SIMILAR PATTERNS OF AMINO ACIDS FOR 3BJW_E_SVRE510_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gmz PHOSPHOLIPASE A2

(Bothrops
pirajai) 		PF00068
(Phospholip_A2_1) 		5 LYS A  15
TYR A 103
ASN A 104
LYS A 105
TYR A 107
 None
 0.81A 3bjwA-1gmzA:
19.7		 3bjwA-1gmzA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1god PROTEIN
(PHOSPHOLIPASE A2)

(Cerrophidion
godmani) 		PF00068
(Phospholip_A2_1) 		5 LYS A  16
TYR A 113
ASN A 114
TYR A 117
PRO A 121
 None
 0.97A 3bjwA-1godA:
19.9		 3bjwA-1godA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA

(Daboia russelii) 		PF00068
(Phospholip_A2_1) 		5 LYS A  16
TYR A 113
TYR A 117
PRO A 121
PHE A 124
 None
 0.88A 3bjwA-1q6vA:
21.9		 3bjwA-1q6vA:
65.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1s8h PHOSPHOLIPASE A2
HOMOLOG

(Agkistrodon
contortrix) 		PF00068
(Phospholip_A2_1) 		5 LYS A  16
TYR A 113
ASN A 114
LYS A 115
TYR A 117
 None
 0.83A 3bjwA-1s8hA:
20.4		 3bjwA-1s8hA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1vip PHOSPHOLIPASE A2

(Daboia russelii) 		PF00068
(Phospholip_A2_1) 		5 LYS A  16
TYR A 113
LYS A 115
TYR A 117
PRO A 121
 None
 0.79A 3bjwA-1vipA:
21.0		 3bjwA-1vipA:
49.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		5 LYS A  16
TYR A 113
ASN A 114
TYR A 117
PRO A 121
 None
 1.28A 3bjwA-2qheA:
22.8		 3bjwA-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		5 LYS A  16
TYR A 113
LYS A 116
TYR A 117
PRO A 121
 None
 1.42A 3bjwA-2qheA:
22.8		 3bjwA-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L

(Vipera
ammodytes) 		PF00068
(Phospholip_A2_1) 		5 LYS A  15
TYR A 103
ASN A 104
LYS A 105
TYR A 107
 None
 0.89A 3bjwA-3dihA:
22.1		 3bjwA-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1

(Bothrops
jararacussu) 		PF00068
(Phospholip_A2_1) 		5 LYS A  15
TYR A 103
ASN A 104
LYS A 105
TYR A 107
 None
None
None
None
SO4  A 203 (-4.4A)
 0.87A 3bjwA-4wtbA:
20.6		 3bjwA-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1

(Bothrops
jararacussu) 		PF00068
(Phospholip_A2_1) 		5 LYS A  15
TYR A 103
ASN A 104
TYR A 107
PHE A 114
 None
None
None
SO4  A 203 (-4.4A)
None
 0.83A 3bjwA-4wtbA:
20.6		 3bjwA-4wtbA:
56.56