SIMILAR PATTERNS OF AMINO ACIDS FOR 3BJW_G_SVRG506

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
16vp PROTEIN (VP16,
VMW65, ATIF)

(Human
alphaherpesvirus
1) 		PF02232
(Alpha_TIF) 		4 VAL A 112
VAL A 113
GLY A 116
ARG A 208
 None
 0.82A 3bjwA-16vpA:
undetectable		 3bjwA-16vpA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bgp BARLEY GRAIN
PEROXIDASE

(Hordeum vulgare) 		PF00141
(peroxidase) 		4 VAL A 120
VAL A 119
GLY A 122
ARG A  26
 None
 0.85A 3bjwA-1bgpA:
0.1		 3bjwA-1bgpA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bgp BARLEY GRAIN
PEROXIDASE

(Hordeum vulgare) 		PF00141
(peroxidase) 		4 VAL A 279
GLY A 282
LYS A 283
PRO A 129
 None
 0.83A 3bjwA-1bgpA:
0.1		 3bjwA-1bgpA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bsz PROTEIN (PEPTIDE
DEFORMYLASE)

(Escherichia
coli) 		PF01327
(Pep_deformylase) 		4 VAL A  16
VAL A 138
GLY A 139
ARG A  56
 None
 0.95A 3bjwA-1bszA:
undetectable		 3bjwA-1bszA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c4o DNA NUCLEOTIDE
EXCISION REPAIR
ENZYME UVRB

(Thermus
thermophilus) 		PF00271
(Helicase_C)
PF04851
(ResIII)
PF12344
(UvrB) 		4 VAL A  44
GLY A  41
PRO A 409
LYS A  48
 None
SO4  A9001 (-3.5A)
None
None
 0.98A 3bjwA-1c4oA:
undetectable		 3bjwA-1c4oA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dd5 RIBOSOME RECYCLING
FACTOR

(Thermotoga
maritima) 		PF01765
(RRF) 		4 VAL A 121
GLY A 124
LYS A 125
LYS A 116
 None
 0.97A 3bjwA-1dd5A:
2.1		 3bjwA-1dd5A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f81 CREB-BINDING PROTEIN

(Mus musculus) 		PF02135
(zf-TAZ) 		4 VAL A  39
VAL A  40
LYS A  44
LYS A  35
 None
 0.93A 3bjwA-1f81A:
undetectable		 3bjwA-1f81A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gcw PROTEIN (HEMOGLOBIN)

(Mustelus
griseus) 		PF00042
(Globin) 		4 VAL A  57
GLY A  60
LYS A  61
PRO A  21
 None
 0.92A 3bjwA-1gcwA:
0.2		 3bjwA-1gcwA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k7y METHIONINE SYNTHASE

(Escherichia
coli) 		PF02310
(B12-binding)
PF02607
(B12-binding_2)
PF02965
(Met_synt_B12) 		4 VAL A 668
GLY A 700
LYS A 669
LYS A 726
 None
 0.94A 3bjwA-1k7yA:
0.0		 3bjwA-1k7yA:
11.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mc2 ACUTOHAEMONLYSIN

(Deinagkistrodon
acutus) 		PF00068
(Phospholip_A2_1) 		4 GLY A1006
LYS A1007
PRO A1017
ARG A1072
 IPA  A1136 (-3.6A)
None
IPA  A1136 (-4.4A)
None
 0.96A 3bjwA-1mc2A:
20.1		 3bjwA-1mc2A:
56.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nu2 DISABLED HOMOLOG 1

(Mus musculus) 		PF00640
(PID) 		4 VAL A  71
VAL A  72
GLY A  74
LYS A  67
 None
 0.86A 3bjwA-1nu2A:
undetectable		 3bjwA-1nu2A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rpu 19 KDA PROTEIN

(Carnation
Italian
ringspot virus) 		PF03220
(Tombus_P19) 		5 VAL A  68
VAL A  69
LYS A  71
PRO A  29
ARG A  11
 None
C  C  10 ( 4.8A)
A  C  11 ( 2.9A)
None
C  C  10 ( 2.7A)
 1.41A 3bjwA-1rpuA:
undetectable		 3bjwA-1rpuA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vp4 AMINOTRANSFERASE,
PUTATIVE

(Thermotoga
maritima) 		PF00155
(Aminotran_1_2) 		4 VAL A 403
GLY A 407
LYS A 408
ARG A 400
 None
None
None
FMT  A 620 ( 3.5A)
 0.83A 3bjwA-1vp4A:
undetectable		 3bjwA-1vp4A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y3n ALGQ1

(Sphingomonas
sp. A1) 		PF01547
(SBP_bac_1) 		4 VAL A  35
GLY A 341
LYS A 340
ARG A  37
 None
 0.96A 3bjwA-1y3nA:
undetectable		 3bjwA-1y3nA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y4c MALTOSE BINDING
PROTEIN FUSED WITH
DESIGNED HELICAL
PROTEIN

(Escherichia
coli) 		PF13416
(SBP_bac_8) 		4 VAL A 110
GLY A 300
PRO A 229
LYS A 305
 None
 0.93A 3bjwA-1y4cA:
undetectable		 3bjwA-1y4cA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yt5 INORGANIC
POLYPHOSPHATE/ATP-NA
D KINASE

(Thermotoga
maritima) 		PF01513
(NAD_kinase) 		4 VAL A 203
VAL A 202
LYS A 200
ARG A 223
 None
 0.89A 3bjwA-1yt5A:
undetectable		 3bjwA-1yt5A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bdz MEXICAIN

(Jacaratia
mexicana) 		PF00112
(Peptidase_C1) 		4 VAL A 105
VAL A  80
GLY A  79
LYS A 100
 None
 0.96A 3bjwA-2bdzA:
undetectable		 3bjwA-2bdzA:
26.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l4v CYSTATIN

(Ananas comosus) 		PF16845
(SQAPI) 		4 VAL A  90
VAL A  91
GLY A  93
LYS A 114
 None
 0.90A 3bjwA-2l4vA:
undetectable		 3bjwA-2l4vA:
17.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		5 VAL A   2
VAL A   3
GLY A   6
PRO A  18
ARG A  72
 None
 1.36A 3bjwA-2qheA:
22.8		 3bjwA-2qheA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vdc GLUTAMATE SYNTHASE
[NADPH] LARGE CHAIN

(Azospirillum
brasilense) 		PF00310
(GATase_2)
PF01493
(GXGXG)
PF01645
(Glu_synthase)
PF04898
(Glu_syn_central) 		4 VAL A  17
VAL A  18
GLY A  21
ARG A  15
 None
 0.89A 3bjwA-2vdcA:
undetectable		 3bjwA-2vdcA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wyo GLUTATHIONE
SYNTHETASE

(Trypanosoma
brucei) 		PF03199
(GSH_synthase)
PF03917
(GSH_synth_ATP) 		4 VAL A 207
VAL A 206
GLY A 204
PRO A 156
 None
 0.95A 3bjwA-2wyoA:
undetectable		 3bjwA-2wyoA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yd0 ENDOPLASMIC
RETICULUM
AMINOPEPTIDASE 1

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		4 VAL A 147
VAL A 148
PRO A 192
ARG A 108
 None
 0.98A 3bjwA-2yd0A:
2.0		 3bjwA-2yd0A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zvf ALANYL-TRNA
SYNTHETASE

(Archaeoglobus
fulgidus) 		PF02272
(DHHA1) 		4 VAL A 810
VAL A 811
GLY A 836
LYS A 832
 None
 0.97A 3bjwA-2zvfA:
undetectable		 3bjwA-2zvfA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY

(Thermus
thermophilus) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		4 VAL A  72
GLY A  26
PRO A  47
LYS A   1
 None
 0.92A 3bjwA-3b02A:
undetectable		 3bjwA-3b02A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR

(Klebsiella
pneumoniae) 		PF13407
(Peripla_BP_4) 		4 VAL A  50
VAL A  51
GLY A  54
LYS A  55
 None
 0.27A 3bjwA-3d02A:
undetectable		 3bjwA-3d02A:
18.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L

(Vipera
ammodytes) 		PF00068
(Phospholip_A2_1) 		5 VAL A   2
GLY A   6
LYS A   7
PRO A  17
LYS A  60
 None
 1.23A 3bjwA-3dihA:
22.1		 3bjwA-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L

(Vipera
ammodytes) 		PF00068
(Phospholip_A2_1) 		5 VAL A   2
GLY A   6
PRO A  17
LYS A  60
ARG A  63
 None
 1.00A 3bjwA-3dihA:
22.1		 3bjwA-3dihA:
64.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fdt CHROMOBOX PROTEIN
HOMOLOG 5

(Homo sapiens) 		PF00385
(Chromo) 		4 VAL A  14
VAL A  15
GLY A  17
ARG A  13
 None
 0.94A 3bjwA-3fdtA:
undetectable		 3bjwA-3fdtA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3g8g PHOSPHOLIPASE A2,
AMMODYTOXIN A

(Vipera
ammodytes) 		PF00068
(Phospholip_A2_1) 		4 GLY A   6
PRO A  17
LYS A  60
ARG A  63
 None
 0.87A 3bjwA-3g8gA:
21.3		 3bjwA-3g8gA:
63.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g9h SUPPRESSOR OF YEAST
PROFILIN DELETION

(Saccharomyces
cerevisiae) 		PF10291
(muHD) 		4 VAL A 751
GLY A 811
LYS A 810
ARG A 775
 None
 0.77A 3bjwA-3g9hA:
undetectable		 3bjwA-3g9hA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3go7 RIBOKINASE RBSK

(Mycobacterium
tuberculosis) 		PF00294
(PfkB) 		4 VAL A 224
VAL A 219
GLY A 220
ARG A 217
 None
 0.98A 3bjwA-3go7A:
undetectable		 3bjwA-3go7A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hxw ALANYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF01411
(tRNA-synt_2c) 		4 VAL A  49
GLY A  52
PRO A 230
ARG A  56
 None
 0.92A 3bjwA-3hxwA:
undetectable		 3bjwA-3hxwA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k9c TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY PROTEIN

(Rhodococcus
jostii) 		PF13377
(Peripla_BP_3) 		4 VAL A 152
VAL A 153
GLY A 133
PRO A 197
 None
 0.83A 3bjwA-3k9cA:
undetectable		 3bjwA-3k9cA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k9d ALDEHYDE
DEHYDROGENASE

(Listeria
monocytogenes) 		PF00171
(Aldedh) 		4 VAL A 285
GLY A 288
LYS A 289
PRO A 337
 None
 0.58A 3bjwA-3k9dA:
undetectable		 3bjwA-3k9dA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n94 FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PITUITARY
ADENYLATE CYCLASE 1
RECEPTOR-SHORT

(Escherichia
coli;
Homo sapiens) 		PF02793
(HRM)
PF13416
(SBP_bac_8) 		4 VAL A-238
GLY A -48
PRO A-119
LYS A -43
 None
 0.89A 3bjwA-3n94A:
undetectable		 3bjwA-3n94A:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o3u MALTOSE-BINDING
PERIPLASMIC PROTEIN,
ADVANCED
GLYCOSYLATION END
PRODUCT-SPECIFIC
RECEPTOR

(Escherichia
coli;
Homo sapiens) 		PF08205
(C2-set_2)
PF13416
(SBP_bac_8) 		4 VAL N 110
GLY N 300
PRO N 229
LYS N 305
 None
 0.88A 3bjwA-3o3uN:
undetectable		 3bjwA-3o3uN:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ob4 MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
ARAH 2

(Arachis
duranensis;
Escherichia
coli) 		PF00234
(Tryp_alpha_amyl)
PF13416
(SBP_bac_8) 		4 VAL A 110
GLY A 300
PRO A 229
LYS A 305
 None
 0.81A 3bjwA-3ob4A:
undetectable		 3bjwA-3ob4A:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN

(Aequorea
victoria;
Escherichia
coli) 		PF01353
(GFP)
PF01547
(SBP_bac_1) 		4 VAL A 110
GLY A 300
PRO A 229
LYS A 305
 None
 0.89A 3bjwA-3osrA:
undetectable		 3bjwA-3osrA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oxh RV0577 PROTEIN

(Mycobacterium
tuberculosis) 		PF00903
(Glyoxalase) 		4 VAL A  93
VAL A  94
GLY A  97
PRO A 119
 None
 0.89A 3bjwA-3oxhA:
undetectable		 3bjwA-3oxhA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pc3 CG1753, ISOFORM A

(Drosophila
melanogaster) 		PF00291
(PALP)
PF00571
(CBS) 		4 GLY A 426
LYS A 454
LYS A 394
LYS A 450
 None
 0.95A 3bjwA-3pc3A:
undetectable		 3bjwA-3pc3A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3py7 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,PAXILLIN
LD1,PROTEIN E6
CHIMERA

(Deltapapillomavirus
4;
Escherichia
coli;
Homo sapiens) 		PF00518
(E6)
PF01547
(SBP_bac_1) 		4 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
 0.84A 3bjwA-3py7A:
undetectable		 3bjwA-3py7A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rmr AVIRULENCE PROTEIN

(Hyaloperonospora
parasitica) 		no annotation 4 VAL A  94
VAL A  95
LYS A  99
LYS A  90
 None
 0.69A 3bjwA-3rmrA:
undetectable		 3bjwA-3rmrA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t95 AUTOINDUCER
2-BINDING PROTEIN
LSRB

(Yersinia pestis) 		PF13407
(Peripla_BP_4) 		4 VAL A 267
VAL A 268
GLY A 271
LYS A 272
 None
 0.40A 3bjwA-3t95A:
undetectable		 3bjwA-3t95A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2

(Escherichia
coli;
Homo sapiens) 		PF02758
(PYRIN)
PF13416
(SBP_bac_8) 		4 VAL A 110
GLY A 300
PRO A 229
LYS A 305
 None
 0.86A 3bjwA-3vd8A:
undetectable		 3bjwA-3vd8A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vn5 RIBONUCLEASE HIII

(Aquifex
aeolicus) 		PF01351
(RNase_HII) 		4 GLY A  86
PRO A 139
LYS A 213
ARG A 211
 None
 0.94A 3bjwA-3vn5A:
undetectable		 3bjwA-3vn5A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr0 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pyrococcus
furiosus) 		PF09754
(PAC2) 		4 VAL A 216
GLY A  40
LYS A 219
ARG A 244
 None
 0.68A 3bjwA-3vr0A:
undetectable		 3bjwA-3vr0A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E

(Streptomyces
cinnabarigriseus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 VAL A 288
VAL A 289
GLY A 292
ARG A 286
 None
 0.88A 3bjwA-4a0sA:
undetectable		 3bjwA-4a0sA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a35 MITOCHONDRIAL
ENOLASE SUPERFAMILY
MEMBER 1

(Homo sapiens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		5 VAL A  43
VAL A  44
GLY A  55
LYS A  54
ARG A  16
 None
 1.40A 3bjwA-4a35A:
undetectable		 3bjwA-4a35A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b9x TUDOR
DOMAIN-CONTAINING
PROTEIN 1

(Mus musculus) 		PF00567
(TUDOR) 		4 VAL A 855
VAL A 856
GLY A 864
ARG A 854
 None
 0.96A 3bjwA-4b9xA:
undetectable		 3bjwA-4b9xA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4by6 GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 1
GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 2

(Saccharomyces
cerevisiae) 		PF04054
(Not1)
PF04153
(NOT2_3_5) 		4 VAL A1804
VAL A1805
GLY A1808
PRO B  59
 None
 0.98A 3bjwA-4by6A:
undetectable		 3bjwA-4by6A:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c51 CATALASE-PEROXIDASE

(Mycobacterium
tuberculosis) 		PF00141
(peroxidase) 		4 VAL A 544
VAL A 545
GLY A 547
ARG A 571
 None
 0.60A 3bjwA-4c51A:
undetectable		 3bjwA-4c51A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c51 CATALASE-PEROXIDASE

(Mycobacterium
tuberculosis) 		PF00141
(peroxidase) 		4 VAL A 544
VAL A 545
GLY A 548
ARG A 571
 None
 0.83A 3bjwA-4c51A:
undetectable		 3bjwA-4c51A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4edq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MYOSIN-BINDI
NG PROTEIN C,
CARDIAC-TYPE
CHIMERIC PROTEIN

(Escherichia
coli;
Mus musculus) 		PF07679
(I-set)
PF13416
(SBP_bac_8) 		4 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
 0.88A 3bjwA-4edqA:
undetectable		 3bjwA-4edqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4giz MALTOSE-BINDING
PERIPLASMIC PROTEIN,
UBIQUITIN LIGASE
EA6P: CHIMERIC
PROTEIN

(Escherichia
coli;
Homo sapiens) 		PF01547
(SBP_bac_1) 		4 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
 0.82A 3bjwA-4gizA:
undetectable		 3bjwA-4gizA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4he8 NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 8

(Thermus
thermophilus) 		no annotation 4 VAL H  20
VAL H  21
GLY H  23
LYS H  16
 None
 0.87A 3bjwA-4he8H:
undetectable		 3bjwA-4he8H:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4irl MALTOSE-BINDING
PERIPLASMIC PROTEIN,
NOVEL PROTEIN
SIMILAR TO
VERTEBRATE GUANYLATE
BINDING PROTEIN
FAMILY

(Danio rerio;
Escherichia
coli) 		PF00619
(CARD)
PF13416
(SBP_bac_8) 		4 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
 0.91A 3bjwA-4irlA:
undetectable		 3bjwA-4irlA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jrm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Vibrio cholerae) 		no annotation 4 VAL D 313
GLY D 311
PRO D 273
LYS D 225
 None
 0.82A 3bjwA-4jrmD:
undetectable		 3bjwA-4jrmD:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4knh NUP192P

(Chaetomium
thermophilum) 		PF11894
(Nup192) 		4 VAL A 931
VAL A 932
GLY A 935
LYS A 936
 None
 0.47A 3bjwA-4knhA:
undetectable		 3bjwA-4knhA:
7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ktd GE136 HEAVY CHAIN
FAB
GE136 LIGHT CHAIN
FAB

(Macaca mulatta) 		PF07654
(C1-set)
PF07686
(V-set) 		5 VAL H  93
VAL H 102
GLY H 104
PRO L  43
ARG H  94
 None
 1.22A 3bjwA-4ktdH:
undetectable		 3bjwA-4ktdH:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nh0 CELL
DIVISIONFTSK/SPOIIIE

(Thermomonospora
curvata) 		PF01580
(FtsK_SpoIIIE) 		4 VAL A 801
VAL A 802
GLY A 803
PRO A 770
 None
 0.98A 3bjwA-4nh0A:
undetectable		 3bjwA-4nh0A:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ou4 ALPHA/BETA HYDROLASE
FOLD-3 DOMAIN
PROTEIN

(Pseudomonas sp.
ECU1011) 		PF07859
(Abhydrolase_3) 		4 VAL A 105
VAL A 106
GLY A 109
ARG A 102
 None
 0.96A 3bjwA-4ou4A:
undetectable		 3bjwA-4ou4A:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qvh MALTOSE-BINDING
PERIPLASMIC PROTEIN,
4'-PHOSPHOPANTETHEIN
YL TRANSFERASE
CHIMERA

(Escherichia
coli;
Mycobacterium
tuberculosis) 		PF01648
(ACPS)
PF13416
(SBP_bac_8) 		4 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
 0.88A 3bjwA-4qvhA:
undetectable		 3bjwA-4qvhA:
13.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1

(Bothrops
jararacussu) 		PF00068
(Phospholip_A2_1) 		4 GLY A   6
LYS A   7
PRO A  17
ARG A  63
 None
 0.71A 3bjwA-4wtbA:
20.6		 3bjwA-4wtbA:
56.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x28 ACYL-COA
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		no annotation 4 VAL D  91
VAL D  92
GLY D  96
PRO D  58
 None
 0.94A 3bjwA-4x28D:
undetectable		 3bjwA-4x28D:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xa2 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MBP-PILA: C

(Acinetobacter
baumannii;
Escherichia
coli) 		PF00114
(Pilin)
PF13416
(SBP_bac_8) 		4 VAL A 110
GLY A 300
PRO A 229
LYS A 305
 None
 0.83A 3bjwA-4xa2A:
undetectable		 3bjwA-4xa2A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xaj MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NUCLEAR
RECEPTOR SUBFAMILY 2
GROUP E MEMBER 1

(Escherichia
coli;
Homo sapiens) 		PF00104
(Hormone_recep)
PF13416
(SBP_bac_8) 		4 VAL A 112
GLY A 302
PRO A 231
LYS A 307
 None
 0.84A 3bjwA-4xajA:
undetectable		 3bjwA-4xajA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zwj CHIMERA PROTEIN OF
HUMAN RHODOPSIN,
MOUSE S-ARRESTIN,
AND T4 ENDOLYSIN

(Escherichia
virus T4;
Homo sapiens;
Mus musculus) 		PF00001
(7tm_1)
PF00339
(Arrestin_N)
PF00959
(Phage_lysozyme)
PF02752
(Arrestin_C)
PF10413
(Rhodopsin_N) 		4 VAL A2249
GLY A2323
PRO A2128
LYS A 141
 None
 0.96A 3bjwA-4zwjA:
1.8		 3bjwA-4zwjA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cfv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MALTOSE-BIND
ING PERIPLASMIC
PROTEIN,PILA FUSION
PROTEIN

(Acinetobacter
nosocomialis;
Escherichia
coli) 		PF00114
(Pilin)
PF01547
(SBP_bac_1) 		4 VAL A 110
GLY A 300
PRO A 229
LYS A 305
 None
 0.89A 3bjwA-5cfvA:
undetectable		 3bjwA-5cfvA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e8h GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE 3,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00348
(polyprenyl_synt) 		4 VAL A 202
GLY A 204
LYS A 217
ARG A 219
 None
 0.96A 3bjwA-5e8hA:
1.5		 3bjwA-5e8hA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5flz SPINDLE POLE BODY
COMPONENT SPC97

(Saccharomyces
cerevisiae) 		PF04130
(Spc97_Spc98) 		4 VAL A 110
GLY A 113
LYS A 114
ARG A 107
 None
 0.92A 3bjwA-5flzA:
undetectable		 3bjwA-5flzA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fsg MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HANTAVIRUS
NUCLEOPROTEIN

(Hantaan
orthohantavirus) 		PF00846
(Hanta_nucleocap)
PF13416
(SBP_bac_8) 		4 VAL A-262
GLY A -72
PRO A-143
LYS A -67
 None
 0.92A 3bjwA-5fsgA:
undetectable		 3bjwA-5fsgA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hb4 NUP192,NUCLEOPORIN
NUP192

(Chaetomium
thermophilum) 		PF11894
(Nup192) 		4 VAL B 931
VAL B 932
GLY B 935
LYS B 936
 None
 0.43A 3bjwA-5hb4B:
undetectable		 3bjwA-5hb4B:
6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hz7 COMP

(Neisseria
meningitidis) 		PF13416
(SBP_bac_8)
PF16732
(ComP_DUS) 		4 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
NA  A 507 (-3.5A)
None
None
 0.87A 3bjwA-5hz7A:
undetectable		 3bjwA-5hz7A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN

(Escherichia
coli;
Homo sapiens) 		PF00100
(Zona_pellucida)
PF13416
(SBP_bac_8) 		4 VAL A 477
GLY A 667
PRO A 596
LYS A 672
 None
 0.94A 3bjwA-5hzvA:
undetectable		 3bjwA-5hzvA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzw MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN

(Escherichia
coli;
Homo sapiens) 		PF13416
(SBP_bac_8) 		4 VAL A 165
GLY A 355
PRO A 284
LYS A 360
 None
 0.91A 3bjwA-5hzwA:
undetectable		 3bjwA-5hzwA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idn CYCLIN-DEPENDENT
KINASE 8

(Homo sapiens) 		PF00069
(Pkinase) 		4 VAL A 128
GLY A 126
LYS A 123
PRO A 339
 None
 0.95A 3bjwA-5idnA:
undetectable		 3bjwA-5idnA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens) 		PF11386
(VERL)
PF13416
(SBP_bac_8) 		4 VAL A3777
GLY A3967
PRO A3896
LYS A3972
 None
 0.95A 3bjwA-5ii5A:
undetectable		 3bjwA-5ii5A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iic MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens) 		PF11386
(VERL)
PF13416
(SBP_bac_8) 		4 VAL A4079
GLY A4269
PRO A4198
LYS A4274
 None
 0.70A 3bjwA-5iicA:
undetectable		 3bjwA-5iicA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jon MALTOSE-BINDING
PERIPLASMIC
PROTEIN,POTASSIUM/SO
DIUM
HYPERPOLARIZATION-AC
TIVATED CYCLIC
NUCLEOTIDE-GATED
CHANNEL 2

(Escherichia
coli;
Mus musculus) 		PF00027
(cNMP_binding)
PF13416
(SBP_bac_8) 		4 VAL A-259
GLY A -69
PRO A-140
LYS A -64
 None
 0.89A 3bjwA-5jonA:
undetectable		 3bjwA-5jonA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kkx TBPB

(Neisseria
meningitidis) 		PF01298
(TbpB_B_D)
PF17483
(TbpB_C) 		4 VAL A 480
LYS A 608
ARG A 482
LYS A 522
 None
 0.86A 3bjwA-5kkxA:
undetectable		 3bjwA-5kkxA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lb3 ATP-DEPENDENT DNA
HELICASE Q5

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16124
(RecQ_Zn_bind) 		4 VAL B  41
VAL B  42
GLY B  44
PRO B 187
 None
 0.86A 3bjwA-5lb3B:
undetectable		 3bjwA-5lb3B:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lb8 ATP-DEPENDENT DNA
HELICASE Q5

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16124
(RecQ_Zn_bind) 		4 VAL A  41
VAL A  42
GLY A  44
PRO A 187
 None
 0.94A 3bjwA-5lb8A:
undetectable		 3bjwA-5lb8A:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m6q UNCHARACTERIZED
PROTEIN

(Kutzneria
albida) 		PF09017
(Transglut_prok) 		4 VAL A 217
GLY A  69
PRO A 151
LYS A 130
 None
 0.89A 3bjwA-5m6qA:
undetectable		 3bjwA-5m6qA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nbg GENERAL SECRETION
PATHWAY PROTEIN F

(Dickeya
dadantii) 		no annotation 4 VAL A 114
VAL A 115
GLY A 117
ARG A 111
 None
 0.98A 3bjwA-5nbgA:
undetectable		 3bjwA-5nbgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ZONA
PELLUCIDA
SPERM-BINDING
PROTEIN 3

(Escherichia
coli;
Mus musculus) 		PF00100
(Zona_pellucida)
PF13416
(SBP_bac_8) 		4 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
 0.89A 3bjwA-5osqA:
undetectable		 3bjwA-5osqA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5txf PHOSPHATIDYLCHOLINE-
STEROL
ACYLTRANSFERASE

(Homo sapiens) 		no annotation 4 VAL A 134
VAL A 129
GLY A 132
ARG A 135
 None
 0.95A 3bjwA-5txfA:
undetectable		 3bjwA-5txfA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u1o GLUTATHIONE
REDUCTASE

(Vibrio
parahaemolyticus) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 VAL A 184
GLY A 188
PRO A 227
LYS A  55
 None
 0.90A 3bjwA-5u1oA:
undetectable		 3bjwA-5u1oA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v36 GLUTATHIONE
REDUCTASE

(Streptococcus
mutans) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 VAL A 180
GLY A 184
PRO A 223
LYS A  51
 None
 0.91A 3bjwA-5v36A:
undetectable		 3bjwA-5v36A:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v6y MALTOSE-BINDING
PERIPLASMIC
PROTEIN,RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 1,CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR

(Escherichia
coli;
Homo sapiens) 		no annotation 4 VAL A 112
GLY A 302
PRO A 231
LYS A 307
 None
 0.94A 3bjwA-5v6yA:
undetectable		 3bjwA-5v6yA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vip MDCE

(Pseudomonas
aeruginosa) 		PF06833
(MdcE) 		5 VAL A  47
VAL A  48
GLY A  61
PRO A  98
ARG A  31
 None
 1.15A 3bjwA-5vipA:
undetectable		 3bjwA-5vipA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x7s GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE

(Paenibacillus
sp. 598K) 		PF01055
(Glyco_hydro_31)
PF16338
(DUF4968)
PF16990
(CBM_35)
PF17137
(DUF5110) 		4 VAL A 564
GLY A 531
PRO A 544
ARG A 563
 None
None
EDO  A1804 (-4.8A)
None
 0.93A 3bjwA-5x7sA:
undetectable		 3bjwA-5x7sA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxu RIBOSOMAL PROTEIN
US4

(Toxoplasma
gondii) 		PF00163
(Ribosomal_S4)
PF01479
(S4) 		4 VAL J 172
GLY J 170
PRO J 163
ARG J 175
 A  2 510 ( 4.6A)
U  2 512 ( 3.4A)
U  2 512 ( 4.4A)
A  2 537 ( 3.8A)
 0.85A 3bjwA-5xxuJ:
undetectable		 3bjwA-5xxuJ:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y37 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Streptococcus
agalactiae) 		no annotation 4 VAL A  76
GLY A  68
LYS A  65
PRO A  42
 None
 0.94A 3bjwA-5y37A:
undetectable		 3bjwA-5y37A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z0r EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY
1,VIRAL GENOME
PROTEIN

(Escherichia
coli) 		no annotation 4 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
 0.60A 3bjwA-5z0rA:
undetectable		 3bjwA-5z0rA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6anv ANTI-CRISPR PROTEIN
ACRF1 FUSED WITH
C-TERMINAL MBP TAG

(Escherichia
coli;
Pseudomonas
phage JBD30) 		no annotation 4 VAL A 190
GLY A 380
PRO A 309
LYS A 385
 None
 0.92A 3bjwA-6anvA:
undetectable		 3bjwA-6anvA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ce2 -

(-) 		no annotation 5 GLY A   6
LYS A   7
PRO A  18
LYS A  69
ARG A  72
 PE4  A 201 (-3.3A)
None
PE4  A 201 (-4.6A)
None
None
 1.12A 3bjwA-6ce2A:
20.2		 3bjwA-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ce2 -

(-) 		no annotation 4 VAL A   3
GLY A   6
PRO A  18
ARG A  72
 None
PE4  A 201 (-3.3A)
PE4  A 201 (-4.6A)
None
 0.76A 3bjwA-6ce2A:
20.2		 3bjwA-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dm8 -

(-) 		no annotation 4 VAL A-105
GLY A  85
PRO A  14
LYS A  90
 6AK  A 403 ( 4.9A)
None
None
6AK  A 403 ( 4.1A)
 0.95A 3bjwA-6dm8A:
undetectable		 3bjwA-6dm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eu9 RETINOIC ACID
RECEPTOR

(Platynereis
dumerilii) 		no annotation 4 VAL A 367
VAL A 368
GLY A 371
LYS A 372
 None
 0.54A 3bjwA-6eu9A:
undetectable		 3bjwA-6eu9A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fbt LYTIC MUREIN
TRANSGLYCOSYLASE

(Pseudomonas
aeruginosa) 		no annotation 4 VAL A 240
VAL A 241
GLY A 244
LYS A 274
 None
 0.70A 3bjwA-6fbtA:
1.7		 3bjwA-6fbtA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)

(Escherichia
coli) 		PF00549
(Ligase_CoA)
PF08442
(ATP-grasp_2) 		4 VAL B 316
VAL B 347
GLN B 380
PHE B 319
 None
 1.39A 3bjwB-1cqiB:
0.0		 3bjwB-1cqiB:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6w SHORT CHAIN
3-HYDROXYACYL-COA
DEHYDROGENASE

(Rattus
norvegicus) 		PF00106
(adh_short) 		4 VAL A 135
VAL A 132
PHE A  82
ARG A 192
 None
 1.39A 3bjwB-1e6wA:
0.0		 3bjwB-1e6wA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE

(Paraburkholderia
xenovorans) 		PF00903
(Glyoxalase) 		4 VAL A 274
VAL A 273
PHE A 187
ARG A 270
 None
None
BP6  A 300 (-4.3A)
None
 1.33A 3bjwB-1lkdA:
0.0		 3bjwB-1lkdA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mox EPIDERMAL GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain) 		4 VAL A  37
VAL A  36
GLN A  81
PHE A  54
 None
 1.36A 3bjwB-1moxA:
undetectable		 3bjwB-1moxA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1odu PUTATIVE
ALPHA-L-FUCOSIDASE

(Thermotoga
maritima) 		PF01120
(Alpha_L_fucos) 		4 VAL A 314
VAL A 315
PHE A 262
ARG A 378
 None
 1.12A 3bjwB-1oduA:
0.0		 3bjwB-1oduA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1px5 2'-5'-OLIGOADENYLATE
SYNTHETASE 1

(Sus scrofa) 		PF01909
(NTP_transf_2)
PF10421
(OAS1_C) 		4 VAL A  78
VAL A  79
PHE A 185
ARG A 102
 None
 1.36A 3bjwB-1px5A:
0.0		 3bjwB-1px5A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1suw PROBABLE INORGANIC
POLYPHOSPHATE/ATP-NA
D KINASE

(Archaeoglobus
fulgidus) 		PF01513
(NAD_kinase) 		4 VAL A   6
VAL A   5
PHE A 231
ARG A  15
 None
 1.39A 3bjwB-1suwA:
0.0		 3bjwB-1suwA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t9k PROBABLE
METHYLTHIORIBOSE-1-P
HOSPHATE ISOMERASE

(Thermotoga
maritima) 		PF01008
(IF-2B) 		4 VAL A 230
VAL A 231
PHE A 184
ARG A  48
 None
None
None
SO4  A 401 (-3.9A)
 1.30A 3bjwB-1t9kA:
0.0		 3bjwB-1t9kA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w97 TYPE II SECRETION
SYSTEM PROTEIN L

(Vibrio cholerae) 		PF05134
(T2SSL) 		4 VAL L  54
VAL L  55
PHE L 231
ARG L 119
 None
 0.94A 3bjwB-1w97L:
0.0		 3bjwB-1w97L:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wvg CDP-GLUCOSE
4,6-DEHYDRATASE

(Salmonella
enterica) 		PF16363
(GDP_Man_Dehyd) 		4 VAL A 130
VAL A 129
PHE A 258
ARG A  13
 None
 1.39A 3bjwB-1wvgA:
undetectable		 3bjwB-1wvgA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yvp 60-KDA SS-A/RO
RIBONUCLEOPROTEIN

(Xenopus laevis) 		PF05731
(TROVE) 		4 VAL A  73
VAL A  74
GLN A  82
PHE A  36
 None
 1.14A 3bjwB-1yvpA:
undetectable		 3bjwB-1yvpA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b39 C3

(Bos taurus) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		4 VAL A 107
VAL A  59
GLN A  67
PHE A 104
 None
 1.37A 3bjwB-2b39A:
undetectable		 3bjwB-2b39A:
5.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bf4 NADPH-CYTOCHROME
P450 REDUCTASE

(Saccharomyces
cerevisiae) 		PF00175
(NAD_binding_1)
PF00258
(Flavodoxin_1)
PF00667
(FAD_binding_1) 		4 VAL A  96
GLN A  68
PHE A 114
ARG A 522
 None
 1.37A 3bjwB-2bf4A:
1.7		 3bjwB-2bf4A:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bw3 TRANSPOSASE

(Musca domestica) 		PF05699
(Dimer_Tnp_hAT)
PF10683
(DBD_Tnp_Hermes) 		4 VAL A 137
VAL A 135
PHE B 123
ARG B  81
 None
 1.15A 3bjwB-2bw3A:
undetectable		 3bjwB-2bw3A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f2e PA1607

(Pseudomonas
aeruginosa) 		PF01638
(HxlR) 		4 VAL A  62
VAL A  68
PHE A  40
ARG A  87
 None
 1.30A 3bjwB-2f2eA:
undetectable		 3bjwB-2f2eA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ffh PROTEIN (FFH)

(Thermus
aquaticus) 		PF00448
(SRP54)
PF02881
(SRP54_N)
PF02978
(SRP_SPB) 		4 VAL A 217
VAL A 243
PHE A 102
ARG A 260
 None
 1.26A 3bjwB-2ffhA:
1.7		 3bjwB-2ffhA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hjg GTP-BINDING PROTEIN
ENGA

(Bacillus
subtilis) 		PF01926
(MMR_HSR1)
PF14714
(KH_dom-like) 		4 VAL A  85
VAL A   6
PHE A  88
ARG A  41
 None
 1.05A 3bjwB-2hjgA:
undetectable		 3bjwB-2hjgA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hlp MALATE DEHYDROGENASE

(Haloarcula
marismortui) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 VAL A  93
VAL A  94
GLN A 124
PHE A 163
 None
 1.34A 3bjwB-2hlpA:
undetectable		 3bjwB-2hlpA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ho4 HALOACID
DEHALOGENASE-LIKE
HYDROLASE DOMAIN
CONTAINING 2

(Mus musculus) 		PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6) 		4 VAL A 176
VAL A 177
GLN A  85
ARG A 190
 None
 1.33A 3bjwB-2ho4A:
undetectable		 3bjwB-2ho4A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lul TYROSINE-PROTEIN
KINASE TEC

(Homo sapiens) 		PF00169
(PH)
PF00779
(BTK) 		4 VAL A  72
VAL A  92
GLN A  26
ARG A  24
 None
 1.36A 3bjwB-2lulA:
undetectable		 3bjwB-2lulA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lv5 UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF10052
(DUF2288) 		4 VAL A  96
VAL A  97
GLN A  99
PHE A  31
 None
 1.33A 3bjwB-2lv5A:
undetectable		 3bjwB-2lv5A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pkq GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
B

(Spinacia
oleracea) 		PF00044
(Gp_dh_N)
PF02672
(CP12)
PF02800
(Gp_dh_C) 		4 VAL O 129
VAL O 130
GLN O 319
PHE O 157
 None
 1.38A 3bjwB-2pkqO:
undetectable		 3bjwB-2pkqO:
16.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		4 VAL A   2
VAL A   3
GLN A  11
PHE A  19
 None
 0.56A 3bjwB-2qheA:
24.1		 3bjwB-2qheA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r7d RIBONUCLEASE II
FAMILY PROTEIN

(Deinococcus
radiodurans) 		PF00773
(RNB) 		4 VAL A 410
VAL A 411
GLN A 431
ARG A 415
 None
 1.36A 3bjwB-2r7dA:
undetectable		 3bjwB-2r7dA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y05 PROSTAGLANDIN
REDUCTASE 1

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		4 VAL A 169
VAL A 170
GLN A 229
PHE A 215
 None
 1.35A 3bjwB-2y05A:
undetectable		 3bjwB-2y05A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zb3 PROSTAGLANDIN
REDUCTASE 2

(Mus musculus) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		4 VAL A 183
VAL A 184
GLN A 243
PHE A 229
 None
 1.27A 3bjwB-2zb3A:
undetectable		 3bjwB-2zb3A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zb4 PROSTAGLANDIN
REDUCTASE 2

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		4 VAL A 183
VAL A 184
GLN A 243
PHE A 229
 None
 1.33A 3bjwB-2zb4A:
undetectable		 3bjwB-2zb4A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyv TYROSINE-ESTER
SULFOTRANSFERASE

(Mus musculus) 		PF00685
(Sulfotransfer_1) 		4 VAL X 135
VAL X 136
GLN X 144
PHE X 169
 None
 1.05A 3bjwB-2zyvX:
undetectable		 3bjwB-2zyvX:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a8r PUTATIVE
UNCHARACTERIZED
PROTEIN

(Oryza sativa) 		PF08414
(NADPH_Ox)
PF13499
(EF-hand_7) 		4 VAL A 176
VAL A 173
GLN A 170
PHE A 182
 None
 1.26A 3bjwB-3a8rA:
undetectable		 3bjwB-3a8rA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9e CHITINASE A

(Vibrio harveyi) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		4 VAL A 225
VAL A 226
GLN A 214
PHE A 192
 None
 1.30A 3bjwB-3b9eA:
undetectable		 3bjwB-3b9eA:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bs6 INNER MEMBRANE
PROTEIN OXAA

(Escherichia
coli) 		PF14849
(YidC_periplas) 		4 VAL A 253
GLN A 198
PHE A 193
ARG A 219
 None
None
PG4  A 336 (-3.9A)
None
 1.25A 3bjwB-3bs6A:
undetectable		 3bjwB-3bs6A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bwl SENSOR PROTEIN

(Haloarcula
marismortui) 		PF08448
(PAS_4) 		4 VAL A 486
GLN A 460
PHE A 448
ARG A 470
 None
 1.34A 3bjwB-3bwlA:
undetectable		 3bjwB-3bwlA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cpg UNCHARACTERIZED
PROTEIN

(Bifidobacterium
adolescentis) 		PF01168
(Ala_racemase_N) 		4 VAL A 134
VAL A 131
GLN A  81
ARG A  79
 None
 1.39A 3bjwB-3cpgA:
undetectable		 3bjwB-3cpgA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos taurus) 		PF13472
(Lipase_GDSL_2) 		4 VAL A  98
VAL A  97
GLN A 130
ARG A  93
 None
 1.30A 3bjwB-3dt8A:
undetectable		 3bjwB-3dt8A:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gcw PROPROTEIN
CONVERTASE
SUBTILISIN/KEXIN
TYPE 9

(Homo sapiens) 		PF00082
(Peptidase_S8) 		4 VAL A 182
VAL A 284
GLN A 275
ARG A 272
 None
 1.40A 3bjwB-3gcwA:
0.7		 3bjwB-3gcwA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhs PHENOLOXIDASE
SUBUNIT 2

(Manduca sexta) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 VAL A 264
GLN A 416
PHE A 267
ARG A 528
 None
 1.30A 3bjwB-3hhsA:
undetectable		 3bjwB-3hhsA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4x TRYPTOPHAN
DIMETHYLALLYLTRANSFE
RASE

(Aspergillus
fumigatus) 		PF11991
(Trp_DMAT) 		4 VAL A 211
GLN A 335
PHE A 141
ARG A 220
 None
 1.22A 3bjwB-3i4xA:
undetectable		 3bjwB-3i4xA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ki8 BETA
UREIDOPROPIONASE
(BETA-ALANINE
SYNTHASE)

(Pyrococcus
abyssi) 		PF00795
(CN_hydrolase) 		4 VAL A  39
VAL A  38
GLN A  36
PHE A 134
 None
 1.32A 3bjwB-3ki8A:
undetectable		 3bjwB-3ki8A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3njp EPIDERMAL GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain)
PF14843
(GF_recep_IV) 		4 VAL A  37
VAL A  36
GLN A  81
PHE A  54
 None
 1.34A 3bjwB-3njpA:
undetectable		 3bjwB-3njpA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE

(Amycolatopsis
sp. ATCC 39116) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 167
VAL A 166
GLN A 260
ARG A 206
 None
 1.37A 3bjwB-3t9wA:
undetectable		 3bjwB-3t9wA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tdg PUTATIVE
UNCHARACTERIZED
PROTEIN

(Helicobacter
pylori) 		no annotation 4 VAL A 183
VAL A 182
GLN A 163
PHE A 259
 None
 1.33A 3bjwB-3tdgA:
undetectable		 3bjwB-3tdgA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tg9 PENICILLIN-BINDING
PROTEIN

(Bacillus
halodurans) 		PF00144
(Beta-lactamase) 		4 VAL A 165
VAL A 162
GLN A  65
ARG A 181
 None
 1.32A 3bjwB-3tg9A:
undetectable		 3bjwB-3tg9A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tl3 SHORT-CHAIN TYPE
DEHYDROGENASE/REDUCT
ASE

(Mycobacterium
ulcerans) 		PF00106
(adh_short) 		4 VAL A  79
VAL A   9
GLN A  31
ARG A  49
 None
 1.28A 3bjwB-3tl3A:
undetectable		 3bjwB-3tl3A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u3x OXIDOREDUCTASE

(Sinorhizobium
meliloti) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 VAL A 257
GLN A 351
PHE A 211
ARG A 193
 None
 1.37A 3bjwB-3u3xA:
undetectable		 3bjwB-3u3xA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vbc INTERLEUKIN-17
RECEPTOR B

(Mus musculus) 		PF08357
(SEFIR) 		4 VAL A 390
VAL A 333
GLN A 382
PHE A 424
 None
 1.25A 3bjwB-3vbcA:
undetectable		 3bjwB-3vbcA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vi3 INTEGRIN ALPHA-5

(Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 VAL A 435
VAL A 444
GLN A  66
PHE A 438
 None
 1.28A 3bjwB-3vi3A:
undetectable		 3bjwB-3vi3A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vxi DYP

(Bjerkandera
adusta) 		PF04261
(Dyp_perox) 		4 VAL A 191
VAL A 178
GLN A 175
ARG A 329
 None
None
None
HEM  A 501 (-3.1A)
 1.24A 3bjwB-3vxiA:
undetectable		 3bjwB-3vxiA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w0f ENDONUCLEASE 8-LIKE
3

(Mus musculus) 		PF06831
(H2TH) 		4 VAL A  27
VAL A 122
GLN A  22
ARG A 126
 None
 1.19A 3bjwB-3w0fA:
undetectable		 3bjwB-3w0fA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE

(Clostridium
tetani) 		PF16654
(DAPDH_C) 		4 VAL A  90
GLN A  79
PHE A 103
ARG A  37
 None
 1.15A 3bjwB-3wgoA:
undetectable		 3bjwB-3wgoA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a6u OMEGA TRANSAMINASE

(Chromobacterium
violaceum) 		PF00202
(Aminotran_3) 		4 VAL A 257
VAL A 224
GLN A 229
PHE A 272
 None
 1.33A 3bjwB-4a6uA:
0.3		 3bjwB-4a6uA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4boc DNA-DIRECTED RNA
POLYMERASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00940
(RNA_pol)
PF14700
(RPOL_N) 		4 VAL A 963
VAL A 965
GLN A 972
PHE A 984
 None
 1.40A 3bjwB-4bocA:
undetectable		 3bjwB-4bocA:
6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cxh ELONGATION FACTOR 1A

(Oryctolagus
cuniculus) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2) 		4 VAL A  11
VAL A  10
GLN A 238
ARG A 309
 None
 1.18A 3bjwB-4cxhA:
undetectable		 3bjwB-4cxhA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dal PUTATIVE ALDEHYDE
DEHYDROGENASE

(Sinorhizobium
meliloti) 		PF00171
(Aldedh) 		4 VAL A 384
VAL A 383
GLN A 361
ARG A 351
 None
 1.14A 3bjwB-4dalA:
undetectable		 3bjwB-4dalA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4glw DNA LIGASE

(Streptococcus
pneumoniae) 		PF01653
(DNA_ligase_aden) 		4 VAL A 275
VAL A 276
GLN A  80
ARG A  94
 None
0XT  A 402 (-4.6A)
None
None
 1.35A 3bjwB-4glwA:
undetectable		 3bjwB-4glwA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hw6 HYPOTHETICAL
PROTEIN, IPT/TIG
DOMAIN PROTEIN

(Bacteroides
ovatus) 		PF01833
(TIG) 		4 VAL A 311
GLN A 270
PHE A 221
ARG A 336
 CL  A 507 ( 4.2A)
None
None
None
 1.27A 3bjwB-4hw6A:
undetectable		 3bjwB-4hw6A:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j72 PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE

(Aquifex
aeolicus) 		PF00953
(Glycos_transf_4)
PF10555
(MraY_sig1) 		4 VAL A 213
VAL A 212
PHE A 288
ARG A  25
 None
 1.31A 3bjwB-4j72A:
undetectable		 3bjwB-4j72A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jgb PUTATIVE EXPORTED
PROTEIN

(Burkholderia
pseudomallei) 		PF13460
(NAD_binding_10) 		4 VAL A  64
VAL A  65
PHE A 150
ARG A  91
 None
 1.16A 3bjwB-4jgbA:
undetectable		 3bjwB-4jgbA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lk2 PRE-MRNA-PROCESSING
ATP-DEPENDENT RNA
HELICASE PRP5

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 VAL A 386
VAL A 385
PHE A 353
ARG A 380
 None
 1.20A 3bjwB-4lk2A:
undetectable		 3bjwB-4lk2A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m9p FILAMIN-A

(Homo sapiens) 		PF00630
(Filamin) 		4 VAL A 599
VAL A 598
GLN A 710
ARG A 708
 None
 1.36A 3bjwB-4m9pA:
undetectable		 3bjwB-4m9pA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n06 CRISPR-ASSOCIATED
ENDONUCLEASE CAS1 1

(Archaeoglobus
fulgidus) 		PF01867
(Cas_Cas1) 		4 VAL A 226
VAL A 223
GLN A  38
ARG A   2
 None
 1.32A 3bjwB-4n06A:
undetectable		 3bjwB-4n06A:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nho PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX23

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 VAL A 547
VAL A 603
GLN A 575
ARG A 622
 None
 1.39A 3bjwB-4nhoA:
undetectable		 3bjwB-4nhoA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o26 TELOMERASE REVERSE
TRANSCRIPTASE

(Oryzias latipes) 		PF12009
(Telomerase_RBD) 		4 VAL A 350
GLN A 510
PHE A 519
ARG A 506
 None
None
None
U  E 182 ( 4.0A)
 1.38A 3bjwB-4o26A:
undetectable		 3bjwB-4o26A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qbo NUCLEASE

(Streptococcus
phage P9) 		PF08774
(VRR_NUC) 		4 VAL A  74
GLN A  57
PHE A  42
ARG A  54
 None
 1.28A 3bjwB-4qboA:
undetectable		 3bjwB-4qboA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ri0 SERINE PROTEASE
HTRA3

(Homo sapiens) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		4 VAL A 192
VAL A 193
GLN A 203
ARG A 360
 None
 1.27A 3bjwB-4ri0A:
undetectable		 3bjwB-4ri0A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rmf ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Mycolicibacterium
smegmatis) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
PF02938
(GAD) 		4 VAL A 419
VAL A 420
PHE A 416
ARG A 489
 None
None
None
FMT  A 702 (-2.7A)
 1.31A 3bjwB-4rmfA:
undetectable		 3bjwB-4rmfA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rv0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
TER94

(Drosophila
melanogaster) 		PF02359
(CDC48_N)
PF02933
(CDC48_2) 		4 VAL A  84
VAL A  85
PHE A 160
ARG A  60
 None
 1.28A 3bjwB-4rv0A:
undetectable		 3bjwB-4rv0A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rzi 3-KETOACYL-ACYL
CARRIER PROTEIN
REDUCTASE

(Synechocystis
sp. PCC 6803) 		no annotation 4 VAL B  10
VAL B  76
PHE B  37
ARG B 171
 None
 1.29A 3bjwB-4rziB:
undetectable		 3bjwB-4rziB:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3h MDB1

(Schizosaccharomyces
pombe) 		no annotation 4 VAL A  61
VAL A  54
PHE A  46
ARG A  51
 None
 1.39A 3bjwB-4s3hA:
undetectable		 3bjwB-4s3hA:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tvv TYROSINE PHOSPHATASE
II SUPERFAMILY
PROTEIN

(Legionella
pneumophila) 		PF14566
(PTPlike_phytase) 		4 VAL A  49
GLN A  79
PHE A  46
ARG A 109
 None
 1.28A 3bjwB-4tvvA:
undetectable		 3bjwB-4tvvA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uvq THIAZOLINE
OXIDASE/SUBTILISIN-L
IKE PROTEASE

(Prochloron sp.) 		no annotation 4 VAL A1036
VAL A1037
GLN A1094
ARG A1024
 None
 1.32A 3bjwB-4uvqA:
undetectable		 3bjwB-4uvqA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uw9 BETA-PHOSPHOGLUCOMUT
ASE

(Pyrococcus sp.
ST04) 		PF13419
(HAD_2) 		4 VAL A 177
VAL A 176
PHE A   8
ARG A 185
 None
 0.96A 3bjwB-4uw9A:
undetectable		 3bjwB-4uw9A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w1w ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE

(Mycobacterium
tuberculosis) 		PF00202
(Aminotran_3) 		4 VAL A 218
VAL A 219
GLN A 190
ARG A 230
 None
 1.29A 3bjwB-4w1wA:
undetectable		 3bjwB-4w1wA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xx6 BETA-XYLANASE

(Gloeophyllum
trabeum) 		PF00331
(Glyco_hydro_10) 		4 VAL A 290
VAL A 289
GLN A 281
PHE A 338
 None
 1.10A 3bjwB-4xx6A:
undetectable		 3bjwB-4xx6A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE

(Moraxella
catarrhalis) 		PF02670
(DXP_reductoisom)
PF08436
(DXP_redisom_C)
PF13288
(DXPR_C) 		4 VAL A 259
GLN A 161
PHE A 270
ARG A 292
 None
 1.39A 3bjwB-4zqgA:
2.4		 3bjwB-4zqgA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b2d HN PROTEIN

(Mumps
rubulavirus) 		PF00423
(HN) 		4 VAL A 395
VAL A 396
GLN A 421
PHE A 320
 None
 1.30A 3bjwB-5b2dA:
undetectable		 3bjwB-5b2dA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c92 KELCH
DOMAIN-CONTAINING
PROTEIN

(Colletotrichum
graminicola) 		PF01344
(Kelch_1)
PF09118
(DUF1929) 		4 VAL A  19
VAL A  30
GLN A  65
PHE A  72
 None
None
None
CU1  A 503 (-4.4A)
 1.07A 3bjwB-5c92A:
undetectable		 3bjwB-5c92A:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5efv PHI ETA ORF 56-LIKE
PROTEIN

(Staphylococcus
virus 11) 		no annotation 4 VAL A 426
GLN A 148
PHE A 152
ARG A 142
 None
 0.87A 3bjwB-5efvA:
undetectable		 3bjwB-5efvA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ej1 PUTATIVE CELLULOSE
SYNTHASE

(Rhodobacter
sphaeroides) 		PF00535
(Glycos_transf_2)
PF03552
(Cellulose_synt)
PF07238
(PilZ) 		4 VAL A  51
VAL A  50
GLN A  42
ARG A  79
 None
 1.34A 3bjwB-5ej1A:
undetectable		 3bjwB-5ej1A:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fir 5'-3'
EXORIBONUCLEASE 2
HOMOLOG

(Caenorhabditis
elegans) 		PF03159
(XRN_N) 		4 VAL A  18
VAL A  19
GLN A  46
PHE A 300
 None
 1.34A 3bjwB-5firA:
undetectable		 3bjwB-5firA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gyq SPIKE GLYCOPROTEIN

(Rousettus bat
coronavirus
HKU9) 		PF09408
(Spike_rec_bind) 		4 VAL A  22
VAL A  23
PHE A 121
ARG A  26
 None
 1.12A 3bjwB-5gyqA:
undetectable		 3bjwB-5gyqA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjp NONRIBOSOMAL PEPTIDE
SYNTHASE

(Streptomyces
sp. MJ635-86F5) 		PF00501
(AMP-binding) 		4 VAL A  71
VAL A  72
GLN A 121
PHE A  85
 None
 1.39A 3bjwB-5jjpA:
undetectable		 3bjwB-5jjpA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ktk POLYKETIDE SYNTHASE
PKSJ

(Bacillus
subtilis) 		PF08659
(KR) 		4 VAL A 409
VAL A 456
GLN A 401
PHE A 365
 None
 1.22A 3bjwB-5ktkA:
undetectable		 3bjwB-5ktkA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lj6 MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB

(Aggregatibacter
actinomycetemcomitans) 		no annotation 4 VAL A 285
VAL A 286
GLN A 293
PHE A 526
 None
 1.38A 3bjwB-5lj6A:
1.8		 3bjwB-5lj6A:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5my0 FATTY ACID SYNTHASE

(Mus musculus) 		no annotation 5 VAL B 532
VAL B 527
GLN B 596
PHE B 553
ARG B 522
 None
 1.50A 3bjwB-5my0B:
undetectable		 3bjwB-5my0B:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB

(Saccharomyces
cerevisiae) 		no annotation 4 VAL 7 657
GLN 7 672
PHE 7 626
ARG 7 722
 None
 0.97A 3bjwB-5oqm7:
undetectable		 3bjwB-5oqm7:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5owj TRIGGER FACTOR

(Escherichia
coli) 		no annotation 4 VAL A 258
GLN A 191
PHE A 252
ARG A 193
 None
 1.20A 3bjwB-5owjA:
undetectable		 3bjwB-5owjA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sui RIBOSOME BIOGENESIS
PROTEIN NSA1

(Saccharomyces
cerevisiae) 		no annotation 4 VAL A 313
VAL A 338
GLN A 310
PHE A 258
 None
 1.35A 3bjwB-5suiA:
undetectable		 3bjwB-5suiA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uz5 56 KDA U1 SMALL
NUCLEAR
RIBONUCLEOPROTEIN
COMPONENT
U1 SMALL NUCLEAR
RIBONUCLEOPROTEIN
COMPONENT PRP42

(Saccharomyces
cerevisiae) 		no annotation 4 VAL G 195
VAL G 194
PHE G 161
ARG D 104
 None
 1.14A 3bjwB-5uz5G:
undetectable		 3bjwB-5uz5G:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vh1 GAMMA S-CRYSTALLIN

(Gallus gallus) 		PF00030
(Crystall) 		4 VAL A  60
VAL A  47
PHE A 138
ARG A  51
 None
 1.07A 3bjwB-5vh1A:
undetectable		 3bjwB-5vh1A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vvh OCTOPINE
CATABOLISM/UPTAKE
OPERON REGULATORY
PROTEIN OCCR

(Agrobacterium
tumefaciens) 		PF03466
(LysR_substrate) 		4 VAL A 165
VAL A 166
PHE A 257
ARG A 212
 None
 1.30A 3bjwB-5vvhA:
undetectable		 3bjwB-5vvhA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w25 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Mycobacterium
tuberculosis) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
PF02938
(GAD) 		4 VAL A 422
VAL A 423
PHE A 419
ARG A 492
 None
None
None
ASP  A 701 (-2.9A)
 1.31A 3bjwB-5w25A:
undetectable		 3bjwB-5w25A:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xgu RIBONUCLEASE R

(Escherichia
coli) 		no annotation 4 VAL B 107
VAL B 108
GLN B  96
PHE B 104
 None
 1.36A 3bjwB-5xguB:
undetectable		 3bjwB-5xguB:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r DNA-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08163
(NUC194) 		4 VAL C 483
VAL C 482
PHE C 551
ARG C1806
 None
 1.03A 3bjwB-5y3rC:
undetectable		 3bjwB-5y3rC:
2.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ybb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Caldanaerobacter
subterraneus) 		no annotation 4 VAL A 181
VAL A 182
GLN A 188
PHE A 373
 None
 1.24A 3bjwB-5ybbA:
undetectable		 3bjwB-5ybbA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yht HISTIDINOL-PHOSPHATA
SE

(Mycobacterium
tuberculosis) 		no annotation 4 VAL A 201
VAL A 196
PHE A 159
ARG A 227
 None
 1.34A 3bjwB-5yhtA:
1.8		 3bjwB-5yhtA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cv6 3-DEHYDROQUINATE
DEHYDRATASE

(Paraburkholderia
phymatum) 		no annotation 4 VAL A 120
VAL A 121
GLN A 143
PHE A  65
 None
 1.34A 3bjwB-6cv6A:
undetectable		 3bjwB-6cv6A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dhi -

(-) 		no annotation 4 VAL A 300
VAL A 299
GLN A 278
PHE A 202
 None
 1.40A 3bjwB-6dhiA:
undetectable		 3bjwB-6dhiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6egx STRUCTURAL PROTEIN
VP1
STRUCTURAL PROTEIN
VP2

(Sacbrood virus) 		no annotation 4 VAL A 176
GLN B 138
PHE B 134
ARG A 184
 None
 1.40A 3bjwB-6egxA:
undetectable		 3bjwB-6egxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fao GLYCOSIDE HYDROLASE
FAMILY 6

(metagenome) 		no annotation 4 VAL A 217
VAL A 218
PHE A 156
ARG A 222
 None
 1.26A 3bjwB-6faoA:
undetectable		 3bjwB-6faoA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ftx -

(-) 		no annotation 4 VAL W 412
VAL W 409
PHE W 370
ARG W 597
 None
 1.28A 3bjwB-6ftxW:
undetectable		 3bjwB-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1asx THERMOSOME

(Thermoplasma
acidophilum) 		PF00118
(Cpn60_TCP1) 		3 PRO A  47
PHE A  53
LYS A  49
 None
 1.22A 3bjwG-1asxA:
undetectable		 3bjwG-1asxA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dgv APO CIB

(Homo sapiens) 		PF13499
(EF-hand_7) 		3 PRO A  31
PHE A  83
LYS A   1
 None
 1.24A 3bjwG-1dgvA:
0.0		 3bjwG-1dgvA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e9y UREASE SUBUNIT BETA

(Helicobacter
pylori) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		3 PRO B 413
PHE B 529
LYS B 408
 None
 1.26A 3bjwG-1e9yB:
1.2		 3bjwG-1e9yB:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eyp CHALCONE-FLAVONONE
ISOMERASE 1

(Medicago sativa) 		PF02431
(Chalcone) 		3 PRO A 146
PHE A  47
LYS A  97
 None
 0.99A 3bjwG-1eypA:
0.0		 3bjwG-1eypA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 PRO A 223
PHE A 290
LYS A 226
 None
 1.19A 3bjwG-1fcpA:
0.0		 3bjwG-1fcpA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fgv H52 FV (LIGHT CHAIN)

(Homo sapiens) 		PF07686
(V-set) 		3 PRO L   8
PHE L  83
LYS L 103
 PRO  L   8 ( 1.0A)
PHE  L  83 ( 1.3A)
LYS  L 103 ( 0.0A)
 1.25A 3bjwG-1fgvL:
0.0		 3bjwG-1fgvL:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gzv GLUCOSE-6-PHOSPHATE
ISOMERASE

(Sus scrofa) 		PF00342
(PGI) 		3 PRO A 316
PHE A 351
LYS A 496
 None
 1.20A 3bjwG-1gzvA:
0.5		 3bjwG-1gzvA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j6o TATD-RELATED
DEOXYRIBONUCLEASE

(Thermotoga
maritima) 		PF01026
(TatD_DNase) 		3 PRO A 144
PHE A 250
LYS A 146
 None
 1.10A 3bjwG-1j6oA:
0.0		 3bjwG-1j6oA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kb0 QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Comamonas
testosteroni) 		PF13360
(PQQ_2)
PF13442
(Cytochrome_CBB3) 		3 PRO A 641
PHE A 650
LYS A 639
 HEC  A 802 (-3.9A)
HEC  A 802 (-3.6A)
None
 1.24A 3bjwG-1kb0A:
0.0		 3bjwG-1kb0A:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l0w ASPARTYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
PF02938
(GAD) 		3 PRO A 557
PHE A 548
LYS A 550
 None
 1.19A 3bjwG-1l0wA:
undetectable		 3bjwG-1l0wA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ldn L-LACTATE
DEHYDROGENASE

(Geobacillus
stearothermophilus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		3 PRO A  73
PHE A  65
LYS A  69
 None
 0.99A 3bjwG-1ldnA:
undetectable		 3bjwG-1ldnA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mw9 DNA TOPOISOMERASE I

(Escherichia
coli) 		PF01131
(Topoisom_bac)
PF01751
(Toprim) 		3 PRO X 349
PHE X 343
LYS X 346
 None
 1.27A 3bjwG-1mw9X:
undetectable		 3bjwG-1mw9X:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nf9 PHENAZINE
BIOSYNTHESIS PROTEIN
PHZD

(Pseudomonas
aeruginosa) 		PF00857
(Isochorismatase) 		3 PRO A  79
PHE A 129
LYS A 122
 None
 0.93A 3bjwG-1nf9A:
undetectable		 3bjwG-1nf9A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qq6 PROTEIN
(L-2-HALOACID
DEHALOGENASE)

(Xanthobacter
autotrophicus) 		PF00702
(Hydrolase) 		3 PRO A  94
PHE A   7
LYS A   9
 None
None
ASB  A   8 ( 3.3A)
 1.22A 3bjwG-1qq6A:
undetectable		 3bjwG-1qq6A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1stz HEAT-INDUCIBLE
TRANSCRIPTION
REPRESSOR HRCA
HOMOLOG

(Thermotoga
maritima) 		PF01628
(HrcA) 		3 PRO A  79
PHE A  86
LYS A  82
 None
 1.23A 3bjwG-1stzA:
undetectable		 3bjwG-1stzA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tvc METHANE
MONOOXYGENASE
COMPONENT C

(Methylococcus
capsulatus) 		PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		3 PRO A 219
PHE A 242
LYS A 244
 None
 0.97A 3bjwG-1tvcA:
undetectable		 3bjwG-1tvcA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vg0 RAB PROTEINS
GERANYLGERANYLTRANSF
ERASE COMPONENT A 1

(Rattus
norvegicus) 		PF00996
(GDI) 		3 PRO A 475
PHE A 317
LYS A 343
 None
 1.24A 3bjwG-1vg0A:
undetectable		 3bjwG-1vg0A:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfu CALMODULIN-SENSITIVE
ADENYLATE CYCLASE

(Bacillus
anthracis) 		PF03497
(Anthrax_toxA)
PF07737
(ATLF) 		3 PRO A 190
PHE A 229
LYS A 231
 None
 1.26A 3bjwG-1xfuA:
undetectable		 3bjwG-1xfuA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ye9 CATALASE HPII

(Escherichia
coli) 		PF00199
(Catalase) 		3 PRO A 156
PHE A 152
LYS A 158
 None
 1.28A 3bjwG-1ye9A:
undetectable		 3bjwG-1ye9A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b81 LUCIFERASE-LIKE
MONOOXYGENASE

(Bacillus cereus) 		PF00296
(Bac_luciferase) 		3 PRO A 188
PHE A   7
LYS A 190
 None
 1.18A 3bjwG-2b81A:
undetectable		 3bjwG-2b81A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bzn GMP REDUCTASE 2

(Homo sapiens) 		PF00478
(IMPDH) 		3 PRO A 296
PHE A 266
LYS A 264
 None
 1.17A 3bjwG-2bznA:
undetectable		 3bjwG-2bznA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ddt SPHINGOMYELIN
PHOSPHODIESTERASE

(Bacillus cereus) 		PF03372
(Exo_endo_phos) 		3 PRO A 264
PHE A 215
LYS A 259
 None
 0.70A 3bjwG-2ddtA:
undetectable		 3bjwG-2ddtA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dgu HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN Q

(Homo sapiens) 		PF00076
(RRM_1) 		3 PRO A 409
PHE A 405
LYS A 407
 None
 1.04A 3bjwG-2dguA:
undetectable		 3bjwG-2dguA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ex3 DNA TERMINAL PROTEIN

(Bacillus virus
phi29) 		PF05435
(Phi-29_GP3) 		3 PRO B 145
PHE B 148
LYS B  99
 None
 1.21A 3bjwG-2ex3B:
undetectable		 3bjwG-2ex3B:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i04 MEMBRANE-ASSOCIATED
GUANYLATE KINASE, WW
AND PDZ
DOMAIN-CONTAINING
PROTEIN 1

(Mus musculus) 		PF00595
(PDZ) 		3 PRO A 486
PHE A 519
LYS A 457
 None
 1.27A 3bjwG-2i04A:
undetectable		 3bjwG-2i04A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j0w LYSINE-SENSITIVE
ASPARTOKINASE 3

(Escherichia
coli) 		PF00696
(AA_kinase)
PF01842
(ACT) 		3 PRO A 231
PHE A 448
LYS A 238
 None
 1.13A 3bjwG-2j0wA:
0.0		 3bjwG-2j0wA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lju PUTATIVE
OXIDOREDUCTASE

(Ehrlichia
chaffeensis) 		PF04800
(ETC_C1_NDUFA4) 		3 PRO A  15
PHE A  62
LYS A  28
 None
 1.26A 3bjwG-2ljuA:
undetectable		 3bjwG-2ljuA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oew PROGRAMMED CELL
DEATH 6-INTERACTING
PROTEIN

(Homo sapiens) 		PF03097
(BRO1) 		3 PRO A  83
PHE A 355
LYS A  81
 None
 1.16A 3bjwG-2oewA:
1.1		 3bjwG-2oewA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2orz NEUROPILIN-1

(Rattus
norvegicus) 		PF00754
(F5_F8_type_C) 		3 PRO A 566
PHE A 540
LYS A 514
 None
 1.13A 3bjwG-2orzA:
undetectable		 3bjwG-2orzA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pby GLUTAMINASE

(Geobacillus
kaustophilus) 		PF04960
(Glutaminase) 		3 PRO A 257
PHE A 237
LYS A 259
 None
 1.28A 3bjwG-2pbyA:
undetectable		 3bjwG-2pbyA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qf7 PYRUVATE CARBOXYLASE
PROTEIN

(Rhizobium etli) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF00682
(HMGL-like)
PF02436
(PYC_OADA)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		3 PRO A 883
PHE A 875
LYS A 880
 None
 1.28A 3bjwG-2qf7A:
undetectable		 3bjwG-2qf7A:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qqk NEUROPILIN-2

(Homo sapiens) 		PF00431
(CUB)
PF00754
(F5_F8_type_C) 		3 PRO A 546
PHE A 563
LYS A 547
 None
 1.23A 3bjwG-2qqkA:
undetectable		 3bjwG-2qqkA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qqo NEUROPILIN-2

(Homo sapiens) 		PF00431
(CUB)
PF00754
(F5_F8_type_C) 		3 PRO A 546
PHE A 563
LYS A 547
 None
 1.20A 3bjwG-2qqoA:
undetectable		 3bjwG-2qqoA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rv1 ZINC FINGER PROTEIN
ZFAT

(Homo sapiens) 		no annotation 3 PRO A  13
PHE A  17
LYS A  11
 None
 1.28A 3bjwG-2rv1A:
undetectable		 3bjwG-2rv1A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wzg GLUCOSYLTRANSFERASE

(Legionella
pneumophila) 		PF16849
(Glyco_transf_88) 		3 PRO A 522
PHE A 439
LYS A 441
 None
 1.26A 3bjwG-2wzgA:
undetectable		 3bjwG-2wzgA:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yax SULFUR
OXYGENASE/REDUCTASE

(Acidianus
ambivalens) 		PF07682
(SOR) 		3 PRO B   4
PHE B  40
LYS B  81
 None
 1.21A 3bjwG-2yaxB:
undetectable		 3bjwG-2yaxB:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b0h NITRITE REDUCTASE

(Nicotiana
tabacum) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		3 PRO A 222
PHE A 264
LYS A 224
 None
None
SRM  A 601 (-2.6A)
 1.07A 3bjwG-3b0hA:
undetectable		 3bjwG-3b0hA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxv SULFUR
OXYGENASE/REDUCTASE

(Acidianus
tengchongensis) 		PF07682
(SOR) 		3 PRO A   4
PHE A  40
LYS A  81
 None
 1.15A 3bjwG-3bxvA:
undetectable		 3bjwG-3bxvA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eaf ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Aeropyrum
pernix) 		PF13458
(Peripla_BP_6) 		3 PRO A 297
PHE A 410
LYS A 392
 None
 1.28A 3bjwG-3eafA:
undetectable		 3bjwG-3eafA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fcx S-FORMYLGLUTATHIONE
HYDROLASE

(Homo sapiens) 		PF00756
(Esterase) 		3 PRO A  81
PHE A  19
LYS A  31
 None
 1.19A 3bjwG-3fcxA:
undetectable		 3bjwG-3fcxA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fo8 TAIL SHEATH PROTEIN
GP18

(Escherichia
virus T4) 		PF17481
(Phage_sheath_1N) 		3 PRO D 331
PHE D 210
LYS D 215
 None
 1.14A 3bjwG-3fo8D:
undetectable		 3bjwG-3fo8D:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3foa TAIL SHEATH PROTEIN
GP18

(Escherichia
virus T4) 		PF04984
(Phage_sheath_1)
PF17481
(Phage_sheath_1N) 		3 PRO A 331
PHE A 210
LYS A 215
 None
 1.23A 3bjwG-3foaA:
undetectable		 3bjwG-3foaA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fqd PROTEIN DIN1

(Schizosaccharomyces
pombe) 		PF08652
(RAI1) 		3 PRO B 177
PHE B  58
LYS B 148
 None
 1.01A 3bjwG-3fqdB:
undetectable		 3bjwG-3fqdB:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h4p PROTEASOME SUBUNIT
BETA

(Methanocaldococcus
jannaschii) 		PF00227
(Proteasome)
PF10584
(Proteasome_A_N) 		3 PRO a 141
PHE a 177
LYS a   7
 None
 0.99A 3bjwG-3h4pa:
1.1		 3bjwG-3h4pa:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hjb GLUCOSE-6-PHOSPHATE
ISOMERASE

(Vibrio cholerae) 		PF00342
(PGI) 		3 PRO A 315
PHE A 350
LYS A 493
 None
 1.26A 3bjwG-3hjbA:
undetectable		 3bjwG-3hjbA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3icy SENSOR PROTEIN

(Chlorobaculum
tepidum) 		PF08447
(PAS_3) 		3 PRO A  83
PHE A  32
LYS A  86
 None
 1.14A 3bjwG-3icyA:
undetectable		 3bjwG-3icyA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j2n TAIL SHEATH PROTEIN
GP18

(Escherichia
virus T4) 		PF04984
(Phage_sheath_1)
PF17481
(Phage_sheath_1N)
PF17482
(Phage_sheath_1C) 		3 PRO U 331
PHE U 210
LYS U 215
 None
 1.23A 3bjwG-3j2nU:
undetectable		 3bjwG-3j2nU:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l82 F-BOX ONLY PROTEIN 4

(Homo sapiens) 		no annotation 3 PRO B 177
PHE B 223
LYS B 230
 None
 1.20A 3bjwG-3l82B:
undetectable		 3bjwG-3l82B:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nbu GLUCOSE-6-PHOSPHATE
ISOMERASE

(Escherichia
coli) 		PF00342
(PGI) 		3 PRO A 314
PHE A 349
LYS A 492
 None
 1.19A 3bjwG-3nbuA:
undetectable		 3bjwG-3nbuA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p8c NCK-ASSOCIATED
PROTEIN 1

(Homo sapiens) 		PF09735
(Nckap1) 		3 PRO B 188
PHE B 196
LYS B 191
 None
 1.24A 3bjwG-3p8cB:
undetectable		 3bjwG-3p8cB:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q5t TCR N30 BETA

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 PRO A 130
PHE A 196
LYS A 140
 None
 1.07A 3bjwG-3q5tA:
undetectable		 3bjwG-3q5tA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r2g INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE

(Legionella
pneumophila) 		PF00478
(IMPDH) 		3 PRO A 283
PHE A 242
LYS A 249
 None
 1.25A 3bjwG-3r2gA:
undetectable		 3bjwG-3r2gA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r77 PROBABLE
ISOCHORISMATASE

(Pseudomonas
fluorescens) 		PF00857
(Isochorismatase) 		3 PRO A  79
PHE A 129
LYS A 122
 None
None
QLI  A 500 (-2.6A)
 1.02A 3bjwG-3r77A:
undetectable		 3bjwG-3r77A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t05 PYRUVATE KINASE

(Staphylococcus
aureus) 		PF00224
(PK)
PF00391
(PEP-utilizers)
PF02887
(PK_C) 		3 PRO A 218
PHE A 193
LYS A 219
 None
 1.28A 3bjwG-3t05A:
undetectable		 3bjwG-3t05A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u4a JMB19063

(compost
metagenome) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		3 PRO A 672
PHE A 613
LYS A 674
 None
 1.17A 3bjwG-3u4aA:
undetectable		 3bjwG-3u4aA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uz0 STAGE II SPORULATION
PROTEIN Q

(Bacillus
subtilis) 		PF01551
(Peptidase_M23) 		3 PRO B  82
PHE B 219
LYS B  78
 None
 1.23A 3bjwG-3uz0B:
undetectable		 3bjwG-3uz0B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vly NITRITE REDUCTASE

(Nicotiana
tabacum) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		3 PRO A 222
PHE A 264
LYS A 224
 None
None
SO3  A 606 ( 2.2A)
 1.01A 3bjwG-3vlyA:
undetectable		 3bjwG-3vlyA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zc4 SSO1398

(Sulfolobus
solfataricus) 		no annotation 3 PRO A 132
PHE A  24
LYS A  20
 None
 0.93A 3bjwG-3zc4A:
undetectable		 3bjwG-3zc4A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zhp CALCIUM-BINDING
PROTEIN 39-LIKE

(Homo sapiens) 		PF08569
(Mo25) 		3 PRO A 289
PHE A 280
LYS A 286
 None
 1.05A 3bjwG-3zhpA:
undetectable		 3bjwG-3zhpA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2w RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16739
(CARD_2) 		3 PRO A 579
PHE A 572
LYS A 576
 None
 1.12A 3bjwG-4a2wA:
1.9		 3bjwG-4a2wA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aco CENTROMERE
DNA-BINDING PROTEIN
COMPLEX CBF3 SUBUNIT
A

(Saccharomyces
cerevisiae) 		PF16787
(NDC10_II) 		3 PRO A 322
PHE A 228
LYS A 233
 None
 1.26A 3bjwG-4acoA:
undetectable		 3bjwG-4acoA:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4du5 PFKB

(Polaromonas sp.
JS666) 		PF00294
(PfkB) 		3 PRO A 127
PHE A  53
LYS A 119
 None
 1.22A 3bjwG-4du5A:
undetectable		 3bjwG-4du5A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eqv INVERTASE 2

(Saccharomyces
cerevisiae) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		3 PRO A 205
PHE A 155
LYS A 153
 None
 0.95A 3bjwG-4eqvA:
undetectable		 3bjwG-4eqvA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo sapiens) 		PF01593
(Amino_oxidase)
PF04433
(SWIRM)
PF07496
(zf-CW) 		3 PRO A 749
PHE A 753
LYS A 751
 None
 1.23A 3bjwG-4hsuA:
undetectable		 3bjwG-4hsuA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mad BETA-GALACTOSIDASE

(Bacillus
circulans) 		PF01301
(Glyco_hydro_35) 		3 PRO A 371
PHE A 101
LYS A 458
 None
 1.15A 3bjwG-4madA:
undetectable		 3bjwG-4madA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o9i CHROMODOMAIN-HELICAS
E-DNA-BINDING
PROTEIN 4

(Homo sapiens) 		PF00385
(Chromo) 		3 PRO X 107
PHE X  67
LYS X  32
 None
 1.14A 3bjwG-4o9iX:
undetectable		 3bjwG-4o9iX:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oy2 TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 1

(Saccharomyces
cerevisiae) 		PF12157
(DUF3591) 		3 PRO A 756
PHE A 480
LYS A 559
 None
 1.21A 3bjwG-4oy2A:
undetectable		 3bjwG-4oy2A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pri TK3 TCR BETA CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 PRO E  25
PHE E 115
LYS E   2
 None
 1.21A 3bjwG-4priE:
undetectable		 3bjwG-4priE:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qdr NEUROPILIN-2

(Homo sapiens) 		PF00754
(F5_F8_type_C) 		3 PRO A 546
PHE A 563
LYS A 547
 None
 1.27A 3bjwG-4qdrA:
undetectable		 3bjwG-4qdrA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qdr NEUROPILIN-2

(Homo sapiens) 		PF00754
(F5_F8_type_C) 		3 PRO A 575
PHE A 549
LYS A 523
 None
 1.25A 3bjwG-4qdrA:
undetectable		 3bjwG-4qdrA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rmf ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Mycolicibacterium
smegmatis) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
PF02938
(GAD) 		3 PRO A 563
PHE A 554
LYS A 556
 None
 1.26A 3bjwG-4rmfA:
undetectable		 3bjwG-4rmfA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E

(Streptococcus
mutans) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 PRO A 163
PHE A 139
LYS A 160
 None
 1.18A 3bjwG-4xb3A:
undetectable		 3bjwG-4xb3A:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xch S-RIBOSYLHOMOCYSTEIN
E LYASE

(Streptococcus
suis) 		PF02664
(LuxS) 		3 PRO A  46
PHE A 155
LYS A  18
 None
 1.14A 3bjwG-4xchA:
undetectable		 3bjwG-4xchA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y05 KINESIN-LIKE PROTEIN
KIF2C

(Homo sapiens) 		PF00225
(Kinesin) 		3 PRO A 284
PHE A 311
LYS A 286
 None
 1.28A 3bjwG-4y05A:
undetectable		 3bjwG-4y05A:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Burkholderia
vietnamiensis) 		PF02350
(Epimerase_2) 		3 PRO A 299
PHE A 286
LYS A 303
 None
 1.21A 3bjwG-5dldA:
undetectable		 3bjwG-5dldA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eio N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE/N-ACET
YL-GAMMA-AMINOADIPYL
-PHOSPHATE REDUCTASE

(Thermus
thermophilus) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		3 PRO A 106
PHE A 101
LYS A 104
 None
 1.24A 3bjwG-5eioA:
undetectable		 3bjwG-5eioA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5emw TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-5

(Homo sapiens) 		no annotation 3 PRO A 279
PHE A 397
LYS A 277
 None
P1L  A 371 ( 4.6A)
None
 1.06A 3bjwG-5emwA:
undetectable		 3bjwG-5emwA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fyg CYTOCHROME P450

(Marinobacter
hydrocarbonoclasticus) 		PF00067
(p450) 		3 PRO A 153
PHE A 148
LYS A 155
 None
HEM  A1475 (-4.8A)
None
 1.28A 3bjwG-5fygA:
undetectable		 3bjwG-5fygA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h5z MHC CLASS I ANTIGEN

(Ctenopharyngodon
idella) 		no annotation 3 PRO A 191
PHE A 275
LYS A 189
 None
 1.07A 3bjwG-5h5zA:
undetectable		 3bjwG-5h5zA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hd9 ENCAPSIDATION
PROTEIN

(Bacillus virus
phi29) 		PF05894
(Podovirus_Gp16) 		3 PRO A   9
PHE A   6
LYS A  30
 None
 1.26A 3bjwG-5hd9A:
undetectable		 3bjwG-5hd9A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j1t TORSIN-1A

(Homo sapiens) 		PF06309
(Torsin) 		3 PRO A  92
PHE A 203
LYS A  94
 None
 1.27A 3bjwG-5j1tA:
undetectable		 3bjwG-5j1tA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jk7 URACIL-DNA
GLYCOSYLASE

(Homo sapiens) 		PF03167
(UDG) 		3 PRO D 187
PHE D 284
LYS D 302
 None
 0.97A 3bjwG-5jk7D:
undetectable		 3bjwG-5jk7D:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k8s CAMP-DEPENDENT
PROTEIN KINASE
REGULATORY SUBUNIT

(Plasmodium
falciparum) 		PF00027
(cNMP_binding) 		3 PRO A 412
PHE A 349
LYS A 407
 None
 1.21A 3bjwG-5k8sA:
undetectable		 3bjwG-5k8sA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m28 MALE1

(Lactobacillus
casei) 		PF13416
(SBP_bac_8) 		3 PRO A 347
PHE A 121
LYS A 345
 None
 1.28A 3bjwG-5m28A:
undetectable		 3bjwG-5m28A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mq6 PYRIDINE
NUCLEOTIDE-DISULFIDE
OXIDOREDUCTASE-LIKE
PROTEIN

(Thermothelomyces
thermophila) 		PF07992
(Pyr_redox_2) 		3 PRO A 376
PHE A 581
LYS A 585
 None
 1.24A 3bjwG-5mq6A:
1.6		 3bjwG-5mq6A:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5msw THIOESTER REDUCTASE
DOMAIN-CONTAINING
PROTEIN

(Segniliparus
rugosus) 		PF00501
(AMP-binding)
PF00550
(PP-binding) 		3 PRO A 352
PHE A 356
LYS A 354
 None
 1.14A 3bjwG-5mswA:
undetectable		 3bjwG-5mswA:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mv9 UNCONVENTIONAL
MYOSIN-VIIA

(Homo sapiens) 		PF00373
(FERM_M)
PF00784
(MyTH4) 		3 PRO A1846
PHE A1800
LYS A1810
 None
 1.11A 3bjwG-5mv9A:
undetectable		 3bjwG-5mv9A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sv6 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 3

(Methylophaga
aminisulfidivorans) 		PF00497
(SBP_bac_3) 		3 PRO A 123
PHE A 120
LYS A 221
 None
 1.28A 3bjwG-5sv6A:
undetectable		 3bjwG-5sv6A:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		3 PRO A 709
PHE A 650
LYS A 711
 None
 1.21A 3bjwG-5tf0A:
undetectable		 3bjwG-5tf0A:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v8k P800 REACTION CENTER
CORE PROTEIN

(Heliobacterium
modesticaldum) 		PF00223
(PsaA_PsaB) 		3 PRO A  10
PHE A  15
LYS A  19
 GBF  A1004 (-3.8A)
GBF  A1021 (-3.1A)
None
 1.27A 3bjwG-5v8kA:
2.0		 3bjwG-5v8kA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxo PERIPLASMIC
BETA-GLUCOSIDASE

(Bacteroides
thetaiotaomicron) 		no annotation 3 PRO A 707
PHE A 648
LYS A 709
 None
 1.25A 3bjwG-5xxoA:
undetectable		 3bjwG-5xxoA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi 40S RIBOSOMAL
PROTEIN S16,
PUTATIVE

(Trichomonas
vaginalis) 		PF00380
(Ribosomal_S9) 		3 PRO Q 123
PHE Q 126
LYS Q 124
 C  21412 ( 4.3A)
None
A  21411 ( 2.8A)
 1.23A 3bjwG-5xyiQ:
undetectable		 3bjwG-5xyiQ:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yfb DIPEPTIDYL PEPTIDASE
3

(Armillaria
tabescens) 		no annotation 3 PRO A 553
PHE A 550
LYS A 557
 None
 1.13A 3bjwG-5yfbA:
undetectable		 3bjwG-5yfbA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yq5 OSTEOMODULIN

(Homo sapiens) 		no annotation 3 PRO A 161
PHE A 111
LYS A 139
 None
 0.53A 3bjwG-5yq5A:
undetectable		 3bjwG-5yq5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE

(Acinetobacter
baumannii) 		no annotation 3 PRO A 197
PHE A 188
LYS A 192
 None
 1.26A 3bjwG-6bngA:
undetectable		 3bjwG-6bngA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6brk DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1

(Mus musculus) 		no annotation 3 PRO A 318
PHE A 299
LYS A 320
 None
 1.27A 3bjwG-6brkA:
undetectable		 3bjwG-6brkA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cip PYRUVATE-FERREDOXIN
OXIDOREDUCTASE

(Moorella
thermoacetica) 		no annotation 3 PRO A 615
PHE A 537
LYS A 613
 None
 1.25A 3bjwG-6cipA:
undetectable		 3bjwG-6cipA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1

(Danio rerio) 		no annotation 3 PRO A 449
PHE A 455
LYS A 451
 None
 1.26A 3bjwG-6d14A:
undetectable		 3bjwG-6d14A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
3, MITOCHONDRIAL

(Mus musculus) 		no annotation 3 PRO C 167
PHE C 162
LYS C 164
 None
 1.10A 3bjwG-6g2jC:
undetectable		 3bjwG-6g2jC:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gsa -

(-) 		no annotation 3 PRO E 322
PHE E 228
LYS E 233
 None
 1.26A 3bjwG-6gsaE:
undetectable		 3bjwG-6gsaE:
undetectable