SIMILAR PATTERNS OF AMINO ACIDS FOR 3B0W_B_DGXB1_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a05 | 3-ISOPROPYLMALATEDEHYDROGENASE (Acidithiobacillusferrooxidans) |
PF00180(Iso_dh) | 5 | GLN A 22LEU A 354ALA A 19VAL A 320HIS A 278 | None | 1.25A | 3b0wB-1a05A:0.0 | 3b0wB-1a05A:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cj0 | PROTEIN (SERINEHYDROXYMETHYLTRANSFERASE) (Oryctolaguscuniculus) |
PF00464(SHMT) | 5 | CYH A 344ALA A 368ALA A 417LEU A 362LEU A 302 | None | 1.36A | 3b0wB-1cj0A:0.6 | 3b0wB-1cj0A:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fn9 | OUTER-CAPSID PROTEINSIGMA 3 (Reovirus sp.) |
PF00979(Reovirus_cap) | 5 | GLN A 10LEU A 315CYH A 51ALA A 48ALA A 314 | NoneNone ZN A1001 (-2.3A)NoneNone | 1.31A | 3b0wB-1fn9A:0.0 | 3b0wB-1fn9A:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ftg | APOFLAVODOXIN (Nostoc sp. PCC7119) |
PF00258(Flavodoxin_1) | 5 | LEU A 163CYH A 54ALA A 19LEU A 62LEU A 69 | None | 1.32A | 3b0wB-1ftgA:undetectable | 3b0wB-1ftgA:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hfe | PROTEIN (FE-ONLYHYDROGENASE(E.C.1.18.99.1)(LARGER SUBUNIT)) (Desulfovibriovulgaris) |
PF02906(Fe_hyd_lg_C)PF13237(Fer4_10) | 5 | LEU L 134MET L 105ALA L 104LEU L 242LEU L 246 | None | 1.09A | 3b0wB-1hfeL:undetectable | 3b0wB-1hfeL:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1igw | ISOCITRATE LYASE (Escherichiacoli) |
PF00463(ICL) | 5 | LEU A 229ALA A 209ALA A 283VAL A 286PHE A 301 | None | 1.21A | 3b0wB-1igwA:0.0 | 3b0wB-1igwA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k8g | TELOMERE-BINDINGPROTEIN ALPHASUBUNIT (Sterkiella nova) |
PF02765(POT1) | 5 | LEU A 41CYH A 74ALA A 138ALA A 56VAL A 58 | None | 1.03A | 3b0wB-1k8gA:0.0 | 3b0wB-1k8gA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1krh | BENZOATE1,2-DIOXYGENASEREDUCTASE (Acinetobactersp.) |
PF00111(Fer2)PF00175(NAD_binding_1)PF00970(FAD_binding_6) | 5 | GLN A 230LEU A 259ALA A 255VAL A 254LEU A 185 | None | 1.09A | 3b0wB-1krhA:undetectable | 3b0wB-1krhA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) |
PF00478(IMPDH) | 5 | GLN A 84LEU A 250ALA A 236VAL A 234LEU A 443 | None | 1.29A | 3b0wB-1lrtA:0.0 | 3b0wB-1lrtA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mew | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) |
PF00478(IMPDH)PF00571(CBS) | 5 | GLN A 84LEU A 250ALA A 236VAL A 234LEU A 443 | None | 1.33A | 3b0wB-1mewA:undetectable | 3b0wB-1mewA:17.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1nq7 | NUCLEAR RECEPTORROR-BETA (Rattusnorvegicus) |
PF00104(Hormone_recep) | 5 | GLN A 228CYH A 262ALA A 269LEU A 333HIS A 423 | ARL A 800 (-4.7A)ARL A 800 (-3.5A)ARL A 800 ( 3.9A)NoneARL A 800 ( 4.3A) | 1.16A | 3b0wB-1nq7A:28.9 | 3b0wB-1nq7A:49.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1nq7 | NUCLEAR RECEPTORROR-BETA (Rattusnorvegicus) |
PF00104(Hormone_recep) | 10 | GLN A 228LEU A 234CYH A 262ALA A 269MET A 307ALA A 310VAL A 318PHE A 330LEU A 333LEU A 338 | ARL A 800 (-4.7A)NoneARL A 800 (-3.5A)ARL A 800 ( 3.9A)ARL A 800 (-3.7A)ARL A 800 ( 4.1A)NoneARL A 800 (-3.6A)NoneARL A 800 ( 4.8A) | 0.83A | 3b0wB-1nq7A:28.9 | 3b0wB-1nq7A:49.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1nq7 | NUCLEAR RECEPTORROR-BETA (Rattusnorvegicus) |
PF00104(Hormone_recep) | 6 | GLN A 228LEU A 237CYH A 262PHE A 330LEU A 333LEU A 338 | ARL A 800 (-4.7A)NoneARL A 800 (-3.5A)ARL A 800 (-3.6A)NoneARL A 800 ( 4.8A) | 1.23A | 3b0wB-1nq7A:28.9 | 3b0wB-1nq7A:49.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1nq7 | NUCLEAR RECEPTORROR-BETA (Rattusnorvegicus) |
PF00104(Hormone_recep) | 8 | LEU A 234CYH A 262ALA A 269MET A 307ALA A 310VAL A 318PHE A 330LEU A 258 | NoneARL A 800 (-3.5A)ARL A 800 ( 3.9A)ARL A 800 (-3.7A)ARL A 800 ( 4.1A)NoneARL A 800 (-3.6A)None | 1.50A | 3b0wB-1nq7A:28.9 | 3b0wB-1nq7A:49.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sxj | ACTIVATOR 1 37 KDASUBUNITACTIVATOR 1 40 KDASUBUNIT (Saccharomycescerevisiae) |
PF00004(AAA)PF08542(Rep_fac_C) | 5 | GLN B 8CYH C 144VAL C 37PHE C 51LEU C 146 | None | 1.32A | 3b0wB-1sxjB:undetectable | 3b0wB-1sxjB:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tdj | BIOSYNTHETICTHREONINE DEAMINASE (Escherichiacoli) |
PF00291(PALP)PF00585(Thr_dehydrat_C) | 5 | LEU A 409CYH A 356ALA A 339VAL A 383LEU A 448 | None | 1.26A | 3b0wB-1tdjA:undetectable | 3b0wB-1tdjA:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1txz | HYPOTHETICAL 32.1KDA PROTEIN INADH3-RCA1 INTERGENICREGION (Saccharomycescerevisiae) |
PF14519(Macro_2) | 5 | LEU A 188ALA A 120MET A 179PHE A 171LEU A 235 | None | 1.32A | 3b0wB-1txzA:undetectable | 3b0wB-1txzA:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v02 | DHURRINASE (Sorghum bicolor) |
PF00232(Glyco_hydro_1) | 5 | CYH A 194MET A 300ALA A 304VAL A 308LEU A 232 | None | 1.29A | 3b0wB-1v02A:undetectable | 3b0wB-1v02A:17.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v19 | 2-KETO-3-DEOXYGLUCONATE KINASE (Thermusthermophilus) |
PF00294(PfkB) | 5 | LEU A 123MET A 150ALA A 153VAL A 160LEU A 180 | None | 1.31A | 3b0wB-1v19A:undetectable | 3b0wB-1v19A:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v8d | HYPOTHETICAL PROTEIN(TT1679) (Thermusthermophilus) |
PF04260(DUF436) | 5 | GLN A 110LEU A 163ALA A 167PHE A 54LEU A 191 | None | 1.30A | 3b0wB-1v8dA:undetectable | 3b0wB-1v8dA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vl4 | PMBA-RELATED PROTEIN (Thermotogamaritima) |
PF01523(PmbA_TldD) | 5 | LEU A 346ALA A 422MET A 227VAL A 427LEU A 401 | None | 1.14A | 3b0wB-1vl4A:undetectable | 3b0wB-1vl4A:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vm7 | RIBOKINASE (Thermotogamaritima) |
PF00294(PfkB) | 5 | ALA A 244ALA A 238VAL A 236PHE A 295LEU A 296 | None | 1.23A | 3b0wB-1vm7A:undetectable | 3b0wB-1vm7A:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ytm | PHOSPHOENOLPYRUVATECARBOXYKINASE [ATP] (Anaerobiospirillumsucciniciproducens) |
PF01293(PEPCK_ATP) | 5 | MET A 423ALA A 428VAL A 351PHE A 241LEU A 378 | None | 1.29A | 3b0wB-1ytmA:undetectable | 3b0wB-1ytmA:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z6t | APOPTOTIC PROTEASEACTIVATING FACTOR 1 (Homo sapiens) |
PF00619(CARD)PF00931(NB-ARC) | 5 | LEU A 415VAL A 395LEU A 487LEU A 473HIS A 468 | None | 1.35A | 3b0wB-1z6tA:undetectable | 3b0wB-1z6tA:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zcj | PEROXISOMALBIFUNCTIONAL ENZYME (Rattusnorvegicus) |
PF00725(3HCDH)PF02737(3HCDH_N) | 5 | LEU A 708ALA A 630ALA A 667PHE A 511LEU A 508 | None | 1.29A | 3b0wB-1zcjA:undetectable | 3b0wB-1zcjA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bb0 | IMIDAZOLONEPROPIONASE (Bacillussubtilis) |
PF01979(Amidohydro_1) | 5 | LEU A 199MET A 182ALA A 184LEU A 273LEU A 294 | None | 1.36A | 3b0wB-2bb0A:undetectable | 3b0wB-2bb0A:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cb1 | O-ACETYL HOMOSERINESULFHYDRYLASE (Thermusthermophilus) |
PF01053(Cys_Met_Meta_PP) | 5 | GLN A 228LEU A 222ALA A 172VAL A 174LEU A 111 | None | 1.27A | 3b0wB-2cb1A:undetectable | 3b0wB-2cb1A:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eq9 | PYRUVATEDEHYDROGENASECOMPLEX,DIHYDROLIPOAMIDEDEHYDROGENASE E3COMPONENT (Thermusthermophilus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | LEU A 175ALA A 62ALA A 200VAL A 202LEU A 223 | None | 1.35A | 3b0wB-2eq9A:undetectable | 3b0wB-2eq9A:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gb4 | THIOPURINES-METHYLTRANSFERASE (Mus musculus) |
PF05724(TPMT) | 5 | LEU A 230CYH A 211ALA A 178ALA A 217HIS A 47 | None | 1.24A | 3b0wB-2gb4A:undetectable | 3b0wB-2gb4A:23.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gnw | NON-SYMBIOTICHEMOGLOBIN 1 (Oryza sativa) |
PF00042(Globin) | 5 | GLN A 87LEU A 101ALA A 156VAL A 154LEU A 126 | NoneNoneNoneHEM A 166 (-4.4A)None | 1.29A | 3b0wB-2gnwA:undetectable | 3b0wB-2gnwA:24.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j7n | RNA-DEPENDENT RNAPOLYMERASE (Neurosporacrassa) |
PF05183(RdRP) | 5 | ALA A 786ALA A 918VAL A1015PHE A 991LEU A 930 | None | 1.33A | 3b0wB-2j7nA:undetectable | 3b0wB-2j7nA:12.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pvu | ARTJ (Geobacillusstearothermophilus) |
PF00497(SBP_bac_3) | 5 | MET A 54ALA A 222VAL A 219PHE A 209LEU A 75 | None | 1.16A | 3b0wB-2pvuA:undetectable | 3b0wB-2pvuA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r5v | PCZA361.1 (Amycolatopsisorientalis) |
PF00903(Glyoxalase)PF14696(Glyoxalase_5) | 5 | LEU A 52ALA A 243VAL A 75PHE A 119LEU A 166 | None CO A4113 ( 4.4A)NoneNoneNone | 1.34A | 3b0wB-2r5vA:undetectable | 3b0wB-2r5vA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vo1 | CTP SYNTHASE 1 (Homo sapiens) |
PF06418(CTP_synth_N) | 5 | LEU A 130ALA A 129VAL A 125PHE A 163LEU A 209 | None | 1.28A | 3b0wB-2vo1A:undetectable | 3b0wB-2vo1A:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x3e | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 (Pseudomonasaeruginosa) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | LEU A 97ALA A 67ALA A 60PHE A 114LEU A 306 | None | 1.30A | 3b0wB-2x3eA:undetectable | 3b0wB-2x3eA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yjq | CEL44C (Paenibacilluspolymyxa) |
PF12891(Glyco_hydro_44) | 5 | LEU A 407ALA A 490ALA A 510VAL A 451PHE A 464 | None | 1.30A | 3b0wB-2yjqA:undetectable | 3b0wB-2yjqA:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zie | PUTATIVEMODIFICATIONMETHYLASE (Thermusthermophilus) |
PF01555(N6_N4_Mtase) | 5 | LEU A 222ALA A 244ALA A 252VAL A 229LEU A 87 | None | 1.22A | 3b0wB-2zieA:undetectable | 3b0wB-2zieA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aat | ASPARTATEAMINOTRANSFERASE (Escherichiacoli) |
PF00155(Aminotran_1_2) | 5 | LEU A 20CYH A 401ALA A 381VAL A 387PHE A 337 | None | 1.23A | 3b0wB-3aatA:undetectable | 3b0wB-3aatA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ahr | ERO1-LIKE PROTEINALPHA (Homo sapiens) |
PF04137(ERO1) | 5 | LEU A 415ALA A 446ALA A 314VAL A 318LEU A 329 | None | 1.28A | 3b0wB-3ahrA:undetectable | 3b0wB-3ahrA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3all | 2-METHYL-3-HYDROXYPYRIDINE-5-CARBOXYLICACID OXYGENASE (Mesorhizobiumjaponicum) |
PF01494(FAD_binding_3) | 5 | LEU A 325ALA A 14ALA A 284VAL A 286LEU A 113 | None | 1.23A | 3b0wB-3allA:undetectable | 3b0wB-3allA:24.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b4w | ALDEHYDEDEHYDROGENASE (Mycobacteriumtuberculosis) |
PF00171(Aldedh) | 5 | TRP A 110ALA A 168ALA A 152VAL A 154LEU A 94 | None | 1.05A | 3b0wB-3b4wA:undetectable | 3b0wB-3b4wA:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b9p | CG5977-PA, ISOFORM A (Drosophilamelanogaster) |
PF00004(AAA)PF09336(Vps4_C) | 5 | LEU A 520ALA A 626VAL A 624PHE A 568LEU A 470 | None | 1.17A | 3b0wB-3b9pA:undetectable | 3b0wB-3b9pA:24.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3crr | TRNADELTA(2)-ISOPENTENYLPYROPHOSPHATETRANSFERASE (Pseudomonasaeruginosa) |
PF01715(IPPT) | 5 | GLN A 288LEU A 216ALA A 15LEU A 33LEU A 57 | TRS A 327 ( 4.9A)NoneDPO A 326 (-4.6A)NoneNone | 1.30A | 3b0wB-3crrA:undetectable | 3b0wB-3crrA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dc8 | DIHYDROPYRIMIDINASE (Sinorhizobiummeliloti) |
PF01979(Amidohydro_1) | 5 | GLN A 406ALA A 403ALA A 316PHE A 289HIS A 279 | None | 1.19A | 3b0wB-3dc8A:undetectable | 3b0wB-3dc8A:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e5b | ISOCITRATE LYASE (Brucellaabortus) |
PF00463(ICL) | 5 | LEU A 203ALA A 221VAL A 220PHE A 341LEU A 332 | None | 1.33A | 3b0wB-3e5bA:undetectable | 3b0wB-3e5bA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e9n | PUTATIVE SHORT-CHAINDEHYDROGENASE/REDUCTASE (Corynebacteriumglutamicum) |
PF00106(adh_short) | 5 | LEU A 42ALA A 80ALA A 31VAL A 29LEU A 119 | None | 1.21A | 3b0wB-3e9nA:undetectable | 3b0wB-3e9nA:17.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3feo | MBTDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF02820(MBT) | 5 | CYH A 303ALA A 243VAL A 245PHE A 285LEU A 281 | None | 1.32A | 3b0wB-3feoA:undetectable | 3b0wB-3feoA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gjb | CYTC3 (Streptomycessp.) |
PF05721(PhyH) | 5 | LEU A 226ALA A 258ALA A 231VAL A 29PHE A 12 | None | 1.36A | 3b0wB-3gjbA:undetectable | 3b0wB-3gjbA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gqj | CELL INHIBITINGFACTOR (CIF) (Photorhabduslaumondii) |
PF16374(CIF) | 5 | LEU A 278ALA A 172VAL A 174LEU A 208LEU A 211 | None | 1.08A | 3b0wB-3gqjA:undetectable | 3b0wB-3gqjA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7f | SERINEHYDROXYMETHYLTRANSFERASE 1 (Mycobacteriumtuberculosis) |
PF00464(SHMT) | 5 | ALA A 218VAL A 197PHE A 202LEU A 205LEU A 229 | None | 1.36A | 3b0wB-3h7fA:undetectable | 3b0wB-3h7fA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i45 | TWIN-ARGININETRANSLOCATIONPATHWAY SIGNALPROTEIN (Rhodospirillumrubrum) |
PF13458(Peripla_BP_6) | 5 | LEU A 165MET A 132ALA A 131VAL A 365LEU A 327 | None | 1.35A | 3b0wB-3i45A:undetectable | 3b0wB-3i45A:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i8b | XYLULOSE KINASE (Bifidobacteriumadolescentis) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | LEU A 324TRP A 169MET A 276ALA A 275LEU A 67 | None | 1.18A | 3b0wB-3i8bA:undetectable | 3b0wB-3i8bA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iuk | UNCHARACTERIZEDPROTEIN (Paenarthrobacteraurescens) |
PF05960(DUF885) | 5 | LEU A 558ALA A 557VAL A 553LEU A 88LEU A 67 | None | 1.29A | 3b0wB-3iukA:undetectable | 3b0wB-3iukA:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l6d | PUTATIVEOXIDOREDUCTASE (Pseudomonasputida) |
PF03446(NAD_binding_2) | 5 | GLN A 31MET A 24ALA A 25VAL A 14HIS A 143 | None | 1.31A | 3b0wB-3l6dA:undetectable | 3b0wB-3l6dA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lg3 | ISOCITRATE LYASE (Yersinia pestis) |
PF00463(ICL) | 5 | LEU A 230ALA A 210ALA A 284VAL A 287PHE A 302 | None | 1.13A | 3b0wB-3lg3A:undetectable | 3b0wB-3lg3A:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lhq | ACRAB OPERONREPRESSOR (TETR/ACRRFAMILY) (Salmonellaenterica) |
PF00440(TetR_N)PF08361(TetR_C_2) | 5 | ALA A 129VAL A 126PHE A 59LEU A 21LEU A 17 | None | 1.29A | 3b0wB-3lhqA:undetectable | 3b0wB-3lhqA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lm6 | STAGE V SPORULATIONPROTEIN AD (Bacillussubtilis) |
PF07451(SpoVAD) | 5 | LEU A 81ALA A 185VAL A 171PHE A 291LEU A 294 | None | 1.24A | 3b0wB-3lm6A:undetectable | 3b0wB-3lm6A:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3men | ACETYLPOLYAMINEAMINOHYDROLASE (Burkholderiapseudomallei) |
PF00850(Hist_deacetyl) | 5 | GLN A 9CYH A 167ALA A 149VAL A 315HIS A 62 | NoneSO4 A 401 ( 4.2A)NoneNoneNone | 1.14A | 3b0wB-3menA:undetectable | 3b0wB-3menA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rfe | PLATELETGLYCOPROTEIN IB BETACHAIN (Homo sapiens) |
PF01463(LRRCT) | 5 | TRP A 21ALA A 52VAL A 12LEU A 42LEU A 61 | None | 1.30A | 3b0wB-3rfeA:undetectable | 3b0wB-3rfeA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s1s | RESTRICTIONENDONUCLEASE BPUSI (Bacilluspumilus) |
PF02384(N6_Mtase)PF15516(BpuSI_N) | 5 | LEU A 448ALA A 463VAL A 511LEU A 560LEU A 540 | None | 1.35A | 3b0wB-3s1sA:undetectable | 3b0wB-3s1sA:14.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wx7 | CHITINOLIGOSACCHARIDEDEACETYLASE (Vibrioparahaemolyticus) |
PF01522(Polysacc_deac_1) | 5 | ALA A 256VAL A 253PHE A 314LEU A 311LEU A 243 | None | 0.91A | 3b0wB-3wx7A:undetectable | 3b0wB-3wx7A:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wxx | ACRHAOPB (Aeromonashydrophila) |
PF04888(SseC)no annotation | 5 | ALA B 235ALA B 178VAL B 175LEU A 74LEU A 86 | None | 1.31A | 3b0wB-3wxxB:undetectable | 3b0wB-3wxxB:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4anj | UNCONVENTIONALMYOSIN-VI, GREENFLUORESCENT PROTEIN (Aequoreavictoria;Sus scrofa) |
PF00063(Myosin_head)PF01353(GFP) | 5 | LEU A 378ALA A 255ALA A 342VAL A 341PHE A 192 | None | 1.18A | 3b0wB-4anjA:undetectable | 3b0wB-4anjA:13.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b8c | GLUCOSE-REPRESSIBLEALCOHOLDEHYDROGENASETRANSCRIPTIONALEFFECTOR (Saccharomycescerevisiae) |
PF03372(Exo_endo_phos)PF13855(LRR_8) | 5 | LEU D 171ALA D 136ALA D 168LEU D 152HIS D 145 | None | 1.33A | 3b0wB-4b8cD:undetectable | 3b0wB-4b8cD:15.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bev | COPPER EFFLUX ATPASE (Legionellapneumophila) |
PF00122(E1-E2_ATPase)PF00702(Hydrolase) | 5 | LEU A 511MET A 539VAL A 504LEU A 481LEU A 479 | None | 1.32A | 3b0wB-4bevA:undetectable | 3b0wB-4bevA:15.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bif | CUPIN 2 CONSERVEDBARREL DOMAINPROTEIN (Granulicellatundricola) |
PF07883(Cupin_2) | 5 | ALA A 117ALA A 40VAL A 42PHE A 19HIS A 94 | NoneNoneNoneNone MN A1132 (-3.6A) | 1.24A | 3b0wB-4bifA:undetectable | 3b0wB-4bifA:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4efc | ADENYLOSUCCINATELYASE (Trypanosomabrucei) |
PF00206(Lyase_1)PF08328(ASL_C) | 5 | ALA A 161ALA A 36LEU A 272LEU A 336HIS A 280 | None | 1.04A | 3b0wB-4efcA:undetectable | 3b0wB-4efcA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gni | PUTATIVE HEAT SHOCKPROTEIN (Chaetomiumthermophilum) |
PF00012(HSP70) | 5 | LEU A 146ALA A 395ALA A 142VAL A 139LEU A 169 | None | 1.20A | 3b0wB-4gniA:undetectable | 3b0wB-4gniA:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gni | PUTATIVE HEAT SHOCKPROTEIN (Chaetomiumthermophilum) |
PF00012(HSP70) | 5 | LEU A 146ALA A 398ALA A 142VAL A 139LEU A 169 | None | 1.20A | 3b0wB-4gniA:undetectable | 3b0wB-4gniA:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ina | SACCHAROPINEDEHYDROGENASE (Wolinellasuccinogenes) |
PF03435(Sacchrp_dh_NADP)PF16653(Sacchrp_dh_C) | 5 | GLN A 6LEU A 104ALA A 17MET A 352ALA A 355 | None | 1.33A | 3b0wB-4inaA:undetectable | 3b0wB-4inaA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mgg | MUCONATE LACTONIZINGENZYME (Labrenziaaggregata) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | CYH A 50ALA A 303ALA A 275VAL A 269LEU A 53 | None | 1.25A | 3b0wB-4mggA:undetectable | 3b0wB-4mggA:18.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nz5 | DEACETYLASE DA1 (Vibrio cholerae) |
PF01522(Polysacc_deac_1) | 5 | ALA A 260VAL A 257PHE A 318LEU A 315LEU A 247 | None | 0.92A | 3b0wB-4nz5A:undetectable | 3b0wB-4nz5A:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4paf | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT, PUTATIVE (Ruegeriapomeroyi) |
PF03480(DctP) | 5 | ALA A 44MET A 261ALA A 262VAL A 142LEU A 85 | None | 1.17A | 3b0wB-4pafA:undetectable | 3b0wB-4pafA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4paf | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT, PUTATIVE (Ruegeriapomeroyi) |
PF03480(DctP) | 5 | MET A 261ALA A 262VAL A 142LEU A 77LEU A 85 | None | 1.31A | 3b0wB-4pafA:undetectable | 3b0wB-4pafA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pvv | ADENOSINE KINASE (Mycobacteriumtuberculosis) |
PF00294(PfkB) | 5 | LEU A 66ALA A 151ALA A 50VAL A 49LEU A 174 | NoneNoneNoneHO4 A 401 (-4.5A)None | 1.28A | 3b0wB-4pvvA:undetectable | 3b0wB-4pvvA:21.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4s15 | NUCLEAR RECEPTORROR-ALPHA (Homo sapiens) |
PF00104(Hormone_recep) | 5 | GLN A 289CYH A 323ALA A 330LEU A 394HIS A 484 | 4D8 A 601 ( 2.7A)4D8 A 601 ( 4.0A)4D8 A 601 (-3.1A)4D8 A 601 ( 4.5A)None | 0.98A | 3b0wB-4s15A:30.7 | 3b0wB-4s15A:53.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4s15 | NUCLEAR RECEPTORROR-ALPHA (Homo sapiens) |
PF00104(Hormone_recep) | 6 | GLN A 289LEU A 295ALA A 330ALA A 371VAL A 379LEU A 394 | 4D8 A 601 ( 2.7A)None4D8 A 601 (-3.1A)4D8 A 601 ( 4.0A)None4D8 A 601 ( 4.5A) | 1.36A | 3b0wB-4s15A:30.7 | 3b0wB-4s15A:53.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4s15 | NUCLEAR RECEPTORROR-ALPHA (Homo sapiens) |
PF00104(Hormone_recep) | 9 | GLN A 289LEU A 295CYH A 323ALA A 330MET A 368ALA A 371VAL A 379PHE A 391LEU A 394 | 4D8 A 601 ( 2.7A)None4D8 A 601 ( 4.0A)4D8 A 601 (-3.1A)4D8 A 601 (-4.0A)4D8 A 601 ( 4.0A)None4D8 A 601 ( 4.5A)4D8 A 601 ( 4.5A) | 0.46A | 3b0wB-4s15A:30.7 | 3b0wB-4s15A:53.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ubt | ACETYL-COAACETYLTRANSFERASEFADA5 (Mycobacteriumtuberculosis) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | LEU A 268CYH A 118ALA A 41VAL A 38LEU A 30 | None | 1.34A | 3b0wB-4ubtA:undetectable | 3b0wB-4ubtA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yr1 | ALKALINE PHOSPHATASE (Escherichiacoli) |
PF00245(Alk_phosphatase) | 5 | LEU A 120ALA A 157VAL A 160LEU A 310LEU A 255 | None | 1.22A | 3b0wB-4yr1A:undetectable | 3b0wB-4yr1A:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aff | SYMPORTIN 1 (Chaetomiumthermophilum) |
no annotation | 5 | LEU A 152ALA A 59ALA A 94LEU A 166LEU A 115 | None | 1.21A | 3b0wB-5affA:undetectable | 3b0wB-5affA:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c1b | TRANSITIONALENDOPLASMICRETICULUM ATPASE (Homo sapiens) |
PF00004(AAA)PF02359(CDC48_N)PF02933(CDC48_2)PF09336(Vps4_C) | 5 | LEU A 242ALA A 310ALA A 345VAL A 343PHE A 290 | None | 1.26A | 3b0wB-5c1bA:undetectable | 3b0wB-5c1bA:15.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5c4t | NUCLEAR RECEPTORROR-GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 10 | GLN A 286LEU A 292CYH A 320ALA A 327MET A 365ALA A 368VAL A 376PHE A 388LEU A 391LEU A 396 | NoneNoneGOL A 607 ( 4.0A)NoneNoneNoneNoneGOL A 607 ( 4.5A)NoneNone | 0.61A | 3b0wB-5c4tA:34.2 | 3b0wB-5c4tA:99.59 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5c4t | NUCLEAR RECEPTORROR-GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 11 | GLN A 286LEU A 292TRP A 317CYH A 320ALA A 327ALA A 368VAL A 376PHE A 388LEU A 391LEU A 396HIS A 479 | NoneNoneNoneGOL A 607 ( 4.0A)NoneNoneNoneGOL A 607 ( 4.5A)NoneNoneNone | 0.52A | 3b0wB-5c4tA:34.2 | 3b0wB-5c4tA:99.59 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5c4t | NUCLEAR RECEPTORROR-GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 287TRP A 317PHE A 388LEU A 391LEU A 396HIS A 479 | NoneNoneGOL A 607 ( 4.5A)NoneNoneNone | 1.17A | 3b0wB-5c4tA:34.2 | 3b0wB-5c4tA:99.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dlj | CRISPR-ASSOCIATEDENDONUCLEASE CAS1 (Escherichiacoli) |
no annotation | 5 | GLN D 90ALA D 94ALA D 50VAL D 15LEU D 272 | None | 1.07A | 3b0wB-5dljD:undetectable | 3b0wB-5dljD:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5euf | PROTEASE (Helicobacterpylori) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 5 | LEU A 330VAL A 283PHE A 432LEU A 362LEU A 424 | None | 1.26A | 3b0wB-5eufA:undetectable | 3b0wB-5eufA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5g | PUTATIVE XANTHINEDEHYDROGENASE YAGSFAD-BINDING SUBUNIT (Escherichiacoli) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 5 | GLN C 287LEU C 336CYH C 696ALA C 360LEU C 401 | NoneACT C1740 ( 4.5A)NoneNoneNone | 1.16A | 3b0wB-5g5gC:undetectable | 3b0wB-5g5gC:13.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hdt | SISTER CHROMATIDCOHESION PROTEINPDS5 HOMOLOG B (Homo sapiens) |
no annotation | 5 | LEU A 998ALA A 958MET A 940ALA A 941VAL A 991 | None | 1.25A | 3b0wB-5hdtA:undetectable | 3b0wB-5hdtA:11.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringae groupgenomosp. 3) |
no annotation | 5 | LEU A 231CYH A 175ALA A 181VAL A 219LEU A 94 | None | 1.28A | 3b0wB-5iuwA:undetectable | 3b0wB-5iuwA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k1c | WD REPEAT-CONTAININGPROTEIN 48 (Homo sapiens) |
PF00400(WD40) | 5 | CYH B 109ALA B 104ALA B 48VAL B 78LEU B 113 | None | 1.15A | 3b0wB-5k1cB:undetectable | 3b0wB-5k1cB:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lst | ATP-DEPENDENT DNAHELICASE Q4 (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C) | 5 | LEU A 937ALA A 587VAL A 627LEU A 596LEU A 577 | None | 1.11A | 3b0wB-5lstA:undetectable | 3b0wB-5lstA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mb9 | PUTATIVE HEAT SHOCKPROTEIN (Chaetomiumthermophilum) |
PF00012(HSP70) | 5 | LEU A 146ALA A 395ALA A 142VAL A 139LEU A 169 | None | 1.24A | 3b0wB-5mb9A:undetectable | 3b0wB-5mb9A:16.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mg5 | 2,4-DIACETYLPHLOROGLUCINOL BIOSYNTHESISPROTEIN PHLC (Pseudomonasprotegens) |
no annotation | 5 | CYH C 112ALA C 34MET C 43ALA C 41VAL C 9 | None | 1.29A | 3b0wB-5mg5C:undetectable | 3b0wB-5mg5C:13.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wbl | REGULATORY-ASSOCIATED PROTEIN OF TOR 1 (Arabidopsisthaliana) |
no annotation | 5 | LEU A1264ALA A1236VAL A1219LEU A1186LEU A1197 | None | 1.15A | 3b0wB-5wblA:undetectable | 3b0wB-5wblA:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wgx | FLAVIN-DEPENDENTHALOGENASE (Malbrancheaaurantiaca) |
PF04820(Trp_halogenase) | 5 | LEU A 382ALA A 230VAL A 324PHE A 259LEU A 116 | FAD A 701 ( 4.7A)FAD A 701 (-3.6A)NoneNoneNone | 1.35A | 3b0wB-5wgxA:undetectable | 3b0wB-5wgxA:16.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xi0 | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] (Aliivibriofischeri) |
no annotation | 5 | LEU A 129ALA A 98VAL A 44PHE A 312LEU A 309 | None | 1.08A | 3b0wB-5xi0A:undetectable | 3b0wB-5xi0A:15.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6chs | PUTATIVE CELLDIVISION CONTROLPROTEIN (Chaetomiumthermophilum) |
no annotation | 5 | LEU H 258ALA H 326ALA H 361VAL H 359PHE H 306 | None | 1.24A | 3b0wB-6chsH:undetectable | 3b0wB-6chsH:15.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6et9 | ACETYL-COAACETYLTRANSFERASETHIOLASE (Methanothermococcusthermolithotrophicus) |
no annotation | 5 | LEU A 73ALA A 215ALA A 71PHE A 22LEU A 17 | None | 1.15A | 3b0wB-6et9A:undetectable | 3b0wB-6et9A:15.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f8z | ALPHA-1,2-MANNOSIDASE, PUTATIVE (Bacteroidesthetaiotaomicron) |
no annotation | 5 | LEU A 621MET A 650ALA A 649VAL A 646LEU A 676 | None | 1.26A | 3b0wB-6f8zA:undetectable | 3b0wB-6f8zA:15.00 |