SIMILAR PATTERNS OF AMINO ACIDS FOR 3BA0_A_HAEA477_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e9y UREASE SUBUNIT BETA

(Helicobacter
pylori) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		3 HIS B 282
GLU B 222
HIS B 248
 None
None
NI  B3001 ( 3.4A)
 0.78A 3ba0A-1e9yB:
undetectable		 3ba0A-1e9yB:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ef9 METHYLMALONYL COA
DECARBOXYLASE

(Escherichia
coli) 		PF00378
(ECH_1) 		3 HIS A 196
GLU A 200
HIS A 197
 None
 0.78A 3ba0A-1ef9A:
undetectable		 3ba0A-1ef9A:
20.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus scrofa) 		PF00045
(Hemopexin)
PF00413
(Peptidase_M10) 		3 HIS A 183
GLU A 219
HIS A 222
 ZN  A 997 (-3.2A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
 0.54A 3ba0A-1fblA:
31.4		 3ba0A-1fblA:
53.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hfs STROMELYSIN-1

(Homo sapiens) 		PF00413
(Peptidase_M10) 		3 HIS A 166
GLU A 202
HIS A 205
 ZN  A 258 ( 3.0A)
L04  A 256 ( 2.7A)
ZN  A 257 ( 3.2A)
 0.41A 3ba0A-1hfsA:
26.7		 3ba0A-1hfsA:
59.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hv5 STROMELYSIN 3

(Mus musculus) 		PF00413
(Peptidase_M10) 		3 HIS A 183
GLU A 220
HIS A 223
 ZN  A5501 (-3.6A)
RXP  A6001 (-3.0A)
ZN  A5502 (-3.4A)
 0.62A 3ba0A-1hv5A:
22.0		 3ba0A-1hv5A:
27.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1izo CYTOCHROME P450
152A1

(Bacillus
subtilis) 		PF00067
(p450) 		3 HIS A 220
GLU A 216
HIS A 215
 None
 0.87A 3ba0A-1izoA:
undetectable		 3ba0A-1izoA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis) 		PF12468
(TTSSLRR) 		3 HIS A1092
GLU A1094
HIS A1074
 None
 0.77A 3ba0A-1jl5A:
undetectable		 3ba0A-1jl5A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l6j MATRIX
METALLOPROTEINASE-9

(Homo sapiens) 		PF00040
(fn2)
PF00413
(Peptidase_M10)
PF01471
(PG_binding_1) 		3 HIS A 190
GLU A 402
HIS A 405
 ZN  A 501 (-3.4A)
ZN  A 500 ( 4.3A)
ZN  A 500 (-3.2A)
 0.52A 3ba0A-1l6jA:
22.1		 3ba0A-1l6jA:
26.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pba PROCARBOXYPEPTIDASE
B

(Sus scrofa) 		PF02244
(Propep_M14) 		3 HIS A   1
GLU A   5
HIS A   2
 None
 0.84A 3ba0A-1pbaA:
undetectable		 3ba0A-1pbaA:
12.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qib 72 KDA TYPE IV
COLLAGENASE

(Homo sapiens) 		PF00413
(Peptidase_M10) 		3 HIS A 166
GLU A 202
HIS A 205
 ZN  A 502 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
 0.55A 3ba0A-1qibA:
25.8		 3ba0A-1qibA:
38.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qjs HEMOPEXIN

(Oryctolagus
cuniculus) 		PF00045
(Hemopexin) 		3 HIS A 244
GLU A 130
HIS A 127
 None
 0.88A 3ba0A-1qjsA:
20.5		 3ba0A-1qjsA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rm8 MATRIX
METALLOPROTEINASE-16

(Homo sapiens) 		PF00413
(Peptidase_M10) 		3 HIS A 208
GLU A 247
HIS A 250
 ZN  A 501 (-3.2A)
BAT  A 800 (-2.7A)
ZN  A 500 ( 3.2A)
 0.55A 3ba0A-1rm8A:
25.5		 3ba0A-1rm8A:
26.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1slm STROMELYSIN-1

(Homo sapiens) 		PF00413
(Peptidase_M10)
PF01471
(PG_binding_1) 		3 HIS A 166
GLU A 202
HIS A 205
 ZN  A 258 ( 3.0A)
ZN  A 257 ( 4.1A)
ZN  A 257 ( 3.2A)
 0.39A 3ba0A-1slmA:
26.6		 3ba0A-1slmA:
30.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1twd COPPER HOMEOSTASIS
PROTEIN CUTC

(Shigella
flexneri) 		PF03932
(CutC) 		3 HIS A 121
GLU A  26
HIS A 196
 None
 0.76A 3ba0A-1twdA:
undetectable		 3ba0A-1twdA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u3d CRYPTOCHROME 1
APOPROTEIN

(Arabidopsis
thaliana) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		3 HIS A 255
GLU A 258
HIS A 253
 None
None
NDS  A 512 (-4.3A)
 0.75A 3ba0A-1u3dA:
undetectable		 3ba0A-1u3dA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6

(Homo sapiens) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		3 HIS A 213
GLU A 294
HIS A 301
 None
 0.87A 3ba0A-1xfdA:
3.7		 3ba0A-1xfdA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xss FLUORESCENT PROTEIN

(Favia favus) 		PF01353
(GFP) 		3 HIS A 215
GLU A 214
HIS A 196
 None
DYG  A  64 ( 3.7A)
DYG  A  64 ( 3.5A)
 0.85A 3ba0A-1xssA:
undetectable		 3ba0A-1xssA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2btj GREEN TO RED
PHOTOCONVERTIBLE
GPF-LIKE PROTEIN
EOSFP

(Lobophyllia
hemprichii) 		PF01353
(GFP) 		3 HIS A 213
GLU A 212
HIS A 194
 None
IEY  A  64 ( 3.6A)
IEY  A  64 ( 3.6A)
 0.82A 3ba0A-2btjA:
undetectable		 3ba0A-2btjA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dq7 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE FYN

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 HIS X 241
GLU X 237
HIS X 236
 None
 0.85A 3ba0A-2dq7X:
undetectable		 3ba0A-2dq7X:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2efl FORMIN-BINDING
PROTEIN 1

(Homo sapiens) 		PF00611
(FCH) 		3 HIS A 206
GLU A 203
HIS A 199
 None
 0.89A 3ba0A-2eflA:
undetectable		 3ba0A-2eflA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gw3 KAEDE

(Trachyphyllia
geoffroyi) 		PF01353
(GFP) 		3 HIS A 213
GLU A 212
HIS A 194
 None
CR8  A  63 ( 3.6A)
CR8  A  63 ( 3.6A)
 0.80A 3ba0A-2gw3A:
undetectable		 3ba0A-2gw3A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gw4 KAEDE

(Trachyphyllia
geoffroyi) 		PF01353
(GFP) 		3 HIS B 213
GLU B 212
HIS B 194
 None
RC7  B  63 ( 3.5A)
RC7  B  63 ( 3.6A)
 0.78A 3ba0A-2gw4B:
undetectable		 3ba0A-2gw4B:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i9w HYPOTHETICAL PROTEIN

(Psychrobacter
arcticus) 		PF02810
(SEC-C) 		3 HIS A 132
GLU A 133
HIS A 131
 None
 0.85A 3ba0A-2i9wA:
undetectable		 3ba0A-2i9wA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ick ISOPENTENYL-DIPHOSPH
ATE DELTA ISOMERASE

(Homo sapiens) 		PF00293
(NUDIX) 		3 HIS A 148
GLU A 147
HIS A  41
 None
MN  A 229 ( 2.0A)
MN  A 229 (-3.4A)
 0.67A 3ba0A-2ickA:
undetectable		 3ba0A-2ickA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j1d DISHEVELED-ASSOCIATE
D ACTIVATOR OF
MORPHOGENESIS 1

(Homo sapiens) 		PF02181
(FH2) 		3 HIS G 749
GLU G 750
HIS G 747
 None
 0.72A 3ba0A-2j1dG:
undetectable		 3ba0A-2j1dG:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j4b TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT
72/90-100 KDA

(Encephalitozoon
cuniculi) 		PF04494
(TFIID_NTD2) 		3 HIS A  96
GLU A  97
HIS A  94
 None
 0.81A 3ba0A-2j4bA:
undetectable		 3ba0A-2j4bA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jua DE NOVO PROTEIN S836

(unidentified) 		no annotation 3 HIS A  94
GLU A  98
HIS A  95
 None
 0.71A 3ba0A-2juaA:
undetectable		 3ba0A-2juaA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l09 ASR4154 PROTEIN

(Nostoc sp. PCC
7120) 		PF08369
(PCP_red) 		3 HIS A  57
GLU A  56
HIS A  60
 None
 0.62A 3ba0A-2l09A:
undetectable		 3ba0A-2l09A:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n4i SELECTION AND UPKEEP
OF INTRAEPITHELIAL
T-CELLS PROTEIN 1

(Mus musculus) 		PF07686
(V-set) 		3 HIS A 134
GLU A 133
HIS A 122
 None
 0.82A 3ba0A-2n4iA:
undetectable		 3ba0A-2n4iA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ogr FLUORESCENT PROTEIN
FP538

(Zoanthus sp.) 		PF01353
(GFP) 		3 HIS A 222
GLU A 221
HIS A 202
 None
CH7  A  66 ( 3.6A)
CH7  A  66 ( 3.4A)
 0.83A 3ba0A-2ogrA:
undetectable		 3ba0A-2ogrA:
20.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2oy4 NEUTROPHIL
COLLAGENASE

(Homo sapiens) 		PF00413
(Peptidase_M10) 		3 HIS A 162
GLU A 198
HIS A 201
 ZN  A 998 (-3.3A)
ZN  A 999 ( 4.4A)
ZN  A 999 (-3.4A)
 0.52A 3ba0A-2oy4A:
26.8		 3ba0A-2oy4A:
53.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pny ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
2

(Homo sapiens) 		PF00293
(NUDIX) 		3 HIS A 147
GLU A 146
HIS A  40
 None
MN  A 229 (-1.9A)
MN  A 229 (-3.3A)
 0.68A 3ba0A-2pnyA:
undetectable		 3ba0A-2pnyA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pxs GFP-LIKE FLUORESCENT
CHROMOPROTEIN FP506

(Zoanthus sp.) 		PF01353
(GFP) 		3 HIS A 222
GLU A 221
HIS A 202
 None
DYG  A  66 ( 3.5A)
DYG  A  66 ( 3.2A)
 0.82A 3ba0A-2pxsA:
undetectable		 3ba0A-2pxsA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qed HYDROXYACYLGLUTATHIO
NE HYDROLASE

(Salmonella
enterica) 		PF00753
(Lactamase_B)
PF16123
(HAGH_C) 		3 HIS A 114
GLU A  79
HIS A  54
 None
 0.82A 3ba0A-2qedA:
undetectable		 3ba0A-2qedA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rdy BH0842 PROTEIN

(Bacillus
halodurans) 		PF14498
(Glyco_hyd_65N_2) 		3 HIS A 456
GLU A 383
HIS A 460
 None
 0.89A 3ba0A-2rdyA:
undetectable		 3ba0A-2rdyA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vzx GREEN FLUORESCENT
PROTEIN

(Dendronephthya
sp. SSAL-2002) 		PF01353
(GFP) 		3 HIS A 212
GLU A 211
HIS A 193
 None
CR8  A  64 ( 3.6A)
CR8  A  64 ( 3.5A)
 0.76A 3ba0A-2vzxA:
undetectable		 3ba0A-2vzxA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wlt L-ASPARAGINASE

(Helicobacter
pylori) 		PF00710
(Asparaginase) 		3 HIS A 110
GLU A 206
HIS A 203
 None
 0.88A 3ba0A-2wltA:
undetectable		 3ba0A-2wltA:
21.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2y6c MATRILYSIN

(Homo sapiens) 		PF00413
(Peptidase_M10) 		3 HIS A 183
GLU A 220
HIS A 223
 ZN  A1266 ( 3.3A)
TQI  A1269 (-2.9A)
ZN  A1267 ( 3.3A)
 0.43A 3ba0A-2y6cA:
23.8		 3ba0A-2y6cA:
54.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yhe SEC-ALKYL SULFATASE

(Pseudomonas sp.
DSM 6611) 		PF00753
(Lactamase_B)
PF14863
(Alkyl_sulf_dimr)
PF14864
(Alkyl_sulf_C) 		3 HIS A 213
GLU A 217
HIS A 181
 None
None
ZN  A 701 ( 3.3A)
 0.84A 3ba0A-2yheA:
undetectable		 3ba0A-2yheA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yp1 AROMATIC
PEROXYGENASE

(Agrocybe
aegerita) 		PF01328
(Peroxidase_2) 		3 HIS A 138
GLU A 122
HIS A 118
 SO4  A1329 ( 4.7A)
MG  A 353 ( 2.9A)
None
 0.87A 3ba0A-2yp1A:
undetectable		 3ba0A-2yp1A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zo4 METALLO-BETA-LACTAMA
SE FAMILY PROTEIN

(Thermus
thermophilus) 		PF00753
(Lactamase_B) 		3 HIS A 175
GLU A  95
HIS A  71
 None
 0.72A 3ba0A-2zo4A:
undetectable		 3ba0A-2zo4A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxo N,N-DIMETHYLTRANSFER
ASE

(Streptomyces
venezuelae) 		PF13649
(Methyltransf_25) 		3 HIS A 168
GLU A 179
HIS A 181
 None
 0.87A 3ba0A-3bxoA:
undetectable		 3ba0A-3bxoA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c10 HISTONE DEACETYLASE
7A

(Homo sapiens) 		PF00850
(Hist_deacetyl) 		3 HIS A 806
GLU A 804
HIS A 814
 None
 0.66A 3ba0A-3c10A:
undetectable		 3ba0A-3c10A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c7o ENDO-1,4-BETA-XYLANA
SE

(Bacillus
subtilis) 		PF03422
(CBM_6)
PF04616
(Glyco_hydro_43) 		3 HIS A 248
GLU A 256
HIS A 274
 None
 0.86A 3ba0A-3c7oA:
5.9		 3ba0A-3c7oA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ce2 PUTATIVE PEPTIDASE

(Chlamydia
abortus) 		PF01432
(Peptidase_M3)
PF08439
(Peptidase_M3_N) 		3 HIS A 481
GLU A 485
HIS A 482
 None
None
ZN  A 701 (-3.4A)
 0.88A 3ba0A-3ce2A:
undetectable		 3ba0A-3ce2A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f43 PUTATIVE ANTI-SIGMA
FACTOR ANTAGONIST
TM1081

(Thermotoga
maritima) 		PF01740
(STAS) 		3 HIS A  -2
GLU A  34
HIS A  -1
 None
 0.88A 3ba0A-3f43A:
undetectable		 3ba0A-3f43A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fjv UNCHARACTERIZED
NOVEL PROTEIN

(Burkholderia
pseudomallei) 		PF12007
(DUF3501) 		3 HIS A  55
GLU A  56
HIS A  22
 None
 0.83A 3ba0A-3fjvA:
undetectable		 3ba0A-3fjvA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdo UNCHARACTERIZED
OXIDOREDUCTASE YVAA

(Bacillus
subtilis) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		3 HIS A 131
GLU A 333
HIS A 196
 None
 0.77A 3ba0A-3gdoA:
undetectable		 3ba0A-3gdoA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hww 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE

(Escherichia
coli) 		PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
PF16582
(TPP_enzyme_M_2) 		3 HIS A 496
GLU A 498
HIS A 499
 None
 0.71A 3ba0A-3hwwA:
undetectable		 3ba0A-3hwwA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY

(Aeromonas
hydrophila) 		PF00106
(adh_short) 		3 HIS A  61
GLU A  62
HIS A  60
 None
 0.79A 3ba0A-3l6eA:
undetectable		 3ba0A-3l6eA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lcz INHIBITOR OF TRAP,
REGULATED BY T-BOX
(TRP) SEQUENCE RTPA

(Bacillus
licheniformis) 		PF15777
(Anti-TRAP) 		3 HIS A  52
GLU A  53
HIS A  50
 None
 0.84A 3ba0A-3lczA:
undetectable		 3ba0A-3lczA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lgg ADENOSINE DEAMINASE
CECR1

(Homo sapiens) 		PF00962
(A_deaminase)
PF08451
(A_deaminase_N) 		3 HIS A  59
GLU A 168
HIS A 166
 None
 0.83A 3ba0A-3lggA:
undetectable		 3ba0A-3lggA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lgg ADENOSINE DEAMINASE
CECR1

(Homo sapiens) 		PF00962
(A_deaminase)
PF08451
(A_deaminase_N) 		3 HIS A 301
GLU A 182
HIS A 267
 None
CFE  A 513 (-3.0A)
CFE  A 513 (-3.9A)
 0.81A 3ba0A-3lggA:
undetectable		 3ba0A-3lggA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n29 CARBOXYNORSPERMIDINE
DECARBOXYLASE

(Campylobacter
jejuni) 		PF00278
(Orn_DAP_Arg_deC) 		3 HIS A  79
GLU A 233
HIS A 164
 None
PLP  A1001 (-3.5A)
PLP  A1001 ( 4.8A)
 0.78A 3ba0A-3n29A:
undetectable		 3ba0A-3n29A:
21.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o2x COLLAGENASE 3

(Homo sapiens) 		PF00413
(Peptidase_M10) 		3 HIS A1187
GLU A1223
HIS A1226
 ZN  A1998 ( 3.2A)
3O2  A1801 (-2.7A)
ZN  A1999 ( 3.4A)
 0.56A 3ba0A-3o2xA:
26.3		 3ba0A-3o2xA:
56.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3os6 ISOCHORISMATE
SYNTHASE DHBC

(Bacillus
anthracis) 		PF00425
(Chorismate_bind) 		3 HIS A 242
GLU A 241
HIS A 240
 None
 0.82A 3ba0A-3os6A:
undetectable		 3ba0A-3os6A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pja TRANSLIN

(Homo sapiens) 		PF01997
(Translin) 		3 HIS A  90
GLU A  89
HIS A  88
 None
 0.86A 3ba0A-3pjaA:
undetectable		 3ba0A-3pjaA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3px2 N-METHYLTRANSFERASE

(Streptomyces
fradiae) 		PF13649
(Methyltransf_25) 		3 HIS A 180
GLU A 191
HIS A 193
 None
 0.89A 3ba0A-3px2A:
undetectable		 3ba0A-3px2A:
18.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3shi INTERSTITIAL
COLLAGENASE

(Homo sapiens) 		PF00413
(Peptidase_M10) 		3 HIS A 183
GLU A 219
HIS A 222
 ZN  A 302 (-3.1A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.4A)
 0.53A 3ba0A-3shiA:
26.7		 3ba0A-3shiA:
58.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tk3 CYTOCHROME P450 2B4

(Oryctolagus
cuniculus) 		PF00067
(p450) 		3 HIS A 354
GLU A 355
HIS A 412
 None
 0.84A 3ba0A-3tk3A:
undetectable		 3ba0A-3tk3A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		3 HIS A 134
GLU A 133
HIS A 115
 None
ACT  A 443 (-2.7A)
CRK  A 214 (-3.4A)
 0.87A 3ba0A-3u0kA:
undetectable		 3ba0A-3u0kA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uaj ENVELOPE PROTEIN

(Dengue virus) 		no annotation 3 HIS B  27
GLU B  26
HIS B 282
 None
 0.89A 3ba0A-3uajB:
undetectable		 3ba0A-3uajB:
18.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3v96 STROMELYSIN-2

(Homo sapiens) 		PF00413
(Peptidase_M10) 		3 HIS B 182
GLU B 218
HIS B 221
 ZN  B 302 (-3.2A)
ZN  B 301 ( 3.9A)
ZN  B 301 (-3.3A)
 0.38A 3ba0A-3v96B:
27.2		 3ba0A-3v96B:
57.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w0l GLUCOKINASE
REGULATORY PROTEIN

(Xenopus laevis) 		no annotation 3 HIS B  70
GLU B  64
HIS B  72
 None
 0.64A 3ba0A-3w0lB:
undetectable		 3ba0A-3w0lB:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zul FLUORESCENT PROTEIN
DRONPA

(Echinophyllia
sp. SC22) 		PF01353
(GFP) 		3 HIS A 212
GLU A 211
HIS A 193
 None
GYC  A  63 ( 3.5A)
GYC  A  63 ( 3.3A)
 0.89A 3ba0A-3zulA:
undetectable		 3ba0A-3zulA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ad9 BETA-LACTAMASE-LIKE
PROTEIN 2

(Homo sapiens) 		PF00753
(Lactamase_B) 		3 HIS A 259
GLU A 255
HIS A 254
 None
 0.89A 3ba0A-4ad9A:
undetectable		 3ba0A-4ad9A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bc6 SERINE/THREONINE-PRO
TEIN KINASE 10

(Homo sapiens) 		PF00069
(Pkinase) 		3 HIS A 238
GLU A 239
HIS A 237
 None
 0.80A 3ba0A-4bc6A:
undetectable		 3ba0A-4bc6A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bed HEMOCYANIN KLH1

(Megathura
crenulata) 		PF00264
(Tyrosinase)
PF14830
(Haemocyan_bet_s) 		3 HIS A1094
GLU A1098
HIS A1099
 None
 0.81A 3ba0A-4bedA:
undetectable		 3ba0A-4bedA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bed HEMOCYANIN KLH1

(Megathura
crenulata) 		PF00264
(Tyrosinase)
PF14830
(Haemocyan_bet_s) 		3 HIS B2917
GLU B2921
HIS B2918
 None
 0.82A 3ba0A-4bedB:
undetectable		 3ba0A-4bedB:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c22 L-FUCOSE ISOMERASE

(Streptococcus
pneumoniae) 		PF02952
(Fucose_iso_C)
PF07881
(Fucose_iso_N1)
PF07882
(Fucose_iso_N2) 		3 HIS A 291
GLU A 204
HIS A 290
 None
 0.73A 3ba0A-4c22A:
undetectable		 3ba0A-4c22A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d7q RALF,
PROLINE/BETAINE
TRANSPORTER

(Legionella
pneumophila;
Rickettsia
prowazekii) 		PF01369
(Sec7) 		3 HIS A   2
GLU A  41
HIS A   1
 None
 0.87A 3ba0A-4d7qA:
undetectable		 3ba0A-4d7qA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dxo LEA X(6) GFP-LIKE
PROTEINS

(synthetic
construct) 		PF01353
(GFP) 		3 HIS A 212
GLU A 211
HIS A 193
 None
CR8  A  63 ( 4.0A)
CR8  A  63 ( 3.4A)
 0.79A 3ba0A-4dxoA:
undetectable		 3ba0A-4dxoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fq7 MALEATE CIS-TRANS
ISOMERASE

(Pseudomonas
putida) 		no annotation 3 HIS A  91
GLU A 154
HIS A  94
 None
 0.79A 3ba0A-4fq7A:
3.3		 3ba0A-4fq7A:
19.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gr8 MACROPHAGE
METALLOELASTASE

(Homo sapiens) 		PF00413
(Peptidase_M10) 		3 HIS A 183
GLU A 219
HIS A 222
 ZN  A 302 (-3.2A)
R4C  A 306 (-2.7A)
ZN  A 301 ( 3.2A)
 0.55A 3ba0A-4gr8A:
26.7		 3ba0A-4gr8A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4in9 KARILYSIN PROTEASE

(Tannerella
forsythia) 		PF00413
(Peptidase_M10) 		3 HIS A 117
GLU A 156
HIS A 159
 ZN  A 302 (-3.2A)
ZN  A 301 ( 4.2A)
ZN  A 301 (-3.3A)
 0.48A 3ba0A-4in9A:
21.8		 3ba0A-4in9A:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oue PUTATIVE LIPOPROTEIN

(Bacteroides
thetaiotaomicron) 		PF00754
(F5_F8_type_C)
PF01120
(Alpha_L_fucos) 		3 HIS A 154
GLU A 153
HIS A 152
 None
 0.83A 3ba0A-4oueA:
undetectable		 3ba0A-4oueA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oy4 CHIMERA PROTEIN OF
CALMODULIN, GPF-LIKE
PROTEIN EOSFP, AND
MYOSIN LIGHT CHAIN
KINASE

(Gallus gallus;
Lobophyllia
hemprichii;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		3 HIS A 220
GLU A 219
HIS A 201
 GOL  A 503 (-3.8A)
CR8  A 303 ( 3.6A)
CR8  A 303 ( 3.8A)
 0.77A 3ba0A-4oy4A:
undetectable		 3ba0A-4oy4A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r9x COPPER HOMEOSTASIS
PROTEIN CUTC

(Bacillus
anthracis) 		PF03932
(CutC) 		3 HIS A 119
GLU A  24
HIS A 197
 PGE  A 301 (-3.3A)
None
None
 0.90A 3ba0A-4r9xA:
undetectable		 3ba0A-4r9xA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s28 PHOSPHOMETHYLPYRIMID
INE SYNTHASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF01964
(ThiC_Rad_SAM) 		3 HIS A 266
GLU A 267
HIS A 264
 None
 0.87A 3ba0A-4s28A:
undetectable		 3ba0A-4s28A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u90 GEPHYRIN

(Rattus
norvegicus) 		PF00994
(MoCF_biosynth)
PF03453
(MoeA_N)
PF03454
(MoeA_C) 		3 HIS A 682
GLU A 684
HIS A 681
 None
 0.88A 3ba0A-4u90A:
3.5		 3ba0A-4u90A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ufc GH95

(Bacteroides
ovatus) 		PF14498
(Glyco_hyd_65N_2) 		3 HIS A 451
GLU A 383
HIS A 455
 None
 0.85A 3ba0A-4ufcA:
undetectable		 3ba0A-4ufcA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uyr FLOCCULATION PROTEIN
FLO11

(Saccharomyces
cerevisiae) 		PF10182
(Flo11) 		3 HIS A   5
GLU A  33
HIS A   8
 None
None
PO4  A1210 (-3.8A)
 0.80A 3ba0A-4uyrA:
undetectable		 3ba0A-4uyrA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wxx DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Homo sapiens) 		PF00145
(DNA_methylase)
PF01426
(BAH)
PF02008
(zf-CXXC)
PF12047
(DNMT1-RFD) 		3 HIS A1460
GLU A1480
HIS A1459
 None
 0.76A 3ba0A-4wxxA:
undetectable		 3ba0A-4wxxA:
13.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9

(Homo sapiens) 		PF00413
(Peptidase_M10) 		3 HIS A 190
GLU A 227
HIS A 230
 ZN  A 303 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
 0.48A 3ba0A-4xctA:
26.1		 3ba0A-4xctA:
50.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z8w MAJOR POLLEN
ALLERGEN PLA L 1

(Plantago
lanceolata) 		PF01190
(Pollen_Ole_e_I) 		3 HIS A  10
GLU A  12
HIS A 116
 None
 0.79A 3ba0A-4z8wA:
undetectable		 3ba0A-4z8wA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5do7 ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
8

(Homo sapiens) 		PF00005
(ABC_tran)
PF01061
(ABC2_membrane) 		3 HIS B 504
GLU B 503
HIS B 420
 None
 0.76A 3ba0A-5do7B:
undetectable		 3ba0A-5do7B:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5exc GREEN FLUORESCENT
PROTEIN

(Dendronephthya
sp. SSAL-2002) 		PF01353
(GFP) 		3 HIS I 212
GLU I 211
HIS I 193
 None
RC7  I  64 ( 3.4A)
RC7  I  64 ( 3.6A)
 0.83A 3ba0A-5excI:
undetectable		 3ba0A-5excI:
19.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5h0u MATRIX
METALLOPROTEINASE-14

(Homo sapiens) 		PF00413
(Peptidase_M10) 		3 HIS A 201
GLU A 240
HIS A 243
 ZN  A 303 (-3.2A)
GOL  A 311 (-4.2A)
ZN  A 302 (-3.4A)
 0.39A 3ba0A-5h0uA:
25.6		 3ba0A-5h0uA:
31.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l1t PENTALENOLACTONE
SYNTHASE

(Streptomyces
arenae) 		PF00067
(p450) 		3 HIS A 118
GLU A 122
HIS A 119
 None
 0.76A 3ba0A-5l1tA:
undetectable		 3ba0A-5l1tA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III

(Bacteroides
thetaiotaomicron) 		no annotation 3 HIS A 117
GLU A 123
HIS A 118
 None
 0.89A 3ba0A-5na7A:
undetectable		 3ba0A-5na7A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ofk GLYCOSIDE HYDROLASE
FAMILY 48

(Caldicellulosiruptor
bescii) 		PF00331
(Glyco_hydro_10) 		3 HIS A 211
GLU A 243
HIS A 245
 None
 0.85A 3ba0A-5ofkA:
undetectable		 3ba0A-5ofkA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5th6 MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9

(Homo sapiens) 		PF00413
(Peptidase_M10)
PF01471
(PG_binding_1) 		3 HIS A 190
GLU A 402
HIS A 405
 ZN  A 502 (-3.2A)
ZN  A 501 ( 4.2A)
ZN  A 501 (-3.2A)
 0.49A 3ba0A-5th6A:
22.1		 3ba0A-5th6A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE

(environmental
samples) 		PF00202
(Aminotran_3) 		3 HIS A 203
GLU A 204
HIS A 201
 None
 0.85A 3ba0A-5uc7A:
undetectable		 3ba0A-5uc7A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uj8 ORIGIN RECOGNITION
COMPLEX SUBUNIT 3

(Homo sapiens) 		PF07034
(ORC3_N) 		3 HIS A 586
GLU A 590
HIS A 591
 None
 0.80A 3ba0A-5uj8A:
undetectable		 3ba0A-5uj8A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wh8 PUTATIVE
CARBOHYDRATE-ACTIVE
ENZYME

(uncultured
organism) 		no annotation 3 HIS A 366
GLU A  51
HIS A 369
 None
 0.86A 3ba0A-5wh8A:
undetectable		 3ba0A-5wh8A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xhm FERRITIN, MIDDLE
SUBUNIT

(Rana
catesbeiana) 		PF00210
(Ferritin) 		3 HIS A  56
GLU A  57
HIS A  54
 None
MG  A 201 (-2.6A)
None
 0.82A 3ba0A-5xhmA:
undetectable		 3ba0A-5xhmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xvd HYDROGENASE-2 SMALL
CHAIN

(Citrobacter sp.
MGH106) 		no annotation 3 HIS S 194
GLU S 193
HIS S 192
 None
None
SF4  S 401 (-3.2A)
 0.83A 3ba0A-5xvdS:
undetectable		 3ba0A-5xvdS:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yj6 DOCKERIN TYPE I
REPEAT-CONTAINING
PROTEIN

(Ruminiclostridium
thermocellum) 		no annotation 3 HIS A 646
GLU A 647
HIS A 642
 None
 0.85A 3ba0A-5yj6A:
undetectable		 3ba0A-5yj6A:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6en9 HYDROGENASE-2 SMALL
CHAIN

(Escherichia
coli) 		no annotation 3 HIS S 194
GLU S 193
HIS S 192
 None
None
SF4  S 301 (-3.1A)
 0.83A 3ba0A-6en9S:
undetectable		 3ba0A-6en9S:
14.65