SIMILAR PATTERNS OF AMINO ACIDS FOR 3BJW_G_SVRG506_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
16vp PROTEIN (VP16,
VMW65, ATIF)

(Human
alphaherpesvirus
1) 		PF02232
(Alpha_TIF) 		4 VAL A 112
VAL A 113
GLY A 116
ARG A 208
 None
 0.82A 3bjwA-16vpA:
undetectable		 3bjwA-16vpA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bgp BARLEY GRAIN
PEROXIDASE

(Hordeum vulgare) 		PF00141
(peroxidase) 		4 VAL A 120
VAL A 119
GLY A 122
ARG A  26
 None
 0.85A 3bjwA-1bgpA:
0.1		 3bjwA-1bgpA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bgp BARLEY GRAIN
PEROXIDASE

(Hordeum vulgare) 		PF00141
(peroxidase) 		4 VAL A 279
GLY A 282
LYS A 283
PRO A 129
 None
 0.83A 3bjwA-1bgpA:
0.1		 3bjwA-1bgpA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bsz PROTEIN (PEPTIDE
DEFORMYLASE)

(Escherichia
coli) 		PF01327
(Pep_deformylase) 		4 VAL A  16
VAL A 138
GLY A 139
ARG A  56
 None
 0.95A 3bjwA-1bszA:
undetectable		 3bjwA-1bszA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c4o DNA NUCLEOTIDE
EXCISION REPAIR
ENZYME UVRB

(Thermus
thermophilus) 		PF00271
(Helicase_C)
PF04851
(ResIII)
PF12344
(UvrB) 		4 VAL A  44
GLY A  41
PRO A 409
LYS A  48
 None
SO4  A9001 (-3.5A)
None
None
 0.98A 3bjwA-1c4oA:
undetectable		 3bjwA-1c4oA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dd5 RIBOSOME RECYCLING
FACTOR

(Thermotoga
maritima) 		PF01765
(RRF) 		4 VAL A 121
GLY A 124
LYS A 125
LYS A 116
 None
 0.97A 3bjwA-1dd5A:
2.1		 3bjwA-1dd5A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f81 CREB-BINDING PROTEIN

(Mus musculus) 		PF02135
(zf-TAZ) 		4 VAL A  39
VAL A  40
LYS A  44
LYS A  35
 None
 0.93A 3bjwA-1f81A:
undetectable		 3bjwA-1f81A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gcw PROTEIN (HEMOGLOBIN)

(Mustelus
griseus) 		PF00042
(Globin) 		4 VAL A  57
GLY A  60
LYS A  61
PRO A  21
 None
 0.92A 3bjwA-1gcwA:
0.2		 3bjwA-1gcwA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k7y METHIONINE SYNTHASE

(Escherichia
coli) 		PF02310
(B12-binding)
PF02607
(B12-binding_2)
PF02965
(Met_synt_B12) 		4 VAL A 668
GLY A 700
LYS A 669
LYS A 726
 None
 0.94A 3bjwA-1k7yA:
0.0		 3bjwA-1k7yA:
11.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mc2 ACUTOHAEMONLYSIN

(Deinagkistrodon
acutus) 		PF00068
(Phospholip_A2_1) 		4 GLY A1006
LYS A1007
PRO A1017
ARG A1072
 IPA  A1136 (-3.6A)
None
IPA  A1136 (-4.4A)
None
 0.96A 3bjwA-1mc2A:
20.1		 3bjwA-1mc2A:
56.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nu2 DISABLED HOMOLOG 1

(Mus musculus) 		PF00640
(PID) 		4 VAL A  71
VAL A  72
GLY A  74
LYS A  67
 None
 0.86A 3bjwA-1nu2A:
undetectable		 3bjwA-1nu2A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rpu 19 KDA PROTEIN

(Carnation
Italian
ringspot virus) 		PF03220
(Tombus_P19) 		5 VAL A  68
VAL A  69
LYS A  71
PRO A  29
ARG A  11
 None
C  C  10 ( 4.8A)
A  C  11 ( 2.9A)
None
C  C  10 ( 2.7A)
 1.41A 3bjwA-1rpuA:
undetectable		 3bjwA-1rpuA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vp4 AMINOTRANSFERASE,
PUTATIVE

(Thermotoga
maritima) 		PF00155
(Aminotran_1_2) 		4 VAL A 403
GLY A 407
LYS A 408
ARG A 400
 None
None
None
FMT  A 620 ( 3.5A)
 0.83A 3bjwA-1vp4A:
undetectable		 3bjwA-1vp4A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y3n ALGQ1

(Sphingomonas
sp. A1) 		PF01547
(SBP_bac_1) 		4 VAL A  35
GLY A 341
LYS A 340
ARG A  37
 None
 0.96A 3bjwA-1y3nA:
undetectable		 3bjwA-1y3nA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y4c MALTOSE BINDING
PROTEIN FUSED WITH
DESIGNED HELICAL
PROTEIN

(Escherichia
coli) 		PF13416
(SBP_bac_8) 		4 VAL A 110
GLY A 300
PRO A 229
LYS A 305
 None
 0.93A 3bjwA-1y4cA:
undetectable		 3bjwA-1y4cA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yt5 INORGANIC
POLYPHOSPHATE/ATP-NA
D KINASE

(Thermotoga
maritima) 		PF01513
(NAD_kinase) 		4 VAL A 203
VAL A 202
LYS A 200
ARG A 223
 None
 0.89A 3bjwA-1yt5A:
undetectable		 3bjwA-1yt5A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bdz MEXICAIN

(Jacaratia
mexicana) 		PF00112
(Peptidase_C1) 		4 VAL A 105
VAL A  80
GLY A  79
LYS A 100
 None
 0.96A 3bjwA-2bdzA:
undetectable		 3bjwA-2bdzA:
26.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l4v CYSTATIN

(Ananas comosus) 		PF16845
(SQAPI) 		4 VAL A  90
VAL A  91
GLY A  93
LYS A 114
 None
 0.90A 3bjwA-2l4vA:
undetectable		 3bjwA-2l4vA:
17.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		5 VAL A   2
VAL A   3
GLY A   6
PRO A  18
ARG A  72
 None
 1.36A 3bjwA-2qheA:
22.8		 3bjwA-2qheA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vdc GLUTAMATE SYNTHASE
[NADPH] LARGE CHAIN

(Azospirillum
brasilense) 		PF00310
(GATase_2)
PF01493
(GXGXG)
PF01645
(Glu_synthase)
PF04898
(Glu_syn_central) 		4 VAL A  17
VAL A  18
GLY A  21
ARG A  15
 None
 0.89A 3bjwA-2vdcA:
undetectable		 3bjwA-2vdcA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wyo GLUTATHIONE
SYNTHETASE

(Trypanosoma
brucei) 		PF03199
(GSH_synthase)
PF03917
(GSH_synth_ATP) 		4 VAL A 207
VAL A 206
GLY A 204
PRO A 156
 None
 0.95A 3bjwA-2wyoA:
undetectable		 3bjwA-2wyoA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yd0 ENDOPLASMIC
RETICULUM
AMINOPEPTIDASE 1

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		4 VAL A 147
VAL A 148
PRO A 192
ARG A 108
 None
 0.98A 3bjwA-2yd0A:
2.0		 3bjwA-2yd0A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zvf ALANYL-TRNA
SYNTHETASE

(Archaeoglobus
fulgidus) 		PF02272
(DHHA1) 		4 VAL A 810
VAL A 811
GLY A 836
LYS A 832
 None
 0.97A 3bjwA-2zvfA:
undetectable		 3bjwA-2zvfA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY

(Thermus
thermophilus) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		4 VAL A  72
GLY A  26
PRO A  47
LYS A   1
 None
 0.92A 3bjwA-3b02A:
undetectable		 3bjwA-3b02A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR

(Klebsiella
pneumoniae) 		PF13407
(Peripla_BP_4) 		4 VAL A  50
VAL A  51
GLY A  54
LYS A  55
 None
 0.27A 3bjwA-3d02A:
undetectable		 3bjwA-3d02A:
18.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L

(Vipera
ammodytes) 		PF00068
(Phospholip_A2_1) 		5 VAL A   2
GLY A   6
LYS A   7
PRO A  17
LYS A  60
 None
 1.23A 3bjwA-3dihA:
22.1		 3bjwA-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L

(Vipera
ammodytes) 		PF00068
(Phospholip_A2_1) 		5 VAL A   2
GLY A   6
PRO A  17
LYS A  60
ARG A  63
 None
 1.00A 3bjwA-3dihA:
22.1		 3bjwA-3dihA:
64.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fdt CHROMOBOX PROTEIN
HOMOLOG 5

(Homo sapiens) 		PF00385
(Chromo) 		4 VAL A  14
VAL A  15
GLY A  17
ARG A  13
 None
 0.94A 3bjwA-3fdtA:
undetectable		 3bjwA-3fdtA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3g8g PHOSPHOLIPASE A2,
AMMODYTOXIN A

(Vipera
ammodytes) 		PF00068
(Phospholip_A2_1) 		4 GLY A   6
PRO A  17
LYS A  60
ARG A  63
 None
 0.87A 3bjwA-3g8gA:
21.3		 3bjwA-3g8gA:
63.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g9h SUPPRESSOR OF YEAST
PROFILIN DELETION

(Saccharomyces
cerevisiae) 		PF10291
(muHD) 		4 VAL A 751
GLY A 811
LYS A 810
ARG A 775
 None
 0.77A 3bjwA-3g9hA:
undetectable		 3bjwA-3g9hA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3go7 RIBOKINASE RBSK

(Mycobacterium
tuberculosis) 		PF00294
(PfkB) 		4 VAL A 224
VAL A 219
GLY A 220
ARG A 217
 None
 0.98A 3bjwA-3go7A:
undetectable		 3bjwA-3go7A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hxw ALANYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF01411
(tRNA-synt_2c) 		4 VAL A  49
GLY A  52
PRO A 230
ARG A  56
 None
 0.92A 3bjwA-3hxwA:
undetectable		 3bjwA-3hxwA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k9c TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY PROTEIN

(Rhodococcus
jostii) 		PF13377
(Peripla_BP_3) 		4 VAL A 152
VAL A 153
GLY A 133
PRO A 197
 None
 0.83A 3bjwA-3k9cA:
undetectable		 3bjwA-3k9cA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k9d ALDEHYDE
DEHYDROGENASE

(Listeria
monocytogenes) 		PF00171
(Aldedh) 		4 VAL A 285
GLY A 288
LYS A 289
PRO A 337
 None
 0.58A 3bjwA-3k9dA:
undetectable		 3bjwA-3k9dA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n94 FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PITUITARY
ADENYLATE CYCLASE 1
RECEPTOR-SHORT

(Escherichia
coli;
Homo sapiens) 		PF02793
(HRM)
PF13416
(SBP_bac_8) 		4 VAL A-238
GLY A -48
PRO A-119
LYS A -43
 None
 0.89A 3bjwA-3n94A:
undetectable		 3bjwA-3n94A:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o3u MALTOSE-BINDING
PERIPLASMIC PROTEIN,
ADVANCED
GLYCOSYLATION END
PRODUCT-SPECIFIC
RECEPTOR

(Escherichia
coli;
Homo sapiens) 		PF08205
(C2-set_2)
PF13416
(SBP_bac_8) 		4 VAL N 110
GLY N 300
PRO N 229
LYS N 305
 None
 0.88A 3bjwA-3o3uN:
undetectable		 3bjwA-3o3uN:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ob4 MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
ARAH 2

(Arachis
duranensis;
Escherichia
coli) 		PF00234
(Tryp_alpha_amyl)
PF13416
(SBP_bac_8) 		4 VAL A 110
GLY A 300
PRO A 229
LYS A 305
 None
 0.81A 3bjwA-3ob4A:
undetectable		 3bjwA-3ob4A:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN

(Aequorea
victoria;
Escherichia
coli) 		PF01353
(GFP)
PF01547
(SBP_bac_1) 		4 VAL A 110
GLY A 300
PRO A 229
LYS A 305
 None
 0.89A 3bjwA-3osrA:
undetectable		 3bjwA-3osrA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oxh RV0577 PROTEIN

(Mycobacterium
tuberculosis) 		PF00903
(Glyoxalase) 		4 VAL A  93
VAL A  94
GLY A  97
PRO A 119
 None
 0.89A 3bjwA-3oxhA:
undetectable		 3bjwA-3oxhA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pc3 CG1753, ISOFORM A

(Drosophila
melanogaster) 		PF00291
(PALP)
PF00571
(CBS) 		4 GLY A 426
LYS A 454
LYS A 394
LYS A 450
 None
 0.95A 3bjwA-3pc3A:
undetectable		 3bjwA-3pc3A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3py7 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,PAXILLIN
LD1,PROTEIN E6
CHIMERA

(Deltapapillomavirus
4;
Escherichia
coli;
Homo sapiens) 		PF00518
(E6)
PF01547
(SBP_bac_1) 		4 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
 0.84A 3bjwA-3py7A:
undetectable		 3bjwA-3py7A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rmr AVIRULENCE PROTEIN

(Hyaloperonospora
parasitica) 		no annotation 4 VAL A  94
VAL A  95
LYS A  99
LYS A  90
 None
 0.69A 3bjwA-3rmrA:
undetectable		 3bjwA-3rmrA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t95 AUTOINDUCER
2-BINDING PROTEIN
LSRB

(Yersinia pestis) 		PF13407
(Peripla_BP_4) 		4 VAL A 267
VAL A 268
GLY A 271
LYS A 272
 None
 0.40A 3bjwA-3t95A:
undetectable		 3bjwA-3t95A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2

(Escherichia
coli;
Homo sapiens) 		PF02758
(PYRIN)
PF13416
(SBP_bac_8) 		4 VAL A 110
GLY A 300
PRO A 229
LYS A 305
 None
 0.86A 3bjwA-3vd8A:
undetectable		 3bjwA-3vd8A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vn5 RIBONUCLEASE HIII

(Aquifex
aeolicus) 		PF01351
(RNase_HII) 		4 GLY A  86
PRO A 139
LYS A 213
ARG A 211
 None
 0.94A 3bjwA-3vn5A:
undetectable		 3bjwA-3vn5A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr0 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pyrococcus
furiosus) 		PF09754
(PAC2) 		4 VAL A 216
GLY A  40
LYS A 219
ARG A 244
 None
 0.68A 3bjwA-3vr0A:
undetectable		 3bjwA-3vr0A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E

(Streptomyces
cinnabarigriseus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 VAL A 288
VAL A 289
GLY A 292
ARG A 286
 None
 0.88A 3bjwA-4a0sA:
undetectable		 3bjwA-4a0sA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a35 MITOCHONDRIAL
ENOLASE SUPERFAMILY
MEMBER 1

(Homo sapiens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		5 VAL A  43
VAL A  44
GLY A  55
LYS A  54
ARG A  16
 None
 1.40A 3bjwA-4a35A:
undetectable		 3bjwA-4a35A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b9x TUDOR
DOMAIN-CONTAINING
PROTEIN 1

(Mus musculus) 		PF00567
(TUDOR) 		4 VAL A 855
VAL A 856
GLY A 864
ARG A 854
 None
 0.96A 3bjwA-4b9xA:
undetectable		 3bjwA-4b9xA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4by6 GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 1
GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 2

(Saccharomyces
cerevisiae) 		PF04054
(Not1)
PF04153
(NOT2_3_5) 		4 VAL A1804
VAL A1805
GLY A1808
PRO B  59
 None
 0.98A 3bjwA-4by6A:
undetectable		 3bjwA-4by6A:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c51 CATALASE-PEROXIDASE

(Mycobacterium
tuberculosis) 		PF00141
(peroxidase) 		4 VAL A 544
VAL A 545
GLY A 547
ARG A 571
 None
 0.60A 3bjwA-4c51A:
undetectable		 3bjwA-4c51A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c51 CATALASE-PEROXIDASE

(Mycobacterium
tuberculosis) 		PF00141
(peroxidase) 		4 VAL A 544
VAL A 545
GLY A 548
ARG A 571
 None
 0.83A 3bjwA-4c51A:
undetectable		 3bjwA-4c51A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4edq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MYOSIN-BINDI
NG PROTEIN C,
CARDIAC-TYPE
CHIMERIC PROTEIN

(Escherichia
coli;
Mus musculus) 		PF07679
(I-set)
PF13416
(SBP_bac_8) 		4 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
 0.88A 3bjwA-4edqA:
undetectable		 3bjwA-4edqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4giz MALTOSE-BINDING
PERIPLASMIC PROTEIN,
UBIQUITIN LIGASE
EA6P: CHIMERIC
PROTEIN

(Escherichia
coli;
Homo sapiens) 		PF01547
(SBP_bac_1) 		4 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
 0.82A 3bjwA-4gizA:
undetectable		 3bjwA-4gizA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4he8 NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 8

(Thermus
thermophilus) 		no annotation 4 VAL H  20
VAL H  21
GLY H  23
LYS H  16
 None
 0.87A 3bjwA-4he8H:
undetectable		 3bjwA-4he8H:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4irl MALTOSE-BINDING
PERIPLASMIC PROTEIN,
NOVEL PROTEIN
SIMILAR TO
VERTEBRATE GUANYLATE
BINDING PROTEIN
FAMILY

(Danio rerio;
Escherichia
coli) 		PF00619
(CARD)
PF13416
(SBP_bac_8) 		4 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
 0.91A 3bjwA-4irlA:
undetectable		 3bjwA-4irlA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jrm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Vibrio cholerae) 		no annotation 4 VAL D 313
GLY D 311
PRO D 273
LYS D 225
 None
 0.82A 3bjwA-4jrmD:
undetectable		 3bjwA-4jrmD:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4knh NUP192P

(Chaetomium
thermophilum) 		PF11894
(Nup192) 		4 VAL A 931
VAL A 932
GLY A 935
LYS A 936
 None
 0.47A 3bjwA-4knhA:
undetectable		 3bjwA-4knhA:
7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ktd GE136 HEAVY CHAIN
FAB
GE136 LIGHT CHAIN
FAB

(Macaca mulatta) 		PF07654
(C1-set)
PF07686
(V-set) 		5 VAL H  93
VAL H 102
GLY H 104
PRO L  43
ARG H  94
 None
 1.22A 3bjwA-4ktdH:
undetectable		 3bjwA-4ktdH:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nh0 CELL
DIVISIONFTSK/SPOIIIE

(Thermomonospora
curvata) 		PF01580
(FtsK_SpoIIIE) 		4 VAL A 801
VAL A 802
GLY A 803
PRO A 770
 None
 0.98A 3bjwA-4nh0A:
undetectable		 3bjwA-4nh0A:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ou4 ALPHA/BETA HYDROLASE
FOLD-3 DOMAIN
PROTEIN

(Pseudomonas sp.
ECU1011) 		PF07859
(Abhydrolase_3) 		4 VAL A 105
VAL A 106
GLY A 109
ARG A 102
 None
 0.96A 3bjwA-4ou4A:
undetectable		 3bjwA-4ou4A:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qvh MALTOSE-BINDING
PERIPLASMIC PROTEIN,
4'-PHOSPHOPANTETHEIN
YL TRANSFERASE
CHIMERA

(Escherichia
coli;
Mycobacterium
tuberculosis) 		PF01648
(ACPS)
PF13416
(SBP_bac_8) 		4 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
 0.88A 3bjwA-4qvhA:
undetectable		 3bjwA-4qvhA:
13.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1

(Bothrops
jararacussu) 		PF00068
(Phospholip_A2_1) 		4 GLY A   6
LYS A   7
PRO A  17
ARG A  63
 None
 0.71A 3bjwA-4wtbA:
20.6		 3bjwA-4wtbA:
56.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x28 ACYL-COA
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		no annotation 4 VAL D  91
VAL D  92
GLY D  96
PRO D  58
 None
 0.94A 3bjwA-4x28D:
undetectable		 3bjwA-4x28D:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xa2 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MBP-PILA: C

(Acinetobacter
baumannii;
Escherichia
coli) 		PF00114
(Pilin)
PF13416
(SBP_bac_8) 		4 VAL A 110
GLY A 300
PRO A 229
LYS A 305
 None
 0.83A 3bjwA-4xa2A:
undetectable		 3bjwA-4xa2A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xaj MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NUCLEAR
RECEPTOR SUBFAMILY 2
GROUP E MEMBER 1

(Escherichia
coli;
Homo sapiens) 		PF00104
(Hormone_recep)
PF13416
(SBP_bac_8) 		4 VAL A 112
GLY A 302
PRO A 231
LYS A 307
 None
 0.84A 3bjwA-4xajA:
undetectable		 3bjwA-4xajA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zwj CHIMERA PROTEIN OF
HUMAN RHODOPSIN,
MOUSE S-ARRESTIN,
AND T4 ENDOLYSIN

(Escherichia
virus T4;
Homo sapiens;
Mus musculus) 		PF00001
(7tm_1)
PF00339
(Arrestin_N)
PF00959
(Phage_lysozyme)
PF02752
(Arrestin_C)
PF10413
(Rhodopsin_N) 		4 VAL A2249
GLY A2323
PRO A2128
LYS A 141
 None
 0.96A 3bjwA-4zwjA:
1.8		 3bjwA-4zwjA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cfv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MALTOSE-BIND
ING PERIPLASMIC
PROTEIN,PILA FUSION
PROTEIN

(Acinetobacter
nosocomialis;
Escherichia
coli) 		PF00114
(Pilin)
PF01547
(SBP_bac_1) 		4 VAL A 110
GLY A 300
PRO A 229
LYS A 305
 None
 0.89A 3bjwA-5cfvA:
undetectable		 3bjwA-5cfvA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e8h GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE 3,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00348
(polyprenyl_synt) 		4 VAL A 202
GLY A 204
LYS A 217
ARG A 219
 None
 0.96A 3bjwA-5e8hA:
1.5		 3bjwA-5e8hA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5flz SPINDLE POLE BODY
COMPONENT SPC97

(Saccharomyces
cerevisiae) 		PF04130
(Spc97_Spc98) 		4 VAL A 110
GLY A 113
LYS A 114
ARG A 107
 None
 0.92A 3bjwA-5flzA:
undetectable		 3bjwA-5flzA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fsg MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HANTAVIRUS
NUCLEOPROTEIN

(Hantaan
orthohantavirus) 		PF00846
(Hanta_nucleocap)
PF13416
(SBP_bac_8) 		4 VAL A-262
GLY A -72
PRO A-143
LYS A -67
 None
 0.92A 3bjwA-5fsgA:
undetectable		 3bjwA-5fsgA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hb4 NUP192,NUCLEOPORIN
NUP192

(Chaetomium
thermophilum) 		PF11894
(Nup192) 		4 VAL B 931
VAL B 932
GLY B 935
LYS B 936
 None
 0.43A 3bjwA-5hb4B:
undetectable		 3bjwA-5hb4B:
6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hz7 COMP

(Neisseria
meningitidis) 		PF13416
(SBP_bac_8)
PF16732
(ComP_DUS) 		4 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
NA  A 507 (-3.5A)
None
None
 0.87A 3bjwA-5hz7A:
undetectable		 3bjwA-5hz7A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN

(Escherichia
coli;
Homo sapiens) 		PF00100
(Zona_pellucida)
PF13416
(SBP_bac_8) 		4 VAL A 477
GLY A 667
PRO A 596
LYS A 672
 None
 0.94A 3bjwA-5hzvA:
undetectable		 3bjwA-5hzvA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzw MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN

(Escherichia
coli;
Homo sapiens) 		PF13416
(SBP_bac_8) 		4 VAL A 165
GLY A 355
PRO A 284
LYS A 360
 None
 0.91A 3bjwA-5hzwA:
undetectable		 3bjwA-5hzwA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idn CYCLIN-DEPENDENT
KINASE 8

(Homo sapiens) 		PF00069
(Pkinase) 		4 VAL A 128
GLY A 126
LYS A 123
PRO A 339
 None
 0.95A 3bjwA-5idnA:
undetectable		 3bjwA-5idnA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens) 		PF11386
(VERL)
PF13416
(SBP_bac_8) 		4 VAL A3777
GLY A3967
PRO A3896
LYS A3972
 None
 0.95A 3bjwA-5ii5A:
undetectable		 3bjwA-5ii5A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iic MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens) 		PF11386
(VERL)
PF13416
(SBP_bac_8) 		4 VAL A4079
GLY A4269
PRO A4198
LYS A4274
 None
 0.70A 3bjwA-5iicA:
undetectable		 3bjwA-5iicA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jon MALTOSE-BINDING
PERIPLASMIC
PROTEIN,POTASSIUM/SO
DIUM
HYPERPOLARIZATION-AC
TIVATED CYCLIC
NUCLEOTIDE-GATED
CHANNEL 2

(Escherichia
coli;
Mus musculus) 		PF00027
(cNMP_binding)
PF13416
(SBP_bac_8) 		4 VAL A-259
GLY A -69
PRO A-140
LYS A -64
 None
 0.89A 3bjwA-5jonA:
undetectable		 3bjwA-5jonA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kkx TBPB

(Neisseria
meningitidis) 		PF01298
(TbpB_B_D)
PF17483
(TbpB_C) 		4 VAL A 480
LYS A 608
ARG A 482
LYS A 522
 None
 0.86A 3bjwA-5kkxA:
undetectable		 3bjwA-5kkxA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lb3 ATP-DEPENDENT DNA
HELICASE Q5

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16124
(RecQ_Zn_bind) 		4 VAL B  41
VAL B  42
GLY B  44
PRO B 187
 None
 0.86A 3bjwA-5lb3B:
undetectable		 3bjwA-5lb3B:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lb8 ATP-DEPENDENT DNA
HELICASE Q5

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16124
(RecQ_Zn_bind) 		4 VAL A  41
VAL A  42
GLY A  44
PRO A 187
 None
 0.94A 3bjwA-5lb8A:
undetectable		 3bjwA-5lb8A:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m6q UNCHARACTERIZED
PROTEIN

(Kutzneria
albida) 		PF09017
(Transglut_prok) 		4 VAL A 217
GLY A  69
PRO A 151
LYS A 130
 None
 0.89A 3bjwA-5m6qA:
undetectable		 3bjwA-5m6qA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nbg GENERAL SECRETION
PATHWAY PROTEIN F

(Dickeya
dadantii) 		no annotation 4 VAL A 114
VAL A 115
GLY A 117
ARG A 111
 None
 0.98A 3bjwA-5nbgA:
undetectable		 3bjwA-5nbgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ZONA
PELLUCIDA
SPERM-BINDING
PROTEIN 3

(Escherichia
coli;
Mus musculus) 		PF00100
(Zona_pellucida)
PF13416
(SBP_bac_8) 		4 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
 0.89A 3bjwA-5osqA:
undetectable		 3bjwA-5osqA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5txf PHOSPHATIDYLCHOLINE-
STEROL
ACYLTRANSFERASE

(Homo sapiens) 		no annotation 4 VAL A 134
VAL A 129
GLY A 132
ARG A 135
 None
 0.95A 3bjwA-5txfA:
undetectable		 3bjwA-5txfA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u1o GLUTATHIONE
REDUCTASE

(Vibrio
parahaemolyticus) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 VAL A 184
GLY A 188
PRO A 227
LYS A  55
 None
 0.90A 3bjwA-5u1oA:
undetectable		 3bjwA-5u1oA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v36 GLUTATHIONE
REDUCTASE

(Streptococcus
mutans) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 VAL A 180
GLY A 184
PRO A 223
LYS A  51
 None
 0.91A 3bjwA-5v36A:
undetectable		 3bjwA-5v36A:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v6y MALTOSE-BINDING
PERIPLASMIC
PROTEIN,RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 1,CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR

(Escherichia
coli;
Homo sapiens) 		no annotation 4 VAL A 112
GLY A 302
PRO A 231
LYS A 307
 None
 0.94A 3bjwA-5v6yA:
undetectable		 3bjwA-5v6yA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vip MDCE

(Pseudomonas
aeruginosa) 		PF06833
(MdcE) 		5 VAL A  47
VAL A  48
GLY A  61
PRO A  98
ARG A  31
 None
 1.15A 3bjwA-5vipA:
undetectable		 3bjwA-5vipA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x7s GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE

(Paenibacillus
sp. 598K) 		PF01055
(Glyco_hydro_31)
PF16338
(DUF4968)
PF16990
(CBM_35)
PF17137
(DUF5110) 		4 VAL A 564
GLY A 531
PRO A 544
ARG A 563
 None
None
EDO  A1804 (-4.8A)
None
 0.93A 3bjwA-5x7sA:
undetectable		 3bjwA-5x7sA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxu RIBOSOMAL PROTEIN
US4

(Toxoplasma
gondii) 		PF00163
(Ribosomal_S4)
PF01479
(S4) 		4 VAL J 172
GLY J 170
PRO J 163
ARG J 175
 A  2 510 ( 4.6A)
U  2 512 ( 3.4A)
U  2 512 ( 4.4A)
A  2 537 ( 3.8A)
 0.85A 3bjwA-5xxuJ:
undetectable		 3bjwA-5xxuJ:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y37 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Streptococcus
agalactiae) 		no annotation 4 VAL A  76
GLY A  68
LYS A  65
PRO A  42
 None
 0.94A 3bjwA-5y37A:
undetectable		 3bjwA-5y37A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z0r EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY
1,VIRAL GENOME
PROTEIN

(Escherichia
coli) 		no annotation 4 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
 0.60A 3bjwA-5z0rA:
undetectable		 3bjwA-5z0rA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6anv ANTI-CRISPR PROTEIN
ACRF1 FUSED WITH
C-TERMINAL MBP TAG

(Escherichia
coli;
Pseudomonas
phage JBD30) 		no annotation 4 VAL A 190
GLY A 380
PRO A 309
LYS A 385
 None
 0.92A 3bjwA-6anvA:
undetectable		 3bjwA-6anvA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ce2 -

(-) 		no annotation 5 GLY A   6
LYS A   7
PRO A  18
LYS A  69
ARG A  72
 PE4  A 201 (-3.3A)
None
PE4  A 201 (-4.6A)
None
None
 1.12A 3bjwA-6ce2A:
20.2		 3bjwA-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ce2 -

(-) 		no annotation 4 VAL A   3
GLY A   6
PRO A  18
ARG A  72
 None
PE4  A 201 (-3.3A)
PE4  A 201 (-4.6A)
None
 0.76A 3bjwA-6ce2A:
20.2		 3bjwA-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dm8 -

(-) 		no annotation 4 VAL A-105
GLY A  85
PRO A  14
LYS A  90
 6AK  A 403 ( 4.9A)
None
None
6AK  A 403 ( 4.1A)
 0.95A 3bjwA-6dm8A:
undetectable		 3bjwA-6dm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eu9 RETINOIC ACID
RECEPTOR

(Platynereis
dumerilii) 		no annotation 4 VAL A 367
VAL A 368
GLY A 371
LYS A 372
 None
 0.54A 3bjwA-6eu9A:
undetectable		 3bjwA-6eu9A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fbt LYTIC MUREIN
TRANSGLYCOSYLASE

(Pseudomonas
aeruginosa) 		no annotation 4 VAL A 240
VAL A 241
GLY A 244
LYS A 274
 None
 0.70A 3bjwA-6fbtA:
1.7		 3bjwA-6fbtA:
17.65