SIMILAR PATTERNS OF AMINO ACIDS FOR 3ATT_A_ACTA1209

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)

Filter list by:

	Hit	Macromolecule/ Organism	Pfam	Res.	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1jc9	TECHYLECTIN-5A (Tachypleus tridentatus)	PF00147 (Fibrinogen_C)	4	ASP A 151 ARG A 153 ASP A 147 GLU A 149	None	1.35A	3attA-1jc9A: 0.0	3attA-1jc9A: 18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2cvl	PROTEIN TRANSLATION INITIATION INHIBITOR (Thermus thermophilus)	PF01042 (Ribonuc_L-PSP)	4	ASP A 82 ARG A 114 ASP A 79 GLU A 81	None	0.71A	3attA-2cvlA: 0.0	3attA-2cvlA: 17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2jf7	STRICTOSIDINE-O-BETA -D-GLUCOSIDASE (Rauvolfia serpentina)	PF00232 (Glyco_hydro_1)	4	ASP A 183 ARG A 128 ASP A 182 GLU A 186	None	1.35A	3attA-2jf7A: 0.0	3attA-2jf7A: 19.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3att	PUTATIVE UNCHARACTERIZED PROTEIN (Mycobacterium tuberculosis)	PF01636 (APH)	4	ASP A 249 ARG A 251 ASP A 267 GLU A 269	ACT A1209 (-3.3A) ATP A 510 ( 4.9A) MG A 1 (-2.1A) MG A 1 ( 3.0A)	0.03A	3attA-3attA: 59.2	3attA-3attA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3vvw	CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 (Homo sapiens)	PF07888 (CALCOCO1)	4	ASP A 111 ARG A 117 ASP A 54 GLU A 112	None	1.02A	3attA-3vvwA: 0.0	3attA-3vvwA: 15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4a5q	CHI1 (Yersinia entomophaga)	PF00704 (Glyco_hydro_18)	4	ASP A 64 ARG A 108 ASP A 65 GLU A 63	None	1.24A	3attA-4a5qA: 0.0	3attA-4a5qA: 21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4r0k	DIPEPTIDYL-PEPTIDASE VI (Bacteroides thetaiotaomicron)	PF00877 (NLPC_P60)	4	ASP A 289 ARG A 272 ASP A 286 GLU A 288	None	1.28A	3attA-4r0kA: 0.0	3attA-4r0kA: 21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5guw	NITRIC OXIDE REDUCTASE SUBUNIT C (Pseudomonas aeruginosa)	PF00034 (Cytochrom_C)	4	ASP A 124 ARG A 51 ASP A 123 GLU A 127	None	1.31A	3attA-5guwA: undetectable	3attA-5guwA: 17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5i10	PROBABLE O-METHYLTRANSFERASE (Saccharopolyspora spinosa)	PF05711 (TylF)	4	ASP A 212 ARG A 59 ASP A 185 GLU A 81	MG A 301 (-3.4A) None MG A 301 (-3.5A) None	1.30A	3attA-5i10A: 0.3	3attA-5i10A: 22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5jqe	SUGAR ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN,CASPASE-8 CHIMERA (Escherichia coli)	PF01335 (DED) PF13416 (SBP_bac_8)	4	ASP A1018 ARG A1071 ASP A1015 GLU A1017	None	1.41A	3attA-5jqeA: 0.2	3attA-5jqeA: 22.40

[["3ATT_A_ACTA1209_0","1jc9","Tachypleus tridentatus","TECHYLECTIN-5A","PF00147(Fibrinogen_C)",4,"ASP A 151;ARG A 153;ASP A 147;GLU A 149","None","1.35A","3attA-1jc9A:0.0","3attA-1jc9A:18.85"],["3ATT_A_ACTA1209_0","2cvl","Thermus thermophilus","PROTEIN TRANSLATION INITIATION INHIBITOR","PF01042(Ribonuc_L-PSP)",4,"ASP A  82;ARG A 114;ASP A  79;GLU A  81","None","0.71A","3attA-2cvlA:0.0","3attA-2cvlA:17.32"],["3ATT_A_ACTA1209_0","2jf7","Rauvolfia serpentina","STRICTOSIDINE-O-BETA-D-GLUCOSIDASE","PF00232(Glyco_hydro_1)",4,"ASP A 183;ARG A 128;ASP A 182;GLU A 186","None","1.35A","3attA-2jf7A:0.0","3attA-2jf7A:19.29"],["3ATT_A_ACTA1209_0","3att","Mycobacterium tuberculosis","PUTATIVE UNCHARACTERIZED PROTEIN","PF01636(APH)",4,"ASP A 249;ARG A 251;ASP A 267;GLU A 269","ACT A1209 (-3.3A);ATP A 510 ( 4.9A); MG A   1 (-2.1A); MG A   1 ( 3.0A)","0.03A","3attA-3attA:59.2","3attA-3attA:100.00"],["3ATT_A_ACTA1209_0","3vvw","Homo sapiens","CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2","PF07888(CALCOCO1)",4,"ASP A 111;ARG A 117;ASP A  54;GLU A 112","None","1.02A","3attA-3vvwA:0.0","3attA-3vvwA:15.21"],["3ATT_A_ACTA1209_0","4a5q","Yersinia entomophaga","CHI1","PF00704(Glyco_hydro_18)",4,"ASP A  64;ARG A 108;ASP A  65;GLU A  63","None","1.24A","3attA-4a5qA:0.0","3attA-4a5qA:21.57"],["3ATT_A_ACTA1209_0","4r0k","Bacteroides thetaiotaomicron","DIPEPTIDYL-PEPTIDASE VI","PF00877(NLPC_P60)",4,"ASP A 289;ARG A 272;ASP A 286;GLU A 288","None","1.28A","3attA-4r0kA:0.0","3attA-4r0kA:21.56"],["3ATT_A_ACTA1209_0","5guw","Pseudomonas aeruginosa","NITRIC OXIDE REDUCTASE SUBUNIT C","PF00034(Cytochrom_C)",4,"ASP A 124;ARG A  51;ASP A 123;GLU A 127","None","1.31A","3attA-5guwA:undetectable","3attA-5guwA:17.32"],["3ATT_A_ACTA1209_0","5i10","Saccharopolyspora spinosa","PROBABLE O-METHYLTRANSFERASE","PF05711(TylF)",4,"ASP A 212;ARG A  59;ASP A 185;GLU A  81"," MG A 301 (-3.4A);None; MG A 301 (-3.5A);None","1.30A","3attA-5i10A:0.3","3attA-5i10A:22.28"],["3ATT_A_ACTA1209_0","5jqe","Escherichia coli","SUGAR ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN,CASPASE-8 CHIMERA","PF01335(DED);PF13416(SBP_bac_8)",4,"ASP A1018;ARG A1071;ASP A1015;GLU A1017","None","1.41A","3attA-5jqeA:0.2","3attA-5jqeA:22.40"]]