SIMILAR PATTERNS OF AMINO ACIDS FOR 3AVP_A_MV2A313

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)


(Escherichia
coli)
PF00117
(GATase)
PF00988
(CPSase_sm_chain)
4 VAL B1530
ASP B1511
LEU B1622
ILE B1610
None
0.92A 3avpA-1a9xB:
undetectable
3avpA-1a9xB:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b1y PROTEIN
(BETA-AMYLASE)


(Hordeum vulgare)
PF01373
(Glyco_hydro_14)
4 VAL A 361
ASP A 346
ILE A 392
ASN A 395
None
1.02A 3avpA-1b1yA:
0.0
3avpA-1b1yA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1btc BETA-AMYLASE

(Glycine max)
PF01373
(Glyco_hydro_14)
4 VAL A 363
ASP A 348
ILE A 394
ASN A 397
BME  A 504 (-4.5A)
None
None
None
0.97A 3avpA-1btcA:
0.0
3avpA-1btcA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1exb KV BETA2 PROTEIN

(Rattus
norvegicus)
PF00248
(Aldo_ket_red)
4 VAL A 114
LEU A  47
ILE A  81
ASN A  82
None
1.02A 3avpA-1exbA:
0.0
3avpA-1exbA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gq7 PROCLAVAMINATE
AMIDINO HYDROLASE


(Streptomyces
clavuligerus)
PF00491
(Arginase)
4 VAL A 140
ASP A 276
HIS A 121
ILE A 168
None
None
MN  A 350 (-3.3A)
None
0.99A 3avpA-1gq7A:
0.0
3avpA-1gq7A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1htq GLUTAMINE SYNTHETASE

(Mycobacterium
tuberculosis)
PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N)
4 ASP A  70
HIS A 230
ILE A 116
ASN A 113
None
1.02A 3avpA-1htqA:
undetectable
3avpA-1htqA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kon PROTEIN YEBC

(Escherichia
coli)
PF01709
(Transcrip_reg)
4 VAL A 163
ASP A 167
TYR A 173
ILE A 201
None
1.01A 3avpA-1konA:
0.0
3avpA-1konA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE


(Bacillus
subtilis)
PF08282
(Hydrolase_3)
4 VAL A  48
ASP A   9
HIS A  17
ILE A  57
None
PO4  A 900 ( 3.6A)
None
None
1.04A 3avpA-1nrwA:
0.0
3avpA-1nrwA:
20.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sq5 PANTOTHENATE KINASE

(Escherichia
coli)
PF00485
(PRK)
5 VAL A1097
ASP A1127
HIS A1177
LEU A1201
ASN A1282
ADP  A5001 ( 4.4A)
PAU  A6001 (-2.9A)
PAU  A6001 (-4.2A)
None
PAU  A6001 (-3.0A)
1.00A 3avpA-1sq5A:
37.1
3avpA-1sq5A:
52.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sq5 PANTOTHENATE KINASE

(Escherichia
coli)
PF00485
(PRK)
5 VAL A1097
ASP A1127
LEU A1201
TYR A1240
ASN A1282
ADP  A5001 ( 4.4A)
PAU  A6001 (-2.9A)
None
PAU  A6001 (-4.3A)
PAU  A6001 (-3.0A)
0.92A 3avpA-1sq5A:
37.1
3avpA-1sq5A:
52.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yni SUCCINYLARGININE
DIHYDROLASE


(Escherichia
coli)
PF04996
(AstB)
4 VAL A 195
LEU A 193
ILE A 252
ASN A 249
None
0.81A 3avpA-1yniA:
undetectable
3avpA-1yniA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yq9 PERIPLASMIC [NIFE]
HYDROGENASE SMALL
SUBUNIT


(Desulfovibrio
gigas)
PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C)
4 VAL A  24
HIS A  13
LEU A  25
ILE A  40
None
1.04A 3avpA-1yq9A:
undetectable
3avpA-1yq9A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z2o INOSITOL
1,3,4-TRISPHOSPHATE
5/6-KINASE


(Entamoeba
histolytica)
PF05770
(Ins134_P3_kin)
4 HIS X  88
LEU X  13
TYR X 296
ILE X 183
None
0.98A 3avpA-1z2oX:
undetectable
3avpA-1z2oX:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a62 CADHERIN-8

(Mus musculus)
PF00028
(Cadherin)
4 VAL A  96
ASP A 101
TYR A  71
ILE A  47
None
CA  A 325 ( 2.7A)
None
None
1.00A 3avpA-2a62A:
undetectable
3avpA-2a62A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b0t NADP ISOCITRATE
DEHYDROGENASE


(Corynebacterium
glutamicum)
PF03971
(IDH)
4 VAL A 127
ASP A  10
TYR A 124
ILE A 105
None
0.92A 3avpA-2b0tA:
3.2
3avpA-2b0tA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1i PEPTIDOGLYCAN GLCNAC
DEACETYLASE


(Streptococcus
pneumoniae)
PF01522
(Polysacc_deac_1)
4 ASP A 276
HIS A 330
LEU A 415
ILE A 370
ZN  A1465 ( 2.3A)
ZN  A1465 ( 3.2A)
None
None
0.97A 3avpA-2c1iA:
undetectable
3avpA-2c1iA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dlt MYOSIN BINDING
PROTEIN C, FAST-TYPE


(Mus musculus)
PF07679
(I-set)
4 VAL A  32
HIS A  58
LEU A   9
ILE A  15
None
0.91A 3avpA-2dltA:
undetectable
3avpA-2dltA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eq9 PYRUVATE
DEHYDROGENASE
COMPLEX,
DIHYDROLIPOAMIDE
DEHYDROGENASE E3
COMPONENT


(Thermus
thermophilus)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 VAL A 400
ASP A 407
HIS A 461
LEU A 409
None
0.98A 3avpA-2eq9A:
undetectable
3avpA-2eq9A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fff PENICILLIN-BINDING
PROTEIN 1B


(Streptococcus
pneumoniae)
PF00905
(Transpeptidase)
4 HIS B 567
LEU B 620
TYR B 608
ILE B 470
None
0.97A 3avpA-2fffB:
undetectable
3avpA-2fffB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fjl 1-PHOSPHATIDYLINOSIT
OL-4,5-BISPHOSPHATE
PHOSPHODIESTERASE
GAMMA 1


(Rattus
norvegicus)
PF00169
(PH)
4 VAL A  23
ASP A  80
TYR A  21
ASN A   4
None
1.01A 3avpA-2fjlA:
undetectable
3avpA-2fjlA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2glj PROBABLE M18-FAMILY
AMINOPEPTIDASE 1


(Clostridium
acetobutylicum)
PF02127
(Peptidase_M18)
4 ASP A 342
HIS A 105
LEU A 437
TYR A 262
MN  A6002 (-2.0A)
MN  A6002 (-3.4A)
None
None
1.03A 3avpA-2gljA:
undetectable
3avpA-2gljA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iw0 CHITIN DEACETYLASE

(Colletotrichum
lindemuthianum)
PF01522
(Polysacc_deac_1)
4 ASP A  50
HIS A 108
LEU A 204
ILE A 163
ZN  A1255 ( 2.5A)
ZN  A1255 ( 3.2A)
None
None
0.88A 3avpA-2iw0A:
undetectable
3avpA-2iw0A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j7m HYALURONIDASE

(Clostridium
perfringens)
PF00754
(F5_F8_type_C)
4 VAL A 763
LEU A 674
TYR A 687
ILE A 698
None
1.00A 3avpA-2j7mA:
undetectable
3avpA-2j7mA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jb1 L-AMINO ACID OXIDASE

(Rhodococcus
opacus)
PF01593
(Amino_oxidase)
4 VAL A 261
LEU A 301
TYR A 275
ILE A 284
FAD  A1489 (-3.7A)
None
None
None
1.04A 3avpA-2jb1A:
undetectable
3avpA-2jb1A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jch PENICILLIN-BINDING
PROTEIN 1B


(Streptococcus
pneumoniae)
PF00905
(Transpeptidase)
PF00912
(Transgly)
4 HIS A 567
LEU A 620
TYR A 608
ILE A 470
None
1.02A 3avpA-2jchA:
undetectable
3avpA-2jchA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ly2 TUDOR
DOMAIN-CONTAINING
PROTEIN 7


(Mus musculus)
PF12872
(OST-HTH)
4 VAL A 295
HIS A  -1
LEU A 291
ILE A 305
None
0.83A 3avpA-2ly2A:
undetectable
3avpA-2ly2A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nrj HBL B PROTEIN

(Bacillus cereus)
PF05791
(Bacillus_HBL)
4 VAL A 254
ASP A 181
ILE A 220
ASN A  46
None
1.05A 3avpA-2nrjA:
undetectable
3avpA-2nrjA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2odl ADHESIN

(Haemophilus
influenzae)
PF05860
(Haemagg_act)
4 VAL A 146
LEU A 140
ILE A 100
ASN A 126
None
1.05A 3avpA-2odlA:
undetectable
3avpA-2odlA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2quq CENTROMERE
DNA-BINDING PROTEIN
COMPLEX CBF3 SUBUNIT
B


(Saccharomyces
cerevisiae)
PF16846
(Cep3)
4 VAL A 477
ASP A 423
LEU A  58
ILE A 470
None
0.96A 3avpA-2quqA:
undetectable
3avpA-2quqA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rb5 PUTATIVE
UNCHARACTERIZED
PROTEIN


(Bacteroides
thetaiotaomicron)
PF08282
(Hydrolase_3)
4 VAL A  14
ASP A 211
ILE A  50
ASN A  52
None
MG  A 701 (-2.5A)
None
None
0.95A 3avpA-2rb5A:
undetectable
3avpA-2rb5A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v5d O-GLCNACASE NAGJ

(Clostridium
perfringens)
PF00754
(F5_F8_type_C)
PF02838
(Glyco_hydro_20b)
PF07555
(NAGidase)
4 VAL A 763
LEU A 674
TYR A 687
ILE A 698
None
0.93A 3avpA-2v5dA:
undetectable
3avpA-2v5dA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vrc TRIPHENYLMETHANE
REDUCTASE


(Citrobacter sp.
MY-5)
PF05368
(NmrA)
4 HIS A  19
LEU A 267
TYR A 143
ASN A 140
None
1.02A 3avpA-2vrcA:
undetectable
3avpA-2vrcA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xvr MAJOR CAPSID PROTEIN
10A


(Escherichia
virus T7)
no annotation 4 VAL A 298
LEU A 303
ILE A 239
ASN A 241
None
0.92A 3avpA-2xvrA:
undetectable
3avpA-2xvrA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbm PROTEIN-TYROSINE-PHO
SPHATASE


(Shewanella sp.)
PF00149
(Metallophos)
4 VAL A 154
ASP A 114
HIS A  80
TYR A 177
None
ZN  A 402 ( 2.8A)
ZN  A 401 (-3.2A)
None
1.00A 3avpA-2zbmA:
undetectable
3avpA-2zbmA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3av3 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE


(Geobacillus
kaustophilus)
PF00551
(Formyl_trans_N)
4 VAL A  35
LEU A  33
TYR A  89
ILE A  93
None
1.01A 3avpA-3av3A:
undetectable
3avpA-3av3A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ay3 NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E


(Chromohalobacter
salexigens)
PF01370
(Epimerase)
4 VAL A 201
ASP A 144
TYR A 203
ILE A 123
None
0.96A 3avpA-3ay3A:
undetectable
3avpA-3ay3A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b8l UNCHARACTERIZED
PROTEIN


(Novosphingobium
aromaticivorans)
PF13577
(SnoaL_4)
4 VAL A  94
ASP A  23
LEU A  75
ILE A  46
None
0.91A 3avpA-3b8lA:
undetectable
3avpA-3b8lA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjx HALOCARBOXYLIC ACID
DEHALOGENASE DEHI


(Pseudomonas
putida)
PF10778
(DehI)
4 VAL A 103
ASP A 284
LEU A 107
ILE A 202
None
0.91A 3avpA-3bjxA:
undetectable
3avpA-3bjxA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE


(Rhodobacter
sphaeroides)
PF04952
(AstE_AspA)
4 ASP A 146
HIS A 148
LEU A 133
ILE A  99
None
CA  A 401 (-3.3A)
None
None
0.98A 3avpA-3cdxA:
undetectable
3avpA-3cdxA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fmc PUTATIVE
SUCCINYLGLUTAMATE
DESUCCINYLASE /
ASPARTOACYLASE


(Shewanella
amazonensis)
PF04952
(AstE_AspA)
4 ASP A 169
HIS A 171
LEU A 157
ILE A  79
None
0.84A 3avpA-3fmcA:
undetectable
3avpA-3fmcA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gb4 DDMC

(Stenotrophomonas
maltophilia)
PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A)
4 ASP A 294
HIS A 165
LEU A 155
ASN A 230
CO  A 502 (-1.9A)
CO  A 502 (-3.3A)
None
D3M  A 601 (-2.8A)
1.00A 3avpA-3gb4A:
undetectable
3avpA-3gb4A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iv3 TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 2


(Streptococcus
mutans)
PF01791
(DeoC)
4 VAL A 213
LEU A 256
TYR A 214
ASN A 211
None
None
None
EDO  A 334 (-3.5A)
0.98A 3avpA-3iv3A:
undetectable
3avpA-3iv3A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k5s CADHERIN-13

(Gallus gallus)
PF00028
(Cadherin)
4 VAL A  97
ASP A 102
TYR A  73
ILE A  49
VAL  A  97 ( 0.6A)
ASP  A 102 ( 0.6A)
TYR  A  73 ( 1.3A)
ILE  A  49 ( 0.6A)
0.79A 3avpA-3k5sA:
undetectable
3avpA-3k5sA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kq4 GASTRIC INTRINSIC
FACTOR


(Homo sapiens)
PF01122
(Cobalamin_bind)
PF14478
(DUF4430)
4 VAL A 346
LEU A 347
ILE A 333
ASN A 334
None
1.03A 3avpA-3kq4A:
undetectable
3avpA-3kq4A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY


(Desulfitobacterium
hafniense)
PF04016
(DUF364)
PF13938
(DUF4213)
4 VAL A 128
ASP A 180
LEU A 158
ILE A 196
None
IMD  A 303 ( 2.8A)
IMD  A 303 (-4.2A)
None
0.98A 3avpA-3l5oA:
undetectable
3avpA-3l5oA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lu2 LMO2462 PROTEIN

(Listeria
monocytogenes)
PF01244
(Peptidase_M19)
4 ASP A   9
HIS A   7
ILE A 142
ASN A 133
ZN  A 310 (-2.7A)
ZN  A 310 (-4.5A)
None
None
1.04A 3avpA-3lu2A:
undetectable
3avpA-3lu2A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lwu SUCCINYLGLUTAMATE
DESUCCINYLASE/ASPART
OACYLASE


(Shewanella
frigidimarina)
PF04952
(AstE_AspA)
4 ASP A 171
HIS A 173
LEU A 159
ILE A  81
None
ZN  A 374 (-3.1A)
None
None
0.91A 3avpA-3lwuA:
undetectable
3avpA-3lwuA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwu SERINE PROTEASE
HTRA1


(Homo sapiens)
PF13365
(Trypsin_2)
4 VAL A 221
HIS A 185
ILE A 342
ASN A 218
None
None
None
SO4  A   1 (-3.0A)
1.06A 3avpA-3nwuA:
undetectable
3avpA-3nwuA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppe VASCULAR ENDOTHELIAL
CADHERIN


(Gallus gallus)
PF00028
(Cadherin)
4 VAL A  94
ASP A  99
TYR A  69
ILE A  45
None
CA  A 401 ( 2.6A)
None
None
0.88A 3avpA-3ppeA:
undetectable
3avpA-3ppeA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ros NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE


(Lactobacillus
acidophilus)
PF00171
(Aldedh)
4 VAL A 148
LEU A 443
ILE A 125
ASN A 145
None
1.04A 3avpA-3rosA:
undetectable
3avpA-3rosA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s25 HYPOTHETICAL
7-BLADED
BETA-PROPELLER-LIKE
PROTEIN


([Eubacterium]
rectale)
PF16472
(DUF5050)
4 VAL A  35
ASP A  53
ILE A 164
ASN A  31
EDO  A 332 (-4.5A)
EDO  A 332 (-2.9A)
None
None
1.04A 3avpA-3s25A:
undetectable
3avpA-3s25A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sim PROTEIN, FAMILY 18
CHITINASE


(Crocus vernus)
PF00704
(Glyco_hydro_18)
4 VAL A   4
LEU A   2
TYR A   6
ASN A 184
None
0.87A 3avpA-3simA:
undetectable
3avpA-3simA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sub ADP-RIBOSYLATION
FACTOR
GTPASE-ACTIVATING
PROTEIN


(Plasmodium
falciparum)
PF01412
(ArfGap)
4 ASP A  24
HIS A  49
LEU A  87
ILE A 135
None
0.87A 3avpA-3subA:
undetectable
3avpA-3subA:
20.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3tqc PANTOTHENATE KINASE

(Coxiella
burnetii)
PF00485
(PRK)
4 VAL A  98
ASP A 128
HIS A 178
LEU A 202
ADP  A 500 ( 4.4A)
None
None
None
0.89A 3avpA-3tqcA:
37.3
3avpA-3tqcA:
51.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3tqc PANTOTHENATE KINASE

(Coxiella
burnetii)
PF00485
(PRK)
4 VAL A  98
HIS A 178
LEU A 202
ASN A 283
ADP  A 500 ( 4.4A)
None
None
None
0.69A 3avpA-3tqcA:
37.3
3avpA-3tqcA:
51.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3tqc PANTOTHENATE KINASE

(Coxiella
burnetii)
PF00485
(PRK)
4 VAL A  98
LEU A 202
TYR A 241
ASN A 283
ADP  A 500 ( 4.4A)
None
None
None
0.37A 3avpA-3tqcA:
37.3
3avpA-3tqcA:
51.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zg6 NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-6


(Homo sapiens)
PF02146
(SIR2)
4 VAL A 259
HIS A 266
LEU A  28
ILE A 209
None
1.00A 3avpA-3zg6A:
undetectable
3avpA-3zg6A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a5o BIFUNCTIONAL PROTEIN
FOLD


(Pseudomonas
aeruginosa)
PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C)
4 VAL A 171
ASP A 121
ILE A 232
ASN A 169
None
1.04A 3avpA-4a5oA:
2.7
3avpA-4a5oA:
26.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c23 L-FUCULOSE KINASE
FUCK


(Streptococcus
pneumoniae)
PF00370
(FGGY_N)
PF02782
(FGGY_C)
4 VAL A 370
LEU A 348
TYR A 371
ILE A 317
None
0.94A 3avpA-4c23A:
undetectable
3avpA-4c23A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dq6 PUTATIVE PYRIDOXAL
PHOSPHATE-DEPENDENT
TRANSFERASE


(Clostridioides
difficile)
PF00155
(Aminotran_1_2)
4 ASP A 259
TYR A  69
ILE A  73
ASN A  70
None
1.06A 3avpA-4dq6A:
undetectable
3avpA-4dq6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ep0 MAJOR TAIL PROTEIN

(Streptococcus
virus C1)
PF16838
(Caud_tail_N)
4 VAL A 553
ASP A 110
LEU A 548
ILE A 517
None
1.05A 3avpA-4ep0A:
undetectable
3avpA-4ep0A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdy SIMILAR TO
LIPOPROTEIN, NLP/P60
FAMILY


(Staphylococcus
aureus)
PF00877
(NLPC_P60)
PF13702
(Lysozyme_like)
4 VAL A 198
ASP A 131
TYR A 197
ILE A  79
None
1.01A 3avpA-4fdyA:
undetectable
3avpA-4fdyA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g56 MGC81050 PROTEIN

(Xenopus laevis)
PF00400
(WD40)
4 VAL B  24
HIS B 314
LEU B  34
ILE B 264
None
1.04A 3avpA-4g56B:
undetectable
3avpA-4g56B:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k0e HEAVY METAL CATION
TRICOMPONENT EFFLUX
PUMP ZNEA(CZCA-LIKE)


(Cupriavidus
metallidurans)
PF00873
(ACR_tran)
4 ASP A 393
LEU A 997
ILE A 930
ASN A 927
None
1.00A 3avpA-4k0eA:
undetectable
3avpA-4k0eA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kk7 ESX-1 SECRETION
SYSTEM PROTEIN ECCB1


(Mycobacterium
tuberculosis)
PF05108
(T7SS_ESX1_EccB)
4 VAL A 361
HIS A 204
LEU A 181
ILE A 228
None
0.98A 3avpA-4kk7A:
undetectable
3avpA-4kk7A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE


(Bacillus cereus)
PF01522
(Polysacc_deac_1)
4 ASP A  81
HIS A 135
LEU A 223
ILE A 175
ACT  A 302 ( 4.0A)
PXU  A 171 (-3.6A)
None
None
0.98A 3avpA-4l1gA:
undetectable
3avpA-4l1gA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE


(Bacillus cereus)
PF01522
(Polysacc_deac_1)
4 ASP A  81
HIS A 135
LEU A 223
ILE A 190
ACT  A 302 ( 4.0A)
PXU  A 171 (-3.6A)
None
None
0.91A 3avpA-4l1gA:
undetectable
3avpA-4l1gA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ml1 DSBP

(Klebsiella
pneumoniae)
PF10411
(DsbC_N)
PF13098
(Thioredoxin_2)
4 VAL A 198
ASP A  66
HIS A  72
ILE A 185
None
1.04A 3avpA-4ml1A:
undetectable
3avpA-4ml1A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n7t PHOSPHOPENTOMUTASE

(Streptococcus
mutans)
PF01676
(Metalloenzyme)
4 VAL A  70
ASP A 318
LEU A  48
ILE A  61
None
1.05A 3avpA-4n7tA:
undetectable
3avpA-4n7tA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nhy 2-OXOGLUTARATE AND
IRON-DEPENDENT
OXYGENASE
DOMAIN-CONTAINING
PROTEIN 1


(Homo sapiens)
PF10637
(Ofd1_CTDD)
PF13661
(2OG-FeII_Oxy_4)
4 VAL A 197
ASP A  57
HIS A  63
ILE A 187
None
0.96A 3avpA-4nhyA:
undetectable
3avpA-4nhyA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oh1 L-IDITOL
2-DEHYDROGENASE


([Clostridium]
scindens)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 VAL A 160
HIS A  73
LEU A 184
ILE A 298
None
ZN  A 401 (-3.5A)
None
None
0.72A 3avpA-4oh1A:
undetectable
3avpA-4oh1A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4om9 SERINE PROTEASE PET

(Escherichia
coli)
PF02395
(Peptidase_S6)
4 ASP A 522
HIS A 519
TYR A 471
ILE A 443
None
0.63A 3avpA-4om9A:
undetectable
3avpA-4om9A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oou BETA-1,4-MANNANASE

(Cryptopygus
antarcticus)
no annotation 4 ASP B 233
LEU B 237
TYR B  32
ILE B 381
None
0.99A 3avpA-4oouB:
undetectable
3avpA-4oouB:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oy2 TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 7


(Saccharomyces
cerevisiae)
PF04658
(TAFII55_N)
5 VAL B 292
LEU B 296
TYR B 288
ILE B 227
ASN B 230
None
1.23A 3avpA-4oy2B:
undetectable
3avpA-4oy2B:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r0k DIPEPTIDYL-PEPTIDASE
VI


(Bacteroides
thetaiotaomicron)
PF00877
(NLPC_P60)
4 VAL A 130
LEU A  58
TYR A 112
ILE A 189
None
1.03A 3avpA-4r0kA:
undetectable
3avpA-4r0kA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rk2 PUTATIVE SUGAR ABC
TRANSPORTER,
SUBSTRATE-BINDING
PROTEIN


(Rhizobium etli)
PF01547
(SBP_bac_1)
4 VAL A 203
ASP A 176
LEU A 196
ILE A 402
None
1.01A 3avpA-4rk2A:
undetectable
3avpA-4rk2A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rt6 HEME/HEMOPEXIN-BINDI
NG PROTEIN


(Haemophilus
influenzae)
PF05860
(Haemagg_act)
4 VAL A  82
LEU A  76
ILE A  36
ASN A  62
None
1.05A 3avpA-4rt6A:
undetectable
3avpA-4rt6A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rxx UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 38


(Homo sapiens)
no annotation 4 VAL A  60
ASP A  54
LEU A  48
ILE A  21
None
1.05A 3avpA-4rxxA:
undetectable
3avpA-4rxxA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yub NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE


(Homo sapiens)
no annotation 4 ASP A 288
HIS A 213
LEU A 324
ILE A 358
None
1.02A 3avpA-4yubA:
undetectable
3avpA-4yubA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ywg HEAVY CHAIN OF
ANTI-HIV-1 GP120
V1V2 ANTIBODY 830A


(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
4 VAL H  24
ASP H 101
LEU H   4
ILE H  71
None
0.89A 3avpA-4ywgH:
undetectable
3avpA-4ywgH:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b04 PROBABLE TRANSLATION
INITIATION FACTOR
EIF-2B SUBUNIT
EPSILON


(Schizosaccharomyces
pombe)
PF00132
(Hexapep)
PF00483
(NTP_transferase)
4 VAL I 230
ASP I 122
HIS I 143
ILE I 243
None
1.00A 3avpA-5b04I:
undetectable
3avpA-5b04I:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5et1 ESPIN
MYOSIN-IIIB


(Mus musculus)
PF12796
(Ank_2)
PF13637
(Ank_4)
PF13857
(Ank_5)
no annotation
4 ASP A  33
HIS A  42
TYR C1268
ASN A  69
None
0.94A 3avpA-5et1A:
undetectable
3avpA-5et1A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i08 SPIKE GLYCOPROTEIN,
ENVELOPE
GLYCOPROTEIN CHIMERA


(Human
coronavirus
HKU1;
Human
immunodeficiency
virus 1)
PF01601
(Corona_S2)
PF09408
(Spike_rec_bind)
PF16451
(Spike_NTD)
4 VAL A 363
ASP A 328
LEU A 359
ILE A 588
None
1.04A 3avpA-5i08A:
undetectable
3avpA-5i08A:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iu9 PROTOCADHERIN-19
ISOFORM 1


(Danio rerio)
PF00028
(Cadherin)
PF08266
(Cadherin_2)
4 VAL A 205
ASP A 210
TYR A 181
ILE A 150
None
CA  A1004 ( 2.5A)
None
None
0.75A 3avpA-5iu9A:
undetectable
3avpA-5iu9A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j4a IMMUNITY PROTEIN
CDII


(Burkholderia
pseudomallei)
no annotation 4 VAL B  42
LEU B  59
TYR B  43
ILE B  27
None
0.99A 3avpA-5j4aB:
undetectable
3avpA-5j4aB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjo UNCHARACTERIZED
PROTEIN


(Pseudomonas
aeruginosa)
PF08238
(Sel1)
4 VAL A  51
ASP A 262
TYR A  47
ASN A  83
None
1.01A 3avpA-5jjoA:
undetectable
3avpA-5jjoA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jvf SITE-DETERMINING
PROTEIN


(Pseudomonas
aeruginosa)
PF10609
(ParA)
4 VAL A 149
ASP A 127
ILE A 214
ASN A 181
None
None
None
IOD  A 311 (-4.3A)
1.03A 3avpA-5jvfA:
undetectable
3avpA-5jvfA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE DELTA
SUBUNIT
ACETOPHENONE
CARBOXYLASE GAMMA
SUBUNIT


(Aromatoleum
aromaticum)
PF01968
(Hydantoinase_A)
PF02538
(Hydantoinase_B)
PF05378
(Hydant_A_N)
4 VAL B 367
ASP B 394
HIS B 478
ILE A  36
None
0.91A 3avpA-5l9wB:
undetectable
3avpA-5l9wB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lw7 ABC TRANSPORTER
ATP-BINDING PROTEIN


(Pyrococcus
abyssi)
PF00005
(ABC_tran)
PF00037
(Fer4)
PF04068
(RLI)
4 VAL B 420
LEU B 458
TYR B 451
ILE B 448
None
1.05A 3avpA-5lw7B:
1.8
3avpA-5lw7B:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o6y PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE


(Bacillus cereus)
no annotation 4 ASP B  81
HIS B 135
LEU B 223
ILE B 190
5YA  B 302 ( 2.5A)
ZN  B 303 ( 3.7A)
None
None
0.94A 3avpA-5o6yB:
undetectable
3avpA-5o6yB:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vxl INVASIN IPAD
SINGLE-DOMAIN
ANTIBODY JPS-G3


(Shigella
flexneri;
Vicugna pacos)
PF06511
(IpaD)
no annotation
4 VAL A 170
LEU A 174
TYR B  54
ILE B  31
None
0.98A 3avpA-5vxlA:
undetectable
3avpA-5vxlA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xgo DNA PROTECTION
DURING STARVATION
PROTEIN,BACTERIOFERR
ITIN


(Escherichia
coli)
no annotation 4 VAL A 114
ASP A 167
LEU A 118
ILE A  60
None
1.01A 3avpA-5xgoA:
undetectable
3avpA-5xgoA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xk2 DIACYLGLYCEROL
LIPASE


(Aspergillus
oryzae)
no annotation 4 VAL A  77
ASP A  38
TYR A 145
ASN A  79
None
1.03A 3avpA-5xk2A:
undetectable
3avpA-5xk2A:
15.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5xmb PANTOTHENATE KINASE

(Mycobacterium
tuberculosis)
no annotation 7 VAL A  99
ASP A 129
HIS A 179
LEU A 203
TYR A 235
ILE A 272
ASN A 277
SO4  A 401 ( 4.2A)
None
None
None
None
None
None
0.76A 3avpA-5xmbA:
37.7
3avpA-5xmbA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xu1 ABC TRANSPORTER
ATP-BINDING PROTEIN


(Streptococcus
pneumoniae)
no annotation 4 VAL A  31
ASP A 224
LEU A  29
ILE A 197
None
0.93A 3avpA-5xu1A:
undetectable
3avpA-5xu1A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xu1 ABC TRANSPORTER
PERMEAE


(Streptococcus
pneumoniae)
no annotation 4 ASP M  49
TYR M 201
ILE M 219
ASN M 146
None
0.98A 3avpA-5xu1M:
undetectable
3avpA-5xu1M:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1


(Mus musculus)
no annotation 4 VAL A 320
ASP A 235
LEU A 316
ILE A 226
None
0.99A 3avpA-6c96A:
undetectable
3avpA-6c96A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cg7 CADHERIN-22

(Mus musculus)
no annotation 4 VAL A  96
ASP A 101
TYR A  71
ILE A  47
None
CA  A 301 ( 2.7A)
None
None
0.91A 3avpA-6cg7A:
undetectable
3avpA-6cg7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cgb CADHERIN-11,
CADHERIN-6 CHIMERA


(Mus musculus)
no annotation 4 VAL A  96
ASP A 101
TYR A  71
ILE A  47
None
CA  A 302 (-2.9A)
None
None
1.03A 3avpA-6cgbA:
undetectable
3avpA-6cgbA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6es9 ACYL-COA
DEHYDROGENASE


(Paracoccus
denitrificans)
no annotation 4 HIS A 321
LEU A 208
TYR A 243
ILE A 244
None
0.99A 3avpA-6es9A:
undetectable
3avpA-6es9A:
12.82