SIMILAR PATTERNS OF AMINO ACIDS FOR 3BJW_H_SVRH511

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gmz PHOSPHOLIPASE A2

(Bothrops
pirajai) 		PF00068
(Phospholip_A2_1) 		5 LYS A  15
TYR A 103
ASN A 104
LYS A 105
TYR A 107
 None
 0.95A 3bjwC-1gmzA:
19.7		 3bjwC-1gmzA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1god PROTEIN
(PHOSPHOLIPASE A2)

(Cerrophidion
godmani) 		PF00068
(Phospholip_A2_1) 		5 LYS A  16
TYR A 113
ASN A 114
TYR A 117
PRO A 121
 None
 0.98A 3bjwC-1godA:
19.9		 3bjwC-1godA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA

(Daboia russelii) 		PF00068
(Phospholip_A2_1) 		5 LYS A  16
TYR A 113
TYR A 117
PRO A 121
PHE A 124
 None
 0.91A 3bjwC-1q6vA:
22.0		 3bjwC-1q6vA:
65.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		5 LYS A  16
TYR A 113
ASN A 114
TYR A 117
PRO A 121
 None
 1.33A 3bjwC-2qheA:
22.8		 3bjwC-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		5 LYS A  16
TYR A 113
LYS A 116
TYR A 117
PRO A 121
 None
 1.45A 3bjwC-2qheA:
22.8		 3bjwC-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1

(Bothrops
jararacussu) 		PF00068
(Phospholip_A2_1) 		5 LYS A  15
TYR A 103
ASN A 104
TYR A 107
PHE A 114
 None
None
None
SO4  A 203 (-4.4A)
None
 0.97A 3bjwC-4wtbA:
20.4		 3bjwC-4wtbA:
56.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e0t PYRUVATE KINASE

(Escherichia
coli) 		PF00224
(PK)
PF02887
(PK_C) 		4 VAL A   7
VAL A  30
THR A 306
THR A   9
 None
 1.22A 3bjwD-1e0tA:
0.0		 3bjwD-1e0tA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fux HYPOTHETICAL 19.5
KDA PROTEIN IN
EMRE-RUS INTERGENIC
REGION

(Escherichia
coli) 		PF01161
(PBP) 		4 VAL A  67
VAL A  93
THR A 127
THR A  65
 None
 0.98A 3bjwD-1fuxA:
0.0		 3bjwD-1fuxA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i2l 4-AMINO-4-DEOXYCHORI
SMATE LYASE

(Escherichia
coli) 		PF01063
(Aminotran_4) 		4 VAL A 187
VAL A 186
THR A 256
THR A 189
 None
 1.28A 3bjwD-1i2lA:
0.0		 3bjwD-1i2lA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iq0 ARGINYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1) 		4 VAL A 104
VAL A 105
THR A 343
ARG A 141
 None
 1.24A 3bjwD-1iq0A:
0.0		 3bjwD-1iq0A:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k8g TELOMERE-BINDING
PROTEIN ALPHA
SUBUNIT

(Sterkiella nova) 		PF02765
(POT1) 		4 VAL A 226
VAL A 227
THR A 255
THR A 212
 None
 1.28A 3bjwD-1k8gA:
0.0		 3bjwD-1k8gA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mg5 ALCOHOL
DEHYDROGENASE

(Drosophila
melanogaster) 		PF00106
(adh_short) 		4 VAL A 159
VAL A 160
THR A 116
THR A 155
 None
 1.28A 3bjwD-1mg5A:
0.0		 3bjwD-1mg5A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n8p CYSTATHIONINE
GAMMA-LYASE

(Saccharomyces
cerevisiae) 		PF01053
(Cys_Met_Meta_PP) 		4 VAL A 198
VAL A 197
THR A  85
THR A 180
 None
None
None
PLP  A 400 ( 4.1A)
 1.04A 3bjwD-1n8pA:
0.0		 3bjwD-1n8pA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nyo IMMUNOGENIC PROTEIN
MPT70

(Mycobacterium
tuberculosis) 		PF02469
(Fasciclin) 		4 VAL A 102
VAL A 103
THR A 147
THR A  99
 None
 1.30A 3bjwD-1nyoA:
undetectable		 3bjwD-1nyoA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ph5 TELOMERE-BINDING
PROTEIN ALPHA
SUBUNIT

(Sterkiella nova) 		PF02765
(POT1) 		4 VAL A 226
VAL A 227
THR A 255
THR A 212
 None
 1.27A 3bjwD-1ph5A:
0.0		 3bjwD-1ph5A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r26 THIOREDOXIN

(Trypanosoma
brucei) 		PF00085
(Thioredoxin) 		4 VAL A   2
VAL A   3
THR A  26
ARG A  -2
 None
 1.25A 3bjwD-1r26A:
undetectable		 3bjwD-1r26A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v84 GALACTOSYLGALACTOSYL
XYLOSYLPROTEIN
3-BETA-GLUCURONOSYLT
RANSFERASE 1

(Homo sapiens) 		PF03360
(Glyco_transf_43) 		4 VAL A 112
THR A 137
THR A  85
ARG A 209
 None
 1.12A 3bjwD-1v84A:
undetectable		 3bjwD-1v84A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x0l HOMOISOCITRATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00180
(Iso_dh) 		4 VAL A  24
VAL A 328
THR A 275
THR A  28
 None
 1.28A 3bjwD-1x0lA:
undetectable		 3bjwD-1x0lA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2acg PROFILIN II

(Acanthamoeba
castellanii) 		PF00235
(Profilin) 		4 VAL A 112
VAL A 113
THR A   8
THR A 108
 None
 1.26A 3bjwD-2acgA:
undetectable		 3bjwD-2acgA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ddw PYRIDOXINE KINASE

(Escherichia
coli) 		PF08543
(Phos_pyr_kin) 		4 VAL A 192
VAL A 193
THR A 167
THR A 212
 None
 1.29A 3bjwD-2ddwA:
undetectable		 3bjwD-2ddwA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gah HETEROTETRAMERIC
SARCOSINE OXIDASE
ALPHA-SUBUNIT

(Stenotrophomonas
maltophilia) 		PF01571
(GCV_T)
PF07992
(Pyr_redox_2)
PF08669
(GCV_T_C)
PF13510
(Fer2_4) 		4 VAL A 339
VAL A 355
THR A 291
THR A 342
 None
 1.26A 3bjwD-2gahA:
undetectable		 3bjwD-2gahA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gqw FERREDOXIN REDUCTASE

(Pseudomonas sp.
KKS102) 		PF07992
(Pyr_redox_2)
PF14759
(Reductase_C) 		4 VAL A 106
VAL A  12
THR A 275
THR A 104
 None
 1.05A 3bjwD-2gqwA:
undetectable		 3bjwD-2gqwA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j4r EXOPOLYPHOSPHATASE

(Aquifex
aeolicus) 		PF02541
(Ppx-GppA) 		4 VAL A 207
VAL A 139
THR A 214
THR A 205
 None
 1.29A 3bjwD-2j4rA:
undetectable		 3bjwD-2j4rA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jd4 LAMININ SUBUNIT
ALPHA-1

(Mus musculus) 		PF00054
(Laminin_G_1)
PF02210
(Laminin_G_2) 		4 VAL A2785
VAL A2798
THR A2730
THR A2787
 None
 1.23A 3bjwD-2jd4A:
undetectable		 3bjwD-2jd4A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE

(Mycobacterium
tuberculosis) 		PF13399
(LytR_C) 		4 VAL A  39
VAL A  66
THR A  77
THR A  64
 None
 1.24A 3bjwD-2m5yA:
undetectable		 3bjwD-2m5yA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nq5 5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE

(Streptococcus
mutans) 		PF01717
(Meth_synt_2)
PF08267
(Meth_synt_1) 		4 VAL A 693
VAL A 694
THR A 417
THR A 689
 None
 1.19A 3bjwD-2nq5A:
undetectable		 3bjwD-2nq5A:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pi5 DNA-DIRECTED RNA
POLYMERASE

(Escherichia
virus T7) 		PF00940
(RNA_pol)
PF14700
(RPOL_N) 		4 VAL A 137
VAL A 134
THR A 118
THR A 132
 None
 1.01A 3bjwD-2pi5A:
undetectable		 3bjwD-2pi5A:
9.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		4 VAL A   2
THR A  23
THR A  70
ARG A  72
 None
 1.27A 3bjwD-2qheA:
22.8		 3bjwD-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		4 VAL A   2
VAL A   3
THR A  23
THR A  70
 None
 0.69A 3bjwD-2qheA:
22.8		 3bjwD-2qheA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qlu ACTIVIN RECEPTOR
TYPE IIB

(Homo sapiens) 		PF00069
(Pkinase) 		4 VAL A 336
VAL A 327
THR A 265
THR A 334
 None
None
ADE  A 488 (-4.3A)
None
 1.24A 3bjwD-2qluA:
undetectable		 3bjwD-2qluA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r94 2-KETO-3-DEOXY-(6-PH
OSPHO-)GLUCONATE
ALDOLASE

(Thermoproteus
tenax) 		PF00701
(DHDPS) 		4 VAL A  56
VAL A  55
THR A  77
THR A  49
 None
 1.28A 3bjwD-2r94A:
undetectable		 3bjwD-2r94A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wpm COAGULATION FACTOR
IXA HEAVY CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		4 VAL S  65
VAL S  32
THR S  79
THR S  64
 None
 1.06A 3bjwD-2wpmS:
undetectable		 3bjwD-2wpmS:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xrc HUMAN COMPLEMENT
FACTOR I

(Homo sapiens) 		PF00057
(Ldl_recept_a)
PF00089
(Trypsin)
PF00530
(SRCR) 		4 VAL A 522
VAL A 436
THR A 359
THR A 520
 None
 1.22A 3bjwD-2xrcA:
undetectable		 3bjwD-2xrcA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yq4 D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE

(Lactobacillus
delbrueckii) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 VAL A  62
VAL A  61
THR A  89
THR A  36
 None
 1.24A 3bjwD-2yq4A:
1.5		 3bjwD-2yq4A:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbc 83AA LONG
HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR ASNC

(Sulfurisphaera
tokodaii) 		PF01037
(AsnC_trans_reg) 		4 VAL A  42
VAL A  31
THR A  69
THR A  29
 None
None
ILE  A  84 (-3.6A)
None
 1.16A 3bjwD-2zbcA:
undetectable		 3bjwD-2zbcA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a1i AMIDASE

(Rhodococcus sp.
N-771) 		PF01425
(Amidase) 		4 VAL A 125
VAL A 124
THR A  83
THR A 100
 None
 1.26A 3bjwD-3a1iA:
undetectable		 3bjwD-3a1iA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b8y ENDO-PECTATE LYASE

(Dickeya
chrysanthemi) 		PF03211
(Pectate_lyase) 		4 VAL A 237
VAL A 268
THR A 242
THR A 235
 None
 1.27A 3bjwD-3b8yA:
undetectable		 3bjwD-3b8yA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b90 ENDO-PECTATE LYASE

(Dickeya
chrysanthemi) 		PF03211
(Pectate_lyase) 		4 VAL A 237
VAL A 268
THR A 242
THR A 235
 None
 1.24A 3bjwD-3b90A:
undetectable		 3bjwD-3b90A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bzb UNCHARACTERIZED
PROTEIN

(Cyanidioschyzon
merolae) 		PF10294
(Methyltransf_16) 		4 VAL A 105
VAL A 106
THR A 127
THR A  82
 None
 1.30A 3bjwD-3bzbA:
undetectable		 3bjwD-3bzbA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dto BH2835 PROTEIN

(Bacillus
halodurans) 		PF01966
(HD) 		4 VAL A 118
VAL A 117
THR A  99
THR A  34
 None
 0.86A 3bjwD-3dtoA:
undetectable		 3bjwD-3dtoA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e18 OXIDOREDUCTASE

(Listeria
innocua) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 VAL A 226
VAL A 151
THR A 212
THR A 228
 None
GOL  A 365 (-3.7A)
None
None
 1.22A 3bjwD-3e18A:
undetectable		 3bjwD-3e18A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f6z PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF09864
(MliC) 		4 VAL B  71
VAL B  81
THR B  44
THR B  79
 None
 1.04A 3bjwD-3f6zB:
undetectable		 3bjwD-3f6zB:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gec PERIOD CIRCADIAN
PROTEIN

(Drosophila
melanogaster) 		PF00989
(PAS)
PF14598
(PAS_11) 		4 VAL A 489
VAL A 490
THR A 439
THR A 396
 None
 1.08A 3bjwD-3gecA:
undetectable		 3bjwD-3gecA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3glg DNA POLYMERASE III
SUBUNIT DELTA'

(Escherichia
coli) 		PF09115
(DNApol3-delta_C)
PF13177
(DNA_pol3_delta2) 		4 VAL E 112
VAL E 111
THR E 131
THR E  78
 None
 1.19A 3bjwD-3glgE:
1.1		 3bjwD-3glgE:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h09 IMMUNOGLOBULIN A1
PROTEASE

(Haemophilus
influenzae) 		PF02395
(Peptidase_S6)
PF03212
(Pertactin) 		4 VAL A 737
VAL A 736
THR A 802
THR A 712
 None
 1.30A 3bjwD-3h09A:
undetectable		 3bjwD-3h09A:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrd NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT

(Eubacterium
barkeri) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 VAL A 204
VAL A 192
THR A 234
THR A 202
 None
 1.02A 3bjwD-3hrdA:
undetectable		 3bjwD-3hrdA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iha SALT-TOLERANT
GLUTAMINASE

(Micrococcus
luteus) 		PF04960
(Glutaminase) 		4 VAL A 234
VAL A 233
THR A 213
THR A 238
 None
 1.21A 3bjwD-3ihaA:
undetectable		 3bjwD-3ihaA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jsk CYPBP37 PROTEIN

(Neurospora
crassa) 		PF01946
(Thi4) 		4 VAL A 110
VAL A  85
THR A 221
THR A 108
 None
AHZ  A 500 (-4.8A)
None
None
 1.23A 3bjwD-3jskA:
0.7		 3bjwD-3jskA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kya PUTATIVE PHOSPHATASE

(Bacteroides
thetaiotaomicron) 		PF01833
(TIG) 		4 VAL A 434
VAL A 428
THR A 389
THR A 436
 None
 1.24A 3bjwD-3kyaA:
undetectable		 3bjwD-3kyaA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ldr FRUCTOSYLTRANSFERASE

(Aspergillus
japonicus) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 VAL A 594
VAL A 595
THR A 537
THR A 509
 None
 1.23A 3bjwD-3ldrA:
undetectable		 3bjwD-3ldrA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lml LIN1278 PROTEIN

(Listeria
innocua) 		PF04984
(Phage_sheath_1)
PF17481
(Phage_sheath_1N)
PF17482
(Phage_sheath_1C) 		4 VAL A 136
VAL A 124
THR A 152
THR A 138
 None
 1.27A 3bjwD-3lmlA:
undetectable		 3bjwD-3lmlA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m66 MTERF
DOMAIN-CONTAINING
PROTEIN 1,
MITOCHONDRIAL

(Homo sapiens) 		PF02536
(mTERF) 		4 VAL A 280
VAL A 281
THR A 288
THR A 276
 None
 0.84A 3bjwD-3m66A:
undetectable		 3bjwD-3m66A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mcz O-METHYLTRANSFERASE

(Burkholderia
thailandensis) 		PF00891
(Methyltransf_2)
PF16864
(Dimerisation2) 		4 VAL A 168
VAL A 167
THR A 189
ARG A 333
 None
 0.99A 3bjwD-3mczA:
undetectable		 3bjwD-3mczA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mfd D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACB

(Bacillus
subtilis) 		PF00768
(Peptidase_S11)
PF07943
(PBP5_C) 		4 VAL A 232
VAL A 245
THR A  62
THR A 234
 None
 1.23A 3bjwD-3mfdA:
undetectable		 3bjwD-3mfdA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qt2 INTERLEUKIN-5
RECEPTOR SUBUNIT
ALPHA

(Homo sapiens) 		PF09240
(IL6Ra-bind) 		4 VAL A  78
VAL A  47
THR A  17
THR A  80
 None
 1.28A 3bjwD-3qt2A:
undetectable		 3bjwD-3qt2A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rd5 MYPAA.01249.C

(Mycobacterium
avium) 		PF00106
(adh_short) 		4 VAL A  17
VAL A  18
THR A 233
THR A  40
 None
 1.23A 3bjwD-3rd5A:
undetectable		 3bjwD-3rd5A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3riq TAILSPIKE PROTEIN

(Salmonella
virus 9NA) 		PF09251
(PhageP22-tail) 		4 VAL A 378
VAL A 350
THR A 401
THR A 380
 None
 1.05A 3bjwD-3riqA:
undetectable		 3bjwD-3riqA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rq1 AMINOTRANSFERASE
CLASS I AND II

(Veillonella
parvula) 		PF00155
(Aminotran_1_2) 		4 VAL A 126
VAL A 179
THR A 143
THR A 128
 None
 1.06A 3bjwD-3rq1A:
undetectable		 3bjwD-3rq1A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rty PERIOD CIRCADIAN
PROTEIN

(Drosophila
melanogaster) 		PF00989
(PAS)
PF14598
(PAS_11) 		4 VAL A 489
VAL A 490
THR A 439
THR A 396
 None
 0.97A 3bjwD-3rtyA:
undetectable		 3bjwD-3rtyA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t05 PYRUVATE KINASE

(Staphylococcus
aureus) 		PF00224
(PK)
PF00391
(PEP-utilizers)
PF02887
(PK_C) 		4 VAL A   7
VAL A  30
THR A 305
THR A   9
 None
 1.24A 3bjwD-3t05A:
undetectable		 3bjwD-3t05A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ug7 ARSENICAL
PUMP-DRIVING ATPASE

(Methanocaldococcus
jannaschii) 		PF02374
(ArsA_ATPase) 		4 VAL A  91
VAL A  58
THR A  40
THR A  81
 None
None
MG  A 403 ( 3.2A)
None
 1.15A 3bjwD-3ug7A:
undetectable		 3bjwD-3ug7A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a1o BIFUNCTIONAL PURINE
BIOSYNTHESIS PROTEIN
PURH

(Mycobacterium
tuberculosis) 		PF01808
(AICARFT_IMPCHas)
PF02142
(MGS) 		4 VAL A 108
VAL A  17
THR A  73
THR A 152
 None
None
JLN  A1528 (-2.7A)
None
 1.27A 3bjwD-4a1oA:
undetectable		 3bjwD-4a1oA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bju N-ACETYLGLUCOSAMINE-
PHOSPHATE MUTASE

(Aspergillus
fumigatus) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I) 		4 VAL A 335
VAL A 357
THR A 388
THR A 337
 None
 1.03A 3bjwD-4bjuA:
undetectable		 3bjwD-4bjuA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cgy DNA TOPOISOMERASE
3-ALPHA

(Homo sapiens) 		PF01131
(Topoisom_bac)
PF01751
(Toprim) 		4 VAL A 252
VAL A 253
THR A 554
THR A 248
 None
 1.02A 3bjwD-4cgyA:
undetectable		 3bjwD-4cgyA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cp6 CHOLINE BINDING
PROTEIN PCPA

(Streptococcus
pneumoniae) 		PF13306
(LRR_5) 		4 VAL A  53
VAL A  40
THR A  99
THR A  38
 None
 1.04A 3bjwD-4cp6A:
undetectable		 3bjwD-4cp6A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0s 5-METHYLTHIOADENOSIN
E/S-ADENOSYLHOMOCYST
EINE DEAMINASE

(Chromobacterium
violaceum) 		PF01979
(Amidohydro_1) 		4 VAL A 205
VAL A 206
THR A 188
THR A 201
 None
 0.86A 3bjwD-4f0sA:
undetectable		 3bjwD-4f0sA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g9y PCAV TRANSCRIPTIONAL
REGULATOR

(Streptomyces
coelicolor) 		PF13463
(HTH_27) 		4 VAL A  69
VAL A  70
THR A  33
THR A  65
 None
 0.93A 3bjwD-4g9yA:
undetectable		 3bjwD-4g9yA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gbo E7

(Thermobifida
fusca) 		PF03067
(LPMO_10) 		4 VAL A 200
VAL A 153
THR A 127
THR A 202
 None
None
IOD  A 314 (-3.5A)
None
 1.23A 3bjwD-4gboA:
undetectable		 3bjwD-4gboA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hl4 TBC1 DOMAIN FAMILY
MEMBER 20

(Homo sapiens) 		PF00566
(RabGAP-TBC) 		4 VAL A 235
VAL A 236
THR A 223
ARG A 233
 None
 1.27A 3bjwD-4hl4A:
undetectable		 3bjwD-4hl4A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iyo CYSTATHIONINE
GAMMA-LYASE-LIKE
PROTEIN, LYS201A
MODIFIED

(Xanthomonas
oryzae) 		PF01053
(Cys_Met_Meta_PP) 		4 VAL B 205
VAL B 204
THR B  94
THR B 187
 None
None
None
LLP  B 210 ( 3.8A)
 1.15A 3bjwD-4iyoB:
undetectable		 3bjwD-4iyoB:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4js7 CELLULOSE BINDING
PROTEIN

(Clavibacter
michiganensis) 		PF01357
(Pollen_allerg_1)
PF03330
(DPBB_1) 		4 VAL A 179
VAL A 180
THR A 109
THR A 172
 None
 1.29A 3bjwD-4js7A:
undetectable		 3bjwD-4js7A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l7v PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Vibrio cholerae) 		PF01135
(PCMT) 		4 VAL A  79
VAL A 100
THR A 148
THR A  77
 None
None
SAH  A 301 (-3.4A)
None
 1.14A 3bjwD-4l7vA:
undetectable		 3bjwD-4l7vA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4li3 CYSTEINE SYNTHASE

(Haemophilus
influenzae) 		PF00291
(PALP) 		4 VAL X 172
VAL X 173
THR X 157
THR X 198
 None
 1.23A 3bjwD-4li3X:
undetectable		 3bjwD-4li3X:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lls GERANYLTRANSTRANSFER
ASE

(Roseobacter
denitrificans) 		PF00348
(polyprenyl_synt) 		4 VAL A 284
VAL A 285
THR A 179
THR A 280
 None
None
IPE  A 301 (-4.2A)
None
 1.22A 3bjwD-4llsA:
1.3		 3bjwD-4llsA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ls9 DHH FAMILY PROTEIN

(Mycolicibacterium
smegmatis) 		PF01368
(DHH)
PF02272
(DHHA1) 		4 VAL A 273
VAL A 270
THR A 235
THR A 275
 None
 1.28A 3bjwD-4ls9A:
undetectable		 3bjwD-4ls9A:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nky STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE

(Homo sapiens) 		PF00067
(p450) 		4 VAL A 310
VAL A 311
THR A 356
THR A 306
 None
None
None
HEM  A 600 ( 3.2A)
 1.19A 3bjwD-4nkyA:
undetectable		 3bjwD-4nkyA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oy8 PUTATIVE SECRETED
CELLULOSE-BINDING
PROTEIN

(Streptomyces
coelicolor) 		PF03067
(LPMO_10) 		4 VAL A 206
VAL A 159
THR A 133
THR A 208
 None
 1.24A 3bjwD-4oy8A:
undetectable		 3bjwD-4oy8A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pmz XYLANASE

(Xanthomonas
citri) 		PF00331
(Glyco_hydro_10) 		4 VAL A 233
THR A 199
THR A 228
ARG A 271
 None
 1.26A 3bjwD-4pmzA:
undetectable		 3bjwD-4pmzA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE

(Aspergillus
fumigatus) 		PF01233
(NMT)
PF02799
(NMT_C) 		4 VAL A 359
VAL A 358
THR A 300
THR A 368
 None
 1.25A 3bjwD-4qbjA:
undetectable		 3bjwD-4qbjA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qdk MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE

(Synechocystis
sp. PCC 6803) 		PF07109
(Mg-por_mtran_C) 		4 VAL A  51
VAL A  52
THR A 130
THR A  47
 None
 0.96A 3bjwD-4qdkA:
undetectable		 3bjwD-4qdkA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r27 GLYCOSIDE HYDROLASE

(Microbacterium
sp. Gsoil167) 		PF00232
(Glyco_hydro_1) 		4 VAL A 122
VAL A 166
THR A  81
THR A 124
 None
 1.04A 3bjwD-4r27A:
undetectable		 3bjwD-4r27A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rp8 ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA

(Escherichia
coli) 		PF03611
(EIIC-GAT) 		4 VAL A  69
VAL A  70
THR A 255
THR A  65
 None
 1.29A 3bjwD-4rp8A:
1.1		 3bjwD-4rp8A:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u1d EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT A

(Saccharomyces
cerevisiae) 		no annotation 4 VAL C 182
VAL C 183
THR C 158
THR C 178
 None
 1.25A 3bjwD-4u1dC:
undetectable		 3bjwD-4u1dC:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3a ENDOGLUCANASE H

(Ruminiclostridium
thermocellum) 		PF00150
(Cellulase) 		4 VAL A 239
THR A 163
THR A 236
ARG A 231
 None
 1.09A 3bjwD-4u3aA:
undetectable		 3bjwD-4u3aA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uer EIF3A

(Lachancea
kluyveri) 		no annotation 4 VAL a 182
VAL a 183
THR a 158
THR a 178
 None
 1.23A 3bjwD-4uera:
undetectable		 3bjwD-4uera:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zfz MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS I

(Macaca mulatta) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 VAL A  24
VAL A  25
THR A  64
THR A  10
 None
 1.24A 3bjwD-4zfzA:
undetectable		 3bjwD-4zfzA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a8r METHYL-COENZYME M
REDUCTASE II SUBUNIT
GAMMA

(Methanothermobacter
marburgensis) 		PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		4 VAL B 201
VAL B 200
THR B 411
THR B 208
 None
 1.19A 3bjwD-5a8rB:
0.9		 3bjwD-5a8rB:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aca VP1

(Foot-and-mouth
disease virus) 		PF00073
(Rhv) 		4 VAL 1  35
VAL 1  32
THR 1  40
THR 1  30
 None
 1.23A 3bjwD-5aca1:
undetectable		 3bjwD-5aca1:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bq3 RHAMNOSE ABC
TRANSPORTER,
RHAMNOSE-BINDING
PROTEIN

(Actinomyces
odontolyticus) 		PF13407
(Peripla_BP_4) 		4 VAL A 334
VAL A 335
THR A 135
THR A 327
 None
 1.25A 3bjwD-5bq3A:
undetectable		 3bjwD-5bq3A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cdi CHAPERONIN 60B1

(Chlamydomonas
reinhardtii) 		PF00118
(Cpn60_TCP1) 		4 VAL A 175
VAL A 176
THR A 325
THR A 173
 None
 1.27A 3bjwD-5cdiA:
undetectable		 3bjwD-5cdiA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dll AMINOPEPTIDASE N

(Francisella
tularensis) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		4 VAL A  41
VAL A 105
THR A  28
THR A  39
 NA  A 917 (-4.6A)
NA  A 917 ( 4.1A)
None
None
 0.89A 3bjwD-5dllA:
undetectable		 3bjwD-5dllA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dm6 50S RIBOSOMAL
PROTEIN L1

(Deinococcus
radiodurans) 		PF00687
(Ribosomal_L1) 		4 VAL 0 166
VAL 0 167
THR 0 211
THR 0 164
 C  X2178 ( 4.3A)
None
A  X2176 ( 3.8A)
C  X2179 ( 3.3A)
 1.25A 3bjwD-5dm60:
undetectable		 3bjwD-5dm60:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dmh UNCHARACTERIZED
PROTEIN CONSERVED IN
BACTERIA

(Cupriavidus
necator) 		PF07005
(DUF1537)
PF17042
(DUF1357_C) 		4 VAL A 377
VAL A 378
THR A 363
THR A 373
 None
None
None
ADP  A 501 (-3.8A)
 1.16A 3bjwD-5dmhA:
undetectable		 3bjwD-5dmhA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eog PROTEIN MAB-21-LIKE
1

(Homo sapiens) 		PF03281
(Mab-21) 		4 VAL A 167
VAL A 168
THR A 155
THR A  72
 None
 1.18A 3bjwD-5eogA:
undetectable		 3bjwD-5eogA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fzp DISPASE
AUTOLYSIS-INDUCING
PROTEIN

(Streptomyces
mobaraensis) 		no annotation 4 VAL A 193
VAL A 183
THR A 205
THR A 195
 None
 1.19A 3bjwD-5fzpA:
undetectable		 3bjwD-5fzpA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5msw THIOESTER REDUCTASE
DOMAIN-CONTAINING
PROTEIN

(Segniliparus
rugosus) 		PF00501
(AMP-binding)
PF00550
(PP-binding) 		4 VAL A  87
VAL A 207
THR A  83
ARG A 204
 None
 1.29A 3bjwD-5mswA:
undetectable		 3bjwD-5mswA:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nxn PORIN 1

(Providencia
stuartii) 		no annotation 4 VAL A 101
VAL A 100
THR A 249
THR A 104
 None
 1.12A 3bjwD-5nxnA:
undetectable		 3bjwD-5nxnA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o32 COMPLEMENT FACTOR I

(Homo sapiens) 		PF00089
(Trypsin) 		4 VAL I 540
VAL I 454
THR I 377
THR I 538
 None
 1.24A 3bjwD-5o32I:
undetectable		 3bjwD-5o32I:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5odr METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
A

(Methanothermococcus
thermolithotrophicus) 		PF00374
(NiFeSe_Hases) 		4 VAL F 397
VAL F 396
THR F  57
THR F 399
 NFU  F 501 (-4.4A)
None
None
NFU  F 501 (-3.7A)
 1.14A 3bjwD-5odrF:
undetectable		 3bjwD-5odrF:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5odr METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
A
METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
G

(Methanothermococcus
thermolithotrophicus) 		PF00374
(NiFeSe_Hases)
PF01058
(Oxidored_q6) 		4 VAL F 396
VAL F 397
THR E 114
THR F 377
 None
NFU  F 501 (-4.4A)
None
None
 1.24A 3bjwD-5odrF:
undetectable		 3bjwD-5odrF:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opf CHITIN-BINDING
DOMAIN 3 PROTEIN

(Micromonospora
aurantiaca) 		no annotation 4 VAL A 208
VAL A 153
THR A 127
THR A 210
 None
 1.21A 3bjwD-5opfA:
undetectable		 3bjwD-5opfA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t5w INTERFERON LAMBDA
RECEPTOR 1

(Homo sapiens) 		PF01108
(Tissue_fac) 		4 VAL B  80
VAL B  37
THR B  11
THR B  82
 None
 1.14A 3bjwD-5t5wB:
undetectable		 3bjwD-5t5wB:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tpk PROTOCADHERIN-15

(Mus musculus) 		no annotation 4 VAL A 805
VAL A 806
THR A 815
THR A 892
 None
 1.29A 3bjwD-5tpkA:
undetectable		 3bjwD-5tpkA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vqi IMPORTIN SUBUNIT
ALPHA

(Neurospora
crassa) 		no annotation 4 VAL B 161
VAL B 162
THR B 123
THR B 157
 None
 1.15A 3bjwD-5vqiB:
undetectable		 3bjwD-5vqiB:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y0s THERMOTOGA MARITIMA
TMCAL

(Thermotoga
maritima) 		no annotation 4 VAL A  66
VAL A  67
THR A  93
THR A 343
 None
 1.19A 3bjwD-5y0sA:
undetectable		 3bjwD-5y0sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gnf -

(-) 		no annotation 4 VAL A   7
VAL A  41
THR A 176
THR A   9
 None
 1.16A 3bjwD-6gnfA:
1.4		 3bjwD-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1as4 ANTICHYMOTRYPSIN

(Homo sapiens) 		PF00079
(Serpin) 		4 VAL A 183
ILE A 321
GLY A 320
ARG A 325
 None
 0.83A 3bjwH-1as4A:
undetectable		 3bjwH-1as4A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bgc GRANULOCYTE
COLONY-STIMULATING
FACTOR

(Bos taurus) 		PF16647
(GCSF) 		4 GLN A 146
GLY A 150
ARG A 148
LEU A  36
 None
 0.91A 3bjwH-1bgcA:
undetectable		 3bjwH-1bgcA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bru ELASTASE

(Sus scrofa) 		PF00089
(Trypsin) 		4 VAL P  90
ILE P 212
GLY P 211
ARG P 230
 None
 0.78A 3bjwH-1bruP:
undetectable		 3bjwH-1bruP:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itk CATALASE-PEROXIDASE

(Haloarcula
marismortui) 		PF00141
(peroxidase) 		4 VAL A 716
ILE A 624
GLY A 625
ARG A 585
 None
 0.83A 3bjwH-1itkA:
0.0		 3bjwH-1itkA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kkr 3-METHYLASPARTATE
AMMONIA-LYASE

(Citrobacter
amalonaticus) 		PF05034
(MAAL_N)
PF07476
(MAAL_C) 		4 VAL A 317
ILE A 330
GLY A 358
ARG A 382
 None
 0.78A 3bjwH-1kkrA:
undetectable		 3bjwH-1kkrA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lwu FIBRINOGEN BETA
CHAIN

(Petromyzon
marinus) 		PF00147
(Fibrinogen_C)
PF08702
(Fib_alpha) 		4 VAL B 319
ILE B 248
GLY B 229
ARG B 237
 None
 0.79A 3bjwH-1lwuB:
undetectable		 3bjwH-1lwuB:
14.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mc2 ACUTOHAEMONLYSIN

(Deinagkistrodon
acutus) 		PF00068
(Phospholip_A2_1) 		4 GLN A1011
GLY A1014
ARG A1107
LEU A1110
 None
 0.23A 3bjwH-1mc2A:
21.1		 3bjwH-1mc2A:
56.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pyt CHYMOTRYPSINOGEN C

(Bos taurus) 		PF00089
(Trypsin) 		4 VAL D 790
ILE D 912
GLY D 911
ARG D 930
 None
 0.67A 3bjwH-1pytD:
undetectable		 3bjwH-1pytD:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)

(Homo sapiens) 		PF00753
(Lactamase_B)
PF16123
(HAGH_C) 		4 VAL A 130
ILE A 115
GLY A  78
LEU A  85
 None
 0.82A 3bjwH-1qh5A:
undetectable		 3bjwH-1qh5A:
17.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1s8h PHOSPHOLIPASE A2
HOMOLOG

(Agkistrodon
contortrix) 		PF00068
(Phospholip_A2_1) 		4 GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.41A 3bjwH-1s8hA:
20.4		 3bjwH-1s8hA:
62.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w99 PESTICIDIAL CRYSTAL
PROTEIN CRY4BA

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 VAL A 214
LYS A 218
ILE A 221
LEU A 175
 None
 0.57A 3bjwH-1w99A:
undetectable		 3bjwH-1w99A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xwm PHOSPHATE UPTAKE
REGULATOR

(Geobacillus
stearothermophilus) 		PF01895
(PhoU) 		4 VAL A  98
LYS A 102
ILE A 105
GLY A 108
 None
 0.75A 3bjwH-1xwmA:
1.5		 3bjwH-1xwmA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 ILE A1037
GLN A  10
GLY A1038
LEU A1000
 None
 0.57A 3bjwH-2b5mA:
undetectable		 3bjwH-2b5mA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bdv PHAGE-RELATED
CONSERVED
HYPOTHETICAL
PROTEIN, BB2244

(Bordetella
bronchiseptica) 		PF02586
(SRAP) 		4 VAL A  49
ILE A  95
GLY A 131
LEU A 191
 None
 0.59A 3bjwH-2bdvA:
undetectable		 3bjwH-2bdvA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1h DELTA-AMINOLEVULINIC
ACID DEHYDRATASE

(Prosthecochloris
vibrioformis) 		PF00490
(ALAD) 		4 VAL A  67
LYS A  71
GLY A  77
ARG A 328
 None
 0.90A 3bjwH-2c1hA:
undetectable		 3bjwH-2c1hA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fff PENICILLIN-BINDING
PROTEIN 1B

(Streptococcus
pneumoniae) 		PF00905
(Transpeptidase) 		4 ILE B 470
GLN B 474
GLY B 469
LEU B 509
 None
 0.72A 3bjwH-2fffB:
undetectable		 3bjwH-2fffB:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fvl ALDO-KETO REDUCTASE
FAMILY 1, MEMBER C4

(Homo sapiens) 		PF00248
(Aldo_ket_red) 		4 VAL A  35
LYS A  39
ILE A  42
GLY A  45
 None
 0.85A 3bjwH-2fvlA:
undetectable		 3bjwH-2fvlA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ipc PREPROTEIN
TRANSLOCASE SECA
SUBUNIT

(Thermus
thermophilus) 		PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD) 		4 VAL A 432
ILE A 544
GLY A 543
ARG A 541
 None
 0.78A 3bjwH-2ipcA:
undetectable		 3bjwH-2ipcA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j5b TYROSYL-TRNA
SYNTHETASE

(Acanthamoeba
polyphaga
mimivirus) 		PF00579
(tRNA-synt_1b) 		4 ILE A  30
GLN A  64
GLY A  62
LEU A   8
 ILE  A  30 ( 0.7A)
GLN  A  64 ( 0.6A)
GLY  A  62 ( 0.0A)
LEU  A   8 ( 0.6A)
 0.92A 3bjwH-2j5bA:
undetectable		 3bjwH-2j5bA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p7s AMPHINASE-2

(Rana pipiens) 		PF00074
(RnaseA) 		4 VAL A  66
LYS A  68
GLY A 112
LEU A  76
 None
 0.86A 3bjwH-2p7sA:
undetectable		 3bjwH-2p7sA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I

(Escherichia
coli) 		PF00365
(PFK) 		4 VAL A 202
LYS A 206
ILE A 209
GLY A 212
 None
 0.77A 3bjwH-2pfkA:
undetectable		 3bjwH-2pfkA:
15.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ph4 ZHAOERMIATOXIN

(Protobothrops
mangshanensis) 		PF00068
(Phospholip_A2_1) 		4 GLN A  11
GLY A  15
ARG A 107
LEU A 110
 None
 0.50A 3bjwH-2ph4A:
19.3		 3bjwH-2ph4A:
57.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q1d 2-KETO-3-DEOXY-D-ARA
BINONATE DEHYDRATASE

(Sulfolobus
solfataricus) 		PF01557
(FAA_hydrolase) 		4 VAL X 148
ILE X 279
GLY X 280
LEU X  57
 None
 0.86A 3bjwH-2q1dX:
undetectable		 3bjwH-2q1dX:
16.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		6 VAL A   3
ILE A  10
GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.59A 3bjwH-2qheA:
23.8		 3bjwH-2qheA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vgi PYRUVATE KINASE
ISOZYMES R/L

(Homo sapiens) 		PF00224
(PK)
PF02887
(PK_C) 		4 VAL A 101
LYS A 105
ILE A 108
GLY A 111
 None
 0.90A 3bjwH-2vgiA:
undetectable		 3bjwH-2vgiA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y7c TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN

(Escherichia
coli) 		PF02384
(N6_Mtase)
PF12161
(HsdM_N) 		4 VAL B  89
ILE B 244
GLY B 214
LEU B 257
 None
 0.85A 3bjwH-2y7cB:
undetectable		 3bjwH-2y7cB:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1

(Homo sapiens) 		PF02732
(ERCC4) 		4 VAL B 501
ILE B 545
GLY B 546
ARG B 551
 None
 0.80A 3bjwH-2ziuB:
undetectable		 3bjwH-2ziuB:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a4t PUTATIVE
METHYLTRANSFERASE
MJ0026

(Methanocaldococcus
jannaschii) 		PF01189
(Methyltr_RsmB-F) 		4 VAL A  35
ILE A  54
GLY A  55
LEU A  61
 None
 0.90A 3bjwH-3a4tA:
undetectable		 3bjwH-3a4tA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aib GLUCOSYLTRANSFERASE-
SI

(Streptococcus
mutans) 		PF02324
(Glyco_hydro_70) 		4 VAL A 752
ILE A 707
GLY A 738
LEU A 642
 None
 0.87A 3bjwH-3aibA:
undetectable		 3bjwH-3aibA:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dh9 THIOREDOXIN
REDUCTASE 1

(Drosophila
melanogaster) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 VAL A 155
ILE A 327
GLY A 289
ARG A 161
 None
 0.90A 3bjwH-3dh9A:
undetectable		 3bjwH-3dh9A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e9y ACETOLACTATE
SYNTHASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 VAL A 545
ILE A 521
GLY A 522
ARG A 156
 None
 0.92A 3bjwH-3e9yA:
undetectable		 3bjwH-3e9yA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3exh PYRUVATE
DEHYDROGENASE E1
COMPONENT SUBUNIT
BETA, MITOCHONDRIAL

(Homo sapiens) 		PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 VAL B 168
ILE B 157
GLY B  12
ARG B  19
 None
 0.92A 3bjwH-3exhB:
undetectable		 3bjwH-3exhB:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fb4 ADENYLATE KINASE

(Jeotgalibacillus
marinus) 		PF00406
(ADK)
PF05191
(ADK_lid) 		4 VAL A  90
ILE A  65
GLY A  66
LEU A  45
 None
 0.80A 3bjwH-3fb4A:
undetectable		 3bjwH-3fb4A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6r DIHYDROOROTATE
DEHYDROGENASE
HOMOLOG,
MITOCHONDRIAL

(Plasmodium
falciparum) 		PF01180
(DHO_dh) 		4 VAL A 322
LYS A 326
ILE A 329
GLY A 333
 None
 0.82A 3bjwH-3i6rA:
undetectable		 3bjwH-3i6rA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k70 EXODEOXYRIBONUCLEASE
V ALPHA CHAIN

(Escherichia
coli) 		PF13538
(UvrD_C_2)
PF13604
(AAA_30) 		4 VAL D 268
ILE D 199
ARG D 232
LEU D 225
 None
 0.85A 3bjwH-3k70D:
undetectable		 3bjwH-3k70D:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kgw ALANINE-GLYOXYLATE
AMINOTRANSFERASE

(Mus musculus) 		PF00266
(Aminotran_5) 		4 LYS A  83
ILE A  86
GLN A  87
LEU A 306
 None
 0.88A 3bjwH-3kgwA:
undetectable		 3bjwH-3kgwA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kkj AMINE OXIDASE,
FLAVIN-CONTAINING

(Pseudomonas
syringae group
genomosp. 3) 		PF01593
(Amino_oxidase)
PF13450
(NAD_binding_8) 		4 VAL A  69
ILE A  12
ARG A 117
LEU A  30
 None
 0.87A 3bjwH-3kkjA:
undetectable		 3bjwH-3kkjA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kkj AMINE OXIDASE,
FLAVIN-CONTAINING

(Pseudomonas
syringae group
genomosp. 3) 		PF01593
(Amino_oxidase)
PF13450
(NAD_binding_8) 		4 VAL A  69
ILE A  12
GLY A  11
ARG A 117
 None
None
FAD  A 401 (-2.9A)
None
 0.93A 3bjwH-3kkjA:
undetectable		 3bjwH-3kkjA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l7z PROBABLE EXOSOME
COMPLEX RNA-BINDING
PROTEIN 1

(Sulfolobus
solfataricus) 		no annotation 4 VAL C 188
ILE C 127
GLY C 149
LEU C 120
 None
 0.88A 3bjwH-3l7zC:
undetectable		 3bjwH-3l7zC:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1c ENVELOPE
GLYCOPROTEIN L

(Human
alphaherpesvirus
2) 		PF05259
(Herpes_UL1)
PF12524
(GlyL_C) 		4 VAL B  61
ILE B  67
GLY B  69
ARG B  86
 None
 0.90A 3bjwH-3m1cB:
undetectable		 3bjwH-3m1cB:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qkw NUCLEOTIDE SUGAR
SYNTHETASE-LIKE
PROTEIN

(Streptococcus
parasanguinis) 		no annotation 4 VAL A  27
ILE A  69
GLN A  71
LEU A  62
 None
 0.67A 3bjwH-3qkwA:
undetectable		 3bjwH-3qkwA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s4w FANCONI ANEMIA GROUP
D2 PROTEIN HOMOLOG

(Mus musculus) 		PF14631
(FancD2) 		4 VAL B 565
GLN B 560
GLY B 575
LEU B 611
 None
 0.85A 3bjwH-3s4wB:
undetectable		 3bjwH-3s4wB:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ssm METHYLTRANSFERASE

(Micromonospora
griseorubida) 		no annotation 4 VAL A  16
GLN A 229
GLY A 267
ARG A 265
 None
 0.79A 3bjwH-3ssmA:
undetectable		 3bjwH-3ssmA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3suc PRENECK APPENDAGE
PROTEIN

(Bacillus virus
phi29) 		PF11962
(Peptidase_G2)
PF12708
(Pectate_lyase_3) 		4 VAL A 382
ILE A 332
GLY A 331
ARG A 358
 None
 0.90A 3bjwH-3sucA:
undetectable		 3bjwH-3sucA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
UBIQUITIN-LIKE
PROTEIN
SMT3,RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Saccharomyces
cerevisiae;
Schizosaccharomyces
pombe) 		PF11976
(Rad60-SLD)
no annotation 		4 VAL A  66
ILE A   6
GLY A   7
LEU B 655
 None
CL  A1003 (-4.1A)
None
None
 0.69A 3bjwH-3tixA:
undetectable		 3bjwH-3tixA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN

(Streptococcus
pyogenes) 		PF09704
(Cas_Cas5d) 		4 VAL A  94
ILE A  43
GLY A  42
ARG A  37
 None
 0.80A 3bjwH-3vzhA:
undetectable		 3bjwH-3vzhA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE

(Archaeoglobus
fulgidus) 		PF02516
(STT3) 		4 VAL A 624
ILE A 574
GLY A 573
LEU A 603
 None
 0.69A 3bjwH-3wajA:
2.4		 3bjwH-3wajA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wwy D-LACTATE
DEHYDROGENASE

(Fusobacterium
nucleatum) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 VAL A 112
ILE A 231
GLY A 256
LEU A 250
 None
None
GOL  A 405 ( 3.8A)
None
 0.78A 3bjwH-3wwyA:
undetectable		 3bjwH-3wwyA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyy IRON-SULFUR CLUSTER
BINDING PROTEIN

(Carboxydothermus
hydrogenoformans) 		PF00111
(Fer2)
PF14574
(DUF4445) 		4 VAL X 487
ILE X 461
GLY X 460
ARG X 458
 None
 0.86A 3bjwH-3zyyX:
undetectable		 3bjwH-3zyyX:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aej COLLAGEN
ALPHA-1(III) CHAIN

(Homo sapiens) 		PF01410
(COLFI) 		4 VAL A 207
ILE A 220
GLY A 173
ARG A 217
 GOL  A1248 ( 4.4A)
None
None
None
 0.92A 3bjwH-4aejA:
undetectable		 3bjwH-4aejA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4av6 K(+)-STIMULATED
PYROPHOSPHATE-ENERGI
ZED SODIUM PUMP

(Thermotoga
maritima) 		PF03030
(H_PPase) 		4 VAL A 698
ILE A 503
GLY A 504
LEU A 448
 None
 0.72A 3bjwH-4av6A:
1.0		 3bjwH-4av6A:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cr6 N-ACYLMANNOSAMINE
1-DEHYDROGENASE

(Flavobacterium
sp. 141-8) 		PF13561
(adh_short_C2) 		4 VAL A 154
ILE A 151
GLY A  94
LEU A  68
 None
 0.82A 3bjwH-4cr6A:
undetectable		 3bjwH-4cr6A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h4f CHYMOTRYPSIN-C

(Homo sapiens) 		PF00089
(Trypsin) 		4 VAL A  90
ILE A 212
GLY A 211
ARG A 230
 None
 0.80A 3bjwH-4h4fA:
undetectable		 3bjwH-4h4fA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hou INTERFERON-INDUCED
PROTEIN WITH
TETRATRICOPEPTIDE
REPEATS 1

(Homo sapiens) 		PF13181
(TPR_8)
PF13424
(TPR_12) 		4 VAL A 221
ILE A 183
GLY A 180
LEU A 168
 None
 0.90A 3bjwH-4houA:
undetectable		 3bjwH-4houA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i0p HLA CLASS II
HISTOCOMPATIBILITY
ANTIGEN, DO ALPHA
CHAIN
HLA CLASS II
HISTOCOMPATIBILITY
ANTIGEN, DO BETA
CHAIN

(Homo sapiens) 		PF00969
(MHC_II_beta)
PF00993
(MHC_II_alpha)
PF07654
(C1-set) 		4 VAL C  91
ILE D 148
GLN D 156
GLY D 146
 None
 0.91A 3bjwH-4i0pC:
undetectable		 3bjwH-4i0pC:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iss ALLOPHANATE
HYDROLASE

(Kluyveromyces
lactis) 		PF01425
(Amidase) 		5 VAL A 538
LYS A 520
ILE A 546
GLY A 605
LEU A 493
 None
 1.47A 3bjwH-4issA:
undetectable		 3bjwH-4issA:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4it4 CG17282

(Drosophila
melanogaster) 		no annotation 4 VAL A 158
LYS A 162
ILE A 165
LEU A 173
 None
 0.59A 3bjwH-4it4A:
undetectable		 3bjwH-4it4A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jnh GAG POLYPROTEIN

(Simian foamy
virus) 		PF03276
(Gag_spuma) 		4 VAL A  18
ILE A  36
GLY A  37
ARG A  39
 None
 0.87A 3bjwH-4jnhA:
undetectable		 3bjwH-4jnhA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m9x CELL DEATH PROTEIN 4

(Caenorhabditis
elegans) 		PF00619
(CARD)
PF00931
(NB-ARC) 		4 VAL A 248
ILE A 180
GLY A 181
ARG A 102
 None
 0.72A 3bjwH-4m9xA:
undetectable		 3bjwH-4m9xA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Methanocaldococcus
jannaschii) 		PF02350
(Epimerase_2) 		4 VAL A  90
ILE A  19
GLY A 354
ARG A 356
 None
 0.91A 3bjwH-4nesA:
undetectable		 3bjwH-4nesA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4omj SEC14-LIKE PROTEIN 2

(Homo sapiens) 		PF00650
(CRAL_TRIO) 		4 VAL A 239
ILE A 258
GLY A  87
LEU A 131
 None
 0.81A 3bjwH-4omjA:
undetectable		 3bjwH-4omjA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p6v NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT A

(Vibrio cholerae) 		PF05896
(NQRA)
PF11973
(NQRA_SLBB) 		4 VAL A 165
ILE A 245
GLN A 242
LEU A 181
 None
 0.86A 3bjwH-4p6vA:
undetectable		 3bjwH-4p6vA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2c CRISPR-ASSOCIATED
HELICASE CAS3

(Thermobaculum
terrenum) 		PF00271
(Helicase_C) 		4 VAL A 845
ILE A 939
GLY A 938
LEU A 627
 None
 0.84A 3bjwH-4q2cA:
2.2		 3bjwH-4q2cA:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rnw NADPH DEHYDROGENASE
1

(Saccharomyces
pastorianus) 		PF00724
(Oxidored_FMN) 		4 VAL A 273
LYS A 277
ILE A 280
GLY A 283
 None
 0.89A 3bjwH-4rnwA:
undetectable		 3bjwH-4rnwA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rnx NADPH DEHYDROGENASE
1

(Saccharomyces
pastorianus) 		PF00724
(Oxidored_FMN) 		4 VAL A  23
LYS A  27
ILE A  30
GLY A  33
 None
 0.83A 3bjwH-4rnxA:
undetectable		 3bjwH-4rnxA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tmc OLD YELLOW ENZYME

(Kluyveromyces
marxianus) 		PF00724
(Oxidored_FMN) 		4 VAL A 174
LYS A 178
ILE A 181
GLY A 184
 None
 0.85A 3bjwH-4tmcA:
undetectable		 3bjwH-4tmcA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u9o NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT A

(Vibrio cholerae) 		PF05896
(NQRA)
PF11973
(NQRA_SLBB) 		4 VAL A 165
ILE A 245
GLN A 242
LEU A 181
 None
 0.88A 3bjwH-4u9oA:
undetectable		 3bjwH-4u9oA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uuo CYTOSOLIC MALATE
DEHYDROGENASE

(Trichomonas
vaginalis) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		5 VAL A  85
ILE A 106
GLN A 110
GLY A 105
LEU A 330
 None
 0.90A 3bjwH-4uuoA:
undetectable		 3bjwH-4uuoA:
15.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1

(Bothrops
jararacussu) 		PF00068
(Phospholip_A2_1) 		4 GLN A  11
GLY A  14
ARG A  97
LEU A 100
 None
 0.37A 3bjwH-4wtbA:
21.3		 3bjwH-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1

(Bothrops
jararacussu) 		PF00068
(Phospholip_A2_1) 		4 LYS A   7
GLY A  14
ARG A  97
LEU A 100
 None
 0.71A 3bjwH-4wtbA:
21.3		 3bjwH-4wtbA:
56.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ybq SOLUTE CARRIER
FAMILY 2,
FACILITATED GLUCOSE
TRANSPORTER MEMBER 5

(Rattus
norvegicus) 		PF00083
(Sugar_tr) 		4 VAL A 144
ILE A 398
ARG A 340
LEU A 344
 None
 0.89A 3bjwH-4ybqA:
0.7		 3bjwH-4ybqA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yd8 PROTEIN PTHB1

(Homo sapiens) 		PF14727
(PHTB1_N) 		4 VAL A 318
ILE A 305
GLY A 306
LEU A 326
 None
 0.87A 3bjwH-4yd8A:
undetectable		 3bjwH-4yd8A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ync NADPH DEHYDROGENASE
1

(Saccharomyces
pastorianus) 		PF00724
(Oxidored_FMN) 		4 VAL A 174
LYS A 178
ILE A 181
GLY A 184
 None
 0.86A 3bjwH-4yncA:
undetectable		 3bjwH-4yncA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z0t OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY

(Brucella ovis) 		PF00106
(adh_short) 		4 VAL A  34
ILE A  78
GLY A  76
ARG A  73
 None
 0.88A 3bjwH-4z0tA:
undetectable		 3bjwH-4z0tA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA

(Escherichia
coli) 		PF02917
(Pertussis_S1) 		4 VAL A  10
ILE A 130
GLY A 127
ARG A  20
 NAD  A 202 (-4.1A)
None
None
None
 0.92A 3bjwH-4z9dA:
undetectable		 3bjwH-4z9dA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zqi D-ALANINE--D-ALANINE
LIGASE

(Yersinia pestis) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 VAL A 115
ILE A 111
GLN A 105
LEU A 248
 None
 0.94A 3bjwH-4zqiA:
undetectable		 3bjwH-4zqiA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ay9 4-O-BETA-D-MANNOSYL-
D-GLUCOSE
PHOSPHORYLASE

(Ruminococcus
albus) 		PF04041
(Glyco_hydro_130) 		4 VAL A 232
ILE A 164
GLY A 142
ARG A 131
 None
 0.70A 3bjwH-5ay9A:
undetectable		 3bjwH-5ay9A:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b47 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT

(Sulfurisphaera
tokodaii) 		PF02775
(TPP_enzyme_C)
PF12367
(PFO_beta_C) 		4 VAL B  84
ILE B  33
GLY B  32
ARG B  29
 None
 0.75A 3bjwH-5b47B:
undetectable		 3bjwH-5b47B:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cju ISOBUTYRYL-COA
MUTASE FUSED

(Cupriavidus
metallidurans) 		PF01642
(MM_CoA_mutase)
PF02310
(B12-binding)
PF03308
(ArgK) 		4 VAL A  91
LYS A  95
ILE A  98
LEU A  74
 None
 0.75A 3bjwH-5cjuA:
undetectable		 3bjwH-5cjuA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d1l E3 UBIQUITIN-PROTEIN
LIGASE RNF25

(Homo sapiens) 		PF17123
(zf-RING_11) 		4 ILE B 251
GLN B 246
GLY B 250
ARG B 244
 None
 0.92A 3bjwH-5d1lB:
undetectable		 3bjwH-5d1lB:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5elx ATP-DEPENDENT RNA
HELICASE DBP5

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 VAL A 299
ILE A 304
GLN A 306
GLY A 434
 None
 0.73A 3bjwH-5elxA:
undetectable		 3bjwH-5elxA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fcl CRISPR-ASSOCIATED
ENDONUCLEASE CAS1

(Pectobacterium
atrosepticum) 		PF01867
(Cas_Cas1) 		4 VAL A 140
GLN A 175
GLY A 177
ARG A 173
 None
 0.89A 3bjwH-5fclA:
undetectable		 3bjwH-5fclA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fqd DNA DAMAGE-BINDING
PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 ILE A1037
GLN A  10
GLY A1038
LEU A1000
 None
 0.59A 3bjwH-5fqdA:
undetectable		 3bjwH-5fqdA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i8i UREA AMIDOLYASE

(Kluyveromyces
lactis) 		PF00289
(Biotin_carb_N)
PF01425
(Amidase)
PF02626
(CT_A_B)
PF02682
(CT_C_D)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		5 VAL A 538
LYS A 520
ILE A 546
GLY A 605
LEU A 493
 None
 1.46A 3bjwH-5i8iA:
undetectable		 3bjwH-5i8iA:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jw6 ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Aspergillus
fumigatus) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 VAL A 156
ILE A 344
GLY A 314
ARG A 309
 None
 0.83A 3bjwH-5jw6A:
undetectable		 3bjwH-5jw6A:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k3w CPUTA1

(Curtobacterium
pusillum) 		PF01063
(Aminotran_4) 		4 VAL A 199
ILE A 230
GLN A 228
LEU A  82
 None
 0.90A 3bjwH-5k3wA:
undetectable		 3bjwH-5k3wA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kl0 PHOSPHOGLUCOMUTASE

(Xanthomonas
citri) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 ILE A 393
GLY A 391
ARG A 302
LEU A 303
 None
None
G16  A 501 ( 3.6A)
None
 0.93A 3bjwH-5kl0A:
undetectable		 3bjwH-5kl0A:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lir SIGMA CROSS-REACTING
PROTEIN 27A
(SCRP-27A)

(Salmonella
enterica) 		PF01965
(DJ-1_PfpI) 		4 VAL A 217
ILE A   7
GLY A   8
LEU A 123
 None
 0.91A 3bjwH-5lirA:
undetectable		 3bjwH-5lirA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lm8 'MULTICOPPER OXIDASE

(Aspergillus
niger) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 140
ILE A  84
GLY A 166
ARG A 290
 None
 0.82A 3bjwH-5lm8A:
undetectable		 3bjwH-5lm8A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lrb ALPHA-1,4 GLUCAN
PHOSPHORYLASE

(Hordeum vulgare) 		PF00343
(Phosphorylase) 		4 VAL A 272
LYS A 270
ILE A 269
LEU A 440
 None
 0.91A 3bjwH-5lrbA:
undetectable		 3bjwH-5lrbA:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5npr UDP-N-ACETYLGLUCOSAM
INE--PEPTIDE
N-ACETYLGLUCOSAMINYL
TRANSFERASE 110 KDA
SUBUNIT

(Homo sapiens) 		no annotation 4 ILE A 876
GLN A 877
GLY A 872
ARG A 867
 None
 0.90A 3bjwH-5nprA:
undetectable		 3bjwH-5nprA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nth PUTATIVE
AMINOPEPTIDASE

(Leishmania
major) 		PF00883
(Peptidase_M17) 		4 VAL A 278
ILE A 264
GLY A 263
ARG A 257
 None
 0.82A 3bjwH-5nthA:
undetectable		 3bjwH-5nthA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tuc SUS TBC1D15 GAP
DOMAIN

(Sus scrofa) 		PF00566
(RabGAP-TBC) 		4 VAL A 318
LYS A 322
ILE A 325
GLY A 329
 None
 0.72A 3bjwH-5tucA:
undetectable		 3bjwH-5tucA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udb DNA REPLICATION
LICENSING FACTOR
MCM6

(Saccharomyces
cerevisiae) 		PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB) 		4 VAL 6 589
ILE 6 547
GLY 6 546
LEU 6 806
 None
 0.75A 3bjwH-5udb6:
undetectable		 3bjwH-5udb6:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w3w ARYLDIALKYLPHOSPHATA
SE

(Sulfolobus
solfataricus) 		no annotation 4 VAL A  50
LYS A  54
GLN A  58
GLY A  60
 None
 0.69A 3bjwH-5w3wA:
undetectable		 3bjwH-5w3wA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wcj METHYLTRANSFERASE-LI
KE PROTEIN 13

(Homo sapiens) 		PF01564
(Spermine_synth) 		4 VAL A 500
ILE A 612
GLY A 480
LEU A 672
 None
 0.89A 3bjwH-5wcjA:
undetectable		 3bjwH-5wcjA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2

(Homo sapiens) 		no annotation 4 VAL A   3
GLY A  14
ARG A  98
LEU A 101
 None
None
None
TRS  A 211 (-4.0A)
 0.52A 3bjwH-5wzmA:
20.3		 3bjwH-5wzmA:
29.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		no annotation 4 VAL A 496
ILE A 523
GLY A 524
ARG A 527
 None
 0.87A 3bjwH-5ze4A:
undetectable		 3bjwH-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ce2 -

(-) 		no annotation 4 VAL A   3
GLN A  11
GLY A  15
ARG A 107
 None
 0.66A 3bjwH-6ce2A:
20.5		 3bjwH-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fnu METHYLENETETRAHYDROF
OLATE REDUCTASE 1

(Saccharomyces
cerevisiae) 		no annotation 4 VAL A 262
ILE A 269
GLN A 270
LEU A 198
 None
 0.75A 3bjwH-6fnuA:
undetectable		 3bjwH-6fnuA:
13.93