SIMILAR PATTERNS OF AMINO ACIDS FOR 3BJW_F_SVRF502_3

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aor ALDEHYDE FERREDOXIN
OXIDOREDUCTASE


(Pyrococcus
furiosus)
PF01314
(AFOR_C)
PF02730
(AFOR_N)
5 VAL A 171
LEU A 170
LYS A  82
SER A  83
PRO A  84
None
1.23A 3bjwF-1aorA:
undetectable
3bjwF-1aorA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b25 PROTEIN
(FORMALDEHYDE
FERREDOXIN
OXIDOREDUCTASE)


(Pyrococcus
furiosus)
PF01314
(AFOR_C)
PF02730
(AFOR_N)
5 VAL A 169
LEU A 168
LYS A  81
SER A  82
PRO A  83
None
1.13A 3bjwF-1b25A:
0.0
3bjwF-1b25A:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1esc ESTERASE

(Streptomyces
scabiei)
PF13472
(Lipase_GDSL_2)
5 VAL A 243
LEU A 245
GLY A 185
SER A  14
THR A  16
None
1.28A 3bjwF-1escA:
undetectable
3bjwF-1escA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ezv UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I


(Saccharomyces
cerevisiae)
PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
5 VAL A  53
GLY A  51
SER A 106
PRO A 382
THR A 210
None
1.26A 3bjwF-1ezvA:
undetectable
3bjwF-1ezvA:
12.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gmz PHOSPHOLIPASE A2

(Bothrops
pirajai)
PF00068
(Phospholip_A2_1)
5 GLY A   6
LYS A  15
PRO A  17
PHE A  18
PRO A  19
None
0.53A 3bjwF-1gmzA:
19.5
3bjwF-1gmzA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gmz PHOSPHOLIPASE A2

(Bothrops
pirajai)
PF00068
(Phospholip_A2_1)
5 ILE A   9
LYS A  15
PHE A  18
PRO A  19
THR A  23
None
1.26A 3bjwF-1gmzA:
19.5
3bjwF-1gmzA:
57.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gq7 PROCLAVAMINATE
AMIDINO HYDROLASE


(Streptomyces
clavuligerus)
PF00491
(Arginase)
5 VAL A 125
LEU A 128
GLY A 167
ILE A 168
SER A 147
None
1.17A 3bjwF-1gq7A:
0.0
3bjwF-1gq7A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h3j PEROXIDASE

(Coprinopsis
cinerea)
PF00141
(peroxidase)
PF11895
(Peroxidase_ext)
5 LEU A 227
ILE A 195
PRO A 223
PRO A 237
THR A 221
None
1.13A 3bjwF-1h3jA:
undetectable
3bjwF-1h3jA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iok CHAPERONIN 60

(Paracoccus
denitrificans)
PF00118
(Cpn60_TCP1)
5 VAL A 107
LEU A 104
GLY A 103
ILE A  99
THR A 517
None
1.13A 3bjwF-1iokA:
undetectable
3bjwF-1iokA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3b ATP-DEPENDENT
PHOSPHOENOLPYRUVATE
CARBOXYKINASE


(Thermus
thermophilus)
PF01293
(PEPCK_ATP)
5 VAL A  59
GLY A 176
ILE A 186
PRO A  54
SER A  53
None
1.17A 3bjwF-1j3bA:
undetectable
3bjwF-1j3bA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kzq MAJOR SURFACE
ANTIGEN P30


(Toxoplasma
gondii)
PF04092
(SAG)
5 LEU A  32
GLY A 112
ILE A 114
SER A 121
THR A  18
None
1.19A 3bjwF-1kzqA:
undetectable
3bjwF-1kzqA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lxt PHOSPHOGLUCOMUTASE
(DEPHOSPHO FORM)


(Oryctolagus
cuniculus)
PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III)
5 VAL A  57
LEU A  56
GLY A 109
ILE A 132
LYS A  15
None
1.14A 3bjwF-1lxtA:
undetectable
3bjwF-1lxtA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n21 (+)-BORNYL
DIPHOSPHATE SYNTHASE


(Salvia
officinalis)
PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C)
5 LEU A 492
GLY A 489
ILE A 450
PRO A 455
SER A 459
3AG  A 900 (-4.9A)
None
None
None
None
1.18A 3bjwF-1n21A:
undetectable
3bjwF-1n21A:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1puj CONSERVED
HYPOTHETICAL PROTEIN
YLQF


(Bacillus
subtilis)
PF01926
(MMR_HSR1)
5 VAL A  31
LEU A  30
GLY A 127
ILE A 175
LYS A  22
None
1.09A 3bjwF-1pujA:
undetectable
3bjwF-1pujA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qwg (2R)-PHOSPHO-3-SULFO
LACTATE SYNTHASE


(Methanocaldococcus
jannaschii)
PF02679
(ComA)
5 LEU A  23
GLY A  22
ILE A  52
SER A  49
PRO A  73
None
1.24A 3bjwF-1qwgA:
undetectable
3bjwF-1qwgA:
16.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1s8h PHOSPHOLIPASE A2
HOMOLOG


(Agkistrodon
contortrix)
PF00068
(Phospholip_A2_1)
5 LEU A   5
GLY A   6
LYS A  16
SER A  21
LYS A 115
None
0.90A 3bjwF-1s8hA:
20.4
3bjwF-1s8hA:
62.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1urh 3-MERCAPTOPYRUVATE
SULFURTRANSFERASE


(Escherichia
coli)
PF00581
(Rhodanese)
5 VAL A 246
LEU A 247
ILE A 117
PRO A 101
PHE A  98
None
1.26A 3bjwF-1urhA:
undetectable
3bjwF-1urhA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a00 POTASSIUM-TRANSPORTI
NG ATPASE B CHAIN


(Escherichia
coli)
no annotation 5 VAL A 439
LEU A 440
GLY A 441
ILE A 323
PRO A 430
None
1.14A 3bjwF-2a00A:
undetectable
3bjwF-2a00A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ahw PUTATIVE ENZYME YDIF

(Escherichia
coli)
PF01144
(CoA_trans)
5 VAL A  33
LEU A  34
GLY A  35
ILE A  40
THR A  44
None
1.23A 3bjwF-2ahwA:
undetectable
3bjwF-2ahwA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aw5 NADP-DEPENDENT MALIC
ENZYME


(Homo sapiens)
PF00390
(malic)
PF03949
(Malic_M)
5 VAL A 466
GLY A 464
ILE A 513
LYS A 512
SER A 510
None
1.13A 3bjwF-2aw5A:
undetectable
3bjwF-2aw5A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ex3 DNA TERMINAL PROTEIN

(Bacillus virus
phi29)
PF05435
(Phi-29_GP3)
5 VAL B 105
LEU B 104
SER B 165
THR B  98
LYS B  90
None
1.21A 3bjwF-2ex3B:
undetectable
3bjwF-2ex3B:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fji EXOCYST COMPLEX
COMPONENT SEC6


(Saccharomyces
cerevisiae)
PF06046
(Sec6)
5 LEU 1 603
GLY 1 599
ILE 1 510
LYS 1 509
SER 1 511
None
1.19A 3bjwF-2fji1:
undetectable
3bjwF-2fji1:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fpg SUCCINYL-COA LIGASE
[GDP-FORMING]
ALPHA-CHAIN,
MITOCHONDRIAL


(Sus scrofa)
PF00549
(Ligase_CoA)
PF02629
(CoA_binding)
5 LEU A 127
GLY A 193
ILE A 186
PHE A 191
PRO A 190
None
1.19A 3bjwF-2fpgA:
undetectable
3bjwF-2fpgA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g7u TRANSCRIPTIONAL
REGULATOR


(Rhodococcus
jostii)
PF01614
(IclR)
PF09339
(HTH_IclR)
5 VAL A  18
LEU A  19
GLY A  15
ILE A  12
THR A  51
None
1.10A 3bjwF-2g7uA:
undetectable
3bjwF-2g7uA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i88 COLICIN-E1

(Escherichia
coli)
PF01024
(Colicin)
5 VAL A 479
LEU A 482
ILE A 451
PRO A 462
THR A 466
None
1.24A 3bjwF-2i88A:
undetectable
3bjwF-2i88A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2km1 PROTEIN DRE2

(Saccharomyces
cerevisiae)
PF16803
(DRE2_N)
5 VAL A  80
LEU A  81
LYS A  44
SER A  49
THR A  51
None
1.23A 3bjwF-2km1A:
undetectable
3bjwF-2km1A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ld4 ANAMORSIN

(Homo sapiens)
PF08241
(Methyltransf_11)
5 LEU A  67
GLY A  66
ILE A  47
PRO A  98
LYS A 114
None
1.24A 3bjwF-2ld4A:
undetectable
3bjwF-2ld4A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m5i BH3-INTERACTING
DOMAIN DEATH AGONIST


(Homo sapiens)
PF06393
(BID)
5 VAL A 106
LEU A 105
GLY A 104
SER A 100
SER A  96
None
1.22A 3bjwF-2m5iA:
undetectable
3bjwF-2m5iA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4q 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING 1


(Saccharomyces
cerevisiae)
PF00393
(6PGD)
PF03446
(NAD_binding_2)
5 VAL A 172
GLY A 143
SER A 108
PHE A 105
PRO A 106
None
1.04A 3bjwF-2p4qA:
1.0
3bjwF-2p4qA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qf7 PYRUVATE CARBOXYLASE
PROTEIN


(Rhizobium etli)
PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF00682
(HMGL-like)
PF02436
(PYC_OADA)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2)
5 VAL A 230
LEU A 222
GLY A 223
ILE A 277
LYS A   1
None
1.11A 3bjwF-2qf7A:
undetectable
3bjwF-2qf7A:
7.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus)
PF00068
(Phospholip_A2_1)
6 ILE A   9
LYS A  16
PRO A  18
PHE A  19
PRO A  20
SER A  21
None
1.46A 3bjwF-2qheA:
23.9
3bjwF-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus)
PF00068
(Phospholip_A2_1)
8 VAL A   2
ILE A  10
LYS A  16
PRO A  18
PHE A  19
SER A  21
THR A  23
LYS A 115
None
0.74A 3bjwF-2qheA:
23.9
3bjwF-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus)
PF00068
(Phospholip_A2_1)
10 VAL A   2
LEU A   5
GLY A   6
ILE A  10
LYS A  16
PRO A  18
PHE A  19
PRO A  20
SER A  21
THR A  23
None
0.58A 3bjwF-2qheA:
23.9
3bjwF-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus)
PF00068
(Phospholip_A2_1)
9 VAL A   2
LEU A   5
GLY A   6
ILE A  10
LYS A  16
SER A  17
PRO A  18
PRO A  20
SER A  21
None
0.76A 3bjwF-2qheA:
23.9
3bjwF-2qheA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xci 3-DEOXY-D-MANNO-2-OC
TULOSONIC ACID
TRANSFERASE


(Aquifex
aeolicus)
PF04413
(Glycos_transf_N)
5 LEU A 300
GLY A 306
ILE A 285
PRO A 288
THR A 290
None
1.11A 3bjwF-2xciA:
undetectable
3bjwF-2xciA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsg CCMAN5

(Cellulosimicrobium
cellulans)
PF07971
(Glyco_hydro_92)
5 VAL A  81
LEU A  80
GLY A  61
ILE A  59
LYS A  58
None
1.18A 3bjwF-2xsgA:
undetectable
3bjwF-2xsgA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywx PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
CATALYTIC SUBUNIT


(Methanocaldococcus
jannaschii)
PF00731
(AIRC)
5 VAL A 104
ILE A 122
PRO A  76
PHE A  55
THR A  73
None
1.26A 3bjwF-2ywxA:
undetectable
3bjwF-2ywxA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bm3 PSPGI RESTRICTION
ENDONUCLEASE


(Pyrococcus sp.
GI-H)
PF09019
(EcoRII-C)
5 VAL A 159
GLY A 191
ILE A 215
PRO A  52
SER A 247
None
1.25A 3bjwF-3bm3A:
undetectable
3bjwF-3bm3A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c2u XYLOSIDASE/ARABINOSI
DASE


(Selenomonas
ruminantium)
PF04616
(Glyco_hydro_43)
PF07081
(DUF1349)
5 ILE A 518
SER A 373
SER A 376
THR A 417
LYS A  64
None
1.09A 3bjwF-3c2uA:
undetectable
3bjwF-3c2uA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cji POLYPROTEIN

(Senecavirus A)
no annotation 5 VAL A 237
LEU A  43
SER A  83
PHE A  72
THR A 216
None
1.14A 3bjwF-3cjiA:
undetectable
3bjwF-3cjiA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cpi RAB GDP-DISSOCIATION
INHIBITOR


(Saccharomyces
cerevisiae)
PF00996
(GDI)
5 VAL G 266
LEU G 267
GLY G 277
LYS G   7
THR G 280
None
1.03A 3bjwF-3cpiG:
undetectable
3bjwF-3cpiG:
13.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L


(Vipera
ammodytes)
PF00068
(Phospholip_A2_1)
6 VAL A   2
GLY A   6
LYS A  15
PRO A  17
SER A  20
LYS A 105
None
0.67A 3bjwF-3dihA:
22.5
3bjwF-3dihA:
64.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fca CYSTEINE SYNTHASE

(Thermus
thermophilus)
PF00291
(PALP)
5 VAL A 177
LEU A 178
GLY A 175
ILE A 171
THR A 146
None
1.14A 3bjwF-3fcaA:
undetectable
3bjwF-3fcaA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2z MANNITOL-1-PHOSPHATE
5-DEHYDROGENASE


(Shigella
flexneri)
PF01232
(Mannitol_dh)
PF08125
(Mannitol_dh_C)
5 VAL A 258
LEU A 259
GLY A 256
ILE A 274
THR A 218
None
1.24A 3bjwF-3h2zA:
undetectable
3bjwF-3h2zA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ib3 COCE/NOND FAMILY
HYDROLASE


(Staphylococcus
aureus)
PF02129
(Peptidase_S15)
PF08530
(PepX_C)
5 VAL A 168
LEU A 171
GLY A 167
PRO A 108
THR A 103
None
1.14A 3bjwF-3ib3A:
undetectable
3bjwF-3ib3A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kuq RHO
GTPASE-ACTIVATING
PROTEIN 7


(Homo sapiens)
PF00620
(RhoGAP)
5 VAL A1078
ILE A1095
SER A1094
PRO A1092
THR A1087
None
1.25A 3bjwF-3kuqA:
undetectable
3bjwF-3kuqA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II


(Brucella
melitensis)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
5 VAL A 201
GLY A 240
ILE A 345
PRO A  14
PRO A  53
None
1.28A 3bjwF-3kzuA:
undetectable
3bjwF-3kzuA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lrv PRE-MRNA-SPLICING
FACTOR 19


(Saccharomyces
cerevisiae)
no annotation 5 VAL A 337
GLY A 336
ILE A 289
SER A 334
PRO A 350
None
1.23A 3bjwF-3lrvA:
undetectable
3bjwF-3lrvA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ntx CYTOPLASMIC
L-ASPARAGINASE I


(Yersinia pestis)
PF00710
(Asparaginase)
5 VAL A 179
LEU A 180
ILE A 113
PHE A 172
THR A 161
None
1.28A 3bjwF-3ntxA:
undetectable
3bjwF-3ntxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT ALPHA


(Saccharomyces
cerevisiae)
PF00365
(PFK)
5 VAL A 352
LEU A 351
GLY A 350
ILE A 348
PRO A 537
None
1.16A 3bjwF-3o8oA:
undetectable
3bjwF-3o8oA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3puo DIHYDRODIPICOLINATE
SYNTHASE


(Pseudomonas
aeruginosa)
PF00701
(DHDPS)
5 VAL A 183
LEU A 182
GLY A 159
ILE A 157
SER A 152
None
1.03A 3bjwF-3puoA:
undetectable
3bjwF-3puoA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r6o 2-HYDROXYHEPTA-2,4-D
IENE-1,
7-DIOATEISOMERASE


(Mycobacteroides
abscessus)
PF01557
(FAA_hydrolase)
5 GLY A  83
LYS A 113
SER A 114
PRO A 115
SER A 117
None
1.00A 3bjwF-3r6oA:
undetectable
3bjwF-3r6oA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rbt GLUTATHIONE
TRANSFERASE O1


(Bombyx mori)
PF13410
(GST_C_2)
PF13417
(GST_N_3)
5 LEU A 128
GLY A 126
ILE A 142
PHE A 137
THR A 133
None
1.18A 3bjwF-3rbtA:
undetectable
3bjwF-3rbtA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s99 BASIC MEMBRANE
LIPOPROTEIN


(Brucella
abortus)
PF02608
(Bmp)
5 VAL A 152
GLY A 150
ILE A 149
PRO A 188
SER A 212
None
1.27A 3bjwF-3s99A:
undetectable
3bjwF-3s99A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t0q AGR253WP

(Eremothecium
gossypii)
PF00225
(Kinesin)
5 VAL A 606
LEU A 605
SER A 668
SER A 673
THR A 675
None
1.23A 3bjwF-3t0qA:
undetectable
3bjwF-3t0qA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t7i REGULATOR OF TY1
TRANSPOSITION
PROTEIN 107


(Saccharomyces
cerevisiae)
PF16770
(RTT107_BRCT_5)
PF16771
(RTT107_BRCT_6)
5 VAL A 974
LEU A 975
GLY A 972
PRO A 965
LYS A1018
None
1.15A 3bjwF-3t7iA:
undetectable
3bjwF-3t7iA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tl3 SHORT-CHAIN TYPE
DEHYDROGENASE/REDUCT
ASE


(Mycobacterium
ulcerans)
PF00106
(adh_short)
5 VAL A 117
GLY A 113
ILE A 109
SER A 146
THR A 144
None
1.14A 3bjwF-3tl3A:
undetectable
3bjwF-3tl3A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ul4 CELLULOSOME-ANCHORIN
G PROTEIN


(Ruminiclostridium
thermocellum)
PF00963
(Cohesin)
5 VAL A  15
GLY A  13
ILE A  11
SER A  28
THR A 103
None
0.84A 3bjwF-3ul4A:
undetectable
3bjwF-3ul4A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w53 BETA-GLUCOSIDASE

(Micrococcus
antarcticus)
PF00232
(Glyco_hydro_1)
5 VAL A 246
LEU A 249
ILE A 177
PRO A 328
SER A 326
None
1.07A 3bjwF-3w53A:
undetectable
3bjwF-3w53A:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE


(Gluconobacter
oxydans)
PF00248
(Aldo_ket_red)
5 VAL A  52
LEU A  27
GLY A  28
PRO A  34
THR A  37
None
1.03A 3bjwF-3wbxA:
undetectable
3bjwF-3wbxA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wv4 NON-RIBOSOMAL
PEPTIDE SYNTHETASE


(Streptomyces
halstedii)
PF00501
(AMP-binding)
5 VAL A 236
LEU A 233
GLY A 232
PRO A  87
THR A  92
None
1.22A 3bjwF-3wv4A:
undetectable
3bjwF-3wv4A:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wvn NON-RIBOSOMAL
PEPTIDE SYNTHETASE


(Streptomyces
halstedii)
PF00501
(AMP-binding)
5 VAL A 236
LEU A 233
GLY A 232
PRO A  87
THR A  92
None
1.19A 3bjwF-3wvnA:
undetectable
3bjwF-3wvnA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zfv CRISPR-ASSOCIATED
ENDORIBONUCLEASE
CAS6 1


(Sulfolobus
solfataricus)
PF10040
(CRISPR_Cas6)
5 LEU A 263
GLY A 264
ILE A 276
LYS A 277
THR A  84
None
1.20A 3bjwF-3zfvA:
undetectable
3bjwF-3zfvA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4by6 GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 1
GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 2


(Saccharomyces
cerevisiae)
PF04054
(Not1)
PF04153
(NOT2_3_5)
5 VAL A1804
GLY A1808
ILE A1812
PRO B  59
THR B  63
None
0.87A 3bjwF-4by6A:
undetectable
3bjwF-4by6A:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cjx C-1-TETRAHYDROFOLATE
SYNTHASE,
CYTOPLASMIC,
PUTATIVE


(Trypanosoma
brucei)
PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C)
5 VAL A 271
GLY A 273
PRO A 277
SER A 281
THR A 279
None
9L9  A1300 (-3.4A)
9L9  A1300 (-4.1A)
None
9L9  A1300 ( 4.8A)
1.28A 3bjwF-4cjxA:
0.8
3bjwF-4cjxA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4di4 TATP(T) (TP0957)

(Treponema
pallidum)
PF03480
(DctP)
5 VAL B 167
LEU B 168
GLY B 169
ILE B 179
PRO B 183
None
1.24A 3bjwF-4di4B:
undetectable
3bjwF-4di4B:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dsh UDP-GALACTOPYRANOSE
MUTASE


(Trypanosoma
cruzi)
PF01593
(Amino_oxidase)
PF13450
(NAD_binding_8)
5 VAL A 297
GLY A 299
SER A 345
THR A 329
LYS A 311
None
1.04A 3bjwF-4dshA:
undetectable
3bjwF-4dshA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4egt MAJOR CAPSID PROTEIN
VP60


(Rabbit
hemorrhagic
disease virus)
PF00915
(Calici_coat)
5 VAL A 407
GLY A 410
SER A 303
PHE A 315
SER A 301
None
1.13A 3bjwF-4egtA:
undetectable
3bjwF-4egtA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4evw NUCLEOSIDE-DIPHOSPHA
TE-SUGAR
PYROPHOSPHORYLASE


(Vibrio cholerae)
no annotation 5 LEU A 134
ILE A 126
SER A 127
PHE A 123
THR A 110
None
1.27A 3bjwF-4evwA:
undetectable
3bjwF-4evwA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0u ALLOPHYCOCYANIN
ALPHA CHAIN
ALLOPHYCOCYANIN,
BETA SUBUNIT


(Synechococcus
elongatus)
PF00502
(Phycobilisome)
5 VAL A 100
GLY A  98
ILE A 107
PRO A 106
THR B   6
None
1.17A 3bjwF-4f0uA:
undetectable
3bjwF-4f0uA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f92 U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE


(Homo sapiens)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63)
5 VAL B 970
LEU B 969
GLY B 985
ILE B 987
LYS B 592
None
1.23A 3bjwF-4f92B:
undetectable
3bjwF-4f92B:
5.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gkr NECK AND C-TERMINAL
MOTOR DOMAIN OF KAR3


([Candida]
glabrata)
PF00225
(Kinesin)
6 VAL A 588
LEU A 587
ILE A 584
SER A 650
SER A 655
THR A 657
None
1.38A 3bjwF-4gkrA:
undetectable
3bjwF-4gkrA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mo9 PERIPLASMIC BINDING
PROTEIN


(Veillonella
parvula)
PF01497
(Peripla_BP_2)
5 LEU A 165
GLY A 166
ILE A  19
LYS A  32
PRO A  34
None
1.14A 3bjwF-4mo9A:
undetectable
3bjwF-4mo9A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nph PROBABLE SECRETION
SYSTEM APPARATUS ATP
SYNTHASE SSAN


(Salmonella
enterica)
PF00006
(ATP-synt_ab)
5 GLY A 153
ILE A 135
PHE A 354
PRO A 355
THR A 358
None
1.20A 3bjwF-4nphA:
undetectable
3bjwF-4nphA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE


(Bacteroides
uniformis)
PF10282
(Lactonase)
5 GLY A  35
ILE A  45
PRO A  68
PRO A  66
SER A  84
None
None
None
PEG  A 402 (-4.1A)
PEG  A 402 (-3.5A)
1.23A 3bjwF-4qrjA:
undetectable
3bjwF-4qrjA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wis LIPID SCRAMBLASE

([Nectria]
haematococca)
PF04547
(Anoctamin)
5 VAL A 337
LEU A 336
GLY A 339
ILE A 343
SER A 344
None
1.27A 3bjwF-4wisA:
undetectable
3bjwF-4wisA:
10.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1


(Bothrops
jararacussu)
PF00068
(Phospholip_A2_1)
6 LEU A   5
GLY A   6
LYS A  15
PRO A  17
SER A  20
LYS A 105
None
0.76A 3bjwF-4wtbA:
21.5
3bjwF-4wtbA:
56.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xcg THERMOSOME SUBUNIT
BETA


(Sulfolobus
solfataricus)
PF00118
(Cpn60_TCP1)
5 VAL B 359
GLY B 374
LYS B 379
SER B 380
THR B 337
None
1.24A 3bjwF-4xcgB:
undetectable
3bjwF-4xcgB:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zg5 5'-NUCLEOTIDASE SURE

(Brucella
abortus)
no annotation 5 LEU D  80
GLY D  75
ILE D  73
PRO D  68
THR D   6
None
1.22A 3bjwF-4zg5D:
undetectable
3bjwF-4zg5D:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aff SYMPORTIN 1

(Chaetomium
thermophilum)
no annotation 5 VAL A 512
LEU A 513
ILE A 485
LYS A 483
THR A 476
None
1.11A 3bjwF-5affA:
undetectable
3bjwF-5affA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5anb ELONGATION FACTOR TU
GTP-BINDING
DOMAIN-CONTAINING
PROTEIN 1


(Homo sapiens)
PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF14492
(EFG_II)
5 VAL K 582
LEU K 583
GLY K 584
ILE K 585
PHE K 413
None
1.26A 3bjwF-5anbK:
undetectable
3bjwF-5anbK:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b04 PROBABLE TRANSLATION
INITIATION FACTOR
EIF-2B SUBUNIT GAMMA


(Schizosaccharomyces
pombe)
PF00483
(NTP_transferase)
5 LEU E 205
GLY E 317
ILE E 318
PRO E 176
SER E 175
None
1.25A 3bjwF-5b04E:
undetectable
3bjwF-5b04E:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnn CAPSID PROTEIN VP2
CAPSID PROTEIN VP3


(Enterovirus D)
PF00073
(Rhv)
5 LEU B 217
GLY B 218
SER C 122
PHE B 117
THR B 115
None
0.93A 3bjwF-5bnnB:
undetectable
3bjwF-5bnnB:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE


(Acidovorax sp.
MR-S7)
PF01804
(Penicil_amidase)
5 LEU A 543
ILE A 686
SER A 707
SER A 709
THR A 728
None
1.24A 3bjwF-5c9iA:
undetectable
3bjwF-5c9iA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cag UNCHARACTERIZED
PROTEIN


(Bacteroides
ovatus)
PF17145
(DUF5119)
5 GLY A  63
LYS A  59
PRO A  58
PHE A  56
SER A  85
None
1.25A 3bjwF-5cagA:
undetectable
3bjwF-5cagA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5da8 60 KDA CHAPERONIN

(Chlorobaculum
tepidum)
PF00118
(Cpn60_TCP1)
5 VAL A 107
LEU A 104
GLY A 103
ILE A  99
THR A 517
None
1.06A 3bjwF-5da8A:
undetectable
3bjwF-5da8A:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gms ESTERASE

(uncultured
bacterium)
PF07859
(Abhydrolase_3)
5 LEU A 150
GLY A 149
ILE A 176
PRO A 220
PRO A 216
None
1.25A 3bjwF-5gmsA:
undetectable
3bjwF-5gmsA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k8c 3-DEOXY-ALPHA-D-MANN
O-OCTULOSONATE
8-OXIDASE


(Shewanella
oneidensis)
PF00465
(Fe-ADH)
5 VAL A  41
LEU A  40
GLY A  96
ILE A 136
LYS A  31
None
1.24A 3bjwF-5k8cA:
undetectable
3bjwF-5k8cA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lu4 PYRUVATE, PHOSPHATE
DIKINASE,
CHLOROPLASTIC


(Flaveria
trinervia)
PF00391
(PEP-utilizers)
PF01326
(PPDK_N)
PF02896
(PEP-utilizers_C)
5 VAL A 256
LEU A 257
GLY A 271
SER A 263
LYS A 345
None
1.14A 3bjwF-5lu4A:
undetectable
3bjwF-5lu4A:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzn HELICASE
SEN1,HELICASE SEN1


(Saccharomyces
cerevisiae)
PF13086
(AAA_11)
PF13087
(AAA_12)
5 VAL A1427
LEU A1368
GLY A1369
ILE A1343
PHE A1374
None
EDO  A2014 (-4.2A)
None
None
GOL  A2046 ( 4.2A)
1.02A 3bjwF-5mznA:
undetectable
3bjwF-5mznA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o8r L-LYSINE
6-MONOOXYGENASE
INVOLVED IN
DESFERRIOXAMINE
BIOSYNTHESIS


(Erwinia
amylovora)
no annotation 5 VAL A 294
LEU A 219
ILE A 222
SER A 197
LYS A 269
None
None
None
NAP  A 502 (-3.1A)
NAP  A 502 (-2.9A)
1.28A 3bjwF-5o8rA:
undetectable
3bjwF-5o8rA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ore OCTOPINE-BINDING
PERIPLASMIC PROTEIN


(Agrobacterium
tumefaciens)
no annotation 5 LEU A 237
GLY A 236
PRO A  76
SER A  77
THR A  79
None
0.96A 3bjwF-5oreA:
undetectable
3bjwF-5oreA:
21.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III


(Bothrops asper)
PF00068
(Phospholip_A2_1)
5 PRO A  18
PHE A  19
PRO A  20
THR A  23
LYS A 115
None
None
None
None
TRS  A 201 (-3.3A)
0.71A 3bjwF-5tfvA:
20.8
3bjwF-5tfvA:
59.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vgm DIHYDROOROTASE

(Vibrio cholerae)
PF01979
(Amidohydro_1)
5 VAL A  21
LEU A  22
GLY A  19
PRO A  44
THR A  42
None
None
None
None
ACT  A 403 (-4.4A)
1.25A 3bjwF-5vgmA:
undetectable
3bjwF-5vgmA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w0s 60 KDA CHAPERONIN

(Escherichia
coli)
PF00118
(Cpn60_TCP1)
5 VAL A 107
LEU A 104
GLY A 103
ILE A  99
THR A 516
None
1.09A 3bjwF-5w0sA:
undetectable
3bjwF-5w0sA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x6s ACETYLXYLAN ESTERASE
A


(Aspergillus
awamori)
PF10503
(Esterase_phd)
5 GLY A 265
ILE A 263
SER A  51
PRO A  52
THR A  55
None
None
None
MES  A 303 ( 4.5A)
MES  A 303 (-4.6A)
1.12A 3bjwF-5x6sA:
undetectable
3bjwF-5x6sA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi RIBOSOMAL PROTEIN
S15A


(Trichomonas
vaginalis)
PF00410
(Ribosomal_S8)
5 VAL W  73
GLY W 127
ILE W 125
LYS W 124
PRO W  77
None
None
None
U  2 650 ( 3.3A)
G  2 911 ( 4.9A)
1.09A 3bjwF-5xyiW:
undetectable
3bjwF-5xyiW:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ce2 -

(-)
no annotation 5 LEU A   5
GLY A   6
LYS A  16
PRO A  18
SER A  21
PE4  A 201 ( 4.7A)
PE4  A 201 (-3.3A)
None
PE4  A 201 (-4.6A)
None
0.64A 3bjwF-6ce2A:
20.8
3bjwF-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cmz DIHYDROLIPOYL
DEHYDROGENASE


(Burkholderia
cenocepacia)
no annotation 5 VAL A 239
LEU A 240
GLY A 241
LYS A 244
THR A 259
FAD  A 503 (-4.1A)
None
None
None
None
1.23A 3bjwF-6cmzA:
undetectable
3bjwF-6cmzA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1


(Homo sapiens)
no annotation 5 ILE A 937
PRO A 977
PHE A 978
THR A 537
LYS A 569
None
1.27A 3bjwF-6f9nA:
undetectable
3bjwF-6f9nA:
22.22