SIMILAR PATTERNS OF AMINO ACIDS FOR 3AQI_B_CHDB6_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbq FERROCHELATASE

(Saccharomyces
cerevisiae)
PF00762
(Ferrochelatase)
6 ILE A 313
SER A 169
PRO A 238
VAL A 241
VAL A 277
TRP A 282
None
1.37A 3aqiB-1lbqA:
48.3
3aqiB-1lbqA:
49.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbq FERROCHELATASE

(Saccharomyces
cerevisiae)
PF00762
(Ferrochelatase)
9 LEU A  62
PHE A  63
ILE A  91
SER A 169
HIS A 235
PRO A 238
VAL A 241
VAL A 277
TRP A 282
None
0.67A 3aqiB-1lbqA:
48.3
3aqiB-1lbqA:
49.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbq FERROCHELATASE

(Saccharomyces
cerevisiae)
PF00762
(Ferrochelatase)
5 MET A  46
HIS A 235
PRO A 238
VAL A 241
TRP A 282
None
1.06A 3aqiB-1lbqA:
48.3
3aqiB-1lbqA:
49.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qi7 PROTEIN
(N-GLYCOSIDASE)


(Saponaria
officinalis)
PF00161
(RIP)
5 LEU A  64
PHE A  55
ILE A 169
VAL A  27
VAL A 177
None
1.17A 3aqiB-1qi7A:
undetectable
3aqiB-1qi7A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ser PROTEIN (SERYL-TRNA
SYNTHETASE
(E.C.6.1.1.11))


(Thermus
thermophilus)
PF00587
(tRNA-synt_2b)
PF02403
(Seryl_tRNA_N)
5 MET A 140
LEU A 161
LEU A 388
ILE A 150
VAL A 272
None
1.20A 3aqiB-1serA:
undetectable
3aqiB-1serA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vpv UPF0230 PROTEIN
TM1468


(Thermotoga
maritima)
PF02645
(DegV)
5 LEU A 250
PHE A 279
LEU A 230
ILE A 213
SER A 228
None
1.28A 3aqiB-1vpvA:
2.0
3aqiB-1vpvA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wa5 IMPORTIN ALPHA
RE-EXPORTER


(Saccharomyces
cerevisiae)
PF03378
(CAS_CSE1)
PF03810
(IBN_N)
PF08506
(Cse1)
5 LEU C  41
PHE C  61
LEU C  38
ILE C 109
PRO C  79
None
1.21A 3aqiB-1wa5C:
undetectable
3aqiB-1wa5C:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wn1 DIPEPTIDASE

(Pyrococcus
horikoshii)
PF00557
(Peptidase_M24)
PF01321
(Creatinase_N)
5 LEU A  82
LEU A  41
ILE A  91
PRO A  22
VAL A  37
None
1.19A 3aqiB-1wn1A:
undetectable
3aqiB-1wn1A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wom SIGMA FACTOR SIGB
REGULATION PROTEIN
RSBQ


(Bacillus
subtilis)
PF12697
(Abhydrolase_6)
5 MET A 251
LEU A 176
PHE A 180
ILE A 221
SER A  32
PGO  A 604 (-4.6A)
None
None
None
None
1.29A 3aqiB-1womA:
0.0
3aqiB-1womA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yir NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE 2


(Pseudomonas
aeruginosa)
PF04095
(NAPRTase)
5 LEU A  92
PHE A  88
LEU A  78
ILE A 123
PRO A 220
None
1.05A 3aqiB-1yirA:
0.0
3aqiB-1yirA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zag PROTEIN
(ZINC-ALPHA-2-GLYCOP
ROTEIN)


(Homo sapiens)
PF00129
(MHC_I)
PF07654
(C1-set)
5 LEU A  10
LEU A  33
SER A 177
VAL A  57
TRP A  63
None
1.23A 3aqiB-1zagA:
undetectable
3aqiB-1zagA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aeh FOCAL ADHESION
KINASE 1


(Gallus gallus)
PF00373
(FERM_M)
5 LEU A 174
PHE A 231
LEU A 171
PRO A 249
VAL A 250
None
1.29A 3aqiB-2aehA:
undetectable
3aqiB-2aehA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aka DYNAMIN-1

(Rattus
norvegicus)
PF00350
(Dynamin_N)
PF01031
(Dynamin_M)
5 LEU B  48
SER B  45
PRO B  58
VAL B  64
VAL B  97
None
1.26A 3aqiB-2akaB:
undetectable
3aqiB-2akaB:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN


(Torpedo
marmorata)
PF02931
(Neur_chan_LBD)
PF02932
(Neur_chan_memb)
5 LEU A 253
PHE A 225
ILE A 289
PRO A 236
VAL A 295
None
1.32A 3aqiB-2bg9A:
undetectable
3aqiB-2bg9A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dyl DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 7


(Homo sapiens)
PF00069
(Pkinase)
5 LEU A 331
LEU A 235
MET A 238
VAL A 404
VAL A 413
None
1.30A 3aqiB-2dylA:
undetectable
3aqiB-2dylA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e3x COAGULATION FACTOR
X-ACTIVATING ENZYME
HEAVY CHAIN


(Daboia
siamensis)
PF00200
(Disintegrin)
PF01421
(Reprolysin)
PF08516
(ADAM_CR)
5 LEU A 147
MET A 143
ILE A 220
SER A 148
VAL A 168
None
None
CA  A 802 ( 4.7A)
None
None
1.29A 3aqiB-2e3xA:
2.8
3aqiB-2e3xA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e3x COAGULATION FACTOR
X-ACTIVATING ENZYME
HEAVY CHAIN


(Daboia
siamensis)
PF00200
(Disintegrin)
PF01421
(Reprolysin)
PF08516
(ADAM_CR)
5 MET A 119
LEU A 147
MET A 143
ILE A  57
SER A 148
None
1.25A 3aqiB-2e3xA:
2.8
3aqiB-2e3xA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hi4 CYTOCHROME P450 1A2

(Homo sapiens)
PF00067
(p450)
5 LEU A 450
PHE A 451
LEU A 382
ILE A 372
VAL A 227
HEM  A 900 (-4.0A)
HEM  A 900 (-4.1A)
HEM  A 900 (-4.0A)
None
None
1.22A 3aqiB-2hi4A:
undetectable
3aqiB-2hi4A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hmi FAB FRAGMENT OF
MONOCLONAL ANTIBODY
28


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
5 LEU D  69
MET D  85
ILE D  53
PRO D   9
VAL D  12
None
1.20A 3aqiB-2hmiD:
undetectable
3aqiB-2hmiD:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nn3 CASPASE-1

(Spodoptera
frugiperda)
PF00656
(Peptidase_C14)
5 LEU C 236
PHE C 232
LEU C  89
ILE C 283
VAL C 102
None
1.29A 3aqiB-2nn3C:
undetectable
3aqiB-2nn3C:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o8e DNA MISMATCH REPAIR
PROTEIN MSH6


(Homo sapiens)
PF00488
(MutS_V)
PF01624
(MutS_I)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III)
5 LEU B 655
PHE B 643
LEU B 638
ILE B 570
VAL B 688
None
1.20A 3aqiB-2o8eB:
undetectable
3aqiB-2o8eB:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o8e DNA MISMATCH REPAIR
PROTEIN MSH6


(Homo sapiens)
PF00488
(MutS_V)
PF01624
(MutS_I)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III)
5 LEU B1167
LEU B1091
ILE B 788
SER B1094
PRO B1097
None
1.33A 3aqiB-2o8eB:
undetectable
3aqiB-2o8eB:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4i ANGIOPOIETIN-1
RECEPTOR


(Homo sapiens)
PF07714
(Pkinase_Tyr)
5 LEU A 910
LEU A 914
ILE A 980
SER A1033
PRO A1038
None
None
MR9  A 301 (-4.6A)
None
None
1.14A 3aqiB-2p4iA:
undetectable
3aqiB-2p4iA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qgq PROTEIN TM_1862

(Thermotoga
maritima)
PF04055
(Radical_SAM)
5 MET A 241
LEU A 233
ILE A 144
PRO A 254
VAL A 255
None
1.31A 3aqiB-2qgqA:
undetectable
3aqiB-2qgqA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uv8 FATTY ACID SYNTHASE
SUBUNIT BETA (FAS1)


(Saccharomyces
cerevisiae)
PF00698
(Acyl_transf_1)
PF01575
(MaoC_dehydratas)
PF08354
(DUF1729)
PF13452
(MaoC_dehydrat_N)
PF16073
(SAT)
5 LEU G1960
LEU G1904
ILE G1967
SER G1850
VAL G1842
None
1.07A 3aqiB-2uv8G:
undetectable
3aqiB-2uv8G:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w45 ALKALINE EXONUCLEASE

(Human
gammaherpesvirus
4)
PF01771
(Herpes_alk_exo)
5 LEU A  23
ILE A 127
PRO A  39
VAL A  32
VAL A 458
None
1.27A 3aqiB-2w45A:
undetectable
3aqiB-2w45A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x66 PRNB

(Pseudomonas
fluorescens)
PF08933
(DUF1864)
5 LEU A 161
PHE A 171
LEU A 178
VAL A 305
VAL A 354
None
1.28A 3aqiB-2x66A:
undetectable
3aqiB-2x66A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE


(Bifidobacterium
longum)
PF12905
(Glyco_hydro_101)
PF17451
(Glyco_hyd_101C)
5 LEU A 470
ILE A 354
SER A 528
PRO A 592
VAL A 425
None
1.05A 3aqiB-2zxqA:
undetectable
3aqiB-2zxqA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0g HEMOGLOBIN SUBUNIT
ALPHA


(Cavia porcellus)
PF00042
(Globin)
5 LEU A  29
PHE A  33
LEU A 101
ILE A  46
HIS A  87
None
None
HEM  A 201 (-4.1A)
None
HEM  A 201 (-3.3A)
1.23A 3aqiB-3a0gA:
undetectable
3aqiB-3a0gA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3abb CYTOCHROME P450
HYDROXYLASE


(Streptomyces
avermitilis)
PF00067
(p450)
5 LEU A 284
LEU A 363
ILE A 318
PRO A 154
VAL A 153
None
1.30A 3aqiB-3abbA:
undetectable
3aqiB-3abbA:
24.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3aqi FERROCHELATASE

(Homo sapiens)
PF00762
(Ferrochelatase)
12 MET A  76
LEU A  92
PHE A  93
LEU A  98
MET A  99
ILE A 119
SER A 197
HIS A 263
PRO A 266
VAL A 269
VAL A 305
TRP A 310
CHD  A   1 ( 3.8A)
CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
CHD  A   2 (-4.0A)
None
CHD  A   1 (-3.0A)
CHD  A   1 (-4.3A)
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
0.30A 3aqiB-3aqiA:
61.5
3aqiB-3aqiA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bj5 PROTEIN
DISULFIDE-ISOMERASE


(Homo sapiens)
PF13848
(Thioredoxin_6)
5 LEU A 255
ILE A 269
PRO A 296
VAL A 248
VAL A 298
None
1.33A 3aqiB-3bj5A:
undetectable
3aqiB-3bj5A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bvc UNCHARACTERIZED
PROTEIN ISM_01780


(Roseovarius
nubinhibens)
PF13759
(2OG-FeII_Oxy_5)
5 LEU A 105
LEU A  80
ILE A  38
SER A  79
VAL A 132
None
1.24A 3aqiB-3bvcA:
undetectable
3aqiB-3bvcA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cia COLD-ACTIVE
AMINOPEPTIDASE


(Colwellia
psychrerythraea)
PF01433
(Peptidase_M1)
PF09127
(Leuk-A4-hydro_C)
5 LEU A 529
PHE A 525
LEU A 562
SER A 563
VAL A 571
None
1.08A 3aqiB-3ciaA:
undetectable
3aqiB-3ciaA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3do6 FORMATE--TETRAHYDROF
OLATE LIGASE


(Thermotoga
maritima)
PF01268
(FTHFS)
5 LEU A  13
LEU A 279
MET A 275
ILE A   4
SER A 280
None
1.31A 3aqiB-3do6A:
1.5
3aqiB-3do6A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fms TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY


(Thermotoga
maritima)
PF00392
(GntR)
PF07729
(FCD)
5 LEU A 193
LEU A 197
ILE A 101
VAL A 160
TRP A 154
None
1.24A 3aqiB-3fmsA:
undetectable
3aqiB-3fmsA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN


(Ralstonia
solanacearum)
PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
5 LEU A 221
PHE A 222
ILE A 241
HIS A 231
VAL A 128
None
1.34A 3aqiB-3gg9A:
6.0
3aqiB-3gg9A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h6e CARBOHYDRATE KINASE,
FGGY


(Novosphingobium
aromaticivorans)
PF00370
(FGGY_N)
5 LEU A 374
LEU A 408
ILE A 336
SER A 407
VAL A 329
None
1.33A 3aqiB-3h6eA:
undetectable
3aqiB-3h6eA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6s SUBTILISIN-LIKE
PROTEASE


(Solanum
lycopersicum)
PF00082
(Peptidase_S8)
5 LEU A 660
LEU A 494
ILE A 722
SER A 490
PRO A 330
None
1.13A 3aqiB-3i6sA:
undetectable
3aqiB-3i6sA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j8g GTPASE DER

(Escherichia
coli)
PF01926
(MMR_HSR1)
PF14714
(KH_dom-like)
5 LEU X   7
ILE X 143
PRO X   3
VAL X 158
TRP X 162
None
1.27A 3aqiB-3j8gX:
undetectable
3aqiB-3j8gX:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l6a EUKARYOTIC
TRANSLATION
INITIATION FACTOR 4
GAMMA 2


(Homo sapiens)
PF02020
(W2)
PF02847
(MA3)
5 LEU A  89
LEU A 128
ILE A  49
VAL A 162
VAL A 119
None
None
None
MES  A 361 (-3.6A)
None
1.16A 3aqiB-3l6aA:
undetectable
3aqiB-3l6aA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lly AGGLUTININ ALPHA
CHAIN


(Maclura
pomifera)
PF01419
(Jacalin)
5 LEU A  28
LEU A 124
ILE A  12
VAL A  72
VAL A  68
None
0.95A 3aqiB-3llyA:
undetectable
3aqiB-3llyA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN


(Bacillus
anthracis)
PF00797
(Acetyltransf_2)
5 LEU A  60
LEU A  56
ILE A 266
SER A  74
VAL A 201
None
1.17A 3aqiB-3lnbA:
undetectable
3aqiB-3lnbA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1m ORF904

(Sulfolobus
islandicus)
PF09250
(Prim-Pol)
PF13010
(pRN1_helical)
5 LEU A 228
PHE A 162
LEU A 110
PRO A 154
TRP A 246
None
1.09A 3aqiB-3m1mA:
undetectable
3aqiB-3m1mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ojc PUTATIVE
ASPARTATE/GLUTAMATE
RACEMASE


(Yersinia pestis)
PF01177
(Asp_Glu_race)
5 MET A 130
LEU A 186
ILE A 161
VAL A 212
VAL A 205
None
1.22A 3aqiB-3ojcA:
5.0
3aqiB-3ojcA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p8a UNCHARACTERIZED
PROTEIN


(Staphylococcus
aureus)
PF13468
(Glyoxalase_3)
5 LEU A 112
PHE A 212
LEU A 228
MET A 214
VAL A 196
None
1.32A 3aqiB-3p8aA:
undetectable
3aqiB-3p8aA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s2j DIPEPTIDASE

(Streptomyces
coelicolor)
PF01244
(Peptidase_M19)
5 LEU A 354
LEU A 345
ILE A 317
SER A   3
VAL A 296
None
1.22A 3aqiB-3s2jA:
undetectable
3aqiB-3s2jA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sxm TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY


(Thermotoga
maritima)
PF07729
(FCD)
5 LEU A 193
LEU A 197
ILE A 101
VAL A 160
TRP A 154
None
1.28A 3aqiB-3sxmA:
undetectable
3aqiB-3sxmA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v4o MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1


(Homo sapiens)
PF00656
(Peptidase_C14)
5 LEU A 515
PHE A 511
ILE A 550
VAL A 380
VAL A 458
None
1.18A 3aqiB-3v4oA:
undetectable
3aqiB-3v4oA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v4o MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1


(Homo sapiens)
PF00656
(Peptidase_C14)
5 LEU A 515
PHE A 511
LEU A 369
ILE A 550
VAL A 380
None
1.25A 3aqiB-3v4oA:
undetectable
3aqiB-3v4oA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vfd SPASTIN

(Homo sapiens)
PF00004
(AAA)
PF09336
(Vps4_C)
5 LEU A 354
LEU A 378
MET A 484
ILE A 344
VAL A 443
None
1.33A 3aqiB-3vfdA:
undetectable
3aqiB-3vfdA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3woh SIAM

(Streptomyces
sp. A7248)
PF13561
(adh_short_C2)
5 LEU A 119
PHE A 123
LEU A 166
SER A 145
VAL A 240
None
1.27A 3aqiB-3wohA:
2.8
3aqiB-3wohA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyi LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 4


(Homo sapiens)
PF07679
(I-set)
PF13855
(LRR_8)
5 LEU A 104
PHE A  95
LEU A 125
ILE A  87
VAL A 170
None
1.18A 3aqiB-3zyiA:
undetectable
3aqiB-3zyiA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4boo ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA


(Torpedo
marmorata)
PF02931
(Neur_chan_LBD)
PF02932
(Neur_chan_memb)
5 LEU A 253
PHE A 225
ILE A 289
PRO A 236
VAL A 295
None
1.31A 3aqiB-4booA:
undetectable
3aqiB-4booA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bv4 PROTEIN TOLL,
VARIABLE LYMPHOCYTE
RECEPTOR B CHIMERA


(Drosophila
melanogaster;
Eptatretus
burgeri)
PF11921
(DUF3439)
PF13855
(LRR_8)
5 PHE R 193
LEU R 199
MET R 220
ILE R 185
SER R 177
None
1.29A 3aqiB-4bv4R:
undetectable
3aqiB-4bv4R:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cr4 26S PROTEASE SUBUNIT
RPT4


(Saccharomyces
cerevisiae)
PF00004
(AAA)
5 MET L 312
LEU L 337
LEU L 343
ILE L 286
VAL L 196
None
1.33A 3aqiB-4cr4L:
undetectable
3aqiB-4cr4L:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eut SERINE/THREONINE-PRO
TEIN KINASE TBK1


(Homo sapiens)
PF00069
(Pkinase)
5 MET A 263
LEU A 277
LEU A 269
ILE A 284
SER A 268
None
0.99A 3aqiB-4eutA:
undetectable
3aqiB-4eutA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4euu SERINE/THREONINE-PRO
TEIN KINASE TBK1


(Homo sapiens)
PF00069
(Pkinase)
5 MET A 263
LEU A 277
LEU A 269
ILE A 284
SER A 268
None
1.03A 3aqiB-4euuA:
undetectable
3aqiB-4euuA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fod ALK TYROSINE KINASE
RECEPTOR


(Homo sapiens)
PF07714
(Pkinase_Tyr)
5 LEU A1204
LEU A1208
ILE A1268
SER A1324
PRO A1329
None
None
None
GOL  A1502 ( 4.7A)
None
1.30A 3aqiB-4fodA:
undetectable
3aqiB-4fodA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gt6 CELL SURFACE PROTEIN

(Faecalibacterium
prausnitzii)
PF13306
(LRR_5)
5 PHE A 136
LEU A 165
ILE A  97
VAL A 191
VAL A 151
None
None
None
EDO  A 908 (-4.5A)
None
1.27A 3aqiB-4gt6A:
undetectable
3aqiB-4gt6A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hq1 PROBABLE RECEPTOR
PROTEIN KINASE TMK1


(Arabidopsis
thaliana)
PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8)
5 LEU A  84
LEU A  87
ILE A 100
PRO A  52
TRP A  55
None
1.26A 3aqiB-4hq1A:
undetectable
3aqiB-4hq1A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i1p MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1


(Homo sapiens)
PF00656
(Peptidase_C14)
6 LEU A 515
PHE A 511
LEU A 369
ILE A 550
VAL A 380
VAL A 458
None
1.39A 3aqiB-4i1pA:
undetectable
3aqiB-4i1pA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4maf ATP SULFURYLASE

(Glycine max)
PF01747
(ATP-sulfurylase)
PF14306
(PUA_2)
5 LEU A 189
LEU A 363
MET A 354
ILE A 196
PRO A 327
None
1.31A 3aqiB-4mafA:
undetectable
3aqiB-4mafA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mxe N-ACETYLTRANSFERASE
ESCO1


(Homo sapiens)
PF13880
(Acetyltransf_13)
5 LEU A 791
LEU A 709
MET A 669
ILE A 766
VAL A 682
None
1.28A 3aqiB-4mxeA:
undetectable
3aqiB-4mxeA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nky STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE


(Homo sapiens)
PF00067
(p450)
5 MET A  68
LEU A 217
LEU A  40
ILE A 393
SER A  39
None
1.20A 3aqiB-4nkyA:
undetectable
3aqiB-4nkyA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4npk EXTENDED
SYNAPTOTAGMIN-2


(Homo sapiens)
PF00168
(C2)
5 LEU A 458
LEU A 397
ILE A 418
SER A 435
TRP A 488
None
1.16A 3aqiB-4npkA:
undetectable
3aqiB-4npkA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o1s V-TYPE ATP SYNTHASE
ALPHA CHAIN


(Thermoplasma
volcanium)
PF14890
(Intein_splicing)
5 LEU A  97
LEU A 167
ILE A 137
PRO A  11
VAL A  12
None
1.33A 3aqiB-4o1sA:
undetectable
3aqiB-4o1sA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p42 EXTENDED
SYNAPTOTAGMIN-2


(Homo sapiens)
PF00168
(C2)
PF17047
(SMP_LBD)
5 LEU A 430
LEU A 369
ILE A 390
SER A 407
TRP A 460
None
1.12A 3aqiB-4p42A:
undetectable
3aqiB-4p42A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q22 GLYCOSIDE HYDROLASE
FAMILY 18


(Serratia
proteamaculans)
PF00704
(Glyco_hydro_18)
5 LEU A 180
LEU A 177
ILE A  82
PRO A 155
VAL A 205
None
1.24A 3aqiB-4q22A:
undetectable
3aqiB-4q22A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qax 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE


(Staphylococcus
aureus)
PF01676
(Metalloenzyme)
PF06415
(iPGM_N)
5 LEU A 485
LEU A 488
ILE A  69
VAL A 470
VAL A 463
None
1.32A 3aqiB-4qaxA:
undetectable
3aqiB-4qaxA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u7l LEUCINE-RICH REPEATS
AND
IMMUNOGLOBULIN-LIKE
DOMAINS PROTEIN 1


(Homo sapiens)
PF01463
(LRRCT)
PF13855
(LRR_8)
5 LEU A 371
LEU A 392
MET A 389
ILE A 354
TRP A 410
None
1.30A 3aqiB-4u7lA:
undetectable
3aqiB-4u7lA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u7l LEUCINE-RICH REPEATS
AND
IMMUNOGLOBULIN-LIKE
DOMAINS PROTEIN 1


(Homo sapiens)
PF01463
(LRRCT)
PF13855
(LRR_8)
5 LEU A 371
LEU A 392
MET A 389
VAL A 381
TRP A 410
None
1.19A 3aqiB-4u7lA:
undetectable
3aqiB-4u7lA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ypv EST8

(Parvibaculum)
PF07859
(Abhydrolase_3)
5 LEU A 239
LEU A 242
SER A 169
VAL A 155
VAL A 247
None
1.23A 3aqiB-4ypvA:
2.8
3aqiB-4ypvA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z0c TOLL-LIKE RECEPTOR
13


(Mus musculus)
PF00560
(LRR_1)
PF13516
(LRR_6)
PF13855
(LRR_8)
5 LEU A 156
PHE A 147
LEU A 176
ILE A 139
VAL A 166
None
1.26A 3aqiB-4z0cA:
undetectable
3aqiB-4z0cA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z64 SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 1


(Arabidopsis
thaliana)
PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8)
5 LEU C 146
LEU C 170
ILE C 109
SER C 194
VAL C 205
None
1.26A 3aqiB-4z64C:
undetectable
3aqiB-4z64C:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z6k ALCOHOL
DEHYDROGENASE


(Moraxella sp.
TAE123)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
5 LEU A 251
LEU A 257
ILE A 228
VAL A 239
VAL A 194
None
1.27A 3aqiB-4z6kA:
undetectable
3aqiB-4z6kA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zrq TRANSCOBALAMIN-2

(Homo sapiens)
PF01122
(Cobalamin_bind)
PF14478
(DUF4430)
5 LEU A 144
LEU A 183
PRO A 276
VAL A 277
VAL A  38
None
1.29A 3aqiB-4zrqA:
undetectable
3aqiB-4zrqA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxb INSULIN RECEPTOR

(Homo sapiens)
PF00041
(fn3)
PF00757
(Furin-like)
PF01030
(Recep_L_domain)
5 LEU E 385
PHE E 382
LEU E 419
ILE E 336
SER E 446
None
1.12A 3aqiB-4zxbE:
undetectable
3aqiB-4zxbE:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b4x REELIN

(Mus musculus)
PF07974
(EGF_2)
5 PHE A2265
LEU A2261
ILE A2309
PRO A2282
VAL A2227
None
1.31A 3aqiB-5b4xA:
undetectable
3aqiB-5b4xA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cni METABOTROPIC
GLUTAMATE RECEPTOR 2


(Homo sapiens)
PF01094
(ANF_receptor)
5 LEU A  62
PHE A  38
LEU A  26
ILE A 378
VAL A 385
None
1.16A 3aqiB-5cniA:
2.8
3aqiB-5cniA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d3m ENERGY-COUPLING
FACTOR TRANSPORTER
ATP-BINDING PROTEIN
ECFA2


(Lactobacillus
delbrueckii)
PF00005
(ABC_tran)
5 LEU B  26
PHE B  28
LEU B 218
ILE B  64
SER B  44
None
None
None
None
ANP  B 301 (-3.4A)
1.01A 3aqiB-5d3mB:
undetectable
3aqiB-5d3mB:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE


(Bacillus
subtilis)
PF01128
(IspD)
5 LEU A 169
PHE A 164
LEU A  91
PRO A   8
VAL A  52
None
1.25A 3aqiB-5ddvA:
undetectable
3aqiB-5ddvA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dv5 GNTR FAMILY
TRANSCRIPTIONAL
REGULATOR


(Vibrio
alginolyticus)
PF00392
(GntR)
PF07840
(FadR_C)
5 LEU A 188
PHE A 189
LEU A 192
SER A 124
VAL A 251
None
1.05A 3aqiB-5dv5A:
undetectable
3aqiB-5dv5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gsl 778AA LONG
HYPOTHETICAL
BETA-GALACTOSIDASE


(Pyrococcus
horikoshii)
PF02449
(Glyco_hydro_42)
5 LEU A 472
PHE A 473
LEU A 478
VAL A 487
VAL A 491
None
1.22A 3aqiB-5gslA:
undetectable
3aqiB-5gslA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i5l BACTERIOPHYTOCHROME
PROTEIN


(Agrobacterium
fabrum)
PF00360
(PHY)
PF01590
(GAF)
PF08446
(PAS_2)
5 LEU A  62
LEU A  54
ILE A  76
SER A  51
VAL A 101
None
1.25A 3aqiB-5i5lA:
undetectable
3aqiB-5i5lA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6z SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER


(Homo sapiens)
PF00209
(SNF)
5 LEU A 492
LEU A 491
ILE A 168
SER A 574
PRO A 561
None
1.28A 3aqiB-5i6zA:
undetectable
3aqiB-5i6zA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kqv INSULIN
RECEPTOR,INSULIN
RECEPTOR


(Homo sapiens)
PF00757
(Furin-like)
PF01030
(Recep_L_domain)
5 LEU E 385
PHE E 382
LEU E 419
ILE E 336
SER E 446
None
1.13A 3aqiB-5kqvE:
undetectable
3aqiB-5kqvE:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kzn METABOTROPIC
GLUTAMATE RECEPTOR 2


(Homo sapiens)
PF01094
(ANF_receptor)
PF07562
(NCD3G)
5 LEU A  62
PHE A  38
LEU A  26
ILE A 378
VAL A 385
None
1.19A 3aqiB-5kznA:
4.3
3aqiB-5kznA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nji PHTHIOCEROL/PHENOLPH
THIOCEROL SYNTHESIS
POLYKETIDE SYNTHASE
TYPE I PPSC


(Mycobacterium
tuberculosis)
PF14765
(PS-DH)
5 LEU A 949
LEU A 956
HIS A 928
PRO A1125
VAL A1126
None
1.29A 3aqiB-5njiA:
undetectable
3aqiB-5njiA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE


(Cupriavidus
metallidurans)
no annotation 5 LEU A  87
LEU A  60
MET A  57
VAL A  40
VAL A 121
None
1.14A 3aqiB-5ovuA:
undetectable
3aqiB-5ovuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t0h 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 2


(Homo sapiens)
PF00004
(AAA)
5 LEU f 341
LEU f 326
ILE f 379
SER f 322
VAL f 311
None
1.34A 3aqiB-5t0hf:
undetectable
3aqiB-5t0hf:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uxg ALDEHYDE
DEFORMYLATING
OXYGENASE


(Sulfurisphaera
tokodaii)
no annotation 5 LEU A  89
PHE A  86
LEU A  35
ILE A 109
SER A  39
None
1.33A 3aqiB-5uxgA:
undetectable
3aqiB-5uxgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v8f ORIGIN RECOGNITION
COMPLEX SUBUNIT 2


(Saccharomyces
cerevisiae)
PF04084
(ORC2)
5 LEU B 441
PHE B 437
LEU B 427
ILE B 379
SER B 455
None
1.27A 3aqiB-5v8fB:
undetectable
3aqiB-5v8fB:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7z DNA POLYMERASE III
SUBUNIT BETA


(Rickettsia
conorii)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
5 LEU A 160
LEU A 195
ILE A 130
SER A 238
VAL A 207
None
1.28A 3aqiB-5w7zA:
undetectable
3aqiB-5w7zA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxo PERIPLASMIC
BETA-GLUCOSIDASE


(Bacteroides
thetaiotaomicron)
no annotation 5 LEU A 590
PHE A 591
LEU A 410
ILE A 461
VAL A 398
None
1.31A 3aqiB-5xxoA:
2.5
3aqiB-5xxoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zya SPLICING FACTOR 3B
SUBUNIT 1


(Homo sapiens)
no annotation 5 LEU C 753
LEU C 731
ILE C 721
VAL C 695
VAL C 687
None
1.32A 3aqiB-5zyaC:
undetectable
3aqiB-5zyaC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ap4 DNA POLYMERASE III
SUBUNIT BETA


(Acinetobacter
baumannii)
no annotation 5 LEU A 299
PHE A 301
LEU A 308
SER A 282
VAL A 352
None
1.28A 3aqiB-6ap4A:
undetectable
3aqiB-6ap4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dft -

(-)
no annotation 5 LEU B  86
LEU B 325
ILE B 204
SER B 321
VAL B 280
None
1.32A 3aqiB-6dftB:
undetectable
3aqiB-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g43 PUTATIVE MAJOR
CAPSID PROTEIN


(Cafeteriavirus-dependent
mavirus)
no annotation 5 LEU A  94
PHE A 196
ILE A  92
SER A 102
VAL A 255
None
1.26A 3aqiB-6g43A:
undetectable
3aqiB-6g43A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g4q SUCCINATE--COA
LIGASE [ADP-FORMING]
SUBUNIT BETA,
MITOCHONDRIAL


(Homo sapiens)
no annotation 5 LEU B 243
PHE B 169
MET B 260
ILE B 214
SER B  70
None
1.22A 3aqiB-6g4qB:
undetectable
3aqiB-6g4qB:
undetectable