SIMILAR PATTERNS OF AMINO ACIDS FOR 3AQI_B_CHDB6_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lbq | FERROCHELATASE (Saccharomycescerevisiae) |
PF00762(Ferrochelatase) | 6 | ILE A 313SER A 169PRO A 238VAL A 241VAL A 277TRP A 282 | None | 1.37A | 3aqiB-1lbqA:48.3 | 3aqiB-1lbqA:49.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lbq | FERROCHELATASE (Saccharomycescerevisiae) |
PF00762(Ferrochelatase) | 9 | LEU A 62PHE A 63ILE A 91SER A 169HIS A 235PRO A 238VAL A 241VAL A 277TRP A 282 | None | 0.67A | 3aqiB-1lbqA:48.3 | 3aqiB-1lbqA:49.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lbq | FERROCHELATASE (Saccharomycescerevisiae) |
PF00762(Ferrochelatase) | 5 | MET A 46HIS A 235PRO A 238VAL A 241TRP A 282 | None | 1.06A | 3aqiB-1lbqA:48.3 | 3aqiB-1lbqA:49.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qi7 | PROTEIN(N-GLYCOSIDASE) (Saponariaofficinalis) |
PF00161(RIP) | 5 | LEU A 64PHE A 55ILE A 169VAL A 27VAL A 177 | None | 1.17A | 3aqiB-1qi7A:undetectable | 3aqiB-1qi7A:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ser | PROTEIN (SERYL-TRNASYNTHETASE(E.C.6.1.1.11)) (Thermusthermophilus) |
PF00587(tRNA-synt_2b)PF02403(Seryl_tRNA_N) | 5 | MET A 140LEU A 161LEU A 388ILE A 150VAL A 272 | None | 1.20A | 3aqiB-1serA:undetectable | 3aqiB-1serA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vpv | UPF0230 PROTEINTM1468 (Thermotogamaritima) |
PF02645(DegV) | 5 | LEU A 250PHE A 279LEU A 230ILE A 213SER A 228 | None | 1.28A | 3aqiB-1vpvA:2.0 | 3aqiB-1vpvA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wa5 | IMPORTIN ALPHARE-EXPORTER (Saccharomycescerevisiae) |
PF03378(CAS_CSE1)PF03810(IBN_N)PF08506(Cse1) | 5 | LEU C 41PHE C 61LEU C 38ILE C 109PRO C 79 | None | 1.21A | 3aqiB-1wa5C:undetectable | 3aqiB-1wa5C:17.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wn1 | DIPEPTIDASE (Pyrococcushorikoshii) |
PF00557(Peptidase_M24)PF01321(Creatinase_N) | 5 | LEU A 82LEU A 41ILE A 91PRO A 22VAL A 37 | None | 1.19A | 3aqiB-1wn1A:undetectable | 3aqiB-1wn1A:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wom | SIGMA FACTOR SIGBREGULATION PROTEINRSBQ (Bacillussubtilis) |
PF12697(Abhydrolase_6) | 5 | MET A 251LEU A 176PHE A 180ILE A 221SER A 32 | PGO A 604 (-4.6A)NoneNoneNoneNone | 1.29A | 3aqiB-1womA:0.0 | 3aqiB-1womA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yir | NICOTINATEPHOSPHORIBOSYLTRANSFERASE 2 (Pseudomonasaeruginosa) |
PF04095(NAPRTase) | 5 | LEU A 92PHE A 88LEU A 78ILE A 123PRO A 220 | None | 1.05A | 3aqiB-1yirA:0.0 | 3aqiB-1yirA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zag | PROTEIN(ZINC-ALPHA-2-GLYCOPROTEIN) (Homo sapiens) |
PF00129(MHC_I)PF07654(C1-set) | 5 | LEU A 10LEU A 33SER A 177VAL A 57TRP A 63 | None | 1.23A | 3aqiB-1zagA:undetectable | 3aqiB-1zagA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aeh | FOCAL ADHESIONKINASE 1 (Gallus gallus) |
PF00373(FERM_M) | 5 | LEU A 174PHE A 231LEU A 171PRO A 249VAL A 250 | None | 1.29A | 3aqiB-2aehA:undetectable | 3aqiB-2aehA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aka | DYNAMIN-1 (Rattusnorvegicus) |
PF00350(Dynamin_N)PF01031(Dynamin_M) | 5 | LEU B 48SER B 45PRO B 58VAL B 64VAL B 97 | None | 1.26A | 3aqiB-2akaB:undetectable | 3aqiB-2akaB:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bg9 | ACETYLCHOLINERECEPTOR PROTEIN,ALPHA CHAIN (Torpedomarmorata) |
PF02931(Neur_chan_LBD)PF02932(Neur_chan_memb) | 5 | LEU A 253PHE A 225ILE A 289PRO A 236VAL A 295 | None | 1.32A | 3aqiB-2bg9A:undetectable | 3aqiB-2bg9A:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dyl | DUAL SPECIFICITYMITOGEN-ACTIVATEDPROTEIN KINASEKINASE 7 (Homo sapiens) |
PF00069(Pkinase) | 5 | LEU A 331LEU A 235MET A 238VAL A 404VAL A 413 | None | 1.30A | 3aqiB-2dylA:undetectable | 3aqiB-2dylA:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e3x | COAGULATION FACTORX-ACTIVATING ENZYMEHEAVY CHAIN (Daboiasiamensis) |
PF00200(Disintegrin)PF01421(Reprolysin)PF08516(ADAM_CR) | 5 | LEU A 147MET A 143ILE A 220SER A 148VAL A 168 | NoneNone CA A 802 ( 4.7A)NoneNone | 1.29A | 3aqiB-2e3xA:2.8 | 3aqiB-2e3xA:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e3x | COAGULATION FACTORX-ACTIVATING ENZYMEHEAVY CHAIN (Daboiasiamensis) |
PF00200(Disintegrin)PF01421(Reprolysin)PF08516(ADAM_CR) | 5 | MET A 119LEU A 147MET A 143ILE A 57SER A 148 | None | 1.25A | 3aqiB-2e3xA:2.8 | 3aqiB-2e3xA:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hi4 | CYTOCHROME P450 1A2 (Homo sapiens) |
PF00067(p450) | 5 | LEU A 450PHE A 451LEU A 382ILE A 372VAL A 227 | HEM A 900 (-4.0A)HEM A 900 (-4.1A)HEM A 900 (-4.0A)NoneNone | 1.22A | 3aqiB-2hi4A:undetectable | 3aqiB-2hi4A:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hmi | FAB FRAGMENT OFMONOCLONAL ANTIBODY28 (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | LEU D 69MET D 85ILE D 53PRO D 9VAL D 12 | None | 1.20A | 3aqiB-2hmiD:undetectable | 3aqiB-2hmiD:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nn3 | CASPASE-1 (Spodopterafrugiperda) |
PF00656(Peptidase_C14) | 5 | LEU C 236PHE C 232LEU C 89ILE C 283VAL C 102 | None | 1.29A | 3aqiB-2nn3C:undetectable | 3aqiB-2nn3C:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o8e | DNA MISMATCH REPAIRPROTEIN MSH6 (Homo sapiens) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05190(MutS_IV)PF05192(MutS_III) | 5 | LEU B 655PHE B 643LEU B 638ILE B 570VAL B 688 | None | 1.20A | 3aqiB-2o8eB:undetectable | 3aqiB-2o8eB:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o8e | DNA MISMATCH REPAIRPROTEIN MSH6 (Homo sapiens) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05190(MutS_IV)PF05192(MutS_III) | 5 | LEU B1167LEU B1091ILE B 788SER B1094PRO B1097 | None | 1.33A | 3aqiB-2o8eB:undetectable | 3aqiB-2o8eB:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p4i | ANGIOPOIETIN-1RECEPTOR (Homo sapiens) |
PF07714(Pkinase_Tyr) | 5 | LEU A 910LEU A 914ILE A 980SER A1033PRO A1038 | NoneNoneMR9 A 301 (-4.6A)NoneNone | 1.14A | 3aqiB-2p4iA:undetectable | 3aqiB-2p4iA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qgq | PROTEIN TM_1862 (Thermotogamaritima) |
PF04055(Radical_SAM) | 5 | MET A 241LEU A 233ILE A 144PRO A 254VAL A 255 | None | 1.31A | 3aqiB-2qgqA:undetectable | 3aqiB-2qgqA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uv8 | FATTY ACID SYNTHASESUBUNIT BETA (FAS1) (Saccharomycescerevisiae) |
PF00698(Acyl_transf_1)PF01575(MaoC_dehydratas)PF08354(DUF1729)PF13452(MaoC_dehydrat_N)PF16073(SAT) | 5 | LEU G1960LEU G1904ILE G1967SER G1850VAL G1842 | None | 1.07A | 3aqiB-2uv8G:undetectable | 3aqiB-2uv8G:10.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w45 | ALKALINE EXONUCLEASE (Humangammaherpesvirus4) |
PF01771(Herpes_alk_exo) | 5 | LEU A 23ILE A 127PRO A 39VAL A 32VAL A 458 | None | 1.27A | 3aqiB-2w45A:undetectable | 3aqiB-2w45A:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x66 | PRNB (Pseudomonasfluorescens) |
PF08933(DUF1864) | 5 | LEU A 161PHE A 171LEU A 178VAL A 305VAL A 354 | None | 1.28A | 3aqiB-2x66A:undetectable | 3aqiB-2x66A:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zxq | ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE (Bifidobacteriumlongum) |
PF12905(Glyco_hydro_101)PF17451(Glyco_hyd_101C) | 5 | LEU A 470ILE A 354SER A 528PRO A 592VAL A 425 | None | 1.05A | 3aqiB-2zxqA:undetectable | 3aqiB-2zxqA:13.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a0g | HEMOGLOBIN SUBUNITALPHA (Cavia porcellus) |
PF00042(Globin) | 5 | LEU A 29PHE A 33LEU A 101ILE A 46HIS A 87 | NoneNoneHEM A 201 (-4.1A)NoneHEM A 201 (-3.3A) | 1.23A | 3aqiB-3a0gA:undetectable | 3aqiB-3a0gA:17.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3abb | CYTOCHROME P450HYDROXYLASE (Streptomycesavermitilis) |
PF00067(p450) | 5 | LEU A 284LEU A 363ILE A 318PRO A 154VAL A 153 | None | 1.30A | 3aqiB-3abbA:undetectable | 3aqiB-3abbA:24.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3aqi | FERROCHELATASE (Homo sapiens) |
PF00762(Ferrochelatase) | 12 | MET A 76LEU A 92PHE A 93LEU A 98MET A 99ILE A 119SER A 197HIS A 263PRO A 266VAL A 269VAL A 305TRP A 310 | CHD A 1 ( 3.8A)CHD A 1 (-4.8A)CHD A 1 ( 4.7A)CHD A 1 (-4.3A)CHD A 2 (-4.0A)NoneCHD A 1 (-3.0A)CHD A 1 (-4.3A)CHD A 2 ( 4.5A)NoneCHD A 1 ( 4.9A)CHD A 2 (-4.7A) | 0.30A | 3aqiB-3aqiA:61.5 | 3aqiB-3aqiA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bj5 | PROTEINDISULFIDE-ISOMERASE (Homo sapiens) |
PF13848(Thioredoxin_6) | 5 | LEU A 255ILE A 269PRO A 296VAL A 248VAL A 298 | None | 1.33A | 3aqiB-3bj5A:undetectable | 3aqiB-3bj5A:15.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bvc | UNCHARACTERIZEDPROTEIN ISM_01780 (Roseovariusnubinhibens) |
PF13759(2OG-FeII_Oxy_5) | 5 | LEU A 105LEU A 80ILE A 38SER A 79VAL A 132 | None | 1.24A | 3aqiB-3bvcA:undetectable | 3aqiB-3bvcA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cia | COLD-ACTIVEAMINOPEPTIDASE (Colwelliapsychrerythraea) |
PF01433(Peptidase_M1)PF09127(Leuk-A4-hydro_C) | 5 | LEU A 529PHE A 525LEU A 562SER A 563VAL A 571 | None | 1.08A | 3aqiB-3ciaA:undetectable | 3aqiB-3ciaA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3do6 | FORMATE--TETRAHYDROFOLATE LIGASE (Thermotogamaritima) |
PF01268(FTHFS) | 5 | LEU A 13LEU A 279MET A 275ILE A 4SER A 280 | None | 1.31A | 3aqiB-3do6A:1.5 | 3aqiB-3do6A:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fms | TRANSCRIPTIONALREGULATOR, GNTRFAMILY (Thermotogamaritima) |
PF00392(GntR)PF07729(FCD) | 5 | LEU A 193LEU A 197ILE A 101VAL A 160TRP A 154 | None | 1.24A | 3aqiB-3fmsA:undetectable | 3aqiB-3fmsA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gg9 | D-3-PHOSPHOGLYCERATEDEHYDROGENASEOXIDOREDUCTASEPROTEIN (Ralstoniasolanacearum) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | LEU A 221PHE A 222ILE A 241HIS A 231VAL A 128 | None | 1.34A | 3aqiB-3gg9A:6.0 | 3aqiB-3gg9A:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h6e | CARBOHYDRATE KINASE,FGGY (Novosphingobiumaromaticivorans) |
PF00370(FGGY_N) | 5 | LEU A 374LEU A 408ILE A 336SER A 407VAL A 329 | None | 1.33A | 3aqiB-3h6eA:undetectable | 3aqiB-3h6eA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i6s | SUBTILISIN-LIKEPROTEASE (Solanumlycopersicum) |
PF00082(Peptidase_S8) | 5 | LEU A 660LEU A 494ILE A 722SER A 490PRO A 330 | None | 1.13A | 3aqiB-3i6sA:undetectable | 3aqiB-3i6sA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j8g | GTPASE DER (Escherichiacoli) |
PF01926(MMR_HSR1)PF14714(KH_dom-like) | 5 | LEU X 7ILE X 143PRO X 3VAL X 158TRP X 162 | None | 1.27A | 3aqiB-3j8gX:undetectable | 3aqiB-3j8gX:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l6a | EUKARYOTICTRANSLATIONINITIATION FACTOR 4GAMMA 2 (Homo sapiens) |
PF02020(W2)PF02847(MA3) | 5 | LEU A 89LEU A 128ILE A 49VAL A 162VAL A 119 | NoneNoneNoneMES A 361 (-3.6A)None | 1.16A | 3aqiB-3l6aA:undetectable | 3aqiB-3l6aA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lly | AGGLUTININ ALPHACHAIN (Maclurapomifera) |
PF01419(Jacalin) | 5 | LEU A 28LEU A 124ILE A 12VAL A 72VAL A 68 | None | 0.95A | 3aqiB-3llyA:undetectable | 3aqiB-3llyA:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lnb | N-ACETYLTRANSFERASEFAMILY PROTEIN (Bacillusanthracis) |
PF00797(Acetyltransf_2) | 5 | LEU A 60LEU A 56ILE A 266SER A 74VAL A 201 | None | 1.17A | 3aqiB-3lnbA:undetectable | 3aqiB-3lnbA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m1m | ORF904 (Sulfolobusislandicus) |
PF09250(Prim-Pol)PF13010(pRN1_helical) | 5 | LEU A 228PHE A 162LEU A 110PRO A 154TRP A 246 | None | 1.09A | 3aqiB-3m1mA:undetectable | 3aqiB-3m1mA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ojc | PUTATIVEASPARTATE/GLUTAMATERACEMASE (Yersinia pestis) |
PF01177(Asp_Glu_race) | 5 | MET A 130LEU A 186ILE A 161VAL A 212VAL A 205 | None | 1.22A | 3aqiB-3ojcA:5.0 | 3aqiB-3ojcA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p8a | UNCHARACTERIZEDPROTEIN (Staphylococcusaureus) |
PF13468(Glyoxalase_3) | 5 | LEU A 112PHE A 212LEU A 228MET A 214VAL A 196 | None | 1.32A | 3aqiB-3p8aA:undetectable | 3aqiB-3p8aA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s2j | DIPEPTIDASE (Streptomycescoelicolor) |
PF01244(Peptidase_M19) | 5 | LEU A 354LEU A 345ILE A 317SER A 3VAL A 296 | None | 1.22A | 3aqiB-3s2jA:undetectable | 3aqiB-3s2jA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sxm | TRANSCRIPTIONALREGULATOR, GNTRFAMILY (Thermotogamaritima) |
PF07729(FCD) | 5 | LEU A 193LEU A 197ILE A 101VAL A 160TRP A 154 | None | 1.28A | 3aqiB-3sxmA:undetectable | 3aqiB-3sxmA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4o | MUCOSA-ASSOCIATEDLYMPHOID TISSUELYMPHOMATRANSLOCATIONPROTEIN 1 (Homo sapiens) |
PF00656(Peptidase_C14) | 5 | LEU A 515PHE A 511ILE A 550VAL A 380VAL A 458 | None | 1.18A | 3aqiB-3v4oA:undetectable | 3aqiB-3v4oA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4o | MUCOSA-ASSOCIATEDLYMPHOID TISSUELYMPHOMATRANSLOCATIONPROTEIN 1 (Homo sapiens) |
PF00656(Peptidase_C14) | 5 | LEU A 515PHE A 511LEU A 369ILE A 550VAL A 380 | None | 1.25A | 3aqiB-3v4oA:undetectable | 3aqiB-3v4oA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vfd | SPASTIN (Homo sapiens) |
PF00004(AAA)PF09336(Vps4_C) | 5 | LEU A 354LEU A 378MET A 484ILE A 344VAL A 443 | None | 1.33A | 3aqiB-3vfdA:undetectable | 3aqiB-3vfdA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3woh | SIAM (Streptomycessp. A7248) |
PF13561(adh_short_C2) | 5 | LEU A 119PHE A 123LEU A 166SER A 145VAL A 240 | None | 1.27A | 3aqiB-3wohA:2.8 | 3aqiB-3wohA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zyi | LEUCINE-RICHREPEAT-CONTAININGPROTEIN 4 (Homo sapiens) |
PF07679(I-set)PF13855(LRR_8) | 5 | LEU A 104PHE A 95LEU A 125ILE A 87VAL A 170 | None | 1.18A | 3aqiB-3zyiA:undetectable | 3aqiB-3zyiA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4boo | ACETYLCHOLINERECEPTOR SUBUNITALPHA (Torpedomarmorata) |
PF02931(Neur_chan_LBD)PF02932(Neur_chan_memb) | 5 | LEU A 253PHE A 225ILE A 289PRO A 236VAL A 295 | None | 1.31A | 3aqiB-4booA:undetectable | 3aqiB-4booA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bv4 | PROTEIN TOLL,VARIABLE LYMPHOCYTERECEPTOR B CHIMERA (Drosophilamelanogaster;Eptatretusburgeri) |
PF11921(DUF3439)PF13855(LRR_8) | 5 | PHE R 193LEU R 199MET R 220ILE R 185SER R 177 | None | 1.29A | 3aqiB-4bv4R:undetectable | 3aqiB-4bv4R:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cr4 | 26S PROTEASE SUBUNITRPT4 (Saccharomycescerevisiae) |
PF00004(AAA) | 5 | MET L 312LEU L 337LEU L 343ILE L 286VAL L 196 | None | 1.33A | 3aqiB-4cr4L:undetectable | 3aqiB-4cr4L:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eut | SERINE/THREONINE-PROTEIN KINASE TBK1 (Homo sapiens) |
PF00069(Pkinase) | 5 | MET A 263LEU A 277LEU A 269ILE A 284SER A 268 | None | 0.99A | 3aqiB-4eutA:undetectable | 3aqiB-4eutA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4euu | SERINE/THREONINE-PROTEIN KINASE TBK1 (Homo sapiens) |
PF00069(Pkinase) | 5 | MET A 263LEU A 277LEU A 269ILE A 284SER A 268 | None | 1.03A | 3aqiB-4euuA:undetectable | 3aqiB-4euuA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fod | ALK TYROSINE KINASERECEPTOR (Homo sapiens) |
PF07714(Pkinase_Tyr) | 5 | LEU A1204LEU A1208ILE A1268SER A1324PRO A1329 | NoneNoneNoneGOL A1502 ( 4.7A)None | 1.30A | 3aqiB-4fodA:undetectable | 3aqiB-4fodA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gt6 | CELL SURFACE PROTEIN (Faecalibacteriumprausnitzii) |
PF13306(LRR_5) | 5 | PHE A 136LEU A 165ILE A 97VAL A 191VAL A 151 | NoneNoneNoneEDO A 908 (-4.5A)None | 1.27A | 3aqiB-4gt6A:undetectable | 3aqiB-4gt6A:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hq1 | PROBABLE RECEPTORPROTEIN KINASE TMK1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 5 | LEU A 84LEU A 87ILE A 100PRO A 52TRP A 55 | None | 1.26A | 3aqiB-4hq1A:undetectable | 3aqiB-4hq1A:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i1p | MUCOSA-ASSOCIATEDLYMPHOID TISSUELYMPHOMATRANSLOCATIONPROTEIN 1 (Homo sapiens) |
PF00656(Peptidase_C14) | 6 | LEU A 515PHE A 511LEU A 369ILE A 550VAL A 380VAL A 458 | None | 1.39A | 3aqiB-4i1pA:undetectable | 3aqiB-4i1pA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4maf | ATP SULFURYLASE (Glycine max) |
PF01747(ATP-sulfurylase)PF14306(PUA_2) | 5 | LEU A 189LEU A 363MET A 354ILE A 196PRO A 327 | None | 1.31A | 3aqiB-4mafA:undetectable | 3aqiB-4mafA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mxe | N-ACETYLTRANSFERASEESCO1 (Homo sapiens) |
PF13880(Acetyltransf_13) | 5 | LEU A 791LEU A 709MET A 669ILE A 766VAL A 682 | None | 1.28A | 3aqiB-4mxeA:undetectable | 3aqiB-4mxeA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nky | STEROID17-ALPHA-HYDROXYLASE/17,20 LYASE (Homo sapiens) |
PF00067(p450) | 5 | MET A 68LEU A 217LEU A 40ILE A 393SER A 39 | None | 1.20A | 3aqiB-4nkyA:undetectable | 3aqiB-4nkyA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4npk | EXTENDEDSYNAPTOTAGMIN-2 (Homo sapiens) |
PF00168(C2) | 5 | LEU A 458LEU A 397ILE A 418SER A 435TRP A 488 | None | 1.16A | 3aqiB-4npkA:undetectable | 3aqiB-4npkA:24.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o1s | V-TYPE ATP SYNTHASEALPHA CHAIN (Thermoplasmavolcanium) |
PF14890(Intein_splicing) | 5 | LEU A 97LEU A 167ILE A 137PRO A 11VAL A 12 | None | 1.33A | 3aqiB-4o1sA:undetectable | 3aqiB-4o1sA:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p42 | EXTENDEDSYNAPTOTAGMIN-2 (Homo sapiens) |
PF00168(C2)PF17047(SMP_LBD) | 5 | LEU A 430LEU A 369ILE A 390SER A 407TRP A 460 | None | 1.12A | 3aqiB-4p42A:undetectable | 3aqiB-4p42A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q22 | GLYCOSIDE HYDROLASEFAMILY 18 (Serratiaproteamaculans) |
PF00704(Glyco_hydro_18) | 5 | LEU A 180LEU A 177ILE A 82PRO A 155VAL A 205 | None | 1.24A | 3aqiB-4q22A:undetectable | 3aqiB-4q22A:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qax | 2,3-BISPHOSPHOGLYCERATE-INDEPENDENTPHOSPHOGLYCERATEMUTASE (Staphylococcusaureus) |
PF01676(Metalloenzyme)PF06415(iPGM_N) | 5 | LEU A 485LEU A 488ILE A 69VAL A 470VAL A 463 | None | 1.32A | 3aqiB-4qaxA:undetectable | 3aqiB-4qaxA:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u7l | LEUCINE-RICH REPEATSANDIMMUNOGLOBULIN-LIKEDOMAINS PROTEIN 1 (Homo sapiens) |
PF01463(LRRCT)PF13855(LRR_8) | 5 | LEU A 371LEU A 392MET A 389ILE A 354TRP A 410 | None | 1.30A | 3aqiB-4u7lA:undetectable | 3aqiB-4u7lA:23.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u7l | LEUCINE-RICH REPEATSANDIMMUNOGLOBULIN-LIKEDOMAINS PROTEIN 1 (Homo sapiens) |
PF01463(LRRCT)PF13855(LRR_8) | 5 | LEU A 371LEU A 392MET A 389VAL A 381TRP A 410 | None | 1.19A | 3aqiB-4u7lA:undetectable | 3aqiB-4u7lA:23.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ypv | EST8 (Parvibaculum) |
PF07859(Abhydrolase_3) | 5 | LEU A 239LEU A 242SER A 169VAL A 155VAL A 247 | None | 1.23A | 3aqiB-4ypvA:2.8 | 3aqiB-4ypvA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z0c | TOLL-LIKE RECEPTOR13 (Mus musculus) |
PF00560(LRR_1)PF13516(LRR_6)PF13855(LRR_8) | 5 | LEU A 156PHE A 147LEU A 176ILE A 139VAL A 166 | None | 1.26A | 3aqiB-4z0cA:undetectable | 3aqiB-4z0cA:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z64 | SOMATICEMBRYOGENESISRECEPTOR KINASE 1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 5 | LEU C 146LEU C 170ILE C 109SER C 194VAL C 205 | None | 1.26A | 3aqiB-4z64C:undetectable | 3aqiB-4z64C:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z6k | ALCOHOLDEHYDROGENASE (Moraxella sp.TAE123) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | LEU A 251LEU A 257ILE A 228VAL A 239VAL A 194 | None | 1.27A | 3aqiB-4z6kA:undetectable | 3aqiB-4z6kA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zrq | TRANSCOBALAMIN-2 (Homo sapiens) |
PF01122(Cobalamin_bind)PF14478(DUF4430) | 5 | LEU A 144LEU A 183PRO A 276VAL A 277VAL A 38 | None | 1.29A | 3aqiB-4zrqA:undetectable | 3aqiB-4zrqA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxb | INSULIN RECEPTOR (Homo sapiens) |
PF00041(fn3)PF00757(Furin-like)PF01030(Recep_L_domain) | 5 | LEU E 385PHE E 382LEU E 419ILE E 336SER E 446 | None | 1.12A | 3aqiB-4zxbE:undetectable | 3aqiB-4zxbE:17.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b4x | REELIN (Mus musculus) |
PF07974(EGF_2) | 5 | PHE A2265LEU A2261ILE A2309PRO A2282VAL A2227 | None | 1.31A | 3aqiB-5b4xA:undetectable | 3aqiB-5b4xA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cni | METABOTROPICGLUTAMATE RECEPTOR 2 (Homo sapiens) |
PF01094(ANF_receptor) | 5 | LEU A 62PHE A 38LEU A 26ILE A 378VAL A 385 | None | 1.16A | 3aqiB-5cniA:2.8 | 3aqiB-5cniA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d3m | ENERGY-COUPLINGFACTOR TRANSPORTERATP-BINDING PROTEINECFA2 (Lactobacillusdelbrueckii) |
PF00005(ABC_tran) | 5 | LEU B 26PHE B 28LEU B 218ILE B 64SER B 44 | NoneNoneNoneNoneANP B 301 (-3.4A) | 1.01A | 3aqiB-5d3mB:undetectable | 3aqiB-5d3mB:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ddv | 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATECYTIDYLYLTRANSFERASE (Bacillussubtilis) |
PF01128(IspD) | 5 | LEU A 169PHE A 164LEU A 91PRO A 8VAL A 52 | None | 1.25A | 3aqiB-5ddvA:undetectable | 3aqiB-5ddvA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dv5 | GNTR FAMILYTRANSCRIPTIONALREGULATOR (Vibrioalginolyticus) |
PF00392(GntR)PF07840(FadR_C) | 5 | LEU A 188PHE A 189LEU A 192SER A 124VAL A 251 | None | 1.05A | 3aqiB-5dv5A:undetectable | 3aqiB-5dv5A:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gsl | 778AA LONGHYPOTHETICALBETA-GALACTOSIDASE (Pyrococcushorikoshii) |
PF02449(Glyco_hydro_42) | 5 | LEU A 472PHE A 473LEU A 478VAL A 487VAL A 491 | None | 1.22A | 3aqiB-5gslA:undetectable | 3aqiB-5gslA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i5l | BACTERIOPHYTOCHROMEPROTEIN (Agrobacteriumfabrum) |
PF00360(PHY)PF01590(GAF)PF08446(PAS_2) | 5 | LEU A 62LEU A 54ILE A 76SER A 51VAL A 101 | None | 1.25A | 3aqiB-5i5lA:undetectable | 3aqiB-5i5lA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i6z | SODIUM-DEPENDENTSEROTONINTRANSPORTER (Homo sapiens) |
PF00209(SNF) | 5 | LEU A 492LEU A 491ILE A 168SER A 574PRO A 561 | None | 1.28A | 3aqiB-5i6zA:undetectable | 3aqiB-5i6zA:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kqv | INSULINRECEPTOR,INSULINRECEPTOR (Homo sapiens) |
PF00757(Furin-like)PF01030(Recep_L_domain) | 5 | LEU E 385PHE E 382LEU E 419ILE E 336SER E 446 | None | 1.13A | 3aqiB-5kqvE:undetectable | 3aqiB-5kqvE:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kzn | METABOTROPICGLUTAMATE RECEPTOR 2 (Homo sapiens) |
PF01094(ANF_receptor)PF07562(NCD3G) | 5 | LEU A 62PHE A 38LEU A 26ILE A 378VAL A 385 | None | 1.19A | 3aqiB-5kznA:4.3 | 3aqiB-5kznA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nji | PHTHIOCEROL/PHENOLPHTHIOCEROL SYNTHESISPOLYKETIDE SYNTHASETYPE I PPSC (Mycobacteriumtuberculosis) |
PF14765(PS-DH) | 5 | LEU A 949LEU A 956HIS A 928PRO A1125VAL A1126 | None | 1.29A | 3aqiB-5njiA:undetectable | 3aqiB-5njiA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ovu | BETA-PROTEOBACTERIAPROTEASOME HOMOLOGUE (Cupriavidusmetallidurans) |
no annotation | 5 | LEU A 87LEU A 60MET A 57VAL A 40VAL A 121 | None | 1.14A | 3aqiB-5ovuA:undetectable | 3aqiB-5ovuA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t0h | 26S PROTEASOMENON-ATPASEREGULATORY SUBUNIT 2 (Homo sapiens) |
PF00004(AAA) | 5 | LEU f 341LEU f 326ILE f 379SER f 322VAL f 311 | None | 1.34A | 3aqiB-5t0hf:undetectable | 3aqiB-5t0hf:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uxg | ALDEHYDEDEFORMYLATINGOXYGENASE (Sulfurisphaeratokodaii) |
no annotation | 5 | LEU A 89PHE A 86LEU A 35ILE A 109SER A 39 | None | 1.33A | 3aqiB-5uxgA:undetectable | 3aqiB-5uxgA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v8f | ORIGIN RECOGNITIONCOMPLEX SUBUNIT 2 (Saccharomycescerevisiae) |
PF04084(ORC2) | 5 | LEU B 441PHE B 437LEU B 427ILE B 379SER B 455 | None | 1.27A | 3aqiB-5v8fB:undetectable | 3aqiB-5v8fB:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7z | DNA POLYMERASE IIISUBUNIT BETA (Rickettsiaconorii) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | LEU A 160LEU A 195ILE A 130SER A 238VAL A 207 | None | 1.28A | 3aqiB-5w7zA:undetectable | 3aqiB-5w7zA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xxo | PERIPLASMICBETA-GLUCOSIDASE (Bacteroidesthetaiotaomicron) |
no annotation | 5 | LEU A 590PHE A 591LEU A 410ILE A 461VAL A 398 | None | 1.31A | 3aqiB-5xxoA:2.5 | 3aqiB-5xxoA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zya | SPLICING FACTOR 3BSUBUNIT 1 (Homo sapiens) |
no annotation | 5 | LEU C 753LEU C 731ILE C 721VAL C 695VAL C 687 | None | 1.32A | 3aqiB-5zyaC:undetectable | 3aqiB-5zyaC:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ap4 | DNA POLYMERASE IIISUBUNIT BETA (Acinetobacterbaumannii) |
no annotation | 5 | LEU A 299PHE A 301LEU A 308SER A 282VAL A 352 | None | 1.28A | 3aqiB-6ap4A:undetectable | 3aqiB-6ap4A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dft | - (-) |
no annotation | 5 | LEU B 86LEU B 325ILE B 204SER B 321VAL B 280 | None | 1.32A | 3aqiB-6dftB:undetectable | 3aqiB-6dftB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g43 | PUTATIVE MAJORCAPSID PROTEIN (Cafeteriavirus-dependentmavirus) |
no annotation | 5 | LEU A 94PHE A 196ILE A 92SER A 102VAL A 255 | None | 1.26A | 3aqiB-6g43A:undetectable | 3aqiB-6g43A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g4q | SUCCINATE--COALIGASE [ADP-FORMING]SUBUNIT BETA,MITOCHONDRIAL (Homo sapiens) |
no annotation | 5 | LEU B 243PHE B 169MET B 260ILE B 214SER B 70 | None | 1.22A | 3aqiB-6g4qB:undetectable | 3aqiB-6g4qB:undetectable |