SIMILAR PATTERNS OF AMINO ACIDS FOR 3BOG_C_DVAC10

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aj6 GYRASE

(Escherichia
coli)
PF02518
(HATPase_c)
3 GLY A 113
GLY A  35
GLY A  28
None
0.42A 3bogC-1aj6A:
0.0
3bogC-1aj6A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aj6 GYRASE

(Escherichia
coli)
PF02518
(HATPase_c)
3 GLY A 114
GLY A  24
GLY A  28
None
0.42A 3bogC-1aj6A:
0.0
3bogC-1aj6A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b3q PROTEIN (CHEMOTAXIS
PROTEIN CHEA)


(Thermotoga
maritima)
PF01584
(CheW)
PF02518
(HATPase_c)
PF02895
(H-kinase_dim)
3 GLY A 414
GLY A 530
GLY A 451
None
0.40A 3bogC-1b3qA:
0.0
3bogC-1b3qA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bw0 PROTEIN (TYROSINE
AMINOTRANSFERASE)


(Trypanosoma
cruzi)
PF00155
(Aminotran_1_2)
3 GLY A 112
GLY A 250
GLY A 263
LLP  A 253 ( 4.6A)
None
None
0.39A 3bogC-1bw0A:
0.0
3bogC-1bw0A:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dju AROMATIC
AMINOTRANSFERASE


(Pyrococcus
horikoshii)
PF00155
(Aminotran_1_2)
3 GLY A  95
GLY A 230
GLY A 243
PLP  A 400 (-3.2A)
None
PLP  A 400 ( 4.9A)
0.42A 3bogC-1djuA:
0.0
3bogC-1djuA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f0k UDP-N-ACETYLGLUCOSAM
INE-N-ACETYLMURAMYL-
(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE


(Escherichia
coli)
PF03033
(Glyco_transf_28)
PF04101
(Glyco_tran_28_C)
3 GLY A 220
GLY A 190
GLY A 194
None
0.42A 3bogC-1f0kA:
0.0
3bogC-1f0kA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gxk CHROMOSOME
SEGREGATION SMC
PROTEIN


(Thermotoga
maritima)
PF06470
(SMC_hinge)
3 GLY A 615
GLY A 578
GLY A 611
None
0.38A 3bogC-1gxkA:
0.0
3bogC-1gxkA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h2b ALCOHOL
DEHYDROGENASE


(Aeropyrum
pernix)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
3 GLY A 136
GLY A 130
GLY A  78
None
0.42A 3bogC-1h2bA:
0.0
3bogC-1h2bA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i5a CHEMOTAXIS PROTEIN
CHEA


(Thermotoga
maritima)
PF02518
(HATPase_c)
3 GLY A 414
GLY A 530
GLY A 451
ACP  A 998 (-3.4A)
None
None
0.34A 3bogC-1i5aA:
0.0
3bogC-1i5aA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l1l RIBONUCLEOSIDE
TRIPHOSPHATE
REDUCTASE


(Lactobacillus
leichmannii)
PF02867
(Ribonuc_red_lgC)
3 GLY A  27
GLY A 558
GLY A  24
None
0.43A 3bogC-1l1lA:
0.0
3bogC-1l1lA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l8f ENDOGLUCANASE

(Melanocarpus
albomyces)
PF02015
(Glyco_hydro_45)
3 GLY A 127
GLY A 143
GLY A 148
None
0.31A 3bogC-1l8fA:
undetectable
3bogC-1l8fA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ldi GLYCEROL UPTAKE
FACILITATOR PROTEIN


(Escherichia
coli)
PF00230
(MIP)
3 GLY A 191
GLY A 199
GLY A 195
None
0.41A 3bogC-1ldiA:
undetectable
3bogC-1ldiA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lrw METHANOL
DEHYDROGENASE
SUBUNIT 1


(Paracoccus
denitrificans)
PF01011
(PQQ)
PF13360
(PQQ_2)
3 GLY A 518
GLY A 396
GLY A 477
None
0.43A 3bogC-1lrwA:
undetectable
3bogC-1lrwA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mwo ALPHA AMYLASE

(Pyrococcus
woesei)
PF00128
(Alpha-amylase)
PF09154
(DUF1939)
3 GLY A 363
GLY A 339
GLY A 357
None
0.41A 3bogC-1mwoA:
undetectable
3bogC-1mwoA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o4s ASPARTATE
AMINOTRANSFERASE


(Thermotoga
maritima)
PF00155
(Aminotran_1_2)
3 GLY A  97
GLY A 231
GLY A 244
PLP  A1234 (-3.4A)
None
None
0.43A 3bogC-1o4sA:
undetectable
3bogC-1o4sA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o8c YHDH

(Escherichia
coli)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
3 GLY A  97
GLY A  91
GLY A  62
None
0.40A 3bogC-1o8cA:
undetectable
3bogC-1o8cA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rjw ALCOHOL
DEHYDROGENASE


(Geobacillus
stearothermophilus)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
3 GLY A 119
GLY A 113
GLY A  60
None
0.41A 3bogC-1rjwA:
undetectable
3bogC-1rjwA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t5b ACYL CARRIER PROTEIN
PHOSPHODIESTERASE


(Salmonella
enterica)
PF02525
(Flavodoxin_2)
3 GLY A 128
GLY A 162
GLY A 165
None
0.39A 3bogC-1t5bA:
undetectable
3bogC-1t5bA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t5o TRANSLATION
INITIATION FACTOR
EIF2B, SUBUNIT DELTA


(Archaeoglobus
fulgidus)
PF01008
(IF-2B)
3 GLY A 157
GLY A 169
GLY A 165
None
0.40A 3bogC-1t5oA:
undetectable
3bogC-1t5oA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1thg LIPASE 2

(Galactomyces
candidus)
PF00135
(COesterase)
3 GLY A 215
GLY A 130
GLY A 219
None
0.43A 3bogC-1thgA:
undetectable
3bogC-1thgA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tt7 YHFP

(Bacillus
subtilis)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
3 GLY A 101
GLY A  95
GLY A  66
None
0.38A 3bogC-1tt7A:
undetectable
3bogC-1tt7A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1udx THE GTP-BINDING
PROTEIN OBG


(Thermus
thermophilus)
PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1)
PF09269
(DUF1967)
3 GLY A 145
GLY A  41
GLY A  13
None
0.43A 3bogC-1udxA:
undetectable
3bogC-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w2w 5-METHYLTHIORIBOSE-1
-PHOSPHATE ISOMERASE


(Saccharomyces
cerevisiae)
PF01008
(IF-2B)
3 GLY A 184
GLY A 196
GLY A 192
None
0.40A 3bogC-1w2wA:
undetectable
3bogC-1w2wA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w6s METHANOL
DEHYDROGENASE
SUBUNIT 1


(Methylobacterium
extorquens)
PF01011
(PQQ)
PF13360
(PQQ_2)
3 GLY A 518
GLY A 396
GLY A 477
None
0.42A 3bogC-1w6sA:
undetectable
3bogC-1w6sA:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xa0 PUTATIVE NADPH
DEPENDENT
OXIDOREDUCTASES


(Geobacillus
stearothermophilus)
PF00107
(ADH_zinc_N)
3 GLY A 100
GLY A  94
GLY A  65
None
0.43A 3bogC-1xa0A:
undetectable
3bogC-1xa0A:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yle ARGININE
N-SUCCINYLTRANSFERAS
E, ALPHA CHAIN


(Pseudomonas
aeruginosa)
PF04958
(AstA)
3 GLY A 166
GLY A 227
GLY A 257
None
0.42A 3bogC-1yleA:
undetectable
3bogC-1yleA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zc6 PROBABLE
N-ACETYLGLUCOSAMINE
KINASE


(Chromobacterium
violaceum)
PF01869
(BcrAD_BadFG)
3 GLY A 281
GLY A 286
GLY A 117
None
0.43A 3bogC-1zc6A:
undetectable
3bogC-1zc6A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zc6 PROBABLE
N-ACETYLGLUCOSAMINE
KINASE


(Chromobacterium
violaceum)
PF01869
(BcrAD_BadFG)
3 GLY A 286
GLY A 120
GLY A 117
None
0.41A 3bogC-1zc6A:
undetectable
3bogC-1zc6A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b0t NADP ISOCITRATE
DEHYDROGENASE


(Corynebacterium
glutamicum)
PF03971
(IDH)
3 GLY A 294
GLY A 266
GLY A 291
None
0.38A 3bogC-2b0tA:
undetectable
3bogC-2b0tA:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bvg 6-HYDROXY-D-NICOTINE
OXIDASE


(Paenarthrobacter
nicotinovorans)
PF01565
(FAD_binding_4)
PF08031
(BBE)
3 GLY A 137
GLY A  70
GLY A 134
FAD  A 600 (-2.9A)
FAD  A 600 (-2.9A)
FAD  A 600 (-3.7A)
0.42A 3bogC-2bvgA:
undetectable
3bogC-2bvgA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d0v METHANOL
DEHYDROGENASE LARGE
SUBUNIT


(Hyphomicrobium
denitrificans)
PF01011
(PQQ)
PF13360
(PQQ_2)
3 GLY A 518
GLY A 396
GLY A 477
None
0.43A 3bogC-2d0vA:
undetectable
3bogC-2d0vA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d3l GLUCAN
1,4-ALPHA-MALTOHEXAO
SIDASE


(Bacillus sp.
707)
PF00128
(Alpha-amylase)
PF09154
(DUF1939)
3 GLY A 425
GLY A 399
GLY A 417
None
0.42A 3bogC-2d3lA:
undetectable
3bogC-2d3lA:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d5i AZO REDUCTASE

(Escherichia
coli)
PF02525
(Flavodoxin_2)
3 GLY A 127
GLY A 161
GLY A 164
None
0.41A 3bogC-2d5iA:
undetectable
3bogC-2d5iA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ejv L-THREONINE
3-DEHYDROGENASE


(Thermus
thermophilus)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
3 GLY A 120
GLY A 114
GLY A  62
None
0.43A 3bogC-2ejvA:
undetectable
3bogC-2ejvA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eng ENDOGLUCANASE V

(Humicola
insolens)
PF02015
(Glyco_hydro_45)
3 GLY A 128
GLY A 144
GLY A 149
None
0.34A 3bogC-2engA:
undetectable
3bogC-2engA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2


(Staphylococcus
aureus)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
3 GLY A 190
GLY A 347
GLY A 168
None
0.43A 3bogC-2gqdA:
undetectable
3bogC-2gqdA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iwa GLUTAMINE
CYCLOTRANSFERASE


(Carica papaya)
PF05096
(Glu_cyclase_2)
3 GLY A 133
GLY A  47
GLY A  92
None
0.42A 3bogC-2iwaA:
undetectable
3bogC-2iwaA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oua SERINE PROTEASE

(Nocardiopsis
alba)
PF00089
(Trypsin)
3 GLY A 197
GLY A  18
GLY A  44
None
0.44A 3bogC-2ouaA:
undetectable
3bogC-2ouaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfe ALKALINE SERINE
PROTEASE


(Thermobifida
fusca)
PF00089
(Trypsin)
3 GLY A 197
GLY A  18
GLY A  44
None
0.41A 3bogC-2pfeA:
undetectable
3bogC-2pfeA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qq6 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN


(Rubrobacter
xylanophilus)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
3 GLY A 105
GLY A 374
GLY A 101
None
0.42A 3bogC-2qq6A:
undetectable
3bogC-2qq6A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rdy BH0842 PROTEIN

(Bacillus
halodurans)
PF14498
(Glyco_hyd_65N_2)
3 GLY A 157
GLY A 225
GLY A 238
None
0.37A 3bogC-2rdyA:
undetectable
3bogC-2rdyA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2sfa SERINE PROTEINASE

(Streptomyces
fradiae)
PF00089
(Trypsin)
3 GLY A 149
GLY A   3
GLY A  18
None
0.37A 3bogC-2sfaA:
undetectable
3bogC-2sfaA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wge 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 1


(Mycobacterium
tuberculosis)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
3 GLY A  62
GLY A 344
GLY A 240
None
0.42A 3bogC-2wgeA:
undetectable
3bogC-2wgeA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsj SULFITE REDUCTASE
BETA SUBUNIT


(Desulfomicrobium
norvegicum)
PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr)
PF12838
(Fer4_7)
3 GLY B 174
GLY B  50
GLY B 133
None
0.39A 3bogC-2xsjB:
undetectable
3bogC-2xsjB:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z61 PROBABLE ASPARTATE
AMINOTRANSFERASE 2


(Methanocaldococcus
jannaschii)
PF00155
(Aminotran_1_2)
3 GLY A  97
GLY A 219
GLY A 232
LLP  A 222 ( 3.8A)
None
None
0.44A 3bogC-2z61A:
undetectable
3bogC-2z61A:
8.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3act CELLOBIOSE
PHOSPHORYLASE


(Cellulomonas
gilvus)
PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36)
3 GLY A 681
GLY A 787
GLY A 762
None
0.36A 3bogC-3actA:
undetectable
3bogC-3actA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN


(Methylobacillus
flagellatus)
PF03069
(FmdA_AmdA)
3 GLY A 156
GLY A  85
GLY A 143
None
0.41A 3bogC-3b9tA:
undetectable
3bogC-3b9tA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bc9 ALPHA AMYLASE,
CATALYTIC REGION


(Halothermothrix
orenii)
PF00128
(Alpha-amylase)
PF09154
(DUF1939)
3 GLY A 534
GLY A 507
GLY A 526
None
None
CA  A 705 ( 4.1A)
0.42A 3bogC-3bc9A:
undetectable
3bogC-3bc9A:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3biw NEUROLIGIN-1

(Rattus
norvegicus)
PF00135
(COesterase)
3 GLY A 279
GLY A 201
GLY A 283
None
0.43A 3bogC-3biwA:
undetectable
3bogC-3biwA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cio TYROSINE-PROTEIN
KINASE ETK


(Escherichia
coli)
PF13614
(AAA_31)
3 GLY A 674
GLY A 714
GLY A 452
None
0.40A 3bogC-3cioA:
undetectable
3bogC-3cioA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dh4 SODIUM/GLUCOSE
COTRANSPORTER


(Vibrio
parahaemolyticus)
PF00474
(SSF)
3 GLY A  81
GLY A 305
GLY A  77
None
0.35A 3bogC-3dh4A:
undetectable
3bogC-3dh4A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwk PENICILLIN-BINDING
PROTEIN 2


(Staphylococcus
aureus)
PF00905
(Transpeptidase)
PF00912
(Transgly)
3 GLY A 587
GLY A 497
GLY A 397
None
0.42A 3bogC-3dwkA:
undetectable
3bogC-3dwkA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1j ATP-DEPENDENT
PROTEASE LON


(Thermococcus
onnurineus)
PF01078
(Mg_chelatase)
PF05362
(Lon_C)
PF13654
(AAA_32)
3 GLY A 232
GLY A 205
GLY A 209
None
0.40A 3bogC-3k1jA:
undetectable
3bogC-3k1jA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lke ENOYL-COA HYDRATASE

(Bacillus
halodurans)
PF00378
(ECH_1)
3 GLY A 116
GLY A  27
GLY A  65
None
0.44A 3bogC-3lkeA:
undetectable
3bogC-3lkeA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING


(Brucella suis)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
3 GLY A 123
GLY A 117
GLY A  64
None
0.43A 3bogC-3meqA:
undetectable
3bogC-3meqA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nf4 ACYL-COA
DEHYDROGENASE


(Mycolicibacterium
thermoresistibile)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
3 GLY A  56
GLY A 123
GLY A  53
None
0.38A 3bogC-3nf4A:
undetectable
3bogC-3nf4A:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nok GLUTAMINYL CYCLASE

(Myxococcus
xanthus)
PF05096
(Glu_cyclase_2)
3 GLY A 128
GLY A  47
GLY A  88
None
0.36A 3bogC-3nokA:
undetectable
3bogC-3nokA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nom GLUTAMINE
CYCLOTRANSFERASE


(Zymomonas
mobilis)
PF05096
(Glu_cyclase_2)
3 GLY A 131
GLY A  47
GLY A  91
None
0.35A 3bogC-3nomA:
undetectable
3bogC-3nomA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nx4 PUTATIVE
OXIDOREDUCTASE


(Salmonella
enterica)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
3 GLY A  97
GLY A  91
GLY A  62
None
0.42A 3bogC-3nx4A:
undetectable
3bogC-3nx4A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pdi NITROGENASE MOFE
COFACTOR
BIOSYNTHESIS PROTEIN
NIFN


(Azotobacter
vinelandii)
PF00148
(Oxidored_nitro)
3 GLY B  30
GLY B 207
GLY B 225
None
0.43A 3bogC-3pdiB:
undetectable
3bogC-3pdiB:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pdx TYROSINE
AMINOTRANSFERASE


(Mus musculus)
PF00155
(Aminotran_1_2)
3 GLY A 143
GLY A 277
GLY A 290
LLP  A 280 ( 3.1A)
None
None
0.39A 3bogC-3pdxA:
undetectable
3bogC-3pdxA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qgv ALPHA AMYLASE

(Pyrococcus
woesei)
PF00128
(Alpha-amylase)
PF09154
(DUF1939)
3 GLY A 363
GLY A 339
GLY A 357
None
BCD  A 601 (-3.5A)
None
0.39A 3bogC-3qgvA:
undetectable
3bogC-3qgvA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY


(Cupriavidus
pinatubonensis)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
3 GLY A 123
GLY A 117
GLY A  64
None
0.44A 3bogC-3s2gA:
undetectable
3bogC-3s2gA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ure ALPHA-LYTIC PROTEASE

(Lysobacter
enzymogenes)
PF00089
(Trypsin)
3 GLY A 197
GLY A  18
GLY A  44
None
0.41A 3bogC-3ureA:
undetectable
3bogC-3ureA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w79 FMN-DEPENDENT
NADH-AZOREDUCTASE


(Bacillus sp.
B29)
PF02525
(Flavodoxin_2)
3 GLY A 134
GLY A 171
GLY A 174
None
0.39A 3bogC-3w79A:
undetectable
3bogC-3w79A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aah METHANOL
DEHYDROGENASE


(Methylophilus
methylotrophus)
PF13360
(PQQ_2)
3 GLY A 509
GLY A 389
GLY A 468
None
0.41A 3bogC-4aahA:
undetectable
3bogC-4aahA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cvq GLUTAMATE-PYRUVATE
AMINOTRANSFERASE
ALAA


(Escherichia
coli)
PF00155
(Aminotran_1_2)
3 GLY A 103
GLY A 237
GLY A 250
PLP  A1240 (-3.2A)
None
PLP  A1240 ( 4.9A)
0.43A 3bogC-4cvqA:
undetectable
3bogC-4cvqA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e9o IMV MEMBRANE PROTEIN

(Vaccinia virus)
PF00194
(Carb_anhydrase)
3 GLY X  89
GLY X  71
GLY X  77
None
0.44A 3bogC-4e9oX:
undetectable
3bogC-4e9oX:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4epa PESTICIN RECEPTOR

(Yersinia pestis)
PF00593
(TonB_dep_Rec)
PF07715
(Plug)
3 GLY A 432
GLY A 120
GLY A 116
None
0.43A 3bogC-4epaA:
undetectable
3bogC-4epaA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ese FMN-DEPENDENT
NADH-AZOREDUCTASE


(Yersinia pestis)
PF02525
(Flavodoxin_2)
3 GLY A 128
GLY A 162
GLY A 165
None
0.39A 3bogC-4eseA:
undetectable
3bogC-4eseA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE


(Homo sapiens)
PF13561
(adh_short_C2)
3 GLY A 179
GLY A 171
GLY A 168
None
0.39A 3bogC-4fc7A:
undetectable
3bogC-4fc7A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gkv ALCOHOL
DEHYDROGENASE,
PROPANOL-PREFERRING


(Escherichia
coli)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
3 GLY A 116
GLY A 110
GLY A  57
None
0.42A 3bogC-4gkvA:
undetectable
3bogC-4gkvA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i59 CYCLOHEXYLAMINE
OXIDASE


(Microbacterium
oxydans)
PF01593
(Amino_oxidase)
3 GLY A 371
GLY A 319
GLY A 201
None
0.44A 3bogC-4i59A:
undetectable
3bogC-4i59A:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iws PA0254

(Pseudomonas
aeruginosa)
PF01977
(UbiD)
3 GLY A 144
GLY A 287
GLY A 274
None
0.41A 3bogC-4iwsA:
undetectable
3bogC-4iwsA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l1f ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN


(Acidaminococcus
fermentans)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
3 GLY A  49
GLY A 117
GLY A  46
None
0.40A 3bogC-4l1fA:
undetectable
3bogC-4l1fA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgn CELLULOSE-BINDING,
FAMILY II


(Acidothermus
cellulolyticus)
no annotation 3 GLY A 453
GLY A 493
GLY A 476
None
0.41A 3bogC-4lgnA:
undetectable
3bogC-4lgnA:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lmh EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT OMCA


(Shewanella
oneidensis)
no annotation 3 GLY A 601
GLY A 663
GLY A 669
None
0.37A 3bogC-4lmhA:
undetectable
3bogC-4lmhA:
9.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mea PREDICTED PROTEIN

(Acinetobacter
nosocomialis)
PF00561
(Abhydrolase_1)
3 GLY A 237
GLY A 299
GLY A 328
None
0.34A 3bogC-4meaA:
undetectable
3bogC-4meaA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mm1 GERANYLGERANYLGLYCER
YL PHOSPHATE
SYNTHASE


(Methanothermobacter
thermautotrophicus)
PF01884
(PcrB)
3 GLY A 176
GLY A 140
GLY A 136
1GP  A 301 ( 4.2A)
None
None
0.38A 3bogC-4mm1A:
undetectable
3bogC-4mm1A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ru5 TAILSPIKE GP27

(Pseudomonas
phage phi297)
no annotation 3 GLY A 508
GLY A 538
GLY A 514
None
0.37A 3bogC-4ru5A:
undetectable
3bogC-4ru5A:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4twk POTASSIUM CHANNEL
SUBFAMILY K MEMBER 2


(Homo sapiens)
PF07885
(Ion_trans_2)
3 GLY A 253
GLY A 146
GLY A 255
K  A 402 ( 4.5A)
K  A 402 (-3.9A)
K  A 402 ( 4.2A)
0.37A 3bogC-4twkA:
undetectable
3bogC-4twkA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u9p UPF0264 PROTEIN
MJ1099


(Methanocaldococcus
jannaschii)
PF04476
(4HFCP_synth)
3 GLY A  32
GLY A  60
GLY A  35
None
0.33A 3bogC-4u9pA:
undetectable
3bogC-4u9pA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wrr PUTATIVE
DIACYLGLYCEROL
KINASE


(Bacillus
anthracis)
PF00781
(DAGK_cat)
3 GLY A 161
GLY A 206
GLY A 164
None
0.38A 3bogC-4wrrA:
undetectable
3bogC-4wrrA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zpx ATP-DEPENDENT
PROTEASE LON


(Thermococcus
onnurineus)
PF01078
(Mg_chelatase)
PF13654
(AAA_32)
3 GLY A 232
GLY A 205
GLY A 209
None
0.38A 3bogC-4zpxA:
undetectable
3bogC-4zpxA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a9q NUCLEOPORIN NUP43

(Homo sapiens)
PF00400
(WD40)
3 GLY 0 240
GLY 0 236
GLY 0 237
None
0.40A 3bogC-5a9q0:
undetectable
3bogC-5a9q0:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b69 GERANYLGERANYLGLYCER
YL PHOSPHATE
SYNTHASE


(Thermoplasma
acidophilum)
PF01884
(PcrB)
3 GLY A 175
GLY A 139
GLY A 135
None
0.30A 3bogC-5b69A:
undetectable
3bogC-5b69A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fsb TECTONIN 2

(Laccaria
bicolor)
no annotation 3 GLY A 169
GLY A  91
GLY A 129
None
0.40A 3bogC-5fsbA:
undetectable
3bogC-5fsbA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ghf AMINOTRANSFERASE
CLASS-III


(Ochrobactrum
anthropi)
PF00202
(Aminotran_3)
3 GLY A 268
GLY A 355
GLY A 378
None
0.39A 3bogC-5ghfA:
undetectable
3bogC-5ghfA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gly GLYCOSIDE HYDROLASE
FAMILY 45 PROTEIN


(Thielavia
terrestris)
PF02015
(Glyco_hydro_45)
3 GLY A 129
GLY A 145
GLY A 150
CTR  A 302 (-3.5A)
None
None
0.31A 3bogC-5glyA:
undetectable
3bogC-5glyA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gxf ACRYLYL-COA
REDUCTASE ACUI


(Ruegeria
pomeroyi)
PF00107
(ADH_zinc_N)
3 GLY A 100
GLY A  94
GLY A  65
None
0.42A 3bogC-5gxfA:
undetectable
3bogC-5gxfA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gz4 SNAKE VENOM
PHOSPHODIESTERASE
(PDE)


(Naja atra)
PF01033
(Somatomedin_B)
PF01223
(Endonuclease_NS)
PF01663
(Phosphodiest)
3 GLY A 459
GLY A 308
GLY A 312
None
0.29A 3bogC-5gz4A:
undetectable
3bogC-5gz4A:
6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h4u ENDO-BETA-1,4-GLUCAN
ASE


(Cryptopygus
antarcticus)
PF02015
(Glyco_hydro_45)
3 GLY A 129
GLY A 148
GLY A 153
None
0.39A 3bogC-5h4uA:
undetectable
3bogC-5h4uA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hxk ZINC-DEPENDENT
PEPTIDASE


(Thermus
thermophilus)
PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
3 GLY A 242
GLY A 286
GLY A 291
GLY  A 242 ( 0.0A)
GLY  A 286 ( 0.0A)
GLY  A 291 ( 0.0A)
0.42A 3bogC-5hxkA:
undetectable
3bogC-5hxkA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ik8 LAMININ SUBUNIT
ALPHA-2


(Mus musculus)
PF00054
(Laminin_G_1)
PF02210
(Laminin_G_2)
3 GLY A2975
GLY A3073
GLY A2985
None
0.42A 3bogC-5ik8A:
undetectable
3bogC-5ik8A:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2


(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae)
PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
3 GLY B1142
GLY A1061
GLY A1437
None
0.40A 3bogC-5ip9B:
undetectable
3bogC-5ip9B:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k1s OXIDOREDUCTASE,
ZINC-BINDING
DEHYDROGENASE FAMILY


(Myxococcus
xanthus)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
3 GLY A 120
GLY A 114
GLY A  61
None
0.41A 3bogC-5k1sA:
undetectable
3bogC-5k1sA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lnk MITOCHONDRIAL
COMPLEX I, 39 KDA
SUBUNIT


(Ovis aries)
no annotation 3 GLY d  12
GLY d  39
GLY d  42
None
0.26A 3bogC-5lnkd:
undetectable
3bogC-5lnkd:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME


(Lysobacter sp.
XL1)
no annotation 3 GLY A 146
GLY A   5
GLY A  20
None
0.43A 3bogC-5mrrA:
undetectable
3bogC-5mrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mrt LYTIC ENDOPEPTIDASE
PREPROENZYME


(Lysobacter sp.
XL1)
no annotation 3 GLY A 151
GLY A   5
GLY A  24
None
0.41A 3bogC-5mrtA:
undetectable
3bogC-5mrtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mrw POTASSIUM-TRANSPORTI
NG ATPASE
POTASSIUM-BINDING
SUBUNIT


(Escherichia
coli)
PF03814
(KdpA)
3 GLY A 468
GLY A 232
GLY A 345
K  A 601 ( 4.9A)
None
K  A 601 ( 4.8A)
0.40A 3bogC-5mrwA:
undetectable
3bogC-5mrwA:
9.34