SIMILAR PATTERNS OF AMINO ACIDS FOR 3BGD_A_PM6A302_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cok PROTEIN (SECOND
SPLICE VARIANT P73)

(Homo sapiens) 		PF07647
(SAM_2) 		4 THR A  24
PHE A  23
LEU A   7
LEU A  11
 None
 1.13A 3bgdA-1cokA:
undetectable		 3bgdA-1cokA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eso CU, ZN SUPEROXIDE
DISMUTASE

(Escherichia
coli) 		PF00080
(Sod_Cu) 		4 HIS A  41
PHE A  43
LEU A  36
LEU A  33
 None
 1.18A 3bgdA-1esoA:
0.0		 3bgdA-1esoA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE

(Homo sapiens) 		PF00884
(Sulfatase) 		4 THR A 164
PHE A 162
LEU A 232
LEU A 234
 None
 1.03A 3bgdA-1fsuA:
0.0		 3bgdA-1fsuA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jhd SULFATE
ADENYLYLTRANSFERASE

(Sulfur-oxidizing
endosymbiont of
Riftia
pachyptila) 		PF01747
(ATP-sulfurylase)
PF14306
(PUA_2) 		4 THR A 148
PHE A 149
GLN A  39
LEU A 270
 BR  A2007 ( 4.6A)
None
None
None
 1.18A 3bgdA-1jhdA:
0.0		 3bgdA-1jhdA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jqo PHOSPHOENOLPYRUVATE
CARBOXYLASE

(Zea mays) 		PF00311
(PEPcase) 		4 THR A 784
GLN A 905
LEU A 848
LEU A 909
 None
 0.95A 3bgdA-1jqoA:
0.0		 3bgdA-1jqoA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kqf FORMATE
DEHYDROGENASE,
NITRATE-INDUCIBLE,
MAJOR SUBUNIT

(Escherichia
coli) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 HIS A 237
PHE A 241
LEU A 445
LEU A 407
 MGD  A1019 ( 4.5A)
None
None
None
 0.79A 3bgdA-1kqfA:
2.7		 3bgdA-1kqfA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kqg FORMATE
DEHYDROGENASE,
NITRATE-INDUCIBLE,
IRON-SULFUR SUBUNIT

(Escherichia
coli) 		PF09163
(Form-deh_trans)
PF12800
(Fer4_4)
PF13247
(Fer4_11) 		4 HIS B 229
GLN B 233
LEU B  94
LEU B 236
 None
 0.88A 3bgdA-1kqgB:
0.0		 3bgdA-1kqgB:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oal SUPEROXIDE DISMUTASE

(Photobacterium
leiognathi) 		PF00080
(Sod_Cu) 		4 HIS A  42
PHE A  44
LEU A  37
LEU A  34
 None
 1.09A 3bgdA-1oalA:
0.0		 3bgdA-1oalA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pc6 PROTEIN NINB

(Escherichia
virus Lambda) 		PF05772
(NinB) 		4 THR A  77
PHE A  76
LEU A  49
LEU A  53
 BME  A 300 (-3.4A)
None
None
None
 0.88A 3bgdA-1pc6A:
0.0		 3bgdA-1pc6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pzn DNA REPAIR AND
RECOMBINATION
PROTEIN RAD51

(Pyrococcus
furiosus) 		PF08423
(Rad51)
PF14520
(HHH_5) 		4 THR A 241
PHE A 244
GLN A 211
LEU A 265
 None
 1.12A 3bgdA-1pznA:
undetectable		 3bgdA-1pznA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rpt PROSTATIC ACID
PHOSPHATASE

(Rattus
norvegicus) 		PF00328
(His_Phos_2) 		4 HIS A 282
THR A   7
LEU A 264
LEU A 231
 None
 1.19A 3bgdA-1rptA:
undetectable		 3bgdA-1rptA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sky F1-ATPASE

(Bacillus sp.
PS3) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		4 THR B 148
GLN B 186
LEU B 316
LEU B 257
 None
 1.21A 3bgdA-1skyB:
2.5		 3bgdA-1skyB:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1thg LIPASE 2

(Galactomyces
candidus) 		PF00135
(COesterase) 		4 THR A 356
PHE A 462
LEU A  77
LEU A  73
 None
 1.18A 3bgdA-1thgA:
undetectable		 3bgdA-1thgA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE

(Nostoc sp. PCC
7120) 		PF00266
(Aminotran_5) 		4 PHE A 134
GLN A 164
LEU A 151
LEU A 153
 None
 1.11A 3bgdA-1vjoA:
undetectable		 3bgdA-1vjoA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wk2 HYPOTHETICAL PROTEIN

(Thermus
thermophilus) 		PF04266
(ASCH) 		4 HIS A  34
THR A  32
LEU A  38
LEU A   8
 None
 0.82A 3bgdA-1wk2A:
undetectable		 3bgdA-1wk2A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x1f SIGNAL-TRANSDUCING
ADAPTOR PROTEIN 1

(Homo sapiens) 		PF00169
(PH) 		4 THR A  70
PHE A  82
LEU A  66
LEU A  84
 None
 1.17A 3bgdA-1x1fA:
undetectable		 3bgdA-1x1fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aqt SUPEROXIDE DISMUTASE
[CU-ZN]

(Neisseria
meningitidis) 		no annotation 4 HIS C  76
PHE C  78
LEU C  71
LEU C  68
 None
 1.09A 3bgdA-2aqtC:
undetectable		 3bgdA-2aqtC:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2byk CHRAC-14
CHRAC-16

(Drosophila
melanogaster) 		PF00808
(CBFD_NFYB_HMF) 		4 THR A  63
PHE A  66
LEU B  23
LEU A  74
 None
 1.04A 3bgdA-2bykA:
undetectable		 3bgdA-2bykA:
17.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2bzg THIOPURINE
S-METHYLTRANSFERASE

(Homo sapiens) 		PF05724
(TPMT) 		5 HIS A  52
THR A  55
GLN A 179
LEU A 217
LEU A 241
 None
 0.52A 3bgdA-2bzgA:
39.3		 3bgdA-2bzgA:
71.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ch1 3-HYDROXYKYNURENINE
TRANSAMINASE

(Anopheles
gambiae) 		PF00266
(Aminotran_5) 		4 PHE A 130
GLN A 160
LEU A 147
LEU A 149
 None
 0.96A 3bgdA-2ch1A:
undetectable		 3bgdA-2ch1A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e5o ACTIVATING SIGNAL
COINTEGRATOR 1

(Homo sapiens) 		PF04266
(ASCH) 		4 HIS A  36
THR A  34
LEU A  40
LEU A  10
 None
 0.89A 3bgdA-2e5oA:
undetectable		 3bgdA-2e5oA:
20.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gb4 THIOPURINE
S-METHYLTRANSFERASE

(Mus musculus) 		PF05724
(TPMT) 		6 HIS A  47
THR A  50
PHE A  51
GLN A 174
LEU A 212
LEU A 236
 None
 0.26A 3bgdA-2gb4A:
33.0		 3bgdA-2gb4A:
95.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gdj DNA REPAIR AND
RECOMBINATION
PROTEIN RADA

(Methanococcus
voltae) 		PF08423
(Rad51) 		4 HIS A 280
THR A 214
PHE A 217
GLN A 188
 None
 1.16A 3bgdA-2gdjA:
undetectable		 3bgdA-2gdjA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ik8 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(I),
ALPHA-1 SUBUNIT

(Homo sapiens) 		PF00503
(G-alpha) 		4 HIS A 322
THR A 324
PHE A 323
LEU A 266
 None
 1.07A 3bgdA-2ik8A:
2.4		 3bgdA-2ik8A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l9b MRNA
3'-END-PROCESSING
PROTEIN RNA15

(Saccharomyces
cerevisiae) 		no annotation 4 THR A 209
PHE A 207
LEU A 227
LEU A 224
 None
 1.09A 3bgdA-2l9bA:
undetectable		 3bgdA-2l9bA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2og7 ASPARAGINE OXYGENASE

(Streptomyces
coelicolor) 		PF02668
(TauD) 		4 HIS A 262
THR A 266
PHE A 263
LEU A 195
 None
 1.13A 3bgdA-2og7A:
undetectable		 3bgdA-2og7A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okx RHAMNOSIDASE B

(Bacillus sp.
GL1) 		PF05592
(Bac_rhamnosid)
PF08531
(Bac_rhamnosid_N)
PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C) 		4 HIS A 299
GLN A 278
LEU A 294
LEU A 292
 None
 0.95A 3bgdA-2okxA:
undetectable		 3bgdA-2okxA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oyy HEXAMERIC CYTOCHROME

(Ruegeria
pomeroyi) 		PF11534
(HTHP) 		4 HIS A  60
THR A  63
LEU A  21
LEU A  17
 None
 1.11A 3bgdA-2oyyA:
undetectable		 3bgdA-2oyyA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qvp UNCHARACTERIZED
PROTEIN

(Shewanella
amazonensis) 		PF04952
(AstE_AspA) 		4 HIS A 152
GLN A  56
LEU A  44
LEU A  54
 None
 1.02A 3bgdA-2qvpA:
undetectable		 3bgdA-2qvpA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r2d ZN-DEPENDENT
HYDROLASES

(Agrobacterium
fabrum) 		PF00753
(Lactamase_B) 		4 PHE A   6
GLN A  49
LEU A  94
LEU A  99
 None
 1.20A 3bgdA-2r2dA:
undetectable		 3bgdA-2r2dA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9v ATP SYNTHASE SUBUNIT
ALPHA

(Thermotoga
maritima) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		4 THR A 149
GLN A 187
LEU A 317
LEU A 258
 None
 1.14A 3bgdA-2r9vA:
2.4		 3bgdA-2r9vA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wwo SUPEROXIDE DISMUTASE
[CU-ZN]

(Yersinia
pseudotuberculosis) 		PF00080
(Sod_Cu) 		4 HIS A  51
PHE A  53
LEU A  46
LEU A  43
 None
 1.12A 3bgdA-2wwoA:
undetectable		 3bgdA-2wwoA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zpa UNCHARACTERIZED
PROTEIN YPFI

(Escherichia
coli) 		PF05127
(Helicase_RecD)
PF08351
(DUF1726)
PF13718
(GNAT_acetyltr_2)
PF17176
(tRNA_bind_3) 		4 HIS A 162
GLN A  13
LEU A 160
LEU A  10
 None
 1.05A 3bgdA-2zpaA:
2.5		 3bgdA-2zpaA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zuc DNA REPAIR AND
RECOMBINATION
PROTEIN RADA

(Sulfolobus
solfataricus) 		PF08423
(Rad51)
PF14520
(HHH_5) 		4 THR A 213
PHE A 216
GLN A 187
LEU A 237
 None
 1.16A 3bgdA-2zucA:
undetectable		 3bgdA-2zucA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zwv PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE

(Thermus
thermophilus) 		PF05175
(MTS) 		4 HIS A 286
GLN A 272
LEU A 265
LEU A 269
 None
 1.20A 3bgdA-2zwvA:
6.2		 3bgdA-2zwvA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aiz DNA POLYMERASE
SLIDING CLAMP C

(Sulfurisphaera
tokodaii) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 THR C 138
PHE C 139
LEU C 185
LEU C 178
 None
 1.03A 3bgdA-3aizC:
undetectable		 3bgdA-3aizC:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aup BASIC 7S GLOBULIN

(Glycine max) 		PF14541
(TAXi_C)
PF14543
(TAXi_N) 		4 HIS A  46
PHE A 139
LEU A  96
LEU A 111
 None
 0.94A 3bgdA-3aupA:
undetectable		 3bgdA-3aupA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE

(Shewanella
denitrificans) 		PF04952
(AstE_AspA) 		4 HIS A 153
GLN A  57
LEU A  45
LEU A  55
 None
 1.05A 3bgdA-3b2yA:
undetectable		 3bgdA-3b2yA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cqc NUCLEAR PORE COMPLEX
PROTEIN NUP133

(Homo sapiens) 		no annotation 4 HIS B1004
THR B1007
LEU B1054
LEU B1031
 None
 1.16A 3bgdA-3cqcB:
undetectable		 3bgdA-3cqcB:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3csv AMINOGLYCOSIDE
PHOSPHOTRANSFERASE

(Ruegeria sp.
TM1040) 		PF01636
(APH) 		4 HIS A 218
GLN A 267
LEU A 178
LEU A 174
 None
 1.12A 3bgdA-3csvA:
undetectable		 3bgdA-3csvA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cx6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-13
SUBUNIT

(Mus musculus) 		PF00503
(G-alpha) 		4 HIS A 345
THR A 347
PHE A 346
LEU A 288
 None
 1.15A 3bgdA-3cx6A:
undetectable		 3bgdA-3cx6A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d5l REGULATORY PROTEIN
RECX

(Lactobacillus
reuteri) 		PF02631
(RecX) 		4 THR A 189
PHE A 192
LEU A 167
LEU A 163
 None
 1.15A 3bgdA-3d5lA:
undetectable		 3bgdA-3d5lA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 THR A 180
PHE A 179
LEU A 237
LEU A 210
 None
 1.13A 3bgdA-3eb7A:
undetectable		 3bgdA-3eb7A:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fef PUTATIVE GLUCOSIDASE
LPLD,
ALPHA-GALACTURONIDAS
E

(Bacillus
subtilis) 		PF02056
(Glyco_hydro_4)
PF11975
(Glyco_hydro_4C) 		4 HIS A 210
THR A 212
PHE A 211
LEU A 277
 MG  A   1 (-3.5A)
None
None
None
 1.13A 3bgdA-3fefA:
undetectable		 3bgdA-3fefA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gs6 BETA-HEXOSAMINIDASE

(Vibrio cholerae) 		PF00933
(Glyco_hydro_3) 		4 HIS A 108
PHE A  71
GLN A  63
LEU A 105
 None
 1.09A 3bgdA-3gs6A:
undetectable		 3bgdA-3gs6A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hxw ALANYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF01411
(tRNA-synt_2c) 		4 THR A  88
PHE A  89
LEU A 293
LEU A  28
 None
 1.14A 3bgdA-3hxwA:
undetectable		 3bgdA-3hxwA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4r NUCLEAR PORE COMPLEX
PROTEIN NUP133

(Homo sapiens) 		PF03177
(Nucleoporin_C) 		4 HIS B1004
THR B1007
LEU B1054
LEU B1031
 None
 1.18A 3bgdA-3i4rB:
undetectable		 3bgdA-3i4rB:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9u HEME OXYGENASE 1

(Rattus
norvegicus) 		PF01126
(Heme_oxygenase) 		4 HIS A 132
THR A 135
LEU A 118
LEU A  61
 None
HEM  A 300 (-4.8A)
None
None
 1.00A 3bgdA-3i9uA:
undetectable		 3bgdA-3i9uA:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ieh PUTATIVE
METALLOPEPTIDASE

(Shewanella
baltica) 		PF04952
(AstE_AspA) 		4 HIS A 153
GLN A  57
LEU A  45
LEU A  55
 GOL  A 279 (-4.5A)
None
None
None
 1.08A 3bgdA-3iehA:
undetectable		 3bgdA-3iehA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oee ATP SYNTHASE SUBUNIT
ALPHA

(Saccharomyces
cerevisiae) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		4 THR A 150
GLN A 188
LEU A 326
LEU A 267
 None
 1.10A 3bgdA-3oeeA:
undetectable		 3bgdA-3oeeA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pt5 NANS (YJHS), A
9-O-ACETYL
N-ACETYLNEURAMINIC
ACID ESTERASE

(Escherichia
coli) 		PF03629
(SASA) 		4 HIS A  49
THR A  50
PHE A  47
GLN A  76
 None
 1.11A 3bgdA-3pt5A:
undetectable		 3bgdA-3pt5A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6q CD180 ANTIGEN

(Mus musculus) 		PF13855
(LRR_8) 		4 THR A  72
GLN A 100
LEU A  84
LEU A  82
 None
 1.16A 3bgdA-3t6qA:
undetectable		 3bgdA-3t6qA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6q CD180 ANTIGEN

(Mus musculus) 		PF13855
(LRR_8) 		4 THR A  96
GLN A 100
LEU A  84
LEU A  82
 None
 1.00A 3bgdA-3t6qA:
undetectable		 3bgdA-3t6qA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tc3 UV DAMAGE
ENDONUCLEASE

(Sulfolobus
acidocaldarius) 		PF03851
(UvdE) 		4 HIS A  68
PHE A  71
LEU A  22
LEU A  25
 None
 1.17A 3bgdA-3tc3A:
undetectable		 3bgdA-3tc3A:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tjz ADP-RIBOSYLATION
FACTOR 1
COATOMER SUBUNIT
GAMMA

(Bos taurus;
Saccharomyces
cerevisiae) 		PF00025
(Arf)
PF01602
(Adaptin_N) 		4 HIS A  80
THR B  67
PHE B  70
LEU A  77
 None
 1.11A 3bgdA-3tjzA:
undetectable		 3bgdA-3tjzA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tpa HEME-BINDING PROTEIN
A

(Glaesserella
parasuis) 		PF00496
(SBP_bac_5) 		4 THR A  85
PHE A  86
GLN A 172
LEU A 173
 None
 1.17A 3bgdA-3tpaA:
undetectable		 3bgdA-3tpaA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u3i NUCLEOCAPSID PROTEIN

(Crimean-Congo
hemorrhagic
fever
orthonairovirus) 		PF02477
(Nairo_nucleo) 		4 THR A 323
PHE A 324
LEU A  93
LEU A 314
 None
 1.06A 3bgdA-3u3iA:
undetectable		 3bgdA-3u3iA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE

(Flaveria
pringlei) 		PF00311
(PEPcase) 		4 THR A 778
GLN A 899
LEU A 842
LEU A 903
 None
 0.98A 3bgdA-3zgbA:
undetectable		 3bgdA-3zgbA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zwf ZINC
PHOSPHODIESTERASE
ELAC PROTEIN 1

(Homo sapiens) 		PF00753
(Lactamase_B)
PF12706
(Lactamase_B_2) 		4 HIS A  62
THR A  61
PHE A 187
LEU A 180
 ZN  A1364 (-3.5A)
None
None
None
 1.18A 3bgdA-3zwfA:
undetectable		 3bgdA-3zwfA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dqk BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE

(Bacillus
megaterium) 		PF00175
(NAD_binding_1)
PF00667
(FAD_binding_1) 		4 THR A 716
PHE A 719
LEU A 756
LEU A 802
 None
 1.20A 3bgdA-4dqkA:
undetectable		 3bgdA-4dqkA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e14 KYNURENINE
FORMAMIDASE

(Drosophila
melanogaster) 		PF07859
(Abhydrolase_3) 		4 HIS A 134
THR A 130
PHE A 132
GLN A 165
 None
 1.18A 3bgdA-4e14A:
undetectable		 3bgdA-4e14A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i6m ACTIN-LIKE PROTEIN
ARP9

(Saccharomyces
cerevisiae) 		PF00022
(Actin) 		4 THR B  31
PHE B  30
GLN B 433
LEU B  25
 None
 0.91A 3bgdA-4i6mB:
undetectable		 3bgdA-4i6mB:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ifs FACT COMPLEX SUBUNIT
SSRP1

(Homo sapiens) 		PF08512
(Rtt106) 		4 HIS A 363
GLN A 252
LEU A 208
LEU A 276
 None
 0.83A 3bgdA-4ifsA:
undetectable		 3bgdA-4ifsA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iyp IMMUNOGLOBULIN-BINDI
NG PROTEIN 1

(Homo sapiens) 		PF04177
(TAP42) 		4 HIS A 196
GLN A 198
LEU A 172
LEU A 168
 None
 1.18A 3bgdA-4iypA:
undetectable		 3bgdA-4iypA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j4s NUCLEOCAPSID PROTEIN

(SFTS
phlebovirus) 		PF05733
(Tenui_N) 		4 THR A  54
PHE A  56
LEU A  92
LEU A  86
 None
 1.15A 3bgdA-4j4sA:
undetectable		 3bgdA-4j4sA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jf7 HEMAGGLUTININ-NEURAM
INIDASE

(Mammalian
rubulavirus 5) 		no annotation 4 THR D 177
PHE D 194
LEU D 218
LEU D 216
 None
 1.19A 3bgdA-4jf7D:
undetectable		 3bgdA-4jf7D:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jgv NUCLEAR RECEPTOR
SUBFAMILY 4 GROUP A
MEMBER 1

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 PHE A 387
GLN A 474
LEU A 468
LEU A 470
 None
 0.99A 3bgdA-4jgvA:
undetectable		 3bgdA-4jgvA:
26.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mec HEME OXYGENASE 1

(Rattus
norvegicus) 		PF01126
(Heme_oxygenase) 		4 HIS A 132
THR A 135
LEU A 118
LEU A  61
 None
ZNH  A 300 (-4.7A)
None
None
 1.10A 3bgdA-4mecA:
undetectable		 3bgdA-4mecA:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oun MINI-RIBONUCLEASE 3

(Bacillus
subtilis) 		PF00636
(Ribonuclease_3) 		4 THR A  92
PHE A  91
LEU A 132
LEU A 128
 None
 1.08A 3bgdA-4ounA:
undetectable		 3bgdA-4ounA:
29.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pph CONGLUTIN GAMMA

(Lupinus
angustifolius) 		PF14541
(TAXi_C)
PF14543
(TAXi_N) 		4 HIS A  51
PHE A 144
LEU A 103
LEU A 118
 EDO  A 509 ( 4.1A)
None
None
None
 0.95A 3bgdA-4pphA:
undetectable		 3bgdA-4pphA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q16 NH(3)-DEPENDENT
NAD(+) SYNTHETASE

(Deinococcus
radiodurans) 		PF02540
(NAD_synthase) 		4 THR A 174
PHE A 261
LEU A 244
LEU A  19
 None
 0.80A 3bgdA-4q16A:
undetectable		 3bgdA-4q16A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tv7 HTH-TYPE
TRANSCRIPTIONAL
REGULATORY PROTEIN
GABR

(Bacillus
subtilis) 		PF00155
(Aminotran_1_2)
PF00392
(GntR) 		4 THR A 350
PHE A 354
LEU A 318
LEU A 315
 None
 1.08A 3bgdA-4tv7A:
3.7		 3bgdA-4tv7A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd4 HEME OXYGENASE 1

(Homo sapiens) 		PF01126
(Heme_oxygenase) 		4 HIS A 132
THR A 135
LEU A 118
LEU A  61
 None
HEM  A 300 ( 4.9A)
None
None
 1.04A 3bgdA-4wd4A:
undetectable		 3bgdA-4wd4A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zz7 METHYLMALONATE-SEMIA
LDEHYDE
DEHYDROGENASE

(Oceanimonas
doudoroffii) 		PF00171
(Aldedh) 		4 HIS A 461
PHE A 449
LEU A 456
LEU A 246
 None
NAD  A 501 (-4.5A)
None
NAD  A 501 (-3.5A)
 1.19A 3bgdA-4zz7A:
undetectable		 3bgdA-4zz7A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aid MEP2

(Candida
albicans) 		PF00909
(Ammonium_transp) 		4 THR A   6
PHE A   5
GLN A  22
LEU A  19
 None
 1.18A 3bgdA-5aidA:
undetectable		 3bgdA-5aidA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b04 PROBABLE TRANSLATION
INITIATION FACTOR
EIF-2B SUBUNIT BETA
PROBABLE TRANSLATION
INITIATION FACTOR
EIF-2B SUBUNIT DELTA

(Schizosaccharomyces
pombe) 		PF01008
(IF-2B) 		4 HIS G 366
GLN C 298
LEU G 439
LEU G 363
 None
 1.05A 3bgdA-5b04G:
undetectable		 3bgdA-5b04G:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b47 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT

(Sulfurisphaera
tokodaii) 		PF01558
(POR)
PF01855
(POR_N)
PF17147
(PFOR_II) 		4 THR A 340
GLN A 251
LEU A 392
LEU A 248
 None
 0.89A 3bgdA-5b47A:
undetectable		 3bgdA-5b47A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT

(Sulfurisphaera
tokodaii) 		PF02775
(TPP_enzyme_C)
PF12367
(PFO_beta_C) 		4 HIS B  52
PHE B  53
GLN B  25
LEU B  21
 None
 1.09A 3bgdA-5b48B:
3.2		 3bgdA-5b48B:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5csl ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF01039
(Carboxyl_trans)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2)
PF08326
(ACC_central) 		4 HIS A 298
THR A 559
LEU A 378
LEU A 367
 None
 1.09A 3bgdA-5cslA:
undetectable		 3bgdA-5cslA:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dn6 ATP SYNTHASE SUBUNIT
ALPHA

(Paracoccus
denitrificans) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		4 THR A 148
GLN A 186
LEU A 325
LEU A 266
 None
 1.18A 3bgdA-5dn6A:
2.3		 3bgdA-5dn6A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dn7 PROTEIN FAM179B

(Mus musculus) 		no annotation 4 THR A 386
GLN A 427
LEU A 420
LEU A 424
 None
 0.98A 3bgdA-5dn7A:
undetectable		 3bgdA-5dn7A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ejy MYOSIN-I HEAVY CHAIN

(Dictyostelium
discoideum) 		PF00784
(MyTH4) 		4 PHE A  99
GLN A 144
LEU A  65
LEU A  83
 None
 1.15A 3bgdA-5ejyA:
undetectable		 3bgdA-5ejyA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3

(Arabidopsis
thaliana) 		PF00311
(PEPcase) 		4 THR A 781
GLN A 902
LEU A 845
LEU A 906
 None
 0.88A 3bgdA-5fdnA:
undetectable		 3bgdA-5fdnA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fl7 ATP SYNTHASE SUBUNIT
ALPHA

(Yarrowia
lipolytica) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		4 THR A 174
GLN A 212
LEU A 350
LEU A 291
 None
 1.15A 3bgdA-5fl7A:
2.9		 3bgdA-5fl7A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fx8 LINOLEATE
11-LIPOXYGENASE

(Gaeumannomyces
avenae) 		PF00305
(Lipoxygenase) 		4 PHE A 188
GLN A 235
LEU A 179
LEU A 214
 None
 0.49A 3bgdA-5fx8A:
undetectable		 3bgdA-5fx8A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gvb WD REPEAT AND
HMG-BOX DNA-BINDING
PROTEIN 1

(Homo sapiens) 		PF12341
(Mcl1_mid) 		4 THR A 637
PHE A 632
GLN A 582
LEU A 603
 None
 1.07A 3bgdA-5gvbA:
undetectable		 3bgdA-5gvbA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gyq SPIKE GLYCOPROTEIN

(Rousettus bat
coronavirus
HKU9) 		PF09408
(Spike_rec_bind) 		4 HIS A  46
PHE A 107
LEU A  78
LEU A 153
 None
 1.17A 3bgdA-5gyqA:
undetectable		 3bgdA-5gyqA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzg F-BOX/LRR-REPEAT
MAX2 HOMOLOG

(Oryza sativa) 		no annotation 4 PHE B 529
GLN B 533
LEU B 447
LEU B 538
 None
 1.04A 3bgdA-5hzgB:
undetectable		 3bgdA-5hzgB:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ik2 ATP SYNTHASE SUBUNIT
ALPHA

(Caldalkalibacillus
thermarum) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		4 THR A 148
GLN A 186
LEU A 316
LEU A 257
 None
 1.06A 3bgdA-5ik2A:
2.0		 3bgdA-5ik2A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ogs WD REPEAT AND
HMG-BOX DNA-BINDING
PROTEIN 1

(Homo sapiens) 		no annotation 4 THR A 637
PHE A 632
GLN A 582
LEU A 603
 None
 1.07A 3bgdA-5ogsA:
undetectable		 3bgdA-5ogsA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ums FACT COMPLEX SUBUNIT
SSRP1

(Homo sapiens) 		no annotation 4 HIS A 363
GLN A 252
LEU A 208
LEU A 276
 None
 0.89A 3bgdA-5umsA:
undetectable		 3bgdA-5umsA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vop 5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE

(Thermus
thermophilus) 		no annotation 4 HIS A 431
THR A 434
LEU A 392
LEU A 396
 None
 1.10A 3bgdA-5vopA:
undetectable		 3bgdA-5vopA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjh POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE

(Ideonella
sakaiensis) 		no annotation 4 THR A 286
PHE A 229
LEU A 199
LEU A 230
 None
 1.20A 3bgdA-5xjhA:
undetectable		 3bgdA-5xjhA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y50 PROTEIN
DETOXIFICATION 14

(Arabidopsis
thaliana) 		no annotation 4 HIS A 107
THR A 110
LEU A  91
LEU A  88
 None
 1.19A 3bgdA-5y50A:
undetectable		 3bgdA-5y50A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z9s GLYCOSYL HYDROLASE
FAMILY 3 PROTEIN

(Bifidobacterium
longum) 		no annotation 4 THR A 244
GLN A 183
LEU A 351
LEU A 192
 None
 0.96A 3bgdA-5z9sA:
undetectable		 3bgdA-5z9sA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c0t CGMP-DEPENDENT
PROTEIN KINASE 1

(Homo sapiens) 		no annotation 4 THR A 460
PHE A 463
LEU A 446
LEU A 492
 None
 1.14A 3bgdA-6c0tA:
undetectable		 3bgdA-6c0tA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY

(Elizabethkingia
anophelis) 		no annotation 4 THR A 256
PHE A 255
LEU A 264
LEU A 240
 None
 1.17A 3bgdA-6cy1A:
undetectable		 3bgdA-6cy1A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5d ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL

(Trypanosoma
brucei) 		no annotation 4 THR A 161
GLN A 199
LEU A 337
LEU A 278
 None
 1.12A 3bgdA-6f5dA:
undetectable		 3bgdA-6f5dA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fcx METHYLENETETRAHYDROF
OLATE REDUCTASE

(Homo sapiens) 		no annotation 4 THR A 235
PHE A 237
LEU A 305
LEU A 309
 None
 1.17A 3bgdA-6fcxA:
undetectable		 3bgdA-6fcxA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fkh ATP SYNTHASE SUBUNIT
ALPHA, CHLOROPLASTIC

(Spinacia
oleracea) 		no annotation 4 THR C 149
GLN C 187
LEU C 317
LEU C 258
 None
 1.19A 3bgdA-6fkhC:
2.7		 3bgdA-6fkhC:
17.22