SIMILAR PATTERNS OF AMINO ACIDS FOR 3B9M_A_SALA1100

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dk5 ANNEXIN 24(CA32)

(Capsicum annuum) 		PF00191
(Annexin) 		4 LEU A 317
ARG A 257
LEU A 256
ALA A 300
 None
 1.07A 3b9mA-1dk5A:
0.6		 3b9mA-1dk5A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dvk PRP18

(Saccharomyces
cerevisiae) 		PF02840
(Prp18) 		4 LEU A 147
ARG A 235
LEU A 236
ALA A 142
 None
 1.12A 3b9mA-1dvkA:
undetectable		 3b9mA-1dvkA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gvh FLAVOHEMOPROTEIN

(Escherichia
coli) 		PF00042
(Globin)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		4 LEU A 208
ARG A 153
LEU A 245
ALA A 181
 None
 1.18A 3b9mA-1gvhA:
2.1		 3b9mA-1gvhA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kij DNA GYRASE SUBUNIT B

(Thermus
thermophilus) 		PF00204
(DNA_gyraseB)
PF02518
(HATPase_c) 		4 LEU A 293
ARG A 377
LEU A 376
ALA A 370
 None
 1.07A 3b9mA-1kijA:
0.0		 3b9mA-1kijA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kt9 DIADENOSINE
TETRAPHOSPHATE
HYDROLASE

(Caenorhabditis
elegans) 		PF00293
(NUDIX) 		4 LEU A  74
ARG A 129
LEU A 128
ALA A 122
 None
 1.16A 3b9mA-1kt9A:
undetectable		 3b9mA-1kt9A:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n11 ANKYRIN

(Homo sapiens) 		PF00023
(Ank)
PF12796
(Ank_2)
PF13637
(Ank_4)
PF13857
(Ank_5) 		4 LEU A 507
ARG A 550
LEU A 554
ALA A 543
 None
 1.09A 3b9mA-1n11A:
undetectable		 3b9mA-1n11A:
21.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		4 LEU A 219
ARG A 257
LEU A 260
ALA A 291
 None
DKA  A1003 (-4.1A)
None
CIT  A2001 ( 3.9A)
 0.57A 3b9mA-1tf0A:
38.0		 3b9mA-1tf0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v6h DIVALENT CATION
TOLERANCE PROTEIN
CUTA1

(Thermus
thermophilus) 		PF03091
(CutA1) 		4 LEU A  55
ARG A  70
LEU A  67
ALA A  21
 None
 1.14A 3b9mA-1v6hA:
undetectable		 3b9mA-1v6hA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vcg ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE

(Thermus
thermophilus) 		PF01070
(FMN_dh) 		4 LEU A 282
ARG A 311
LEU A 314
ALA A  59
 None
 0.95A 3b9mA-1vcgA:
undetectable		 3b9mA-1vcgA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vhi EPSTEIN BARR VIRUS
NUCLEAR ANTIGEN-1

(Human
gammaherpesvirus
4) 		PF02905
(EBV-NA1) 		4 LEU A 575
ARG A 521
LEU A 520
ALA A 525
 None
 1.14A 3b9mA-1vhiA:
undetectable		 3b9mA-1vhiA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wiw GLUCOSE-6-PHOSPHATE
ISOMERASE LIKE
PROTEIN

(Thermus
thermophilus) 		PF10432
(bact-PGI_C) 		4 LEU A  24
ARG A 185
LEU A 182
ALA A 110
 None
 1.08A 3b9mA-1wiwA:
undetectable		 3b9mA-1wiwA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wz8 ENOYL-COA HYDRATASE

(Thermus
thermophilus) 		PF00378
(ECH_1) 		4 LEU A  12
ARG A  47
LEU A  49
ALA A  43
 None
 1.19A 3b9mA-1wz8A:
undetectable		 3b9mA-1wz8A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ys7 TRANSCRIPTIONAL
REGULATORY PROTEIN
PRRA

(Mycobacterium
tuberculosis) 		PF00072
(Response_reg)
PF00486
(Trans_reg_C) 		4 LEU A 142
ARG A 149
LEU A 160
ALA A 169
 None
 1.18A 3b9mA-1ys7A:
undetectable		 3b9mA-1ys7A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yzg ADP-RIBOSYLATION
FACTOR-LIKE 8

(Homo sapiens) 		PF00025
(Arf) 		4 LEU A  89
ARG A  98
LEU A  99
ALA A  27
 None
None
None
GDP  A 181 (-4.0A)
 1.21A 3b9mA-1yzgA:
undetectable		 3b9mA-1yzgA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a1f URIDYLATE KINASE

(Haemophilus
influenzae) 		PF00696
(AA_kinase) 		4 LEU A  52
ARG A  33
LEU A  31
ALA A  17
 None
 1.03A 3b9mA-2a1fA:
undetectable		 3b9mA-2a1fA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b7n PROBABLE
NICOTINATE-NUCLEOTID
E PYROPHOSPHORYLASE

(Helicobacter
pylori) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		4 LEU A 162
ARG A 176
LEU A 155
ALA A 203
 None
 1.06A 3b9mA-2b7nA:
undetectable		 3b9mA-2b7nA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2chp METALLOREGULATION
DNA-BINDING STRESS
PROTEIN

(Bacillus
subtilis) 		PF00210
(Ferritin) 		4 LEU A 148
ARG A  33
LEU A  31
ALA A 103
 None
 1.06A 3b9mA-2chpA:
2.1		 3b9mA-2chpA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cwa SINGLE-STRAND
BINDING PROTEIN

(Thermus
thermophilus) 		PF00436
(SSB) 		4 LEU A 223
ARG A 189
LEU A 137
ALA A 186
 None
 1.07A 3b9mA-2cwaA:
undetectable		 3b9mA-2cwaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g37 PROLINE
DEHYDROGENASE/DELTA-
1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE

(Thermus
thermophilus) 		PF01619
(Pro_dh) 		4 LEU A 132
ARG A 117
LEU A 120
ALA A 149
 None
 1.19A 3b9mA-2g37A:
undetectable		 3b9mA-2g37A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gsc PUTATIVE
UNCHARACTERIZED
PROTEIN XCC0516

(Xanthomonas
campestris) 		PF05635
(23S_rRNA_IVP) 		4 LEU A  14
ARG A 124
LEU A 122
ALA A 117
 None
 1.12A 3b9mA-2gscA:
3.8		 3b9mA-2gscA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hay PUTATIVE
NAD(P)H-FLAVIN
OXIDOREDUCTASE

(Streptococcus
pyogenes) 		PF00881
(Nitroreductase) 		4 LEU A 117
ARG A 104
LEU A 103
ALA A  97
 None
 1.15A 3b9mA-2hayA:
2.4		 3b9mA-2hayA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i6e HYPOTHETICAL PROTEIN

(Deinococcus
radiodurans) 		PF02621
(VitK2_biosynth) 		4 LEU A 190
ARG A 125
LEU A 124
ALA A 118
 None
 1.11A 3b9mA-2i6eA:
undetectable		 3b9mA-2i6eA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ja2 GLUTAMYL-TRNA
SYNTHETASE

(Mycobacterium
tuberculosis) 		PF00749
(tRNA-synt_1c) 		4 LEU A 187
ARG A 234
LEU A 232
ALA A 227
 None
 1.19A 3b9mA-2ja2A:
undetectable		 3b9mA-2ja2A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT

(Acinetobacter
baumannii) 		PF02771
(Acyl-CoA_dh_N)
PF08028
(Acyl-CoA_dh_2) 		4 LEU A 324
ARG A 351
LEU A 408
ALA A 355
 None
 1.13A 3b9mA-2jbrA:
undetectable		 3b9mA-2jbrA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jmr FIMF

(Escherichia
coli) 		PF00419
(Fimbrial) 		4 LEU A  96
ARG A 173
LEU A  30
ALA A 146
 None
 1.12A 3b9mA-2jmrA:
undetectable		 3b9mA-2jmrA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okx RHAMNOSIDASE B

(Bacillus sp.
GL1) 		PF05592
(Bac_rhamnosid)
PF08531
(Bac_rhamnosid_N)
PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C) 		4 LEU A 111
ARG A   4
LEU A  42
ALA A   8
 None
 1.18A 3b9mA-2okxA:
undetectable		 3b9mA-2okxA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q0z PROTEIN PRO2281

(Homo sapiens) 		PF02889
(Sec63) 		4 LEU X  92
ARG X 253
LEU X 109
ALA X 139
 None
 0.97A 3b9mA-2q0zX:
undetectable		 3b9mA-2q0zX:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r6i UNCHARACTERIZED
PROTEIN ATU1473

(Agrobacterium
fabrum) 		PF07542
(ATP12) 		4 LEU A 189
ARG A 117
LEU A 116
ALA A 110
 None
 1.15A 3b9mA-2r6iA:
undetectable		 3b9mA-2r6iA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uun C-PHYCOCYANIN

(Leptolyngbya
sp.) 		PF00502
(Phycobilisome) 		4 LEU B 105
ARG B 114
LEU B 113
ALA B 169
 None
None
CYC  B 184 (-3.9A)
None
 1.20A 3b9mA-2uunB:
2.4		 3b9mA-2uunB:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uyo HYPOTHETICAL PROTEIN
ML2640

(Mycobacterium
leprae) 		PF04072
(LCM) 		4 LEU A 189
ARG A 268
LEU A 266
ALA A 260
 None
 1.21A 3b9mA-2uyoA:
undetectable		 3b9mA-2uyoA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x1i 4-ALPHA-GLUCANOTRANS
FERASE

(Thermus
brockianus) 		PF02446
(Glyco_hydro_77) 		4 LEU A 324
ARG A 281
LEU A 280
ALA A 331
 None
 1.20A 3b9mA-2x1iA:
undetectable		 3b9mA-2x1iA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywo PROBABLE
THIOL-DISULFIDE
ISOMERASE/THIOREDOXI
N

(Thermus
thermophilus) 		PF00578
(AhpC-TSA) 		4 LEU A 122
ARG A 159
LEU A 158
ALA A 152
 None
 1.00A 3b9mA-2ywoA:
undetectable		 3b9mA-2ywoA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aii GLUTAMYL-TRNA
SYNTHETASE

(Methanothermobacter
thermautotrophicus) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		4 LEU A 133
ARG A 356
LEU A 109
ALA A 153
 None
EDO  A 602 ( 4.4A)
None
EDO  A 602 ( 4.7A)
 0.98A 3b9mA-3aiiA:
undetectable		 3b9mA-3aiiA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bq9 PREDICTED ROSSMANN
FOLD
NUCLEOTIDE-BINDING
DOMAIN-CONTAINING
PROTEIN

(Idiomarina
baltica) 		PF03641
(Lysine_decarbox)
PF11892
(DUF3412)
PF14793
(DUF4478) 		4 LEU A 264
ARG A 336
LEU A 349
ALA A 245
 None
 1.09A 3b9mA-3bq9A:
undetectable		 3b9mA-3bq9A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e2j ATP SYNTHASE SUBUNIT
S, MITOCHONDRIAL

(Bos taurus) 		no annotation 4 LEU A  83
ARG A  32
LEU A  30
ALA A  25
 None
 1.11A 3b9mA-3e2jA:
undetectable		 3b9mA-3e2jA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e8o UNCHARACTERIZED
PROTEIN WITH
FERREDOXIN-LIKE FOLD

(Deinococcus
radiodurans) 		PF03992
(ABM) 		4 LEU A  95
ARG A  36
LEU A  39
ALA A  27
 None
 1.20A 3b9mA-3e8oA:
2.4		 3b9mA-3e8oA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3enk UDP-GLUCOSE
4-EPIMERASE

(Burkholderia
pseudomallei) 		PF16363
(GDP_Man_Dehyd) 		4 LEU A 178
ARG A 255
LEU A 253
ALA A 248
 None
 1.09A 3b9mA-3enkA:
undetectable		 3b9mA-3enkA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fut DIMETHYLADENOSINE
TRANSFERASE

(Thermus
thermophilus) 		PF00398
(RrnaAD) 		4 LEU A 267
ARG A 242
LEU A 241
ALA A 235
 None
 1.17A 3b9mA-3futA:
undetectable		 3b9mA-3futA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lsz GLUTATHIONE
S-TRANSFERASE

(Rhodobacter
sphaeroides) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 LEU A 149
ARG A 200
LEU A 198
ALA A 193
 None
 1.16A 3b9mA-3lszA:
undetectable		 3b9mA-3lszA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8l 6-PHOSPHOFRUCTOKINAS
E, MUSCLE TYPE

(Oryctolagus
cuniculus) 		PF00365
(PFK) 		4 LEU A 546
ARG A 746
LEU A 586
ALA A 581
 None
 1.15A 3b9mA-3o8lA:
undetectable		 3b9mA-3o8lA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus) 		PF02626
(CT_A_B)
PF02682
(CT_C_D) 		4 LEU A  46
ARG A  30
LEU A  29
ALA A  23
 None
 1.10A 3b9mA-3oepA:
undetectable		 3b9mA-3oepA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q9v DNA-BINDING RESPONSE
REGULATOR

(Deinococcus
radiodurans) 		PF00486
(Trans_reg_C) 		4 LEU A 131
ARG A 138
LEU A 149
ALA A 158
 None
 1.21A 3b9mA-3q9vA:
undetectable		 3b9mA-3q9vA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rsc CALG2

(Micromonospora
echinospora) 		PF04101
(Glyco_tran_28_C) 		4 LEU A 104
ARG A 395
LEU A 393
ALA A 388
 None
 1.16A 3b9mA-3rscA:
undetectable		 3b9mA-3rscA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rsc CALG2

(Micromonospora
echinospora) 		PF04101
(Glyco_tran_28_C) 		4 LEU A 276
ARG A 284
LEU A 264
ALA A 271
 None
 0.99A 3b9mA-3rscA:
undetectable		 3b9mA-3rscA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t5t PUTATIVE
GLYCOSYLTRANSFERASE

(Streptomyces
hygroscopicus) 		PF00982
(Glyco_transf_20) 		4 LEU A 313
ARG A 419
LEU A 375
ALA A 438
 None
 1.10A 3b9mA-3t5tA:
undetectable		 3b9mA-3t5tA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t66 NICKEL ABC
TRANSPORTER
(NICKEL-BINDING
PROTEIN)

(Bacillus
halodurans) 		PF00496
(SBP_bac_5) 		4 LEU A 100
ARG A 391
LEU A 137
ALA A 109
 None
 0.90A 3b9mA-3t66A:
undetectable		 3b9mA-3t66A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ucq AMYLOSUCRASE

(Deinococcus
geothermalis) 		PF00128
(Alpha-amylase) 		4 LEU A 504
ARG A 478
LEU A 479
ALA A 463
 None
 0.88A 3b9mA-3ucqA:
3.0		 3b9mA-3ucqA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v7n THREONINE SYNTHASE

(Burkholderia
thailandensis) 		PF00291
(PALP)
PF14821
(Thr_synth_N) 		4 LEU A 456
ARG A  90
LEU A 123
ALA A 452
 None
 1.19A 3b9mA-3v7nA:
1.3		 3b9mA-3v7nA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wky PROPHENOLOXIDASE B

(Marsupenaeus
japonicus) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 LEU A 204
ARG A 141
LEU A 134
ALA A 110
 None
 1.11A 3b9mA-3wkyA:
undetectable		 3b9mA-3wkyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyx AMINE OXIDASE
[FLAVIN-CONTAINING]
B

(Homo sapiens) 		PF01593
(Amino_oxidase) 		4 LEU A 225
ARG A  70
LEU A  75
ALA A  18
 None
 1.14A 3b9mA-3zyxA:
undetectable		 3b9mA-3zyxA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0h ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE

(Arabidopsis
thaliana) 		PF00202
(Aminotran_3)
PF13500
(AAA_26) 		4 LEU A 801
ARG A 734
LEU A 746
ALA A 743
 None
 1.05A 3b9mA-4a0hA:
2.5		 3b9mA-4a0hA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ac0 TETRACYCLINE
REPRESSOR PROTEIN
CLASS B FROM
TRANSPOSON TN1 0

(Escherichia
coli) 		PF00440
(TetR_N)
PF02909
(TetR_C) 		4 LEU A  14
ARG A  49
LEU A  51
ALA A  56
 None
 1.16A 3b9mA-4ac0A:
4.1		 3b9mA-4ac0A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ays AMYLOSUCRASE

(Deinococcus
radiodurans) 		PF00128
(Alpha-amylase) 		4 LEU A 496
ARG A 470
LEU A 471
ALA A 455
 None
 0.97A 3b9mA-4aysA:
1.9		 3b9mA-4aysA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bji TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1

(Schizosaccharomyces
pombe) 		PF09734
(Tau95) 		4 LEU A 252
ARG A 232
LEU A 228
ALA A 239
 None
 1.13A 3b9mA-4bjiA:
undetectable		 3b9mA-4bjiA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bwi PHYTOCHROME-LIKE
PROTEIN CPH2

(Synechocystis
sp.) 		PF00360
(PHY)
PF01590
(GAF) 		4 LEU A 406
ARG A 207
LEU A 208
ALA A 203
 None
 1.10A 3b9mA-4bwiA:
undetectable		 3b9mA-4bwiA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d5c TETRACYCLINE
REPRESSOR PROTEIN
TETR

(Proteus
mirabilis) 		PF00440
(TetR_N)
PF02909
(TetR_C) 		4 LEU A  14
ARG A  49
LEU A  51
ALA A  56
 None
 1.04A 3b9mA-4d5cA:
2.9		 3b9mA-4d5cA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4grh AMINODEOXYCHORISMATE
SYNTHASE

(Stenotrophomonas
maltophilia) 		PF00425
(Chorismate_bind)
PF04715
(Anth_synt_I_N) 		4 LEU A  10
ARG A  26
LEU A  19
ALA A 164
 None
 1.06A 3b9mA-4grhA:
undetectable		 3b9mA-4grhA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h3t CRISPR-ASSOCIATED
PROTEIN, CSE1 FAMILY

(Acidimicrobium
ferrooxidans) 		PF09481
(CRISPR_Cse1) 		4 LEU A 495
ARG A 325
LEU A 460
ALA A 453
 None
 1.20A 3b9mA-4h3tA:
2.7		 3b9mA-4h3tA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN

(Agrobacterium
fabrum) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A  33
ARG A 343
LEU A 342
ALA A 369
 None
 1.05A 3b9mA-4hpnA:
undetectable		 3b9mA-4hpnA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kng LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 5

(Homo sapiens) 		PF00560
(LRR_1)
PF01462
(LRRNT)
PF13855
(LRR_8) 		4 LEU A 193
ARG A 183
LEU A 209
ALA A 205
 None
 1.19A 3b9mA-4kngA:
undetectable		 3b9mA-4kngA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kt3 UNCHARACTERIZED
PROTEIN

(Pseudomonas
protegens) 		PF01832
(Glucosaminidase) 		4 LEU A  57
ARG A 144
LEU A 142
ALA A 137
 None
 1.21A 3b9mA-4kt3A:
1.9		 3b9mA-4kt3A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kt7 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE

(Anaerococcus
prevotii) 		PF01128
(IspD) 		4 LEU A  93
ARG A 199
LEU A 193
ALA A 175
 None
 1.19A 3b9mA-4kt7A:
undetectable		 3b9mA-4kt7A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mrq PHOSPHOMANNOMUTASE/P
HOSPHOGLUCOMUTASE

(Pseudomonas
aeruginosa) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 LEU A 459
ARG A 394
LEU A 392
ALA A 387
 None
 1.16A 3b9mA-4mrqA:
undetectable		 3b9mA-4mrqA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mx3 CAMP-DEPENDENT
PROTEIN KINASE TYPE
I-ALPHA REGULATORY
SUBUNIT

(Bos taurus) 		PF00027
(cNMP_binding) 		4 LEU A 248
ARG A 355
LEU A 357
ALA A 268
 None
 1.10A 3b9mA-4mx3A:
undetectable		 3b9mA-4mx3A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4myd 2-SUCCINYL-6-HYDROXY
-2,4-CYCLOHEXADIENE-
1-CARBOXYLATE
SYNTHASE

(Escherichia
coli) 		PF12697
(Abhydrolase_6) 		4 LEU A  20
ARG A  69
LEU A  72
ALA A  95
 None
 1.08A 3b9mA-4mydA:
undetectable		 3b9mA-4mydA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nx1 C4-DICARBOXYLATE
TRANSPORT SYSTEM
SUBSTRATE-BINDING
PROTEIN

(Sulfitobacter
sp. NAS-14.1) 		PF03480
(DctP) 		4 LEU A 132
ARG A 328
LEU A 113
ALA A 315
 None
 0.96A 3b9mA-4nx1A:
undetectable		 3b9mA-4nx1A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ony EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 5

(Brucella
melitensis) 		PF00496
(SBP_bac_5) 		4 LEU A 414
ARG A 458
LEU A 456
ALA A 407
 None
 1.09A 3b9mA-4onyA:
undetectable		 3b9mA-4onyA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p72 PHENYLALANINE--TRNA
LIGASE BETA SUBUNIT

(Pseudomonas
aeruginosa) 		PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		4 LEU A 735
ARG A 785
LEU A 782
ALA A 726
 None
 0.91A 3b9mA-4p72A:
undetectable		 3b9mA-4p72A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qt9 PUTATIVE
GLUCOAMYLASE

(Bacteroides
caccae) 		PF10091
(Glycoamylase) 		4 LEU A 455
ARG A 207
LEU A 214
ALA A 254
 None
 1.15A 3b9mA-4qt9A:
1.3		 3b9mA-4qt9A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s05 DNA-BINDING
TRANSCRIPTIONAL
REGULATOR BASR

(Klebsiella
pneumoniae) 		PF00072
(Response_reg)
PF00486
(Trans_reg_C) 		4 LEU A 150
ARG A 133
LEU A 132
ALA A 147
 None
 1.15A 3b9mA-4s05A:
undetectable		 3b9mA-4s05A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tkt AT-LESS POLYKETIDE
SYNTHASE

(Streptomyces
platensis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		4 LEU A3634
ARG A3621
LEU A3617
ALA A3735
 None
GOL  A4006 (-3.0A)
None
GOL  A4006 (-3.6A)
 1.18A 3b9mA-4tktA:
undetectable		 3b9mA-4tktA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xai MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TAILLESS
ORTHOLOG

(Escherichia
coli;
Tribolium
castaneum) 		PF00104
(Hormone_recep)
PF13416
(SBP_bac_8) 		4 LEU A1242
ARG A1339
LEU A1340
ALA A1302
 None
 1.14A 3b9mA-4xaiA:
3.2		 3b9mA-4xaiA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y82 PROTEASOME SUBUNIT
BETA TYPE-7

(Saccharomyces
cerevisiae) 		PF00227
(Proteasome) 		4 LEU M 184
ARG M 156
LEU M 155
ALA M 148
 None
 0.97A 3b9mA-4y82M:
undetectable		 3b9mA-4y82M:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ynu GLUCOSE OXIDASE,
PUTATIVE

(Aspergillus
flavus) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 LEU A 329
ARG A 464
LEU A 468
ALA A 473
 None
 1.12A 3b9mA-4ynuA:
3.0		 3b9mA-4ynuA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zhv YFIB

(Pseudomonas
aeruginosa) 		PF00691
(OmpA) 		4 LEU A  97
ARG A  77
LEU A  80
ALA A 123
 None
 1.04A 3b9mA-4zhvA:
undetectable		 3b9mA-4zhvA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ztu DNA POLYMERASE
SUBUNIT GAMMA-2,
MITOCHONDRIAL

(Homo sapiens) 		PF03129
(HGTP_anticodon) 		4 LEU B 102
ARG B 458
LEU B 372
ALA B 379
 None
 1.08A 3b9mA-4ztuB:
undetectable		 3b9mA-4ztuB:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5by7 3-OXOACYL-ACP
SYNTHASE III

(Verrucosispora
maris) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 LEU A 293
ARG A 115
LEU A 167
ALA A 177
 None
 0.85A 3b9mA-5by7A:
undetectable		 3b9mA-5by7A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c53 POL GAMMA B

(Homo sapiens) 		PF03129
(HGTP_anticodon) 		4 LEU B 102
ARG B 458
LEU B 372
ALA B 379
 None
 1.07A 3b9mA-5c53B:
undetectable		 3b9mA-5c53B:
20.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus) 		PF00273
(Serum_albumin) 		4 LEU A 218
ARG A 256
LEU A 259
ALA A 290
 None
PG4  A 602 (-4.1A)
PG4  A 602 ( 4.5A)
PG4  A 602 (-3.4A)
 0.60A 3b9mA-5dqfA:
38.6		 3b9mA-5dqfA:
76.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ds0 PEPTIDASE M42

(Thaumarchaeota
archaeon SCGC
AB-539-E09) 		PF05343
(Peptidase_M42) 		4 LEU A 290
ARG A 349
LEU A 346
ALA A 286
 None
 1.02A 3b9mA-5ds0A:
undetectable		 3b9mA-5ds0A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eb0 YFIB

(Pseudomonas
aeruginosa) 		PF00691
(OmpA) 		4 LEU A  97
ARG A  77
LEU A  80
ALA A 123
 None
 1.09A 3b9mA-5eb0A:
undetectable		 3b9mA-5eb0A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5u BETA-HEXOSAMINIDASE

(Pseudomonas
aeruginosa) 		PF00933
(Glyco_hydro_3) 		4 LEU A  59
ARG A  19
LEU A  22
ALA A  49
 None
 1.14A 3b9mA-5g5uA:
undetectable		 3b9mA-5g5uA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5u BETA-HEXOSAMINIDASE

(Pseudomonas
aeruginosa) 		PF00933
(Glyco_hydro_3) 		4 LEU A  59
ARG A  19
LEU A  22
ALA A  52
 None
 0.99A 3b9mA-5g5uA:
undetectable		 3b9mA-5g5uA:
19.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus) 		PF00273
(Serum_albumin) 		4 LEU A 219
ARG A 257
LEU A 260
ALA A 291
 None
 0.58A 3b9mA-5ghkA:
36.7		 3b9mA-5ghkA:
79.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hiw CYTOCHROME P450
CYP260B1

(Sorangium
cellulosum) 		PF00067
(p450) 		4 LEU A 223
ARG A 146
LEU A 142
ALA A 182
 None
 0.94A 3b9mA-5hiwA:
undetectable		 3b9mA-5hiwA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Saccharomyces
cerevisiae) 		PF00562
(RNA_pol_Rpb2_6)
PF00623
(RNA_pol_Rpb1_2)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 LEU B1207
ARG A1399
LEU A1397
ALA A1412
 None
 1.13A 3b9mA-5ip9B:
2.5		 3b9mA-5ip9B:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m42 PROLINE
DEHYDROGENASE

(Thermus
thermophilus) 		PF01619
(Pro_dh) 		4 LEU A 103
ARG A 121
LEU A 120
ALA A 114
 None
 1.18A 3b9mA-5m42A:
undetectable		 3b9mA-5m42A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m42 PROLINE
DEHYDROGENASE

(Thermus
thermophilus) 		PF01619
(Pro_dh) 		4 LEU A 132
ARG A 117
LEU A 120
ALA A 149
 None
 1.14A 3b9mA-5m42A:
undetectable		 3b9mA-5m42A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mru TETRACYCLINE
REPRESSOR, CLASS A

(Pseudomonas sp.) 		no annotation 4 LEU A  14
ARG A  49
LEU A  51
ALA A  56
 None
 0.95A 3b9mA-5mruA:
4.2		 3b9mA-5mruA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mso CARBOXYLIC ACID
REDUCTASE

(Mycobacterium
marinum) 		PF07993
(NAD_binding_4) 		4 LEU A 782
ARG A 864
LEU A 862
ALA A 871
 None
 1.21A 3b9mA-5msoA:
undetectable		 3b9mA-5msoA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oc1 ARYL-ALCOHOL OXIDASE

(Pleurotus
eryngii) 		no annotation 4 LEU A 416
ARG A 365
LEU A 366
ALA A 380
 None
 1.15A 3b9mA-5oc1A:
2.1		 3b9mA-5oc1A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5odo ISOMERASE

(Rhodococcus
erythropolis) 		no annotation 4 LEU A 389
ARG A  76
LEU A 380
ALA A 192
 None
FMT  A 607 (-3.6A)
None
FMT  A 607 ( 4.4A)
 1.05A 3b9mA-5odoA:
undetectable		 3b9mA-5odoA:
20.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ori ALBUMIN

(Capra hircus) 		no annotation 4 LEU A 218
ARG A 256
LEU A 259
ALA A 290
 None
 0.80A 3b9mA-5oriA:
36.8		 3b9mA-5oriA:
74.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u0i GLUTAMINASE KIDNEY
ISOFORM,
MITOCHONDRIAL

(Homo sapiens) 		PF12796
(Ank_2) 		4 LEU A 605
ARG A 587
LEU A 558
ALA A 594
 None
 1.09A 3b9mA-5u0iA:
undetectable		 3b9mA-5u0iA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u0k GLUTAMINASE LIVER
ISOFORM,
MITOCHONDRIAL

(Homo sapiens) 		PF12796
(Ank_2) 		4 LEU A 538
ARG A 520
LEU A 491
ALA A 527
 None
 1.12A 3b9mA-5u0kA:
undetectable		 3b9mA-5u0kA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w1e PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Streptomyces
coelicolor) 		no annotation 4 LEU A 501
ARG A 411
LEU A 383
ALA A 482
 None
 1.04A 3b9mA-5w1eA:
2.0		 3b9mA-5w1eA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog DNA-DIRECTED RNA
POLYMERASE SUBUNIT
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA

(Komagataella
phaffii) 		PF00562
(RNA_pol_Rpb2_6)
PF00623
(RNA_pol_Rpb1_2)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 LEU B1207
ARG A1402
LEU A1400
ALA A1415
 None
 1.03A 3b9mA-5xogB:
undetectable		 3b9mA-5xogB:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ysm CYTOCHROME P450

(Amycolatopsis
mediterranei) 		no annotation 4 LEU A 241
ARG A 129
LEU A 121
ALA A 235
 None
 1.21A 3b9mA-5ysmA:
undetectable		 3b9mA-5ysmA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c33 5'-3' EXONUCLEASE

(Mycolicibacterium
smegmatis) 		no annotation 4 LEU A  55
ARG A 309
LEU A 310
ALA A  42
 None
 1.12A 3b9mA-6c33A:
undetectable		 3b9mA-6c33A:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6h25 -

(-) 		no annotation 4 LEU B 228
ARG B  23
LEU B  22
ALA B 137
 None
 1.11A 3b9mA-6h25B:
undetectable		 3b9mA-6h25B:
undetectable