SIMILAR PATTERNS OF AMINO ACIDS FOR 3B9M_A_SALA1200_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bbj IGG4-KAPPA B72.3 FAB
(HEAVY CHAIN)

(Homo sapiens;
Mus musculus) 		no annotation 4 ILE H  34
HIS H  35
TYR H  27
GLY H 102
 None
 1.29A 3b9mA-1bbjH:
undetectable		 3b9mA-1bbjH:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1crk CREATINE KINASE

(Gallus gallus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ILE A  88
HIS A  92
TYR A  77
GLY A 283
 None
 1.20A 3b9mA-1crkA:
0.0		 3b9mA-1crkA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fmm ACIDIC FIBROBLAST
GROWTH FACTOR

(Notophthalmus
viridescens) 		PF00167
(FGF) 		4 ILE S 103
TYR S   7
ARG S  27
GLY S  11
 None
 1.16A 3b9mA-1fmmS:
undetectable		 3b9mA-1fmmS:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fnh PROTEIN
(FIBRONECTIN)

(Homo sapiens) 		PF00041
(fn3) 		4 ILE A 240
TYR A 249
ARG A 225
GLY A 242
 None
 1.21A 3b9mA-1fnhA:
undetectable		 3b9mA-1fnhA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nox NADH OXIDASE

(Thermus
thermophilus) 		PF00881
(Nitroreductase) 		4 ILE A 100
HIS A 101
ARG A 108
GLY A 103
 None
 1.11A 3b9mA-1noxA:
undetectable		 3b9mA-1noxA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nsv GALACTOSE MUTAROTASE

(Lactococcus
lactis) 		PF01263
(Aldose_epim) 		4 ILE A 102
HIS A 103
TYR A 133
GLY A  98
 None
 1.25A 3b9mA-1nsvA:
undetectable		 3b9mA-1nsvA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o94 TRIMETHYLAMINE
DEHYDROGENASE

(Methylophilus
methylotrophus) 		PF00724
(Oxidored_FMN)
PF07992
(Pyr_redox_2) 		4 ILE A 681
HIS A 427
ARG A 444
GLY A 398
 None
ADP  A1731 (-3.8A)
None
ADP  A1731 (-3.4A)
 1.18A 3b9mA-1o94A:
0.0		 3b9mA-1o94A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p50 ARGININE KINASE

(Limulus
polyphemus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ILE A  86
HIS A  90
TYR A  75
GLY A 276
 None
 1.07A 3b9mA-1p50A:
1.1		 3b9mA-1p50A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qh4 CREATINE KINASE

(Gallus gallus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ILE A  93
HIS A  97
TYR A  82
GLY A 288
 None
 1.16A 3b9mA-1qh4A:
1.1		 3b9mA-1qh4A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qk1 CREATINE KINASE,
UBIQUITOUS
MITOCHONDRIAL

(Homo sapiens) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ILE A  88
HIS A  92
TYR A  77
GLY A 283
 None
 1.14A 3b9mA-1qk1A:
0.0		 3b9mA-1qk1A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sdd COAGULATION FACTOR V

(Bos taurus) 		PF00754
(F5_F8_type_C)
PF07732
(Cu-oxidase_3) 		4 ILE B1798
HIS B1799
ARG B1796
GLY B1793
 None
 1.19A 3b9mA-1sddB:
undetectable		 3b9mA-1sddB:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t1s 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE

(Escherichia
coli) 		PF02670
(DXP_reductoisom)
PF08436
(DXP_redisom_C)
PF13288
(DXPR_C) 		4 HIS A 208
TYR A 314
ARG A 190
GLY A 184
 SO4  A1001 (-3.8A)
None
None
SO4  A1001 (-3.2A)
 1.31A 3b9mA-1t1sA:
0.0		 3b9mA-1t1sA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u6r CREATINE KINASE, M
CHAIN

(Oryctolagus
cuniculus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ILE A  92
HIS A  96
TYR A  81
GLY A 287
 None
 1.22A 3b9mA-1u6rA:
1.1		 3b9mA-1u6rA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uwi BETA-GALACTOSIDASE

(Sulfolobus
solfataricus) 		PF00232
(Glyco_hydro_1) 		4 ILE A 145
TYR A 143
ARG A 420
GLY A 421
 None
 1.10A 3b9mA-1uwiA:
0.0		 3b9mA-1uwiA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vcj NEURAMINIDASE

(Influenza B
virus) 		PF00064
(Neur) 		4 ILE A 114
HIS A 134
ARG A 147
GLY A 145
 None
 1.21A 3b9mA-1vcjA:
undetectable		 3b9mA-1vcjA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrp CREATINE KINASE, M
CHAIN

(Tetronarce
californica) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ILE A  93
HIS A  97
TYR A  82
GLY A 288
 None
 1.28A 3b9mA-1vrpA:
undetectable		 3b9mA-1vrpA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wle SERYL-TRNA
SYNTHETASE

(Bos taurus) 		PF00587
(tRNA-synt_2b) 		4 ILE A 445
HIS A 188
ARG A 398
GLY A 395
 None
 1.24A 3b9mA-1wleA:
3.7		 3b9mA-1wleA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x94 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE

(Vibrio cholerae) 		PF13580
(SIS_2) 		4 ILE A 171
HIS A 175
ARG A 161
GLY A 122
 None
 1.02A 3b9mA-1x94A:
undetectable		 3b9mA-1x94A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z5v TUBULIN GAMMA-1
CHAIN

(Homo sapiens) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		4 ILE A 141
HIS A 139
ARG A 194
GLY A 148
 None
 0.87A 3b9mA-1z5vA:
undetectable		 3b9mA-1z5vA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j1q ARGININE KINASE

(Trypanosoma
cruzi) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ILE A  86
HIS A  90
TYR A  75
GLY A 276
 None
 1.12A 3b9mA-2j1qA:
undetectable		 3b9mA-2j1qA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lob GOLGI-ASSOCIATED PDZ
AND COILED-COIL
MOTIF-CONTAINING
PROTEIN

(Homo sapiens) 		PF00595
(PDZ) 		4 ILE A  60
HIS A  61
ARG A  68
GLY A  63
 None
 1.27A 3b9mA-2lobA:
undetectable		 3b9mA-2lobA:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lul TYROSINE-PROTEIN
KINASE TEC

(Homo sapiens) 		PF00169
(PH)
PF00779
(BTK) 		4 ILE A  64
HIS A  94
TYR A  50
ARG A  60
 None
 1.27A 3b9mA-2lulA:
undetectable		 3b9mA-2lulA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ocp DEOXYGUANOSINE
KINASE

(Homo sapiens) 		PF01712
(dNK) 		4 ILE A 231
HIS A 232
TYR A 191
GLY A 224
 None
 1.14A 3b9mA-2ocpA:
undetectable		 3b9mA-2ocpA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pq6 UDP-GLUCURONOSYL/UDP
-GLUCOSYLTRANSFERASE

(Medicago
truncatula) 		PF00201
(UDPGT) 		4 ILE A  39
HIS A  33
ARG A  35
GLY A  36
 None
 1.26A 3b9mA-2pq6A:
undetectable		 3b9mA-2pq6A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pv2 CHAPERONE SURA

(Escherichia
coli) 		PF00639
(Rotamase) 		4 ILE A 242
HIS A 266
ARG A 260
GLY A 262
 None
 1.24A 3b9mA-2pv2A:
undetectable		 3b9mA-2pv2A:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pyj DNA POLYMERASE

(Bacillus virus
phi29) 		PF03175
(DNA_pol_B_2) 		4 ILE A 442
TYR A 315
ARG A 227
GLY A 229
 None
 1.17A 3b9mA-2pyjA:
undetectable		 3b9mA-2pyjA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qiw PEP PHOSPHONOMUTASE

(Corynebacterium
glutamicum) 		PF13714
(PEP_mutase) 		4 ILE A 208
HIS A 216
TYR A 185
GLY A 188
 None
None
SO4  A 255 ( 4.3A)
None
 1.26A 3b9mA-2qiwA:
undetectable		 3b9mA-2qiwA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2taa TAKA-AMYLASE A

(Aspergillus
oryzae) 		PF00128
(Alpha-amylase)
PF09260
(DUF1966) 		4 ILE A  62
TYR A  94
ARG A  18
GLY A  81
 None
 1.29A 3b9mA-2taaA:
undetectable		 3b9mA-2taaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uv8 FATTY ACID SYNTHASE
SUBUNIT BETA (FAS1)

(Saccharomyces
cerevisiae) 		PF00698
(Acyl_transf_1)
PF01575
(MaoC_dehydratas)
PF08354
(DUF1729)
PF13452
(MaoC_dehydrat_N)
PF16073
(SAT) 		4 ILE G 843
HIS G1055
ARG G 736
GLY G 738
 None
None
None
FMN  G3051 (-3.6A)
 1.31A 3b9mA-2uv8G:
undetectable		 3b9mA-2uv8G:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA

(Desulfovibrio
vulgaris) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 HIS A 266
TYR B 327
ARG B 336
GLY B 138
 None
None
SH0  A 503 (-3.0A)
None
 0.98A 3b9mA-2v4jA:
undetectable		 3b9mA-2v4jA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vd5 DMPK PROTEIN

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 183
HIS A 187
ARG A 324
GLY A 326
 None
 1.10A 3b9mA-2vd5A:
undetectable		 3b9mA-2vd5A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vd9 ALANINE RACEMASE

(Bacillus
anthracis) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 ILE A 362
HIS A  47
TYR A 359
GLY A 226
 None
None
EPC  A1395 ( 4.2A)
IN5  A1394 ( 3.2A)
 1.29A 3b9mA-2vd9A:
undetectable		 3b9mA-2vd9A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsz RUVB-LIKE 1

(Homo sapiens) 		PF06068
(TIP49) 		4 ILE A 271
HIS A 259
ARG A 273
GLY A  84
 None
 1.29A 3b9mA-2xszA:
undetectable		 3b9mA-2xszA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xzo REGULATOR OF
NONSENSE TRANSCRIPTS
1

(Homo sapiens) 		PF04851
(ResIII)
PF13086
(AAA_11)
PF13087
(AAA_12) 		4 ILE A 381
TYR A 344
ARG A 341
GLY A 336
 None
 1.30A 3b9mA-2xzoA:
2.3		 3b9mA-2xzoA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y9e MYOSIN-2

(Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		4 ILE X 280
TYR X 426
ARG X 267
GLY X 226
 None
 0.99A 3b9mA-2y9eX:
3.0		 3b9mA-2y9eX:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z55 ARCHAERHODOPSIN-2

(Halobacterium
sp. AUS-2) 		PF01036
(Bac_rhodopsin) 		4 ILE A 234
TYR A  47
ARG A 230
GLY A 225
 None
 0.93A 3b9mA-2z55A:
2.2		 3b9mA-2z55A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afl OLIGO ALGINATE LYASE

(Agrobacterium
fabrum) 		PF07940
(Hepar_II_III)
PF16332
(DUF4962) 		4 ILE A 550
HIS A 715
ARG A 567
GLY A 421
 None
 1.27A 3b9mA-3aflA:
undetectable		 3b9mA-3aflA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aty PROSTAGLANDIN F2A
SYNTHASE

(Trypanosoma
cruzi) 		PF00724
(Oxidored_FMN) 		4 ILE A 100
HIS A  94
ARG A 245
GLY A 188
 None
 1.31A 3b9mA-3atyA:
undetectable		 3b9mA-3atyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjz PHOSPHOHEPTOSE
ISOMERASE

(Pseudomonas
aeruginosa) 		PF13580
(SIS_2) 		4 ILE A 173
HIS A 177
ARG A 164
GLY A 122
 None
 1.06A 3b9mA-3bjzA:
undetectable		 3b9mA-3bjzA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxp PUTATIVE
LIPASE/ESTERASE

(Lactobacillus
plantarum) 		PF07859
(Abhydrolase_3) 		4 ILE A 150
HIS A 147
TYR A 212
GLY A 127
 None
 0.90A 3b9mA-3bxpA:
undetectable		 3b9mA-3bxpA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cih PUTATIVE
ALPHA-RHAMNOSIDASE

(Bacteroides
thetaiotaomicron) 		PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C) 		4 ILE A 286
HIS A 280
TYR A 196
GLY A 193
 None
 1.25A 3b9mA-3cihA:
undetectable		 3b9mA-3cihA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Bordetella
bronchiseptica) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ILE A 360
TYR A 171
ARG A 345
GLY A 336
 None
 1.11A 3b9mA-3ddmA:
undetectable		 3b9mA-3ddmA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dkm E3 UBIQUITIN-PROTEIN
LIGASE HECTD1

(Homo sapiens) 		PF06701
(MIB_HERC2) 		4 ILE A1312
HIS A1308
ARG A1325
GLY A1310
 None
 1.31A 3b9mA-3dkmA:
undetectable		 3b9mA-3dkmA:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dy5 ALLENE OXIDE
SYNTHASE-LIPOXYGENAS
E PROTEIN

(Plexaura
homomalla) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 ILE A 238
TYR A 167
ARG A 236
GLY A   7
 None
 1.14A 3b9mA-3dy5A:
1.9		 3b9mA-3dy5A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eni BACTERIOCHLOROPHYLL
A PROTEIN

(Chlorobaculum
tepidum) 		PF02327
(BChl_A) 		4 ILE A 235
HIS A 226
TYR A 123
ARG A 198
 None
BCL  A 376 (-3.4A)
BCL  A 378 (-4.6A)
None
 1.25A 3b9mA-3eniA:
undetectable		 3b9mA-3eniA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eoj BACTERIOCHLOROPHYLL
A PROTEIN

(Prosthecochloris
aestuarii) 		PF02327
(BChl_A) 		4 ILE A 236
HIS A 227
TYR A 123
ARG A 199
 None
BCL  A 376 (-3.5A)
BCL  A 378 (-4.6A)
EDO  A 379 ( 3.5A)
 1.23A 3b9mA-3eojA:
undetectable		 3b9mA-3eojA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ewm UNCHARACTERIZED
SUGAR KINASE PH1459

(Pyrococcus
horikoshii) 		PF00294
(PfkB) 		4 ILE A  15
HIS A  31
ARG A 283
GLY A 284
 None
 1.07A 3b9mA-3ewmA:
undetectable		 3b9mA-3ewmA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hgo 12-OXOPHYTODIENOATE
REDUCTASE 3

(Solanum
lycopersicum) 		PF00724
(Oxidored_FMN) 		4 ILE A 103
HIS A  97
ARG A 233
GLY A 178
 None
 1.31A 3b9mA-3hgoA:
undetectable		 3b9mA-3hgoA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrd NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT

(Eubacterium
barkeri) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 ILE A 144
HIS A 145
ARG A  97
GLY A 307
 None
 1.25A 3b9mA-3hrdA:
undetectable		 3b9mA-3hrdA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3itw PROTEIN TIOX

(Micromonospora
sp. ML1) 		PF00903
(Glyoxalase) 		4 ILE A  46
HIS A   0
ARG A  24
GLY A  43
 None
 1.13A 3b9mA-3itwA:
undetectable		 3b9mA-3itwA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jq3 LOMBRICINE KINASE

(Urechis caupo) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ILE A  80
HIS A  84
TYR A  69
GLY A 275
 None
 1.06A 3b9mA-3jq3A:
undetectable		 3b9mA-3jq3A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ju5 ARGININE KINASE

(Apostichopus
japonicus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ILE A  84
HIS A  88
TYR A  73
GLY A 279
 None
 1.21A 3b9mA-3ju5A:
undetectable		 3b9mA-3ju5A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpd ACIDIC EXTRACELLULAR
SUBTILISIN-LIKE
PROTEASE APRV2

(Dichelobacter
nodosus) 		PF00082
(Peptidase_S8) 		4 ILE A 254
HIS A 108
TYR A  14
GLY A 111
 None
 1.26A 3b9mA-3lpdA:
undetectable		 3b9mA-3lpdA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mf9 ENDO-1,4-BETA-XYLANA
SE

(Thermopolyspora
flexuosa) 		PF00457
(Glyco_hydro_11) 		4 ILE A 150
HIS A 155
TYR A  64
ARG A 141
 None
 1.24A 3b9mA-3mf9A:
undetectable		 3b9mA-3mf9A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pay PUTATIVE ADHESIN

(Bacteroides
ovatus) 		PF08842
(Mfa2) 		4 ILE A 275
HIS A 325
TYR A 267
GLY A 317
 None
 1.17A 3b9mA-3payA:
undetectable		 3b9mA-3payA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qdk RIBULOKINASE

(Bacillus
halodurans) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 ILE A 392
HIS A 535
ARG A 427
GLY A 425
 None
 1.28A 3b9mA-3qdkA:
undetectable		 3b9mA-3qdkA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qfi TRANSCRIPTIONAL
REGULATOR

(Enterococcus
faecalis) 		PF03816
(LytR_cpsA_psr) 		4 ILE A 170
TYR A 195
ARG A 211
GLY A 208
 None
 1.23A 3b9mA-3qfiA:
undetectable		 3b9mA-3qfiA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qfv CDC42BPB PROTEIN

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 188
HIS A 192
ARG A 327
GLY A 329
 None
 1.03A 3b9mA-3qfvA:
undetectable		 3b9mA-3qfvA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3slg PBGP3 PROTEIN

(Burkholderia
pseudomallei) 		PF01370
(Epimerase) 		4 ILE A 237
HIS A 114
TYR A 250
GLY A 247
 None
 1.28A 3b9mA-3slgA:
undetectable		 3b9mA-3slgA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ti7 BASIC EXTRACELLULAR
SUBTILISIN-LIKE
PROTEASE BPRV

(Dichelobacter
nodosus) 		PF00082
(Peptidase_S8) 		4 ILE A 254
HIS A 108
TYR A  14
GLY A 111
 None
 1.29A 3b9mA-3ti7A:
undetectable		 3b9mA-3ti7A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vth HYDROGENASE
MATURATION FACTOR

(Caldanaerobacter
subterraneus) 		PF00708
(Acylphosphatase)
PF01300
(Sua5_yciO_yrdC)
PF07503
(zf-HYPF) 		4 ILE A 737
HIS A 487
TYR A 465
GLY A 510
 None
FE  A 807 ( 3.4A)
None
AP2  A 806 ( 4.8A)
 1.05A 3b9mA-3vthA:
undetectable		 3b9mA-3vthA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vzm ENDO-1,4-BETA-XYLANA
SE

(Bacillus
circulans) 		PF00457
(Glyco_hydro_11) 		4 ILE A 144
HIS A 149
TYR A  53
ARG A 132
 None
 1.25A 3b9mA-3vzmA:
undetectable		 3b9mA-3vzmA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w77 FMN-DEPENDENT
NADH-AZOREDUCTASE

(Bacillus sp.
B29) 		PF02525
(Flavodoxin_2) 		4 ILE A 193
HIS A 183
ARG A 144
GLY A 146
 None
FMN  A 301 (-4.1A)
None
FMN  A 301 (-3.6A)
 1.20A 3b9mA-3w77A:
undetectable		 3b9mA-3w77A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zse ENDO-1,4-BETA-XYLANA
SE

(Thermobifida
fusca) 		PF00457
(Glyco_hydro_11) 		4 ILE A 189
HIS A 194
TYR A 103
ARG A 180
 None
 1.20A 3b9mA-3zseA:
undetectable		 3b9mA-3zseA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a8x RNA-BINDING PROTEIN
WITH SERINE-RICH
DOMAIN 1

(Homo sapiens) 		PF00076
(RRM_1) 		4 ILE A 165
HIS A 164
ARG A 167
GLY A 204
 None
 0.91A 3b9mA-4a8xA:
undetectable		 3b9mA-4a8xA:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aw2 SERINE/THREONINE-PRO
TEIN KINASE MRCK
ALPHA

(Rattus
norvegicus) 		PF00069
(Pkinase)
PF00433
(Pkinase_C) 		4 ILE A 189
HIS A 193
ARG A 328
GLY A 330
 None
 1.07A 3b9mA-4aw2A:
undetectable		 3b9mA-4aw2A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b5m PUTATIVE
EXODEOXYRIBONUCLEASE

(Neisseria
meningitidis) 		PF03372
(Exo_endo_phos) 		4 ILE A 183
HIS A 184
TYR A 222
ARG A 193
 None
 1.26A 3b9mA-4b5mA:
undetectable		 3b9mA-4b5mA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b6g PUTATIVE ESTERASE

(Neisseria
meningitidis) 		PF00756
(Esterase) 		4 ILE A 263
HIS A 266
TYR A 256
GLY A 143
 None
 1.27A 3b9mA-4b6gA:
undetectable		 3b9mA-4b6gA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b9a PROBABLE EPOXIDE
HYDROLASE

(Pseudomonas
aeruginosa) 		PF00561
(Abhydrolase_1) 		4 HIS A 106
TYR A  67
ARG A 108
GLY A 109
 None
None
SO4  A1312 (-4.0A)
None
 1.01A 3b9mA-4b9aA:
undetectable		 3b9mA-4b9aA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bhl ARGININE KINASE

(Litopenaeus
vannamei) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ILE A  86
HIS A  90
TYR A  75
GLY A 276
 None
 1.17A 3b9mA-4bhlA:
undetectable		 3b9mA-4bhlA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bi8 RAP1A

(Serratia
marcescens) 		no annotation 4 ILE A 112
TYR A  64
ARG A 107
GLY A  43
 None
 0.97A 3b9mA-4bi8A:
3.0		 3b9mA-4bi8A:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cpn NEURAMINIDASE

(Influenza B
virus) 		PF00064
(Neur) 		4 ILE A 113
HIS A 133
ARG A 146
GLY A 144
 None
 1.09A 3b9mA-4cpnA:
undetectable		 3b9mA-4cpnA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g3a CLIP-ASSOCIATING
PROTEIN

(Drosophila
melanogaster) 		PF12348
(CLASP_N) 		4 ILE A  96
HIS A 139
ARG A  98
GLY A 100
 None
 1.26A 3b9mA-4g3aA:
undetectable		 3b9mA-4g3aA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hz8 BETA-GLUCOSIDASE

(uncultured
bacterium) 		PF00232
(Glyco_hydro_1) 		4 ILE A 362
HIS A 414
ARG A 407
GLY A 409
 None
 1.31A 3b9mA-4hz8A:
undetectable		 3b9mA-4hz8A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0r PUTATIVE GLYCOSIDE
HYDROLASE

(Bacteroides
vulgatus) 		PF13204
(DUF4038)
PF16586
(DUF5060) 		4 ILE A 377
HIS A 389
ARG A 420
GLY A 135
 None
 1.28A 3b9mA-4n0rA:
undetectable		 3b9mA-4n0rA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 ILE A 120
HIS A  90
ARG A 118
GLY A  46
 None
 1.23A 3b9mA-4n5fA:
2.3		 3b9mA-4n5fA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n82 RIBONUCLEOTIDE
REDUCTASE

(Streptococcus
sanguinis) 		no annotation 4 ILE B   9
HIS B  39
TYR B  64
GLY B  13
 None
None
FMN  B 201 ( 4.3A)
FMN  B 201 (-3.9A)
 1.04A 3b9mA-4n82B:
undetectable		 3b9mA-4n82B:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		4 HIS A 934
TYR A 972
ARG A 929
GLY A 932
 None
 1.18A 3b9mA-4pj6A:
2.1		 3b9mA-4pj6A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rf7 ARGININE KINASE

(Anthopleura
japonica) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ILE A  90
HIS A  94
TYR A  79
GLY A 280
 None
 1.21A 3b9mA-4rf7A:
1.2		 3b9mA-4rf7A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ryk LMO0325 PROTEIN

(Listeria
monocytogenes) 		PF01381
(HTH_3) 		4 ILE A  54
TYR A  23
ARG A   9
GLY A   5
 None
 1.01A 3b9mA-4rykA:
3.2		 3b9mA-4rykA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tqo METHANOL
DEHYDROGENASE
PROTEIN, LARGE
SUBUNIT

(Methylococcus
capsulatus) 		no annotation 4 ILE B 424
HIS B 540
ARG B 137
GLY B 498
 None
None
PQQ  B 702 (-3.0A)
None
 1.27A 3b9mA-4tqoB:
undetectable		 3b9mA-4tqoB:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4woe TAUROCYAMINE KINASE

(Schistosoma
mansoni) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ILE A 444
HIS A 448
TYR A 433
GLY A 636
 None
 1.27A 3b9mA-4woeA:
undetectable		 3b9mA-4woeA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis) 		no annotation 4 ILE A 147
TYR A  75
ARG A  92
GLY A 137
 None
INS  A 301 (-3.8A)
None
None
 1.25A 3b9mA-4xf7A:
undetectable		 3b9mA-4xf7A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a2r ANGIOTENSIN-CONVERTI
NG ENZYME

(Drosophila
melanogaster) 		PF01401
(Peptidase_M2) 		4 ILE A 254
HIS A 232
ARG A 240
GLY A 252
 None
 1.18A 3b9mA-5a2rA:
undetectable		 3b9mA-5a2rA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d0f UNCHARACTERIZED
PROTEIN

([Candida]
glabrata) 		PF06202
(GDE_C)
PF14699
(hGDE_N)
PF14701
(hDGE_amylase)
PF14702
(hGDE_central) 		4 ILE A1081
TYR A1436
ARG A1084
GLY A1513
 None
 1.18A 3b9mA-5d0fA:
3.8		 3b9mA-5d0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h42 UNCHARACTERIZED
PROTEIN

(Lachnoclostridium
phytofermentans) 		PF17167
(Glyco_hydro_36) 		4 ILE A 927
HIS A 924
ARG A1013
GLY A 635
 None
 1.26A 3b9mA-5h42A:
3.5		 3b9mA-5h42A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h42 UNCHARACTERIZED
PROTEIN

(Lachnoclostridium
phytofermentans) 		PF17167
(Glyco_hydro_36) 		4 ILE A 927
HIS A 924
ARG A1013
GLY A1009
 None
 1.09A 3b9mA-5h42A:
3.5		 3b9mA-5h42A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h5m ALPHA-CATENIN-LIKE
PROTEIN HMP-1

(Caenorhabditis
elegans) 		PF01044
(Vinculin) 		4 ILE A 283
HIS A 366
TYR A 345
GLY A 361
 None
 1.21A 3b9mA-5h5mA:
4.3		 3b9mA-5h5mA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l46 DIMETHYLGLYCINE
DEHYDROGENASE,
MITOCHONDRIAL

(Homo sapiens) 		PF01266
(DAO)
PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF16350
(FAO_M) 		4 ILE A 402
HIS A 403
TYR A 116
GLY A 406
 FAD  A 901 (-4.6A)
None
None
None
 1.23A 3b9mA-5l46A:
undetectable		 3b9mA-5l46A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mz8 ALDEHYDE
DEHYDROGENASE 21

(Physcomitrella
patens) 		PF00171
(Aldedh) 		4 ILE A 397
HIS A 304
ARG A 307
GLY A 270
 None
None
PEG  A 512 ( 4.8A)
PEG  A 512 (-3.5A)
 1.27A 3b9mA-5mz8A:
undetectable		 3b9mA-5mz8A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5swn FLUOROACETATE
DEHALOGENASE

(Rhodopseudomonas
palustris) 		PF00561
(Abhydrolase_1) 		4 HIS A 109
TYR A  68
ARG A 111
GLY A 112
 None
None
FAH  A 401 (-3.8A)
None
 1.00A 3b9mA-5swnA:
undetectable		 3b9mA-5swnA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u8e ARGININE KINASE

(Polybetes
pythagoricus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ILE A  86
HIS A  90
TYR A  75
GLY A 276
 None
 1.17A 3b9mA-5u8eA:
1.0		 3b9mA-5u8eA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5urb METHIONINE--TRNA
LIGASE

(Acinetobacter
baumannii) 		PF08264
(Anticodon_1)
PF09334
(tRNA-synt_1g) 		4 ILE A  17
HIS A  18
TYR A  25
GLY A  20
 None
 1.25A 3b9mA-5urbA:
2.1		 3b9mA-5urbA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)

(Paraburkholderia
xenovorans) 		PF00982
(Glyco_transf_20) 		4 ILE A  14
HIS A 139
ARG A 458
GLY A  35
 None
None
ACT  A 506 (-4.3A)
None
 1.22A 3b9mA-5v0tA:
undetectable		 3b9mA-5v0tA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wdx JFH-1 NS3

(Hepacivirus C) 		no annotation 4 ILE A 336
HIS A 333
ARG A 467
GLY A 468
 None
 1.26A 3b9mA-5wdxA:
undetectable		 3b9mA-5wdxA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xd2 NUDIX FAMILY PROTEIN

(Mycolicibacterium
smegmatis) 		PF00293
(NUDIX)
PF00300
(His_Phos_1) 		4 ILE A 275
TYR A 315
ARG A 296
GLY A 298
 None
GOL  A 403 (-4.8A)
None
None
 1.10A 3b9mA-5xd2A:
undetectable		 3b9mA-5xd2A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z5d BETA-XYLOSIDASE

(Geobacillus
thermoleovorans) 		no annotation 4 ILE A 292
HIS A 226
ARG A 257
GLY A 255
 None
 1.12A 3b9mA-5z5dA:
undetectable		 3b9mA-5z5dA:
7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b3b APRA
METHYLTRANSFERASE 1

(Moorea
bouillonii) 		no annotation 4 ILE A 559
TYR A 614
ARG A 573
GLY A 571
 None
 1.06A 3b9mA-6b3bA:
undetectable		 3b9mA-6b3bA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ccz SERINE
HYDROXYMETHYLTRANSFE
RASE

(Medicago
truncatula) 		no annotation 4 ILE A 420
TYR A 399
ARG A 482
GLY A 480
 None
 1.15A 3b9mA-6cczA:
3.3		 3b9mA-6cczA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g1i -

(-) 		no annotation 4 ILE A 261
TYR A 230
ARG A 268
GLY A 266
 None
None
None
OHI  A 264 ( 4.4A)
 1.24A 3b9mA-6g1iA:
undetectable		 3b9mA-6g1iA:
undetectable