SIMILAR PATTERNS OF AMINO ACIDS FOR 3BJW_H_SVRH511_3

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1as4 ANTICHYMOTRYPSIN

(Homo sapiens) 		PF00079
(Serpin) 		4 VAL A 183
ILE A 321
GLY A 320
ARG A 325
 None
 0.83A 3bjwH-1as4A:
undetectable		 3bjwH-1as4A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bgc GRANULOCYTE
COLONY-STIMULATING
FACTOR

(Bos taurus) 		PF16647
(GCSF) 		4 GLN A 146
GLY A 150
ARG A 148
LEU A  36
 None
 0.91A 3bjwH-1bgcA:
undetectable		 3bjwH-1bgcA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bru ELASTASE

(Sus scrofa) 		PF00089
(Trypsin) 		4 VAL P  90
ILE P 212
GLY P 211
ARG P 230
 None
 0.78A 3bjwH-1bruP:
undetectable		 3bjwH-1bruP:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itk CATALASE-PEROXIDASE

(Haloarcula
marismortui) 		PF00141
(peroxidase) 		4 VAL A 716
ILE A 624
GLY A 625
ARG A 585
 None
 0.83A 3bjwH-1itkA:
0.0		 3bjwH-1itkA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kkr 3-METHYLASPARTATE
AMMONIA-LYASE

(Citrobacter
amalonaticus) 		PF05034
(MAAL_N)
PF07476
(MAAL_C) 		4 VAL A 317
ILE A 330
GLY A 358
ARG A 382
 None
 0.78A 3bjwH-1kkrA:
undetectable		 3bjwH-1kkrA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lwu FIBRINOGEN BETA
CHAIN

(Petromyzon
marinus) 		PF00147
(Fibrinogen_C)
PF08702
(Fib_alpha) 		4 VAL B 319
ILE B 248
GLY B 229
ARG B 237
 None
 0.79A 3bjwH-1lwuB:
undetectable		 3bjwH-1lwuB:
14.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mc2 ACUTOHAEMONLYSIN

(Deinagkistrodon
acutus) 		PF00068
(Phospholip_A2_1) 		4 GLN A1011
GLY A1014
ARG A1107
LEU A1110
 None
 0.23A 3bjwH-1mc2A:
21.1		 3bjwH-1mc2A:
56.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pyt CHYMOTRYPSINOGEN C

(Bos taurus) 		PF00089
(Trypsin) 		4 VAL D 790
ILE D 912
GLY D 911
ARG D 930
 None
 0.67A 3bjwH-1pytD:
undetectable		 3bjwH-1pytD:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)

(Homo sapiens) 		PF00753
(Lactamase_B)
PF16123
(HAGH_C) 		4 VAL A 130
ILE A 115
GLY A  78
LEU A  85
 None
 0.82A 3bjwH-1qh5A:
undetectable		 3bjwH-1qh5A:
17.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1s8h PHOSPHOLIPASE A2
HOMOLOG

(Agkistrodon
contortrix) 		PF00068
(Phospholip_A2_1) 		4 GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.41A 3bjwH-1s8hA:
20.4		 3bjwH-1s8hA:
62.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w99 PESTICIDIAL CRYSTAL
PROTEIN CRY4BA

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 VAL A 214
LYS A 218
ILE A 221
LEU A 175
 None
 0.57A 3bjwH-1w99A:
undetectable		 3bjwH-1w99A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xwm PHOSPHATE UPTAKE
REGULATOR

(Geobacillus
stearothermophilus) 		PF01895
(PhoU) 		4 VAL A  98
LYS A 102
ILE A 105
GLY A 108
 None
 0.75A 3bjwH-1xwmA:
1.5		 3bjwH-1xwmA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 ILE A1037
GLN A  10
GLY A1038
LEU A1000
 None
 0.57A 3bjwH-2b5mA:
undetectable		 3bjwH-2b5mA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bdv PHAGE-RELATED
CONSERVED
HYPOTHETICAL
PROTEIN, BB2244

(Bordetella
bronchiseptica) 		PF02586
(SRAP) 		4 VAL A  49
ILE A  95
GLY A 131
LEU A 191
 None
 0.59A 3bjwH-2bdvA:
undetectable		 3bjwH-2bdvA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1h DELTA-AMINOLEVULINIC
ACID DEHYDRATASE

(Prosthecochloris
vibrioformis) 		PF00490
(ALAD) 		4 VAL A  67
LYS A  71
GLY A  77
ARG A 328
 None
 0.90A 3bjwH-2c1hA:
undetectable		 3bjwH-2c1hA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fff PENICILLIN-BINDING
PROTEIN 1B

(Streptococcus
pneumoniae) 		PF00905
(Transpeptidase) 		4 ILE B 470
GLN B 474
GLY B 469
LEU B 509
 None
 0.72A 3bjwH-2fffB:
undetectable		 3bjwH-2fffB:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fvl ALDO-KETO REDUCTASE
FAMILY 1, MEMBER C4

(Homo sapiens) 		PF00248
(Aldo_ket_red) 		4 VAL A  35
LYS A  39
ILE A  42
GLY A  45
 None
 0.85A 3bjwH-2fvlA:
undetectable		 3bjwH-2fvlA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ipc PREPROTEIN
TRANSLOCASE SECA
SUBUNIT

(Thermus
thermophilus) 		PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD) 		4 VAL A 432
ILE A 544
GLY A 543
ARG A 541
 None
 0.78A 3bjwH-2ipcA:
undetectable		 3bjwH-2ipcA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j5b TYROSYL-TRNA
SYNTHETASE

(Acanthamoeba
polyphaga
mimivirus) 		PF00579
(tRNA-synt_1b) 		4 ILE A  30
GLN A  64
GLY A  62
LEU A   8
 ILE  A  30 ( 0.7A)
GLN  A  64 ( 0.6A)
GLY  A  62 ( 0.0A)
LEU  A   8 ( 0.6A)
 0.92A 3bjwH-2j5bA:
undetectable		 3bjwH-2j5bA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p7s AMPHINASE-2

(Rana pipiens) 		PF00074
(RnaseA) 		4 VAL A  66
LYS A  68
GLY A 112
LEU A  76
 None
 0.86A 3bjwH-2p7sA:
undetectable		 3bjwH-2p7sA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I

(Escherichia
coli) 		PF00365
(PFK) 		4 VAL A 202
LYS A 206
ILE A 209
GLY A 212
 None
 0.77A 3bjwH-2pfkA:
undetectable		 3bjwH-2pfkA:
15.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ph4 ZHAOERMIATOXIN

(Protobothrops
mangshanensis) 		PF00068
(Phospholip_A2_1) 		4 GLN A  11
GLY A  15
ARG A 107
LEU A 110
 None
 0.50A 3bjwH-2ph4A:
19.3		 3bjwH-2ph4A:
57.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q1d 2-KETO-3-DEOXY-D-ARA
BINONATE DEHYDRATASE

(Sulfolobus
solfataricus) 		PF01557
(FAA_hydrolase) 		4 VAL X 148
ILE X 279
GLY X 280
LEU X  57
 None
 0.86A 3bjwH-2q1dX:
undetectable		 3bjwH-2q1dX:
16.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		6 VAL A   3
ILE A  10
GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.59A 3bjwH-2qheA:
23.8		 3bjwH-2qheA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vgi PYRUVATE KINASE
ISOZYMES R/L

(Homo sapiens) 		PF00224
(PK)
PF02887
(PK_C) 		4 VAL A 101
LYS A 105
ILE A 108
GLY A 111
 None
 0.90A 3bjwH-2vgiA:
undetectable		 3bjwH-2vgiA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y7c TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN

(Escherichia
coli) 		PF02384
(N6_Mtase)
PF12161
(HsdM_N) 		4 VAL B  89
ILE B 244
GLY B 214
LEU B 257
 None
 0.85A 3bjwH-2y7cB:
undetectable		 3bjwH-2y7cB:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1

(Homo sapiens) 		PF02732
(ERCC4) 		4 VAL B 501
ILE B 545
GLY B 546
ARG B 551
 None
 0.80A 3bjwH-2ziuB:
undetectable		 3bjwH-2ziuB:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a4t PUTATIVE
METHYLTRANSFERASE
MJ0026

(Methanocaldococcus
jannaschii) 		PF01189
(Methyltr_RsmB-F) 		4 VAL A  35
ILE A  54
GLY A  55
LEU A  61
 None
 0.90A 3bjwH-3a4tA:
undetectable		 3bjwH-3a4tA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aib GLUCOSYLTRANSFERASE-
SI

(Streptococcus
mutans) 		PF02324
(Glyco_hydro_70) 		4 VAL A 752
ILE A 707
GLY A 738
LEU A 642
 None
 0.87A 3bjwH-3aibA:
undetectable		 3bjwH-3aibA:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dh9 THIOREDOXIN
REDUCTASE 1

(Drosophila
melanogaster) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 VAL A 155
ILE A 327
GLY A 289
ARG A 161
 None
 0.90A 3bjwH-3dh9A:
undetectable		 3bjwH-3dh9A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e9y ACETOLACTATE
SYNTHASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 VAL A 545
ILE A 521
GLY A 522
ARG A 156
 None
 0.92A 3bjwH-3e9yA:
undetectable		 3bjwH-3e9yA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3exh PYRUVATE
DEHYDROGENASE E1
COMPONENT SUBUNIT
BETA, MITOCHONDRIAL

(Homo sapiens) 		PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 VAL B 168
ILE B 157
GLY B  12
ARG B  19
 None
 0.92A 3bjwH-3exhB:
undetectable		 3bjwH-3exhB:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fb4 ADENYLATE KINASE

(Jeotgalibacillus
marinus) 		PF00406
(ADK)
PF05191
(ADK_lid) 		4 VAL A  90
ILE A  65
GLY A  66
LEU A  45
 None
 0.80A 3bjwH-3fb4A:
undetectable		 3bjwH-3fb4A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6r DIHYDROOROTATE
DEHYDROGENASE
HOMOLOG,
MITOCHONDRIAL

(Plasmodium
falciparum) 		PF01180
(DHO_dh) 		4 VAL A 322
LYS A 326
ILE A 329
GLY A 333
 None
 0.82A 3bjwH-3i6rA:
undetectable		 3bjwH-3i6rA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k70 EXODEOXYRIBONUCLEASE
V ALPHA CHAIN

(Escherichia
coli) 		PF13538
(UvrD_C_2)
PF13604
(AAA_30) 		4 VAL D 268
ILE D 199
ARG D 232
LEU D 225
 None
 0.85A 3bjwH-3k70D:
undetectable		 3bjwH-3k70D:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kgw ALANINE-GLYOXYLATE
AMINOTRANSFERASE

(Mus musculus) 		PF00266
(Aminotran_5) 		4 LYS A  83
ILE A  86
GLN A  87
LEU A 306
 None
 0.88A 3bjwH-3kgwA:
undetectable		 3bjwH-3kgwA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kkj AMINE OXIDASE,
FLAVIN-CONTAINING

(Pseudomonas
syringae group
genomosp. 3) 		PF01593
(Amino_oxidase)
PF13450
(NAD_binding_8) 		4 VAL A  69
ILE A  12
ARG A 117
LEU A  30
 None
 0.87A 3bjwH-3kkjA:
undetectable		 3bjwH-3kkjA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kkj AMINE OXIDASE,
FLAVIN-CONTAINING

(Pseudomonas
syringae group
genomosp. 3) 		PF01593
(Amino_oxidase)
PF13450
(NAD_binding_8) 		4 VAL A  69
ILE A  12
GLY A  11
ARG A 117
 None
None
FAD  A 401 (-2.9A)
None
 0.93A 3bjwH-3kkjA:
undetectable		 3bjwH-3kkjA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l7z PROBABLE EXOSOME
COMPLEX RNA-BINDING
PROTEIN 1

(Sulfolobus
solfataricus) 		no annotation 4 VAL C 188
ILE C 127
GLY C 149
LEU C 120
 None
 0.88A 3bjwH-3l7zC:
undetectable		 3bjwH-3l7zC:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1c ENVELOPE
GLYCOPROTEIN L

(Human
alphaherpesvirus
2) 		PF05259
(Herpes_UL1)
PF12524
(GlyL_C) 		4 VAL B  61
ILE B  67
GLY B  69
ARG B  86
 None
 0.90A 3bjwH-3m1cB:
undetectable		 3bjwH-3m1cB:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qkw NUCLEOTIDE SUGAR
SYNTHETASE-LIKE
PROTEIN

(Streptococcus
parasanguinis) 		no annotation 4 VAL A  27
ILE A  69
GLN A  71
LEU A  62
 None
 0.67A 3bjwH-3qkwA:
undetectable		 3bjwH-3qkwA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s4w FANCONI ANEMIA GROUP
D2 PROTEIN HOMOLOG

(Mus musculus) 		PF14631
(FancD2) 		4 VAL B 565
GLN B 560
GLY B 575
LEU B 611
 None
 0.85A 3bjwH-3s4wB:
undetectable		 3bjwH-3s4wB:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ssm METHYLTRANSFERASE

(Micromonospora
griseorubida) 		no annotation 4 VAL A  16
GLN A 229
GLY A 267
ARG A 265
 None
 0.79A 3bjwH-3ssmA:
undetectable		 3bjwH-3ssmA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3suc PRENECK APPENDAGE
PROTEIN

(Bacillus virus
phi29) 		PF11962
(Peptidase_G2)
PF12708
(Pectate_lyase_3) 		4 VAL A 382
ILE A 332
GLY A 331
ARG A 358
 None
 0.90A 3bjwH-3sucA:
undetectable		 3bjwH-3sucA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
UBIQUITIN-LIKE
PROTEIN
SMT3,RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Saccharomyces
cerevisiae;
Schizosaccharomyces
pombe) 		PF11976
(Rad60-SLD)
no annotation 		4 VAL A  66
ILE A   6
GLY A   7
LEU B 655
 None
CL  A1003 (-4.1A)
None
None
 0.69A 3bjwH-3tixA:
undetectable		 3bjwH-3tixA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN

(Streptococcus
pyogenes) 		PF09704
(Cas_Cas5d) 		4 VAL A  94
ILE A  43
GLY A  42
ARG A  37
 None
 0.80A 3bjwH-3vzhA:
undetectable		 3bjwH-3vzhA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE

(Archaeoglobus
fulgidus) 		PF02516
(STT3) 		4 VAL A 624
ILE A 574
GLY A 573
LEU A 603
 None
 0.69A 3bjwH-3wajA:
2.4		 3bjwH-3wajA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wwy D-LACTATE
DEHYDROGENASE

(Fusobacterium
nucleatum) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 VAL A 112
ILE A 231
GLY A 256
LEU A 250
 None
None
GOL  A 405 ( 3.8A)
None
 0.78A 3bjwH-3wwyA:
undetectable		 3bjwH-3wwyA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyy IRON-SULFUR CLUSTER
BINDING PROTEIN

(Carboxydothermus
hydrogenoformans) 		PF00111
(Fer2)
PF14574
(DUF4445) 		4 VAL X 487
ILE X 461
GLY X 460
ARG X 458
 None
 0.86A 3bjwH-3zyyX:
undetectable		 3bjwH-3zyyX:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aej COLLAGEN
ALPHA-1(III) CHAIN

(Homo sapiens) 		PF01410
(COLFI) 		4 VAL A 207
ILE A 220
GLY A 173
ARG A 217
 GOL  A1248 ( 4.4A)
None
None
None
 0.92A 3bjwH-4aejA:
undetectable		 3bjwH-4aejA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4av6 K(+)-STIMULATED
PYROPHOSPHATE-ENERGI
ZED SODIUM PUMP

(Thermotoga
maritima) 		PF03030
(H_PPase) 		4 VAL A 698
ILE A 503
GLY A 504
LEU A 448
 None
 0.72A 3bjwH-4av6A:
1.0		 3bjwH-4av6A:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cr6 N-ACYLMANNOSAMINE
1-DEHYDROGENASE

(Flavobacterium
sp. 141-8) 		PF13561
(adh_short_C2) 		4 VAL A 154
ILE A 151
GLY A  94
LEU A  68
 None
 0.82A 3bjwH-4cr6A:
undetectable		 3bjwH-4cr6A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h4f CHYMOTRYPSIN-C

(Homo sapiens) 		PF00089
(Trypsin) 		4 VAL A  90
ILE A 212
GLY A 211
ARG A 230
 None
 0.80A 3bjwH-4h4fA:
undetectable		 3bjwH-4h4fA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hou INTERFERON-INDUCED
PROTEIN WITH
TETRATRICOPEPTIDE
REPEATS 1

(Homo sapiens) 		PF13181
(TPR_8)
PF13424
(TPR_12) 		4 VAL A 221
ILE A 183
GLY A 180
LEU A 168
 None
 0.90A 3bjwH-4houA:
undetectable		 3bjwH-4houA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i0p HLA CLASS II
HISTOCOMPATIBILITY
ANTIGEN, DO ALPHA
CHAIN
HLA CLASS II
HISTOCOMPATIBILITY
ANTIGEN, DO BETA
CHAIN

(Homo sapiens) 		PF00969
(MHC_II_beta)
PF00993
(MHC_II_alpha)
PF07654
(C1-set) 		4 VAL C  91
ILE D 148
GLN D 156
GLY D 146
 None
 0.91A 3bjwH-4i0pC:
undetectable		 3bjwH-4i0pC:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iss ALLOPHANATE
HYDROLASE

(Kluyveromyces
lactis) 		PF01425
(Amidase) 		5 VAL A 538
LYS A 520
ILE A 546
GLY A 605
LEU A 493
 None
 1.47A 3bjwH-4issA:
undetectable		 3bjwH-4issA:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4it4 CG17282

(Drosophila
melanogaster) 		no annotation 4 VAL A 158
LYS A 162
ILE A 165
LEU A 173
 None
 0.59A 3bjwH-4it4A:
undetectable		 3bjwH-4it4A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jnh GAG POLYPROTEIN

(Simian foamy
virus) 		PF03276
(Gag_spuma) 		4 VAL A  18
ILE A  36
GLY A  37
ARG A  39
 None
 0.87A 3bjwH-4jnhA:
undetectable		 3bjwH-4jnhA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m9x CELL DEATH PROTEIN 4

(Caenorhabditis
elegans) 		PF00619
(CARD)
PF00931
(NB-ARC) 		4 VAL A 248
ILE A 180
GLY A 181
ARG A 102
 None
 0.72A 3bjwH-4m9xA:
undetectable		 3bjwH-4m9xA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Methanocaldococcus
jannaschii) 		PF02350
(Epimerase_2) 		4 VAL A  90
ILE A  19
GLY A 354
ARG A 356
 None
 0.91A 3bjwH-4nesA:
undetectable		 3bjwH-4nesA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4omj SEC14-LIKE PROTEIN 2

(Homo sapiens) 		PF00650
(CRAL_TRIO) 		4 VAL A 239
ILE A 258
GLY A  87
LEU A 131
 None
 0.81A 3bjwH-4omjA:
undetectable		 3bjwH-4omjA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p6v NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT A

(Vibrio cholerae) 		PF05896
(NQRA)
PF11973
(NQRA_SLBB) 		4 VAL A 165
ILE A 245
GLN A 242
LEU A 181
 None
 0.86A 3bjwH-4p6vA:
undetectable		 3bjwH-4p6vA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2c CRISPR-ASSOCIATED
HELICASE CAS3

(Thermobaculum
terrenum) 		PF00271
(Helicase_C) 		4 VAL A 845
ILE A 939
GLY A 938
LEU A 627
 None
 0.84A 3bjwH-4q2cA:
2.2		 3bjwH-4q2cA:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rnw NADPH DEHYDROGENASE
1

(Saccharomyces
pastorianus) 		PF00724
(Oxidored_FMN) 		4 VAL A 273
LYS A 277
ILE A 280
GLY A 283
 None
 0.89A 3bjwH-4rnwA:
undetectable		 3bjwH-4rnwA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rnx NADPH DEHYDROGENASE
1

(Saccharomyces
pastorianus) 		PF00724
(Oxidored_FMN) 		4 VAL A  23
LYS A  27
ILE A  30
GLY A  33
 None
 0.83A 3bjwH-4rnxA:
undetectable		 3bjwH-4rnxA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tmc OLD YELLOW ENZYME

(Kluyveromyces
marxianus) 		PF00724
(Oxidored_FMN) 		4 VAL A 174
LYS A 178
ILE A 181
GLY A 184
 None
 0.85A 3bjwH-4tmcA:
undetectable		 3bjwH-4tmcA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u9o NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT A

(Vibrio cholerae) 		PF05896
(NQRA)
PF11973
(NQRA_SLBB) 		4 VAL A 165
ILE A 245
GLN A 242
LEU A 181
 None
 0.88A 3bjwH-4u9oA:
undetectable		 3bjwH-4u9oA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uuo CYTOSOLIC MALATE
DEHYDROGENASE

(Trichomonas
vaginalis) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		5 VAL A  85
ILE A 106
GLN A 110
GLY A 105
LEU A 330
 None
 0.90A 3bjwH-4uuoA:
undetectable		 3bjwH-4uuoA:
15.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1

(Bothrops
jararacussu) 		PF00068
(Phospholip_A2_1) 		4 GLN A  11
GLY A  14
ARG A  97
LEU A 100
 None
 0.37A 3bjwH-4wtbA:
21.3		 3bjwH-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1

(Bothrops
jararacussu) 		PF00068
(Phospholip_A2_1) 		4 LYS A   7
GLY A  14
ARG A  97
LEU A 100
 None
 0.71A 3bjwH-4wtbA:
21.3		 3bjwH-4wtbA:
56.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ybq SOLUTE CARRIER
FAMILY 2,
FACILITATED GLUCOSE
TRANSPORTER MEMBER 5

(Rattus
norvegicus) 		PF00083
(Sugar_tr) 		4 VAL A 144
ILE A 398
ARG A 340
LEU A 344
 None
 0.89A 3bjwH-4ybqA:
0.7		 3bjwH-4ybqA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yd8 PROTEIN PTHB1

(Homo sapiens) 		PF14727
(PHTB1_N) 		4 VAL A 318
ILE A 305
GLY A 306
LEU A 326
 None
 0.87A 3bjwH-4yd8A:
undetectable		 3bjwH-4yd8A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ync NADPH DEHYDROGENASE
1

(Saccharomyces
pastorianus) 		PF00724
(Oxidored_FMN) 		4 VAL A 174
LYS A 178
ILE A 181
GLY A 184
 None
 0.86A 3bjwH-4yncA:
undetectable		 3bjwH-4yncA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z0t OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY

(Brucella ovis) 		PF00106
(adh_short) 		4 VAL A  34
ILE A  78
GLY A  76
ARG A  73
 None
 0.88A 3bjwH-4z0tA:
undetectable		 3bjwH-4z0tA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA

(Escherichia
coli) 		PF02917
(Pertussis_S1) 		4 VAL A  10
ILE A 130
GLY A 127
ARG A  20
 NAD  A 202 (-4.1A)
None
None
None
 0.92A 3bjwH-4z9dA:
undetectable		 3bjwH-4z9dA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zqi D-ALANINE--D-ALANINE
LIGASE

(Yersinia pestis) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 VAL A 115
ILE A 111
GLN A 105
LEU A 248
 None
 0.94A 3bjwH-4zqiA:
undetectable		 3bjwH-4zqiA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ay9 4-O-BETA-D-MANNOSYL-
D-GLUCOSE
PHOSPHORYLASE

(Ruminococcus
albus) 		PF04041
(Glyco_hydro_130) 		4 VAL A 232
ILE A 164
GLY A 142
ARG A 131
 None
 0.70A 3bjwH-5ay9A:
undetectable		 3bjwH-5ay9A:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b47 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT

(Sulfurisphaera
tokodaii) 		PF02775
(TPP_enzyme_C)
PF12367
(PFO_beta_C) 		4 VAL B  84
ILE B  33
GLY B  32
ARG B  29
 None
 0.75A 3bjwH-5b47B:
undetectable		 3bjwH-5b47B:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cju ISOBUTYRYL-COA
MUTASE FUSED

(Cupriavidus
metallidurans) 		PF01642
(MM_CoA_mutase)
PF02310
(B12-binding)
PF03308
(ArgK) 		4 VAL A  91
LYS A  95
ILE A  98
LEU A  74
 None
 0.75A 3bjwH-5cjuA:
undetectable		 3bjwH-5cjuA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d1l E3 UBIQUITIN-PROTEIN
LIGASE RNF25

(Homo sapiens) 		PF17123
(zf-RING_11) 		4 ILE B 251
GLN B 246
GLY B 250
ARG B 244
 None
 0.92A 3bjwH-5d1lB:
undetectable		 3bjwH-5d1lB:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5elx ATP-DEPENDENT RNA
HELICASE DBP5

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 VAL A 299
ILE A 304
GLN A 306
GLY A 434
 None
 0.73A 3bjwH-5elxA:
undetectable		 3bjwH-5elxA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fcl CRISPR-ASSOCIATED
ENDONUCLEASE CAS1

(Pectobacterium
atrosepticum) 		PF01867
(Cas_Cas1) 		4 VAL A 140
GLN A 175
GLY A 177
ARG A 173
 None
 0.89A 3bjwH-5fclA:
undetectable		 3bjwH-5fclA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fqd DNA DAMAGE-BINDING
PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 ILE A1037
GLN A  10
GLY A1038
LEU A1000
 None
 0.59A 3bjwH-5fqdA:
undetectable		 3bjwH-5fqdA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i8i UREA AMIDOLYASE

(Kluyveromyces
lactis) 		PF00289
(Biotin_carb_N)
PF01425
(Amidase)
PF02626
(CT_A_B)
PF02682
(CT_C_D)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		5 VAL A 538
LYS A 520
ILE A 546
GLY A 605
LEU A 493
 None
 1.46A 3bjwH-5i8iA:
undetectable		 3bjwH-5i8iA:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jw6 ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Aspergillus
fumigatus) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 VAL A 156
ILE A 344
GLY A 314
ARG A 309
 None
 0.83A 3bjwH-5jw6A:
undetectable		 3bjwH-5jw6A:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k3w CPUTA1

(Curtobacterium
pusillum) 		PF01063
(Aminotran_4) 		4 VAL A 199
ILE A 230
GLN A 228
LEU A  82
 None
 0.90A 3bjwH-5k3wA:
undetectable		 3bjwH-5k3wA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kl0 PHOSPHOGLUCOMUTASE

(Xanthomonas
citri) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 ILE A 393
GLY A 391
ARG A 302
LEU A 303
 None
None
G16  A 501 ( 3.6A)
None
 0.93A 3bjwH-5kl0A:
undetectable		 3bjwH-5kl0A:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lir SIGMA CROSS-REACTING
PROTEIN 27A
(SCRP-27A)

(Salmonella
enterica) 		PF01965
(DJ-1_PfpI) 		4 VAL A 217
ILE A   7
GLY A   8
LEU A 123
 None
 0.91A 3bjwH-5lirA:
undetectable		 3bjwH-5lirA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lm8 'MULTICOPPER OXIDASE

(Aspergillus
niger) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 140
ILE A  84
GLY A 166
ARG A 290
 None
 0.82A 3bjwH-5lm8A:
undetectable		 3bjwH-5lm8A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lrb ALPHA-1,4 GLUCAN
PHOSPHORYLASE

(Hordeum vulgare) 		PF00343
(Phosphorylase) 		4 VAL A 272
LYS A 270
ILE A 269
LEU A 440
 None
 0.91A 3bjwH-5lrbA:
undetectable		 3bjwH-5lrbA:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5npr UDP-N-ACETYLGLUCOSAM
INE--PEPTIDE
N-ACETYLGLUCOSAMINYL
TRANSFERASE 110 KDA
SUBUNIT

(Homo sapiens) 		no annotation 4 ILE A 876
GLN A 877
GLY A 872
ARG A 867
 None
 0.90A 3bjwH-5nprA:
undetectable		 3bjwH-5nprA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nth PUTATIVE
AMINOPEPTIDASE

(Leishmania
major) 		PF00883
(Peptidase_M17) 		4 VAL A 278
ILE A 264
GLY A 263
ARG A 257
 None
 0.82A 3bjwH-5nthA:
undetectable		 3bjwH-5nthA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tuc SUS TBC1D15 GAP
DOMAIN

(Sus scrofa) 		PF00566
(RabGAP-TBC) 		4 VAL A 318
LYS A 322
ILE A 325
GLY A 329
 None
 0.72A 3bjwH-5tucA:
undetectable		 3bjwH-5tucA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udb DNA REPLICATION
LICENSING FACTOR
MCM6

(Saccharomyces
cerevisiae) 		PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB) 		4 VAL 6 589
ILE 6 547
GLY 6 546
LEU 6 806
 None
 0.75A 3bjwH-5udb6:
undetectable		 3bjwH-5udb6:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w3w ARYLDIALKYLPHOSPHATA
SE

(Sulfolobus
solfataricus) 		no annotation 4 VAL A  50
LYS A  54
GLN A  58
GLY A  60
 None
 0.69A 3bjwH-5w3wA:
undetectable		 3bjwH-5w3wA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wcj METHYLTRANSFERASE-LI
KE PROTEIN 13

(Homo sapiens) 		PF01564
(Spermine_synth) 		4 VAL A 500
ILE A 612
GLY A 480
LEU A 672
 None
 0.89A 3bjwH-5wcjA:
undetectable		 3bjwH-5wcjA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2

(Homo sapiens) 		no annotation 4 VAL A   3
GLY A  14
ARG A  98
LEU A 101
 None
None
None
TRS  A 211 (-4.0A)
 0.52A 3bjwH-5wzmA:
20.3		 3bjwH-5wzmA:
29.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		no annotation 4 VAL A 496
ILE A 523
GLY A 524
ARG A 527
 None
 0.87A 3bjwH-5ze4A:
undetectable		 3bjwH-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ce2 -

(-) 		no annotation 4 VAL A   3
GLN A  11
GLY A  15
ARG A 107
 None
 0.66A 3bjwH-6ce2A:
20.5		 3bjwH-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fnu METHYLENETETRAHYDROF
OLATE REDUCTASE 1

(Saccharomyces
cerevisiae) 		no annotation 4 VAL A 262
ILE A 269
GLN A 270
LEU A 198
 None
 0.75A 3bjwH-6fnuA:
undetectable		 3bjwH-6fnuA:
13.93