SIMILAR PATTERNS OF AMINO ACIDS FOR 3BCR_A_AZZA940_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ais PROTEIN
(TRANSCRIPTION
INITIATION FACTOR
IIB)

(Pyrococcus
woesei) 		PF00382
(TFIIB) 		4 ASN B1196
PHE B1192
ALA B1140
GLY B1144
 None
 1.04A 3bcrA-1aisB:
undetectable		 3bcrA-1aisB:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aor ALDEHYDE FERREDOXIN
OXIDOREDUCTASE

(Pyrococcus
furiosus) 		PF01314
(AFOR_C)
PF02730
(AFOR_N) 		4 ASN A 260
PHE A 261
ALA A 352
GLY A 349
 None
 0.89A 3bcrA-1aorA:
undetectable		 3bcrA-1aorA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b25 PROTEIN
(FORMALDEHYDE
FERREDOXIN
OXIDOREDUCTASE)

(Pyrococcus
furiosus) 		PF01314
(AFOR_C)
PF02730
(AFOR_N) 		4 ASN A 257
PHE A 258
ALA A 347
GLY A 343
 None
 1.21A 3bcrA-1b25A:
undetectable		 3bcrA-1b25A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ebd DIHYDROLIPOAMIDE
DEHYDROGENASE

(Geobacillus
stearothermophilus) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 ASN A 197
ALA A 194
GLY A 192
TYR A 195
 None
 1.21A 3bcrA-1ebdA:
undetectable		 3bcrA-1ebdA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ig8 HEXOKINASE PII

(Saccharomyces
cerevisiae) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		4 ASN A 267
ALA A 239
GLY A 238
TYR A 240
 None
 1.10A 3bcrA-1ig8A:
undetectable		 3bcrA-1ig8A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jif BLEOMYCIN-BINDING
PROTEIN

(Streptomyces
verticillus) 		no annotation 4 ASN A  19
PHE A  22
ALA A 112
GLY A 113
 None
 1.22A 3bcrA-1jifA:
undetectable		 3bcrA-1jifA:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nog CONSERVED
HYPOTHETICAL PROTEIN
TA0546

(Thermoplasma
acidophilum) 		PF01923
(Cob_adeno_trans) 		4 PHE A  38
ALA A  42
GLY A  40
TYR A  41
 None
 1.15A 3bcrA-1nogA:
undetectable		 3bcrA-1nogA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1omo ALANINE
DEHYDROGENASE

(Archaeoglobus
fulgidus) 		PF02423
(OCD_Mu_crystall) 		4 ASN A 214
PHE A 288
ALA A 117
GLY A 114
 ASN  A 214 ( 0.6A)
PHE  A 288 ( 1.3A)
ALA  A 117 ( 0.0A)
GLY  A 114 ( 0.0A)
 1.11A 3bcrA-1omoA:
undetectable		 3bcrA-1omoA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ope SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE

(Sus scrofa) 		PF01144
(CoA_trans) 		4 ASN A  51
PHE A  25
GLY A 385
TYR A  76
 None
 1.11A 3bcrA-1opeA:
undetectable		 3bcrA-1opeA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sk4 PEPTIDOGLYCAN
RECOGNITION PROTEIN
I-ALPHA

(Homo sapiens) 		PF01510
(Amidase_2) 		4 PHE A 281
ALA A 210
GLY A 211
TYR A 280
 None
 1.22A 3bcrA-1sk4A:
undetectable		 3bcrA-1sk4A:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tuj ODORANT BINDING
PROTEIN ASP2

(Apis mellifera) 		PF01395
(PBP_GOBP) 		4 ASN A  99
ALA A 100
GLY A 110
TYR A 113
 None
 1.20A 3bcrA-1tujA:
undetectable		 3bcrA-1tujA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uf2 CORE PROTEIN P3

(Rice dwarf
virus) 		PF09231
(RDV-p3) 		4 ASN A 500
ALA A 499
GLY A 498
TYR A 497
 None
 1.20A 3bcrA-1uf2A:
undetectable		 3bcrA-1uf2A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w85 PYRUVATE
DEHYDROGENASE E1
COMPONENT, ALPHA
SUBUNIT

(Geobacillus
stearothermophilus) 		PF00676
(E1_dh) 		4 ASN A 202
PHE A 266
GLY A 269
TYR A 268
 MG  A1368 ( 2.9A)
None
None
None
 1.02A 3bcrA-1w85A:
undetectable		 3bcrA-1w85A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zef ALKALINE PHOSPHATASE

(Homo sapiens) 		PF00245
(Alk_phosphatase) 		4 ASN A  84
PHE A 107
ALA A  94
GLY A  93
 None
PHE  A 802 (-4.4A)
None
SEP  A  92 ( 2.4A)
 0.99A 3bcrA-1zefA:
undetectable		 3bcrA-1zefA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2akc CLASS A NONSPECIFIC
ACID PHOSPHATASE
PHON

(Salmonella
enterica) 		PF01569
(PAP2) 		4 PHE A  58
ALA A  62
GLY A  60
TYR A  61
 None
 1.16A 3bcrA-2akcA:
undetectable		 3bcrA-2akcA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fck RIBOSOMAL-PROTEIN-SE
RINE
ACETYLTRANSFERASE,
PUTATIVE

(Vibrio cholerae) 		PF13302
(Acetyltransf_3) 		4 ASN A  61
ALA A  67
GLY A  69
TYR A  68
 None
 1.13A 3bcrA-2fckA:
undetectable		 3bcrA-2fckA:
13.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus) 		PF00343
(Phosphorylase) 		5 ASN A 282
PHE A 285
ALA A 610
GLY A 612
TYR A 613
 None
 0.36A 3bcrA-2gj4A:
57.4		 3bcrA-2gj4A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i00 ACETYLTRANSFERASE,
GNAT FAMILY

(Enterococcus
faecalis) 		PF13527
(Acetyltransf_9)
PF13530
(SCP2_2) 		4 ASN A 247
ALA A 250
GLY A 227
TYR A 245
 None
 1.09A 3bcrA-2i00A:
undetectable		 3bcrA-2i00A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nwb CONSERVED DOMAIN
PROTEIN

(Shewanella
oneidensis) 		PF08933
(DUF1864) 		4 ASN A 235
ALA A 234
GLY A 233
TYR A 221
 HEM  A 401 (-2.6A)
None
None
None
 1.12A 3bcrA-2nwbA:
undetectable		 3bcrA-2nwbA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ox4 PUTATIVE MANDELATE
RACEMASE

(Zymomonas
mobilis) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ASN A 120
ALA A 332
GLY A 117
TYR A 113
 None
None
GOL  A3414 (-3.8A)
None
 0.97A 3bcrA-2ox4A:
undetectable		 3bcrA-2ox4A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r3v MEVALONATE KINASE

(Homo sapiens) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 ASN A 205
PHE A 190
ALA A 189
GLY A 192
 None
 1.18A 3bcrA-2r3vA:
undetectable		 3bcrA-2r3vA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v7y CHAPERONE PROTEIN
DNAK

(Geobacillus
kaustophilus) 		PF00012
(HSP70) 		4 ASN A 121
PHE A 120
ALA A 123
GLY A  72
 None
 1.12A 3bcrA-2v7yA:
undetectable		 3bcrA-2v7yA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vxo GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]

(Homo sapiens) 		PF00117
(GATase)
PF00958
(GMP_synt_C)
PF02540
(NAD_synthase) 		4 PHE A 140
ALA A 178
GLY A 186
TYR A 185
 None
 1.15A 3bcrA-2vxoA:
undetectable		 3bcrA-2vxoA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wj3 1-H-3-HYDROXY-4-OXOQ
UINALDINE
2,4-DIOXYGENASE

(Paenarthrobacter
nitroguajacolicus) 		PF00561
(Abhydrolase_1) 		4 ASN A 199
ALA A 195
GLY A 197
TYR A 196
 None
 1.14A 3bcrA-2wj3A:
6.7		 3bcrA-2wj3A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE

(Campylobacter
jejuni) 		PF06002
(CST-I) 		4 PHE A 254
ALA A 250
GLY A 252
TYR A 251
 None
 1.21A 3bcrA-2wqqA:
undetectable		 3bcrA-2wqqA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y8d ERYTHROCYTE MEMBRANE
PROTEIN 1

(Plasmodium
falciparum) 		PF05424
(Duffy_binding) 		4 ASN A2352
ALA A2410
GLY A2412
TYR A2411
 None
 0.96A 3bcrA-2y8dA:
undetectable		 3bcrA-2y8dA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yg6 PUTRESCINE OXIDASE

(Rhodococcus
erythropolis) 		PF01593
(Amino_oxidase) 		4 ASN A 164
PHE A 168
ALA A 318
GLY A 317
 None
 1.15A 3bcrA-2yg6A:
undetectable		 3bcrA-2yg6A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z3k LEUCYL/PHENYLALANYL-
TRNA-PROTEIN
TRANSFERASE

(Escherichia
coli) 		PF03588
(Leu_Phe_trans) 		4 PHE A  47
ALA A  41
GLY A  45
TYR A  42
 None
 1.07A 3bcrA-2z3kA:
undetectable		 3bcrA-2z3kA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z6b BASEPLATE STRUCTURAL
PROTEIN GP27

(Escherichia
virus T4) 		PF09096
(Phage-tail_2)
PF09097
(Phage-tail_1) 		4 ASN D  78
ALA D  77
GLY D   8
TYR D   9
 None
 1.22A 3bcrA-2z6bD:
undetectable		 3bcrA-2z6bD:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z8z LIPASE

(Pseudomonas sp.
MIS38) 		PF00353
(HemolysinCabind) 		4 ASN A 344
ALA A 317
GLY A 319
TYR A 318
 None
 0.92A 3bcrA-2z8zA:
undetectable		 3bcrA-2z8zA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc sp. PCC
7120) 		PF00033
(Cytochrome_B)
PF02529
(PetG) 		4 ASN A  31
ALA G  24
GLY G  20
TYR G  23
 None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
 1.00A 3bcrA-2zt9A:
undetectable		 3bcrA-2zt9A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aeb SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
CYTOCHROME B SMALL
SUBUNIT,
MITOCHONDRIAL

(Sus scrofa) 		PF05328
(CybS) 		4 ASN D 120
PHE D 119
GLY D 115
TYR D 118
 None
 1.18A 3bcrA-3aebD:
undetectable		 3bcrA-3aebD:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ail 303AA LONG
HYPOTHETICAL
ESTERASE

(Sulfurisphaera
tokodaii) 		PF07859
(Abhydrolase_3) 		4 ASN A 254
ALA A 251
GLY A 249
TYR A 252
 None
 1.12A 3bcrA-3ailA:
5.7		 3bcrA-3ailA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b8p CHAIN LENGTH
DETERMINANT PROTEIN

(Salmonella
enterica) 		PF02706
(Wzz) 		4 ASN A  78
ALA A  85
GLY A  83
TYR A  81
 None
 1.13A 3bcrA-3b8pA:
2.3		 3bcrA-3b8pA:
16.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo sapiens) 		PF00343
(Phosphorylase) 		5 ASN A 282
PHE A 285
ALA A 610
GLY A 612
TYR A 613
 None
 0.22A 3bcrA-3cemA:
66.9		 3bcrA-3cemA:
80.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f44 PUTATIVE
MONOOXYGENASE

(Lactobacillus
acidophilus) 		PF03992
(ABM) 		4 ASN A 173
ALA A 176
GLY A 149
TYR A 171
 None
 1.06A 3bcrA-3f44A:
undetectable		 3bcrA-3f44A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g6u GLUCOCORTICOID
RECEPTOR

(Rattus
norvegicus) 		PF00105
(zf-C4) 		4 ASN A 506
ALA A 509
GLY A 453
TYR A 452
 None
 1.19A 3bcrA-3g6uA:
undetectable		 3bcrA-3g6uA:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gl1 HEAT SHOCK PROTEIN
SSB1

(Saccharomyces
cerevisiae) 		PF00012
(HSP70) 		4 ASN A 153
PHE A 152
ALA A 155
GLY A  77
 None
 1.10A 3bcrA-3gl1A:
undetectable		 3bcrA-3gl1A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gnn NICOTINATE-NUCLEOTID
E PYROPHOSPHORYLASE

(Burkholderia
pseudomallei) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		4 PHE A  21
ALA A  20
GLY A  18
TYR A  17
 None
 1.21A 3bcrA-3gnnA:
undetectable		 3bcrA-3gnnA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gnq GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE, TYPE
I

(Burkholderia
pseudomallei) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 ASN A 290
PHE A 287
ALA A 292
GLY A 276
 None
 0.79A 3bcrA-3gnqA:
4.8		 3bcrA-3gnqA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h4p PROTEASOME SUBUNIT
BETA

(Methanocaldococcus
jannaschii) 		PF00227
(Proteasome)
PF10584
(Proteasome_A_N) 		4 PHE a 133
ALA a 143
GLY a 145
TYR a 144
 None
 1.08A 3bcrA-3h4pa:
undetectable		 3bcrA-3h4pa:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3heb RESPONSE REGULATOR
RECEIVER DOMAIN
PROTEIN (CHEY)

(Rhodospirillum
rubrum) 		PF00072
(Response_reg) 		4 ASN A 116
ALA A 115
GLY A 114
TYR A 111
 None
 1.18A 3bcrA-3hebA:
5.0		 3bcrA-3hebA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hmj FATTY ACID SYNTHASE
SUBUNIT ALPHA

(Saccharomyces
cerevisiae) 		PF00109
(ketoacyl-synt)
PF01648
(ACPS)
PF02801
(Ketoacyl-synt_C) 		4 ASN A1194
ALA A1195
GLY A1199
TYR A1198
 None
 1.17A 3bcrA-3hmjA:
undetectable		 3bcrA-3hmjA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hyv SULFIDE-QUINONE
REDUCTASE

(Aquifex
aeolicus) 		PF07992
(Pyr_redox_2) 		4 PHE A 157
ALA A 160
GLY A 149
TYR A 161
 None
 1.16A 3bcrA-3hyvA:
3.6		 3bcrA-3hyvA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4j AMINOTRANSFERASE,
CLASS III

(Deinococcus
radiodurans) 		PF00202
(Aminotran_3) 		4 ASN A 171
ALA A 210
GLY A 212
TYR A 213
 None
 0.95A 3bcrA-3i4jA:
undetectable		 3bcrA-3i4jA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo sapiens) 		PF00012
(HSP70) 		4 ASN A 177
PHE A 176
ALA A 179
GLY A 100
 None
 1.14A 3bcrA-3ldoA:
undetectable		 3bcrA-3ldoA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o80 HEXOKINASE

(Kluyveromyces
lactis) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		4 ASN A 266
ALA A 238
GLY A 237
TYR A 239
 None
 1.13A 3bcrA-3o80A:
undetectable		 3bcrA-3o80A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qj3 CATHEPSIN L-LIKE
PROTEIN

(Tenebrio
molitor) 		PF00112
(Peptidase_C1)
PF08246
(Inhibitor_I29) 		4 ASN A 287
PHE A 299
GLY A 248
TYR A 250
 None
 1.11A 3bcrA-3qj3A:
undetectable		 3bcrA-3qj3A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qml 78 KDA
GLUCOSE-REGULATED
PROTEIN HOMOLOG

(Saccharomyces
cerevisiae) 		PF00012
(HSP70) 		4 ASN A 197
PHE A 196
ALA A 199
GLY A 121
 None
 1.13A 3bcrA-3qmlA:
undetectable		 3bcrA-3qmlA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r44 FATTY ACYL COA
SYNTHETASE FADD13
(FATTY-ACYL-COA
SYNTHETASE)

(Mycobacterium
tuberculosis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 ASN A   3
ALA A  75
GLY A  73
TYR A  72
 None
 1.01A 3bcrA-3r44A:
undetectable		 3bcrA-3r44A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t2y SULFIDE-QUINONE
REDUCTASE, PUTATIVE

(Acidithiobacillus
ferrooxidans) 		PF07992
(Pyr_redox_2) 		4 PHE A 161
ALA A 164
GLY A 153
TYR A 165
 None
 1.19A 3bcrA-3t2yA:
4.3		 3bcrA-3t2yA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ubm FORMYL-COA:OXALATE
COA-TRANSFERASE

(Acetobacter
aceti) 		PF02515
(CoA_transf_3) 		4 ASN A  72
ALA A  33
GLY A  36
TYR A  35
 None
 1.15A 3bcrA-3ubmA:
4.1		 3bcrA-3ubmA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vss BETA-FRUCTOFURANOSID
ASE

(Microbacterium
saccharophilum) 		PF02435
(Glyco_hydro_68) 		4 ASN A 422
ALA A 428
GLY A 408
TYR A 407
 None
 1.19A 3bcrA-3vssA:
undetectable		 3bcrA-3vssA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c51 CATALASE-PEROXIDASE

(Mycobacterium
tuberculosis) 		PF00141
(peroxidase) 		4 PHE A 720
ALA A 716
GLY A 712
TYR A 711
 None
 1.01A 3bcrA-4c51A:
undetectable		 3bcrA-4c51A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cmf AMINOTRANSFERASE

([Nectria]
haematococca) 		PF01063
(Aminotran_4) 		4 PHE A   8
ALA A  12
GLY A  10
TYR A  11
 None
 1.16A 3bcrA-4cmfA:
undetectable		 3bcrA-4cmfA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d72 GLYCOSIDE HYDROLASE

(Streptococcus
pneumoniae) 		PF08306
(Glyco_hydro_98M)
PF08307
(Glyco_hydro_98C) 		4 ASN A 591
ALA A 595
GLY A 593
TYR A 560
 None
None
None
NAG  A2009 (-4.6A)
 1.06A 3bcrA-4d72A:
2.8		 3bcrA-4d72A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i3m AEROTAXIS TRANSDUCER
AER2

(Pseudomonas
aeruginosa) 		no annotation 4 PHE A 130
ALA A 124
GLY A 126
TYR A 125
 None
 1.02A 3bcrA-4i3mA:
undetectable		 3bcrA-4i3mA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lyp EXO-BETA-1,4-MANNOSI
DASE

(Rhizomucor
miehei) 		no annotation 4 ASN A 166
PHE A 169
ALA A 165
TYR A 126
 None
 1.07A 3bcrA-4lypA:
2.8		 3bcrA-4lypA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nuz ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F2

(Streptococcus
pyogenes) 		no annotation 4 ASN A 677
PHE A 666
GLY A 645
TYR A 644
 None
 1.12A 3bcrA-4nuzA:
2.0		 3bcrA-4nuzA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o5f TYPE III
PANTOTHENATE KINASE

(Burkholderia
thailandensis) 		PF03309
(Pan_kinase) 		4 ASN A  91
PHE A 139
ALA A  82
GLY A 100
 None
None
None
PAU  A 301 (-3.4A)
 1.06A 3bcrA-4o5fA:
undetectable		 3bcrA-4o5fA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A

(Pseudomonas
mendocina) 		PF02332
(Phenol_Hydrox) 		4 PHE A 155
ALA A 158
GLY A  98
TYR A  97
 None
 1.04A 3bcrA-4p1cA:
undetectable		 3bcrA-4p1cA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfw ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF00496
(SBP_bac_5) 		4 ASN A 432
PHE A 281
ALA A 433
GLY A 435
 None
None
BMA  A 606 ( 4.2A)
BMA  A 605 ( 3.6A)
 1.21A 3bcrA-4pfwA:
undetectable		 3bcrA-4pfwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2w PUTATIVE
ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE

(Streptococcus
pneumoniae) 		PF01832
(Glucosaminidase) 		4 ASN A 130
PHE A 134
ALA A 270
GLY A 266
 None
 1.18A 3bcrA-4q2wA:
undetectable		 3bcrA-4q2wA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qfe ENOYL-COA HYDRATASE

(Mycolicibacterium
smegmatis) 		PF00378
(ECH_1) 		4 ASN A 176
ALA A 175
GLY A 173
TYR A 170
 None
 1.14A 3bcrA-4qfeA:
undetectable		 3bcrA-4qfeA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rtf CHAPERONE PROTEIN
DNAK

(Mycobacterium
tuberculosis) 		PF00012
(HSP70) 		4 ASN D 123
PHE D 122
ALA D 125
GLY D  74
 None
 1.16A 3bcrA-4rtfD:
undetectable		 3bcrA-4rtfD:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ryb 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3

(Neisseria
meningitidis) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 ASN A 125
ALA A   4
GLY A 175
TYR A   3
 None
 1.18A 3bcrA-4rybA:
undetectable		 3bcrA-4rybA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u0t ADC-7 BETA-LACTAMASE

(Acinetobacter
baumannii) 		PF00144
(Beta-lactamase) 		4 ASN A  79
ALA A 251
GLY A  74
TYR A  76
 None
 1.07A 3bcrA-4u0tA:
undetectable		 3bcrA-4u0tA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uph SULFATASE (SULFURIC
ESTER HYDROLASE)
PROTEIN

(Agrobacterium
tumefaciens) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		4 PHE A  58
ALA A 330
GLY A 347
TYR A 349
 None
 1.13A 3bcrA-4uphA:
undetectable		 3bcrA-4uphA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE

(Burkholderia
cenocepacia) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 PHE A 292
ALA A 265
GLY A 258
TYR A 261
 None
 0.95A 3bcrA-4wjbA:
undetectable		 3bcrA-4wjbA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9n L-ALPHA-GLYCEROPHOSP
HATE OXIDASE

(Mycoplasma
pneumoniae) 		PF01266
(DAO) 		4 ASN A  66
ALA A 353
GLY A  69
TYR A  65
 None
 1.14A 3bcrA-4x9nA:
undetectable		 3bcrA-4x9nA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgc ORIGIN RECOGNITION
COMPLEX SUBUNIT 2
ORIGIN RECOGNITION
COMPLEX SUBUNIT 3

(Drosophila
melanogaster) 		PF04084
(ORC2)
PF07034
(ORC3_N) 		4 ASN B 484
PHE B 351
GLY C 317
TYR C 320
 None
 1.14A 3bcrA-4xgcB:
undetectable		 3bcrA-4xgcB:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yxd SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
CYTOCHROME B SMALL
SUBUNIT,
MITOCHONDRIAL

(Sus scrofa) 		PF05328
(CybS) 		4 ASN D 120
PHE D 119
GLY D 115
TYR D 118
 None
 1.17A 3bcrA-4yxdD:
undetectable		 3bcrA-4yxdD:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zvi DNA GYRASE SUBUNIT B

(Escherichia
coli) 		PF00204
(DNA_gyraseB)
PF02518
(HATPase_c) 		4 PHE A 225
ALA A 224
GLY A 221
TYR A 218
 None
 1.20A 3bcrA-4zviA:
undetectable		 3bcrA-4zviA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5af3 VAPBC49

(Mycobacterium
tuberculosis) 		PF04255
(DUF433) 		4 ASN A 182
ALA A 181
GLY A 179
TYR A 178
 None
 0.95A 3bcrA-5af3A:
undetectable		 3bcrA-5af3A:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c3j SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
CYTOCHROME B SMALL
SUBUNIT,
MITOCHONDRIAL

(Ascaris suum) 		PF05328
(CybS) 		4 ASN D 140
PHE D 139
GLY D 135
TYR D 138
 None
 1.18A 3bcrA-5c3jD:
3.1		 3bcrA-5c3jD:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ch8 MONO- AND
DIACYLGLYCEROL
LIPASE

(Penicillium
cyclopium) 		PF01764
(Lipase_3)
PF03893
(Lipase3_N) 		4 ASN A  40
ALA A 268
GLY A 269
TYR A  21
 None
None
None
CL  A 304 (-4.7A)
 1.17A 3bcrA-5ch8A:
undetectable		 3bcrA-5ch8A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e84 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo sapiens) 		PF00012
(HSP70) 		4 ASN A 177
PHE A 176
ALA A 179
GLY A 100
 None
 1.11A 3bcrA-5e84A:
undetectable		 3bcrA-5e84A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g4l OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY PROTEIN

(Clostridium sp.) 		PF13561
(adh_short_C2) 		4 PHE A 235
ALA A 239
GLY A 237
TYR A 238
 None
 1.16A 3bcrA-5g4lA:
4.8		 3bcrA-5g4lA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h4r BETA-1,3-1,4-GLUCANA
SE

(Caldicellulosiruptor
sp. F32) 		PF00150
(Cellulase) 		4 ASN A 362
PHE A 372
ALA A 364
GLY A 369
 CTT  A 401 (-4.0A)
CTT  A 401 ( 4.5A)
None
None
 1.10A 3bcrA-5h4rA:
undetectable		 3bcrA-5h4rA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hsi PUTATIVE
DECARBOXYLASE

(Lactobacillus
brevis) 		PF00282
(Pyridoxal_deC) 		4 ASN A 459
ALA A 337
GLY A 464
TYR A 463
 None
 1.01A 3bcrA-5hsiA:
3.5		 3bcrA-5hsiA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5itg SORBITOL
DEHYDROGENASE

(Gluconobacter
oxydans) 		PF01232
(Mannitol_dh)
PF08125
(Mannitol_dh_C) 		4 PHE A 202
ALA A 206
GLY A 204
TYR A 205
 None
 1.14A 3bcrA-5itgA:
undetectable		 3bcrA-5itgA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjo UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF08238
(Sel1) 		4 ASN A 188
ALA A 185
GLY A 183
TYR A 184
 None
 1.14A 3bcrA-5jjoA:
undetectable		 3bcrA-5jjoA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k9h 0940_GH29

(unidentified) 		PF00754
(F5_F8_type_C)
PF01120
(Alpha_L_fucos) 		4 ASN A 175
ALA A 174
GLY A 172
TYR A 171
 None
 0.90A 3bcrA-5k9hA:
undetectable		 3bcrA-5k9hA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kqi CATALASE-PEROXIDASE

(Burkholderia
pseudomallei) 		PF00141
(peroxidase) 		4 PHE A 728
ALA A 724
GLY A 720
TYR A 719
 None
 0.98A 3bcrA-5kqiA:
undetectable		 3bcrA-5kqiA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kx4 10.7 KDA SALIVARY
PROTEIN

(Lutzomyia
longipalpis) 		no annotation 4 ASN A  13
PHE A  10
ALA A  14
TYR A  79
 None
 1.04A 3bcrA-5kx4A:
undetectable		 3bcrA-5kx4A:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE DELTA
SUBUNIT

(Aromatoleum
aromaticum) 		PF02538
(Hydantoinase_B) 		4 ASN A 420
PHE A 438
ALA A 416
GLY A  61
 None
 1.21A 3bcrA-5l9wA:
undetectable		 3bcrA-5l9wA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mtv EH DOMAIN-CONTAINING
PROTEIN 4

(Mus musculus) 		PF00350
(Dynamin_N)
PF16880
(EHD_N) 		4 ASN A 137
ALA A 134
GLY A 132
TYR A 172
 None
 1.14A 3bcrA-5mtvA:
undetectable		 3bcrA-5mtvA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5obu CHAPERONE PROTEIN
DNAK

(Mycoplasma
genitalium) 		no annotation 4 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 None
 1.12A 3bcrA-5obuA:
2.0		 3bcrA-5obuA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5obw CHAPERONE PROTEIN
DNAK

(Mycoplasma
genitalium) 		no annotation 4 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 SO4  A 406 (-4.3A)
GOL  A 410 (-4.8A)
None
None
 1.14A 3bcrA-5obwA:
2.2		 3bcrA-5obwA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5pep PEPSIN

(Sus scrofa) 		PF00026
(Asp) 		4 ASN A 180
ALA A 324
GLY A 177
TYR A 175
 None
 1.05A 3bcrA-5pepA:
undetectable		 3bcrA-5pepA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uds LACTATE RACEMIZATION
OPERON PROTEIN LARE

(Lactobacillus
plantarum) 		PF02540
(NAD_synthase) 		4 ASN A 109
ALA A 142
GLY A 143
TYR A 105
 None
 1.15A 3bcrA-5udsA:
3.3		 3bcrA-5udsA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w8o HOMOSERINE
O-ACETYLTRANSFERASE

(Mycolicibacterium
hassiacum) 		PF00561
(Abhydrolase_1) 		4 PHE A 277
ALA A 279
GLY A 280
TYR A 282
 None
 1.19A 3bcrA-5w8oA:
3.6		 3bcrA-5w8oA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w8p HOMOSERINE
O-ACETYLTRANSFERASE

(Mycobacteroides
abscessus) 		PF00561
(Abhydrolase_1) 		4 PHE A 284
ALA A 286
GLY A 287
TYR A 289
 None
 1.20A 3bcrA-5w8pA:
2.5		 3bcrA-5w8pA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w8x LIPID-A-DISACCHARIDE
SYNTHASE

(Escherichia
coli) 		no annotation 4 ASN A 103
PHE A 102
ALA A  99
GLY A  14
 None
 0.78A 3bcrA-5w8xA:
6.2		 3bcrA-5w8xA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xbl CRISPR-ASSOCIATED
ENDONUCLEASE
CAS9/CSN1

(Streptococcus
pyogenes) 		PF13395
(HNH_4)
PF16592
(Cas9_REC)
PF16593
(Cas9-BH)
PF16595
(Cas9_PI) 		4 PHE A 351
ALA A 360
GLY A 358
TYR A 359
 G  B  43 ( 4.9A)
G  B  43 ( 3.4A)
None
G  B  43 ( 4.8A)
 0.86A 3bcrA-5xblA:
undetectable		 3bcrA-5xblA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y9d ACYL-COENZYME A
OXIDASE 1

(Yarrowia
lipolytica) 		no annotation 4 ASN A 428
PHE A 430
ALA A 636
GLY A 639
 None
 1.04A 3bcrA-5y9dA:
undetectable		 3bcrA-5y9dA:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ys9 ACYL-COENZYME A
OXIDASE 3

(Yarrowia
lipolytica) 		no annotation 4 ASN A 439
PHE A 441
ALA A 646
GLY A 649
 None
 0.98A 3bcrA-5ys9A:
2.0		 3bcrA-5ys9A:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus) 		no annotation 4 ASN A 177
PHE A 176
ALA A 179
GLY A 100
 None
 1.09A 3bcrA-6eoeA:
undetectable		 3bcrA-6eoeA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eti ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2

(Homo sapiens) 		no annotation 4 PHE A 341
ALA A 273
GLY A 275
TYR A 276
 None
 1.21A 3bcrA-6etiA:
undetectable		 3bcrA-6etiA:
7.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM

(Streptomyces
maritimus) 		no annotation 4 ASN A 375
ALA A 431
GLY A 433
TYR A 432
 None
 1.08A 3bcrA-6fydA:
undetectable		 3bcrA-6fydA:
8.86