SIMILAR PATTERNS OF AMINO ACIDS FOR 3BJW_A_SVRA508_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aye PROCARBOXYPEPTIDASE
A2

(Homo sapiens) 		PF00246
(Peptidase_M14)
PF02244
(Propep_M14) 		4 GLN A 285
PHE A  95
ARG A 124
ARG A 272
 None
 1.42A 3bjwE-1ayeA:
0.0		 3bjwE-1ayeA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gqj ALPHA-D-GLUCURONIDAS
E

(Cellvibrio
japonicus) 		PF03648
(Glyco_hydro_67N)
PF07477
(Glyco_hydro_67C)
PF07488
(Glyco_hydro_67M) 		4 VAL A 620
GLN A 627
PHE A 395
ARG A 660
 None
EDO  A1718 (-4.3A)
None
None
 1.45A 3bjwE-1gqjA:
0.0		 3bjwE-1gqjA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ixp PYRIDOXINE
5'-PHOSPHATE
SYNTHASE

(Escherichia
coli) 		PF03740
(PdxJ) 		4 VAL A 147
GLN A 140
PHE A 151
ARG A 117
 None
 1.45A 3bjwE-1ixpA:
0.0		 3bjwE-1ixpA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kaq NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Bacillus
subtilis) 		PF01467
(CTP_transf_like) 		4 VAL A  75
GLN A  40
PHE A   7
ARG A  95
 None
None
DND  A 601 (-4.2A)
None
 1.33A 3bjwE-1kaqA:
0.0		 3bjwE-1kaqA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kaq NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Bacillus
subtilis) 		PF01467
(CTP_transf_like) 		4 VAL A  75
GLN A  40
PHE A  36
ARG A  95
 None
 1.32A 3bjwE-1kaqA:
0.0		 3bjwE-1kaqA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ldj CULLIN HOMOLOG 1

(Homo sapiens) 		PF00888
(Cullin)
PF10557
(Cullin_Nedd8) 		4 VAL A 686
GLN A 602
PHE A 606
ARG A 681
 None
 1.41A 3bjwE-1ldjA:
0.0		 3bjwE-1ldjA:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lsh LIPOVITELLIN (LV-1N,
LV-1C)

(Ichthyomyzon
unicuspis) 		PF01347
(Vitellogenin_N)
PF09172
(DUF1943) 		4 VAL A 365
GLN A 345
PHE A 335
ARG A 379
 None
 1.45A 3bjwE-1lshA:
0.0		 3bjwE-1lshA:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus musculus) 		PF00755
(Carn_acyltransf) 		4 VAL A 114
GLN A 328
PHE A 566
ARG A 256
 None
None
152  A5001 (-3.3A)
None
 1.09A 3bjwE-1ndfA:
0.0		 3bjwE-1ndfA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2x ADP-SPECIFIC
PHOSPHOFRUCTOKINASE

(Pyrococcus
horikoshii) 		PF04587
(ADP_PFK_GK) 		4 VAL A  94
GLN A 287
PHE A 214
ARG A  81
 None
 1.44A 3bjwE-1u2xA:
0.0		 3bjwE-1u2xA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w9x ALPHA AMYLASE

(Bacillus
halmapalus) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		4 VAL A 120
GLN A 129
PHE A 173
ARG A 181
 None
 1.49A 3bjwE-1w9xA:
0.0		 3bjwE-1w9xA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y56 HYPOTHETICAL PROTEIN
PH1363

(Pyrococcus
horikoshii) 		PF07992
(Pyr_redox_2)
PF13510
(Fer2_4) 		4 VAL A 422
GLN A 411
PHE A 454
ARG A  50
 None
 1.45A 3bjwE-1y56A:
undetectable		 3bjwE-1y56A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gkw TNF
RECEPTOR-ASSOCIATED
FACTOR 3
TUMOR NECROSIS
FACTOR RECEPTOR
SUPERFAMILY MEMBER
13C

(;
Homo sapiens) 		no annotation 4 VAL B 174
GLN A 343
PHE A 381
ARG A 364
 None
 1.14A 3bjwE-2gkwB:
undetectable		 3bjwE-2gkwB:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h8l PROTEIN
DISULFIDE-ISOMERASE
A3

(Homo sapiens) 		PF13848
(Thioredoxin_6) 		4 VAL A 325
GLN A 339
PHE A 299
ARG A 304
 None
 1.40A 3bjwE-2h8lA:
undetectable		 3bjwE-2h8lA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jbw 2,6-DIHYDROXY-PSEUDO
-OXYNICOTINE
HYDROLASE

(Paenarthrobacter
nicotinovorans) 		PF06500
(DUF1100) 		4 VAL A  99
GLN A  83
PHE A 155
ARG A  91
 None
 1.38A 3bjwE-2jbwA:
undetectable		 3bjwE-2jbwA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nlk PROTEIN TYROSINE
PHOSPHATASE,
RECEPTOR TYPE, G
VARIANT (FRAGMENT)

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 VAL A1056
PHE A 994
ARG A1049
ARG A1099
 None
 1.42A 3bjwE-2nlkA:
undetectable		 3bjwE-2nlkA:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2obe HEXON

(Human
mastadenovirus
E) 		PF01065
(Adeno_hexon)
PF03678
(Adeno_hexon_C) 		4 VAL A 372
GLN A 574
ARG A 361
ARG A 311
 None
 1.32A 3bjwE-2obeA:
undetectable		 3bjwE-2obeA:
7.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x40 BETA-GLUCOSIDASE

(Thermotoga
neapolitana) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 VAL A 671
PHE A 656
ARG A 618
ARG A 622
 None
 1.29A 3bjwE-2x40A:
undetectable		 3bjwE-2x40A:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyi LIPASE, PUTATIVE

(Archaeoglobus
fulgidus) 		PF00561
(Abhydrolase_1) 		4 VAL A  25
GLN A  41
PHE A  58
ARG A  44
 None
 1.35A 3bjwE-2zyiA:
undetectable		 3bjwE-2zyiA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c4n UNCHARACTERIZED
PROTEIN DR_0571

(Deinococcus
radiodurans) 		PF01266
(DAO) 		4 VAL A 288
GLN A 281
ARG A 255
ARG A 170
 None
 1.39A 3bjwE-3c4nA:
0.7		 3bjwE-3c4nA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dhv D-ALANINE-POLY(PHOSP
HORIBITOL) LIGASE

(Bacillus cereus) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 VAL A 493
GLN A 482
PHE A 245
ARG A 495
 None
 1.32A 3bjwE-3dhvA:
undetectable		 3bjwE-3dhvA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e29 UNCHARACTERIZED
PROTEIN Q7WE92_BORBR

(Bordetella
bronchiseptica) 		PF03061
(4HBT) 		4 VAL A  35
GLN A 101
PHE A  12
ARG A  97
 None
 1.26A 3bjwE-3e29A:
undetectable		 3bjwE-3e29A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e7f 6-PHOSPHOGLUCONOLACT
ONASE

(Trypanosoma
brucei) 		PF01182
(Glucosamine_iso) 		4 VAL A 126
PHE A 105
ARG A 125
ARG A 200
 None
None
None
6PG  A 843 (-2.7A)
 1.40A 3bjwE-3e7fA:
undetectable		 3bjwE-3e7fA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gl3 PUTATIVE
THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE

(Chlorobaculum
tepidum) 		PF08534
(Redoxin) 		4 VAL A  56
GLN A  80
PHE A 136
ARG A 140
 None
 0.96A 3bjwE-3gl3A:
undetectable		 3bjwE-3gl3A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4x TRYPTOPHAN
DIMETHYLALLYLTRANSFE
RASE

(Aspergillus
fumigatus) 		PF11991
(Trp_DMAT) 		4 VAL A 211
GLN A 335
PHE A 141
ARG A 220
 None
 1.30A 3bjwE-3i4xA:
undetectable		 3bjwE-3i4xA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos taurus) 		PF00009
(GTP_EFTU)
PF11987
(IF-2) 		4 VAL P 444
GLN P 453
ARG P 382
ARG P 439
 None
 1.49A 3bjwE-3izyP:
undetectable		 3bjwE-3izyP:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kdn RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Thermococcus
kodakarensis) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 VAL A 349
GLN A 332
PHE A  29
ARG A 335
 None
 1.48A 3bjwE-3kdnA:
undetectable		 3bjwE-3kdnA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p8t ASNS-LIKE
ASPARAGINYL-TRNA
SYNTHETASE RELATED
PROTEIN

(Pyrococcus
abyssi) 		PF00152
(tRNA-synt_2) 		4 VAL A 287
PHE A 284
ARG A 103
ARG A 109
 None
 1.39A 3bjwE-3p8tA:
undetectable		 3bjwE-3p8tA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qci RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE GAMMA

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 VAL A1056
PHE A 994
ARG A1049
ARG A1099
 None
 1.45A 3bjwE-3qciA:
undetectable		 3bjwE-3qciA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u1k POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE 1, MITOCHONDRIAL

(Homo sapiens) 		PF00013
(KH_1)
PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF03726
(PNPase) 		4 VAL A 610
GLN A 641
PHE A 650
ARG A 617
 None
 1.41A 3bjwE-3u1kA:
undetectable		 3bjwE-3u1kA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bzi SEC23P

(Saccharomyces
cerevisiae) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 VAL A 300
GLN A 320
PHE A 328
ARG A 257
 None
 1.18A 3bjwE-4bziA:
undetectable		 3bjwE-4bziA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4evz HISF-LUCA

(synthetic
construct) 		PF00977
(His_biosynth) 		4 VAL A 154
PHE A 141
ARG A 158
ARG A 188
 None
 1.47A 3bjwE-4evzA:
undetectable		 3bjwE-4evzA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f2e CUPA

(Streptococcus
pneumoniae) 		PF13473
(Cupredoxin_1) 		4 VAL A  65
PHE A  83
ARG A  42
ARG A  68
 None
 1.45A 3bjwE-4f2eA:
undetectable		 3bjwE-4f2eA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f6a BH1408 PROTEIN

(Bacillus
halodurans) 		PF00583
(Acetyltransf_1) 		4 VAL A  58
PHE A 110
ARG A   4
ARG A  16
 None
 1.05A 3bjwE-4f6aA:
undetectable		 3bjwE-4f6aA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f7k LACCASE

(uncultured
bacterium) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 400
GLN A 253
PHE A 371
ARG A 395
 None
 1.32A 3bjwE-4f7kA:
undetectable		 3bjwE-4f7kA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gi2 CROTONYL-COA
CARBOXYLASE/REDUCTAS
E

(Methylobacterium
extorquens) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 VAL A 128
GLN A 170
PHE A 166
ARG A 172
 None
 1.46A 3bjwE-4gi2A:
undetectable		 3bjwE-4gi2A:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h2h MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Salipiger
bermudensis) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 VAL A 139
GLN A 148
ARG A 167
ARG A 147
 None
 1.41A 3bjwE-4h2hA:
undetectable		 3bjwE-4h2hA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igl YENB

(Yersinia
entomophaga) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN) 		4 VAL A 268
GLN A 210
PHE A 265
ARG A 274
 None
 1.34A 3bjwE-4iglA:
undetectable		 3bjwE-4iglA:
5.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nc6 RAB
GTPASE-ACTIVATING
PROTEIN 1

(Homo sapiens) 		PF00566
(RabGAP-TBC) 		4 VAL A 589
GLN A 577
PHE A 676
ARG A 593
 None
 1.39A 3bjwE-4nc6A:
undetectable		 3bjwE-4nc6A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o26 TELOMERASE REVERSE
TRANSCRIPTASE

(Oryzias latipes) 		PF12009
(Telomerase_RBD) 		4 VAL A 350
GLN A 510
PHE A 519
ARG A 506
 None
None
None
U  E 182 ( 4.0A)
 1.33A 3bjwE-4o26A:
undetectable		 3bjwE-4o26A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p7y METHIONINE
GAMMA-LYASE

(Citrobacter
freundii) 		PF01053
(Cys_Met_Meta_PP) 		4 VAL A 204
GLN A 195
PHE A 188
ARG A  78
 None
1PE  A 402 (-4.0A)
None
None
 1.43A 3bjwE-4p7yA:
undetectable		 3bjwE-4p7yA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uw2 CSM1

(Thermococcus
onnurineus) 		PF01966
(HD) 		4 GLN A 481
PHE A 296
ARG A 214
ARG A 171
 None
 1.33A 3bjwE-4uw2A:
undetectable		 3bjwE-4uw2A:
8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y0e PUTATIVE DIOXYGENASE

(Mycobacteroides
abscessus) 		PF02668
(TauD) 		4 VAL A 284
GLN A 294
PHE A 109
ARG A 291
 None
 1.36A 3bjwE-4y0eA:
undetectable		 3bjwE-4y0eA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysb METALLO-BETA-LACTAMA
SE FAMILY PROTEIN

(Myxococcus
xanthus) 		PF00753
(Lactamase_B) 		4 VAL A  77
PHE A 104
ARG A  70
ARG A 221
 None
 1.32A 3bjwE-4ysbA:
undetectable		 3bjwE-4ysbA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e66 HEMAGGLUTININ-ESTERA
SE

(Influenza D
virus) 		PF02710
(Hema_HEFG)
PF03996
(Hema_esterase) 		4 VAL A 116
PHE A 138
ARG A  58
ARG A 327
 CAC  A 501 (-4.7A)
None
None
None
 1.49A 3bjwE-5e66A:
undetectable		 3bjwE-5e66A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5efv PHI ETA ORF 56-LIKE
PROTEIN

(Staphylococcus
virus 11) 		no annotation 4 VAL A 426
GLN A 148
PHE A 152
ARG A 142
 None
 0.93A 3bjwE-5efvA:
undetectable		 3bjwE-5efvA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fp1 TONB-DEPENDENT
SIDEROPHORE RECEPTOR

(Acinetobacter
baumannii) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 VAL A  54
GLN A 678
PHE A 109
ARG A  62
 None
 1.34A 3bjwE-5fp1A:
undetectable		 3bjwE-5fp1A:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxu DYP-TYPE PEROXIDASE
FAMILY

(Thermomonospora
curvata) 		PF04261
(Dyp_perox) 		4 VAL A 252
GLN A 196
PHE A 125
ARG A 255
 None
 1.46A 3bjwE-5jxuA:
undetectable		 3bjwE-5jxuA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kqi CATALASE-PEROXIDASE

(Burkholderia
pseudomallei) 		PF00141
(peroxidase) 		4 VAL A 652
PHE A 601
ARG A 649
ARG A 656
 None
None
None
MPD  A 808 ( 4.0A)
 1.30A 3bjwE-5kqiA:
undetectable		 3bjwE-5kqiA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldn HEXON PROTEIN,HEXON
CAPSID

(Human
mastadenovirus
C) 		PF01065
(Adeno_hexon)
PF03678
(Adeno_hexon_C) 		4 VAL A 390
GLN A 593
ARG A 379
ARG A 329
 None
 1.32A 3bjwE-5ldnA:
undetectable		 3bjwE-5ldnA:
8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5my0 FATTY ACID SYNTHASE

(Mus musculus) 		no annotation 4 VAL B 527
GLN B 596
PHE B 553
ARG B 522
 None
 1.30A 3bjwE-5my0B:
undetectable		 3bjwE-5my0B:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nfb GALECTIN-3

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 VAL A 172
PHE A 149
ARG A 186
ARG A 169
 None
None
8VT  A 301 (-3.4A)
None
 1.43A 3bjwE-5nfbA:
undetectable		 3bjwE-5nfbA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5owj TRIGGER FACTOR

(Escherichia
coli) 		no annotation 4 VAL A 258
GLN A 191
PHE A 252
ARG A 193
 None
 1.27A 3bjwE-5owjA:
undetectable		 3bjwE-5owjA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7c ACYLOXYACYL
HYDROLASE

(Homo sapiens) 		no annotation 4 VAL C 180
GLN C 335
PHE C 193
ARG C 356
 None
 1.29A 3bjwE-5w7cC:
undetectable		 3bjwE-5w7cC:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bka NITRONATE
MONOOXYGENASE

(Cyberlindnera
mrakii) 		no annotation 4 VAL A 168
GLN A 190
PHE A 234
ARG A 198
 None
FMN  A 401 (-3.9A)
None
None
 1.46A 3bjwE-6bkaA:
undetectable		 3bjwE-6bkaA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6egx STRUCTURAL PROTEIN
VP1
STRUCTURAL PROTEIN
VP2

(Sacbrood virus) 		no annotation 4 VAL A 176
GLN B 138
PHE B 134
ARG A 184
 None
 1.38A 3bjwE-6egxA:
undetectable		 3bjwE-6egxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fof GALECTIN-3,GALECTIN-
3

(Homo sapiens) 		no annotation 4 VAL C 172
PHE C 149
ARG C 186
ARG C 169
 None
None
LAT  C 301 (-4.0A)
None
 1.38A 3bjwE-6fofC:
undetectable		 3bjwE-6fofC:
undetectable