SIMILAR PATTERNS OF AMINO ACIDS FOR 3BGD_B_PM6B301

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ad3 ALDEHYDE
DEHYDROGENASE (CLASS
3)

(Rattus
norvegicus) 		PF00171
(Aldedh) 		4 PHE A 335
GLY A 336
VAL A 338
LEU A 296
 NAD  A 600 (-3.8A)
None
None
None
 1.13A 3bgdB-1ad3A:
4.2		 3bgdB-1ad3A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE

(Pagrus major) 		PF00868
(Transglut_N)
PF00927
(Transglut_C)
PF01841
(Transglut_core) 		4 PHE A 134
VAL A 155
LEU A 151
PRO A 289
 None
 0.83A 3bgdB-1g0dA:
undetectable		 3bgdB-1g0dA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itz TRANSKETOLASE

(Zea mays) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 GLY A 262
VAL A 274
LEU A 279
PRO A  39
 None
 0.96A 3bgdB-1itzA:
undetectable		 3bgdB-1itzA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT

(Galdieria
partita) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 GLY A 395
VAL A 398
LEU A 400
PRO A 168
 None
 0.98A 3bgdB-1iwaA:
undetectable		 3bgdB-1iwaA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nvt SHIKIMATE
5'-DEHYDROGENASE

(Methanocaldococcus
jannaschii) 		PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N) 		4 GLY A  18
VAL A  48
LEU A  53
PRO A  50
 None
 1.10A 3bgdB-1nvtA:
5.4		 3bgdB-1nvtA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o70 FASCICLIN I

(Drosophila
melanogaster) 		PF02469
(Fasciclin) 		4 PHE A 419
GLY A 437
VAL A 435
LEU A 360
 None
 1.10A 3bgdB-1o70A:
undetectable		 3bgdB-1o70A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qnl ALIPHATIC AMIDASE
EXPRESSION-REGULATIN
G PROTEIN

(Pseudomonas
aeruginosa) 		PF13433
(Peripla_BP_5) 		4 PHE A 145
GLY A 147
VAL A 205
LEU A 213
 None
 0.86A 3bgdB-1qnlA:
2.3		 3bgdB-1qnlA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r62 NITROGEN REGULATION
PROTEIN NR(II)

(Escherichia
coli) 		PF02518
(HATPase_c) 		4 GLY A 257
VAL A 218
LEU A 250
PRO A 215
 None
 1.12A 3bgdB-1r62A:
undetectable		 3bgdB-1r62A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t5e MULTIDRUG RESISTANCE
PROTEIN MEXA

(Pseudomonas
aeruginosa) 		PF00529
(HlyD)
PF16576
(HlyD_D23) 		4 PHE A 254
GLY A  33
VAL A 175
LEU A 208
 None
 0.89A 3bgdB-1t5eA:
undetectable		 3bgdB-1t5eA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w07 ACYL-COA OXIDASE

(Arabidopsis
thaliana) 		PF01756
(ACOX)
PF02770
(Acyl-CoA_dh_M)
PF14749
(Acyl-CoA_ox_N) 		4 PHE A 346
GLY A 348
VAL A 289
LEU A 380
 None
 0.78A 3bgdB-1w07A:
undetectable		 3bgdB-1w07A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN

(Escherichia
coli) 		PF04257
(Exonuc_V_gamma) 		4 ARG C 734
GLY C 733
VAL C 378
LEU C 783
 None
 1.04A 3bgdB-1w36C:
2.5		 3bgdB-1w36C:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z6g GUANYLATE KINASE

(Plasmodium
falciparum) 		PF00625
(Guanylate_kin) 		4 GLY A  11
VAL A  15
LEU A 132
PRO A 126
 None
SO4  A 400 (-4.1A)
None
None
 1.03A 3bgdB-1z6gA:
undetectable		 3bgdB-1z6gA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a7m N-ACYL HOMOSERINE
LACTONE HYDROLASE

(Bacillus
thuringiensis) 		PF00753
(Lactamase_B) 		4 PHE A 177
GLY A 160
VAL A   3
LEU A  40
 None
 0.88A 3bgdB-2a7mA:
undetectable		 3bgdB-2a7mA:
22.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2bzg THIOPURINE
S-METHYLTRANSFERASE

(Homo sapiens) 		PF05724
(TPMT) 		6 PHE A  40
ARG A 152
GLY A 153
VAL A 156
LEU A 185
PRO A 196
 SAH  A1246 (-3.4A)
SAH  A1246 (-4.0A)
SAH  A1246 (-3.9A)
None
None
None
 0.35A 3bgdB-2bzgA:
39.3		 3bgdB-2bzgA:
71.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2bzg THIOPURINE
S-METHYLTRANSFERASE

(Homo sapiens) 		PF05724
(TPMT) 		6 PHE A  40
GLY A 153
VAL A 156
LEU A 185
PRO A 196
ARG A 226
 SAH  A1246 (-3.4A)
SAH  A1246 (-3.9A)
None
None
None
None
 0.62A 3bgdB-2bzgA:
39.3		 3bgdB-2bzgA:
71.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2bzg THIOPURINE
S-METHYLTRANSFERASE

(Homo sapiens) 		PF05724
(TPMT) 		5 PHE A  40
VAL A 156
PRO A 196
ARG A 226
TRP A 230
 SAH  A1246 (-3.4A)
None
None
None
None
 0.78A 3bgdB-2bzgA:
39.3		 3bgdB-2bzgA:
71.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ddh ACYL-COA OXIDASE

(Rattus
norvegicus) 		PF01756
(ACOX)
PF02770
(Acyl-CoA_dh_M)
PF14749
(Acyl-CoA_ox_N) 		4 PHE A 343
GLY A 345
VAL A 286
LEU A 377
 None
 0.82A 3bgdB-2ddhA:
undetectable		 3bgdB-2ddhA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dv6 NITRITE REDUCTASE

(Hyphomicrobium
denitrificans) 		PF07732
(Cu-oxidase_3) 		4 GLY A 254
VAL A 380
LEU A 285
PRO A 281
 None
 1.14A 3bgdB-2dv6A:
undetectable		 3bgdB-2dv6A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dv6 NITRITE REDUCTASE

(Hyphomicrobium
denitrificans) 		PF07732
(Cu-oxidase_3) 		4 PHE A 196
GLY A 275
LEU A 168
PRO A 195
 None
 1.13A 3bgdB-2dv6A:
undetectable		 3bgdB-2dv6A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ecr FLAVIN REDUCTASE
COMPONENT (HPAC) OF
4-HYDROXYPHENYLACETA
TE 3-MONOOXYGENASE

(Thermus
thermophilus) 		PF01613
(Flavin_Reduct) 		4 GLY A  15
VAL A 136
LEU A 145
PRO A 134
 None
 0.99A 3bgdB-2ecrA:
undetectable		 3bgdB-2ecrA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f1m ACRIFLAVINE
RESISTANCE PROTEIN A

(Escherichia
coli) 		PF16576
(HlyD_D23) 		4 PHE A 292
GLY A  58
VAL A 214
LEU A 246
 None
 1.13A 3bgdB-2f1mA:
undetectable		 3bgdB-2f1mA:
21.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gb4 THIOPURINE
S-METHYLTRANSFERASE

(Mus musculus) 		PF05724
(TPMT) 		4 ARG A 147
GLY A 148
VAL A 151
ARG A 221
 SAH  A 300 (-3.9A)
SAH  A 300 (-3.9A)
None
None
 1.03A 3bgdB-2gb4A:
42.0		 3bgdB-2gb4A:
95.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gb4 THIOPURINE
S-METHYLTRANSFERASE

(Mus musculus) 		PF05724
(TPMT) 		7 PHE A  35
ARG A 147
GLY A 148
VAL A 151
LEU A 180
PRO A 191
TRP A 225
 SAH  A 300 (-3.4A)
SAH  A 300 (-3.9A)
SAH  A 300 (-3.9A)
None
None
None
None
 0.41A 3bgdB-2gb4A:
42.0		 3bgdB-2gb4A:
95.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gwc GLUTAMATE CYSTEINE
LIGASE

(Brassica juncea) 		PF04107
(GCS2) 		4 PHE A 275
GLY A 391
LEU A 512
PRO A 393
 None
 1.02A 3bgdB-2gwcA:
undetectable		 3bgdB-2gwcA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hae MALATE
OXIDOREDUCTASE

(Thermotoga
maritima) 		PF00390
(malic)
PF03949
(Malic_M) 		4 PHE A 318
GLY A 158
VAL A 161
LEU A 337
 None
 0.79A 3bgdB-2haeA:
5.4		 3bgdB-2haeA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jg2 SERINE
PALMITOYLTRANSFERASE

(Sphingomonas
paucimobilis) 		PF00155
(Aminotran_1_2) 		4 ARG A 120
GLY A 127
VAL A 275
ARG A 103
 None
 0.86A 3bgdB-2jg2A:
2.2		 3bgdB-2jg2A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ly3 TRANSLOCATION AND
ASSEMBLY MODULE TAMA

(Escherichia
coli) 		PF17243
(POTRA_TamA_1) 		4 GLY 1  30
VAL 1  98
LEU 1  69
PRO 1 100
 None
 0.93A 3bgdB-2ly31:
undetectable		 3bgdB-2ly31:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p76 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE

(Staphylococcus
aureus) 		PF03009
(GDPD) 		4 PHE A 297
GLY A 295
VAL A 293
LEU A 288
 GOL  A 501 (-4.2A)
None
None
None
 1.11A 3bgdB-2p76A:
undetectable		 3bgdB-2p76A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ppt THIOREDOXIN-2

(Rhodobacter
capsulatus) 		PF00085
(Thioredoxin) 		4 PHE A 122
VAL A  94
LEU A 148
PRO A  63
 None
 1.10A 3bgdB-2pptA:
undetectable		 3bgdB-2pptA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q7r ARACHIDONATE
5-LIPOXYGENASE-ACTIV
ATING PROTEIN

(Homo sapiens) 		PF01124
(MAPEG) 		4 PHE A  85
GLY A  87
VAL A  15
LEU A  12
 None
 0.86A 3bgdB-2q7rA:
undetectable		 3bgdB-2q7rA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r62 CELL DIVISION
PROTEASE FTSH
HOMOLOG

(Helicobacter
pylori) 		PF00004
(AAA) 		4 PHE A 344
GLY A 375
LEU A 381
PRO A 342
 None
 1.10A 3bgdB-2r62A:
2.1		 3bgdB-2r62A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsb HYALURONOGLUCOSAMINI
DASE

(Oceanicola
granulosus) 		PF07555
(NAGidase) 		4 PHE A 189
VAL A 248
LEU A 205
PRO A 216
 None
 0.77A 3bgdB-2xsbA:
undetectable		 3bgdB-2xsbA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ych COMPETENCE PROTEIN
PILM

(Thermus
thermophilus) 		PF11104
(PilM_2) 		4 PHE A 193
GLY A 310
VAL A 332
PRO A 307
 None
 0.81A 3bgdB-2ychA:
undetectable		 3bgdB-2ychA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9y AMMONIUM TRANSPORTER
FAMILY RH-LIKE
PROTEIN

(Nitrosomonas
europaea) 		PF00909
(Ammonium_transp) 		4 GLY A 270
VAL A 272
LEU A 323
PRO A 327
 None
 1.01A 3bgdB-3b9yA:
undetectable		 3bgdB-3b9yA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo sapiens) 		PF04042
(DNA_pol_E_B) 		4 PHE A 341
VAL A 423
LEU A 369
PRO A 399
 None
 1.14A 3bgdB-3e0jA:
undetectable		 3bgdB-3e0jA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eeg 2-ISOPROPYLMALATE
SYNTHASE

(Cytophaga
hutchinsonii) 		PF00682
(HMGL-like) 		4 PHE A  47
GLY A  46
VAL A  58
LEU A  88
 None
 1.15A 3bgdB-3eegA:
undetectable		 3bgdB-3eegA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ewm UNCHARACTERIZED
SUGAR KINASE PH1459

(Pyrococcus
horikoshii) 		PF00294
(PfkB) 		4 PHE A  61
GLY A  62
VAL A  56
LEU A  10
 None
 0.93A 3bgdB-3ewmA:
3.7		 3bgdB-3ewmA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f65 CHAPERONE PROTEIN
FAEE

(Escherichia
coli) 		PF00345
(PapD_N) 		4 PHE A  55
VAL A  51
LEU A  66
PRO A  53
 None
 1.06A 3bgdB-3f65A:
undetectable		 3bgdB-3f65A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fdg DIPEPTIDASE AC.
METALLO PEPTIDASE.
MEROPS FAMILY M19

(Rhodobacter
sphaeroides) 		PF01244
(Peptidase_M19) 		4 GLY A 171
VAL A 163
LEU A 211
PRO A 162
 None
 0.89A 3bgdB-3fdgA:
undetectable		 3bgdB-3fdgA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hd6 AMMONIUM TRANSPORTER
RH TYPE C

(Homo sapiens) 		PF00909
(Ammonium_transp) 		4 GLY A 289
VAL A 291
LEU A 343
PRO A 347
 None
 1.03A 3bgdB-3hd6A:
undetectable		 3bgdB-3hd6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hje 704AA LONG
HYPOTHETICAL
GLYCOSYLTRANSFERASE

(Sulfurisphaera
tokodaii) 		PF00128
(Alpha-amylase)
PF09196
(DUF1953) 		4 PHE A 493
GLY A 491
VAL A 448
LEU A 591
 None
 1.05A 3bgdB-3hjeA:
undetectable		 3bgdB-3hjeA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6y ESTERASE APC40077

(Oleispira
antarctica) 		PF00756
(Esterase) 		4 PHE A 171
GLY A 146
LEU A 155
PRO A 173
 None
 1.15A 3bgdB-3i6yA:
undetectable		 3bgdB-3i6yA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k6k ESTERASE/LIPASE

(uncultured
bacterium) 		PF07859
(Abhydrolase_3) 		4 GLY A 161
VAL A 188
LEU A 260
PRO A 186
 None
 0.91A 3bgdB-3k6kA:
2.5		 3bgdB-3k6kA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kom TRANSKETOLASE

(Francisella
tularensis) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 GLY A 250
VAL A 262
LEU A 267
PRO A  29
 None
 0.93A 3bgdB-3komA:
undetectable		 3bgdB-3komA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE

(Methylobacillus
flagellatus) 		PF14403
(CP_ATPgrasp_2) 		4 GLY A 145
LEU A 148
PRO A 430
TRP A  83
 None
None
None
GOL  A 488 (-3.9A)
 0.96A 3bgdB-3n6xA:
undetectable		 3bgdB-3n6xA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3prl NADP-DEPENDENT
GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Bacillus
halodurans) 		PF00171
(Aldedh) 		4 PHE A 388
GLY A 389
VAL A 391
LEU A 346
 None
 1.06A 3bgdB-3prlA:
3.1		 3bgdB-3prlA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pua PHD FINGER PROTEIN 2

(Homo sapiens) 		PF02373
(JmjC) 		4 PHE A 314
VAL A 105
LEU A 270
PRO A 126
 None
 0.81A 3bgdB-3puaA:
undetectable		 3bgdB-3puaA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q5t TCR N30 BETA

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY A 212
VAL A 120
PRO A 152
ARG A 110
 None
 1.05A 3bgdB-3q5tA:
undetectable		 3bgdB-3q5tA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6h N-ACETYLGLUTAMATE
KINASE /
N-ACETYLGLUTAMATE
SYNTHASE

(Maricaulis
maris) 		PF00696
(AA_kinase)
PF04768
(NAT) 		4 PHE A 139
ARG A 136
GLY A 179
VAL A 187
 None
 1.15A 3bgdB-3s6hA:
undetectable		 3bgdB-3s6hA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sbq NITROUS-OXIDE
REDUCTASE

(Pseudomonas
stutzeri) 		no annotation 4 ARG A 114
GLY A 108
VAL A 101
LEU A 124
 None
 1.04A 3bgdB-3sbqA:
undetectable		 3bgdB-3sbqA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u1k POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE 1, MITOCHONDRIAL

(Homo sapiens) 		PF00013
(KH_1)
PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF03726
(PNPase) 		4 GLY A 161
VAL A 159
PRO A 165
ARG A 192
 None
 1.14A 3bgdB-3u1kA:
undetectable		 3bgdB-3u1kA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wvi TYPE-2 RESTRICTION
ENZYME HINDIII

(Haemophilus
influenzae) 		PF09518
(RE_HindIII) 		4 GLY A  67
VAL A  70
LEU A  42
ARG A 244
 None
 1.15A 3bgdB-3wviA:
undetectable		 3bgdB-3wviA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bju N-ACETYLGLUCOSAMINE-
PHOSPHATE MUTASE

(Aspergillus
fumigatus) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I) 		4 PHE A  32
GLY A  77
VAL A  66
LEU A 141
 None
 1.06A 3bgdB-4bjuA:
undetectable		 3bgdB-4bjuA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c7w HEMAGGLUTININ-ESTERA
SE

(Murine
coronavirus) 		PF02710
(Hema_HEFG)
PF03996
(Hema_esterase) 		4 PHE A  42
GLY A  43
LEU A 353
TRP A  39
 None
 1.04A 3bgdB-4c7wA:
undetectable		 3bgdB-4c7wA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cmw DITERPENE SYNTHASE

(Mycobacterium
tuberculosis) 		no annotation 4 GLY A  70
VAL A  21
LEU A 244
PRO A  26
 None
 0.70A 3bgdB-4cmwA:
2.3		 3bgdB-4cmwA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cza NA+/H+ ANTIPORTER,
PUTATIVE

(Pyrococcus
abyssi) 		PF00999
(Na_H_Exchanger) 		4 PHE A 245
GLY A 247
VAL A 257
LEU A 213
 None
 0.96A 3bgdB-4czaA:
undetectable		 3bgdB-4czaA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cza NA+/H+ ANTIPORTER,
PUTATIVE

(Pyrococcus
abyssi) 		PF00999
(Na_H_Exchanger) 		4 PHE A 245
GLY A 254
VAL A 257
LEU A 209
 None
 0.82A 3bgdB-4czaA:
undetectable		 3bgdB-4czaA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4di1 ENOYL-COA HYDRATASE
ECHA17

(Mycobacterium
marinum) 		PF00378
(ECH_1) 		4 GLY A  48
LEU A 204
PRO A  96
TRP A 118
 None
 0.84A 3bgdB-4di1A:
undetectable		 3bgdB-4di1A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eae LMO1068 PROTEIN

(Listeria
monocytogenes) 		PF16781
(DUF5068) 		4 GLY A 173
VAL A 152
LEU A 118
PRO A 155
 None
 0.81A 3bgdB-4eaeA:
undetectable		 3bgdB-4eaeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4egc MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HOMEOBOX PROTEIN
SIX1 CHIMERA

(Escherichia
coli;
Homo sapiens) 		PF00046
(Homeobox)
PF13416
(SBP_bac_8)
PF16878
(SIX1_SD) 		4 PHE A 258
GLY A 327
LEU A 247
PRO A 159
 None
 1.11A 3bgdB-4egcA:
undetectable		 3bgdB-4egcA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ej0 ADP-L-GLYCERO-D-MANN
O-HEPTOSE-6-EPIMERAS
E

(Burkholderia
thailandensis) 		PF01370
(Epimerase) 		4 PHE A  11
GLY A  13
VAL A  17
LEU A  43
 NAP  A 401 (-4.8A)
None
None
None
 1.04A 3bgdB-4ej0A:
4.6		 3bgdB-4ej0A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fcs VERSATILE PEROXIDASE
VPL2

(Pleurotus
eryngii) 		PF00141
(peroxidase)
PF11895
(Peroxidase_ext) 		4 PHE A 123
VAL A 281
LEU A  17
ARG A 126
 None
 1.03A 3bgdB-4fcsA:
undetectable		 3bgdB-4fcsA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hea NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 13

(Thermus
thermophilus) 		PF00361
(Proton_antipo_M) 		4 PHE M 110
GLY M 108
VAL M   6
ARG M 243
 None
 1.05A 3bgdB-4heaM:
undetectable		 3bgdB-4heaM:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hea NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 13
NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 14

(Thermus
thermophilus) 		PF00361
(Proton_antipo_M) 		4 PHE N 383
ARG N 317
GLY N 314
ARG M 141
 None
 1.12A 3bgdB-4heaN:
undetectable		 3bgdB-4heaN:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i7u DIHYDRODIPICOLINATE
SYNTHASE

(Agrobacterium
sp. H13-3) 		PF00701
(DHDPS) 		4 GLY A 252
LEU A 271
PRO A 248
ARG A 138
 None
 1.13A 3bgdB-4i7uA:
undetectable		 3bgdB-4i7uA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jso OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF00496
(SBP_bac_5) 		4 PHE A 258
GLY A 302
LEU A 313
PRO A 260
 None
 1.11A 3bgdB-4jsoA:
undetectable		 3bgdB-4jsoA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jxk OXIDOREDUCTASE

(Rhodococcus
opacus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 GLY A 130
VAL A 164
LEU A 295
PRO A 292
 None
 0.98A 3bgdB-4jxkA:
5.5		 3bgdB-4jxkA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4llr TRYPAREDOXIN
PEROXIDASE

(Trypanosoma
cruzi) 		PF00578
(AhpC-TSA)
PF10417
(1-cysPrx_C) 		4 PHE A  43
VAL A 125
PRO A  45
ARG A 151
 None
 1.11A 3bgdB-4llrA:
undetectable		 3bgdB-4llrA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m1e PURINE NUCLEOSIDE
PHOSPHORYLASE

(Planctopirus
limnophila) 		PF01048
(PNP_UDP_1) 		4 GLY A  26
VAL A 106
PRO A  23
TRP A  19
 None
 1.01A 3bgdB-4m1eA:
undetectable		 3bgdB-4m1eA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pqk MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
TRUNCATED
REPLICATION PROTEIN
REPA

(Escherichia
coli;
Staphylococcus
aureus) 		PF13416
(SBP_bac_8) 		4 PHE A 259
GLY A 328
LEU A 248
PRO A 160
 None
 1.05A 3bgdB-4pqkA:
undetectable		 3bgdB-4pqkA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qhr ALANINE RACEMASE

(Acinetobacter
baumannii) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 PHE A  55
GLY A  56
LEU A  77
ARG A  67
 None
 1.14A 3bgdB-4qhrA:
undetectable		 3bgdB-4qhrA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rcd BETA-SECRETASE 1

(Homo sapiens) 		PF00026
(Asp) 		4 GLY A 177
VAL A 146
LEU A 140
PRO A  91
 None
 1.15A 3bgdB-4rcdA:
undetectable		 3bgdB-4rcdA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3p 4-ALPHA-GLUCANOTRANS
FERASE

(Escherichia
coli) 		PF02446
(Glyco_hydro_77) 		4 GLY A  94
VAL A  70
LEU A 113
PRO A  53
 None
 1.12A 3bgdB-4s3pA:
undetectable		 3bgdB-4s3pA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ulx LPBCA-L89K
THIOREDOXIN

(synthetic
construct) 		PF00085
(Thioredoxin) 		4 PHE A  80
VAL A  52
LEU A 106
PRO A  21
 None
 0.99A 3bgdB-4ulxA:
undetectable		 3bgdB-4ulxA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wec SHORT CHAIN
DEHYDROGENASE

(Mycolicibacterium
smegmatis) 		PF13561
(adh_short_C2) 		4 PHE A  86
GLY A  17
VAL A  38
LEU A  53
 None
NAD  A 301 ( 4.8A)
None
None
 0.99A 3bgdB-4wecA:
6.2		 3bgdB-4wecA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wr3 ALANINE RACEMASE,
BIOSYNTHETIC

(Escherichia
coli) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 PHE A  55
GLY A  56
LEU A  77
ARG A  67
 None
 1.08A 3bgdB-4wr3A:
undetectable		 3bgdB-4wr3A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgj UNCHARACTERIZED
PROTEIN

(Pectobacterium
atrosepticum) 		PF07005
(DUF1537)
PF17042
(DUF1357_C) 		4 VAL A 114
LEU A 116
PRO A 222
TRP A  86
 None
 0.74A 3bgdB-4xgjA:
2.8		 3bgdB-4xgjA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans) 		PF00072
(Response_reg) 		4 GLY A  46
VAL A  79
LEU A  75
PRO A  76
 None
 1.13A 3bgdB-4xltA:
2.4		 3bgdB-4xltA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c08 1E6 TCR BETA CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY E 218
VAL E 122
LEU E 116
PRO E 154
 None
 1.10A 3bgdB-5c08E:
undetectable		 3bgdB-5c08E:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ey7 FRUCTOKINASE

(Vibrio cholerae) 		PF00294
(PfkB) 		4 PHE A  75
GLY A  73
VAL A  67
LEU A  90
 None
 1.10A 3bgdB-5ey7A:
3.4		 3bgdB-5ey7A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gxf ACRYLYL-COA
REDUCTASE ACUI

(Ruegeria
pomeroyi) 		PF00107
(ADH_zinc_N) 		4 PHE A 132
GLY A 131
VAL A 165
LEU A 296
 None
 1.11A 3bgdB-5gxfA:
5.0		 3bgdB-5gxfA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h3b UNCHARACTERIZED
PROTEIN HI_1552

(Haemophilus
influenzae) 		PF04301
(DUF452) 		4 GLY A  67
VAL A  70
LEU A 151
ARG A 139
 None
 1.05A 3bgdB-5h3bA:
undetectable		 3bgdB-5h3bA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i51 TRANSKETOLASE

(Scheffersomyces
stipitis) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 GLY A 249
VAL A 260
LEU A 265
PRO A  28
 None
 1.04A 3bgdB-5i51A:
undetectable		 3bgdB-5i51A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jry NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans) 		PF00171
(Aldedh) 		4 GLY A 410
VAL A 431
LEU A 426
ARG A 290
 None
 1.14A 3bgdB-5jryA:
3.5		 3bgdB-5jryA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k13 RETINOIC ACID
RECEPTOR ALPHA

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 PHE A 249
VAL A 191
LEU A 187
PRO A 247
 None
 1.14A 3bgdB-5k13A:
undetectable		 3bgdB-5k13A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ls0 SOLUBLE INORGANIC
PYROPHOSPHATASE 1

(Arabidopsis
thaliana) 		PF00719
(Pyrophosphatase) 		4 PHE A  49
VAL A  52
LEU A  39
PRO A  92
 None
 1.02A 3bgdB-5ls0A:
undetectable		 3bgdB-5ls0A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n28 METHYL-COENZYME M
REDUCTASE, GAMMA
SUBUNIT

(Methanotorris
formicicus) 		PF02240
(MCR_gamma) 		4 ARG C 129
GLY C  78
LEU C  59
PRO C  75
 None
 1.13A 3bgdB-5n28C:
undetectable		 3bgdB-5n28C:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5txf PHOSPHATIDYLCHOLINE-
STEROL
ACYLTRANSFERASE

(Homo sapiens) 		no annotation 4 GLY A 205
VAL A 309
LEU A 191
TRP A 198
 None
 0.92A 3bgdB-5txfA:
undetectable		 3bgdB-5txfA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uoh CARBOXYLESTERASE A

(Mycobacterium
tuberculosis) 		PF00561
(Abhydrolase_1) 		4 PHE A  94
GLY A 138
VAL A 105
LEU A 217
 None
 1.05A 3bgdB-5uohA:
undetectable		 3bgdB-5uohA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense) 		PF00171
(Aldedh)
PF01619
(Pro_dh) 		4 GLY A 802
VAL A 822
LEU A 776
PRO A 821
 None
 1.01A 3bgdB-5ux5A:
undetectable		 3bgdB-5ux5A:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vdn GLUTATHIONE
OXIDOREDUCTASE

(Yersinia pestis) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 VAL A 180
LEU A 196
PRO A 177
TRP A  91
 None
 1.09A 3bgdB-5vdnA:
2.8		 3bgdB-5vdnA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vm1 XYLULOKINASE

(Brucella ovis) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 GLY A  74
VAL A 229
LEU A 161
TRP A 221
 None
 0.90A 3bgdB-5vm1A:
undetectable		 3bgdB-5vm1A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xmd EPOXIDE HYDROLASE A

(Vigna radiata) 		no annotation 4 PHE A  29
VAL A  18
LEU A  86
PRO A  57
 None
 1.08A 3bgdB-5xmdA:
undetectable		 3bgdB-5xmdA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xtd NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL

(Homo sapiens) 		PF01370
(Epimerase) 		4 PHE J  64
GLY J  66
VAL J  70
LEU J  94
 None
 1.04A 3bgdB-5xtdJ:
undetectable		 3bgdB-5xtdJ:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z5c CYSTEINE SYNTHASE

(Fusobacterium
nucleatum) 		no annotation 4 GLY A 186
VAL A 183
LEU A 216
PRO A 207
 PLP  A 401 (-3.5A)
PLP  A 401 (-4.0A)
None
None
 1.09A 3bgdB-5z5cA:
2.8		 3bgdB-5z5cA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cph TCR BETA CHAIN

(Homo sapiens) 		no annotation 4 GLY E 232
VAL E 136
LEU E 130
PRO E 168
 None
 1.14A 3bgdB-6cphE:
undetectable		 3bgdB-6cphE:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6deg BETA SLIDING CLAMP

(Bartonella
birtlesii) 		no annotation 4 PHE A 131
VAL A 193
LEU A 172
PRO A 190
 None
 0.93A 3bgdB-6degA:
undetectable		 3bgdB-6degA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eic MYCOBACTERIUM
TUBERCULOSIS
MONOGLYCERIDE LIPASE

(Mycobacterium
tuberculosis) 		no annotation 4 GLY C 114
VAL C 137
LEU C 237
PRO C 135
 None
 1.08A 3bgdB-6eicC:
undetectable		 3bgdB-6eicC:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6en4 SPLICING FACTOR 3B
SUBUNIT 3

(Homo sapiens) 		no annotation 4 GLY A 247
VAL A 238
LEU A 315
PRO A 245
 None
 1.07A 3bgdB-6en4A:
undetectable		 3bgdB-6en4A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6exs PEPTIDE ABC
TRANSPORTER PERMEASE

(Staphylococcus
hominis) 		no annotation 4 ARG A 337
GLY A 339
LEU A 322
ARG A 184
 None
 1.15A 3bgdB-6exsA:
undetectable		 3bgdB-6exsA:
15.89