SIMILAR PATTERNS OF AMINO ACIDS FOR 3B6H_A_MXDA551_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aq0 1,3-1,4-BETA-GLUCANA
SE

(Hordeum vulgare) 		PF00332
(Glyco_hydro_17) 		4 ALA A 187
LEU A 188
ALA A 242
THR A 241
 None
 0.81A 3b6hA-1aq0A:
0.0		 3b6hA-1aq0A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6v METHYL-COENZYME M
REDUCTASE I BETA
SUBUNIT

(Methanopyrus
kandleri) 		PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		4 TYR B 242
ALA B 243
LEU B 247
ALA B 437
 None
 0.64A 3b6hA-1e6vB:
undetectable		 3b6hA-1e6vB:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gqr ACETYLCHOLINESTERASE

(Tetronarce
californica) 		PF00135
(COesterase) 		4 ALA A 136
LEU A 135
ALA A 474
THR A 475
 None
 0.81A 3b6hA-1gqrA:
0.0		 3b6hA-1gqrA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hsj FUSION PROTEIN
CONSISTING OF
STAPHYLOCOCCUS
ACCESSORY REGULATOR
PROTEIN R AND
MALTOSE BINDING
PROTEIN

(Escherichia
coli;
Staphylococcus
aureus) 		PF01547
(SBP_bac_1) 		4 ALA A 188
LEU A 192
ALA A 346
THR A 345
 None
 0.88A 3b6hA-1hsjA:
undetectable		 3b6hA-1hsjA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hzf COMPLEMENT FACTOR
C4A

(Homo sapiens) 		PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 TYR A1248
ALA A1175
ALA A1124
THR A1123
 None
 0.92A 3b6hA-1hzfA:
0.0		 3b6hA-1hzfA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i4w MITOCHONDRIAL
REPLICATION PROTEIN
MTF1

(Saccharomyces
cerevisiae) 		PF00398
(RrnaAD) 		4 ALA A 206
LEU A 204
ALA A 177
THR A 176
 None
 0.89A 3b6hA-1i4wA:
0.0		 3b6hA-1i4wA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iwp GLYCEROL DEHYDRATASE
ALPHA SUBUNIT

(Klebsiella
pneumoniae) 		PF02286
(Dehydratase_LU) 		4 TYR A 250
ALA A 249
LEU A 246
ALA A 207
 None
 0.92A 3b6hA-1iwpA:
0.0		 3b6hA-1iwpA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE

(Nicotiana
tabacum) 		PF00141
(peroxidase) 		4 TYR A 251
ALA A 252
ALA A  98
THR A  99
 None
 0.87A 3b6hA-1iynA:
0.8		 3b6hA-1iynA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k50 PROTEIN L

(Finegoldia
magna) 		PF02246
(B1) 		4 TYR A  36
ALA A  37
LEU A  40
THR A  17
 None
 0.90A 3b6hA-1k50A:
undetectable		 3b6hA-1k50A:
7.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k72 ENDOGLUCANASE 9G

([Clostridium]
cellulolyticum) 		PF00759
(Glyco_hydro_9)
PF00942
(CBM_3) 		5 ALA A 224
LEU A 221
ALA A 157
THR A 156
ASN A 108
 None
 1.41A 3b6hA-1k72A:
undetectable		 3b6hA-1k72A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kh0 PROTEIN L

(Finegoldia
magna) 		PF02246
(B1) 		4 TYR A  36
ALA A  37
LEU A  40
THR A  17
 None
 0.72A 3b6hA-1kh0A:
undetectable		 3b6hA-1kh0A:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)

(Primate
T-lymphotropic
virus 1) 		PF00429
(TLV_coat)
PF13416
(SBP_bac_8) 		4 ALA A 189
LEU A 193
ALA A 347
THR A 346
 None
 0.88A 3b6hA-1mg1A:
undetectable		 3b6hA-1mg1A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ov9 VICH PROTEIN

(Vibrio cholerae) 		no annotation 4 TYR A  16
ALA A  17
LEU A  20
ALA A  28
 None
 0.86A 3b6hA-1ov9A:
undetectable		 3b6hA-1ov9A:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ovy 50S RIBOSOMAL
PROTEIN L18

(Geobacillus
stearothermophilus) 		PF00861
(Ribosomal_L18p) 		4 ALA A 110
ALA A  74
THR A  68
ASN A  70
 None
 0.80A 3b6hA-1ovyA:
undetectable		 3b6hA-1ovyA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ps6 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE

(Escherichia
coli) 		PF04166
(PdxA) 		4 TYR A  96
ALA A  79
LEU A  80
THR A  44
 None
 0.88A 3b6hA-1ps6A:
undetectable		 3b6hA-1ps6A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qwr MANNOSE-6-PHOSPHATE
ISOMERASE

(Bacillus
subtilis) 		PF01238
(PMI_typeI) 		4 ALA A 179
LEU A 180
ALA A  21
THR A  20
 None
FMT  A 606 ( 4.4A)
FMT  A 606 ( 4.6A)
None
 0.85A 3b6hA-1qwrA:
undetectable		 3b6hA-1qwrA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rtr GERANYLTRANSTRANSFER
ASE

(Staphylococcus
aureus) 		PF00348
(polyprenyl_synt) 		4 ALA A 119
LEU A 122
ALA A  20
ASN A  22
 None
 0.85A 3b6hA-1rtrA:
1.5		 3b6hA-1rtrA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL

(Escherichia
coli) 		PF00155
(Aminotran_1_2) 		4 TYR A  86
ALA A 220
LEU A 219
ALA A 228
 None
 0.88A 3b6hA-1u08A:
undetectable		 3b6hA-1u08A:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wpn MANGANESE-DEPENDENT
INORGANIC
PYROPHOSPHATASE

(Bacillus
subtilis) 		PF01368
(DHH) 		4 ALA A 166
LEU A 169
ALA A 120
THR A 119
 None
 0.87A 3b6hA-1wpnA:
undetectable		 3b6hA-1wpnA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a1a INTERFERON-INDUCED,
DOUBLE-STRANDED
RNA-ACTIVATED
PROTEIN KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR B 472
ALA B 473
LEU B 476
THR B 451
 None
 0.83A 3b6hA-2a1aB:
undetectable		 3b6hA-2a1aB:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b81 LUCIFERASE-LIKE
MONOOXYGENASE

(Bacillus cereus) 		PF00296
(Bac_luciferase) 		4 TYR A 166
LEU A 165
ALA A 117
THR A 118
 None
 0.86A 3b6hA-2b81A:
undetectable		 3b6hA-2b81A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2clp AFLATOXIN B1
ALDEHYDE REDUCTASE
MEMBER 3

(Homo sapiens) 		PF00248
(Aldo_ket_red) 		4 TYR A 285
ALA A 289
ALA A 295
THR A 296
 None
 0.84A 3b6hA-2clpA:
undetectable		 3b6hA-2clpA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fkn UROCANATE HYDRATASE

(Bacillus
subtilis) 		PF01175
(Urocanase)
PF17391
(Urocanase_N)
PF17392
(Urocanase_C) 		4 TYR A 275
ALA A 280
LEU A 283
ALA A 295
 None
 0.92A 3b6hA-2fknA:
undetectable		 3b6hA-2fknA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2haw MANGANESE-DEPENDENT
INORGANIC
PYROPHOSPHATASE

(Bacillus
subtilis) 		PF01368
(DHH)
PF02833
(DHHA2) 		4 ALA A 166
LEU A 169
ALA A 120
THR A 119
 None
 0.89A 3b6hA-2hawA:
undetectable		 3b6hA-2hawA:
22.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2iag PROSTACYCLIN
SYNTHASE

(Homo sapiens) 		PF00067
(p450) 		4 ALA A 100
ALA A 283
THR A 284
ASN A 287
 None
HEM  A 600 (-4.4A)
HEM  A 600 (-3.9A)
HEM  A 600 (-4.2A)
 0.64A 3b6hA-2iagA:
59.8		 3b6hA-2iagA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ja2 GLUTAMYL-TRNA
SYNTHETASE

(Mycobacterium
tuberculosis) 		PF00749
(tRNA-synt_1c) 		4 ALA A  64
LEU A  65
ALA A  27
THR A  26
 None
 0.88A 3b6hA-2ja2A:
undetectable		 3b6hA-2ja2A:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jbm NICOTINATE-NUCLEOTID
E PYROPHOSPHORYLASE

(Homo sapiens) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		4 ALA A 249
LEU A 223
ALA A 235
THR A 236
 None
 0.87A 3b6hA-2jbmA:
undetectable		 3b6hA-2jbmA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kac PROTEIN L

(Finegoldia
magna) 		PF02246
(B1) 		4 TYR A  36
ALA A  37
LEU A  40
THR A  17
 None
 0.92A 3b6hA-2kacA:
undetectable		 3b6hA-2kacA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nlz CEPHALOSPORIN
ACYLASE

(Bacillus
halodurans) 		PF01019
(G_glu_transpept) 		4 ALA A  74
ALA A  55
THR A  56
ASN A  66
 None
 0.87A 3b6hA-2nlzA:
undetectable		 3b6hA-2nlzA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nyx PROBABLE
TRANSCRIPTIONAL
REGULATORY PROTEIN,
RV1404

(Mycobacterium
tuberculosis) 		PF01047
(MarR) 		4 ALA A 142
LEU A 143
ALA A  24
THR A  23
 None
 0.87A 3b6hA-2nyxA:
undetectable		 3b6hA-2nyxA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wzv NFNB PROTEIN

(Mycolicibacterium
smegmatis) 		PF00881
(Nitroreductase) 		4 TYR A 162
ALA A 163
LEU A 166
ALA A 143
 None
 0.67A 3b6hA-2wzvA:
undetectable		 3b6hA-2wzvA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ab7 PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0350

(Thermus
thermophilus) 		PF00582
(Usp) 		4 ALA A 147
LEU A 146
ALA A 133
THR A 132
 ALA  A 147 ( 0.0A)
LEU  A 146 ( 0.6A)
ALA  A 133 ( 0.0A)
THR  A 132 ( 0.8A)
 0.90A 3b6hA-3ab7A:
undetectable		 3b6hA-3ab7A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjq PHAGE-RELATED
PROTEIN

(Bordetella
bronchiseptica) 		PF03864
(Phage_cap_E) 		4 ALA A 119
LEU A 120
ALA A 226
THR A 225
 PG4  A 316 ( 4.0A)
None
None
None
 0.84A 3b6hA-3bjqA:
undetectable		 3b6hA-3bjqA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dm0 MALTOSE-BINDING
PERIPLASMIC PROTEIN
FUSED WITH RACK1

(Arabidopsis
thaliana;
Escherichia
coli) 		PF00400
(WD40)
PF01547
(SBP_bac_1) 		4 ALA A 188
LEU A 192
ALA A 346
THR A 345
 None
 0.91A 3b6hA-3dm0A:
undetectable		 3b6hA-3dm0A:
23.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g7g UPF0311 PROTEIN
CA_C3321

(Clostridium
acetobutylicum) 		PF11578
(DUF3237) 		4 TYR A  88
ALA A  78
ALA A  75
ASN A  92
 None
 0.87A 3b6hA-3g7gA:
undetectable		 3b6hA-3g7gA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gve YFKN PROTEIN

(Bacillus
subtilis) 		PF00149
(Metallophos) 		4 ALA A 233
LEU A 232
ALA A 210
ASN A  59
 None
 0.79A 3b6hA-3gveA:
undetectable		 3b6hA-3gveA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hdl ROYAL PALM TREE
PEROXIDASE

(Roystonea regia) 		PF00141
(peroxidase) 		4 TYR A 200
ALA A 201
LEU A 204
THR A 246
 None
 0.92A 3b6hA-3hdlA:
undetectable		 3b6hA-3hdlA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jst PUTATIVE
PTERIN-4-ALPHA-CARBI
NOLAMINE DEHYDRATASE

(Brucella
melitensis) 		PF01329
(Pterin_4a) 		4 TYR A  52
ALA A  53
LEU A  56
THR A  82
 None
 0.81A 3b6hA-3jstA:
undetectable		 3b6hA-3jstA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k7x LIN0763 PROTEIN

(Listeria
innocua) 		PF03663
(Glyco_hydro_76) 		4 ALA A  58
LEU A  60
ALA A 107
THR A 108
 None
 0.89A 3b6hA-3k7xA:
undetectable		 3b6hA-3k7xA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n8u IMELYSIN PEPTIDASE

(Bacteroides
ovatus) 		PF09375
(Peptidase_M75) 		4 ALA A  55
LEU A  58
ALA A 301
THR A 300
 None
 0.82A 3b6hA-3n8uA:
1.4		 3b6hA-3n8uA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nv9 MALIC ENZYME

(Entamoeba
histolytica) 		PF00390
(malic)
PF03949
(Malic_M) 		4 ALA A 204
LEU A 207
ALA A 241
THR A 240
 None
 0.87A 3b6hA-3nv9A:
undetectable		 3b6hA-3nv9A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o3u MALTOSE-BINDING
PERIPLASMIC PROTEIN,
ADVANCED
GLYCOSYLATION END
PRODUCT-SPECIFIC
RECEPTOR

(Escherichia
coli;
Homo sapiens) 		PF08205
(C2-set_2)
PF13416
(SBP_bac_8) 		4 ALA N 188
LEU N 192
ALA N 346
THR N 345
 None
 0.92A 3b6hA-3o3uN:
undetectable		 3b6hA-3o3uN:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3phg SHIKIMATE
DEHYDROGENASE

(Helicobacter
pylori) 		PF08501
(Shikimate_dh_N) 		4 ALA A 134
LEU A 133
ALA A 179
THR A 180
 None
 0.72A 3b6hA-3phgA:
undetectable		 3b6hA-3phgA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3py7 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,PAXILLIN
LD1,PROTEIN E6
CHIMERA

(Deltapapillomavirus
4;
Escherichia
coli;
Homo sapiens) 		PF00518
(E6)
PF01547
(SBP_bac_1) 		4 ALA A 189
LEU A 193
ALA A 347
THR A 346
 None
 0.92A 3b6hA-3py7A:
undetectable		 3b6hA-3py7A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qlb ENANTIO-PYOCHELIN
RECEPTOR

(Pseudomonas
fluorescens) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 TYR A 415
ALA A 416
LEU A 358
ALA A 344
 None
 0.88A 3b6hA-3qlbA:
undetectable		 3b6hA-3qlbA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qp9 TYPE I POLYKETIDE
SYNTHASE PIKAII

(Streptomyces
venezuelae) 		PF08659
(KR) 		4 TYR A 394
ALA A 395
ALA A 419
THR A 466
 None
 0.91A 3b6hA-3qp9A:
undetectable		 3b6hA-3qp9A:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE

(Corynebacterium
glutamicum) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 ALA A  42
LEU A  43
ALA A 116
THR A 117
 None
 0.88A 3b6hA-3tx8A:
undetectable		 3b6hA-3tx8A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uor ABC TRANSPORTER
SUGAR BINDING
PROTEIN

(Xanthomonas
citri) 		PF13416
(SBP_bac_8) 		4 ALA A 295
LEU A 200
ALA A 368
ASN A  89
 None
 0.92A 3b6hA-3uorA:
undetectable		 3b6hA-3uorA:
22.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3v8d CHOLESTEROL
7-ALPHA-MONOOXYGENAS
E

(Homo sapiens) 		PF00067
(p450) 		4 ALA A 218
LEU A 219
ALA A 231
THR A 230
 None
 0.82A 3b6hA-3v8dA:
44.0		 3b6hA-3v8dA:
36.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w5n PUTATIVE
RHAMNOSIDASE

(Streptomyces
avermitilis) 		PF05592
(Bac_rhamnosid)
PF08531
(Bac_rhamnosid_N)
PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C) 		4 ALA A 540
LEU A 542
ALA A 528
ASN A 506
 None
 0.76A 3b6hA-3w5nA:
undetectable		 3b6hA-3w5nA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wc3 ENDO-1,
4-BETA-GLUCANASE

(Eisenia fetida) 		PF00759
(Glyco_hydro_9) 		4 TYR A 256
ALA A 255
LEU A 252
ALA A 285
 None
 0.92A 3b6hA-3wc3A:
undetectable		 3b6hA-3wc3A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wky PROPHENOLOXIDASE B

(Marsupenaeus
japonicus) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 TYR A 520
ALA A 521
LEU A 524
THR A 410
 None
 0.84A 3b6hA-3wkyA:
undetectable		 3b6hA-3wkyA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wz3 TRAM PROTEIN

(Plasmid R64) 		PF11393
(T4BSS_DotI_IcmL) 		5 ALA A 137
LEU A 138
ALA A 107
THR A 106
ASN A 109
 None
 1.29A 3b6hA-3wz3A:
undetectable		 3b6hA-3wz3A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x27 CUCUMOPINE SYNTHASE

(Marinactinospora
thermotolerans) 		no annotation 4 TYR A 289
ALA A 290
LEU A 293
THR A 254
 None
 0.71A 3b6hA-3x27A:
undetectable		 3b6hA-3x27A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4az7 BETA-N-ACETYLHEXOSAM
INIDASE

(Streptococcus
pneumoniae) 		PF00728
(Glyco_hydro_20) 		4 TYR A 397
ALA A 398
LEU A 401
THR A 291
 None
 0.88A 3b6hA-4az7A:
undetectable		 3b6hA-4az7A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dth VGRG PROTEIN

(Vibrio cholerae) 		PF16671
(ACD) 		4 ALA A  20
LEU A  19
ALA A 103
THR A 104
 None
 0.88A 3b6hA-4dthA:
undetectable		 3b6hA-4dthA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4edq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MYOSIN-BINDI
NG PROTEIN C,
CARDIAC-TYPE
CHIMERIC PROTEIN

(Escherichia
coli;
Mus musculus) 		PF07679
(I-set)
PF13416
(SBP_bac_8) 		4 ALA A 189
LEU A 193
ALA A 347
THR A 346
 None
 0.91A 3b6hA-4edqA:
undetectable		 3b6hA-4edqA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4egc MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HOMEOBOX PROTEIN
SIX1 CHIMERA

(Escherichia
coli;
Homo sapiens) 		PF00046
(Homeobox)
PF13416
(SBP_bac_8)
PF16878
(SIX1_SD) 		4 ALA A 188
LEU A 192
ALA A 346
THR A 345
 None
 0.86A 3b6hA-4egcA:
undetectable		 3b6hA-4egcA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fq7 MALEATE CIS-TRANS
ISOMERASE

(Pseudomonas
putida) 		no annotation 4 ALA A 118
LEU A 121
ALA A 199
THR A 137
 None
 0.82A 3b6hA-4fq7A:
undetectable		 3b6hA-4fq7A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwt THREONINE--TRNA
LIGASE, CYTOPLASMIC

(Homo sapiens) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon) 		4 ALA A 388
LEU A 389
THR A 638
ASN A 640
 None
 0.92A 3b6hA-4hwtA:
undetectable		 3b6hA-4hwtA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4imd N-ACETYLNEURAMINATE
LYASE

(Pasteurella
multocida) 		PF00701
(DHDPS) 		4 TYR A  94
ALA A  95
LEU A  98
ALA A  66
 None
 0.76A 3b6hA-4imdA:
undetectable		 3b6hA-4imdA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kv3 CHIMERA FUSION
PROTEIN OF ESX-1
SECRETION SYSTEM
PROTEIN ECCD1 AND
MALTOSE-BINDING
PERIPLASMIC PROTEIN

(Escherichia
coli;
Mycobacterium
tuberculosis) 		PF08817
(YukD)
PF13416
(SBP_bac_8) 		4 ALA A 189
LEU A 193
ALA A 347
THR A 346
 None
 0.88A 3b6hA-4kv3A:
undetectable		 3b6hA-4kv3A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lls GERANYLTRANSTRANSFER
ASE

(Roseobacter
denitrificans) 		PF00348
(polyprenyl_synt) 		4 ALA A 137
LEU A 140
ALA A  68
THR A  67
 None
 0.91A 3b6hA-4llsA:
2.3		 3b6hA-4llsA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4llv 4E10 FV HEAVY CHAIN

(Homo sapiens) 		PF07686
(V-set) 		4 TYR A  32
ALA A  33
LEU A  34
ALA A  71
 None
 0.90A 3b6hA-4llvA:
undetectable		 3b6hA-4llvA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m9x CELL DEATH PROTEIN 4

(Caenorhabditis
elegans) 		PF00619
(CARD)
PF00931
(NB-ARC) 		4 ALA A  84
LEU A  83
ALA A  13
THR A  12
 None
 0.81A 3b6hA-4m9xA:
undetectable		 3b6hA-4m9xA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4my2 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
NORRIN FUSION
PROTEIN

(Escherichia
coli;
Homo sapiens) 		PF00007
(Cys_knot)
PF13416
(SBP_bac_8) 		4 ALA A 190
LEU A 194
ALA A 348
THR A 347
 None
 0.92A 3b6hA-4my2A:
undetectable		 3b6hA-4my2A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nec PUTATIVE
SAM-DEPENDENT
METHYLTRANSFERASE

(Streptomyces
lasaliensis) 		PF13649
(Methyltransf_25) 		4 TYR A 125
ALA A 126
LEU A 129
ALA A 139
 None
 0.72A 3b6hA-4necA:
undetectable		 3b6hA-4necA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4neg TRYPTOPHAN SYNTHASE
BETA CHAIN

(Bacillus
anthracis) 		PF00291
(PALP) 		4 TYR A 361
ALA A 362
LEU A 365
ALA A 230
 None
 0.85A 3b6hA-4negA:
undetectable		 3b6hA-4negA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p3g SIGNAL RECOGNITION
PARTICLE SUBUNIT
SRP68

(Chaetomium
thermophilum) 		PF16969
(SRP68) 		4 ALA A 139
LEU A 142
ALA A  73
THR A  72
 None
 0.62A 3b6hA-4p3gA:
undetectable		 3b6hA-4p3gA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pe2 MALTOSE ABC
TRANSPORTER
PERIPLASMIC
PROTEIN,PREPILIN-TYP
E N-TERMINAL
CLEAVAGE/METHYLATION
DOMAIN PROTEIN

(Clostridioides
difficile;
Escherichia
coli) 		PF13416
(SBP_bac_8) 		4 ALA A 188
LEU A 192
ALA A 346
THR A 345
 None
 0.89A 3b6hA-4pe2A:
undetectable		 3b6hA-4pe2A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfy ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF00496
(SBP_bac_5) 		4 TYR A 418
ALA A 419
LEU A 422
ASN A 276
 None
None
None
BMA  A 607 ( 4.9A)
 0.81A 3b6hA-4pfyA:
undetectable		 3b6hA-4pfyA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r2w URIDINE
PHOSPHORYLASE

(Shewanella
oneidensis) 		PF01048
(PNP_UDP_1) 		5 TYR A  53
ALA A  52
LEU A  51
ALA A  16
THR A  17
 None
 1.33A 3b6hA-4r2wA:
undetectable		 3b6hA-4r2wA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rwf MALTOSE TRANSPORTER
SUBUNIT, RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 2,
CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
FUSION PROTEIN

(Escherichia
coli;
Homo sapiens) 		PF02793
(HRM)
PF04901
(RAMP)
PF13416
(SBP_bac_8) 		4 ALA A 190
LEU A 194
ALA A 348
THR A 347
 None
 0.89A 3b6hA-4rwfA:
undetectable		 3b6hA-4rwfA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wut ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)

(Agrobacterium
vitis) 		PF13407
(Peripla_BP_4) 		4 ALA A 261
LEU A 259
ALA A 223
THR A 222
 None
 0.92A 3b6hA-4wutA:
undetectable		 3b6hA-4wutA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wvi MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SIGNAL
PEPTIDASE IB

(Escherichia
coli;
Staphylococcus
aureus) 		PF00717
(Peptidase_S24)
PF13416
(SBP_bac_8) 		4 ALA A 194
LEU A 198
ALA A 352
THR A 351
 None
 0.89A 3b6hA-4wviA:
undetectable		 3b6hA-4wviA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wy5 ESTERASE

(Rhizomucor
miehei) 		PF07859
(Abhydrolase_3) 		4 TYR A 271
ALA A 272
LEU A 275
THR A 185
 None
 0.75A 3b6hA-4wy5A:
undetectable		 3b6hA-4wy5A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9n L-ALPHA-GLYCEROPHOSP
HATE OXIDASE

(Mycoplasma
pneumoniae) 		PF01266
(DAO) 		4 TYR A 215
LEU A 219
THR A 192
ASN A 194
 None
 0.89A 3b6hA-4x9nA:
undetectable		 3b6hA-4x9nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a1n BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE

(Homo sapiens) 		PF00043
(GST_C) 		4 ALA A  20
LEU A  19
ALA A 126
THR A 127
 None
 0.89A 3b6hA-5a1nA:
undetectable		 3b6hA-5a1nA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5btb AFR263CP

(Eremothecium
gossypii) 		PF08652
(RAI1) 		4 ALA A 341
LEU A   9
ALA A 121
THR A 122
 None
 0.89A 3b6hA-5btbA:
undetectable		 3b6hA-5btbA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c7r FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND TYPE-3
ICE-STRUCTURING
PROTEIN HPLC 12

(Escherichia
coli;
Zoarces
americanus) 		PF01547
(SBP_bac_1) 		4 ALA A 188
LEU A 192
ALA A 346
THR A 345
 None
 0.92A 3b6hA-5c7rA:
undetectable		 3b6hA-5c7rA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cx8 LIPOPROTEIN RAGB

(Porphyromonas
gingivalis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 TYR A 234
ALA A 235
LEU A 238
ALA A 157
 None
 0.54A 3b6hA-5cx8A:
0.6		 3b6hA-5cx8A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dfm MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TELOMERASE-A
SSOCIATED PROTEIN 19

(Escherichia
coli;
Tetrahymena
thermophila) 		PF13416
(SBP_bac_8) 		4 ALA A 188
LEU A 192
ALA A 346
THR A 345
 None
 0.92A 3b6hA-5dfmA:
undetectable		 3b6hA-5dfmA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f4l ENVELOPE
GLYCOPROTEIN GP120
OF HIV-1 CLADE C

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		4 TYR A 217
LEU A 215
ALA A  70
THR A  71
 None
 0.83A 3b6hA-5f4lA:
undetectable		 3b6hA-5f4lA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fsg MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HANTAVIRUS
NUCLEOPROTEIN

(Hantaan
orthohantavirus) 		PF00846
(Hanta_nucleocap)
PF13416
(SBP_bac_8) 		4 ALA A-184
LEU A-180
ALA A -26
THR A -27
 None
 0.77A 3b6hA-5fsgA:
undetectable		 3b6hA-5fsgA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g4i PHOSPHOLYASE

(Paenarthrobacter
aurescens) 		PF00202
(Aminotran_3) 		4 TYR A  99
ALA A 100
LEU A 103
ALA A 291
 None
 0.70A 3b6hA-5g4iA:
undetectable		 3b6hA-5g4iA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h68 CHROMOSOME PARTITION
PROTEIN SMC

(Geobacillus
stearothermophilus) 		PF02463
(SMC_N) 		4 TYR A1131
ALA A1132
LEU A1135
ALA A  28
 None
 0.89A 3b6hA-5h68A:
undetectable		 3b6hA-5h68A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hh3 OXYA PROTEIN

(Actinoplanes
teichomyceticus) 		PF00067
(p450) 		4 ALA A 348
LEU A 347
ALA A 148
THR A 147
 HEM  A 401 ( 4.0A)
HEM  A 401 (-4.3A)
None
None
 0.87A 3b6hA-5hh3A:
24.1		 3b6hA-5hh3A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hl4 RING-HYDROXYLATING
DIOXYGENASE

(Sinorhizobium
meliloti) 		PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A) 		4 TYR A  32
ALA A  33
LEU A  36
ALA A  66
 None
 0.69A 3b6hA-5hl4A:
undetectable		 3b6hA-5hl4A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN

(Escherichia
coli;
Homo sapiens) 		PF00100
(Zona_pellucida)
PF13416
(SBP_bac_8) 		4 ALA A 555
LEU A 559
ALA A 713
THR A 712
 None
 0.92A 3b6hA-5hzvA:
undetectable		 3b6hA-5hzvA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN

(Paraburkholderia
phymatum) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 ALA A  90
LEU A  89
ALA A  32
THR A  33
 None
 0.86A 3b6hA-5iduA:
0.0		 3b6hA-5iduA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE

(Escherichia
coli;
Homo sapiens) 		no annotation 4 ALA C 188
LEU C 192
ALA C 346
THR C 345
 None
 0.87A 3b6hA-5jj4C:
undetectable		 3b6hA-5jj4C:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jon MALTOSE-BINDING
PERIPLASMIC
PROTEIN,POTASSIUM/SO
DIUM
HYPERPOLARIZATION-AC
TIVATED CYCLIC
NUCLEOTIDE-GATED
CHANNEL 2

(Escherichia
coli;
Mus musculus) 		PF00027
(cNMP_binding)
PF13416
(SBP_bac_8) 		4 ALA A-181
LEU A-177
ALA A -23
THR A -24
 None
 0.89A 3b6hA-5jonA:
undetectable		 3b6hA-5jonA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lc5 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
3

(Bos taurus) 		PF00146
(NADHdh)
PF00507
(Oxidored_q4) 		4 ALA H  82
LEU H  83
ALA A  14
THR A  15
 None
 0.79A 3b6hA-5lc5H:
undetectable		 3b6hA-5lc5H:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m1t MUCR
PHOSPHODIESTERASE

(Pseudomonas
aeruginosa) 		PF00563
(EAL) 		4 ALA A 607
LEU A 605
ALA A 566
THR A 565
 None
 0.87A 3b6hA-5m1tA:
undetectable		 3b6hA-5m1tA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ttd MALTOSE-BINDING
PERIPLASMIC
PROTEIN,PILIN
ISOPEPTIDE LINKAGE
DOMAIN PROTEIN

(Escherichia
coli;
Streptococcus
pyogenes) 		PF12892
(FctA)
PF13416
(SBP_bac_8) 		4 ALA A 194
LEU A 198
ALA A 352
THR A 351
 None
 0.89A 3b6hA-5ttdA:
undetectable		 3b6hA-5ttdA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u2o J30 CCH

(Thermobacillus
composti) 		no annotation 4 TYR A 384
ALA A 385
LEU A 388
ALA A 418
 None
 0.83A 3b6hA-5u2oA:
undetectable		 3b6hA-5u2oA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5waq OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMD

(Neisseria
gonorrhoeae) 		no annotation 4 TYR A 110
ALA A 111
LEU A 114
ALA A  79
 None
 0.73A 3b6hA-5waqA:
undetectable		 3b6hA-5waqA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b1z GLUTAMATE--TRNA
LIGASE

(Elizabethkingia
anophelis) 		PF00749
(tRNA-synt_1c) 		4 ALA A  61
LEU A  62
ALA A  24
THR A  23
 None
None
None
FMT  A 608 ( 4.4A)
 0.87A 3b6hA-6b1zA:
undetectable		 3b6hA-6b1zA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6du8 -

(-) 		no annotation 4 ALA A 287
LEU A 288
ALA A 244
THR A 243
 None
 0.92A 3b6hA-6du8A:
undetectable		 3b6hA-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fwv -

(-) 		no annotation 4 TYR A  89
ALA A  90
LEU A  93
ALA A 109
 None
None
None
ZN  A 601 ( 4.4A)
 0.80A 3b6hA-6fwvA:
undetectable		 3b6hA-6fwvA:
undetectable