SIMILAR PATTERNS OF AMINO ACIDS FOR 3BOG_C_DVAC47

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h5o MYOTOXIN

(Crotalus
durissus) 		PF00819
(Myotoxins) 		4 GLY A  40
GLY A   8
GLY A   9
GLY A  42
 None
 0.62A 3bogC-1h5oA:
0.0		 3bogC-1h5oA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  12
GLY A 119
GLY A  41
GLY A 146
 None
 0.62A 3bogC-1lnzA:
0.0		 3bogC-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  15
GLY A  13
GLY A  42
GLY A 120
 None
 0.67A 3bogC-1lnzA:
0.0		 3bogC-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  15
GLY A 122
GLY A  38
GLY A 143
 None
 0.61A 3bogC-1lnzA:
0.0		 3bogC-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  18
GLY A  38
GLY A  16
GLY A  72
 None
 0.58A 3bogC-1lnzA:
0.0		 3bogC-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  38
GLY A  16
GLY A  69
GLY A 122
 None
 0.66A 3bogC-1lnzA:
0.0		 3bogC-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  38
GLY A  72
GLY A  36
GLY A  79
 None
 0.60A 3bogC-1lnzA:
0.0		 3bogC-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgj 6-PHOSPHOGLUCONATE
DEHYDROGENASE

(Trypanosoma
brucei) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 GLY A 179
GLY A 145
GLY A 176
GLY A 181
 None
 0.60A 3bogC-1pgjA:
0.0		 3bogC-1pgjA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1)
PF09269
(DUF1967) 		4 GLY A  15
GLY A  41
GLY A  13
GLY A  68
 None
 0.63A 3bogC-1udxA:
0.0		 3bogC-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1)
PF09269
(DUF1967) 		4 GLY A  15
GLY A 121
GLY A  38
GLY A 142
 None
 0.58A 3bogC-1udxA:
0.0		 3bogC-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1)
PF09269
(DUF1967) 		4 GLY A  18
GLY A  38
GLY A  16
GLY A  71
 None
 0.66A 3bogC-1udxA:
0.0		 3bogC-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1)
PF09269
(DUF1967) 		4 GLY A  41
GLY A  68
GLY A  39
GLY A  81
 None
 0.66A 3bogC-1udxA:
0.0		 3bogC-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1)
PF09269
(DUF1967) 		4 GLY A  68
GLY A  41
GLY A  13
GLY A  81
 None
 0.65A 3bogC-1udxA:
0.0		 3bogC-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vpd TARTRONATE
SEMIALDEHYDE
REDUCTASE

(Salmonella
enterica) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 GLY A 166
GLY A 139
GLY A 163
GLY A 168
 None
 0.56A 3bogC-1vpdA:
undetectable		 3bogC-1vpdA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wv2 THIAZOLE
BIOSYNTHESIS PROTEIN
THIG

(Pseudomonas
aeruginosa) 		PF05690
(ThiG) 		4 GLY A1168
GLY A1195
GLY A1165
GLY A1170
 None
 0.58A 3bogC-1wv2A:
0.0		 3bogC-1wv2A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yb4 TARTRONIC
SEMIALDEHYDE
REDUCTASE

(Salmonella
enterica) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 GLY A 163
GLY A 136
GLY A 160
GLY A 165
 None
 0.57A 3bogC-1yb4A:
0.0		 3bogC-1yb4A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c7z 3-KETOACYL-COA
THIOLASE 2

(Arabidopsis
thaliana) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 GLY A 141
GLY A 103
GLY A 164
GLY A 396
 None
 0.58A 3bogC-2c7zA:
0.0		 3bogC-2c7zA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cvz 3-HYDROXYISOBUTYRATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 GLY A 159
GLY A 133
GLY A 156
GLY A 161
 None
 0.55A 3bogC-2cvzA:
undetectable		 3bogC-2cvzA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fx5 LIPASE

(Pseudomonas
mendocina) 		no annotation 4 GLY A  88
GLY A 128
GLY A  55
GLY A 131
 None
 0.67A 3bogC-2fx5A:
undetectable		 3bogC-2fx5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gf2 3-HYDROXYISOBUTYRATE
DEHYDROGENASE

(Homo sapiens) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 GLY A 203
GLY A 176
GLY A 200
GLY A 205
 None
 0.58A 3bogC-2gf2A:
undetectable		 3bogC-2gf2A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ivp O-SIALOGLYCOPROTEIN
ENDOPEPTIDASE

(Pyrococcus
abyssi) 		PF00814
(Peptidase_M22) 		4 GLY A   5
GLY A 287
GLY A  14
GLY A  16
 None
 0.59A 3bogC-2ivpA:
undetectable		 3bogC-2ivpA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iyo 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING

(Lactococcus
lactis) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 GLY A 178
GLY A 143
GLY A 175
GLY A 180
 None
 0.63A 3bogC-2iyoA:
undetectable		 3bogC-2iyoA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j6d CONKUNITZIN-S2

(Conus striatus) 		PF00014
(Kunitz_BPTI) 		4 GLY A  19
GLY A  17
GLY A  44
GLY A  42
 None
 0.60A 3bogC-2j6dA:
undetectable		 3bogC-2j6dA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jf7 STRICTOSIDINE-O-BETA
-D-GLUCOSIDASE

(Rauvolfia
serpentina) 		PF00232
(Glyco_hydro_1) 		4 GLY A 215
GLY A 219
GLY A 226
GLY A 224
 None
 0.57A 3bogC-2jf7A:
undetectable		 3bogC-2jf7A:
9.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  18
GLY A  36
GLY A  46
GLY A   9
 None
 0.64A 3bogC-2pneA:
18.3		 3bogC-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  21
GLY A  33
GLY A  49
GLY A   6
 None
 0.67A 3bogC-2pneA:
18.3		 3bogC-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  30
GLY A  52
GLY A  21
GLY A  61
 None
 0.65A 3bogC-2pneA:
18.3		 3bogC-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  33
GLY A  21
GLY A  31
GLY A   6
 None
 0.66A 3bogC-2pneA:
18.3		 3bogC-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  33
GLY A  51
GLY A  61
GLY A  21
 None
 0.63A 3bogC-2pneA:
18.3		 3bogC-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  36
GLY A  18
GLY A  34
GLY A   9
 None
 0.64A 3bogC-2pneA:
18.3		 3bogC-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  36
GLY A  48
GLY A  64
GLY A  18
 None
 0.64A 3bogC-2pneA:
18.3		 3bogC-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  39
GLY A  45
GLY A  67
GLY A  15
 None
 0.65A 3bogC-2pneA:
18.3		 3bogC-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  48
GLY A  36
GLY A  46
GLY A  18
 None
 0.64A 3bogC-2pneA:
18.3		 3bogC-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  48
GLY A  66
GLY A  73
GLY A  36
 None
 0.62A 3bogC-2pneA:
18.3		 3bogC-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  51
GLY A  33
GLY A  49
GLY A  21
 None
 0.66A 3bogC-2pneA:
18.3		 3bogC-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  51
GLY A  63
GLY A  76
GLY A  33
 None
 0.62A 3bogC-2pneA:
18.3		 3bogC-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  63
GLY A  51
GLY A  61
GLY A  33
 None
 0.65A 3bogC-2pneA:
18.3		 3bogC-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  66
GLY A  48
GLY A  64
GLY A  36
 None
 0.64A 3bogC-2pneA:
18.3		 3bogC-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  67
GLY A  45
GLY A  69
GLY A  73
 None
 0.65A 3bogC-2pneA:
18.3		 3bogC-2pneA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pne 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  69
GLY A  45
GLY A  67
GLY A  39
 None
 0.66A 3bogC-2pneA:
18.3		 3bogC-2pneA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uv8 FATTY ACID SYNTHASE
SUBUNIT BETA (FAS1)

(Saccharomyces
cerevisiae) 		PF00698
(Acyl_transf_1)
PF01575
(MaoC_dehydratas)
PF08354
(DUF1729)
PF13452
(MaoC_dehydrat_N)
PF16073
(SAT) 		4 GLY G1247
GLY G1104
GLY G1105
GLY G 588
 None
 0.67A 3bogC-2uv8G:
undetectable		 3bogC-2uv8G:
4.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vwb PUTATIVE
O-SIALOGLYCOPROTEIN
ENDOPEPTIDASE

(Methanocaldococcus
jannaschii) 		PF00814
(Peptidase_M22)
PF01163
(RIO1) 		4 GLY A   5
GLY A 286
GLY A  14
GLY A  16
 None
 0.65A 3bogC-2vwbA:
undetectable		 3bogC-2vwbA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w8z 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING

(Geobacillus
stearothermophilus) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 GLY A 176
GLY A 143
GLY A 173
GLY A 178
 None
 0.62A 3bogC-2w8zA:
undetectable		 3bogC-2w8zA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wua ACETOACETYL COA
THIOLASE

(Helianthus
annuus) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 GLY A 394
GLY A 139
GLY A 397
GLY A 162
 None
 0.67A 3bogC-2wuaA:
undetectable		 3bogC-2wuaA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyg 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING

(Klebsiella
pneumoniae) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 GLY A 177
GLY A 143
GLY A 174
GLY A 179
 None
 0.60A 3bogC-2zygA:
undetectable		 3bogC-2zygA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ak5 HEMOGLOBIN-BINDING
PROTEASE HBP

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		4 GLY A 378
GLY A 355
GLY A 346
GLY A 376
 None
 0.61A 3bogC-3ak5A:
undetectable		 3bogC-3ak5A:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b59 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE

(Novosphingobium
aromaticivorans) 		PF00903
(Glyoxalase) 		4 GLY A 226
GLY A 282
GLY A 283
GLY A 224
 None
 0.67A 3bogC-3b59A:
undetectable		 3bogC-3b59A:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus) 		PF03069
(FmdA_AmdA) 		4 GLY A 156
GLY A 154
GLY A 145
GLY A 143
 None
 0.64A 3bogC-3b9tA:
undetectable		 3bogC-3b9tA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  30
GLY A  52
GLY A  21
GLY A  61
 None
 0.65A 3bogC-3bogA:
19.3		 3bogC-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  33
GLY A  21
GLY A  31
GLY A   6
 None
 0.65A 3bogC-3bogA:
19.3		 3bogC-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  33
GLY A  51
GLY A  61
GLY A  21
 None
 0.59A 3bogC-3bogA:
19.3		 3bogC-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  36
GLY A  18
GLY A  34
GLY A   9
 None
 0.52A 3bogC-3bogA:
19.3		 3bogC-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  36
GLY A  48
GLY A  64
GLY A  18
 None
 0.63A 3bogC-3bogA:
19.3		 3bogC-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  39
GLY A  45
GLY A  67
GLY A  15
 None
None
None
SYS  A  11 ( 4.3A)
 0.66A 3bogC-3bogA:
19.3		 3bogC-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  48
GLY A  36
GLY A  46
GLY A  18
 None
 0.61A 3bogC-3bogA:
19.3		 3bogC-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  48
GLY A  66
GLY A  73
GLY A  36
 None
 0.62A 3bogC-3bogA:
19.3		 3bogC-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  51
GLY A  63
GLY A  76
GLY A  33
 None
 0.67A 3bogC-3bogA:
19.3		 3bogC-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  63
GLY A  51
GLY A  61
GLY A  33
 None
 0.58A 3bogC-3bogA:
19.3		 3bogC-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  66
GLY A  48
GLY A  64
GLY A  36
 None
 0.66A 3bogC-3bogA:
19.3		 3bogC-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bog 6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN

(Hypogastrura
harveyi) 		no annotation 4 GLY A  67
GLY A  45
GLY A  69
GLY A  73
 None
 0.66A 3bogC-3bogA:
19.3		 3bogC-3bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cky 2-HYDROXYMETHYL
GLUTARATE
DEHYDROGENASE

(Eubacterium
barkeri) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 GLY A 168
GLY A 141
GLY A 165
GLY A 170
 None
 0.52A 3bogC-3ckyA:
undetectable		 3bogC-3ckyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e73 LANC-LIKE PROTEIN 1

(Homo sapiens) 		PF05147
(LANC_like) 		4 GLY A  67
GLY A  64
GLY A  59
GLY A  61
 None
 0.67A 3bogC-3e73A:
undetectable		 3bogC-3e73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fsr NADP-DEPENDENT
ALCOHOL
DEHYDROGENASE

(Clostridium
beijerinckii;
Thermoanaerobacter
brockii) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 GLY A 176
GLY A 174
GLY A 243
GLY A 179
 None
 0.65A 3bogC-3fsrA:
undetectable		 3bogC-3fsrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3me1 UREA TRANSPORTER

(Desulfovibrio
vulgaris) 		PF03253
(UT) 		4 GLY A 107
GLY A  55
GLY A  86
GLY A  82
 None
 0.59A 3bogC-3me1A:
undetectable		 3bogC-3me1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q3c PROBABLE
3-HYDROXYISOBUTYRATE
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 GLY A 165
GLY A 138
GLY A 162
GLY A 167
 None
 0.49A 3bogC-3q3cA:
undetectable		 3bogC-3q3cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qha PUTATIVE
OXIDOREDUCTASE

(Mycobacterium
avium) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 GLY A 171
GLY A 144
GLY A 168
GLY A 173
 None
 0.54A 3bogC-3qhaA:
undetectable		 3bogC-3qhaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u5u RAUCAFFRICINE-O-BETA
-D-GLUCOSIDASE

(Rauvolfia
serpentina) 		PF00232
(Glyco_hydro_1) 		4 GLY A 194
GLY A 198
GLY A 205
GLY A 203
 None
 0.59A 3bogC-3u5uA:
undetectable		 3bogC-3u5uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ugv ENOLASE

(alpha
proteobacterium
BAL199) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 GLY A 342
GLY A 166
GLY A 164
GLY A 162
 None
 0.53A 3bogC-3ugvA:
undetectable		 3bogC-3ugvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c2k 3-KETOACYL-COA
THIOLASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 GLY A 355
GLY A  95
GLY A 358
GLY A 118
 None
 0.67A 3bogC-4c2kA:
undetectable		 3bogC-4c2kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dll 2-HYDROXY-3-OXOPROPI
ONATE REDUCTASE

(Polaromonas sp.
JS666) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 GLY A 193
GLY A 167
GLY A 190
GLY A 195
 None
 0.57A 3bogC-4dllA:
undetectable		 3bogC-4dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e21 6-PHOSPHOGLUCONATE
DEHYDROGENASE
(DECARBOXYLATING)

(Geobacter
metallireducens) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 GLY A 182
GLY A 135
GLY A 179
GLY A 184
 None
 0.60A 3bogC-4e21A:
undetectable		 3bogC-4e21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jrm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Vibrio cholerae) 		no annotation 4 GLY D 167
GLY D 190
GLY D 106
GLY D 189
 None
 0.66A 3bogC-4jrmD:
undetectable		 3bogC-4jrmD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nwz FAD-DEPENDENT
PYRIDINE
NUCLEOTIDE-DISULFIDE
OXIDOREDUCTASE

(Caldalkalibacillus
thermarum) 		PF07992
(Pyr_redox_2) 		4 GLY A  12
GLY A  10
GLY A 106
GLY A  15
 FAD  A 601 (-3.3A)
FAD  A 601 ( 3.7A)
None
None
 0.66A 3bogC-4nwzA:
undetectable		 3bogC-4nwzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r8e 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Yersinia pestis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 GLY A 343
GLY A 189
GLY A 105
GLY A 166
 None
 0.65A 3bogC-4r8eA:
undetectable		 3bogC-4r8eA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y67 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE,
APICOPLAST

(Plasmodium
falciparum) 		PF02670
(DXP_reductoisom)
PF08436
(DXP_redisom_C)
PF13288
(DXPR_C) 		4 GLY A  87
GLY A  84
GLY A 180
GLY A  90
 None
 0.67A 3bogC-4y67A:
undetectable		 3bogC-4y67A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ybq SOLUTE CARRIER
FAMILY 2,
FACILITATED GLUCOSE
TRANSPORTER MEMBER 5

(Rattus
norvegicus) 		PF00083
(Sugar_tr) 		4 GLY A  84
GLY A  81
GLY A 135
GLY A 139
 None
 0.67A 3bogC-4ybqA:
undetectable		 3bogC-4ybqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gwn PROTEIN RCC2

(Homo sapiens) 		PF00415
(RCC1) 		4 GLY A 465
GLY A 463
GLY A 460
GLY A 138
 None
 0.67A 3bogC-5gwnA:
undetectable		 3bogC-5gwnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j44 SERINE PROTEASE SEPA
AUTOTRANSPORTER

(Shigella
flexneri) 		PF02395
(Peptidase_S6) 		4 GLY A 326
GLY A 303
GLY A 294
GLY A 324
 None
 0.53A 3bogC-5j44A:
undetectable		 3bogC-5j44A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jcn OS09G0567300 PROTEIN

(Oryza sativa) 		PF07992
(Pyr_redox_2) 		4 GLY A 173
GLY A 171
GLY A 259
GLY A 176
 NAD  A 501 (-3.5A)
NAD  A 501 ( 3.8A)
NAD  A 501 (-3.2A)
None
 0.67A 3bogC-5jcnA:
undetectable		 3bogC-5jcnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN

(Methanocaldococcus
jannaschii) 		PF00814
(Peptidase_M22) 		4 GLY A   5
GLY A 286
GLY A  14
GLY A  16
 None
 0.64A 3bogC-5jmvA:
undetectable		 3bogC-5jmvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE DELTA
SUBUNIT

(Aromatoleum
aromaticum) 		PF02538
(Hydantoinase_B) 		4 GLY A 471
GLY A 585
GLY A 473
GLY A 477
 None
 0.65A 3bogC-5l9wA:
undetectable		 3bogC-5l9wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE DELTA
SUBUNIT

(Aromatoleum
aromaticum) 		PF02538
(Hydantoinase_B) 		4 GLY A 477
GLY A 583
GLY A 582
GLY A 471
 None
 0.63A 3bogC-5l9wA:
undetectable		 3bogC-5l9wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m04 GTPASE OBGE/CGTA

(Escherichia
coli) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  16
GLY A  42
GLY A  14
GLY A  70
 None
 0.56A 3bogC-5m04A:
undetectable		 3bogC-5m04A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m04 GTPASE OBGE/CGTA

(Escherichia
coli) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  42
GLY A  70
GLY A  40
GLY A  83
 None
 0.64A 3bogC-5m04A:
undetectable		 3bogC-5m04A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m04 GTPASE OBGE/CGTA

(Escherichia
coli) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  70
GLY A  42
GLY A  14
GLY A  83
 None
 0.62A 3bogC-5m04A:
undetectable		 3bogC-5m04A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m04 GTPASE OBGE/CGTA

(Escherichia
coli) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A  73
GLY A  39
GLY A  17
GLY A  80
 None
 0.65A 3bogC-5m04A:
undetectable		 3bogC-5m04A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI

(Synechocystis
sp. PCC 6803) 		no annotation 4 GLY 0 134
GLY 0 131
GLY 0  54
GLY 0  58
 BCR  0 205 ( 4.0A)
None
None
None
 0.66A 3bogC-5oy00:
undetectable		 3bogC-5oy00:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xvh 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
NAD-BINDING PROTEIN

(Pyrobaculum
calidifontis) 		no annotation 4 GLY A 164
GLY A 137
GLY A 161
GLY A 166
 None
 0.55A 3bogC-5xvhA:
undetectable		 3bogC-5xvhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y8p PROBABLE
3-HYDROXYISOBUTYRATE
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		no annotation 4 GLY A 162
GLY A 135
GLY A 159
GLY A 164
 None
 0.55A 3bogC-5y8pA:
undetectable		 3bogC-5y8pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 152
GLY D 116
GLY D 171
GLY D 129
 None
 0.57A 3bogC-6f45D:
undetectable		 3bogC-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 154
GLY D 129
GLY D 152
GLY D 117
 None
 0.60A 3bogC-6f45D:
undetectable		 3bogC-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 155
GLY D 119
GLY D 168
GLY D 126
 None
 0.63A 3bogC-6f45D:
undetectable		 3bogC-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 155
GLY D 171
GLY D 153
GLY D 208
 None
 0.67A 3bogC-6f45D:
undetectable		 3bogC-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 156
GLY D 208
GLY D 171
GLY D 215
 None
 0.59A 3bogC-6f45D:
undetectable		 3bogC-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 157
GLY D 126
GLY D 155
GLY D 120
 None
 0.57A 3bogC-6f45D:
undetectable		 3bogC-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 157
GLY D 224
GLY D 215
GLY D 126
 None
 0.62A 3bogC-6f45D:
undetectable		 3bogC-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 169
GLY D 186
GLY D 167
GLY D 177
 None
 0.66A 3bogC-6f45D:
undetectable		 3bogC-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 170
GLY D 177
GLY D 186
GLY D 119
 None
 0.60A 3bogC-6f45D:
undetectable		 3bogC-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 186
GLY D 169
GLY D 195
GLY D 177
 None
 0.59A 3bogC-6f45D:
undetectable		 3bogC-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 GLY D 215
GLY D 156
GLY D 206
GLY D 224
 None
 0.66A 3bogC-6f45D:
undetectable		 3bogC-6f45D:
undetectable