SIMILAR PATTERNS OF AMINO ACIDS FOR 3BJW_E_SVRE510_3

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e0t PYRUVATE KINASE

(Escherichia
coli) 		PF00224
(PK)
PF02887
(PK_C) 		4 VAL A   7
VAL A  30
THR A 306
THR A   9
 None
 1.26A 3bjwG-1e0tA:
0.0		 3bjwG-1e0tA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fux HYPOTHETICAL 19.5
KDA PROTEIN IN
EMRE-RUS INTERGENIC
REGION

(Escherichia
coli) 		PF01161
(PBP) 		4 VAL A  67
VAL A  93
THR A 127
THR A  65
 None
 1.07A 3bjwG-1fuxA:
0.0		 3bjwG-1fuxA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h0h FORMATE
DEHYDROGENASE
SUBUNIT ALPHA

(Desulfovibrio
gigas) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 VAL A 905
THR A 975
THR A 954
ARG A 906
 None
None
2MD  A1001 ( 4.4A)
None
 1.23A 3bjwG-1h0hA:
0.0		 3bjwG-1h0hA:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h2b ALCOHOL
DEHYDROGENASE

(Aeropyrum
pernix) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 VAL A 257
VAL A 190
THR A 271
THR A 183
 None
 1.28A 3bjwG-1h2bA:
0.0		 3bjwG-1h2bA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i2l 4-AMINO-4-DEOXYCHORI
SMATE LYASE

(Escherichia
coli) 		PF01063
(Aminotran_4) 		4 VAL A 187
VAL A 186
THR A 256
THR A 189
 None
 1.26A 3bjwG-1i2lA:
0.0		 3bjwG-1i2lA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lqt FPRA

(Mycobacterium
tuberculosis) 		PF07992
(Pyr_redox_2) 		4 VAL A 442
THR A  44
THR A 176
ARG A 439
 None
 0.86A 3bjwG-1lqtA:
0.0		 3bjwG-1lqtA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n8p CYSTATHIONINE
GAMMA-LYASE

(Saccharomyces
cerevisiae) 		PF01053
(Cys_Met_Meta_PP) 		4 VAL A 198
VAL A 197
THR A  85
THR A 180
 None
None
None
PLP  A 400 ( 4.1A)
 1.10A 3bjwG-1n8pA:
0.0		 3bjwG-1n8pA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nyo IMMUNOGENIC PROTEIN
MPT70

(Mycobacterium
tuberculosis) 		PF02469
(Fasciclin) 		4 VAL A 102
VAL A 103
THR A 147
THR A  99
 None
 1.25A 3bjwG-1nyoA:
undetectable		 3bjwG-1nyoA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v84 GALACTOSYLGALACTOSYL
XYLOSYLPROTEIN
3-BETA-GLUCURONOSYLT
RANSFERASE 1

(Homo sapiens) 		PF03360
(Glyco_transf_43) 		4 VAL A 112
THR A 137
THR A  85
ARG A 209
 None
 1.28A 3bjwG-1v84A:
0.0		 3bjwG-1v84A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wql IRON-SULFUR PROTEIN
LARGE SUBUNIT OF
CUMENE DIOXYGENASE

(Pseudomonas
fluorescens) 		PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A) 		4 VAL A  86
VAL A  87
THR A 168
THR A  76
 None
 1.12A 3bjwG-1wqlA:
undetectable		 3bjwG-1wqlA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y9g EXO-INULINASE

(Aspergillus
awamori) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 VAL A 203
VAL A 204
THR A 129
THR A 217
 None
 1.07A 3bjwG-1y9gA:
undetectable		 3bjwG-1y9gA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2acg PROFILIN II

(Acanthamoeba
castellanii) 		PF00235
(Profilin) 		4 VAL A 112
VAL A 113
THR A   8
THR A 108
 None
 1.27A 3bjwG-2acgA:
undetectable		 3bjwG-2acgA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2btv PROTEIN (VP7 CORE
PROTEIN)

(Bluetongue
virus) 		no annotation 4 VAL P 270
THR P 321
THR P 283
ARG P 286
 None
 1.17A 3bjwG-2btvP:
undetectable		 3bjwG-2btvP:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ciy CHLOROPEROXIDASE

(Leptoxyphium
fumago) 		PF01328
(Peroxidase_2) 		4 VAL A 141
VAL A 142
THR A 250
THR A 137
 MAN  A 751 ( 4.1A)
None
MAN  A 750 (-2.0A)
None
 0.98A 3bjwG-2ciyA:
undetectable		 3bjwG-2ciyA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ddw PYRIDOXINE KINASE

(Escherichia
coli) 		PF08543
(Phos_pyr_kin) 		4 VAL A 192
VAL A 193
THR A 167
THR A 212
 None
 1.27A 3bjwG-2ddwA:
undetectable		 3bjwG-2ddwA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gqw FERREDOXIN REDUCTASE

(Pseudomonas sp.
KKS102) 		PF07992
(Pyr_redox_2)
PF14759
(Reductase_C) 		4 VAL A 106
VAL A  12
THR A 275
THR A 104
 None
 1.13A 3bjwG-2gqwA:
undetectable		 3bjwG-2gqwA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hun 336AA LONG
HYPOTHETICAL
DTDP-GLUCOSE
4,6-DEHYDRATASE

(Pyrococcus
horikoshii) 		PF16363
(GDP_Man_Dehyd) 		4 VAL A 253
VAL A 254
THR A 307
THR A 249
 None
 1.27A 3bjwG-2hunA:
undetectable		 3bjwG-2hunA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j4r EXOPOLYPHOSPHATASE

(Aquifex
aeolicus) 		PF02541
(Ppx-GppA) 		4 VAL A 207
VAL A 139
THR A 214
THR A 205
 None
 1.24A 3bjwG-2j4rA:
undetectable		 3bjwG-2j4rA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jd4 LAMININ SUBUNIT
ALPHA-1

(Mus musculus) 		PF00054
(Laminin_G_1)
PF02210
(Laminin_G_2) 		4 VAL A2785
VAL A2798
THR A2730
THR A2787
 None
 1.25A 3bjwG-2jd4A:
undetectable		 3bjwG-2jd4A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nq5 5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE

(Streptococcus
mutans) 		PF01717
(Meth_synt_2)
PF08267
(Meth_synt_1) 		4 VAL A 693
VAL A 694
THR A 417
THR A 689
 None
 1.10A 3bjwG-2nq5A:
1.2		 3bjwG-2nq5A:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pi5 DNA-DIRECTED RNA
POLYMERASE

(Escherichia
virus T7) 		PF00940
(RNA_pol)
PF14700
(RPOL_N) 		4 VAL A 137
VAL A 134
THR A 118
THR A 132
 None
 1.10A 3bjwG-2pi5A:
undetectable		 3bjwG-2pi5A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q6u NIKD PROTEIN

(Streptomyces
tendae) 		PF01266
(DAO) 		4 VAL A  97
VAL A  98
THR A 254
THR A  95
 None
 1.09A 3bjwG-2q6uA:
undetectable		 3bjwG-2q6uA:
14.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		4 VAL A   2
THR A  23
THR A  70
ARG A  72
 None
 1.17A 3bjwG-2qheA:
22.6		 3bjwG-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		4 VAL A   2
VAL A   3
THR A  23
THR A  70
 None
 0.79A 3bjwG-2qheA:
22.6		 3bjwG-2qheA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qlu ACTIVIN RECEPTOR
TYPE IIB

(Homo sapiens) 		PF00069
(Pkinase) 		4 VAL A 336
VAL A 327
THR A 265
THR A 334
 None
None
ADE  A 488 (-4.3A)
None
 1.27A 3bjwG-2qluA:
undetectable		 3bjwG-2qluA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qr3 TWO-COMPONENT SYSTEM
RESPONSE REGULATOR

(Bacteroides
fragilis) 		PF00072
(Response_reg) 		4 VAL A  48
VAL A  49
THR A 117
THR A   3
 None
 1.20A 3bjwG-2qr3A:
undetectable		 3bjwG-2qr3A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wpm COAGULATION FACTOR
IXA HEAVY CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		4 VAL S  65
VAL S  32
THR S  79
THR S  64
 None
 1.12A 3bjwG-2wpmS:
undetectable		 3bjwG-2wpmS:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x3n PROBABLE
FAD-DEPENDENT
MONOOXYGENASE

(Pseudomonas
aeruginosa) 		PF01494
(FAD_binding_3) 		4 VAL A  31
VAL A  32
THR A 121
ARG A  30
 None
 1.22A 3bjwG-2x3nA:
1.3		 3bjwG-2x3nA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xrc HUMAN COMPLEMENT
FACTOR I

(Homo sapiens) 		PF00057
(Ldl_recept_a)
PF00089
(Trypsin)
PF00530
(SRCR) 		4 VAL A 522
VAL A 436
THR A 359
THR A 520
 None
 1.24A 3bjwG-2xrcA:
undetectable		 3bjwG-2xrcA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yq4 D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE

(Lactobacillus
delbrueckii) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 VAL A  62
VAL A  61
THR A  89
THR A  36
 None
 1.25A 3bjwG-2yq4A:
undetectable		 3bjwG-2yq4A:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbc 83AA LONG
HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR ASNC

(Sulfurisphaera
tokodaii) 		PF01037
(AsnC_trans_reg) 		4 VAL A  42
VAL A  31
THR A  69
THR A  29
 None
None
ILE  A  84 (-3.6A)
None
 1.19A 3bjwG-2zbcA:
undetectable		 3bjwG-2zbcA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a1i AMIDASE

(Rhodococcus sp.
N-771) 		PF01425
(Amidase) 		4 VAL A 125
VAL A 124
THR A  83
THR A 100
 None
 1.27A 3bjwG-3a1iA:
undetectable		 3bjwG-3a1iA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b90 ENDO-PECTATE LYASE

(Dickeya
chrysanthemi) 		PF03211
(Pectate_lyase) 		4 VAL A 237
VAL A 268
THR A 242
THR A 235
 None
 1.26A 3bjwG-3b90A:
undetectable		 3bjwG-3b90A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dto BH2835 PROTEIN

(Bacillus
halodurans) 		PF01966
(HD) 		4 VAL A 118
VAL A 117
THR A  99
THR A  34
 None
 0.86A 3bjwG-3dtoA:
undetectable		 3bjwG-3dtoA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eqq BENZENE
1,2-DIOXYGENASE
SUBUNIT ALPHA

(Pseudomonas
putida) 		PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A) 		4 VAL A  81
VAL A  82
THR A 156
THR A  71
 None
 1.09A 3bjwG-3eqqA:
undetectable		 3bjwG-3eqqA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gec PERIOD CIRCADIAN
PROTEIN

(Drosophila
melanogaster) 		PF00989
(PAS)
PF14598
(PAS_11) 		4 VAL A 489
VAL A 490
THR A 439
THR A 396
 None
 1.04A 3bjwG-3gecA:
undetectable		 3bjwG-3gecA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3glg DNA POLYMERASE III
SUBUNIT DELTA'

(Escherichia
coli) 		PF09115
(DNApol3-delta_C)
PF13177
(DNA_pol3_delta2) 		4 VAL E 112
VAL E 111
THR E 131
THR E  78
 None
 1.19A 3bjwG-3glgE:
undetectable		 3bjwG-3glgE:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h09 IMMUNOGLOBULIN A1
PROTEASE

(Haemophilus
influenzae) 		PF02395
(Peptidase_S6)
PF03212
(Pertactin) 		4 VAL A 737
VAL A 736
THR A 802
THR A 712
 None
 1.27A 3bjwG-3h09A:
undetectable		 3bjwG-3h09A:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hm4 CHEMOTAXIS PROTEIN
CHEX

(Desulfovibrio
alaskensis) 		PF13690
(CheX) 		4 VAL A  49
VAL A  48
THR A  16
THR A 117
 UNL  A 156 (-4.2A)
UNL  A 156 (-4.0A)
None
None
 1.24A 3bjwG-3hm4A:
undetectable		 3bjwG-3hm4A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrd NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT

(Eubacterium
barkeri) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 VAL A 204
VAL A 192
THR A 234
THR A 202
 None
 1.11A 3bjwG-3hrdA:
undetectable		 3bjwG-3hrdA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iha SALT-TOLERANT
GLUTAMINASE

(Micrococcus
luteus) 		PF04960
(Glutaminase) 		4 VAL A 234
VAL A 233
THR A 213
THR A 238
 None
 1.25A 3bjwG-3ihaA:
undetectable		 3bjwG-3ihaA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j23 CAPSID PROTEIN VP1

(Enterovirus A) 		PF00073
(Rhv) 		4 VAL A 249
VAL A 248
THR A 237
ARG A 250
 None
 1.16A 3bjwG-3j23A:
undetectable		 3bjwG-3j23A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jsk CYPBP37 PROTEIN

(Neurospora
crassa) 		PF01946
(Thi4) 		4 VAL A 110
VAL A  85
THR A 221
THR A 108
 None
AHZ  A 500 (-4.8A)
None
None
 1.27A 3bjwG-3jskA:
0.7		 3bjwG-3jskA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kya PUTATIVE PHOSPHATASE

(Bacteroides
thetaiotaomicron) 		PF01833
(TIG) 		4 VAL A 434
VAL A 428
THR A 389
THR A 436
 None
 1.21A 3bjwG-3kyaA:
undetectable		 3bjwG-3kyaA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ldr FRUCTOSYLTRANSFERASE

(Aspergillus
japonicus) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 VAL A 594
VAL A 595
THR A 537
THR A 509
 None
 1.21A 3bjwG-3ldrA:
undetectable		 3bjwG-3ldrA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lml LIN1278 PROTEIN

(Listeria
innocua) 		PF04984
(Phage_sheath_1)
PF17481
(Phage_sheath_1N)
PF17482
(Phage_sheath_1C) 		4 VAL A 136
VAL A 124
THR A 152
THR A 138
 None
 1.27A 3bjwG-3lmlA:
undetectable		 3bjwG-3lmlA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m66 MTERF
DOMAIN-CONTAINING
PROTEIN 1,
MITOCHONDRIAL

(Homo sapiens) 		PF02536
(mTERF) 		4 VAL A 280
VAL A 281
THR A 288
THR A 276
 None
 0.93A 3bjwG-3m66A:
undetectable		 3bjwG-3m66A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mbe MHC CLASS II H2-IAG7
BETA CHAIN

(Mus musculus) 		PF00969
(MHC_II_beta)
PF07654
(C1-set) 		4 VAL B  88
THR B  21
THR B  90
ARG B  93
 None
 1.18A 3bjwG-3mbeB:
undetectable		 3bjwG-3mbeB:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mfd D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACB

(Bacillus
subtilis) 		PF00768
(Peptidase_S11)
PF07943
(PBP5_C) 		4 VAL A 232
VAL A 245
THR A  62
THR A 234
 None
 1.25A 3bjwG-3mfdA:
undetectable		 3bjwG-3mfdA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ngx BIFUNCTIONAL PROTEIN
FOLD

(Thermoplasma
acidophilum) 		PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C) 		4 VAL A 198
VAL A 199
THR A 135
THR A 154
 None
 1.24A 3bjwG-3ngxA:
undetectable		 3bjwG-3ngxA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rd5 MYPAA.01249.C

(Mycobacterium
avium) 		PF00106
(adh_short) 		4 VAL A  17
VAL A  18
THR A 233
THR A  40
 None
 1.13A 3bjwG-3rd5A:
undetectable		 3bjwG-3rd5A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3riq TAILSPIKE PROTEIN

(Salmonella
virus 9NA) 		PF09251
(PhageP22-tail) 		4 VAL A 378
VAL A 350
THR A 401
THR A 380
 None
 1.03A 3bjwG-3riqA:
undetectable		 3bjwG-3riqA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rq1 AMINOTRANSFERASE
CLASS I AND II

(Veillonella
parvula) 		PF00155
(Aminotran_1_2) 		4 VAL A 126
VAL A 179
THR A 143
THR A 128
 None
 1.15A 3bjwG-3rq1A:
undetectable		 3bjwG-3rq1A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rty PERIOD CIRCADIAN
PROTEIN

(Drosophila
melanogaster) 		PF00989
(PAS)
PF14598
(PAS_11) 		4 VAL A 489
VAL A 490
THR A 439
THR A 396
 None
 0.94A 3bjwG-3rtyA:
undetectable		 3bjwG-3rtyA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t3o METAL DEPENDENT
HYDROLASE

(Thermus
thermophilus) 		PF07521
(RMMBL)
PF12706
(Lactamase_B_2) 		4 VAL A 159
THR A  74
THR A 142
ARG A 161
 None
 1.26A 3bjwG-3t3oA:
undetectable		 3bjwG-3t3oA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t3o METAL DEPENDENT
HYDROLASE

(Thermus
thermophilus) 		PF07521
(RMMBL)
PF12706
(Lactamase_B_2) 		4 VAL A 159
VAL A 158
THR A 389
THR A 142
 None
 1.25A 3bjwG-3t3oA:
undetectable		 3bjwG-3t3oA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ug7 ARSENICAL
PUMP-DRIVING ATPASE

(Methanocaldococcus
jannaschii) 		PF02374
(ArsA_ATPase) 		4 VAL A  91
VAL A  58
THR A  40
THR A  81
 None
None
MG  A 403 ( 3.2A)
None
 1.18A 3bjwG-3ug7A:
undetectable		 3bjwG-3ug7A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zpc RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBD

(Acinetobacter
baumannii) 		PF00383
(dCMP_cyt_deam_1)
PF01872
(RibD_C) 		4 VAL A 227
VAL A 250
THR A 277
THR A 196
 None
 1.27A 3bjwG-3zpcA:
undetectable		 3bjwG-3zpcA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ah6 ASPARTATE--TRNA
LIGASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
PF02938
(GAD) 		4 VAL A 469
VAL A 468
THR A 474
THR A 465
 None
 1.21A 3bjwG-4ah6A:
undetectable		 3bjwG-4ah6A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bju N-ACETYLGLUCOSAMINE-
PHOSPHATE MUTASE

(Aspergillus
fumigatus) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I) 		4 VAL A 335
VAL A 357
THR A 388
THR A 337
 None
 1.12A 3bjwG-4bjuA:
2.4		 3bjwG-4bjuA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cgy DNA TOPOISOMERASE
3-ALPHA

(Homo sapiens) 		PF01131
(Topoisom_bac)
PF01751
(Toprim) 		4 VAL A 252
VAL A 253
THR A 554
THR A 248
 None
 1.05A 3bjwG-4cgyA:
1.0		 3bjwG-4cgyA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cp6 CHOLINE BINDING
PROTEIN PCPA

(Streptococcus
pneumoniae) 		PF13306
(LRR_5) 		4 VAL A  53
VAL A  40
THR A  99
THR A  38
 None
 1.09A 3bjwG-4cp6A:
undetectable		 3bjwG-4cp6A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dn7 ABC TRANSPORTER,
ATP-BINDING PROTEIN

(Methanosarcina
mazei) 		PF01458
(UPF0051) 		4 VAL A 222
VAL A 249
THR A 201
THR A 220
 None
 1.28A 3bjwG-4dn7A:
undetectable		 3bjwG-4dn7A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0s 5-METHYLTHIOADENOSIN
E/S-ADENOSYLHOMOCYST
EINE DEAMINASE

(Chromobacterium
violaceum) 		PF01979
(Amidohydro_1) 		4 VAL A 205
VAL A 206
THR A 188
THR A 201
 None
 0.96A 3bjwG-4f0sA:
undetectable		 3bjwG-4f0sA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g2r ACCD6,
CARBOXYLTRANSFERASE
BETA-SUBUNIT OF
ACYL-COA CARBOXYLASE

(Mycobacterium
tuberculosis) 		PF01039
(Carboxyl_trans) 		4 VAL A 114
VAL A 111
THR A 146
THR A  74
 None
 1.25A 3bjwG-4g2rA:
undetectable		 3bjwG-4g2rA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4idj FAB HEAVY CHAIN
FAB LIGHT CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 VAL H 181
VAL H 182
THR L 114
THR H 165
 None
 1.24A 3bjwG-4idjH:
undetectable		 3bjwG-4idjH:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iyo CYSTATHIONINE
GAMMA-LYASE-LIKE
PROTEIN, LYS201A
MODIFIED

(Xanthomonas
oryzae) 		PF01053
(Cys_Met_Meta_PP) 		4 VAL B 205
VAL B 204
THR B  94
THR B 187
 None
None
None
LLP  B 210 ( 3.8A)
 1.22A 3bjwG-4iyoB:
undetectable		 3bjwG-4iyoB:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4js7 CELLULOSE BINDING
PROTEIN

(Clavibacter
michiganensis) 		PF01357
(Pollen_allerg_1)
PF03330
(DPBB_1) 		4 VAL A 179
VAL A 180
THR A 109
THR A 172
 None
 1.27A 3bjwG-4js7A:
undetectable		 3bjwG-4js7A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l7v PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Vibrio cholerae) 		PF01135
(PCMT) 		4 VAL A  79
VAL A 100
THR A 148
THR A  77
 None
None
SAH  A 301 (-3.4A)
None
 1.12A 3bjwG-4l7vA:
undetectable		 3bjwG-4l7vA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4li3 CYSTEINE SYNTHASE

(Haemophilus
influenzae) 		PF00291
(PALP) 		4 VAL X 172
VAL X 173
THR X 157
THR X 198
 None
 1.16A 3bjwG-4li3X:
undetectable		 3bjwG-4li3X:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lq0 LAGLIDADG HOMING
ENDONUCLEASE

(Leptographium
truncatum) 		PF00961
(LAGLIDADG_1) 		4 VAL A  41
VAL A  29
THR A 127
THR A  43
 None
 1.27A 3bjwG-4lq0A:
undetectable		 3bjwG-4lq0A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nky STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE

(Homo sapiens) 		PF00067
(p450) 		4 VAL A 310
VAL A 311
THR A 356
THR A 306
 None
None
None
HEM  A 600 ( 3.2A)
 1.08A 3bjwG-4nkyA:
undetectable		 3bjwG-4nkyA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qdk MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE

(Synechocystis
sp. PCC 6803) 		PF07109
(Mg-por_mtran_C) 		4 VAL A  51
VAL A  52
THR A 130
THR A  47
 None
 0.97A 3bjwG-4qdkA:
undetectable		 3bjwG-4qdkA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r27 GLYCOSIDE HYDROLASE

(Microbacterium
sp. Gsoil167) 		PF00232
(Glyco_hydro_1) 		4 VAL A 122
VAL A 166
THR A  81
THR A 124
 None
 1.00A 3bjwG-4r27A:
undetectable		 3bjwG-4r27A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus T4;
Rattus
norvegicus) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 VAL A  67
VAL A  68
THR A 126
THR A  63
 None
 0.99A 3bjwG-4u16A:
undetectable		 3bjwG-4u16A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u1d EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT A

(Saccharomyces
cerevisiae) 		no annotation 4 VAL C 182
VAL C 183
THR C 158
THR C 178
 None
 1.27A 3bjwG-4u1dC:
undetectable		 3bjwG-4u1dC:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3a ENDOGLUCANASE H

(Ruminiclostridium
thermocellum) 		PF00150
(Cellulase) 		4 VAL A 239
THR A 163
THR A 236
ARG A 231
 None
 1.21A 3bjwG-4u3aA:
undetectable		 3bjwG-4u3aA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u90 GEPHYRIN

(Rattus
norvegicus) 		PF00994
(MoCF_biosynth)
PF03453
(MoeA_N)
PF03454
(MoeA_C) 		4 VAL A 639
VAL A 640
THR A 541
THR A 634
 None
 1.26A 3bjwG-4u90A:
undetectable		 3bjwG-4u90A:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uer EIF3A

(Lachancea
kluyveri) 		no annotation 4 VAL a 182
VAL a 183
THR a 158
THR a 178
 None
 1.23A 3bjwG-4uera:
undetectable		 3bjwG-4uera:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yvw CAPSID PROTEIN VP1

(Enterovirus A) 		no annotation 4 VAL E 249
VAL E 248
THR E 237
ARG E 250
 None
 1.18A 3bjwG-4yvwE:
undetectable		 3bjwG-4yvwE:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a8r METHYL-COENZYME M
REDUCTASE II SUBUNIT
GAMMA

(Methanothermobacter
marburgensis) 		PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		4 VAL B 201
VAL B 200
THR B 411
THR B 208
 None
 1.09A 3bjwG-5a8rB:
undetectable		 3bjwG-5a8rB:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bq3 RHAMNOSE ABC
TRANSPORTER,
RHAMNOSE-BINDING
PROTEIN

(Actinomyces
odontolyticus) 		PF13407
(Peripla_BP_4) 		4 VAL A 334
VAL A 335
THR A 135
THR A 327
 None
 1.18A 3bjwG-5bq3A:
undetectable		 3bjwG-5bq3A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cdi CHAPERONIN 60B1

(Chlamydomonas
reinhardtii) 		PF00118
(Cpn60_TCP1) 		4 VAL A 175
VAL A 176
THR A 325
THR A 173
 None
 1.25A 3bjwG-5cdiA:
undetectable		 3bjwG-5cdiA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dm6 50S RIBOSOMAL
PROTEIN L1

(Deinococcus
radiodurans) 		PF00687
(Ribosomal_L1) 		4 VAL 0 166
VAL 0 167
THR 0 211
THR 0 164
 C  X2178 ( 4.3A)
None
A  X2176 ( 3.8A)
C  X2179 ( 3.3A)
 1.25A 3bjwG-5dm60:
undetectable		 3bjwG-5dm60:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dmh UNCHARACTERIZED
PROTEIN CONSERVED IN
BACTERIA

(Cupriavidus
necator) 		PF07005
(DUF1537)
PF17042
(DUF1357_C) 		4 VAL A 377
VAL A 378
THR A 363
THR A 373
 None
None
None
ADP  A 501 (-3.8A)
 1.17A 3bjwG-5dmhA:
undetectable		 3bjwG-5dmhA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eog PROTEIN MAB-21-LIKE
1

(Homo sapiens) 		PF03281
(Mab-21) 		4 VAL A 167
VAL A 168
THR A 155
THR A  72
 None
 1.12A 3bjwG-5eogA:
undetectable		 3bjwG-5eogA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gq0 EPITHIOSPECIFIER
PROTEIN

(Arabidopsis
thaliana) 		no annotation 4 VAL B 199
VAL B 198
THR B 283
ARG B 184
 None
 1.22A 3bjwG-5gq0B:
undetectable		 3bjwG-5gq0B:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hj7 GLUTAMATE RACEMASE

(Mycobacterium
tuberculosis) 		PF01177
(Asp_Glu_race) 		4 VAL A 206
VAL A 182
THR A 212
THR A 204
 None
 1.28A 3bjwG-5hj7A:
undetectable		 3bjwG-5hj7A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n29 CTP SYNTHASE

(Trypanosoma
brucei) 		PF00117
(GATase) 		4 VAL A 474
VAL A 494
THR A 562
THR A 522
 None
 1.16A 3bjwG-5n29A:
undetectable		 3bjwG-5n29A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o32 COMPLEMENT FACTOR I

(Homo sapiens) 		PF00089
(Trypsin) 		4 VAL I 540
VAL I 454
THR I 377
THR I 538
 None
 1.24A 3bjwG-5o32I:
undetectable		 3bjwG-5o32I:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5odr METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
A

(Methanothermococcus
thermolithotrophicus) 		PF00374
(NiFeSe_Hases) 		4 VAL F 397
VAL F 396
THR F  57
THR F 399
 NFU  F 501 (-4.4A)
None
None
NFU  F 501 (-3.7A)
 1.18A 3bjwG-5odrF:
undetectable		 3bjwG-5odrF:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5odr METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
A
METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
G

(Methanothermococcus
thermolithotrophicus) 		PF00374
(NiFeSe_Hases)
PF01058
(Oxidored_q6) 		4 VAL F 396
VAL F 397
THR E 114
THR F 377
 None
NFU  F 501 (-4.4A)
None
None
 1.23A 3bjwG-5odrF:
undetectable		 3bjwG-5odrF:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opf CHITIN-BINDING
DOMAIN 3 PROTEIN

(Micromonospora
aurantiaca) 		no annotation 4 VAL A 208
VAL A 153
THR A 127
THR A 210
 None
 1.27A 3bjwG-5opfA:
undetectable		 3bjwG-5opfA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t5w INTERFERON LAMBDA
RECEPTOR 1

(Homo sapiens) 		PF01108
(Tissue_fac) 		4 VAL B  80
VAL B  37
THR B  11
THR B  82
 None
 1.21A 3bjwG-5t5wB:
undetectable		 3bjwG-5t5wB:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tpk PROTOCADHERIN-15

(Mus musculus) 		no annotation 4 VAL A 805
VAL A 806
THR A 815
THR A 892
 None
 1.23A 3bjwG-5tpkA:
undetectable		 3bjwG-5tpkA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vqi IMPORTIN SUBUNIT
ALPHA

(Neurospora
crassa) 		no annotation 4 VAL B 161
VAL B 162
THR B 123
THR B 157
 None
 1.22A 3bjwG-5vqiB:
undetectable		 3bjwG-5vqiB:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y0s THERMOTOGA MARITIMA
TMCAL

(Thermotoga
maritima) 		no annotation 4 VAL A  66
VAL A  67
THR A  93
THR A 343
 None
 1.22A 3bjwG-5y0sA:
undetectable		 3bjwG-5y0sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r DNA-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08163
(NUC194) 		4 VAL C1373
VAL C1371
THR C1417
THR C1375
 None
 1.27A 3bjwG-5y3rC:
undetectable		 3bjwG-5y3rC:
2.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bi4 DTDP-GLUCOSE
4,6-DEHYDRATASE

(Bacillus
anthracis) 		no annotation 4 VAL A 252
VAL A 253
THR A 306
THR A 248
 None
 1.26A 3bjwG-6bi4A:
undetectable		 3bjwG-6bi4A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gnf -

(-) 		no annotation 4 VAL A   7
VAL A  41
THR A 176
THR A   9
 None
 1.22A 3bjwG-6gnfA:
undetectable		 3bjwG-6gnfA:
undetectable