SIMILAR PATTERNS OF AMINO ACIDS FOR 3AOD_A_MIYA2001

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1br2 MYOSIN

(Gallus gallus) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		4 GLY A 588
GLU A 487
ASN A 483
ILE A 471
 None
 0.96A 3aodA-1br2A:
1.4		 3aodA-1br2A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ebd DIHYDROLIPOAMIDE
DEHYDROGENASE

(Geobacillus
stearothermophilus) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 GLY A 427
GLU A 431
ILE A 409
ALA A 412
 None
 0.77A 3aodA-1ebdA:
0.0		 3aodA-1ebdA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fft UBIQUINOL OXIDASE

(Escherichia
coli) 		PF00116
(COX2)
PF06481
(COX_ARM) 		4 SER B  42
ILE B 183
ALA B 185
PHE B 163
 None
 0.94A 3aodA-1fftB:
0.0		 3aodA-1fftB:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fi8 NATURAL KILLER CELL
PROTEASE 1

(Rattus
norvegicus) 		PF00089
(Trypsin) 		4 GLY A  44
ILE A 212
ALA A  55
PHE A 228
 None
 0.92A 3aodA-1fi8A:
0.0		 3aodA-1fi8A:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8x MYOSIN II HEAVY
CHAIN FUSED TO
ALPHA-ACTININ 3

(Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N) 		4 GLY A 575
GLU A 476
ASN A 472
ILE A 460
 None
 0.94A 3aodA-1g8xA:
0.0		 3aodA-1g8xA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gvz KALLIKREIN-1E2

(Equus caballus) 		PF00089
(Trypsin) 		4 GLY A  44
ILE A 212
ALA A  55
PHE A 228
 None
 0.93A 3aodA-1gvzA:
0.0		 3aodA-1gvzA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h7w DIHYDROPYRIMIDINE
DEHYDROGENASE

(Sus scrofa) 		PF01180
(DHO_dh)
PF07992
(Pyr_redox_2)
PF14691
(Fer4_20)
PF14697
(Fer4_21) 		4 PHE A 564
GLY A 567
ILE A 543
PHE A 542
 None
 0.88A 3aodA-1h7wA:
0.0		 3aodA-1h7wA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hcu ALPHA-1,2-MANNOSIDAS
E

(Trichoderma
reesei) 		PF01532
(Glyco_hydro_47) 		4 SER A 446
GLY A 351
ILE A 421
ALA A 417
 None
 0.95A 3aodA-1hcuA:
0.0		 3aodA-1hcuA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hqk 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE

(Aquifex
aeolicus) 		PF00885
(DMRL_synthase) 		4 GLY A  99
GLU A  95
ILE A  59
ALA A  63
 None
 0.93A 3aodA-1hqkA:
0.0		 3aodA-1hqkA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN

(Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF01576
(Myosin_tail_1)
PF02736
(Myosin_N) 		4 GLY S 588
GLU S 487
ASN S 483
ILE S 471
 None
 0.90A 3aodA-1i84S:
undetectable		 3aodA-1i84S:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN

(Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF01576
(Myosin_tail_1)
PF02736
(Myosin_N) 		4 SER S 246
GLU S 185
ILE S 191
ALA S 195
 None
 0.95A 3aodA-1i84S:
undetectable		 3aodA-1i84S:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ihc GEPHYRIN

(Rattus
norvegicus) 		PF00994
(MoCF_biosynth) 		5 GLY A 110
GLU A 107
ILE A 158
ALA A 161
PHE A 157
 None
 1.31A 3aodA-1ihcA:
undetectable		 3aodA-1ihcA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j1w ISOCITRATE
DEHYDROGENASE

(Azotobacter
vinelandii) 		PF03971
(IDH) 		4 SER A 184
GLY A 433
ILE A 429
PHE A 427
 None
 0.75A 3aodA-1j1wA:
undetectable		 3aodA-1j1wA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j2r HYPOTHETICAL
ISOCHORISMATASE
FAMILY PROTEIN YECD

(Escherichia
coli) 		PF00857
(Isochorismatase) 		4 SER A 178
PHE A 118
GLY A 116
ILE A  25
 None
 0.91A 3aodA-1j2rA:
undetectable		 3aodA-1j2rA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k1d D-HYDANTOINASE

(Geobacillus
stearothermophilus) 		PF01979
(Amidohydro_1) 		5 PHE A  74
GLY A  77
GLU A 343
ILE A 118
ALA A 116
 None
 1.43A 3aodA-1k1dA:
undetectable		 3aodA-1k1dA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kag SHIKIMATE KINASE I

(Escherichia
coli) 		PF01202
(SKI) 		4 SER A  18
PHE A  51
GLY A  48
ILE A  39
 None
 0.81A 3aodA-1kagA:
undetectable		 3aodA-1kagA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ksq LATENT TRANSFORMING
GROWTH FACTOR BETA
BINDING PROTEIN 1

(Homo sapiens) 		PF00683
(TB) 		4 PHE A  50
GLY A  42
ASN A  24
ALA A  19
 None
 0.85A 3aodA-1ksqA:
undetectable		 3aodA-1ksqA:
4.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mc3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E

(Escherichia
coli) 		PF00483
(NTP_transferase) 		4 PHE A  96
GLY A  93
ILE A  52
ALA A  78
 None
 0.84A 3aodA-1mc3A:
undetectable		 3aodA-1mc3A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mw9 DNA TOPOISOMERASE I

(Escherichia
coli) 		PF01131
(Topoisom_bac)
PF01751
(Toprim) 		4 GLY X 128
GLU X 125
ILE X 106
ALA X 100
 None
 0.83A 3aodA-1mw9X:
undetectable		 3aodA-1mw9X:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n7d LOW-DENSITY
LIPOPROTEIN RECEPTOR

(Homo sapiens) 		PF00057
(Ldl_recept_a)
PF00058
(Ldl_recept_b)
PF07645
(EGF_CA)
PF14670
(FXa_inhibition) 		4 GLY A 642
GLU A 647
ASN A 644
ILE A 463
 None
 0.91A 3aodA-1n7dA:
undetectable		 3aodA-1n7dA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1np8 CALCIUM-DEPENDENT
PROTEASE, SMALL
SUBUNIT

(Rattus
norvegicus) 		PF13833
(EF-hand_8) 		4 PHE A 114
GLY A 112
ILE A  93
ALA A 117
 None
 0.93A 3aodA-1np8A:
undetectable		 3aodA-1np8A:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1obb ALPHA-GLUCOSIDASE

(Thermotoga
maritima) 		PF02056
(Glyco_hydro_4)
PF11975
(Glyco_hydro_4C) 		4 GLY A 158
ILE A 155
ALA A 152
PHE A 173
 None
None
NAD  A 500 (-3.5A)
None
 0.97A 3aodA-1obbA:
undetectable		 3aodA-1obbA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ogo DEXTRANASE

(Talaromyces
minioluteus) 		PF03718
(Glyco_hydro_49)
PF17433
(Glyco_hydro_49N) 		5 GLY X 377
GLU X 379
ASN X 348
ALA X 370
PHE X 373
 None
None
None
None
GLC  X1576 ( 4.1A)
 1.14A 3aodA-1ogoX:
undetectable		 3aodA-1ogoX:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1olx 2-OXOISOVALERATE
DEHYDROGENASE BETA
SUBUNIT

(Homo sapiens) 		PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 PHE B  82
GLY B  81
GLU B 113
ALA B  95
 None
 0.85A 3aodA-1olxB:
undetectable		 3aodA-1olxB:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pek PROTEINASE K

(Parengyodontium
album) 		PF00082
(Peptidase_S8) 		4 GLY E  75
GLU E  48
ILE E  42
PHE E  91
 None
 0.93A 3aodA-1pekE:
undetectable		 3aodA-1pekE:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qlb FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT

(Wolinella
succinogenes) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		4 GLY A 236
GLU A 242
ILE A 375
ALA A 394
 FAD  A1656 ( 4.5A)
None
None
None
 0.84A 3aodA-1qlbA:
undetectable		 3aodA-1qlbA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rk2 RIBOKINASE

(Escherichia
coli) 		PF00294
(PfkB) 		5 SER A  12
PHE A 257
GLY A 259
ASN A  46
ALA A 282
 None
ADP  A 310 ( 4.4A)
None
RIB  A 311 (-3.3A)
ADP  A 310 (-3.3A)
 1.46A 3aodA-1rk2A:
undetectable		 3aodA-1rk2A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rvv RIBOFLAVIN SYNTHASE

(Bacillus
subtilis) 		no annotation 4 GLY A  99
GLU A  95
ILE A  59
ALA A  63
 None
 0.90A 3aodA-1rvvA:
undetectable		 3aodA-1rvvA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rxm DNA POLYMERASE
SLIDING CLAMP

(Archaeoglobus
fulgidus) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 GLY A 160
GLU A 180
ILE A 131
ALA A 129
 None
 0.92A 3aodA-1rxmA:
undetectable		 3aodA-1rxmA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u31 NAD(P)
TRANSHYDROGENASE,
MITOCHONDRIAL

(Homo sapiens) 		PF02233
(PNTB) 		4 GLY A  92
ILE A  83
ALA A  87
PHE A  81
 None
None
NDP  A 300 (-4.9A)
None
 0.96A 3aodA-1u31A:
undetectable		 3aodA-1u31A:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ulz PYRUVATE CARBOXYLASE
N-TERMINAL DOMAIN

(Aquifex
aeolicus) 		PF00289
(Biotin_carb_N)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 PHE A  83
GLU A  89
ILE A  65
ALA A   8
 None
 0.96A 3aodA-1ulzA:
undetectable		 3aodA-1ulzA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5b 3-ISOPROPYLMALATE
DEHYDROGENASE

(Bacillus
coagulans) 		PF00180
(Iso_dh) 		4 SER A 266
GLY A  91
ILE A  43
ALA A  47
 None
 0.89A 3aodA-1v5bA:
undetectable		 3aodA-1v5bA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vcw PROTEASE DEGS

(Escherichia
coli) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		4 GLY A  82
ASN A  94
ILE A 215
ALA A 204
 None
 0.96A 3aodA-1vcwA:
undetectable		 3aodA-1vcwA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vm7 RIBOKINASE

(Thermotoga
maritima) 		PF00294
(PfkB) 		4 GLY A 216
GLU A 179
ASN A 178
ALA A 273
 None
 0.96A 3aodA-1vm7A:
undetectable		 3aodA-1vm7A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vm7 RIBOKINASE

(Thermotoga
maritima) 		PF00294
(PfkB) 		5 SER A  10
PHE A 248
GLY A 250
ASN A  44
ALA A 273
 None
 1.41A 3aodA-1vm7A:
undetectable		 3aodA-1vm7A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w5d PENICILLIN-BINDING
PROTEIN

(Bacillus
subtilis) 		PF02113
(Peptidase_S13) 		4 SER A 277
GLY A  95
GLU A  75
ALA A 249
 None
 0.86A 3aodA-1w5dA:
undetectable		 3aodA-1w5dA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wa5 IMPORTIN ALPHA
RE-EXPORTER
IMPORTIN ALPHA
SUBUNIT

(Saccharomyces
cerevisiae) 		PF00514
(Arm)
PF01749
(IBB)
PF03378
(CAS_CSE1)
PF03810
(IBN_N)
PF08506
(Cse1)
PF16186
(Arm_3) 		4 GLY C 442
GLU B 478
ASN C 437
ILE C 434
 None
 0.92A 3aodA-1wa5C:
undetectable		 3aodA-1wa5C:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x0u HYPOTHETICAL
METHYLMALONYL-COA
DECARBOXYLASE ALPHA
SUBUNIT

(Sulfurisphaera
tokodaii) 		PF01039
(Carboxyl_trans) 		4 GLY A 144
GLU A  69
ILE A 141
ALA A 139
 None
 0.80A 3aodA-1x0uA:
undetectable		 3aodA-1x0uA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x0u HYPOTHETICAL
METHYLMALONYL-COA
DECARBOXYLASE ALPHA
SUBUNIT

(Sulfurisphaera
tokodaii) 		PF01039
(Carboxyl_trans) 		4 PHE A 338
GLY A 340
ILE A 342
ALA A 346
 None
 0.94A 3aodA-1x0uA:
undetectable		 3aodA-1x0uA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xc6 BETA-GALACTOSIDASE

(Penicillium sp.) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		4 GLY A 302
ASN A 341
ILE A 345
PHE A 346
 None
 0.94A 3aodA-1xc6A:
undetectable		 3aodA-1xc6A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xo8 AT1G01470

(Arabidopsis
thaliana) 		PF03168
(LEA_2) 		4 GLY A  24
ASN A  49
ILE A 124
PHE A 132
 None
 0.82A 3aodA-1xo8A:
undetectable		 3aodA-1xo8A:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xrs D-LYSINE
5,6-AMINOMUTASE
ALPHA SUBUNIT

(Acetoanaerobium
sticklandii) 		PF09043
(Lys-AminoMut_A) 		4 GLY A 249
ILE A 285
ALA A 289
PHE A 509
 None
 0.88A 3aodA-1xrsA:
undetectable		 3aodA-1xrsA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z2z PROBABLE TRNA
PSEUDOURIDINE
SYNTHASE D

(Methanosarcina
mazei) 		PF01142
(TruD) 		4 PHE A 269
GLY A 186
GLU A 191
PHE A 376
 None
 0.79A 3aodA-1z2zA:
2.1		 3aodA-1z2zA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z6r MLC PROTEIN

(Escherichia
coli) 		PF00480
(ROK) 		4 SER A 288
GLY A 317
ILE A 274
ALA A 269
 None
 0.94A 3aodA-1z6rA:
undetectable		 3aodA-1z6rA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zva E2 GLYCOPROTEIN

(Severe acute
respiratory
syndrome-related
coronavirus) 		PF01601
(Corona_S2) 		4 PHE A  27
ASN A  49
ILE A  48
ALA A  29
 None
 0.94A 3aodA-1zvaA:
2.3		 3aodA-1zvaA:
6.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS

(Escherichia
coli) 		PF05307
(Bundlin) 		4 SER A  34
GLY A 108
ILE A 119
ALA A 130
 None
 0.86A 3aodA-1zwtA:
undetectable		 3aodA-1zwtA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2asu HEPATOCYTE GROWTH
FACTOR-LIKE PROTEIN

(Homo sapiens) 		PF00089
(Trypsin) 		4 GLY B 509
ILE B 678
ALA B 520
PHE B 694
 None
 0.86A 3aodA-2asuB:
undetectable		 3aodA-2asuB:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2axc COLICIN E7

(Escherichia
coli) 		PF03515
(Cloacin) 		4 SER A 108
GLY A 248
GLU A 245
ILE A 129
 None
 0.86A 3aodA-2axcA:
undetectable		 3aodA-2axcA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bco SUCCINYLGLUTAMATE
DESUCCINYLASE

(Vibrio
parahaemolyticus) 		PF04952
(AstE_AspA) 		4 GLU A 110
ASN A 111
ILE A  62
ALA A  96
 None
 0.70A 3aodA-2bcoA:
undetectable		 3aodA-2bcoA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d7s RNA-DEPENDENT RNA
POLYMERASE

(Foot-and-mouth
disease virus) 		PF00680
(RdRP_1) 		4 PHE A 199
GLY A 197
GLU A 100
ALA A 302
 None
 0.93A 3aodA-2d7sA:
1.8		 3aodA-2d7sA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ftp HYDROXYMETHYLGLUTARY
L-COA LYASE

(Pseudomonas
aeruginosa) 		PF00682
(HMGL-like) 		4 SER A 233
GLY A 245
GLU A  21
ASN A  20
 None
 0.90A 3aodA-2ftpA:
undetectable		 3aodA-2ftpA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fxf DIAMINE
ACETYLTRANSFERASE 1

(Homo sapiens) 		PF00583
(Acetyltransf_1) 		4 SER A 136
GLY A  73
ILE A 105
PHE A 103
 ACO  A1000 (-2.6A)
None
ACO  A1000 (-4.2A)
None
 0.95A 3aodA-2fxfA:
undetectable		 3aodA-2fxfA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g4s NEXT TO BRCA1 GENE 1
PROTEIN

(Homo sapiens) 		PF00564
(PB1) 		4 GLY A  62
ASN A  59
ILE A  58
ALA A  67
 None
 0.96A 3aodA-2g4sA:
undetectable		 3aodA-2g4sA:
6.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ha9 UPF0210 PROTEIN
SP0239

(Streptococcus
pneumoniae) 		PF05167
(DUF711) 		5 GLY A 155
ASN A 157
ILE A 149
ALA A 383
PHE A 185
 None
 1.40A 3aodA-2ha9A:
undetectable		 3aodA-2ha9A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i7t CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
73 KDA SUBUNIT

(Homo sapiens) 		PF00753
(Lactamase_B)
PF07521
(RMMBL)
PF10996
(Beta-Casp) 		4 GLY A 208
GLU A 420
ASN A 422
ALA A 430
 None
 0.82A 3aodA-2i7tA:
undetectable		 3aodA-2i7tA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i9k MODIFICATION
METHYLASE HHAI

(Haemophilus
haemolyticus) 		PF00145
(DNA_methylase) 		4 PHE A  24
GLY A  22
ILE A 308
ALA A  27
 SAH  A 328 (-4.8A)
None
None
None
 0.89A 3aodA-2i9kA:
undetectable		 3aodA-2i9kA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i9k MODIFICATION
METHYLASE HHAI

(Haemophilus
haemolyticus) 		PF00145
(DNA_methylase) 		4 SER A 146
GLY A 319
ILE A  74
ALA A  33
 None
 0.82A 3aodA-2i9kA:
undetectable		 3aodA-2i9kA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j3m PROLYL-TRNA
SYNTHETASE

(Enterococcus
faecalis) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon)
PF04073
(tRNA_edit) 		5 SER A 207
GLY A 444
ILE A 408
ALA A 451
PHE A 192
 None
ATP  A 701 (-3.3A)
None
None
None
 1.49A 3aodA-2j3mA:
1.6		 3aodA-2j3mA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j7c BETA-GLUCOSIDASE A

(Thermotoga
maritima) 		PF00232
(Glyco_hydro_1) 		4 GLY A 394
GLU A 346
ILE A 386
ALA A 382
 None
 0.94A 3aodA-2j7cA:
undetectable		 3aodA-2j7cA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jgr YEGS

(Escherichia
coli) 		PF00781
(DAGK_cat) 		4 GLY A  66
GLU A  72
ILE A  90
ALA A 100
 POP  A1300 (-3.5A)
None
None
None
 0.95A 3aodA-2jgrA:
undetectable		 3aodA-2jgrA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jza NITRITE REDUCTASE
[NAD(P)H] SMALL
SUBUNIT

(Pectobacterium
atrosepticum) 		PF13806
(Rieske_2) 		4 SER A 111
PHE A  77
GLY A  82
ILE A  42
 None
 0.87A 3aodA-2jzaA:
undetectable		 3aodA-2jzaA:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k9k TONB2

(Vibrio
anguillarum) 		PF03544
(TonB_C) 		4 PHE A 202
GLY A 140
ILE A 204
ALA A 133
 None
 0.93A 3aodA-2k9kA:
undetectable		 3aodA-2k9kA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lcq PUTATIVE TOXIN VAPC6

(Pyrococcus
horikoshii) 		PF17146
(PIN_6) 		4 SER A  13
GLU A  84
ILE A 106
ALA A  69
 None
 0.95A 3aodA-2lcqA:
undetectable		 3aodA-2lcqA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ljr GLUTATHIONE
S-TRANSFERASE

(Homo sapiens) 		PF00043
(GST_C)
PF02798
(GST_N) 		5 PHE A 200
GLY A 202
GLU A 204
ILE A  19
PHE A  20
 None
 1.00A 3aodA-2ljrA:
undetectable		 3aodA-2ljrA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lxj COLD SHOCK-LIKE
PROTEIN CSPLA

(Listeria
monocytogenes) 		PF00313
(CSD) 		4 PHE A  15
GLY A  16
GLU A  43
ILE A  33
 None
 0.86A 3aodA-2lxjA:
undetectable		 3aodA-2lxjA:
5.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lxj COLD SHOCK-LIKE
PROTEIN CSPLA

(Listeria
monocytogenes) 		PF00313
(CSD) 		4 PHE A  27
GLU A  43
ALA A  60
PHE A  30
 None
 0.96A 3aodA-2lxjA:
undetectable		 3aodA-2lxjA:
5.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1v ENDOPLASMIN

(Canis lupus) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		4 GLY A 244
ASN A 216
ILE A 115
ALA A 111
 None
None
None
ADP  A 301 (-3.4A)
 0.95A 3aodA-2o1vA:
undetectable		 3aodA-2o1vA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1w ENDOPLASMIN

(Canis lupus) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		4 GLY A 244
ASN A 216
ILE A 115
ALA A 111
 None
 0.97A 3aodA-2o1wA:
undetectable		 3aodA-2o1wA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2obp PUTATIVE DNA-BINDING
PROTEIN

(Cupriavidus
pinatubonensis) 		no annotation 4 GLY A  28
GLU A  30
ASN A  31
ALA A  84
 None
 0.87A 3aodA-2obpA:
undetectable		 3aodA-2obpA:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pg8 DPGC

(Streptomyces
toyocaensis) 		PF00378
(ECH_1) 		4 SER A 342
PHE A 405
ALA A 407
PHE A 412
 None
 0.89A 3aodA-2pg8A:
undetectable		 3aodA-2pg8A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qe7 ATP SYNTHASE SUBUNIT
BETA

(Bacillus sp.
TA2.A1) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 GLY D 151
GLU D 325
ASN D 323
ALA D 298
 None
 0.93A 3aodA-2qe7D:
undetectable		 3aodA-2qe7D:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qgh DIAMINOPIMELATE
DECARBOXYLASE

(Helicobacter
pylori) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		5 SER A 181
GLY A  63
ILE A  85
ALA A  75
PHE A  87
 None
 1.40A 3aodA-2qghA:
undetectable		 3aodA-2qghA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qor GUANYLATE KINASE

(Plasmodium
vivax) 		PF00625
(Guanylate_kin) 		4 SER A  37
GLY A  11
ASN A 103
ALA A 161
 5GP  A 197 (-2.5A)
None
5GP  A 197 (-3.5A)
None
 0.95A 3aodA-2qorA:
undetectable		 3aodA-2qorA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r3u PROTEASE DEGS

(Escherichia
coli) 		PF13365
(Trypsin_2) 		4 GLY A  82
ASN A  94
ILE A 215
ALA A 204
 None
 0.94A 3aodA-2r3uA:
undetectable		 3aodA-2r3uA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uxt PROTEIN SUFI

(Escherichia
coli) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 PHE A 207
GLY A 206
GLU A 392
ALA A 150
 None
 0.69A 3aodA-2uxtA:
undetectable		 3aodA-2uxtA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uz0 TRIBUTYRIN ESTERASE

(Streptococcus
pneumoniae) 		PF00756
(Esterase) 		4 PHE A 127
GLY A 125
ILE A 116
ALA A 130
 None
 0.84A 3aodA-2uz0A:
undetectable		 3aodA-2uz0A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v28 PHENYLALANINE-4-HYDR
OXYLASE

(Colwellia
psychrerythraea) 		PF00351
(Biopterin_H) 		4 PHE A 168
GLY A 169
ILE A 179
ALA A 194
 None
 0.90A 3aodA-2v28A:
undetectable		 3aodA-2v28A:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v7y CHAPERONE PROTEIN
DNAK

(Geobacillus
kaustophilus) 		PF00012
(HSP70) 		4 SER A   2
GLY A 132
GLU A 138
ILE A   7
 None
 0.88A 3aodA-2v7yA:
undetectable		 3aodA-2v7yA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ve3 PUTATIVE CYTOCHROME
P450 120

(Synechocystis
sp. PCC 6803) 		PF00067
(p450) 		4 PHE A 384
GLY A 385
ASN A  65
ILE A 346
 HEM  A1444 (-4.5A)
HEM  A1444 (-4.0A)
None
None
 0.93A 3aodA-2ve3A:
2.8		 3aodA-2ve3A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpi GMP SYNTHASE

(Homo sapiens) 		PF00117
(GATase) 		5 SER A 138
PHE A 114
GLY A 163
ILE A 177
ALA A 161
 None
 1.44A 3aodA-2vpiA:
undetectable		 3aodA-2vpiA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vsa MOSQUITOCIDAL TOXIN

(Lysinibacillus
sphaericus) 		PF05588
(Botulinum_HA-17)
PF14200
(RicinB_lectin_2) 		4 SER A 233
GLY A  85
GLU A 534
ILE A  87
 None
 0.92A 3aodA-2vsaA:
undetectable		 3aodA-2vsaA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w8q SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00171
(Aldedh) 		4 SER A 304
GLY A 216
ILE A 521
ALA A 171
 None
 0.97A 3aodA-2w8qA:
1.5		 3aodA-2w8qA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wtb FATTY ACID
MULTIFUNCTIONAL
PROTEIN (ATMFP2)

(Arabidopsis
thaliana) 		PF00378
(ECH_1)
PF00725
(3HCDH)
PF02737
(3HCDH_N) 		4 PHE A 450
GLY A 326
ILE A 317
ALA A 398
 None
 0.95A 3aodA-2wtbA:
undetectable		 3aodA-2wtbA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xcm CYTOSOLIC HEAT SHOCK
PROTEIN 90

(Hordeum vulgare) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		4 GLY A 172
ASN A 143
ILE A  47
ALA A  43
 None
None
None
ADP  A1211 (-3.2A)
 0.97A 3aodA-2xcmA:
undetectable		 3aodA-2xcmA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xh1 KYNURENINE/ALPHA-AMI
NOADIPATE
AMINOTRANSFERASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00155
(Aminotran_1_2) 		5 SER A  11
GLY A 120
GLU A 126
ILE A 256
ALA A 258
 None
 1.32A 3aodA-2xh1A:
undetectable		 3aodA-2xh1A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xry DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE

(Methanosarcina
mazei) 		PF00875
(DNA_photolyase) 		4 SER A 389
GLY A 321
GLU A 393
ILE A 400
 None
 0.84A 3aodA-2xryA:
undetectable		 3aodA-2xryA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yqh UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE

(Candida
albicans) 		PF01704
(UDPGP) 		4 PHE A 362
GLU A 309
ILE A 364
ALA A  56
 None
GN1  A1001 (-3.0A)
None
None
 0.76A 3aodA-2yqhA:
undetectable		 3aodA-2yqhA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yuj UBIQUITIN FUSION
DEGRADATION 1-LIKE

(Homo sapiens) 		PF03152
(UFD1) 		4 SER A 178
PHE A  16
ASN A 113
ILE A  58
 None
 0.95A 3aodA-2yujA:
undetectable		 3aodA-2yujA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z0f PUTATIVE
PHOSPHOGLUCOMUTASE

(Thermus
thermophilus) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 SER A 108
GLY A 382
ALA A 323
PHE A 367
 None
 0.96A 3aodA-2z0fA:
undetectable		 3aodA-2z0fA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zuy YESX PROTEIN

(Bacillus
subtilis) 		PF01839
(FG-GAP) 		4 GLY A 403
GLU A 383
ILE A 346
ALA A 351
 None
CA  A 625 (-2.3A)
None
None
 0.95A 3aodA-2zuyA:
undetectable		 3aodA-2zuyA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zy2 L-ASPARTATE
4-CARBOXYLYASE

(Pseudomonas sp.
ATCC 19121) 		PF00155
(Aminotran_1_2) 		5 SER A 499
PHE A 317
GLY A 318
ASN A  41
ALA A  44
 None
 1.28A 3aodA-2zy2A:
2.4		 3aodA-2zy2A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3adc L-SERYL-TRNA(SEC)
KINASE

(Methanocaldococcus
jannaschii) 		PF08433
(KTI12) 		4 GLY A 136
GLU A 134
ILE A  99
PHE A 145
 None
 0.89A 3aodA-3adcA:
undetectable		 3aodA-3adcA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bhi CARBONYL REDUCTASE
[NADPH] 1

(Homo sapiens) 		PF00106
(adh_short) 		4 SER A 204
GLY A  91
ASN A  88
PHE A 115
 None
NAP  A 309 (-4.0A)
None
None
 0.92A 3aodA-3bhiA:
undetectable		 3aodA-3bhiA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3brs PERIPLASMIC BINDING
PROTEIN/LACI
TRANSCRIPTIONAL
REGULATOR

(Lachnoclostridium
phytofermentans) 		PF13407
(Peripla_BP_4) 		4 SER A 143
GLY A 196
ASN A 198
ALA A 205
 None
 0.84A 3aodA-3brsA:
undetectable		 3aodA-3brsA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bwn L-TRYPTOPHAN
AMINOTRANSFERASE

(Arabidopsis
thaliana) 		PF04864
(Alliinase_C) 		4 SER A  60
PHE A 215
GLY A 227
ILE A  77
 None
 0.78A 3aodA-3bwnA:
undetectable		 3aodA-3bwnA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c07 PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Streptomyces
coelicolor) 		PF00440
(TetR_N) 		4 PHE A  60
GLY A  62
ILE A  45
ALA A  56
 None
 0.92A 3aodA-3c07A:
undetectable		 3aodA-3c07A:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ce6 ADENOSYLHOMOCYSTEINA
SE

(Mycobacterium
tuberculosis) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		4 GLY A 282
GLU A 367
ASN A 340
ILE A 306
 NAD  A 550 ( 3.7A)
None
NAD  A 550 (-3.9A)
NAD  A 550 (-4.0A)
 0.96A 3aodA-3ce6A:
undetectable		 3aodA-3ce6A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ct9 ACETYLORNITHINE
DEACETYLASE

(Bacteroides
thetaiotaomicron) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 SER A 133
GLY A 320
GLU A 161
ILE A 158
 None
 0.93A 3aodA-3ct9A:
6.3		 3aodA-3ct9A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3czx PUTATIVE
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE

(Neisseria
meningitidis) 		PF01520
(Amidase_3) 		4 PHE A 122
GLU A 175
ILE A 141
ALA A  91
 None
 0.90A 3aodA-3czxA:
undetectable		 3aodA-3czxA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY

(Corynebacterium
glutamicum) 		PF10727
(Rossmann-like) 		4 SER A  88
GLY A  55
ILE A  48
ALA A  50
 None
 0.92A 3aodA-3dfuA:
undetectable		 3aodA-3dfuA:
12.31