SIMILAR PATTERNS OF AMINO ACIDS FOR 3BJW_F_SVRF509

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1adq IGM-LAMBDA RF-AN FAB
(HEAVY CHAIN)

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 VAL H  37
VAL H  48
THR H  95
ARG H  38
 None
 1.20A 3bjwC-1adqH:
0.0		 3bjwC-1adqH:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e0t PYRUVATE KINASE

(Escherichia
coli) 		PF00224
(PK)
PF02887
(PK_C) 		4 VAL A   7
VAL A  30
THR A 306
THR A   9
 None
 1.23A 3bjwC-1e0tA:
0.0		 3bjwC-1e0tA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fux HYPOTHETICAL 19.5
KDA PROTEIN IN
EMRE-RUS INTERGENIC
REGION

(Escherichia
coli) 		PF01161
(PBP) 		4 VAL A  67
VAL A  93
THR A 127
THR A  65
 None
 1.05A 3bjwC-1fuxA:
0.0		 3bjwC-1fuxA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hjo PROTEIN (HEAT-SHOCK
70KD PROTEIN)

(Homo sapiens) 		PF00012
(HSP70) 		4 VAL A 238
THR A 295
THR A 265
ARG A 264
 None
 1.18A 3bjwC-1hjoA:
0.0		 3bjwC-1hjoA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1id0 PHOQ HISTIDINE
KINASE

(Escherichia
coli) 		PF02518
(HATPase_c) 		4 VAL A 413
VAL A 412
THR A 348
ARG A 471
 None
 1.08A 3bjwC-1id0A:
0.3		 3bjwC-1id0A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m0u GST2 GENE PRODUCT

(Drosophila
melanogaster) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 VAL A 227
VAL A 228
THR A 196
ARG A 225
 None
 1.07A 3bjwC-1m0uA:
1.4		 3bjwC-1m0uA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1my6 IRON (III)
SUPEROXIDE DISMUTASE

(Thermosynechococcus
elongatus) 		PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C) 		4 VAL A 132
VAL A 155
THR A 143
THR A 137
 None
 1.14A 3bjwC-1my6A:
0.3		 3bjwC-1my6A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n8p CYSTATHIONINE
GAMMA-LYASE

(Saccharomyces
cerevisiae) 		PF01053
(Cys_Met_Meta_PP) 		4 VAL A 198
VAL A 197
THR A  85
THR A 180
 None
None
None
PLP  A 400 ( 4.1A)
 1.06A 3bjwC-1n8pA:
0.0		 3bjwC-1n8pA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nqz COA PYROPHOSPHATASE
(MUTT/NUDIX FAMILY
PROTEIN)

(Deinococcus
radiodurans) 		PF00293
(NUDIX) 		4 VAL A  50
THR A 181
THR A 143
ARG A  49
 None
 1.22A 3bjwC-1nqzA:
undetectable		 3bjwC-1nqzA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rr9 ATP-DEPENDENT
PROTEASE LA

(Escherichia
coli) 		PF05362
(Lon_C) 		4 VAL A 645
VAL A 644
THR A 615
ARG A 648
 None
 1.07A 3bjwC-1rr9A:
undetectable		 3bjwC-1rr9A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wql IRON-SULFUR PROTEIN
LARGE SUBUNIT OF
CUMENE DIOXYGENASE

(Pseudomonas
fluorescens) 		PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A) 		4 VAL A  86
VAL A  87
THR A 168
THR A  76
 None
 1.14A 3bjwC-1wqlA:
undetectable		 3bjwC-1wqlA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xp4 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE

(Streptococcus
pneumoniae) 		PF00768
(Peptidase_S11)
PF07943
(PBP5_C) 		4 VAL A 251
VAL A 264
THR A  58
THR A 253
 None
 1.15A 3bjwC-1xp4A:
undetectable		 3bjwC-1xp4A:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y9g EXO-INULINASE

(Aspergillus
awamori) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 VAL A 203
VAL A 204
THR A 129
THR A 217
 None
 1.10A 3bjwC-1y9gA:
undetectable		 3bjwC-1y9gA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ydo HMG-COA LYASE

(Bacillus
subtilis) 		PF00682
(HMGL-like) 		4 VAL A  12
THR A  40
THR A  48
ARG A  15
 None
 0.99A 3bjwC-1ydoA:
undetectable		 3bjwC-1ydoA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ygp YEAST GLYCOGEN
PHOSPHORYLASE

(Saccharomyces
cerevisiae) 		PF00343
(Phosphorylase) 		4 VAL A 221
THR A 276
THR A 201
ARG A 220
 None
 1.12A 3bjwC-1ygpA:
undetectable		 3bjwC-1ygpA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ciy CHLOROPEROXIDASE

(Leptoxyphium
fumago) 		PF01328
(Peroxidase_2) 		4 VAL A 141
VAL A 142
THR A 250
THR A 137
 MAN  A 751 ( 4.1A)
None
MAN  A 750 (-2.0A)
None
 1.00A 3bjwC-2ciyA:
undetectable		 3bjwC-2ciyA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ddw PYRIDOXINE KINASE

(Escherichia
coli) 		PF08543
(Phos_pyr_kin) 		4 VAL A 192
VAL A 193
THR A 167
THR A 212
 None
 1.22A 3bjwC-2ddwA:
2.4		 3bjwC-2ddwA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gqw FERREDOXIN REDUCTASE

(Pseudomonas sp.
KKS102) 		PF07992
(Pyr_redox_2)
PF14759
(Reductase_C) 		4 VAL A 106
VAL A  12
THR A 275
THR A 104
 None
 1.11A 3bjwC-2gqwA:
undetectable		 3bjwC-2gqwA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE

(Mycobacterium
tuberculosis) 		PF13399
(LytR_C) 		4 VAL A  39
VAL A  66
THR A  77
THR A  64
 None
 1.19A 3bjwC-2m5yA:
undetectable		 3bjwC-2m5yA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nq5 5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE

(Streptococcus
mutans) 		PF01717
(Meth_synt_2)
PF08267
(Meth_synt_1) 		4 VAL A 693
VAL A 694
THR A 417
THR A 689
 None
 1.14A 3bjwC-2nq5A:
undetectable		 3bjwC-2nq5A:
9.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		4 VAL A   2
VAL A   3
THR A  23
THR A  70
 None
 0.76A 3bjwC-2qheA:
22.8		 3bjwC-2qheA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qr3 TWO-COMPONENT SYSTEM
RESPONSE REGULATOR

(Bacteroides
fragilis) 		PF00072
(Response_reg) 		4 VAL A  48
VAL A  49
THR A 117
THR A   3
 None
 1.18A 3bjwC-2qr3A:
undetectable		 3bjwC-2qr3A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qvx 4-CHLOROBENZOATE COA
LIGASE

(Alcaligenes sp.
AL3007) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 VAL X 209
VAL X 208
THR X 251
ARG X 181
 3BZ  X 505 (-4.9A)
None
None
None
 1.13A 3bjwC-2qvxX:
undetectable		 3bjwC-2qvxX:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wpm COAGULATION FACTOR
IXA HEAVY CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		4 VAL S  65
VAL S  32
THR S  79
THR S  64
 None
 1.13A 3bjwC-2wpmS:
undetectable		 3bjwC-2wpmS:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yz2 PUTATIVE ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0222

(Thermotoga
maritima) 		PF00005
(ABC_tran) 		4 VAL A 208
VAL A 209
THR A 221
ARG A 207
 None
 1.15A 3bjwC-2yz2A:
undetectable		 3bjwC-2yz2A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbc 83AA LONG
HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR ASNC

(Sulfurisphaera
tokodaii) 		PF01037
(AsnC_trans_reg) 		4 VAL A  42
VAL A  31
THR A  69
THR A  29
 None
None
ILE  A  84 (-3.6A)
None
 1.14A 3bjwC-2zbcA:
undetectable		 3bjwC-2zbcA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a1i AMIDASE

(Rhodococcus sp.
N-771) 		PF01425
(Amidase) 		4 VAL A 125
VAL A 124
THR A  83
THR A 100
 None
 1.23A 3bjwC-3a1iA:
undetectable		 3bjwC-3a1iA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE

(Yersinia
pseudotuberculosis) 		PF01041
(DegT_DnrJ_EryC1) 		4 VAL A 394
VAL A 395
THR A 399
ARG A 393
 None
 1.04A 3bjwC-3bb8A:
undetectable		 3bjwC-3bb8A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dto BH2835 PROTEIN

(Bacillus
halodurans) 		PF01966
(HD) 		4 VAL A 118
VAL A 117
THR A  99
THR A  34
 None
 0.81A 3bjwC-3dtoA:
undetectable		 3bjwC-3dtoA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eqq BENZENE
1,2-DIOXYGENASE
SUBUNIT ALPHA

(Pseudomonas
putida) 		PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A) 		4 VAL A  81
VAL A  82
THR A 156
THR A  71
 None
 1.09A 3bjwC-3eqqA:
undetectable		 3bjwC-3eqqA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gec PERIOD CIRCADIAN
PROTEIN

(Drosophila
melanogaster) 		PF00989
(PAS)
PF14598
(PAS_11) 		4 VAL A 489
VAL A 490
THR A 439
ARG A 394
 None
 1.02A 3bjwC-3gecA:
undetectable		 3bjwC-3gecA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gec PERIOD CIRCADIAN
PROTEIN

(Drosophila
melanogaster) 		PF00989
(PAS)
PF14598
(PAS_11) 		4 VAL A 489
VAL A 490
THR A 439
THR A 396
 None
 1.03A 3bjwC-3gecA:
undetectable		 3bjwC-3gecA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3glg DNA POLYMERASE III
SUBUNIT DELTA'

(Escherichia
coli) 		PF09115
(DNApol3-delta_C)
PF13177
(DNA_pol3_delta2) 		4 VAL E 112
VAL E 111
THR E 131
THR E  78
 None
 1.17A 3bjwC-3glgE:
1.1		 3bjwC-3glgE:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrd NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT

(Eubacterium
barkeri) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 VAL A 204
VAL A 192
THR A 234
THR A 202
 None
 1.09A 3bjwC-3hrdA:
undetectable		 3bjwC-3hrdA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hs0 COBRA VENOM FACTOR

(Naja kaouthia) 		PF01835
(A2M_N)
PF07703
(A2M_N_2) 		4 VAL A 391
VAL A 358
THR A 405
ARG A 392
 None
 1.20A 3bjwC-3hs0A:
undetectable		 3bjwC-3hs0A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT

(Hahella
chejuensis) 		PF13407
(Peripla_BP_4) 		4 VAL A 277
VAL A 278
THR A 231
ARG A 310
 None
 1.07A 3bjwC-3ksmA:
0.3		 3bjwC-3ksmA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kya PUTATIVE PHOSPHATASE

(Bacteroides
thetaiotaomicron) 		PF01833
(TIG) 		4 VAL A 434
VAL A 428
THR A 389
THR A 436
 None
 1.23A 3bjwC-3kyaA:
undetectable		 3bjwC-3kyaA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ldr FRUCTOSYLTRANSFERASE

(Aspergillus
japonicus) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 VAL A 594
VAL A 595
THR A 537
THR A 509
 None
 1.20A 3bjwC-3ldrA:
undetectable		 3bjwC-3ldrA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m66 MTERF
DOMAIN-CONTAINING
PROTEIN 1,
MITOCHONDRIAL

(Homo sapiens) 		PF02536
(mTERF) 		4 VAL A 280
VAL A 281
THR A 288
THR A 276
 None
 0.96A 3bjwC-3m66A:
undetectable		 3bjwC-3m66A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mcz O-METHYLTRANSFERASE

(Burkholderia
thailandensis) 		PF00891
(Methyltransf_2)
PF16864
(Dimerisation2) 		4 VAL A 168
VAL A 167
THR A 189
ARG A 333
 None
 0.88A 3bjwC-3mczA:
undetectable		 3bjwC-3mczA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n0w ABC BRANCHED CHAIN
AMINO ACID FAMILY
TRANSPORTER,
PERIPLASMIC LIGAND
BINDING PROTEIN

(Paraburkholderia
xenovorans) 		PF13458
(Peripla_BP_6) 		4 VAL A 341
THR A 123
THR A 284
ARG A 283
 None
 1.17A 3bjwC-3n0wA:
undetectable		 3bjwC-3n0wA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o80 HEXOKINASE

(Kluyveromyces
lactis) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		4 VAL A  70
VAL A  71
THR A 470
ARG A 473
 None
 1.20A 3bjwC-3o80A:
undetectable		 3bjwC-3o80A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p0c NISCHARIN

(Homo sapiens) 		PF00787
(PX) 		4 VAL A  21
VAL A  22
THR A  31
ARG A  20
 None
 1.09A 3bjwC-3p0cA:
undetectable		 3bjwC-3p0cA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pe8 ENOYL-COA HYDRATASE

(Mycolicibacterium
smegmatis) 		PF00378
(ECH_1) 		4 VAL A  15
VAL A  50
THR A  17
ARG A  16
 None
 1.22A 3bjwC-3pe8A:
undetectable		 3bjwC-3pe8A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qfh EPIDERMIN LEADER
PEPTIDE PROCESSING
SERINE PROTEASE EPIP

(Staphylococcus
aureus) 		PF00082
(Peptidase_S8) 		4 VAL A 215
VAL A 162
THR A 141
ARG A 214
 None
 1.23A 3bjwC-3qfhA:
undetectable		 3bjwC-3qfhA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qyr ECHA16_2

(Mycobacterium
avium) 		PF00378
(ECH_1) 		4 VAL A  14
VAL A  49
THR A  16
ARG A  15
 None
 1.20A 3bjwC-3qyrA:
undetectable		 3bjwC-3qyrA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qz1 STEROID
21-HYDROXYLASE

(Bos taurus) 		PF00067
(p450) 		4 VAL A 440
VAL A 439
THR A 295
ARG A 443
 None
None
HEM  A 500 (-3.3A)
None
 0.78A 3bjwC-3qz1A:
undetectable		 3bjwC-3qz1A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rd5 MYPAA.01249.C

(Mycobacterium
avium) 		PF00106
(adh_short) 		4 VAL A  17
VAL A  18
THR A 233
THR A  40
 None
 1.15A 3bjwC-3rd5A:
undetectable		 3bjwC-3rd5A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3riq TAILSPIKE PROTEIN

(Salmonella
virus 9NA) 		PF09251
(PhageP22-tail) 		4 VAL A 378
VAL A 350
THR A 401
THR A 380
 None
 1.03A 3bjwC-3riqA:
undetectable		 3bjwC-3riqA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rq1 AMINOTRANSFERASE
CLASS I AND II

(Veillonella
parvula) 		PF00155
(Aminotran_1_2) 		4 VAL A 126
VAL A 179
THR A 143
THR A 128
 None
 1.13A 3bjwC-3rq1A:
undetectable		 3bjwC-3rq1A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rty PERIOD CIRCADIAN
PROTEIN

(Drosophila
melanogaster) 		PF00989
(PAS)
PF14598
(PAS_11) 		4 VAL A 489
VAL A 490
THR A 439
THR A 396
 None
 0.93A 3bjwC-3rtyA:
undetectable		 3bjwC-3rtyA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t3o METAL DEPENDENT
HYDROLASE

(Thermus
thermophilus) 		PF07521
(RMMBL)
PF12706
(Lactamase_B_2) 		4 VAL A 159
VAL A 158
THR A 389
THR A 142
 None
 1.23A 3bjwC-3t3oA:
undetectable		 3bjwC-3t3oA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B

(Bacillus
subtilis) 		PF12705
(PDDEXK_1) 		4 VAL B 482
THR B 512
THR B 477
ARG B 478
 None
 1.12A 3bjwC-3u44B:
undetectable		 3bjwC-3u44B:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1

(Rattus
norvegicus) 		no annotation 4 VAL A  64
VAL A  65
THR A  22
ARG A  20
 None
 1.12A 3bjwC-3u9gA:
undetectable		 3bjwC-3u9gA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ug7 ARSENICAL
PUMP-DRIVING ATPASE

(Methanocaldococcus
jannaschii) 		PF02374
(ArsA_ATPase) 		4 VAL A  91
VAL A  58
THR A  40
THR A  81
 None
None
MG  A 403 ( 3.2A)
None
 1.18A 3bjwC-3ug7A:
undetectable		 3bjwC-3ug7A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ac3 BIFUNCTIONAL PROTEIN
GLMU

(Streptococcus
pneumoniae) 		PF00132
(Hexapep)
PF00483
(NTP_transferase)
PF14602
(Hexapep_2) 		4 VAL A 149
VAL A 142
THR A 216
ARG A 151
 None
 1.21A 3bjwC-4ac3A:
undetectable		 3bjwC-4ac3A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ah6 ASPARTATE--TRNA
LIGASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
PF02938
(GAD) 		4 VAL A 469
VAL A 468
THR A 474
THR A 465
 None
 1.18A 3bjwC-4ah6A:
undetectable		 3bjwC-4ah6A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b9w TUDOR
DOMAIN-CONTAINING
PROTEIN 1

(Mus musculus) 		PF00567
(TUDOR) 		4 VAL A 855
VAL A 856
THR A 709
ARG A 854
 None
 1.13A 3bjwC-4b9wA:
undetectable		 3bjwC-4b9wA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b9x TUDOR
DOMAIN-CONTAINING
PROTEIN 1

(Mus musculus) 		PF00567
(TUDOR) 		4 VAL A 855
VAL A 856
THR A 709
ARG A 854
 None
 1.08A 3bjwC-4b9xA:
undetectable		 3bjwC-4b9xA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bju N-ACETYLGLUCOSAMINE-
PHOSPHATE MUTASE

(Aspergillus
fumigatus) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I) 		4 VAL A 335
VAL A 357
THR A 388
THR A 337
 None
 1.09A 3bjwC-4bjuA:
undetectable		 3bjwC-4bjuA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cgy DNA TOPOISOMERASE
3-ALPHA

(Homo sapiens) 		PF01131
(Topoisom_bac)
PF01751
(Toprim) 		4 VAL A 252
VAL A 253
THR A 554
THR A 248
 None
 1.04A 3bjwC-4cgyA:
undetectable		 3bjwC-4cgyA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cp6 CHOLINE BINDING
PROTEIN PCPA

(Streptococcus
pneumoniae) 		PF13306
(LRR_5) 		4 VAL A  53
VAL A  40
THR A  99
THR A  38
 None
 1.10A 3bjwC-4cp6A:
undetectable		 3bjwC-4cp6A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0s 5-METHYLTHIOADENOSIN
E/S-ADENOSYLHOMOCYST
EINE DEAMINASE

(Chromobacterium
violaceum) 		PF01979
(Amidohydro_1) 		4 VAL A 205
VAL A 206
THR A 188
THR A 201
 None
 0.97A 3bjwC-4f0sA:
undetectable		 3bjwC-4f0sA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g2r ACCD6,
CARBOXYLTRANSFERASE
BETA-SUBUNIT OF
ACYL-COA CARBOXYLASE

(Mycobacterium
tuberculosis) 		PF01039
(Carboxyl_trans) 		4 VAL A 114
VAL A 111
THR A 146
THR A  74
 None
 1.22A 3bjwC-4g2rA:
undetectable		 3bjwC-4g2rA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h16 SHORT CHAIN ALCOHOL
DEHYDROGENASE-RELATE
D DEHYDROGENASE

(Sinorhizobium
meliloti) 		PF13561
(adh_short_C2) 		4 VAL A  66
THR A  58
THR A  70
ARG A  73
 None
 1.14A 3bjwC-4h16A:
undetectable		 3bjwC-4h16A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iyo CYSTATHIONINE
GAMMA-LYASE-LIKE
PROTEIN, LYS201A
MODIFIED

(Xanthomonas
oryzae) 		PF01053
(Cys_Met_Meta_PP) 		4 VAL B 205
VAL B 204
THR B  94
THR B 187
 None
None
None
LLP  B 210 ( 3.8A)
 1.17A 3bjwC-4iyoB:
undetectable		 3bjwC-4iyoB:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4li3 CYSTEINE SYNTHASE

(Haemophilus
influenzae) 		PF00291
(PALP) 		4 VAL X 172
VAL X 173
THR X 157
THR X 198
 None
 1.15A 3bjwC-4li3X:
undetectable		 3bjwC-4li3X:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nky STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE

(Homo sapiens) 		PF00067
(p450) 		4 VAL A 310
VAL A 311
THR A 356
THR A 306
 None
None
None
HEM  A 600 ( 3.2A)
 1.16A 3bjwC-4nkyA:
undetectable		 3bjwC-4nkyA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ptx GLYCOSIDE HYDROLASE
FAMILY 1

(Halothermothrix
orenii) 		PF00232
(Glyco_hydro_1) 		4 VAL A 301
VAL A 315
THR A 224
ARG A 302
 None
 1.22A 3bjwC-4ptxA:
undetectable		 3bjwC-4ptxA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qdk MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE

(Synechocystis
sp. PCC 6803) 		PF07109
(Mg-por_mtran_C) 		4 VAL A  51
VAL A  52
THR A 130
THR A  47
 None
 1.03A 3bjwC-4qdkA:
undetectable		 3bjwC-4qdkA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r1p L-ARABINOSE
ISOMERASE

(Geobacillus
kaustophilus) 		PF02610
(Arabinose_Isome)
PF11762
(Arabinose_Iso_C) 		4 VAL A 321
THR A 274
THR A 167
ARG A 166
 None
 1.23A 3bjwC-4r1pA:
undetectable		 3bjwC-4r1pA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r27 GLYCOSIDE HYDROLASE

(Microbacterium
sp. Gsoil167) 		PF00232
(Glyco_hydro_1) 		4 VAL A 122
VAL A 166
THR A  81
THR A 124
 None
 1.02A 3bjwC-4r27A:
undetectable		 3bjwC-4r27A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus T4;
Rattus
norvegicus) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 VAL A  67
VAL A  68
THR A 126
THR A  63
 None
 1.01A 3bjwC-4u16A:
1.0		 3bjwC-4u16A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wqm TOLUENE-4-MONOOXYGEN
ASE ELECTRON
TRANSFER COMPONENT

(Pseudomonas
mendocina) 		PF00111
(Fer2)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		4 VAL A 107
VAL A 108
THR A 182
ARG A 106
 None
 1.17A 3bjwC-4wqmA:
undetectable		 3bjwC-4wqmA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zfz MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS I

(Macaca mulatta) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 VAL A  24
VAL A  25
THR A  64
THR A  10
 None
 1.18A 3bjwC-4zfzA:
undetectable		 3bjwC-4zfzA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a8r METHYL-COENZYME M
REDUCTASE II SUBUNIT
GAMMA

(Methanothermobacter
marburgensis) 		PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		4 VAL B 201
VAL B 200
THR B 411
THR B 208
 None
 1.11A 3bjwC-5a8rB:
undetectable		 3bjwC-5a8rB:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aca VP1

(Foot-and-mouth
disease virus) 		PF00073
(Rhv) 		4 VAL 1  35
VAL 1  32
THR 1  40
THR 1  30
 None
 1.16A 3bjwC-5aca1:
undetectable		 3bjwC-5aca1:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5awf FES CLUSTER ASSEMBLY
PROTEIN SUFB

(Escherichia
coli) 		PF01458
(UPF0051) 		4 VAL A 269
VAL A 268
THR A 283
ARG A 237
 None
 1.20A 3bjwC-5awfA:
undetectable		 3bjwC-5awfA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bq3 RHAMNOSE ABC
TRANSPORTER,
RHAMNOSE-BINDING
PROTEIN

(Actinomyces
odontolyticus) 		PF13407
(Peripla_BP_4) 		4 VAL A 334
VAL A 335
THR A 135
THR A 327
 None
 1.21A 3bjwC-5bq3A:
undetectable		 3bjwC-5bq3A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cdi CHAPERONIN 60B1

(Chlamydomonas
reinhardtii) 		PF00118
(Cpn60_TCP1) 		4 VAL A 302
VAL A 301
THR A 314
ARG A 303
 None
 1.05A 3bjwC-5cdiA:
0.5		 3bjwC-5cdiA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dll AMINOPEPTIDASE N

(Francisella
tularensis) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		4 VAL A  41
VAL A 105
THR A  28
THR A  39
 NA  A 917 (-4.6A)
NA  A 917 ( 4.1A)
None
None
 0.90A 3bjwC-5dllA:
undetectable		 3bjwC-5dllA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dmh UNCHARACTERIZED
PROTEIN CONSERVED IN
BACTERIA

(Cupriavidus
necator) 		PF07005
(DUF1537)
PF17042
(DUF1357_C) 		4 VAL A 377
VAL A 378
THR A 363
THR A 373
 None
None
None
ADP  A 501 (-3.8A)
 1.19A 3bjwC-5dmhA:
undetectable		 3bjwC-5dmhA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eog PROTEIN MAB-21-LIKE
1

(Homo sapiens) 		PF03281
(Mab-21) 		4 VAL A 167
VAL A 168
THR A 155
THR A  72
 None
 1.15A 3bjwC-5eogA:
undetectable		 3bjwC-5eogA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5far 7,8-DIHYDRONEOPTERIN
ALDOLASE

(Bacillus cereus) 		PF02152
(FolB) 		4 VAL A  64
VAL A  63
THR A  68
ARG A  67
 None
 1.19A 3bjwC-5farA:
undetectable		 3bjwC-5farA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k1s OXIDOREDUCTASE,
ZINC-BINDING
DEHYDROGENASE FAMILY

(Myxococcus
xanthus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 VAL A 261
VAL A 238
THR A 247
ARG A 260
 None
 1.16A 3bjwC-5k1sA:
undetectable		 3bjwC-5k1sA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n29 CTP SYNTHASE

(Trypanosoma
brucei) 		PF00117
(GATase) 		4 VAL A 474
VAL A 494
THR A 562
THR A 522
 None
 1.19A 3bjwC-5n29A:
undetectable		 3bjwC-5n29A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nxn PORIN 1

(Providencia
stuartii) 		no annotation 4 VAL A 101
VAL A 100
THR A 249
THR A 104
 None
 1.17A 3bjwC-5nxnA:
undetectable		 3bjwC-5nxnA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5och -

(-) 		no annotation 4 VAL B 531
VAL B 530
THR B 496
ARG B 539
 None
 1.20A 3bjwC-5ochB:
undetectable		 3bjwC-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5odr METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
A

(Methanothermococcus
thermolithotrophicus) 		PF00374
(NiFeSe_Hases) 		4 VAL F 397
VAL F 396
THR F  57
THR F 399
 NFU  F 501 (-4.4A)
None
None
NFU  F 501 (-3.7A)
 1.19A 3bjwC-5odrF:
undetectable		 3bjwC-5odrF:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5szp PROTOCADHERIN GAMMA
B7

(Mus musculus) 		PF00028
(Cadherin)
PF08266
(Cadherin_2) 		4 VAL A 202
VAL A 203
THR A 177
ARG A 201
 None
 1.20A 3bjwC-5szpA:
undetectable		 3bjwC-5szpA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t5w INTERFERON LAMBDA
RECEPTOR 1

(Homo sapiens) 		PF01108
(Tissue_fac) 		4 VAL B  80
VAL B  37
THR B  11
THR B  82
 None
 1.20A 3bjwC-5t5wB:
undetectable		 3bjwC-5t5wB:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tpk PROTOCADHERIN-15

(Mus musculus) 		no annotation 4 VAL A 805
VAL A 806
THR A 815
THR A 892
 None
 1.23A 3bjwC-5tpkA:
undetectable		 3bjwC-5tpkA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ulu CADHERIN-23

(Mus musculus) 		no annotation 4 VAL A2121
VAL A2122
THR A2050
ARG A2084
 None
 1.17A 3bjwC-5uluA:
undetectable		 3bjwC-5uluA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vqi IMPORTIN SUBUNIT
ALPHA

(Neurospora
crassa) 		no annotation 4 VAL B 161
VAL B 162
THR B 123
THR B 157
 None
 1.22A 3bjwC-5vqiB:
undetectable		 3bjwC-5vqiB:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xpg UNCHARACTERIZED
PROTEIN

(Thermus
thermophilus) 		no annotation 4 VAL A 193
VAL A 262
THR A 201
ARG A 194
 None
 1.20A 3bjwC-5xpgA:
undetectable		 3bjwC-5xpgA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y0s THERMOTOGA MARITIMA
TMCAL

(Thermotoga
maritima) 		no annotation 4 VAL A  66
VAL A  67
THR A  93
THR A 343
 None
 1.23A 3bjwC-5y0sA:
undetectable		 3bjwC-5y0sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c66 CRISPR-ASSOCIATED
PROTEIN, CSE1 FAMILY

(Thermobifida
fusca) 		no annotation 4 VAL A 148
THR A 198
THR A 156
ARG A 155
 None
 1.13A 3bjwC-6c66A:
undetectable		 3bjwC-6c66A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ejm SINGLE CHAIN FV
FRAGMENT

(Mus musculus) 		no annotation 4 VAL H  75
VAL H  86
THR H 138
ARG H  76
 None
 1.21A 3bjwC-6ejmH:
undetectable		 3bjwC-6ejmH:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculosis) 		no annotation 4 VAL A 166
THR A 179
THR A 306
ARG A 307
 VAL  A 166 ( 0.6A)
THR  A 179 ( 0.8A)
THR  A 306 ( 0.8A)
ARG  A 307 ( 0.6A)
 1.11A 3bjwC-6gefA:
undetectable		 3bjwC-6gefA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gnf -

(-) 		no annotation 4 VAL A   7
VAL A  41
THR A 176
THR A   9
 None
 1.16A 3bjwC-6gnfA:
1.4		 3bjwC-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cij PROTEIN (HALOALKANE
DEHALOGENASE)

(Xanthobacter
autotrophicus) 		PF00561
(Abhydrolase_1) 		4 TYR A  63
PRO A 134
PHE A 243
TRP A 244
 None
 1.48A 3bjwD-1cijA:
undetectable		 3bjwD-1cijA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dtx ALPHA-DENDROTOXIN

(Dendroaspis
angusticeps) 		PF00014
(Kunitz_BPTI) 		4 LYS A   2
TYR A  25
ASN A  26
LYS A  30
 PCA  A   1 ( 2.9A)
None
None
None
 1.42A 3bjwD-1dtxA:
undetectable		 3bjwD-1dtxA:
17.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gmz PHOSPHOLIPASE A2

(Bothrops
pirajai) 		PF00068
(Phospholip_A2_1) 		4 LYS A  15
TYR A 103
ASN A 104
LYS A 105
 None
 0.96A 3bjwD-1gmzA:
19.7		 3bjwD-1gmzA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1god PROTEIN
(PHOSPHOLIPASE A2)

(Cerrophidion
godmani) 		PF00068
(Phospholip_A2_1) 		4 LYS A  16
TYR A 113
ASN A 114
PRO A 121
 None
 0.99A 3bjwD-1godA:
19.8		 3bjwD-1godA:
56.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hle HORSE LEUKOCYTE
ELASTASE INHIBITOR

(Equus caballus) 		PF00079
(Serpin) 		4 TYR A 222
LYS A 224
LYS A 225
PRO A 228
 None
 1.29A 3bjwD-1hleA:
undetectable		 3bjwD-1hleA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j5s URONATE ISOMERASE

(Thermotoga
maritima) 		PF02614
(UxaC) 		4 TYR A 268
PRO A 154
PHE A 222
TRP A 177
 None
 1.42A 3bjwD-1j5sA:
undetectable		 3bjwD-1j5sA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1np7 DNA PHOTOLYASE

(Synechocystis
sp. PCC 6803) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		4 TYR A 236
PRO A 254
PHE A  62
TRP A 255
 FAD  A 500 (-4.5A)
None
None
None
 1.36A 3bjwD-1np7A:
undetectable		 3bjwD-1np7A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qvb BETA-GLYCOSIDASE

(Thermosphaera
aggregans) 		PF00232
(Glyco_hydro_1) 		4 LYS A 283
ASN A 376
LYS A 372
PRO A 417
 None
 1.47A 3bjwD-1qvbA:
0.0		 3bjwD-1qvbA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qvb BETA-GLYCOSIDASE

(Thermosphaera
aggregans) 		PF00232
(Glyco_hydro_1) 		4 TYR A 150
ASN A 207
PHE A 440
TRP A 424
 None
 1.46A 3bjwD-1qvbA:
0.0		 3bjwD-1qvbA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s5j DNA POLYMERASE I

(Sulfolobus
solfataricus) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		4 TYR A 460
ASN A 160
LYS A 157
PRO A 138
 None
None
SO4  A 883 (-4.5A)
SO4  A 883 (-4.4A)
 1.39A 3bjwD-1s5jA:
undetectable		 3bjwD-1s5jA:
9.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1s8h PHOSPHOLIPASE A2
HOMOLOG

(Agkistrodon
contortrix) 		PF00068
(Phospholip_A2_1) 		4 LYS A  16
TYR A 113
ASN A 114
LYS A 115
 None
 0.92A 3bjwD-1s8hA:
20.3		 3bjwD-1s8hA:
62.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tr1 BETA-GLUCOSIDASE A

(Paenibacillus
polymyxa) 		PF00232
(Glyco_hydro_1) 		4 TYR A 120
ASN A 165
PHE A 414
TRP A 398
 None
None
GOL  A2000 (-3.9A)
GOL  A2000 (-3.2A)
 1.49A 3bjwD-1tr1A:
undetectable		 3bjwD-1tr1A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tz9 MANNONATE
DEHYDRATASE

(Enterococcus
faecalis) 		PF03786
(UxuA) 		4 ASN A 224
LYS A 223
PRO A 211
PHE A 130
 None
 0.85A 3bjwD-1tz9A:
undetectable		 3bjwD-1tz9A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v87 DELTEX PROTEIN 2

(Mus musculus) 		PF00097
(zf-C3HC4) 		4 TYR A  74
ASN A  78
LYS A  79
TRP A 101
 None
 1.25A 3bjwD-1v87A:
undetectable		 3bjwD-1v87A:
19.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1vip PHOSPHOLIPASE A2

(Daboia russelii) 		PF00068
(Phospholip_A2_1) 		4 LYS A  16
TYR A 113
LYS A 115
PRO A 121
 None
 0.86A 3bjwD-1vipA:
20.8		 3bjwD-1vipA:
49.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wzo HPCE

(Thermus
thermophilus) 		PF01557
(FAA_hydrolase) 		4 ASN A 240
LYS A  82
PRO A  40
PHE A  41
 None
 1.48A 3bjwD-1wzoA:
undetectable		 3bjwD-1wzoA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zt5 INSULIN-LIKE GROWTH
FACTOR BINDING
PROTEIN 1

(Homo sapiens) 		PF00086
(Thyroglobulin_1) 		4 TYR A 212
ASN A 235
LYS A 237
PRO A 240
 None
 1.39A 3bjwD-1zt5A:
undetectable		 3bjwD-1zt5A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2asn NITROPHORIN 2

(Rhodnius
prolixus) 		PF02087
(Nitrophorin) 		4 TYR X  58
ASN X  59
LYS X  63
LYS X  62
 None
 1.39A 3bjwD-2asnX:
undetectable		 3bjwD-2asnX:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bx7 DIHYDROOROTATE
DEHYDROGENASE

(Lactococcus
lactis) 		PF01180
(DHO_dh) 		4 ASN A  90
LYS A  88
PRO A  95
PHE A  11
 None
 1.48A 3bjwD-2bx7A:
undetectable		 3bjwD-2bx7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d1g ACID PHOSPHATASE

(Francisella
tularensis) 		PF04185
(Phosphoesterase) 		4 TYR A 353
PRO A 290
PHE A 291
TRP A 252
 None
 1.39A 3bjwD-2d1gA:
undetectable		 3bjwD-2d1gA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN

(Clostridium
acetobutylicum) 		PF01979
(Amidohydro_1) 		4 LYS A 245
LYS A 241
PRO A 205
PHE A 203
 None
None
None
GUN  A 503 (-3.5A)
 1.50A 3bjwD-2i9uA:
undetectable		 3bjwD-2i9uA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j4d CRYPTOCHROME DASH

(Arabidopsis
thaliana) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		4 TYR A 272
PRO A 290
PHE A  97
TRP A 291
 FAD  A1498 (-4.6A)
None
None
None
 1.39A 3bjwD-2j4dA:
undetectable		 3bjwD-2j4dA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE

(Saccharomyces
cerevisiae) 		PF01507
(PAPS_reduct) 		4 LYS A  95
ASN A 202
PRO A  30
TRP A 190
 None
 1.13A 3bjwD-2oq2A:
undetectable		 3bjwD-2oq2A:
16.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		4 LYS A  16
TYR A 113
ASN A 114
PRO A 121
 None
 1.29A 3bjwD-2qheA:
22.8		 3bjwD-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		4 LYS A 116
PRO A 121
PHE A 124
TRP A 125
 None
 0.96A 3bjwD-2qheA:
22.8		 3bjwD-2qheA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qq6 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN

(Rubrobacter
xylanophilus) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 TYR A 269
LYS A 292
PRO A 315
PHE A 337
 None
 1.46A 3bjwD-2qq6A:
undetectable		 3bjwD-2qq6A:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rdy BH0842 PROTEIN

(Bacillus
halodurans) 		PF14498
(Glyco_hyd_65N_2) 		4 TYR A  88
ASN A 423
PRO A 505
TRP A 446
 None
 1.21A 3bjwD-2rdyA:
undetectable		 3bjwD-2rdyA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vxr BOTULINUM NEUROTOXIN
TYPE G

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 LYS A 943
TYR A1142
ASN A1134
PRO A1131
 GOL  A2005 (-4.0A)
None
None
None
 1.47A 3bjwD-2vxrA:
undetectable		 3bjwD-2vxrA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y8d ERYTHROCYTE MEMBRANE
PROTEIN 1

(Plasmodium
falciparum) 		PF05424
(Duffy_binding) 		4 TYR A2411
PRO A2496
PHE A2495
TRP A2473
 None
 1.37A 3bjwD-2y8dA:
undetectable		 3bjwD-2y8dA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus) 		PF03069
(FmdA_AmdA) 		4 LYS A 274
ASN A 113
PRO A 263
TRP A  84
 EDO  A 496 (-2.7A)
None
None
None
 1.49A 3bjwD-3b9tA:
undetectable		 3bjwD-3b9tA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c9f 5'-NUCLEOTIDASE

(Candida
albicans) 		PF00149
(Metallophos) 		4 TYR A 348
ASN A 347
LYS A 396
PRO A 398
 None
 1.43A 3bjwD-3c9fA:
undetectable		 3bjwD-3c9fA:
10.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L

(Vipera
ammodytes) 		PF00068
(Phospholip_A2_1) 		4 LYS A  15
TYR A 103
ASN A 104
LYS A 105
 None
 1.07A 3bjwD-3dihA:
22.0		 3bjwD-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L

(Vipera
ammodytes) 		PF00068
(Phospholip_A2_1) 		4 LYS A  15
TYR A 103
ASN A 104
LYS A 106
 None
 1.20A 3bjwD-3dihA:
22.0		 3bjwD-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L

(Vipera
ammodytes) 		PF00068
(Phospholip_A2_1) 		4 LYS A  15
TYR A 103
LYS A 106
PHE A 113
 None
 1.43A 3bjwD-3dihA:
22.0		 3bjwD-3dihA:
64.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fd2 SITE-SPECIFIC DNA
ENDONUCLEASE I-MSOI

(Monomastix sp.
OKE-1) 		PF00961
(LAGLIDADG_1) 		4 ASN A 109
LYS A 106
LYS A 105
PHE A  48
 None
 1.08A 3bjwD-3fd2A:
undetectable		 3bjwD-3fd2A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fd2 SITE-SPECIFIC DNA
ENDONUCLEASE I-MSOI

(Monomastix sp.
OKE-1) 		PF00961
(LAGLIDADG_1) 		4 ASN A 312
LYS A 309
LYS A 308
PHE A 251
 None
 1.06A 3bjwD-3fd2A:
undetectable		 3bjwD-3fd2A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gkj NIEMANN-PICK C1
PROTEIN

(Homo sapiens) 		PF16414
(NPC1_N) 		4 ASN A 198
LYS A 196
PRO A 207
PHE A 209
 HC3  A 253 ( 3.8A)
None
None
None
 1.39A 3bjwD-3gkjA:
undetectable		 3bjwD-3gkjA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gnr OS03G0212800 PROTEIN

(Oryza sativa) 		PF00232
(Glyco_hydro_1) 		4 TYR A 131
ASN A 177
PHE A 460
TRP A 444
 TYR  A 131 ( 1.3A)
ASN  A 177 (-0.6A)
PHE  A 460 (-1.3A)
TRP  A 444 (-0.5A)
 1.42A 3bjwD-3gnrA:
undetectable		 3bjwD-3gnrA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gq9 PRENECK APPENDAGE
PROTEIN

(Bacillus virus
phi29) 		PF11962
(Peptidase_G2)
PF12708
(Pectate_lyase_3) 		4 ASN A 393
LYS A 394
PRO A 300
PHE A 277
 None
 1.34A 3bjwD-3gq9A:
undetectable		 3bjwD-3gq9A:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3icf SERINE/THREONINE-PRO
TEIN PHOSPHATASE T

(Saccharomyces
cerevisiae) 		PF00149
(Metallophos)
PF08321
(PPP5) 		4 ASN A 317
LYS A 318
PRO A 382
PHE A 388
 None
 1.26A 3bjwD-3icfA:
undetectable		 3bjwD-3icfA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j70 ENVELOPE
GLYCOPROTEIN GP120

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		4 ASN D 392
LYS D 362
PHE D 396
TRP D 400
 None
 1.48A 3bjwD-3j70D:
undetectable		 3bjwD-3j70D:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j9e VP5

(Bluetongue
virus) 		PF00901
(Orbi_VP5) 		4 LYS D   3
ASN D 434
PRO D 370
TRP D 371
 None
 1.31A 3bjwD-3j9eD:
undetectable		 3bjwD-3j9eD:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-PROCESSING
FACTOR 17
PRE-MRNA-SPLICING
FACTOR CWF5

(Schizosaccharomyces
pombe) 		PF01423
(LSM)
PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 ASN g  83
LYS g  82
PRO a  20
PHE a  54
 None
 1.49A 3bjwD-3jb9g:
undetectable		 3bjwD-3jb9g:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jd8 NIEMANN-PICK C1
PROTEIN

(Homo sapiens) 		PF02460
(Patched)
PF12349
(Sterol-sensing)
PF16414
(NPC1_N) 		4 ASN A 198
LYS A 196
PRO A 207
PHE A 209
 CLR  A1325 ( 3.9A)
None
None
None
 1.42A 3bjwD-3jd8A:
undetectable		 3bjwD-3jd8A:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2i ACYL-COENZYME A
THIOESTERASE 4

(Homo sapiens) 		PF04775
(Bile_Hydr_Trans)
PF08840
(BAAT_C) 		4 ASN A 305
LYS A 304
PRO A 310
PHE A 244
 None
 1.38A 3bjwD-3k2iA:
undetectable		 3bjwD-3k2iA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mpp BOTULINUM NEUROTOXIN
TYPE G

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 LYS G 943
TYR G1142
ASN G1134
PRO G1131
 None
 1.49A 3bjwD-3mppG:
undetectable		 3bjwD-3mppG:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p1u SUSD HOMOLOG

(Parabacteroides
distasonis) 		PF12741
(SusD-like) 		4 ASN A 290
LYS A 316
PRO A 319
PHE A 411
 None
 1.33A 3bjwD-3p1uA:
undetectable		 3bjwD-3p1uA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ryk DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE

(Bacillus
anthracis) 		PF00908
(dTDP_sugar_isom) 		4 TYR A  30
ASN A  31
LYS A  32
LYS A  33
 None
 1.15A 3bjwD-3rykA:
undetectable		 3bjwD-3rykA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vas PUTATIVE ADENOSINE
KINASE

(Schistosoma
mansoni) 		PF00294
(PfkB) 		4 TYR A  97
ASN A 100
LYS A  99
PHE A  81
 None
 1.32A 3bjwD-3vasA:
undetectable		 3bjwD-3vasA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vup BETA-1,4-MANNANASE

(Aplysia kurodai) 		PF00150
(Cellulase) 		4 TYR A 102
LYS A  49
LYS A  50
PHE A 308
 None
 1.46A 3bjwD-3vupA:
undetectable		 3bjwD-3vupA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE

(Plasmodium
falciparum) 		PF05424
(Duffy_binding) 		4 TYR A 337
ASN A 339
PRO A 344
PHE A 346
 None
 1.45A 3bjwD-3vuuA:
undetectable		 3bjwD-3vuuA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bfe CELL SURFACE
GLYCOPROTEIN CD200
RECEPTOR 4

(Mus musculus) 		PF07686
(V-set)
PF08205
(C2-set_2) 		4 TYR A  62
ASN A  63
LYS A  67
LYS A  66
 NAG  A 690 (-4.9A)
None
None
None
 1.25A 3bjwD-4bfeA:
undetectable		 3bjwD-4bfeA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ewt PEPTIDASE,
M20/M25/M40 FAMILY

(Staphylococcus
aureus) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 TYR A 293
ASN A 294
PRO A 142
PHE A  31
 None
 1.48A 3bjwD-4ewtA:
undetectable		 3bjwD-4ewtA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fbq DNA REPAIR AND
TELOMERE MAINTENANCE
PROTEIN NBS1,DNA
REPAIR PROTEIN RAD32
CHIMERIC PROTEIN

(Schizosaccharomyces
pombe) 		PF00149
(Metallophos)
PF04152
(Mre11_DNA_bind) 		4 TYR A1260
ASN A1261
LYS A1265
PHE A1205
 None
 1.20A 3bjwD-4fbqA:
undetectable		 3bjwD-4fbqA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g4s PROTEASOME ASSEMBLY
CHAPERONE 2

(Saccharomyces
cerevisiae) 		PF09754
(PAC2) 		4 TYR P  74
ASN P  75
LYS P  76
LYS P  77
 None
 1.20A 3bjwD-4g4sP:
undetectable		 3bjwD-4g4sP:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gf0 GLUTATHIONE
S-TRANSFERASE

(Sulfitobacter
sp. NAS-14.1) 		PF02798
(GST_N)
PF13410
(GST_C_2) 		4 LYS A 112
ASN A 170
PRO A 163
PHE A 158
 None
 1.33A 3bjwD-4gf0A:
undetectable		 3bjwD-4gf0A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hea NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 12

(Thermus
thermophilus) 		PF00361
(Proton_antipo_M)
PF00662
(Proton_antipo_N) 		4 TYR L 297
LYS L 293
LYS L 292
PHE L 425
 None
 1.41A 3bjwD-4heaL:
undetectable		 3bjwD-4heaL:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hvf GREEN FLUORESCENT
PROTEIN BLFP-Y6

(Branchiostoma
lanceolatum) 		PF01353
(GFP) 		4 ASN A 150
LYS A 180
PRO A  74
PHE A  67
 None
 1.45A 3bjwD-4hvfA:
undetectable		 3bjwD-4hvfA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hw8 BACTERIAL
EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, PUTATIVE

(Staphylococcus
aureus) 		PF13416
(SBP_bac_8) 		4 TYR A 158
ASN A 159
LYS A 160
LYS A 161
 None
 1.29A 3bjwD-4hw8A:
undetectable		 3bjwD-4hw8A:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iss ALLOPHANATE
HYDROLASE

(Kluyveromyces
lactis) 		PF01425
(Amidase) 		4 TYR A 148
ASN A 381
PRO A 272
TRP A 265
 None
 1.42A 3bjwD-4issA:
undetectable		 3bjwD-4issA:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j3b M1 FAMILY
AMINOPEPTIDASE

(Plasmodium
falciparum) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		4 TYR A1077
ASN A1073
PRO A 459
PHE A 457
 None
None
ARG  A1101 (-3.9A)
None
 1.21A 3bjwD-4j3bA:
undetectable		 3bjwD-4j3bA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j3o OUTER MEMBRANE USHER
PROTEIN FIMD

(Escherichia
coli) 		PF00577
(Usher)
PF13953
(PapC_C)
PF13954
(PapC_N) 		4 TYR D 418
ASN D 419
LYS D 420
PRO D 254
 None
 1.41A 3bjwD-4j3oD:
undetectable		 3bjwD-4j3oD:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jge RED FLUORESCENT
PROTEIN BLFP-R5

(Branchiostoma
lanceolatum) 		PF01353
(GFP) 		4 ASN A 150
LYS A 180
PRO A  74
PHE A  67
 None
 1.41A 3bjwD-4jgeA:
undetectable		 3bjwD-4jgeA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ptx GLYCOSIDE HYDROLASE
FAMILY 1

(Halothermothrix
orenii) 		PF00232
(Glyco_hydro_1) 		4 TYR A 120
ASN A 165
PHE A 417
TRP A 401
 None
BGC  A 501 (-3.3A)
BGC  A 501 (-3.8A)
BGC  A 501 (-3.6A)
 1.43A 3bjwD-4ptxA:
undetectable		 3bjwD-4ptxA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qlz SJCHGC07024 PROTEIN

(Schistosoma
japonicum) 		PF00719
(Pyrophosphatase) 		4 LYS A 152
TYR A  91
PRO A  65
PHE A  16
 CO  A 404 ( 3.2A)
PO4  A 405 (-4.6A)
None
None
 1.27A 3bjwD-4qlzA:
undetectable		 3bjwD-4qlzA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rm9 EZRIN

(Homo sapiens) 		PF00373
(FERM_M)
PF00769
(ERM)
PF09379
(FERM_N)
PF09380
(FERM_C) 		4 TYR A 270
ASN A 210
LYS A 211
LYS A 212
 None
 1.46A 3bjwD-4rm9A:
undetectable		 3bjwD-4rm9A:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ry9 PERIPLASMIC BINDING
PROTEIN/LACI
TRANSCRIPTIONAL
REGULATOR

(Verminephrobacter
eiseniae) 		PF13407
(Peripla_BP_4) 		4 LYS A 270
TYR A 324
ASN A 325
LYS A 327
 None
 1.37A 3bjwD-4ry9A:
undetectable		 3bjwD-4ry9A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ug4 CHOLINE SULFATASE

(Sinorhizobium
meliloti) 		PF00884
(Sulfatase)
PF12411
(Choline_sulf_C) 		4 TYR A 123
ASN A  75
PRO A  52
PHE A 312
 None
 1.46A 3bjwD-4ug4A:
undetectable		 3bjwD-4ug4A:
12.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1

(Bothrops
jararacussu) 		PF00068
(Phospholip_A2_1) 		4 LYS A  15
TYR A 103
ASN A 104
LYS A 105
 None
 1.02A 3bjwD-4wtbA:
20.5		 3bjwD-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1

(Bothrops
jararacussu) 		PF00068
(Phospholip_A2_1) 		4 LYS A  15
TYR A 103
ASN A 104
PHE A 114
 None
 0.98A 3bjwD-4wtbA:
20.5		 3bjwD-4wtbA:
56.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xr7 PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN3

(Saccharomyces
cerevisiae) 		no annotation 4 TYR G 812
ASN G 813
LYS G 815
PHE L 552
 None
 0.93A 3bjwD-4xr7G:
undetectable		 3bjwD-4xr7G:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y1y GALECTIN-1

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 ASN A  33
LYS A  43
PRO A  47
PHE A  79
 None
CSO  A  42 ( 3.6A)
None
None
 1.41A 3bjwD-4y1yA:
undetectable		 3bjwD-4y1yA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yeh LECTIN

(Cicer arietinum) 		PF00045
(Hemopexin) 		4 LYS A 136
ASN A  81
LYS A 103
PRO A 101
 None
 1.47A 3bjwD-4yehA:
undetectable		 3bjwD-4yehA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zhb ANKYRIN
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila) 		PF12796
(Ank_2) 		4 TYR A  50
ASN A  83
LYS A  86
PHE A 102
 None
 1.31A 3bjwD-4zhbA:
undetectable		 3bjwD-4zhbA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zpi PUTATIVE
OXIDASE/HYDROXYLASE

(Streptomyces
hygroscopicus) 		PF05721
(PhyH) 		4 ASN A 105
LYS A 161
PRO A 134
PHE A 229
 None
 0.96A 3bjwD-4zpiA:
undetectable		 3bjwD-4zpiA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus 1) 		PF00078
(RVT_1)
PF06815
(RVT_connect)
PF06817
(RVT_thumb) 		4 LYS B 166
PRO B 150
PHE B  77
TRP B 153
 None
 1.32A 3bjwD-5c24B:
undetectable		 3bjwD-5c24B:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c2m PREDICTED PROTEIN

(Nematostella
vectensis) 		PF14517
(Tachylectin) 		4 ASN A 230
LYS A 215
LYS A 216
TRP A 192
 None
 1.39A 3bjwD-5c2mA:
undetectable		 3bjwD-5c2mA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cg0 BETA-GLUCOSIDASE

(Spodoptera
frugiperda) 		PF00232
(Glyco_hydro_1) 		4 TYR A 141
ASN A 186
PHE A 460
TRP A 444
 None
None
TRS  A 603 (-4.1A)
TRS  A 603 ( 4.2A)
 1.45A 3bjwD-5cg0A:
undetectable		 3bjwD-5cg0A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fgl NICR

(Pseudomonas
putida) 		PF00440
(TetR_N) 		4 TYR A  94
ASN A  93
LYS A  90
LYS A  89
 None
 1.36A 3bjwD-5fglA:
undetectable		 3bjwD-5fglA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g4x SH3 AND MULTIPLE
ANKYRIN REPEAT
DOMAINS PROTEIN 3

(Rattus
norvegicus) 		PF12796
(Ank_2)
PF16511
(FERM_f0) 		4 TYR A  53
ASN A  52
PRO A 141
PHE A 119
 EDO  A1354 (-4.6A)
None
None
None
 1.49A 3bjwD-5g4xA:
undetectable		 3bjwD-5g4xA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i8i UREA AMIDOLYASE

(Kluyveromyces
lactis) 		PF00289
(Biotin_carb_N)
PF01425
(Amidase)
PF02626
(CT_A_B)
PF02682
(CT_C_D)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 TYR A 148
ASN A 381
PRO A 272
TRP A 265
 None
 1.42A 3bjwD-5i8iA:
undetectable		 3bjwD-5i8iA:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idi 1,4-BETA-D-GLUCAN
GLUCOHYDROLASE

(Thermotoga
neapolitana) 		PF00232
(Glyco_hydro_1) 		4 TYR A 118
ASN A 163
PHE A 412
TRP A 396
 None
None
ACT  A 501 ( 4.0A)
ACT  A 501 (-3.4A)
 1.44A 3bjwD-5idiA:
undetectable		 3bjwD-5idiA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k8b 8-AMINO-3,8-DIDEOXY-
ALPHA-D-MANNO-OCTULO
SONATE TRANSAMINASE

(Shewanella
oneidensis) 		PF01041
(DegT_DnrJ_EryC1) 		4 ASN A 261
LYS A 262
PRO A   2
PHE A   4
 None
CL  A 503 (-3.0A)
None
None
 1.22A 3bjwD-5k8bA:
undetectable		 3bjwD-5k8bA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE BETA
SUBUNIT
ACETOPHENONE
CARBOXYLASE DELTA
SUBUNIT

(Aromatoleum
aromaticum) 		PF02538
(Hydantoinase_B)
PF08882
(Acetone_carb_G) 		4 TYR C  36
LYS C  37
LYS C  38
PRO A 648
 None
 1.44A 3bjwD-5l9wC:
undetectable		 3bjwD-5l9wC:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lfr MYELIN-ASSOCIATED
GLYCOPROTEIN

(Mus musculus) 		PF08205
(C2-set_2)
PF13927
(Ig_3) 		4 ASN A 266
LYS A 237
PRO A 206
PHE A 204
 None
 1.17A 3bjwD-5lfrA:
undetectable		 3bjwD-5lfrA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m86 TA1207

(Thermoplasma
acidophilum) 		no annotation 4 TYR A 214
LYS A 204
PRO A  42
PHE A  52
 None
 1.44A 3bjwD-5m86A:
undetectable		 3bjwD-5m86A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mlc 50S RIBOSOMAL
PROTEIN L3,
CHLOROPLASTIC

(Spinacia
oleracea) 		PF00297
(Ribosomal_L3) 		4 ASN E 301
LYS E 296
PRO E 294
PHE E 191
 None
C  A2789 ( 2.7A)
None
None
 1.46A 3bjwD-5mlcE:
undetectable		 3bjwD-5mlcE:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n8o DNA HELICASE I

(Escherichia
coli) 		PF07057
(TraI)
PF08751
(TrwC)
PF13604
(AAA_30) 		4 TYR A  16
PRO A 154
PHE A 234
TRP A 277
 None
 1.29A 3bjwD-5n8oA:
undetectable		 3bjwD-5n8oA:
4.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1

(Homo sapiens) 		no annotation 4 TYR A 181
LYS A 185
PRO A 103
PHE A 104
 None
 1.45A 3bjwD-5o9hA:
undetectable		 3bjwD-5o9hA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ogz -

(-) 		no annotation 4 TYR A 120
ASN A 165
PHE A 418
TRP A 402
 None
 1.48A 3bjwD-5ogzA:
undetectable		 3bjwD-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5owc -

(-) 		no annotation 4 TYR A 103
LYS A 106
PRO A 111
PHE A 113
 PEG  A 205 ( 4.2A)
None
None
None
 1.47A 3bjwD-5owcA:
18.7		 3bjwD-5owcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uam ULVAN LYASE-PL25

(Pseudoalteromonas
sp. PLSV) 		PF15892
(BNR_4) 		4 LYS A 432
TYR A 466
LYS A 464
PRO A  84
 None
 1.46A 3bjwD-5uamA:
undetectable		 3bjwD-5uamA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xgz BETA-GLYCOSIDASE

(uncultured
microorganism) 		no annotation 4 TYR A 124
ASN A 169
PHE A 419
TRP A 403
 None
None
GOL  A 501 (-4.3A)
GOL  A 501 (-3.5A)
 1.42A 3bjwD-5xgzA:
undetectable		 3bjwD-5xgzA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y5a KLLA0F20702P

(Kluyveromyces
lactis) 		no annotation 4 ASN A 471
LYS A 470
PRO A 526
PHE A 524
 None
 1.30A 3bjwD-5y5aA:
undetectable		 3bjwD-5y5aA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zal ENDORIBONUCLEASE
DICER

(Homo sapiens) 		no annotation 4 LYS A  79
TYR A1692
ASN A1695
PHE A1610
 None
 1.02A 3bjwD-5zalA:
undetectable		 3bjwD-5zalA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6epe PROTEASOME (PROSOME,
MACROPAIN) 26S
SUBUNIT, NON-ATPASE,
7 (PREDICTED)

(Rattus
norvegicus) 		no annotation 4 LYS U  84
ASN U  77
PRO U  57
PHE U  69
 None
 1.20A 3bjwD-6epeU:
undetectable		 3bjwD-6epeU:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gdt -

(-) 		no annotation 4 LYS A 510
ASN A 496
PRO A 484
PHE A  62
 None
 1.38A 3bjwD-6gdtA:
undetectable		 3bjwD-6gdtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aj6 GYRASE

(Escherichia
coli) 		PF02518
(HATPase_c) 		4 VAL A 120
ILE A  27
GLY A  24
ARG A  22
 None
 0.77A 3bjwF-1aj6A:
undetectable		 3bjwF-1aj6A:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1as4 ANTICHYMOTRYPSIN

(Homo sapiens) 		PF00079
(Serpin) 		4 VAL A 183
ILE A 321
GLY A 320
ARG A 325
 None
 0.91A 3bjwF-1as4A:
undetectable		 3bjwF-1as4A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bgc GRANULOCYTE
COLONY-STIMULATING
FACTOR

(Bos taurus) 		PF16647
(GCSF) 		4 GLN A 146
GLY A 150
ARG A 148
LEU A  36
 None
 0.92A 3bjwF-1bgcA:
undetectable		 3bjwF-1bgcA:
18.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1god PROTEIN
(PHOSPHOLIPASE A2)

(Cerrophidion
godmani) 		PF00068
(Phospholip_A2_1) 		4 LYS A   7
GLN A  11
GLY A  15
LEU A 110
 None
 0.84A 3bjwF-1godA:
20.3		 3bjwF-1godA:
56.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gr0 INOSITOL-3-PHOSPHATE
SYNTHASE

(Mycobacterium
tuberculosis) 		PF01658
(Inos-1-P_synth) 		4 VAL A  65
GLN A 104
GLY A  76
ARG A 105
 None
 0.92A 3bjwF-1gr0A:
undetectable		 3bjwF-1gr0A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR

(Homo sapiens) 		PF00079
(Serpin) 		4 VAL A 377
ILE A 243
GLY A 234
LEU A 366
 None
 0.85A 3bjwF-1imvA:
undetectable		 3bjwF-1imvA:
12.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1jia PHOSPHOLIPASE A2

(Gloydius halys) 		PF00068
(Phospholip_A2_1) 		4 LYS A   7
GLY A  14
ARG A 107
LEU A 110
 None
 0.67A 3bjwF-1jiaA:
22.0		 3bjwF-1jiaA:
51.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kkr 3-METHYLASPARTATE
AMMONIA-LYASE

(Citrobacter
amalonaticus) 		PF05034
(MAAL_N)
PF07476
(MAAL_C) 		4 VAL A 317
ILE A 330
GLY A 358
ARG A 382
 None
 0.84A 3bjwF-1kkrA:
undetectable		 3bjwF-1kkrA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lwu FIBRINOGEN BETA
CHAIN

(Petromyzon
marinus) 		PF00147
(Fibrinogen_C)
PF08702
(Fib_alpha) 		4 VAL B 319
ILE B 248
GLY B 229
ARG B 237
 None
 0.89A 3bjwF-1lwuB:
undetectable		 3bjwF-1lwuB:
14.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mc2 ACUTOHAEMONLYSIN

(Deinagkistrodon
acutus) 		PF00068
(Phospholip_A2_1) 		5 LYS A1007
GLN A1011
GLY A1014
ARG A1107
LEU A1110
 None
 1.09A 3bjwF-1mc2A:
21.3		 3bjwF-1mc2A:
56.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q8k EUKARYOTIC
TRANSLATION
INITIATION FACTOR 2
SUBUNIT 1

(Homo sapiens) 		PF00575
(S1)
PF07541
(EIF_2_alpha) 		4 VAL A 267
ILE A 257
GLY A 214
ARG A 212
 None
 0.85A 3bjwF-1q8kA:
undetectable		 3bjwF-1q8kA:
15.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1s8h PHOSPHOLIPASE A2
HOMOLOG

(Agkistrodon
contortrix) 		PF00068
(Phospholip_A2_1) 		4 GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.41A 3bjwF-1s8hA:
20.4		 3bjwF-1s8hA:
62.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ti8 HEMAGGLUTININ

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 VAL A 272
ILE A 268
GLY A 267
ARG A 109
 None
 0.80A 3bjwF-1ti8A:
undetectable		 3bjwF-1ti8A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9c PRECORRIN-8X METHYL
MUTASE

(Thermus
thermophilus) 		PF02570
(CbiC) 		4 VAL A  56
ILE A  63
GLN A  64
GLY A  66
 None
 0.90A 3bjwF-1v9cA:
undetectable		 3bjwF-1v9cA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w99 PESTICIDIAL CRYSTAL
PROTEIN CRY4BA

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 VAL A 214
LYS A 218
ILE A 221
LEU A 175
 None
 0.68A 3bjwF-1w99A:
undetectable		 3bjwF-1w99A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xwm PHOSPHATE UPTAKE
REGULATOR

(Geobacillus
stearothermophilus) 		PF01895
(PhoU) 		4 VAL A  98
LYS A 102
ILE A 105
GLY A 108
 None
 0.79A 3bjwF-1xwmA:
undetectable		 3bjwF-1xwmA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis) 		PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6) 		4 VAL A 131
ILE A 138
GLN A 139
GLY A 141
 None
 0.78A 3bjwF-1yv9A:
undetectable		 3bjwF-1yv9A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 ILE A1037
GLN A  10
GLY A1038
LEU A1000
 None
 0.62A 3bjwF-2b5mA:
undetectable		 3bjwF-2b5mA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bdv PHAGE-RELATED
CONSERVED
HYPOTHETICAL
PROTEIN, BB2244

(Bordetella
bronchiseptica) 		PF02586
(SRAP) 		4 VAL A  49
ILE A  95
GLY A 131
LEU A 191
 None
 0.66A 3bjwF-2bdvA:
undetectable		 3bjwF-2bdvA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1h DELTA-AMINOLEVULINIC
ACID DEHYDRATASE

(Prosthecochloris
vibrioformis) 		PF00490
(ALAD) 		4 VAL A  67
LYS A  71
GLY A  77
ARG A 328
 None
 0.83A 3bjwF-2c1hA:
undetectable		 3bjwF-2c1hA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dlz PROTEIN VAV-2

(Homo sapiens) 		PF00017
(SH2) 		4 VAL A  68
LYS A  66
ILE A  65
LEU A  32
 None
 0.90A 3bjwF-2dlzA:
undetectable		 3bjwF-2dlzA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fff PENICILLIN-BINDING
PROTEIN 1B

(Streptococcus
pneumoniae) 		PF00905
(Transpeptidase) 		4 ILE B 470
GLN B 474
GLY B 469
LEU B 509
 None
 0.69A 3bjwF-2fffB:
undetectable		 3bjwF-2fffB:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fkz BACTERIOFERRITIN

(Azotobacter
vinelandii) 		PF00210
(Ferritin) 		4 LYS A   5
ILE A   8
GLN A   9
LEU A 120
 None
 0.86A 3bjwF-2fkzA:
undetectable		 3bjwF-2fkzA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fvl ALDO-KETO REDUCTASE
FAMILY 1, MEMBER C4

(Homo sapiens) 		PF00248
(Aldo_ket_red) 		4 VAL A  35
LYS A  39
ILE A  42
GLY A  45
 None
 0.84A 3bjwF-2fvlA:
undetectable		 3bjwF-2fvlA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p7s AMPHINASE-2

(Rana pipiens) 		PF00074
(RnaseA) 		4 VAL A  66
LYS A  68
GLY A 112
LEU A  76
 None
 0.80A 3bjwF-2p7sA:
undetectable		 3bjwF-2p7sA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I

(Escherichia
coli) 		PF00365
(PFK) 		4 VAL A 202
LYS A 206
ILE A 209
GLY A 212
 None
 0.61A 3bjwF-2pfkA:
undetectable		 3bjwF-2pfkA:
15.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ph4 ZHAOERMIATOXIN

(Protobothrops
mangshanensis) 		PF00068
(Phospholip_A2_1) 		5 LYS A   7
GLN A  11
GLY A  15
ARG A 107
LEU A 110
 None
 1.25A 3bjwF-2ph4A:
19.4		 3bjwF-2ph4A:
57.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q1d 2-KETO-3-DEOXY-D-ARA
BINONATE DEHYDRATASE

(Sulfolobus
solfataricus) 		PF01557
(FAA_hydrolase) 		4 VAL X 148
ILE X 279
GLY X 280
LEU X  57
 None
 0.90A 3bjwF-2q1dX:
undetectable		 3bjwF-2q1dX:
16.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		6 LYS A   7
ILE A  10
GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.95A 3bjwF-2qheA:
23.9		 3bjwF-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		6 VAL A   3
ILE A  10
GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.49A 3bjwF-2qheA:
23.9		 3bjwF-2qheA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qzp ACYLAMINO-ACID-RELEA
SING ENZYME

(Aeropyrum
pernix) 		PF00326
(Peptidase_S9) 		4 VAL A  67
ILE A 114
GLY A 128
LEU A 150
 None
 0.93A 3bjwF-2qzpA:
undetectable		 3bjwF-2qzpA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vgi PYRUVATE KINASE
ISOZYMES R/L

(Homo sapiens) 		PF00224
(PK)
PF02887
(PK_C) 		4 VAL A 101
LYS A 105
ILE A 108
GLY A 111
 None
 0.88A 3bjwF-2vgiA:
undetectable		 3bjwF-2vgiA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vmf BETA-MANNOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2) 		4 LYS A 385
GLY A 359
ARG A 633
LEU A 629
 None
 0.86A 3bjwF-2vmfA:
undetectable		 3bjwF-2vmfA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1

(Homo sapiens) 		PF02732
(ERCC4) 		4 VAL B 501
ILE B 545
GLY B 546
ARG B 551
 None
 0.85A 3bjwF-2ziuB:
undetectable		 3bjwF-2ziuB:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a4t PUTATIVE
METHYLTRANSFERASE
MJ0026

(Methanocaldococcus
jannaschii) 		PF01189
(Methyltr_RsmB-F) 		4 VAL A  35
ILE A  54
GLY A  55
LEU A  61
 None
 0.92A 3bjwF-3a4tA:
undetectable		 3bjwF-3a4tA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aib GLUCOSYLTRANSFERASE-
SI

(Streptococcus
mutans) 		PF02324
(Glyco_hydro_70) 		4 VAL A 752
ILE A 707
GLY A 738
LEU A 642
 None
 0.91A 3bjwF-3aibA:
undetectable		 3bjwF-3aibA:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aty PROSTAGLANDIN F2A
SYNTHASE

(Trypanosoma
cruzi) 		PF00724
(Oxidored_FMN) 		4 VAL A 177
LYS A 181
ILE A 184
GLY A 188
 None
 0.90A 3bjwF-3atyA:
undetectable		 3bjwF-3atyA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dh9 THIOREDOXIN
REDUCTASE 1

(Drosophila
melanogaster) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 VAL A 155
ILE A 327
GLY A 289
ARG A 161
 None
 0.81A 3bjwF-3dh9A:
undetectable		 3bjwF-3dh9A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e9y ACETOLACTATE
SYNTHASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 VAL A 545
ILE A 521
GLY A 522
ARG A 156
 None
 0.90A 3bjwF-3e9yA:
undetectable		 3bjwF-3e9yA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fb4 ADENYLATE KINASE

(Jeotgalibacillus
marinus) 		PF00406
(ADK)
PF05191
(ADK_lid) 		4 VAL A  90
ILE A  65
GLY A  66
LEU A  45
 None
 0.85A 3bjwF-3fb4A:
undetectable		 3bjwF-3fb4A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fnb ACYLAMINOACYL
PEPTIDASE SMU_737

(Streptococcus
mutans) 		PF12146
(Hydrolase_4) 		4 VAL A 296
LYS A 300
GLN A 304
GLY A 306
 None
 0.79A 3bjwF-3fnbA:
undetectable		 3bjwF-3fnbA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6d PROTOPORPHYRINOGEN
OXIDASE

(Bacillus
subtilis) 		PF01593
(Amino_oxidase) 		4 VAL A  78
ILE A 241
GLN A 244
LEU A  37
 None
 0.90A 3bjwF-3i6dA:
undetectable		 3bjwF-3i6dA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6r DIHYDROOROTATE
DEHYDROGENASE
HOMOLOG,
MITOCHONDRIAL

(Plasmodium
falciparum) 		PF01180
(DHO_dh) 		4 VAL A 322
LYS A 326
ILE A 329
GLY A 333
 None
 0.68A 3bjwF-3i6rA:
undetectable		 3bjwF-3i6rA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kgw ALANINE-GLYOXYLATE
AMINOTRANSFERASE

(Mus musculus) 		PF00266
(Aminotran_5) 		4 LYS A  83
ILE A  86
GLN A  87
LEU A 306
 None
 0.91A 3bjwF-3kgwA:
undetectable		 3bjwF-3kgwA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kkj AMINE OXIDASE,
FLAVIN-CONTAINING

(Pseudomonas
syringae group
genomosp. 3) 		PF01593
(Amino_oxidase)
PF13450
(NAD_binding_8) 		4 VAL A  69
ILE A  12
ARG A 117
LEU A  30
 None
 0.91A 3bjwF-3kkjA:
undetectable		 3bjwF-3kkjA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kkj AMINE OXIDASE,
FLAVIN-CONTAINING

(Pseudomonas
syringae group
genomosp. 3) 		PF01593
(Amino_oxidase)
PF13450
(NAD_binding_8) 		4 VAL A  69
ILE A  12
GLY A  11
ARG A 117
 None
None
FAD  A 401 (-2.9A)
None
 0.92A 3bjwF-3kkjA:
undetectable		 3bjwF-3kkjA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kxe ANTITOXIN PROTEIN
PARD-1
TOXIN PROTEIN PARE-1

(Caulobacter
vibrioides) 		PF03693
(ParD_antitoxin)
PF05016
(ParE_toxin) 		4 VAL A  75
ILE A  82
GLY C  58
ARG A   8
 None
 0.79A 3bjwF-3kxeA:
undetectable		 3bjwF-3kxeA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l7z PROBABLE EXOSOME
COMPLEX RNA-BINDING
PROTEIN 1

(Sulfolobus
solfataricus) 		no annotation 4 VAL C 188
ILE C 127
GLY C 149
LEU C 120
 None
 0.90A 3bjwF-3l7zC:
undetectable		 3bjwF-3l7zC:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ln3 DIHYDRODIOL
DEHYDROGENASE

(Mus musculus) 		PF00248
(Aldo_ket_red) 		4 ILE A 261
GLN A 262
GLY A 264
LEU A 203
 None
 0.86A 3bjwF-3ln3A:
undetectable		 3bjwF-3ln3A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1c ENVELOPE
GLYCOPROTEIN L

(Human
alphaherpesvirus
2) 		PF05259
(Herpes_UL1)
PF12524
(GlyL_C) 		4 VAL B  61
ILE B  67
GLY B  69
ARG B  86
 None
 0.81A 3bjwF-3m1cB:
undetectable		 3bjwF-3m1cB:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pp7 PYRUVATE KINASE

(Leishmania
mexicana) 		PF00224
(PK)
PF02887
(PK_C) 		4 LYS A  38
ILE A  41
GLN A  42
GLY A  44
 None
 0.84A 3bjwF-3pp7A:
undetectable		 3bjwF-3pp7A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qkw NUCLEOTIDE SUGAR
SYNTHETASE-LIKE
PROTEIN

(Streptococcus
parasanguinis) 		no annotation 4 VAL A  27
ILE A  69
GLN A  71
LEU A  62
 None
 0.68A 3bjwF-3qkwA:
undetectable		 3bjwF-3qkwA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
UBIQUITIN-LIKE
PROTEIN
SMT3,RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Saccharomyces
cerevisiae;
Schizosaccharomyces
pombe) 		PF11976
(Rad60-SLD)
no annotation 		4 VAL A  66
ILE A   6
GLY A   7
LEU B 655
 None
CL  A1003 (-4.1A)
None
None
 0.67A 3bjwF-3tixA:
undetectable		 3bjwF-3tixA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wai MALTOSE-BINDING
PERIPLASMIC PROTEIN,
TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE

(Archaeoglobus
fulgidus;
Escherichia
coli) 		PF13416
(SBP_bac_8) 		4 VAL A 624
ILE A 574
GLY A 573
LEU A 603
 None
 0.70A 3bjwF-3waiA:
undetectable		 3bjwF-3waiA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE

(Archaeoglobus
fulgidus) 		PF02516
(STT3) 		4 VAL A 624
ILE A 574
GLY A 573
LEU A 603
 None
 0.69A 3bjwF-3wajA:
undetectable		 3bjwF-3wajA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wwy D-LACTATE
DEHYDROGENASE

(Fusobacterium
nucleatum) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 VAL A 112
ILE A 231
GLY A 256
LEU A 250
 None
None
GOL  A 405 ( 3.8A)
None
 0.85A 3bjwF-3wwyA:
undetectable		 3bjwF-3wwyA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zri CLPB PROTEIN

(Vibrio cholerae) 		PF02861
(Clp_N) 		4 VAL A  92
ILE A 116
GLY A 114
LEU A 144
 None
 0.85A 3bjwF-3zriA:
undetectable		 3bjwF-3zriA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyy IRON-SULFUR CLUSTER
BINDING PROTEIN

(Carboxydothermus
hydrogenoformans) 		PF00111
(Fer2)
PF14574
(DUF4445) 		4 VAL X 487
ILE X 461
GLY X 460
ARG X 458
 None
 0.82A 3bjwF-3zyyX:
undetectable		 3bjwF-3zyyX:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4av6 K(+)-STIMULATED
PYROPHOSPHATE-ENERGI
ZED SODIUM PUMP

(Thermotoga
maritima) 		PF03030
(H_PPase) 		4 VAL A 698
ILE A 503
GLY A 504
LEU A 448
 None
 0.85A 3bjwF-4av6A:
undetectable		 3bjwF-4av6A:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cr6 N-ACYLMANNOSAMINE
1-DEHYDROGENASE

(Flavobacterium
sp. 141-8) 		PF13561
(adh_short_C2) 		4 VAL A 154
ILE A 151
GLY A  94
LEU A  68
 None
 0.85A 3bjwF-4cr6A:
undetectable		 3bjwF-4cr6A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4exq UROPORPHYRINOGEN
DECARBOXYLASE

(Burkholderia
thailandensis) 		PF01208
(URO-D) 		4 VAL A 249
ILE A 252
GLY A 274
LEU A 262
 None
 0.92A 3bjwF-4exqA:
undetectable		 3bjwF-4exqA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hou INTERFERON-INDUCED
PROTEIN WITH
TETRATRICOPEPTIDE
REPEATS 1

(Homo sapiens) 		PF13181
(TPR_8)
PF13424
(TPR_12) 		4 VAL A 221
ILE A 183
GLY A 180
LEU A 168
 None
 0.90A 3bjwF-4houA:
undetectable		 3bjwF-4houA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4it4 CG17282

(Drosophila
melanogaster) 		no annotation 4 VAL A 158
LYS A 162
ILE A 165
LEU A 173
 None
 0.85A 3bjwF-4it4A:
undetectable		 3bjwF-4it4A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jnh GAG POLYPROTEIN

(Simian foamy
virus) 		PF03276
(Gag_spuma) 		4 VAL A  18
ILE A  36
GLY A  37
ARG A  39
 None
 0.86A 3bjwF-4jnhA:
undetectable		 3bjwF-4jnhA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4omj SEC14-LIKE PROTEIN 2

(Homo sapiens) 		PF00650
(CRAL_TRIO) 		4 VAL A 239
ILE A 258
GLY A  87
LEU A 131
 None
 0.81A 3bjwF-4omjA:
undetectable		 3bjwF-4omjA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2c CRISPR-ASSOCIATED
HELICASE CAS3

(Thermobaculum
terrenum) 		PF00271
(Helicase_C) 		4 VAL A 845
ILE A 939
GLY A 938
LEU A 627
 None
 0.92A 3bjwF-4q2cA:
2.3		 3bjwF-4q2cA:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rnw NADPH DEHYDROGENASE
1

(Saccharomyces
pastorianus) 		PF00724
(Oxidored_FMN) 		4 VAL A 273
LYS A 277
ILE A 280
GLY A 283
 None
 0.84A 3bjwF-4rnwA:
undetectable		 3bjwF-4rnwA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rnx NADPH DEHYDROGENASE
1

(Saccharomyces
pastorianus) 		PF00724
(Oxidored_FMN) 		4 VAL A  23
LYS A  27
ILE A  30
GLY A  33
 None
 0.79A 3bjwF-4rnxA:
undetectable		 3bjwF-4rnxA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tlg SEC14-LIKE PROTEIN 4

(Homo sapiens) 		PF00650
(CRAL_TRIO) 		4 VAL A 239
ILE A 258
GLY A  87
LEU A 131
 None
None
None
EDO  A 513 ( 4.1A)
 0.87A 3bjwF-4tlgA:
undetectable		 3bjwF-4tlgA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uuo CYTOSOLIC MALATE
DEHYDROGENASE

(Trichomonas
vaginalis) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		5 VAL A  85
ILE A 106
GLN A 110
GLY A 105
LEU A 330
 None
 0.85A 3bjwF-4uuoA:
undetectable		 3bjwF-4uuoA:
15.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1

(Bothrops
jararacussu) 		PF00068
(Phospholip_A2_1) 		5 LYS A   7
GLN A  11
GLY A  14
ARG A  97
LEU A 100
 None
 0.81A 3bjwF-4wtbA:
21.5		 3bjwF-4wtbA:
56.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xrl MITOGEN-ACTIVATED
PROTEIN KINASE 1

(Rattus
norvegicus) 		PF00069
(Pkinase) 		4 VAL A 171
ILE A 138
GLY A 134
LEU A 306
 None
 0.91A 3bjwF-4xrlA:
undetectable		 3bjwF-4xrlA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ybq SOLUTE CARRIER
FAMILY 2,
FACILITATED GLUCOSE
TRANSPORTER MEMBER 5

(Rattus
norvegicus) 		PF00083
(Sugar_tr) 		4 VAL A 144
ILE A 398
ARG A 340
LEU A 344
 None
 0.90A 3bjwF-4ybqA:
undetectable		 3bjwF-4ybqA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yd8 PROTEIN PTHB1

(Homo sapiens) 		PF14727
(PHTB1_N) 		4 VAL A 318
ILE A 305
GLY A 306
LEU A 326
 None
 0.82A 3bjwF-4yd8A:
undetectable		 3bjwF-4yd8A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ync NADPH DEHYDROGENASE
1

(Saccharomyces
pastorianus) 		PF00724
(Oxidored_FMN) 		4 VAL A 174
LYS A 178
ILE A 181
GLY A 184
 None
 0.80A 3bjwF-4yncA:
undetectable		 3bjwF-4yncA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z0t OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY

(Brucella ovis) 		PF00106
(adh_short) 		4 VAL A  34
ILE A  78
GLY A  76
ARG A  73
 None
 0.89A 3bjwF-4z0tA:
undetectable		 3bjwF-4z0tA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zpj EXTRACELLULAR
LIGAND-BINDING
RECEPTOR

(Sphaerobacter
thermophilus) 		PF13458
(Peripla_BP_6) 		4 VAL A 167
ILE A 150
GLY A  84
ARG A  82
 None
 0.90A 3bjwF-4zpjA:
undetectable		 3bjwF-4zpjA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ay9 4-O-BETA-D-MANNOSYL-
D-GLUCOSE
PHOSPHORYLASE

(Ruminococcus
albus) 		PF04041
(Glyco_hydro_130) 		4 VAL A 232
ILE A 164
GLY A 142
ARG A 131
 None
 0.82A 3bjwF-5ay9A:
undetectable		 3bjwF-5ay9A:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b1q U14 PROTEIN

(Human
betaherpesvirus
6B) 		PF04637
(Herpes_pp85) 		4 ILE A  88
GLY A  85
ARG A  83
LEU A  63
 None
 0.90A 3bjwF-5b1qA:
undetectable		 3bjwF-5b1qA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN

(Klebsiella
pneumoniae) 		PF00561
(Abhydrolase_1) 		4 LYS A  44
ILE A  45
GLY A  56
LEU A 129
 None
 0.87A 3bjwF-5bovA:
undetectable		 3bjwF-5bovA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czj DIHYDRODIPICOLINATE
SYNTHASE

(Sinorhizobium
meliloti) 		PF00701
(DHDPS) 		4 VAL A  49
LYS A  53
ILE A  56
GLY A  59
 None
 0.75A 3bjwF-5czjA:
undetectable		 3bjwF-5czjA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dan 2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE

(Thermotoga
maritima) 		PF00248
(Aldo_ket_red) 		4 VAL A  38
LYS A  42
ILE A  45
GLY A  48
 None
 0.84A 3bjwF-5danA:
undetectable		 3bjwF-5danA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5elx ATP-DEPENDENT RNA
HELICASE DBP5

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 VAL A 299
ILE A 304
GLN A 306
GLY A 434
 None
 0.72A 3bjwF-5elxA:
undetectable		 3bjwF-5elxA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fcl CRISPR-ASSOCIATED
ENDONUCLEASE CAS1

(Pectobacterium
atrosepticum) 		PF01867
(Cas_Cas1) 		4 VAL A 140
GLN A 175
GLY A 177
ARG A 173
 None
 0.83A 3bjwF-5fclA:
undetectable		 3bjwF-5fclA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fqd DNA DAMAGE-BINDING
PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 ILE A1037
GLN A  10
GLY A1038
LEU A1000
 None
 0.64A 3bjwF-5fqdA:
undetectable		 3bjwF-5fqdA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jw6 ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Aspergillus
fumigatus) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 VAL A 156
ILE A 344
GLY A 314
ARG A 309
 None
 0.78A 3bjwF-5jw6A:
undetectable		 3bjwF-5jw6A:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k3w CPUTA1

(Curtobacterium
pusillum) 		PF01063
(Aminotran_4) 		4 VAL A 199
ILE A 230
GLN A 228
LEU A  82
 None
 0.93A 3bjwF-5k3wA:
undetectable		 3bjwF-5k3wA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lm8 'MULTICOPPER OXIDASE

(Aspergillus
niger) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 140
ILE A  84
GLY A 166
ARG A 290
 None
 0.88A 3bjwF-5lm8A:
undetectable		 3bjwF-5lm8A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mg3 PROTEIN TRANSLOCASE
SUBUNIT SECD

(Escherichia
coli) 		PF02355
(SecD_SecF)
PF07549
(Sec_GG)
PF13721
(SecD-TM1) 		4 VAL D 238
ILE D 233
GLY D 427
LEU D 279
 None
 0.90A 3bjwF-5mg3D:
undetectable		 3bjwF-5mg3D:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5npr UDP-N-ACETYLGLUCOSAM
INE--PEPTIDE
N-ACETYLGLUCOSAMINYL
TRANSFERASE 110 KDA
SUBUNIT

(Homo sapiens) 		no annotation 4 ILE A 876
GLN A 877
GLY A 872
ARG A 867
 None
 0.86A 3bjwF-5nprA:
undetectable		 3bjwF-5nprA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tuc SUS TBC1D15 GAP
DOMAIN

(Sus scrofa) 		PF00566
(RabGAP-TBC) 		4 VAL A 318
LYS A 322
ILE A 325
GLY A 329
 None
 0.72A 3bjwF-5tucA:
undetectable		 3bjwF-5tucA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udb DNA REPLICATION
LICENSING FACTOR
MCM6

(Saccharomyces
cerevisiae) 		PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB) 		4 VAL 6 589
ILE 6 547
GLY 6 546
LEU 6 806
 None
 0.75A 3bjwF-5udb6:
undetectable		 3bjwF-5udb6:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5um6 UBIQUITIN-ACTIVATING
ENZYME E1 1

(Schizosaccharomyces
pombe) 		PF00899
(ThiF)
PF09358
(E1_UFD)
PF10585
(UBA_e1_thiolCys)
PF16190
(E1_FCCH)
PF16191
(E1_4HB) 		4 LYS A 424
ILE A 425
GLY A 450
LEU A 502
 None
 0.80A 3bjwF-5um6A:
undetectable		 3bjwF-5um6A:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2

(Homo sapiens) 		no annotation 4 VAL A   3
GLY A  14
ARG A  98
LEU A 101
 None
None
None
TRS  A 211 (-4.0A)
 0.52A 3bjwF-5wzmA:
20.5		 3bjwF-5wzmA:
29.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		no annotation 4 VAL A 496
ILE A 523
GLY A 524
ARG A 527
 None
 0.91A 3bjwF-5ze4A:
undetectable		 3bjwF-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b0n PGV19 FAB HEAVY
CHAIN
PGV19 LIGHT CHAIN

(Homo sapiens) 		no annotation 4 VAL E  39
GLN D  39
GLY E 100
LEU E   4
 None
 0.90A 3bjwF-6b0nE:
undetectable		 3bjwF-6b0nE:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ce2 -

(-) 		no annotation 4 VAL A   3
GLN A  11
GLY A  15
ARG A 107
 None
 0.55A 3bjwF-6ce2A:
20.8		 3bjwF-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dnh PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33

(Homo sapiens) 		no annotation 4 VAL B 125
ILE B 378
GLY B 351
ARG B 308
 None
 0.90A 3bjwF-6dnhB:
undetectable		 3bjwF-6dnhB:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fnu METHYLENETETRAHYDROF
OLATE REDUCTASE 1

(Saccharomyces
cerevisiae) 		no annotation 4 VAL A 262
ILE A 269
GLN A 270
LEU A 198
 None
 0.66A 3bjwF-6fnuA:
undetectable		 3bjwF-6fnuA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fsf GTPASE-ACTIVATING
PROTEIN BEM3

(Saccharomyces
cerevisiae) 		no annotation 4 ILE A 661
GLN A 668
GLY A 660
ARG A 658
 None
 0.92A 3bjwF-6fsfA:
undetectable		 3bjwF-6fsfA:
22.94