SIMILAR PATTERNS OF AMINO ACIDS FOR 3AVP_A_MV2A313
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a9x | CARBAMOYL PHOSPHATESYNTHETASE (SMALLCHAIN) (Escherichiacoli) |
PF00117(GATase)PF00988(CPSase_sm_chain) | 4 | VAL B1530ASP B1511LEU B1622ILE B1610 | None | 0.92A | 3avpA-1a9xB:undetectable | 3avpA-1a9xB:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b1y | PROTEIN(BETA-AMYLASE) (Hordeum vulgare) |
PF01373(Glyco_hydro_14) | 4 | VAL A 361ASP A 346ILE A 392ASN A 395 | None | 1.02A | 3avpA-1b1yA:0.0 | 3avpA-1b1yA:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1btc | BETA-AMYLASE (Glycine max) |
PF01373(Glyco_hydro_14) | 4 | VAL A 363ASP A 348ILE A 394ASN A 397 | BME A 504 (-4.5A)NoneNoneNone | 0.97A | 3avpA-1btcA:0.0 | 3avpA-1btcA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1exb | KV BETA2 PROTEIN (Rattusnorvegicus) |
PF00248(Aldo_ket_red) | 4 | VAL A 114LEU A 47ILE A 81ASN A 82 | None | 1.02A | 3avpA-1exbA:0.0 | 3avpA-1exbA:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gq7 | PROCLAVAMINATEAMIDINO HYDROLASE (Streptomycesclavuligerus) |
PF00491(Arginase) | 4 | VAL A 140ASP A 276HIS A 121ILE A 168 | NoneNone MN A 350 (-3.3A)None | 0.99A | 3avpA-1gq7A:0.0 | 3avpA-1gq7A:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1htq | GLUTAMINE SYNTHETASE (Mycobacteriumtuberculosis) |
PF00120(Gln-synt_C)PF03951(Gln-synt_N) | 4 | ASP A 70HIS A 230ILE A 116ASN A 113 | None | 1.02A | 3avpA-1htqA:undetectable | 3avpA-1htqA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kon | PROTEIN YEBC (Escherichiacoli) |
PF01709(Transcrip_reg) | 4 | VAL A 163ASP A 167TYR A 173ILE A 201 | None | 1.01A | 3avpA-1konA:0.0 | 3avpA-1konA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nrw | HYPOTHETICALPROTEIN, HALOACIDDEHALOGENASE-LIKEHYDROLASE (Bacillussubtilis) |
PF08282(Hydrolase_3) | 4 | VAL A 48ASP A 9HIS A 17ILE A 57 | NonePO4 A 900 ( 3.6A)NoneNone | 1.04A | 3avpA-1nrwA:0.0 | 3avpA-1nrwA:20.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1sq5 | PANTOTHENATE KINASE (Escherichiacoli) |
PF00485(PRK) | 5 | VAL A1097ASP A1127HIS A1177LEU A1201ASN A1282 | ADP A5001 ( 4.4A)PAU A6001 (-2.9A)PAU A6001 (-4.2A)NonePAU A6001 (-3.0A) | 1.00A | 3avpA-1sq5A:37.1 | 3avpA-1sq5A:52.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1sq5 | PANTOTHENATE KINASE (Escherichiacoli) |
PF00485(PRK) | 5 | VAL A1097ASP A1127LEU A1201TYR A1240ASN A1282 | ADP A5001 ( 4.4A)PAU A6001 (-2.9A)NonePAU A6001 (-4.3A)PAU A6001 (-3.0A) | 0.92A | 3avpA-1sq5A:37.1 | 3avpA-1sq5A:52.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yni | SUCCINYLARGININEDIHYDROLASE (Escherichiacoli) |
PF04996(AstB) | 4 | VAL A 195LEU A 193ILE A 252ASN A 249 | None | 0.81A | 3avpA-1yniA:undetectable | 3avpA-1yniA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yq9 | PERIPLASMIC [NIFE]HYDROGENASE SMALLSUBUNIT (Desulfovibriogigas) |
PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 4 | VAL A 24HIS A 13LEU A 25ILE A 40 | None | 1.04A | 3avpA-1yq9A:undetectable | 3avpA-1yq9A:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z2o | INOSITOL1,3,4-TRISPHOSPHATE5/6-KINASE (Entamoebahistolytica) |
PF05770(Ins134_P3_kin) | 4 | HIS X 88LEU X 13TYR X 296ILE X 183 | None | 0.98A | 3avpA-1z2oX:undetectable | 3avpA-1z2oX:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a62 | CADHERIN-8 (Mus musculus) |
PF00028(Cadherin) | 4 | VAL A 96ASP A 101TYR A 71ILE A 47 | None CA A 325 ( 2.7A)NoneNone | 1.00A | 3avpA-2a62A:undetectable | 3avpA-2a62A:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b0t | NADP ISOCITRATEDEHYDROGENASE (Corynebacteriumglutamicum) |
PF03971(IDH) | 4 | VAL A 127ASP A 10TYR A 124ILE A 105 | None | 0.92A | 3avpA-2b0tA:3.2 | 3avpA-2b0tA:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c1i | PEPTIDOGLYCAN GLCNACDEACETYLASE (Streptococcuspneumoniae) |
PF01522(Polysacc_deac_1) | 4 | ASP A 276HIS A 330LEU A 415ILE A 370 | ZN A1465 ( 2.3A) ZN A1465 ( 3.2A)NoneNone | 0.97A | 3avpA-2c1iA:undetectable | 3avpA-2c1iA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dlt | MYOSIN BINDINGPROTEIN C, FAST-TYPE (Mus musculus) |
PF07679(I-set) | 4 | VAL A 32HIS A 58LEU A 9ILE A 15 | None | 0.91A | 3avpA-2dltA:undetectable | 3avpA-2dltA:15.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eq9 | PYRUVATEDEHYDROGENASECOMPLEX,DIHYDROLIPOAMIDEDEHYDROGENASE E3COMPONENT (Thermusthermophilus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | VAL A 400ASP A 407HIS A 461LEU A 409 | None | 0.98A | 3avpA-2eq9A:undetectable | 3avpA-2eq9A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fff | PENICILLIN-BINDINGPROTEIN 1B (Streptococcuspneumoniae) |
PF00905(Transpeptidase) | 4 | HIS B 567LEU B 620TYR B 608ILE B 470 | None | 0.97A | 3avpA-2fffB:undetectable | 3avpA-2fffB:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fjl | 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATEPHOSPHODIESTERASEGAMMA 1 (Rattusnorvegicus) |
PF00169(PH) | 4 | VAL A 23ASP A 80TYR A 21ASN A 4 | None | 1.01A | 3avpA-2fjlA:undetectable | 3avpA-2fjlA:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2glj | PROBABLE M18-FAMILYAMINOPEPTIDASE 1 (Clostridiumacetobutylicum) |
PF02127(Peptidase_M18) | 4 | ASP A 342HIS A 105LEU A 437TYR A 262 | MN A6002 (-2.0A) MN A6002 (-3.4A)NoneNone | 1.03A | 3avpA-2gljA:undetectable | 3avpA-2gljA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iw0 | CHITIN DEACETYLASE (Colletotrichumlindemuthianum) |
PF01522(Polysacc_deac_1) | 4 | ASP A 50HIS A 108LEU A 204ILE A 163 | ZN A1255 ( 2.5A) ZN A1255 ( 3.2A)NoneNone | 0.88A | 3avpA-2iw0A:undetectable | 3avpA-2iw0A:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j7m | HYALURONIDASE (Clostridiumperfringens) |
PF00754(F5_F8_type_C) | 4 | VAL A 763LEU A 674TYR A 687ILE A 698 | None | 1.00A | 3avpA-2j7mA:undetectable | 3avpA-2j7mA:17.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jb1 | L-AMINO ACID OXIDASE (Rhodococcusopacus) |
PF01593(Amino_oxidase) | 4 | VAL A 261LEU A 301TYR A 275ILE A 284 | FAD A1489 (-3.7A)NoneNoneNone | 1.04A | 3avpA-2jb1A:undetectable | 3avpA-2jb1A:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jch | PENICILLIN-BINDINGPROTEIN 1B (Streptococcuspneumoniae) |
PF00905(Transpeptidase)PF00912(Transgly) | 4 | HIS A 567LEU A 620TYR A 608ILE A 470 | None | 1.02A | 3avpA-2jchA:undetectable | 3avpA-2jchA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ly2 | TUDORDOMAIN-CONTAININGPROTEIN 7 (Mus musculus) |
PF12872(OST-HTH) | 4 | VAL A 295HIS A -1LEU A 291ILE A 305 | None | 0.83A | 3avpA-2ly2A:undetectable | 3avpA-2ly2A:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nrj | HBL B PROTEIN (Bacillus cereus) |
PF05791(Bacillus_HBL) | 4 | VAL A 254ASP A 181ILE A 220ASN A 46 | None | 1.05A | 3avpA-2nrjA:undetectable | 3avpA-2nrjA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2odl | ADHESIN (Haemophilusinfluenzae) |
PF05860(Haemagg_act) | 4 | VAL A 146LEU A 140ILE A 100ASN A 126 | None | 1.05A | 3avpA-2odlA:undetectable | 3avpA-2odlA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2quq | CENTROMEREDNA-BINDING PROTEINCOMPLEX CBF3 SUBUNITB (Saccharomycescerevisiae) |
PF16846(Cep3) | 4 | VAL A 477ASP A 423LEU A 58ILE A 470 | None | 0.96A | 3avpA-2quqA:undetectable | 3avpA-2quqA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rb5 | PUTATIVEUNCHARACTERIZEDPROTEIN (Bacteroidesthetaiotaomicron) |
PF08282(Hydrolase_3) | 4 | VAL A 14ASP A 211ILE A 50ASN A 52 | None MG A 701 (-2.5A)NoneNone | 0.95A | 3avpA-2rb5A:undetectable | 3avpA-2rb5A:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v5d | O-GLCNACASE NAGJ (Clostridiumperfringens) |
PF00754(F5_F8_type_C)PF02838(Glyco_hydro_20b)PF07555(NAGidase) | 4 | VAL A 763LEU A 674TYR A 687ILE A 698 | None | 0.93A | 3avpA-2v5dA:undetectable | 3avpA-2v5dA:17.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vrc | TRIPHENYLMETHANEREDUCTASE (Citrobacter sp.MY-5) |
PF05368(NmrA) | 4 | HIS A 19LEU A 267TYR A 143ASN A 140 | None | 1.02A | 3avpA-2vrcA:undetectable | 3avpA-2vrcA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xvr | MAJOR CAPSID PROTEIN10A (Escherichiavirus T7) |
no annotation | 4 | VAL A 298LEU A 303ILE A 239ASN A 241 | None | 0.92A | 3avpA-2xvrA:undetectable | 3avpA-2xvrA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zbm | PROTEIN-TYROSINE-PHOSPHATASE (Shewanella sp.) |
PF00149(Metallophos) | 4 | VAL A 154ASP A 114HIS A 80TYR A 177 | None ZN A 402 ( 2.8A) ZN A 401 (-3.2A)None | 1.00A | 3avpA-2zbmA:undetectable | 3avpA-2zbmA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3av3 | PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASE (Geobacilluskaustophilus) |
PF00551(Formyl_trans_N) | 4 | VAL A 35LEU A 33TYR A 89ILE A 93 | None | 1.01A | 3avpA-3av3A:undetectable | 3avpA-3av3A:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ay3 | NAD-DEPENDENTEPIMERASE/DEHYDRATASE (Chromohalobactersalexigens) |
PF01370(Epimerase) | 4 | VAL A 201ASP A 144TYR A 203ILE A 123 | None | 0.96A | 3avpA-3ay3A:undetectable | 3avpA-3ay3A:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b8l | UNCHARACTERIZEDPROTEIN (Novosphingobiumaromaticivorans) |
PF13577(SnoaL_4) | 4 | VAL A 94ASP A 23LEU A 75ILE A 46 | None | 0.91A | 3avpA-3b8lA:undetectable | 3avpA-3b8lA:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bjx | HALOCARBOXYLIC ACIDDEHALOGENASE DEHI (Pseudomonasputida) |
PF10778(DehI) | 4 | VAL A 103ASP A 284LEU A 107ILE A 202 | None | 0.91A | 3avpA-3bjxA:undetectable | 3avpA-3bjxA:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cdx | SUCCINYLGLUTAMATEDESUCCINYLASE/ASPARTOACYLASE (Rhodobactersphaeroides) |
PF04952(AstE_AspA) | 4 | ASP A 146HIS A 148LEU A 133ILE A 99 | None CA A 401 (-3.3A)NoneNone | 0.98A | 3avpA-3cdxA:undetectable | 3avpA-3cdxA:23.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fmc | PUTATIVESUCCINYLGLUTAMATEDESUCCINYLASE /ASPARTOACYLASE (Shewanellaamazonensis) |
PF04952(AstE_AspA) | 4 | ASP A 169HIS A 171LEU A 157ILE A 79 | None | 0.84A | 3avpA-3fmcA:undetectable | 3avpA-3fmcA:22.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gb4 | DDMC (Stenotrophomonasmaltophilia) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A) | 4 | ASP A 294HIS A 165LEU A 155ASN A 230 | CO A 502 (-1.9A) CO A 502 (-3.3A)NoneD3M A 601 (-2.8A) | 1.00A | 3avpA-3gb4A:undetectable | 3avpA-3gb4A:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iv3 | TAGATOSE1,6-DIPHOSPHATEALDOLASE 2 (Streptococcusmutans) |
PF01791(DeoC) | 4 | VAL A 213LEU A 256TYR A 214ASN A 211 | NoneNoneNoneEDO A 334 (-3.5A) | 0.98A | 3avpA-3iv3A:undetectable | 3avpA-3iv3A:23.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k5s | CADHERIN-13 (Gallus gallus) |
PF00028(Cadherin) | 4 | VAL A 97ASP A 102TYR A 73ILE A 49 | VAL A 97 ( 0.6A)ASP A 102 ( 0.6A)TYR A 73 ( 1.3A)ILE A 49 ( 0.6A) | 0.79A | 3avpA-3k5sA:undetectable | 3avpA-3k5sA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kq4 | GASTRIC INTRINSICFACTOR (Homo sapiens) |
PF01122(Cobalamin_bind)PF14478(DUF4430) | 4 | VAL A 346LEU A 347ILE A 333ASN A 334 | None | 1.03A | 3avpA-3kq4A:undetectable | 3avpA-3kq4A:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l5o | UNCHARACTERIZEDPROTEIN FROM DUF364FAMILY (Desulfitobacteriumhafniense) |
PF04016(DUF364)PF13938(DUF4213) | 4 | VAL A 128ASP A 180LEU A 158ILE A 196 | NoneIMD A 303 ( 2.8A)IMD A 303 (-4.2A)None | 0.98A | 3avpA-3l5oA:undetectable | 3avpA-3l5oA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lu2 | LMO2462 PROTEIN (Listeriamonocytogenes) |
PF01244(Peptidase_M19) | 4 | ASP A 9HIS A 7ILE A 142ASN A 133 | ZN A 310 (-2.7A) ZN A 310 (-4.5A)NoneNone | 1.04A | 3avpA-3lu2A:undetectable | 3avpA-3lu2A:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lwu | SUCCINYLGLUTAMATEDESUCCINYLASE/ASPARTOACYLASE (Shewanellafrigidimarina) |
PF04952(AstE_AspA) | 4 | ASP A 171HIS A 173LEU A 159ILE A 81 | None ZN A 374 (-3.1A)NoneNone | 0.91A | 3avpA-3lwuA:undetectable | 3avpA-3lwuA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nwu | SERINE PROTEASEHTRA1 (Homo sapiens) |
PF13365(Trypsin_2) | 4 | VAL A 221HIS A 185ILE A 342ASN A 218 | NoneNoneNoneSO4 A 1 (-3.0A) | 1.06A | 3avpA-3nwuA:undetectable | 3avpA-3nwuA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ppe | VASCULAR ENDOTHELIALCADHERIN (Gallus gallus) |
PF00028(Cadherin) | 4 | VAL A 94ASP A 99TYR A 69ILE A 45 | None CA A 401 ( 2.6A)NoneNone | 0.88A | 3avpA-3ppeA:undetectable | 3avpA-3ppeA:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ros | NAD-DEPENDENTALDEHYDEDEHYDROGENASE (Lactobacillusacidophilus) |
PF00171(Aldedh) | 4 | VAL A 148LEU A 443ILE A 125ASN A 145 | None | 1.04A | 3avpA-3rosA:undetectable | 3avpA-3rosA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s25 | HYPOTHETICAL7-BLADEDBETA-PROPELLER-LIKEPROTEIN ([Eubacterium]rectale) |
PF16472(DUF5050) | 4 | VAL A 35ASP A 53ILE A 164ASN A 31 | EDO A 332 (-4.5A)EDO A 332 (-2.9A)NoneNone | 1.04A | 3avpA-3s25A:undetectable | 3avpA-3s25A:17.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sim | PROTEIN, FAMILY 18CHITINASE (Crocus vernus) |
PF00704(Glyco_hydro_18) | 4 | VAL A 4LEU A 2TYR A 6ASN A 184 | None | 0.87A | 3avpA-3simA:undetectable | 3avpA-3simA:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sub | ADP-RIBOSYLATIONFACTORGTPASE-ACTIVATINGPROTEIN (Plasmodiumfalciparum) |
PF01412(ArfGap) | 4 | ASP A 24HIS A 49LEU A 87ILE A 135 | None | 0.87A | 3avpA-3subA:undetectable | 3avpA-3subA:20.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3tqc | PANTOTHENATE KINASE (Coxiellaburnetii) |
PF00485(PRK) | 4 | VAL A 98ASP A 128HIS A 178LEU A 202 | ADP A 500 ( 4.4A)NoneNoneNone | 0.89A | 3avpA-3tqcA:37.3 | 3avpA-3tqcA:51.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3tqc | PANTOTHENATE KINASE (Coxiellaburnetii) |
PF00485(PRK) | 4 | VAL A 98HIS A 178LEU A 202ASN A 283 | ADP A 500 ( 4.4A)NoneNoneNone | 0.69A | 3avpA-3tqcA:37.3 | 3avpA-3tqcA:51.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3tqc | PANTOTHENATE KINASE (Coxiellaburnetii) |
PF00485(PRK) | 4 | VAL A 98LEU A 202TYR A 241ASN A 283 | ADP A 500 ( 4.4A)NoneNoneNone | 0.37A | 3avpA-3tqcA:37.3 | 3avpA-3tqcA:51.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zg6 | NAD-DEPENDENTPROTEIN DEACETYLASESIRTUIN-6 (Homo sapiens) |
PF02146(SIR2) | 4 | VAL A 259HIS A 266LEU A 28ILE A 209 | None | 1.00A | 3avpA-3zg6A:undetectable | 3avpA-3zg6A:23.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a5o | BIFUNCTIONAL PROTEINFOLD (Pseudomonasaeruginosa) |
PF00763(THF_DHG_CYH)PF02882(THF_DHG_CYH_C) | 4 | VAL A 171ASP A 121ILE A 232ASN A 169 | None | 1.04A | 3avpA-4a5oA:2.7 | 3avpA-4a5oA:26.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c23 | L-FUCULOSE KINASEFUCK (Streptococcuspneumoniae) |
PF00370(FGGY_N)PF02782(FGGY_C) | 4 | VAL A 370LEU A 348TYR A 371ILE A 317 | None | 0.94A | 3avpA-4c23A:undetectable | 3avpA-4c23A:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dq6 | PUTATIVE PYRIDOXALPHOSPHATE-DEPENDENTTRANSFERASE (Clostridioidesdifficile) |
PF00155(Aminotran_1_2) | 4 | ASP A 259TYR A 69ILE A 73ASN A 70 | None | 1.06A | 3avpA-4dq6A:undetectable | 3avpA-4dq6A:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ep0 | MAJOR TAIL PROTEIN (Streptococcusvirus C1) |
PF16838(Caud_tail_N) | 4 | VAL A 553ASP A 110LEU A 548ILE A 517 | None | 1.05A | 3avpA-4ep0A:undetectable | 3avpA-4ep0A:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdy | SIMILAR TOLIPOPROTEIN, NLP/P60FAMILY (Staphylococcusaureus) |
PF00877(NLPC_P60)PF13702(Lysozyme_like) | 4 | VAL A 198ASP A 131TYR A 197ILE A 79 | None | 1.01A | 3avpA-4fdyA:undetectable | 3avpA-4fdyA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g56 | MGC81050 PROTEIN (Xenopus laevis) |
PF00400(WD40) | 4 | VAL B 24HIS B 314LEU B 34ILE B 264 | None | 1.04A | 3avpA-4g56B:undetectable | 3avpA-4g56B:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k0e | HEAVY METAL CATIONTRICOMPONENT EFFLUXPUMP ZNEA(CZCA-LIKE) (Cupriavidusmetallidurans) |
PF00873(ACR_tran) | 4 | ASP A 393LEU A 997ILE A 930ASN A 927 | None | 1.00A | 3avpA-4k0eA:undetectable | 3avpA-4k0eA:15.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kk7 | ESX-1 SECRETIONSYSTEM PROTEIN ECCB1 (Mycobacteriumtuberculosis) |
PF05108(T7SS_ESX1_EccB) | 4 | VAL A 361HIS A 204LEU A 181ILE A 228 | None | 0.98A | 3avpA-4kk7A:undetectable | 3avpA-4kk7A:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l1g | PEPTIDOGLYCANN-ACETYLGLUCOSAMINEDEACETYLASE (Bacillus cereus) |
PF01522(Polysacc_deac_1) | 4 | ASP A 81HIS A 135LEU A 223ILE A 175 | ACT A 302 ( 4.0A)PXU A 171 (-3.6A)NoneNone | 0.98A | 3avpA-4l1gA:undetectable | 3avpA-4l1gA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l1g | PEPTIDOGLYCANN-ACETYLGLUCOSAMINEDEACETYLASE (Bacillus cereus) |
PF01522(Polysacc_deac_1) | 4 | ASP A 81HIS A 135LEU A 223ILE A 190 | ACT A 302 ( 4.0A)PXU A 171 (-3.6A)NoneNone | 0.91A | 3avpA-4l1gA:undetectable | 3avpA-4l1gA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ml1 | DSBP (Klebsiellapneumoniae) |
PF10411(DsbC_N)PF13098(Thioredoxin_2) | 4 | VAL A 198ASP A 66HIS A 72ILE A 185 | None | 1.04A | 3avpA-4ml1A:undetectable | 3avpA-4ml1A:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n7t | PHOSPHOPENTOMUTASE (Streptococcusmutans) |
PF01676(Metalloenzyme) | 4 | VAL A 70ASP A 318LEU A 48ILE A 61 | None | 1.05A | 3avpA-4n7tA:undetectable | 3avpA-4n7tA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nhy | 2-OXOGLUTARATE ANDIRON-DEPENDENTOXYGENASEDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF10637(Ofd1_CTDD)PF13661(2OG-FeII_Oxy_4) | 4 | VAL A 197ASP A 57HIS A 63ILE A 187 | None | 0.96A | 3avpA-4nhyA:undetectable | 3avpA-4nhyA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oh1 | L-IDITOL2-DEHYDROGENASE ([Clostridium]scindens) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | VAL A 160HIS A 73LEU A 184ILE A 298 | None ZN A 401 (-3.5A)NoneNone | 0.72A | 3avpA-4oh1A:undetectable | 3avpA-4oh1A:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4om9 | SERINE PROTEASE PET (Escherichiacoli) |
PF02395(Peptidase_S6) | 4 | ASP A 522HIS A 519TYR A 471ILE A 443 | None | 0.63A | 3avpA-4om9A:undetectable | 3avpA-4om9A:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oou | BETA-1,4-MANNANASE (Cryptopygusantarcticus) |
no annotation | 4 | ASP B 233LEU B 237TYR B 32ILE B 381 | None | 0.99A | 3avpA-4oouB:undetectable | 3avpA-4oouB:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oy2 | TRANSCRIPTIONINITIATION FACTORTFIID SUBUNIT 7 (Saccharomycescerevisiae) |
PF04658(TAFII55_N) | 5 | VAL B 292LEU B 296TYR B 288ILE B 227ASN B 230 | None | 1.23A | 3avpA-4oy2B:undetectable | 3avpA-4oy2B:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r0k | DIPEPTIDYL-PEPTIDASEVI (Bacteroidesthetaiotaomicron) |
PF00877(NLPC_P60) | 4 | VAL A 130LEU A 58TYR A 112ILE A 189 | None | 1.03A | 3avpA-4r0kA:undetectable | 3avpA-4r0kA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rk2 | PUTATIVE SUGAR ABCTRANSPORTER,SUBSTRATE-BINDINGPROTEIN (Rhizobium etli) |
PF01547(SBP_bac_1) | 4 | VAL A 203ASP A 176LEU A 196ILE A 402 | None | 1.01A | 3avpA-4rk2A:undetectable | 3avpA-4rk2A:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rt6 | HEME/HEMOPEXIN-BINDING PROTEIN (Haemophilusinfluenzae) |
PF05860(Haemagg_act) | 4 | VAL A 82LEU A 76ILE A 36ASN A 62 | None | 1.05A | 3avpA-4rt6A:undetectable | 3avpA-4rt6A:16.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rxx | UBIQUITINCARBOXYL-TERMINALHYDROLASE 38 (Homo sapiens) |
no annotation | 4 | VAL A 60ASP A 54LEU A 48ILE A 21 | None | 1.05A | 3avpA-4rxxA:undetectable | 3avpA-4rxxA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yub | NICOTINATEPHOSPHORIBOSYLTRANSFERASE (Homo sapiens) |
no annotation | 4 | ASP A 288HIS A 213LEU A 324ILE A 358 | None | 1.02A | 3avpA-4yubA:undetectable | 3avpA-4yubA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ywg | HEAVY CHAIN OFANTI-HIV-1 GP120V1V2 ANTIBODY 830A (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | VAL H 24ASP H 101LEU H 4ILE H 71 | None | 0.89A | 3avpA-4ywgH:undetectable | 3avpA-4ywgH:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b04 | PROBABLE TRANSLATIONINITIATION FACTOREIF-2B SUBUNITEPSILON (Schizosaccharomycespombe) |
PF00132(Hexapep)PF00483(NTP_transferase) | 4 | VAL I 230ASP I 122HIS I 143ILE I 243 | None | 1.00A | 3avpA-5b04I:undetectable | 3avpA-5b04I:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5et1 | ESPINMYOSIN-IIIB (Mus musculus) |
PF12796(Ank_2)PF13637(Ank_4)PF13857(Ank_5)no annotation | 4 | ASP A 33HIS A 42TYR C1268ASN A 69 | None | 0.94A | 3avpA-5et1A:undetectable | 3avpA-5et1A:23.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i08 | SPIKE GLYCOPROTEIN,ENVELOPEGLYCOPROTEIN CHIMERA (HumancoronavirusHKU1;Humanimmunodeficiencyvirus 1) |
PF01601(Corona_S2)PF09408(Spike_rec_bind)PF16451(Spike_NTD) | 4 | VAL A 363ASP A 328LEU A 359ILE A 588 | None | 1.04A | 3avpA-5i08A:undetectable | 3avpA-5i08A:11.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iu9 | PROTOCADHERIN-19ISOFORM 1 (Danio rerio) |
PF00028(Cadherin)PF08266(Cadherin_2) | 4 | VAL A 205ASP A 210TYR A 181ILE A 150 | None CA A1004 ( 2.5A)NoneNone | 0.75A | 3avpA-5iu9A:undetectable | 3avpA-5iu9A:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j4a | IMMUNITY PROTEINCDII (Burkholderiapseudomallei) |
no annotation | 4 | VAL B 42LEU B 59TYR B 43ILE B 27 | None | 0.99A | 3avpA-5j4aB:undetectable | 3avpA-5j4aB:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jjo | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
PF08238(Sel1) | 4 | VAL A 51ASP A 262TYR A 47ASN A 83 | None | 1.01A | 3avpA-5jjoA:undetectable | 3avpA-5jjoA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jvf | SITE-DETERMININGPROTEIN (Pseudomonasaeruginosa) |
PF10609(ParA) | 4 | VAL A 149ASP A 127ILE A 214ASN A 181 | NoneNoneNoneIOD A 311 (-4.3A) | 1.03A | 3avpA-5jvfA:undetectable | 3avpA-5jvfA:24.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l9w | ACETOPHENONECARBOXYLASE DELTASUBUNITACETOPHENONECARBOXYLASE GAMMASUBUNIT (Aromatoleumaromaticum) |
PF01968(Hydantoinase_A)PF02538(Hydantoinase_B)PF05378(Hydant_A_N) | 4 | VAL B 367ASP B 394HIS B 478ILE A 36 | None | 0.91A | 3avpA-5l9wB:undetectable | 3avpA-5l9wB:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lw7 | ABC TRANSPORTERATP-BINDING PROTEIN (Pyrococcusabyssi) |
PF00005(ABC_tran)PF00037(Fer4)PF04068(RLI) | 4 | VAL B 420LEU B 458TYR B 451ILE B 448 | None | 1.05A | 3avpA-5lw7B:1.8 | 3avpA-5lw7B:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o6y | PEPTIDOGLYCANN-ACETYLGLUCOSAMINEDEACETYLASE (Bacillus cereus) |
no annotation | 4 | ASP B 81HIS B 135LEU B 223ILE B 190 | 5YA B 302 ( 2.5A) ZN B 303 ( 3.7A)NoneNone | 0.94A | 3avpA-5o6yB:undetectable | 3avpA-5o6yB:11.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vxl | INVASIN IPADSINGLE-DOMAINANTIBODY JPS-G3 (Shigellaflexneri;Vicugna pacos) |
PF06511(IpaD)no annotation | 4 | VAL A 170LEU A 174TYR B 54ILE B 31 | None | 0.98A | 3avpA-5vxlA:undetectable | 3avpA-5vxlA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xgo | DNA PROTECTIONDURING STARVATIONPROTEIN,BACTERIOFERRITIN (Escherichiacoli) |
no annotation | 4 | VAL A 114ASP A 167LEU A 118ILE A 60 | None | 1.01A | 3avpA-5xgoA:undetectable | 3avpA-5xgoA:12.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xk2 | DIACYLGLYCEROLLIPASE (Aspergillusoryzae) |
no annotation | 4 | VAL A 77ASP A 38TYR A 145ASN A 79 | None | 1.03A | 3avpA-5xk2A:undetectable | 3avpA-5xk2A:15.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5xmb | PANTOTHENATE KINASE (Mycobacteriumtuberculosis) |
no annotation | 7 | VAL A 99ASP A 129HIS A 179LEU A 203TYR A 235ILE A 272ASN A 277 | SO4 A 401 ( 4.2A)NoneNoneNoneNoneNoneNone | 0.76A | 3avpA-5xmbA:37.7 | 3avpA-5xmbA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xu1 | ABC TRANSPORTERATP-BINDING PROTEIN (Streptococcuspneumoniae) |
no annotation | 4 | VAL A 31ASP A 224LEU A 29ILE A 197 | None | 0.93A | 3avpA-5xu1A:undetectable | 3avpA-5xu1A:16.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xu1 | ABC TRANSPORTERPERMEAE (Streptococcuspneumoniae) |
no annotation | 4 | ASP M 49TYR M 201ILE M 219ASN M 146 | None | 0.98A | 3avpA-5xu1M:undetectable | 3avpA-5xu1M:13.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c96 | TWO PORE CALCIUMCHANNEL PROTEIN 1 (Mus musculus) |
no annotation | 4 | VAL A 320ASP A 235LEU A 316ILE A 226 | None | 0.99A | 3avpA-6c96A:undetectable | 3avpA-6c96A:14.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cg7 | CADHERIN-22 (Mus musculus) |
no annotation | 4 | VAL A 96ASP A 101TYR A 71ILE A 47 | None CA A 301 ( 2.7A)NoneNone | 0.91A | 3avpA-6cg7A:undetectable | 3avpA-6cg7A:15.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cgb | CADHERIN-11,CADHERIN-6 CHIMERA (Mus musculus) |
no annotation | 4 | VAL A 96ASP A 101TYR A 71ILE A 47 | None CA A 302 (-2.9A)NoneNone | 1.03A | 3avpA-6cgbA:undetectable | 3avpA-6cgbA:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6es9 | ACYL-COADEHYDROGENASE (Paracoccusdenitrificans) |
no annotation | 4 | HIS A 321LEU A 208TYR A 243ILE A 244 | None | 0.99A | 3avpA-6es9A:undetectable | 3avpA-6es9A:12.82 |