASE

(Rauvolfia
serpentina) 		PF00232
(Glyco_hydro_1) 		4 GLY A 194
GLY A 198
GLY A 205
GLY A 203
 None
 0.47A 3bogD-3u5uA:
undetectable		 3bogD-3u5uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ugv ENOLASE

(alpha
proteobacterium
BAL199) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 GLY A 342
GLY A 166
GLY A 164
GLY A 162
 None
 0.42A 3bogD-3ugvA:
undetectable		 3bogD-3ugvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dll 2-HYDROXY-3-OXOPROPI
ONATE REDUCTASE

(Polaromonas sp.
JS666) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 GLY A 193
GLY A 167
GLY A 190
GLY A 195
 None
 0.54A 3bogD-4dllA:
undetectable		 3bogD-4dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e21 6-PHOSPHOGLUCONATE
DEHYDROGENASE
(DECARBOXYLATING)

(Geobacter
metallireducens) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 GLY A 182
GLY A 135
GLY A 179
GLY A 184
 None
 0.56A 3bogD-4e21A:
undetectable		 3bogD-4e21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e54 DNA DAMAGE-BINDING
PROTEIN 2

(Homo sapiens) 		PF00400
(WD40) 		4 GLY B 157
GLY B 154
GLY B 152
GLY B 133
 None
 0.61A 3bogD-4e54B:
undetectable		 3bogD-4e54B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fay MICROCOMPARTMENTS
PROTEIN

(Lactobacillus
reuteri) 		PF00936
(BMC) 		4 GLY A 159
GLY A 165
GLY A 163
GLY A 196
 None
 0.66A 3bogD-4fayA:
undetectable		 3bogD-4fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4imp POLYKETIDE SYNTHASE
EXTENDER MODULES 3-4

(Saccharopolyspora
spinosa) 		PF08659
(KR) 		4 GLY A 209
GLY A 415
GLY A 418
GLY A 426
 None
 0.67A 3bogD-4impA:
undetectable		 3bogD-4impA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jas HISTIDINE KINASE

(Thermotoga
maritima) 		PF00512
(HisKA)
PF02518
(HATPase_c) 		4 GLY A 413
GLY A 415
GLY A 467
GLY A 469
 None
ADP  A 501 (-4.7A)
None
None
 0.64A 3bogD-4jasA:
undetectable		 3bogD-4jasA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Pseudomonas
aeruginosa) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 GLY A 167
GLY A 190
GLY A 106
GLY A 189
 None
 0.65A 3bogD-4jb6A:
undetectable		 3bogD-4jb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jga 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Rickettsia
rickettsii) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 GLY A 180
GLY A 203
GLY A 119
GLY A 202
 None
 0.60A 3bogD-4jgaA:
undetectable		 3bogD-4jgaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jrm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Vibrio cholerae) 		no annotation 4 GLY D 167
GLY D 190
GLY D 106
GLY D 189
 None
 0.56A 3bogD-4jrmD:
undetectable		 3bogD-4jrmD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Neisseria
meningitidis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 GLY A 168
GLY A 191
GLY A 107
GLY A 190
 None
 0.67A 3bogD-4qavA:
undetectable		 3bogD-4qavA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r8e 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Yersinia pestis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 GLY A 166
GLY A 189
GLY A 105
GLY A 188
 None
 0.65A 3bogD-4r8eA:
undetectable		 3bogD-4r8eA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzf 1,3-BETA-GLUCANASE

(Mycobacterium
tuberculosis) 		PF00722
(Glyco_hydro_16) 		4 GLY A 154
GLY A 275
GLY A 273
GLY A 270
 None
 0.62A 3bogD-4wzfA:
undetectable		 3bogD-4wzfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yb9 SOLUTE CARRIER
FAMILY 2,
FACILITATED GLUCOSE
TRANSPORTER MEMBER 5

(Bos taurus) 		PF00083
(Sugar_tr) 		4 GLY D  85
GLY D  82
GLY D 136
GLY D 140
 None
 0.63A 3bogD-4yb9D:
undetectable		 3bogD-4yb9D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ybq SOLUTE CARRIER
FAMILY 2,
FACILITATED GLUCOSE
TRANSPORTER MEMBER 5

(Rattus
norvegicus) 		PF00083
(Sugar_tr) 		4 GLY A  84
GLY A  81
GLY A 135
GLY A 139
 None
 0.62A 3bogD-4ybqA:
undetectable		 3bogD-4ybqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c65 SOLUTE CARRIER
FAMILY 2,
FACILITATED GLUCOSE
TRANSPORTER MEMBER 3

(Homo sapiens) 		PF00083
(Sugar_tr) 		4 GLY A  77
GLY A  74
GLY A 128
GLY A 132
 None
 0.64A 3bogD-5c65A:
undetectable		 3bogD-5c65A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eqi SOLUTE CARRIER
FAMILY 2,
FACILITATED GLUCOSE
TRANSPORTER MEMBER 1

(Homo sapiens) 		PF00083
(Sugar_tr) 		4 GLY A  79
GLY A  76
GLY A 130
GLY A 134
 None
 0.67A 3bogD-5eqiA:
undetectable		 3bogD-5eqiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gwn PROTEIN RCC2

(Homo sapiens) 		PF00415
(RCC1) 		4 GLY A 465
GLY A 463
GLY A 460
GLY A 138
 None
 0.60A 3bogD-5gwnA:
undetectable		 3bogD-5gwnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j44 SERINE PROTEASE SEPA
AUTOTRANSPORTER

(Shigella
flexneri) 		PF02395
(Peptidase_S6) 		4 GLY A 326
GLY A 303
GLY A 294
GLY A 324
 None
 0.61A 3bogD-5j44A:
undetectable		 3bogD-5j44A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN

(Methanocaldococcus
jannaschii) 		PF00814
(Peptidase_M22) 		4 GLY A   5
GLY A 286
GLY A  14
GLY A  16
 None
 0.59A 3bogD-5jmvA:
undetectable		 3bogD-5jmvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m04 GTPASE OBGE/CGTA

(Escherichia
coli) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  16
GLY A  42
GLY A  14
GLY A  70
 None
 0.60A 3bogD-5m04A:
undetectable		 3bogD-5m04A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m04 GTPASE OBGE/CGTA

(Escherichia
coli) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  42
GLY A  70
GLY A  40
GLY A  83
 None
 0.65A 3bogD-5m04A:
undetectable		 3bogD-5m04A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m04 GTPASE OBGE/CGTA

(Escherichia
coli) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  70
GLY A  42
GLY A  14
GLY A  83
 None
 0.64A 3bogD-5m04A:
undetectable		 3bogD-5m04A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m04 GTPASE OBGE/CGTA

(Escherichia
coli) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  73
GLY A  39
GLY A  17
GLY A  80
 None
 0.64A 3bogD-5m04A:
undetectable		 3bogD-5m04A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI

(Synechocystis
sp. PCC 6803) 		no annotation 4 GLY 0 134
GLY 0 131
GLY 0  54
GLY 0  58
 BCR  0 205 ( 4.0A)
None
None
None
 0.64A 3bogD-5oy00:
undetectable		 3bogD-5oy00:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xvh 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
NAD-BINDING PROTEIN

(Pyrobaculum
calidifontis) 		no annotation 4 GLY A 164
GLY A 137
GLY A 161
GLY A 166
 None
 0.53A 3bogD-5xvhA:
undetectable		 3bogD-5xvhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y8p PROBABLE
3-HYDROXYISOBUTYRATE
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		no annotation 4 GLY A 162
GLY A 135
GLY A 159
GLY A 164
 None
 0.54A 3bogD-5y8pA:
undetectable		 3bogD-5y8pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 117
GLY D 155
GLY D 208
GLY D 154
 None
 0.64A 3bogD-6f45D:
undetectable		 3bogD-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 152
GLY D 116
GLY D 171
GLY D 129
 None
 0.64A 3bogD-6f45D:
undetectable		 3bogD-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 154
GLY D 129
GLY D 152
GLY D 117
 None
 0.60A 3bogD-6f45D:
undetectable		 3bogD-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 156
GLY D 208
GLY D 171
GLY D 215
 None
 0.63A 3bogD-6f45D:
undetectable		 3bogD-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 157
GLY D 126
GLY D 155
GLY D 120
 None
 0.55A 3bogD-6f45D:
undetectable		 3bogD-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 157
GLY D 224
GLY D 215
GLY D 126
 None
 0.65A 3bogD-6f45D:
undetectable		 3bogD-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 169
GLY D 186
GLY D 167
GLY D 177
 None
 0.66A 3bogD-6f45D:
undetectable		 3bogD-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 170
GLY D 177
GLY D 186
GLY D 119
 None
 0.63A 3bogD-6f45D:
undetectable		 3bogD-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 175
GLY D 170
GLY D 195
GLY D 171
 None
 0.66A 3bogD-6f45D:
undetectable		 3bogD-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 186
GLY D 169
GLY D 195
GLY D 177
 None
 0.60A 3bogD-6f45D:
undetectable		 3bogD-6f45D:
undetectable