SIMILAR PATTERNS OF AMINO ACIDS FOR 3BJW_F_SVRF502_3
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aor | ALDEHYDE FERREDOXINOXIDOREDUCTASE (Pyrococcusfuriosus) |
PF01314(AFOR_C)PF02730(AFOR_N) | 5 | VAL A 171LEU A 170LYS A 82SER A 83PRO A 84 | None | 1.23A | 3bjwF-1aorA:undetectable | 3bjwF-1aorA:12.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b25 | PROTEIN(FORMALDEHYDEFERREDOXINOXIDOREDUCTASE) (Pyrococcusfuriosus) |
PF01314(AFOR_C)PF02730(AFOR_N) | 5 | VAL A 169LEU A 168LYS A 81SER A 82PRO A 83 | None | 1.13A | 3bjwF-1b25A:0.0 | 3bjwF-1b25A:11.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1esc | ESTERASE (Streptomycesscabiei) |
PF13472(Lipase_GDSL_2) | 5 | VAL A 243LEU A 245GLY A 185SER A 14THR A 16 | None | 1.28A | 3bjwF-1escA:undetectable | 3bjwF-1escA:17.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ezv | UBIQUINOL-CYTOCHROMEC REDUCTASE COMPLEXCORE PROTEIN I (Saccharomycescerevisiae) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 5 | VAL A 53GLY A 51SER A 106PRO A 382THR A 210 | None | 1.26A | 3bjwF-1ezvA:undetectable | 3bjwF-1ezvA:12.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1gmz | PHOSPHOLIPASE A2 (Bothropspirajai) |
PF00068(Phospholip_A2_1) | 5 | GLY A 6LYS A 15PRO A 17PHE A 18PRO A 19 | None | 0.53A | 3bjwF-1gmzA:19.5 | 3bjwF-1gmzA:57.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1gmz | PHOSPHOLIPASE A2 (Bothropspirajai) |
PF00068(Phospholip_A2_1) | 5 | ILE A 9LYS A 15PHE A 18PRO A 19THR A 23 | None | 1.26A | 3bjwF-1gmzA:19.5 | 3bjwF-1gmzA:57.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gq7 | PROCLAVAMINATEAMIDINO HYDROLASE (Streptomycesclavuligerus) |
PF00491(Arginase) | 5 | VAL A 125LEU A 128GLY A 167ILE A 168SER A 147 | None | 1.17A | 3bjwF-1gq7A:0.0 | 3bjwF-1gq7A:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h3j | PEROXIDASE (Coprinopsiscinerea) |
PF00141(peroxidase)PF11895(Peroxidase_ext) | 5 | LEU A 227ILE A 195PRO A 223PRO A 237THR A 221 | None | 1.13A | 3bjwF-1h3jA:undetectable | 3bjwF-1h3jA:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iok | CHAPERONIN 60 (Paracoccusdenitrificans) |
PF00118(Cpn60_TCP1) | 5 | VAL A 107LEU A 104GLY A 103ILE A 99THR A 517 | None | 1.13A | 3bjwF-1iokA:undetectable | 3bjwF-1iokA:11.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j3b | ATP-DEPENDENTPHOSPHOENOLPYRUVATECARBOXYKINASE (Thermusthermophilus) |
PF01293(PEPCK_ATP) | 5 | VAL A 59GLY A 176ILE A 186PRO A 54SER A 53 | None | 1.17A | 3bjwF-1j3bA:undetectable | 3bjwF-1j3bA:12.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kzq | MAJOR SURFACEANTIGEN P30 (Toxoplasmagondii) |
PF04092(SAG) | 5 | LEU A 32GLY A 112ILE A 114SER A 121THR A 18 | None | 1.19A | 3bjwF-1kzqA:undetectable | 3bjwF-1kzqA:16.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lxt | PHOSPHOGLUCOMUTASE(DEPHOSPHO FORM) (Oryctolaguscuniculus) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 5 | VAL A 57LEU A 56GLY A 109ILE A 132LYS A 15 | None | 1.14A | 3bjwF-1lxtA:undetectable | 3bjwF-1lxtA:9.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n21 | (+)-BORNYLDIPHOSPHATE SYNTHASE (Salviaofficinalis) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 5 | LEU A 492GLY A 489ILE A 450PRO A 455SER A 459 | 3AG A 900 (-4.9A)NoneNoneNoneNone | 1.18A | 3bjwF-1n21A:undetectable | 3bjwF-1n21A:11.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1puj | CONSERVEDHYPOTHETICAL PROTEINYLQF (Bacillussubtilis) |
PF01926(MMR_HSR1) | 5 | VAL A 31LEU A 30GLY A 127ILE A 175LYS A 22 | None | 1.09A | 3bjwF-1pujA:undetectable | 3bjwF-1pujA:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qwg | (2R)-PHOSPHO-3-SULFOLACTATE SYNTHASE (Methanocaldococcusjannaschii) |
PF02679(ComA) | 5 | LEU A 23GLY A 22ILE A 52SER A 49PRO A 73 | None | 1.24A | 3bjwF-1qwgA:undetectable | 3bjwF-1qwgA:16.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1s8h | PHOSPHOLIPASE A2HOMOLOG (Agkistrodoncontortrix) |
PF00068(Phospholip_A2_1) | 5 | LEU A 5GLY A 6LYS A 16SER A 21LYS A 115 | None | 0.90A | 3bjwF-1s8hA:20.4 | 3bjwF-1s8hA:62.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1urh | 3-MERCAPTOPYRUVATESULFURTRANSFERASE (Escherichiacoli) |
PF00581(Rhodanese) | 5 | VAL A 246LEU A 247ILE A 117PRO A 101PHE A 98 | None | 1.26A | 3bjwF-1urhA:undetectable | 3bjwF-1urhA:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a00 | POTASSIUM-TRANSPORTING ATPASE B CHAIN (Escherichiacoli) |
no annotation | 5 | VAL A 439LEU A 440GLY A 441ILE A 323PRO A 430 | None | 1.14A | 3bjwF-2a00A:undetectable | 3bjwF-2a00A:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ahw | PUTATIVE ENZYME YDIF (Escherichiacoli) |
PF01144(CoA_trans) | 5 | VAL A 33LEU A 34GLY A 35ILE A 40THR A 44 | None | 1.23A | 3bjwF-2ahwA:undetectable | 3bjwF-2ahwA:12.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aw5 | NADP-DEPENDENT MALICENZYME (Homo sapiens) |
PF00390(malic)PF03949(Malic_M) | 5 | VAL A 466GLY A 464ILE A 513LYS A 512SER A 510 | None | 1.13A | 3bjwF-2aw5A:undetectable | 3bjwF-2aw5A:11.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ex3 | DNA TERMINAL PROTEIN (Bacillus virusphi29) |
PF05435(Phi-29_GP3) | 5 | VAL B 105LEU B 104SER B 165THR B 98LYS B 90 | None | 1.21A | 3bjwF-2ex3B:undetectable | 3bjwF-2ex3B:14.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fji | EXOCYST COMPLEXCOMPONENT SEC6 (Saccharomycescerevisiae) |
PF06046(Sec6) | 5 | LEU 1 603GLY 1 599ILE 1 510LYS 1 509SER 1 511 | None | 1.19A | 3bjwF-2fji1:undetectable | 3bjwF-2fji1:15.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fpg | SUCCINYL-COA LIGASE[GDP-FORMING]ALPHA-CHAIN,MITOCHONDRIAL (Sus scrofa) |
PF00549(Ligase_CoA)PF02629(CoA_binding) | 5 | LEU A 127GLY A 193ILE A 186PHE A 191PRO A 190 | None | 1.19A | 3bjwF-2fpgA:undetectable | 3bjwF-2fpgA:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g7u | TRANSCRIPTIONALREGULATOR (Rhodococcusjostii) |
PF01614(IclR)PF09339(HTH_IclR) | 5 | VAL A 18LEU A 19GLY A 15ILE A 12THR A 51 | None | 1.10A | 3bjwF-2g7uA:undetectable | 3bjwF-2g7uA:15.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i88 | COLICIN-E1 (Escherichiacoli) |
PF01024(Colicin) | 5 | VAL A 479LEU A 482ILE A 451PRO A 462THR A 466 | None | 1.24A | 3bjwF-2i88A:undetectable | 3bjwF-2i88A:17.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2km1 | PROTEIN DRE2 (Saccharomycescerevisiae) |
PF16803(DRE2_N) | 5 | VAL A 80LEU A 81LYS A 44SER A 49THR A 51 | None | 1.23A | 3bjwF-2km1A:undetectable | 3bjwF-2km1A:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ld4 | ANAMORSIN (Homo sapiens) |
PF08241(Methyltransf_11) | 5 | LEU A 67GLY A 66ILE A 47PRO A 98LYS A 114 | None | 1.24A | 3bjwF-2ld4A:undetectable | 3bjwF-2ld4A:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m5i | BH3-INTERACTINGDOMAIN DEATH AGONIST (Homo sapiens) |
PF06393(BID) | 5 | VAL A 106LEU A 105GLY A 104SER A 100SER A 96 | None | 1.22A | 3bjwF-2m5iA:undetectable | 3bjwF-2m5iA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p4q | 6-PHOSPHOGLUCONATEDEHYDROGENASE,DECARBOXYLATING 1 (Saccharomycescerevisiae) |
PF00393(6PGD)PF03446(NAD_binding_2) | 5 | VAL A 172GLY A 143SER A 108PHE A 105PRO A 106 | None | 1.04A | 3bjwF-2p4qA:1.0 | 3bjwF-2p4qA:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qf7 | PYRUVATE CARBOXYLASEPROTEIN (Rhizobium etli) |
PF00289(Biotin_carb_N)PF00364(Biotin_lipoyl)PF00682(HMGL-like)PF02436(PYC_OADA)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | VAL A 230LEU A 222GLY A 223ILE A 277LYS A 1 | None | 1.11A | 3bjwF-2qf7A:undetectable | 3bjwF-2qf7A:7.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2qhe | PHOSPHOLIPASE A2 (Echis carinatus) |
PF00068(Phospholip_A2_1) | 6 | ILE A 9LYS A 16PRO A 18PHE A 19PRO A 20SER A 21 | None | 1.46A | 3bjwF-2qheA:23.9 | 3bjwF-2qheA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2qhe | PHOSPHOLIPASE A2 (Echis carinatus) |
PF00068(Phospholip_A2_1) | 8 | VAL A 2ILE A 10LYS A 16PRO A 18PHE A 19SER A 21THR A 23LYS A 115 | None | 0.74A | 3bjwF-2qheA:23.9 | 3bjwF-2qheA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2qhe | PHOSPHOLIPASE A2 (Echis carinatus) |
PF00068(Phospholip_A2_1) | 10 | VAL A 2LEU A 5GLY A 6ILE A 10LYS A 16PRO A 18PHE A 19PRO A 20SER A 21THR A 23 | None | 0.58A | 3bjwF-2qheA:23.9 | 3bjwF-2qheA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2qhe | PHOSPHOLIPASE A2 (Echis carinatus) |
PF00068(Phospholip_A2_1) | 9 | VAL A 2LEU A 5GLY A 6ILE A 10LYS A 16SER A 17PRO A 18PRO A 20SER A 21 | None | 0.76A | 3bjwF-2qheA:23.9 | 3bjwF-2qheA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xci | 3-DEOXY-D-MANNO-2-OCTULOSONIC ACIDTRANSFERASE (Aquifexaeolicus) |
PF04413(Glycos_transf_N) | 5 | LEU A 300GLY A 306ILE A 285PRO A 288THR A 290 | None | 1.11A | 3bjwF-2xciA:undetectable | 3bjwF-2xciA:15.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xsg | CCMAN5 (Cellulosimicrobiumcellulans) |
PF07971(Glyco_hydro_92) | 5 | VAL A 81LEU A 80GLY A 61ILE A 59LYS A 58 | None | 1.18A | 3bjwF-2xsgA:undetectable | 3bjwF-2xsgA:9.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ywx | PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASECATALYTIC SUBUNIT (Methanocaldococcusjannaschii) |
PF00731(AIRC) | 5 | VAL A 104ILE A 122PRO A 76PHE A 55THR A 73 | None | 1.26A | 3bjwF-2ywxA:undetectable | 3bjwF-2ywxA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bm3 | PSPGI RESTRICTIONENDONUCLEASE (Pyrococcus sp.GI-H) |
PF09019(EcoRII-C) | 5 | VAL A 159GLY A 191ILE A 215PRO A 52SER A 247 | None | 1.25A | 3bjwF-3bm3A:undetectable | 3bjwF-3bm3A:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c2u | XYLOSIDASE/ARABINOSIDASE (Selenomonasruminantium) |
PF04616(Glyco_hydro_43)PF07081(DUF1349) | 5 | ILE A 518SER A 373SER A 376THR A 417LYS A 64 | None | 1.09A | 3bjwF-3c2uA:undetectable | 3bjwF-3c2uA:11.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cji | POLYPROTEIN (Senecavirus A) |
no annotation | 5 | VAL A 237LEU A 43SER A 83PHE A 72THR A 216 | None | 1.14A | 3bjwF-3cjiA:undetectable | 3bjwF-3cjiA:18.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cpi | RAB GDP-DISSOCIATIONINHIBITOR (Saccharomycescerevisiae) |
PF00996(GDI) | 5 | VAL G 266LEU G 267GLY G 277LYS G 7THR G 280 | None | 1.03A | 3bjwF-3cpiG:undetectable | 3bjwF-3cpiG:13.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3dih | PHOSPHOLIPASE A2HOMOLOG, AMMODYTIN L (Viperaammodytes) |
PF00068(Phospholip_A2_1) | 6 | VAL A 2GLY A 6LYS A 15PRO A 17SER A 20LYS A 105 | None | 0.67A | 3bjwF-3dihA:22.5 | 3bjwF-3dihA:64.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fca | CYSTEINE SYNTHASE (Thermusthermophilus) |
PF00291(PALP) | 5 | VAL A 177LEU A 178GLY A 175ILE A 171THR A 146 | None | 1.14A | 3bjwF-3fcaA:undetectable | 3bjwF-3fcaA:16.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h2z | MANNITOL-1-PHOSPHATE5-DEHYDROGENASE (Shigellaflexneri) |
PF01232(Mannitol_dh)PF08125(Mannitol_dh_C) | 5 | VAL A 258LEU A 259GLY A 256ILE A 274THR A 218 | None | 1.24A | 3bjwF-3h2zA:undetectable | 3bjwF-3h2zA:15.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ib3 | COCE/NOND FAMILYHYDROLASE (Staphylococcusaureus) |
PF02129(Peptidase_S15)PF08530(PepX_C) | 5 | VAL A 168LEU A 171GLY A 167PRO A 108THR A 103 | None | 1.14A | 3bjwF-3ib3A:undetectable | 3bjwF-3ib3A:12.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kuq | RHOGTPASE-ACTIVATINGPROTEIN 7 (Homo sapiens) |
PF00620(RhoGAP) | 5 | VAL A1078ILE A1095SER A1094PRO A1092THR A1087 | None | 1.25A | 3bjwF-3kuqA:undetectable | 3bjwF-3kuqA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kzu | 3-OXOACYL-(ACYL-CARRIER-PROTEIN)SYNTHASE II (Brucellamelitensis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | VAL A 201GLY A 240ILE A 345PRO A 14PRO A 53 | None | 1.28A | 3bjwF-3kzuA:undetectable | 3bjwF-3kzuA:13.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lrv | PRE-MRNA-SPLICINGFACTOR 19 (Saccharomycescerevisiae) |
no annotation | 5 | VAL A 337GLY A 336ILE A 289SER A 334PRO A 350 | None | 1.23A | 3bjwF-3lrvA:undetectable | 3bjwF-3lrvA:18.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ntx | CYTOPLASMICL-ASPARAGINASE I (Yersinia pestis) |
PF00710(Asparaginase) | 5 | VAL A 179LEU A 180ILE A 113PHE A 172THR A 161 | None | 1.28A | 3bjwF-3ntxA:undetectable | 3bjwF-3ntxA:13.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o8o | 6-PHOSPHOFRUCTOKINASE SUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00365(PFK) | 5 | VAL A 352LEU A 351GLY A 350ILE A 348PRO A 537 | None | 1.16A | 3bjwF-3o8oA:undetectable | 3bjwF-3o8oA:9.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3puo | DIHYDRODIPICOLINATESYNTHASE (Pseudomonasaeruginosa) |
PF00701(DHDPS) | 5 | VAL A 183LEU A 182GLY A 159ILE A 157SER A 152 | None | 1.03A | 3bjwF-3puoA:undetectable | 3bjwF-3puoA:16.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r6o | 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATEISOMERASE (Mycobacteroidesabscessus) |
PF01557(FAA_hydrolase) | 5 | GLY A 83LYS A 113SER A 114PRO A 115SER A 117 | None | 1.00A | 3bjwF-3r6oA:undetectable | 3bjwF-3r6oA:14.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rbt | GLUTATHIONETRANSFERASE O1 (Bombyx mori) |
PF13410(GST_C_2)PF13417(GST_N_3) | 5 | LEU A 128GLY A 126ILE A 142PHE A 137THR A 133 | None | 1.18A | 3bjwF-3rbtA:undetectable | 3bjwF-3rbtA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s99 | BASIC MEMBRANELIPOPROTEIN (Brucellaabortus) |
PF02608(Bmp) | 5 | VAL A 152GLY A 150ILE A 149PRO A 188SER A 212 | None | 1.27A | 3bjwF-3s99A:undetectable | 3bjwF-3s99A:15.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t0q | AGR253WP (Eremotheciumgossypii) |
PF00225(Kinesin) | 5 | VAL A 606LEU A 605SER A 668SER A 673THR A 675 | None | 1.23A | 3bjwF-3t0qA:undetectable | 3bjwF-3t0qA:17.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t7i | REGULATOR OF TY1TRANSPOSITIONPROTEIN 107 (Saccharomycescerevisiae) |
PF16770(RTT107_BRCT_5)PF16771(RTT107_BRCT_6) | 5 | VAL A 974LEU A 975GLY A 972PRO A 965LYS A1018 | None | 1.15A | 3bjwF-3t7iA:undetectable | 3bjwF-3t7iA:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tl3 | SHORT-CHAIN TYPEDEHYDROGENASE/REDUCTASE (Mycobacteriumulcerans) |
PF00106(adh_short) | 5 | VAL A 117GLY A 113ILE A 109SER A 146THR A 144 | None | 1.14A | 3bjwF-3tl3A:undetectable | 3bjwF-3tl3A:15.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ul4 | CELLULOSOME-ANCHORING PROTEIN (Ruminiclostridiumthermocellum) |
PF00963(Cohesin) | 5 | VAL A 15GLY A 13ILE A 11SER A 28THR A 103 | None | 0.84A | 3bjwF-3ul4A:undetectable | 3bjwF-3ul4A:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w53 | BETA-GLUCOSIDASE (Micrococcusantarcticus) |
PF00232(Glyco_hydro_1) | 5 | VAL A 246LEU A 249ILE A 177PRO A 328SER A 326 | None | 1.07A | 3bjwF-3w53A:undetectable | 3bjwF-3w53A:12.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wbx | PUTATIVE2,5-DIKETO-D-GLUCONIC ACID REDUCTASE (Gluconobacteroxydans) |
PF00248(Aldo_ket_red) | 5 | VAL A 52LEU A 27GLY A 28PRO A 34THR A 37 | None | 1.03A | 3bjwF-3wbxA:undetectable | 3bjwF-3wbxA:16.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wv4 | NON-RIBOSOMALPEPTIDE SYNTHETASE (Streptomyceshalstedii) |
PF00501(AMP-binding) | 5 | VAL A 236LEU A 233GLY A 232PRO A 87THR A 92 | None | 1.22A | 3bjwF-3wv4A:undetectable | 3bjwF-3wv4A:13.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wvn | NON-RIBOSOMALPEPTIDE SYNTHETASE (Streptomyceshalstedii) |
PF00501(AMP-binding) | 5 | VAL A 236LEU A 233GLY A 232PRO A 87THR A 92 | None | 1.19A | 3bjwF-3wvnA:undetectable | 3bjwF-3wvnA:11.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zfv | CRISPR-ASSOCIATEDENDORIBONUCLEASECAS6 1 (Sulfolobussolfataricus) |
PF10040(CRISPR_Cas6) | 5 | LEU A 263GLY A 264ILE A 276LYS A 277THR A 84 | None | 1.20A | 3bjwF-3zfvA:undetectable | 3bjwF-3zfvA:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4by6 | GENERAL NEGATIVEREGULATOR OFTRANSCRIPTIONSUBUNIT 1GENERAL NEGATIVEREGULATOR OFTRANSCRIPTIONSUBUNIT 2 (Saccharomycescerevisiae) |
PF04054(Not1)PF04153(NOT2_3_5) | 5 | VAL A1804GLY A1808ILE A1812PRO B 59THR B 63 | None | 0.87A | 3bjwF-4by6A:undetectable | 3bjwF-4by6A:10.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cjx | C-1-TETRAHYDROFOLATESYNTHASE,CYTOPLASMIC,PUTATIVE (Trypanosomabrucei) |
PF00763(THF_DHG_CYH)PF02882(THF_DHG_CYH_C) | 5 | VAL A 271GLY A 273PRO A 277SER A 281THR A 279 | None9L9 A1300 (-3.4A)9L9 A1300 (-4.1A)None9L9 A1300 ( 4.8A) | 1.28A | 3bjwF-4cjxA:0.8 | 3bjwF-4cjxA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4di4 | TATP(T) (TP0957) (Treponemapallidum) |
PF03480(DctP) | 5 | VAL B 167LEU B 168GLY B 169ILE B 179PRO B 183 | None | 1.24A | 3bjwF-4di4B:undetectable | 3bjwF-4di4B:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dsh | UDP-GALACTOPYRANOSEMUTASE (Trypanosomacruzi) |
PF01593(Amino_oxidase)PF13450(NAD_binding_8) | 5 | VAL A 297GLY A 299SER A 345THR A 329LYS A 311 | None | 1.04A | 3bjwF-4dshA:undetectable | 3bjwF-4dshA:13.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4egt | MAJOR CAPSID PROTEINVP60 (Rabbithemorrhagicdisease virus) |
PF00915(Calici_coat) | 5 | VAL A 407GLY A 410SER A 303PHE A 315SER A 301 | None | 1.13A | 3bjwF-4egtA:undetectable | 3bjwF-4egtA:13.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4evw | NUCLEOSIDE-DIPHOSPHATE-SUGARPYROPHOSPHORYLASE (Vibrio cholerae) |
no annotation | 5 | LEU A 134ILE A 126SER A 127PHE A 123THR A 110 | None | 1.27A | 3bjwF-4evwA:undetectable | 3bjwF-4evwA:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f0u | ALLOPHYCOCYANINALPHA CHAINALLOPHYCOCYANIN,BETA SUBUNIT (Synechococcuselongatus) |
PF00502(Phycobilisome) | 5 | VAL A 100GLY A 98ILE A 107PRO A 106THR B 6 | None | 1.17A | 3bjwF-4f0uA:undetectable | 3bjwF-4f0uA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f92 | U5 SMALL NUCLEARRIBONUCLEOPROTEIN200 KDA HELICASE (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 5 | VAL B 970LEU B 969GLY B 985ILE B 987LYS B 592 | None | 1.23A | 3bjwF-4f92B:undetectable | 3bjwF-4f92B:5.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gkr | NECK AND C-TERMINALMOTOR DOMAIN OF KAR3 ([Candida]glabrata) |
PF00225(Kinesin) | 6 | VAL A 588LEU A 587ILE A 584SER A 650SER A 655THR A 657 | None | 1.38A | 3bjwF-4gkrA:undetectable | 3bjwF-4gkrA:15.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mo9 | PERIPLASMIC BINDINGPROTEIN (Veillonellaparvula) |
PF01497(Peripla_BP_2) | 5 | LEU A 165GLY A 166ILE A 19LYS A 32PRO A 34 | None | 1.14A | 3bjwF-4mo9A:undetectable | 3bjwF-4mo9A:14.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nph | PROBABLE SECRETIONSYSTEM APPARATUS ATPSYNTHASE SSAN (Salmonellaenterica) |
PF00006(ATP-synt_ab) | 5 | GLY A 153ILE A 135PHE A 354PRO A 355THR A 358 | None | 1.20A | 3bjwF-4nphA:undetectable | 3bjwF-4nphA:16.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qrj | PUTATIVE6-PHOSPHOGLUCONOLACTONASE (Bacteroidesuniformis) |
PF10282(Lactonase) | 5 | GLY A 35ILE A 45PRO A 68PRO A 66SER A 84 | NoneNoneNonePEG A 402 (-4.1A)PEG A 402 (-3.5A) | 1.23A | 3bjwF-4qrjA:undetectable | 3bjwF-4qrjA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wis | LIPID SCRAMBLASE ([Nectria]haematococca) |
PF04547(Anoctamin) | 5 | VAL A 337LEU A 336GLY A 339ILE A 343SER A 344 | None | 1.27A | 3bjwF-4wisA:undetectable | 3bjwF-4wisA:10.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4wtb | BASIC PHOSPHOLIPASEA2 HOMOLOGBOTHROPSTOXIN-1 (Bothropsjararacussu) |
PF00068(Phospholip_A2_1) | 6 | LEU A 5GLY A 6LYS A 15PRO A 17SER A 20LYS A 105 | None | 0.76A | 3bjwF-4wtbA:21.5 | 3bjwF-4wtbA:56.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xcg | THERMOSOME SUBUNITBETA (Sulfolobussolfataricus) |
PF00118(Cpn60_TCP1) | 5 | VAL B 359GLY B 374LYS B 379SER B 380THR B 337 | None | 1.24A | 3bjwF-4xcgB:undetectable | 3bjwF-4xcgB:12.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zg5 | 5'-NUCLEOTIDASE SURE (Brucellaabortus) |
no annotation | 5 | LEU D 80GLY D 75ILE D 73PRO D 68THR D 6 | None | 1.22A | 3bjwF-4zg5D:undetectable | 3bjwF-4zg5D:14.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aff | SYMPORTIN 1 (Chaetomiumthermophilum) |
no annotation | 5 | VAL A 512LEU A 513ILE A 485LYS A 483THR A 476 | None | 1.11A | 3bjwF-5affA:undetectable | 3bjwF-5affA:11.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5anb | ELONGATION FACTOR TUGTP-BINDINGDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF14492(EFG_II) | 5 | VAL K 582LEU K 583GLY K 584ILE K 585PHE K 413 | None | 1.26A | 3bjwF-5anbK:undetectable | 3bjwF-5anbK:7.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b04 | PROBABLE TRANSLATIONINITIATION FACTOREIF-2B SUBUNIT GAMMA (Schizosaccharomycespombe) |
PF00483(NTP_transferase) | 5 | LEU E 205GLY E 317ILE E 318PRO E 176SER E 175 | None | 1.25A | 3bjwF-5b04E:undetectable | 3bjwF-5b04E:14.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bnn | CAPSID PROTEIN VP2CAPSID PROTEIN VP3 (Enterovirus D) |
PF00073(Rhv) | 5 | LEU B 217GLY B 218SER C 122PHE B 117THR B 115 | None | 0.93A | 3bjwF-5bnnB:undetectable | 3bjwF-5bnnB:16.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c9i | PROTEIN RELATED TOPENICILLIN ACYLASE (Acidovorax sp.MR-S7) |
PF01804(Penicil_amidase) | 5 | LEU A 543ILE A 686SER A 707SER A 709THR A 728 | None | 1.24A | 3bjwF-5c9iA:undetectable | 3bjwF-5c9iA:9.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cag | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF17145(DUF5119) | 5 | GLY A 63LYS A 59PRO A 58PHE A 56SER A 85 | None | 1.25A | 3bjwF-5cagA:undetectable | 3bjwF-5cagA:16.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5da8 | 60 KDA CHAPERONIN (Chlorobaculumtepidum) |
PF00118(Cpn60_TCP1) | 5 | VAL A 107LEU A 104GLY A 103ILE A 99THR A 517 | None | 1.06A | 3bjwF-5da8A:undetectable | 3bjwF-5da8A:13.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gms | ESTERASE (unculturedbacterium) |
PF07859(Abhydrolase_3) | 5 | LEU A 150GLY A 149ILE A 176PRO A 220PRO A 216 | None | 1.25A | 3bjwF-5gmsA:undetectable | 3bjwF-5gmsA:17.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k8c | 3-DEOXY-ALPHA-D-MANNO-OCTULOSONATE8-OXIDASE (Shewanellaoneidensis) |
PF00465(Fe-ADH) | 5 | VAL A 41LEU A 40GLY A 96ILE A 136LYS A 31 | None | 1.24A | 3bjwF-5k8cA:undetectable | 3bjwF-5k8cA:14.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lu4 | PYRUVATE, PHOSPHATEDIKINASE,CHLOROPLASTIC (Flaveriatrinervia) |
PF00391(PEP-utilizers)PF01326(PPDK_N)PF02896(PEP-utilizers_C) | 5 | VAL A 256LEU A 257GLY A 271SER A 263LYS A 345 | None | 1.14A | 3bjwF-5lu4A:undetectable | 3bjwF-5lu4A:9.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mzn | HELICASESEN1,HELICASE SEN1 (Saccharomycescerevisiae) |
PF13086(AAA_11)PF13087(AAA_12) | 5 | VAL A1427LEU A1368GLY A1369ILE A1343PHE A1374 | NoneEDO A2014 (-4.2A)NoneNoneGOL A2046 ( 4.2A) | 1.02A | 3bjwF-5mznA:undetectable | 3bjwF-5mznA:11.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o8r | L-LYSINE6-MONOOXYGENASEINVOLVED INDESFERRIOXAMINEBIOSYNTHESIS (Erwiniaamylovora) |
no annotation | 5 | VAL A 294LEU A 219ILE A 222SER A 197LYS A 269 | NoneNoneNoneNAP A 502 (-3.1A)NAP A 502 (-2.9A) | 1.28A | 3bjwF-5o8rA:undetectable | 3bjwF-5o8rA:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ore | OCTOPINE-BINDINGPERIPLASMIC PROTEIN (Agrobacteriumtumefaciens) |
no annotation | 5 | LEU A 237GLY A 236PRO A 76SER A 77THR A 79 | None | 0.96A | 3bjwF-5oreA:undetectable | 3bjwF-5oreA:21.49 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5tfv | BASIC PHOSPHOLIPASEA2 MYOTOXIN III (Bothrops asper) |
PF00068(Phospholip_A2_1) | 5 | PRO A 18PHE A 19PRO A 20THR A 23LYS A 115 | NoneNoneNoneNoneTRS A 201 (-3.3A) | 0.71A | 3bjwF-5tfvA:20.8 | 3bjwF-5tfvA:59.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vgm | DIHYDROOROTASE (Vibrio cholerae) |
PF01979(Amidohydro_1) | 5 | VAL A 21LEU A 22GLY A 19PRO A 44THR A 42 | NoneNoneNoneNoneACT A 403 (-4.4A) | 1.25A | 3bjwF-5vgmA:undetectable | 3bjwF-5vgmA:13.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w0s | 60 KDA CHAPERONIN (Escherichiacoli) |
PF00118(Cpn60_TCP1) | 5 | VAL A 107LEU A 104GLY A 103ILE A 99THR A 516 | None | 1.09A | 3bjwF-5w0sA:undetectable | 3bjwF-5w0sA:11.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x6s | ACETYLXYLAN ESTERASEA (Aspergillusawamori) |
PF10503(Esterase_phd) | 5 | GLY A 265ILE A 263SER A 51PRO A 52THR A 55 | NoneNoneNoneMES A 303 ( 4.5A)MES A 303 (-4.6A) | 1.12A | 3bjwF-5x6sA:undetectable | 3bjwF-5x6sA:16.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | RIBOSOMAL PROTEINS15A (Trichomonasvaginalis) |
PF00410(Ribosomal_S8) | 5 | VAL W 73GLY W 127ILE W 125LYS W 124PRO W 77 | NoneNoneNone U 2 650 ( 3.3A) G 2 911 ( 4.9A) | 1.09A | 3bjwF-5xyiW:undetectable | 3bjwF-5xyiW:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ce2 | - (-) |
no annotation | 5 | LEU A 5GLY A 6LYS A 16PRO A 18SER A 21 | PE4 A 201 ( 4.7A)PE4 A 201 (-3.3A)NonePE4 A 201 (-4.6A)None | 0.64A | 3bjwF-6ce2A:20.8 | 3bjwF-6ce2A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cmz | DIHYDROLIPOYLDEHYDROGENASE (Burkholderiacenocepacia) |
no annotation | 5 | VAL A 239LEU A 240GLY A 241LYS A 244THR A 259 | FAD A 503 (-4.1A)NoneNoneNoneNone | 1.23A | 3bjwF-6cmzA:undetectable | 3bjwF-6cmzA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f9n | CLEAVAGE ANDPOLYADENYLATIONSPECIFICITY FACTORSUBUNIT 1 (Homo sapiens) |
no annotation | 5 | ILE A 937PRO A 977PHE A 978THR A 537LYS A 569 | None | 1.27A | 3bjwF-6f9nA:undetectable | 3bjwF-6f9nA:22.22 |