SIMILAR PATTERNS OF AMINO ACIDS FOR 3B6R_B_CRNB603

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1crk CREATINE KINASE

(Gallus gallus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		5 THR A  66
VAL A  67
GLU A 227
CYH A 278
SER A 280
 None
 0.80A 3b6rB-1crkA:
49.8		 3b6rB-1crkA:
63.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d6h CHALCONE SYNTHASE

(Medicago sativa) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 THR A 169
VAL A 170
GLU A 192
CYH A 190
 None
 1.14A 3b6rB-1d6hA:
undetectable		 3b6rB-1d6hA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ee0 2-PYRONE SYNTHASE

(Gerbera hybrid
cultivar) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 THR A 174
VAL A 175
GLU A 197
CYH A 195
 None
 1.16A 3b6rB-1ee0A:
undetectable		 3b6rB-1ee0A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eg7 FORMYLTETRAHYDROFOLA
TE SYNTHETASE

(Moorella
thermoacetica) 		PF01268
(FTHFS) 		4 THR A1300
VAL A1299
LEU A1061
SER A1078
 None
 1.23A 3b6rB-1eg7A:
0.0		 3b6rB-1eg7A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE

(Arthrobacter
globiformis) 		PF00903
(Glyoxalase) 		4 THR A 198
VAL A 199
GLU A 267
SER A 251
 None
None
MN  A 500 (-2.8A)
None
 1.20A 3b6rB-1f1uA:
undetectable		 3b6rB-1f1uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE

(Brevibacterium
fuscum) 		PF00903
(Glyoxalase) 		4 THR A 198
VAL A 199
GLU A 267
SER A 251
 None
None
FEL  A 500 (-2.4A)
FEL  A 500 ( 4.3A)
 1.19A 3b6rB-1f1xA:
undetectable		 3b6rB-1f1xA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN

(Homo sapiens) 		PF00023
(Ank)
PF12796
(Ank_2) 		4 THR A 174
VAL A 172
CYH A 212
SER A 209
 None
 1.11A 3b6rB-1k1bA:
undetectable		 3b6rB-1k1bA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ms8 TRANS-SIALIDASE

(Trypanosoma
cruzi) 		PF13385
(Laminin_G_3)
PF13859
(BNR_3) 		4 THR A 415
VAL A 414
LEU A 419
SER A 393
 None
 1.03A 3b6rB-1ms8A:
0.0		 3b6rB-1ms8A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qdl PROTEIN
(ANTHRANILATE
SYNTHASE
(TRPE-SUBUNIT))

(Sulfolobus
solfataricus) 		PF00425
(Chorismate_bind)
PF04715
(Anth_synt_I_N) 		4 VAL A  15
LEU A  28
GLU A  30
SER A  11
 None
 1.03A 3b6rB-1qdlA:
undetectable		 3b6rB-1qdlA:
20.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qh4 CREATINE KINASE

(Gallus gallus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 THR A  71
VAL A  72
CYH A 283
SER A 285
 ACT  A1502 (-4.6A)
ACT  A1502 (-3.6A)
ACT  A1502 ( 4.1A)
ACT  A1502 ( 3.8A)
 0.28A 3b6rB-1qh4A:
53.9		 3b6rB-1qh4A:
90.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qi7 PROTEIN
(N-GLYCOSIDASE)

(Saponaria
officinalis) 		PF00161
(RIP) 		4 VAL A   9
LEU A 147
GLU A 151
SER A  58
 None
 1.19A 3b6rB-1qi7A:
undetectable		 3b6rB-1qi7A:
23.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qk1 CREATINE KINASE,
UBIQUITOUS
MITOCHONDRIAL

(Homo sapiens) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 THR A  66
VAL A  67
CYH A 278
SER A 280
 None
 0.40A 3b6rB-1qk1A:
50.0		 3b6rB-1qk1A:
66.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rih HEAVY CHAIN OF
ANTIBODY 14F7

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 THR H 110
VAL H 111
LEU H 170
SER H  84
 None
 1.25A 3b6rB-1rihH:
undetectable		 3b6rB-1rihH:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u0u DIHYDROPINOSYLVIN
SYNTHASE

(Pinus
sylvestris) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 THR A 172
VAL A 173
GLU A 195
CYH A 193
 None
 1.25A 3b6rB-1u0uA:
undetectable		 3b6rB-1u0uA:
22.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1u6r CREATINE KINASE, M
CHAIN

(Oryctolagus
cuniculus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		5 THR A  70
VAL A  71
GLU A 231
CYH A 282
SER A 284
 None
 0.82A 3b6rB-1u6rA:
53.8		 3b6rB-1u6rA:
79.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v2a GLUTATHIONE
TRANSFERASE GST1-6

(Anopheles dirus) 		PF00043
(GST_C)
PF13417
(GST_N_3) 		4 VAL A  68
LEU A  96
CYH A 156
SER A  14
 None
 1.08A 3b6rB-1v2aA:
undetectable		 3b6rB-1v2aA:
20.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1vrp CREATINE KINASE, M
CHAIN

(Tetronarce
californica) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 THR A  71
VAL A  72
CYH A 283
SER A 285
 None
 0.41A 3b6rB-1vrpA:
54.3		 3b6rB-1vrpA:
78.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x5m CALCYCLIN-BINDING
PROTEIN

(Homo sapiens) 		PF04969
(CS) 		4 THR A  54
LEU A  77
CYH A  99
SER A  86
 None
 1.13A 3b6rB-1x5mA:
undetectable		 3b6rB-1x5mA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z1e STILBENE SYNTHASE

(Arachis
hypogaea) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 THR A 169
VAL A 170
GLU A 192
CYH A 190
 None
 1.19A 3b6rB-1z1eA:
undetectable		 3b6rB-1z1eA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2avx REGULATORY PROTEIN
SDIA

(Escherichia
coli) 		PF03472
(Autoind_bind) 		4 THR A 120
VAL A 119
LEU A 133
GLU A  31
 None
 1.07A 3b6rB-2avxA:
undetectable		 3b6rB-2avxA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cu5 CONSERVED
HYPOTHETICAL PROTEIN
TT1486

(Thermus
thermophilus) 		PF01894
(UPF0047) 		4 VAL A  38
LEU A 113
GLU A 115
CYH A  43
 None
 1.13A 3b6rB-2cu5A:
undetectable		 3b6rB-2cu5A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d52 PENTAKETIDE CHROMONE
SYNTHASE

(Aloe
arborescens) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 THR A 182
VAL A 183
GLU A 205
CYH A 203
 None
 1.15A 3b6rB-2d52A:
undetectable		 3b6rB-2d52A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ej8 DCC-INTERACTING
PROTEIN 13 ALPHA

(Homo sapiens) 		PF00640
(PID) 		4 THR A  64
VAL A  63
LEU A  84
SER A 134
 None
 1.26A 3b6rB-2ej8A:
undetectable		 3b6rB-2ej8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f9r SPHINGOMYELINASE D 1

(Loxosceles
laeta) 		no annotation 4 THR A  45
VAL A  35
LEU A  67
GLU A 112
 None
 1.20A 3b6rB-2f9rA:
undetectable		 3b6rB-2f9rA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jxu TERB

(Klebsiella
pneumoniae) 		PF05099
(TerB) 		4 THR A  34
VAL A  35
LEU A  60
GLU A  65
 None
 1.27A 3b6rB-2jxuA:
undetectable		 3b6rB-2jxuA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2km6 NACHT, LRR AND PYD
DOMAINS-CONTAINING
PROTEIN 7

(Homo sapiens) 		PF02758
(PYRIN) 		4 THR A  73
VAL A  74
LEU A  15
CYH A  86
 None
 1.20A 3b6rB-2km6A:
undetectable		 3b6rB-2km6A:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nnu REGULATORY PROTEIN
E2

(Alphapapillomavirus
9) 		PF00508
(PPV_E2_N) 		4 THR A 146
VAL A 145
GLU A  90
SER A  85
 None
 1.18A 3b6rB-2nnuA:
undetectable		 3b6rB-2nnuA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p0u STILBENECARBOXYLATE
SYNTHASE 2

(Marchantia
polymorpha) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 THR A 187
VAL A 188
GLU A 210
CYH A 208
 None
 1.14A 3b6rB-2p0uA:
undetectable		 3b6rB-2p0uA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q3z TRANSGLUTAMINASE 2

(Homo sapiens) 		PF00868
(Transglut_N)
PF00927
(Transglut_C)
PF01841
(Transglut_core) 		4 THR A 286
VAL A 287
LEU A 261
CYH A 193
 None
 1.17A 3b6rB-2q3zA:
undetectable		 3b6rB-2q3zA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q8q IRON-REGULATED
SURFACE DETERMINANT
E

(Staphylococcus
aureus) 		PF01497
(Peripla_BP_2) 		4 THR A  40
VAL A  41
GLU A 265
SER A  60
 HEM  A 300 (-4.0A)
HEM  A 300 (-3.5A)
None
HEM  A 300 (-2.7A)
 1.15A 3b6rB-2q8qA:
undetectable		 3b6rB-2q8qA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xua 3-OXOADIPATE
ENOL-LACTONASE

(Paraburkholderia
xenovorans) 		PF12146
(Hydrolase_4) 		4 THR A 255
VAL A 258
LEU A  49
CYH A  97
 None
 1.06A 3b6rB-2xuaA:
undetectable		 3b6rB-2xuaA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yuy RHO GTPASE
ACTIVATING PROTEIN
21

(Homo sapiens) 		PF00595
(PDZ) 		4 THR A  13
VAL A  12
LEU A 112
SER A 115
 None
 1.11A 3b6rB-2yuyA:
undetectable		 3b6rB-2yuyA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5r BENZALACETONE
SYNTHASE

(Rheum palmatum) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 THR A 162
VAL A 163
GLU A 185
CYH A 183
 None
 1.15A 3b6rB-3a5rA:
undetectable		 3b6rB-3a5rA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3awk CHALCONE
SYNTHASE-LIKE
POLYKETIDE SYNTHASE

(Huperzia
serrata) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 THR A 179
VAL A 180
GLU A 202
CYH A 200
 None
 1.12A 3b6rB-3awkA:
undetectable		 3b6rB-3awkA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b46 AMINOTRANSFERASE
BNA3

(Saccharomyces
cerevisiae) 		PF00155
(Aminotran_1_2) 		4 THR A 119
VAL A 120
GLU A 126
SER A 305
 None
 1.17A 3b6rB-3b46A:
undetectable		 3b6rB-3b46A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bsx PUMILIO HOMOLOG 1

(Homo sapiens) 		PF00806
(PUF) 		4 VAL A1082
LEU A1097
GLU A1100
SER A1073
 None
 1.21A 3b6rB-3bsxA:
undetectable		 3b6rB-3bsxA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bt4 FUNGAL PROTEASE
INHIBITOR-1

(Antheraea
mylitta) 		PF12190
(amfpi-1) 		4 THR A  28
VAL A  44
LEU A  46
GLU A  70
 None
 1.26A 3b6rB-3bt4A:
undetectable		 3b6rB-3bt4A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dao PUTATIVE PHOSPHATE

([Eubacterium]
rectale) 		PF08282
(Hydrolase_3) 		4 THR A 151
VAL A 152
GLU A 159
CYH A 162
 1PE  A 265 ( 4.1A)
None
None
None
 0.98A 3b6rB-3daoA:
undetectable		 3b6rB-3daoA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3doj DEHYDROGENASE-LIKE
PROTEIN

(Arabidopsis
thaliana) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 THR A  95
VAL A  96
LEU A 171
SER A 101
 None
 1.04A 3b6rB-3dojA:
undetectable		 3b6rB-3dojA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dr2 EXPORTED
GLUCONOLACTONASE

(Xanthomonas
campestris) 		PF08450
(SGL) 		4 VAL A 236
LEU A 269
CYH A 261
SER A 256
 None
 1.16A 3b6rB-3dr2A:
undetectable		 3b6rB-3dr2A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eck PROTEIN
(HOMOPROTOCATECHUATE
2,3-DIOXYGENASE)

(Brevibacterium
fuscum) 		PF00903
(Glyoxalase) 		4 THR A 198
VAL A 199
GLU A 267
SER A 251
 None
None
FE2  A 500 (-2.7A)
None
 1.14A 3b6rB-3eckA:
undetectable		 3b6rB-3eckA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hd6 AMMONIUM TRANSPORTER
RH TYPE C

(Homo sapiens) 		PF00909
(Ammonium_transp) 		4 THR A 160
VAL A 159
GLU A 166
CYH A 131
 None
 1.22A 3b6rB-3hd6A:
undetectable		 3b6rB-3hd6A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hdg UNCHARACTERIZED
PROTEIN

(Wolinella
succinogenes) 		PF00072
(Response_reg) 		4 THR A  58
VAL A  85
LEU A  68
SER A  87
 None
 1.08A 3b6rB-3hdgA:
undetectable		 3b6rB-3hdgA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hdv RESPONSE REGULATOR

(Pseudomonas
putida) 		PF00072
(Response_reg) 		4 THR A 119
VAL A 147
GLU A 156
SER A 149
 None
 1.24A 3b6rB-3hdvA:
undetectable		 3b6rB-3hdvA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hx6 TYPE 4 FIMBRIAL
BIOGENESIS PROTEIN
PILY1

(Pseudomonas
aeruginosa) 		PF05567
(Neisseria_PilC) 		4 THR A1087
VAL A1088
LEU A1091
SER A1113
 None
 1.26A 3b6rB-3hx6A:
undetectable		 3b6rB-3hx6A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k12 UNCHARACTERIZED
PROTEIN A6V7T0

(Pseudomonas
aeruginosa) 		PF01042
(Ribonuc_L-PSP) 		4 THR A  23
VAL A  24
LEU A  64
SER A  58
 None
 1.26A 3b6rB-3k12A:
undetectable		 3b6rB-3k12A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kyj PUTATIVE HISTIDINE
PROTEIN KINASE

(Rhodobacter
sphaeroides) 		PF01627
(Hpt) 		4 VAL A  84
LEU A  75
CYH A 134
SER A 135
 None
 1.16A 3b6rB-3kyjA:
undetectable		 3b6rB-3kyjA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lgx D-ALANINE--POLY(PHOS
PHORIBITOL) LIGASE
SUBUNIT 1

(Streptococcus
pyogenes) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 THR A  70
VAL A  67
GLU A   6
SER A  34
 None
 1.12A 3b6rB-3lgxA:
undetectable		 3b6rB-3lgxA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mvd REGULATOR OF
CHROMOSOME
CONDENSATION

(Drosophila
melanogaster) 		PF00415
(RCC1) 		4 THR K 305
VAL K 306
CYH K 352
SER K 357
 None
 1.16A 3b6rB-3mvdK:
undetectable		 3b6rB-3mvdK:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o4z TELOMERE LENGTH
REGULATION PROTEIN
TEL2

(Saccharomyces
cerevisiae) 		PF10193
(Telomere_reg-2) 		4 THR A 230
VAL A 229
LEU A 234
SER A 260
 None
 1.20A 3b6rB-3o4zA:
undetectable		 3b6rB-3o4zA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ocr CLASS II
ALDOLASE/ADDUCIN
DOMAIN PROTEIN

(Pseudomonas
savastanoi) 		PF00596
(Aldolase_II) 		4 VAL A 134
LEU A 190
GLU A 208
CYH A 211
 None
 1.11A 3b6rB-3ocrA:
2.1		 3b6rB-3ocrA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3om5 LEVANSUCRASE

(Bacillus
megaterium) 		PF02435
(Glyco_hydro_68) 		4 THR A 375
VAL A 347
LEU A 307
GLU A 303
 None
 1.18A 3b6rB-3om5A:
undetectable		 3b6rB-3om5A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pdu 3-HYDROXYISOBUTYRATE
DEHYDROGENASE FAMILY
PROTEIN

(Geobacter
sulfurreducens) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 THR A  96
VAL A  97
LEU A 172
SER A 102
 NAP  A 301 (-4.1A)
None
None
None
 1.00A 3b6rB-3pduA:
undetectable		 3b6rB-3pduA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pef 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
NAD-BINDING

(Geobacter
metallireducens) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 THR A  96
VAL A  97
LEU A 172
SER A 102
 NAP  A 301 (-4.1A)
None
None
None
 0.93A 3b6rB-3pefA:
undetectable		 3b6rB-3pefA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q8x ANTIDOTE OF
EPSILON-ZETA
POSTSEGREGATIONAL
KILLING SYSTEM
ZETA-TOXIN

(Streptococcus
pyogenes) 		PF06414
(Zeta_toxin)
PF08998
(Epsilon_antitox) 		4 THR A   4
VAL A   3
GLU A  12
SER B  48
 None
None
SO4  B 602 (-3.2A)
None
 1.17A 3b6rB-3q8xA:
undetectable		 3b6rB-3q8xA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sgi DNA LIGASE

(Mycobacterium
tuberculosis) 		PF01653
(DNA_ligase_aden)
PF03120
(DNA_ligase_OB) 		4 THR A 149
VAL A  83
GLU A 180
SER A 142
 None
 1.05A 3b6rB-3sgiA:
undetectable		 3b6rB-3sgiA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsy FUSION PROTEIN
4-COUMARATE--COA
LIGASE 1,
RESVERATROL SYNTHASE

(Arabidopsis
thaliana;
Vitis vinifera) 		PF00195
(Chal_sti_synt_N)
PF00501
(AMP-binding)
PF02797
(Chal_sti_synt_C)
PF13193
(AMP-binding_C) 		4 THR A 756
VAL A 757
GLU A 779
CYH A 777
 None
 1.19A 3b6rB-3tsyA:
undetectable		 3b6rB-3tsyA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE

(Sinorhizobium
meliloti) 		PF08013
(Tagatose_6_P_K) 		4 THR A 132
LEU A 143
GLU A 139
CYH A 136
 None
 1.08A 3b6rB-3txvA:
undetectable		 3b6rB-3txvA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ui2 SIGNAL RECOGNITION
PARTICLE 43 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF12796
(Ank_2) 		4 VAL A 167
LEU A 144
CYH A 175
SER A 172
 None
 1.27A 3b6rB-3ui2A:
undetectable		 3b6rB-3ui2A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ujq LEGUME LECTIN

(Lablab
purpureus) 		PF00139
(Lectin_legB) 		4 THR A  86
VAL A  87
LEU A 256
SER A 193
 None
 1.23A 3b6rB-3ujqA:
undetectable		 3b6rB-3ujqA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vk9 GLUTATHIONE
S-TRANSFERASE DELTA

(Bombyx mori) 		PF13417
(GST_N_3)
PF14497
(GST_C_3) 		4 THR A  53
VAL A  54
CYH A  14
SER A  11
 None
 1.20A 3b6rB-3vk9A:
undetectable		 3b6rB-3vk9A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4am3 POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE

(Caulobacter
vibrioides) 		PF00013
(KH_1)
PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF03726
(PNPase) 		4 THR A 325
VAL A 326
GLU A 530
SER A 481
 None
 1.22A 3b6rB-4am3A:
1.6		 3b6rB-4am3A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bej DYNAMIN 1-LIKE
PROTEIN

(Homo sapiens) 		PF00350
(Dynamin_N)
PF01031
(Dynamin_M)
PF02212
(GED) 		4 THR A 259
VAL A 258
GLU A 265
SER A  44
 None
 1.09A 3b6rB-4bejA:
undetectable		 3b6rB-4bejA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cmr GLYCOSYL
HYDROLASE/DEACETYLAS
E FAMILY PROTEIN

(Pyrococcus sp.
ST04) 		no annotation 4 THR A 111
VAL A 112
LEU A 151
SER A 130
 None
 1.25A 3b6rB-4cmrA:
undetectable		 3b6rB-4cmrA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i62 AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING
PROTEIN, PUTATIVE

(Streptococcus
pneumoniae) 		PF00497
(SBP_bac_3) 		4 THR A 244
VAL A 241
LEU A  70
SER A 121
 None
 1.10A 3b6rB-4i62A:
undetectable		 3b6rB-4i62A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lhu 9C2 TCR GAMMA CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 VAL G 201
LEU G 179
GLU G 172
SER G 205
 None
 0.97A 3b6rB-4lhuG:
undetectable		 3b6rB-4lhuG:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4li2 LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 4

(Xenopus
tropicalis) 		PF13516
(LRR_6)
PF13855
(LRR_8) 		4 THR A 122
VAL A 123
GLU A 126
SER A 151
 None
 1.20A 3b6rB-4li2A:
undetectable		 3b6rB-4li2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0n REPLICASE
POLYPROTEIN 1AB

(Equine
arteritis virus) 		PF01443
(Viral_helicase1) 		4 VAL A 183
LEU A 168
CYH A 192
SER A 188
 None
 1.18A 3b6rB-4n0nA:
undetectable		 3b6rB-4n0nA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n78 ABL INTERACTOR 2
WISKOTT-ALDRICH
SYNDROME PROTEIN
FAMILY MEMBER 1

(Homo sapiens) 		PF02205
(WH2)
PF07815
(Abi_HHR) 		4 THR F  96
VAL F  97
LEU D  83
GLU D  88
 None
 1.23A 3b6rB-4n78F:
undetectable		 3b6rB-4n78F:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nv1 FORMYLTRANSFERASE

(Francisella
tularensis) 		no annotation 4 THR C   8
LEU C  14
GLU C  44
SER C  37
 None
 1.25A 3b6rB-4nv1C:
undetectable		 3b6rB-4nv1C:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oko RAPID ENCYSTMENT
PHENOTYPE PROTEIN 34
KDA

(Francisella
tularensis) 		PF00246
(Peptidase_M14) 		4 THR A 270
LEU A 258
GLU A 256
CYH A 251
 ACT  A 402 ( 3.9A)
ACT  A 402 ( 4.7A)
None
None
 1.20A 3b6rB-4okoA:
undetectable		 3b6rB-4okoA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oko RAPID ENCYSTMENT
PHENOTYPE PROTEIN 34
KDA

(Francisella
tularensis) 		PF00246
(Peptidase_M14) 		4 VAL A 205
LEU A 258
GLU A 256
CYH A 251
 None
ACT  A 402 ( 4.7A)
None
None
 1.11A 3b6rB-4okoA:
undetectable		 3b6rB-4okoA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rf7 ARGININE KINASE

(Anthopleura
japonica) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 VAL A  69
GLU A 229
CYH A 275
SER A 277
 ARG  A 805 (-3.6A)
ARG  A 805 (-2.9A)
ARG  A 805 (-3.4A)
ARG  A 805 ( 3.7A)
 0.46A 3b6rB-4rf7A:
29.7		 3b6rB-4rf7A:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tlg SEC14-LIKE PROTEIN 4

(Homo sapiens) 		PF00650
(CRAL_TRIO) 		4 THR A 354
VAL A 302
LEU A 197
SER A 352
 None
None
None
EDO  A 503 (-2.7A)
 1.07A 3b6rB-4tlgA:
undetectable		 3b6rB-4tlgA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uer EIF3B

(Lachancea
kluyveri) 		PF00318
(Ribosomal_S2) 		4 THR b 638
VAL b 594
GLU b 661
SER b 601
 None
 1.25A 3b6rB-4uerb:
undetectable		 3b6rB-4uerb:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wum CHALCONE SYNTHASE

(Freesia hybrid
cultivar) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 THR A 169
VAL A 170
GLU A 192
CYH A 190
 None
 1.19A 3b6rB-4wumA:
undetectable		 3b6rB-4wumA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yhb IRON-CHELATOR
UTILIZATION PROTEIN

(Thermobifida
fusca) 		PF04954
(SIP)
PF08021
(FAD_binding_9) 		4 THR A  90
VAL A  91
GLU A 161
SER A  47
 FAD  A 301 (-3.9A)
None
None
None
 0.92A 3b6rB-4yhbA:
undetectable		 3b6rB-4yhbA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yjy CHALCONE SYNTHASE 1

(Oryza sativa) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 THR A 172
VAL A 173
GLU A 195
CYH A 193
 None
 1.13A 3b6rB-4yjyA:
undetectable		 3b6rB-4yjyA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yxy DTOR_9X31L

(synthetic
construct) 		no annotation 4 THR A  79
VAL A  80
GLU A  51
SER A  45
 None
 1.12A 3b6rB-4yxyA:
undetectable		 3b6rB-4yxyA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yxz DTOR_9X31L

(synthetic
construct) 		no annotation 4 THR A 150
VAL A 151
GLU A 122
SER A 116
 None
 1.11A 3b6rB-4yxzA:
undetectable		 3b6rB-4yxzA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z26 PUTATIVE GMC-TYPE
OXIDOREDUCTASE R135

(Acanthamoeba
polyphaga
mimivirus) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 VAL A 603
LEU A 307
CYH A 583
SER A 607
 None
 1.19A 3b6rB-4z26A:
undetectable		 3b6rB-4z26A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5esp I-PANMI

(Podospora
anserina) 		PF00961
(LAGLIDADG_1) 		4 THR A 237
VAL A 236
CYH A 221
SER A 241
 None
 1.25A 3b6rB-5espA:
undetectable		 3b6rB-5espA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fp1 TONB-DEPENDENT
SIDEROPHORE RECEPTOR

(Acinetobacter
baumannii) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 THR A 117
VAL A 116
GLU A 568
SER A  42
 None
 1.22A 3b6rB-5fp1A:
undetectable		 3b6rB-5fp1A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)

(Bacteroides
thetaiotaomicron) 		PF16403
(DUF5011)
PF16404
(DUF5012) 		4 THR G  84
VAL G  85
LEU G  67
GLU G  35
 None
 1.13A 3b6rB-5fq8G:
undetectable		 3b6rB-5fq8G:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ft3 GLUTATHIONE
S-TRANSFERASE
EPSILON 2

(Aedes aegypti) 		PF00043
(GST_C)
PF13417
(GST_N_3) 		4 THR A  54
VAL A  55
CYH A  15
SER A  12
 GSH  A1221 (-3.1A)
GSH  A1221 (-4.1A)
None
GSH  A1221 (-2.5A)
 1.20A 3b6rB-5ft3A:
undetectable		 3b6rB-5ft3A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gl6 RIBOSOME MATURATION
FACTOR RIMP

(Mycolicibacterium
smegmatis) 		PF02576
(DUF150)
PF17384
(DUF150_C) 		4 THR A  89
VAL A  88
LEU A  58
SER A  67
 None
 1.26A 3b6rB-5gl6A:
undetectable		 3b6rB-5gl6A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i68 ALCOHOL OXIDASE 1

(Komagataella
pastoris) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 VAL A 603
LEU A 277
CYH A 572
SER A 607
 None
 0.98A 3b6rB-5i68A:
undetectable		 3b6rB-5i68A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jp0 BETA-GLUCOSIDASE
BOGH3B

(Bacteroides
ovatus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 THR A 683
VAL A 684
LEU A 734
CYH A 761
 None
 1.16A 3b6rB-5jp0A:
undetectable		 3b6rB-5jp0A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ncc FATTY ACID
PHOTODECARBOXYLASE

(Chlorella
variabilis) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 VAL A 607
LEU A 350
CYH A 581
SER A 611
 None
 1.15A 3b6rB-5nccA:
undetectable		 3b6rB-5nccA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5odo ISOMERASE

(Rhodococcus
erythropolis) 		no annotation 4 THR A 359
VAL A 464
LEU A 364
SER A 467
 None
 1.25A 3b6rB-5odoA:
undetectable		 3b6rB-5odoA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tf4 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]

(Bartonella
henselae) 		PF13561
(adh_short_C2) 		4 VAL A  78
LEU A 130
CYH A  67
SER A  74
 None
 1.26A 3b6rB-5tf4A:
undetectable		 3b6rB-5tf4A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tfm CADHERIN-23

(Homo sapiens) 		no annotation 4 THR A 806
VAL A 791
GLU A 786
CYH A 840
 None
 1.11A 3b6rB-5tfmA:
undetectable		 3b6rB-5tfmA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5til ALPHA CHAIN OF
MURINE P14 T CELL
RECEPTOR

(Mus musculus) 		no annotation 4 THR K  26
VAL K  27
LEU K  18
GLU K   4
 None
 1.07A 3b6rB-5tilK:
undetectable		 3b6rB-5tilK:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uc5 CHS2 CHALCONE
SYNTHASE

(Malus domestica) 		no annotation 4 THR A 169
VAL A 170
GLU A 192
CYH A 190
 None
 1.23A 3b6rB-5uc5A:
undetectable		 3b6rB-5uc5A:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yt6 TAX1-BINDING PROTEIN
1

(Homo sapiens) 		no annotation 4 THR F  59
VAL F  57
GLU F  42
CYH F  37
 None
None
None
ZN  F 101 (-2.3A)
 1.21A 3b6rB-5yt6F:
undetectable		 3b6rB-5yt6F:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6co0 STYRYLPYRONE
SYNTHASE 1

(Piper
methysticum) 		no annotation 4 THR A 169
VAL A 170
GLU A 192
CYH A 190
 None
 1.09A 3b6rB-6co0A:
undetectable		 3b6rB-6co0A:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cqb CHALCONE SYNTHASE

(Piper
methysticum) 		no annotation 4 THR A 170
VAL A 171
GLU A 193
CYH A 191
 None
 1.26A 3b6rB-6cqbA:
undetectable		 3b6rB-6cqbA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6etz BETA-GALACTOSIDASE

(Arthrobacter
sp. 32cB) 		no annotation 4 THR A 934
VAL A1008
LEU A 930
GLU A 872
 None
 1.20A 3b6rB-6etzA:
undetectable		 3b6rB-6etzA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fg9 -

(-) 		no annotation 4 THR A 290
VAL A 289
GLU A 251
SER A 270
 None
 1.12A 3b6rB-6fg9A:
undetectable		 3b6rB-6fg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gnf -

(-) 		no annotation 4 VAL A 363
LEU A 396
GLU A 321
CYH A 322
 None
 1.19A 3b6rB-6gnfA:
undetectable		 3b6rB-6gnfA:
undetectable