SIMILAR PATTERNS OF AMINO ACIDS FOR 3AIA_A_SAMA206_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ac5 KEX1(DELTA)P

(Saccharomyces
cerevisiae) 		PF00450
(Peptidase_S10) 		4 LEU A 100
GLY A  98
LEU A  17
SER A  18
 None
 0.82A 3aiaA-1ac5A:
1.7		 3aiaA-1ac5A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e2t N-HYDROXYARYLAMINE
O-ACETYLTRANSFERASE

(Salmonella
enterica) 		PF00797
(Acetyltransf_2) 		4 LEU A 246
GLY A 251
LEU A 242
SER A 241
 None
 0.92A 3aiaA-1e2tA:
undetectable		 3aiaA-1e2tA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gq2 MALIC ENZYME

(Columba livia) 		PF00390
(malic)
PF03949
(Malic_M) 		4 LEU A  95
GLY A  37
LEU A  88
SER A  87
 None
 0.94A 3aiaA-1gq2A:
2.1		 3aiaA-1gq2A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hcy ARTHROPODAN
HEMOCYANIN

(Panulirus
interruptus) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 LEU A 553
GLY A   6
LEU A 555
SER A 556
 None
 0.83A 3aiaA-1hcyA:
undetectable		 3aiaA-1hcyA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m46 MYOSIN LIGHT CHAIN

(Saccharomyces
cerevisiae) 		PF13499
(EF-hand_7) 		4 LEU A  31
GLY A  35
LEU A  27
SER A  26
 None
 0.93A 3aiaA-1m46A:
undetectable		 3aiaA-1m46A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ns5 HYPOTHETICAL PROTEIN
YBEA

(Escherichia
coli) 		PF02590
(SPOUT_MTase) 		4 LEU A  72
GLY A 103
LEU A 122
SER A 123
 None
 0.52A 3aiaA-1ns5A:
7.1		 3aiaA-1ns5A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE

(Xenopus laevis) 		no annotation 4 LEU A 236
GLY A 240
LEU A 209
CYH A 210
 None
 0.82A 3aiaA-1oe5A:
1.6		 3aiaA-1oe5A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1otk PHENYLACETIC ACID
DEGRADATION PROTEIN
PAAC

(Escherichia
coli) 		PF05138
(PaaA_PaaC) 		4 LEU A  39
GLY A  28
LEU A  23
SER A  20
 None
 0.97A 3aiaA-1otkA:
undetectable		 3aiaA-1otkA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgr PROTEIN (G-CSF
RECEPTOR)

(Mus musculus) 		no annotation 4 LEU B 187
GLY B 206
LEU B 133
SER B 134
 None
 0.64A 3aiaA-1pgrB:
undetectable		 3aiaA-1pgrB:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qxn SULFIDE
DEHYDROGENASE

(Wolinella
succinogenes) 		PF00581
(Rhodanese) 		4 LEU A  74
GLY A  78
LEU A  70
SER A  66
 None
 0.86A 3aiaA-1qxnA:
undetectable		 3aiaA-1qxnA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r20 ULTRASPIRACLE
PROTEIN

(Heliothis
virescens) 		PF00104
(Hormone_recep) 		4 LEU A 325
GLY A 328
LEU A 249
SER A 248
 None
None
EPH  A4000 (-4.4A)
None
 0.92A 3aiaA-1r20A:
undetectable		 3aiaA-1r20A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r76 PECTATE LYASE

(Niveispirillum
irakense) 		PF09492
(Pec_lyase) 		4 LEU A 290
GLY A 342
LEU A 314
SER A 315
 None
 0.96A 3aiaA-1r76A:
undetectable		 3aiaA-1r76A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sml PROTEIN
(PENICILLINASE)

(Stenotrophomonas
maltophilia) 		PF00753
(Lactamase_B) 		4 LEU A 114
GLY A 118
LEU A  82
SER A  83
 None
 0.79A 3aiaA-1smlA:
undetectable		 3aiaA-1smlA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ta3 ENDO-1,4-BETA-XYLANA
SE

(Aspergillus
nidulans) 		PF00331
(Glyco_hydro_10) 		4 LEU B 282
GLY B 267
LEU B   3
SER B   2
 None
 0.94A 3aiaA-1ta3B:
undetectable		 3aiaA-1ta3B:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1th8 ANTI-SIGMA F FACTOR
ANTAGONIST

(Geobacillus
stearothermophilus) 		PF01740
(STAS) 		4 LEU B  18
GLY B  51
LEU B   3
SER B   2
 None
 0.68A 3aiaA-1th8B:
undetectable		 3aiaA-1th8B:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT

(Rattus
norvegicus) 		PF00432
(Prenyltrans) 		4 LEU B 344
LEU B 232
SER B 229
CYH B 180
 None
 0.87A 3aiaA-1tnuB:
undetectable		 3aiaA-1tnuB:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1weh CONSERVED
HYPOTHETICAL PROTEIN
TT1887

(Thermus
thermophilus) 		PF03641
(Lysine_decarbox) 		4 LEU A  48
GLY A  43
LEU A  36
CYH A  38
 None
 0.84A 3aiaA-1wehA:
2.9		 3aiaA-1wehA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xho CHORISMATE MUTASE

(Ruminiclostridium
thermocellum) 		PF07736
(CM_1) 		4 GLY A   7
LEU A  83
SER A  82
CYH A  86
 None
 0.62A 3aiaA-1xhoA:
undetectable		 3aiaA-1xhoA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xnt PROTEIN (DNA-REPAIR
PROTEIN XRCC1)

(Homo sapiens) 		PF01834
(XRCC1_N) 		4 LEU A 144
GLY A  64
SER A  14
CYH A 132
 None
 0.79A 3aiaA-1xntA:
undetectable		 3aiaA-1xntA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bi7 UDP-GALACTOPYRANOSE
MUTASE

(Klebsiella
pneumoniae) 		PF03275
(GLF)
PF13450
(NAD_binding_8) 		4 LEU A 325
GLY A 320
LEU A 329
SER A 330
 None
 0.94A 3aiaA-2bi7A:
1.2		 3aiaA-2bi7A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN

(Bulinus
truncatus) 		PF02931
(Neur_chan_LBD) 		4 LEU A   7
GLY A  12
LEU A  64
SER A  63
 None
 0.83A 3aiaA-2bj0A:
undetectable		 3aiaA-2bj0A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ef4 ARGINASE

(Thermus
thermophilus) 		PF00491
(Arginase) 		4 LEU A 261
GLY A  94
LEU A 259
SER A 258
 None
 0.74A 3aiaA-2ef4A:
undetectable		 3aiaA-2ef4A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ell ACIDIC LEUCINE-RICH
NUCLEAR
PHOSPHOPROTEIN 32
FAMILY MEMBER B

(Homo sapiens) 		PF14580
(LRR_9) 		4 LEU A 127
GLY A 104
LEU A 125
SER A 124
 None
 0.93A 3aiaA-2ellA:
undetectable		 3aiaA-2ellA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ho5 OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY

(Streptococcus
pneumoniae) 		PF01408
(GFO_IDH_MocA) 		4 LEU A 209
GLY A 227
LEU A 203
SER A 206
 None
 0.87A 3aiaA-2ho5A:
2.0		 3aiaA-2ho5A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ixl DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE

(Streptococcus
suis) 		PF00908
(dTDP_sugar_isom) 		4 LEU A  93
GLY A 128
LEU A 132
SER A 133
 None
TRH  A1198 ( 4.1A)
None
None
 0.89A 3aiaA-2ixlA:
undetectable		 3aiaA-2ixlA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2je1 ACIDIC LEUCINE-RICH
NUCLEAR
PHOSPHOPROTEIN 32
FAMILY MEMBER A

(Homo sapiens) 		PF14580
(LRR_9) 		4 LEU A 120
GLY A  97
LEU A 118
SER A 117
 None
 0.87A 3aiaA-2je1A:
undetectable		 3aiaA-2je1A:
25.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nzt HEXOKINASE-2

(Homo sapiens) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		4 LEU A 833
GLY A 837
LEU A 479
SER A 480
 None
 0.84A 3aiaA-2nztA:
undetectable		 3aiaA-2nztA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o2z HYPOTHETICAL PROTEIN

(Bacillus
halodurans) 		PF01933
(UPF0052) 		4 LEU A  19
GLY A  14
LEU A  64
SER A  65
 None
NAD  A 400 ( 3.2A)
None
None
 0.79A 3aiaA-2o2zA:
2.2		 3aiaA-2o2zA:
22.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus) 		PF04013
(Methyltrn_RNA_2) 		5 LEU A 221
GLY A 242
LEU A 265
SER A 266
CYH A 275
 SAM  A 301 (-4.3A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.4A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.1A)
 0.33A 3aiaA-2qmmA:
31.8		 3aiaA-2qmmA:
44.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9t SLIT HOMOLOG 2
PROTEIN N-PRODUCT

(Homo sapiens) 		PF01462
(LRRNT)
PF01463
(LRRCT)
PF13855
(LRR_8) 		4 LEU B 355
GLY B 357
LEU B 353
SER B 352
 None
 0.77A 3aiaA-2v9tB:
undetectable		 3aiaA-2v9tB:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x50 TRYPANOTHIONE
REDUCTASE

(Leishmania
infantum) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LEU A 242
GLY A 246
LEU A 238
SER A 237
 None
 0.85A 3aiaA-2x50A:
undetectable		 3aiaA-2x50A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x77 ADP-RIBOSYLATION
FACTOR

(Leishmania
major) 		PF00025
(Arf) 		4 LEU A  40
GLY A  43
LEU A   8
SER A   7
 None
 0.73A 3aiaA-2x77A:
undetectable		 3aiaA-2x77A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsk CSGC

(Escherichia
coli) 		PF10610
(Tafi-CsgC) 		4 LEU A  89
GLY A  86
LEU A  91
SER A  92
 None
ACT  A1098 ( 3.8A)
None
None
 0.93A 3aiaA-2xskA:
undetectable		 3aiaA-2xskA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yvl HYPOTHETICAL PROTEIN

(Aquifex
aeolicus) 		PF08704
(GCD14) 		4 LEU A 105
GLY A 101
LEU A 109
SER A 110
 SAM  A 601 (-4.6A)
SAM  A 601 (-3.5A)
None
None
 0.93A 3aiaA-2yvlA:
undetectable		 3aiaA-2yvlA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zuk ALPHA-AMINO-EPSILON-
CAPROLACTAM RACEMASE

(Achromobacter
obae) 		PF00202
(Aminotran_3) 		4 LEU A 329
GLY A 350
LEU A 333
SER A 334
 None
 0.82A 3aiaA-2zukA:
undetectable		 3aiaA-2zukA:
20.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ai9 UPF0217 PROTEIN
MJ1640

(Methanocaldococcus
jannaschii) 		PF04013
(Methyltrn_RNA_2) 		6 LEU X 136
MET X 138
GLY X 156
LEU X 179
SER X 180
CYH X 189
 SAM  X 501 (-4.3A)
SAM  X 501 (-4.8A)
SAM  X 501 (-3.2A)
SAM  X 501 (-4.4A)
SAM  X 501 (-4.2A)
SAM  X 501 (-3.3A)
 0.36A 3aiaA-3ai9X:
37.9		 3aiaA-3ai9X:
98.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqs BACTERIAL REGULATORY
PROTEINS, TETR
FAMILY

(Corynebacterium
glutamicum) 		PF00440
(TetR_N) 		4 LEU A 114
GLY A 109
LEU A 175
SER A 174
 None
 0.96A 3aiaA-3aqsA:
undetectable		 3aiaA-3aqsA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN

(Chromobacterium
violaceum) 		PF03536
(VRP3) 		4 LEU A 187
GLY A 191
LEU A 121
SER A 122
 None
 0.74A 3aiaA-3bo6A:
undetectable		 3aiaA-3bo6A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3l ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE

(Homo sapiens) 		PF00305
(Lipoxygenase) 		4 GLY A 477
LEU A 525
SER A 521
CYH A 526
 None
 0.75A 3aiaA-3d3lA:
undetectable		 3aiaA-3d3lA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fms TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY

(Thermotoga
maritima) 		PF00392
(GntR)
PF07729
(FCD) 		4 LEU A  32
GLY A  68
LEU A  37
SER A  38
 None
ACT  A 303 ( 3.8A)
None
None
 0.66A 3aiaA-3fmsA:
undetectable		 3aiaA-3fmsA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila) 		no annotation 4 LEU A  58
GLY A  60
LEU A  56
SER A  55
 None
 0.80A 3aiaA-3gozA:
undetectable		 3aiaA-3gozA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila) 		no annotation 4 LEU A  87
GLY A  60
LEU A  85
SER A  84
 None
 0.96A 3aiaA-3gozA:
undetectable		 3aiaA-3gozA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila) 		no annotation 4 LEU A  87
GLY A  89
LEU A  85
SER A  84
 None
 0.71A 3aiaA-3gozA:
undetectable		 3aiaA-3gozA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila) 		no annotation 4 LEU A 145
GLY A 147
LEU A 143
SER A 142
 None
 0.80A 3aiaA-3gozA:
undetectable		 3aiaA-3gozA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila) 		no annotation 4 LEU A 174
GLY A 176
LEU A 172
SER A 171
 None
 0.80A 3aiaA-3gozA:
undetectable		 3aiaA-3gozA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h39 TRNA NUCLEOTIDYL
TRANSFERASE-RELATED
PROTEIN

(Thermotoga
maritima) 		PF01743
(PolyA_pol)
PF12627
(PolyA_pol_RNAbd) 		4 LEU A  92
GLY A  94
LEU A  90
SER A  89
 None
 0.78A 3aiaA-3h39A:
undetectable		 3aiaA-3h39A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ho8 PYRUVATE CARBOXYLASE

(Staphylococcus
aureus) 		PF00289
(Biotin_carb_N)
PF00682
(HMGL-like)
PF02436
(PYC_OADA)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 LEU A 817
GLY A 819
LEU A 813
SER A 812
 None
 0.90A 3aiaA-3ho8A:
2.7		 3aiaA-3ho8A:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9v NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 3

(Thermus
thermophilus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4)
PF10588
(NADH-G_4Fe-4S_3)
PF13510
(Fer2_4) 		4 LEU 3 176
GLY 3 233
LEU 3 170
SER 3 171
 None
SF4  3 784 (-4.2A)
None
None
 0.65A 3aiaA-3i9v3:
undetectable		 3aiaA-3i9v3:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j0a TOLL-LIKE RECEPTOR 5

(Homo sapiens) 		PF01582
(TIR)
PF13855
(LRR_8) 		4 LEU A 260
GLY A 235
LEU A 258
SER A 257
 None
 0.95A 3aiaA-3j0aA:
undetectable		 3aiaA-3j0aA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kd4 PUTATIVE PROTEASE

(Parabacteroides
distasonis) 		PF12969
(DUF3857)
PF12970
(DUF3858) 		4 LEU A 239
GLY A 342
LEU A 379
SER A 380
 None
 0.93A 3aiaA-3kd4A:
undetectable		 3aiaA-3kd4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kos HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR

(Citrobacter
freundii) 		PF03466
(LysR_substrate) 		4 LEU A 109
GLY A 107
LEU A 113
SER A 114
 None
 0.89A 3aiaA-3kosA:
undetectable		 3aiaA-3kosA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3osv FLAGELLAR BASAL-BODY
ROD MODIFICATION
PROTEIN FLGD

(Pseudomonas
aeruginosa) 		PF13860
(FlgD_ig)
PF13861
(FLgD_tudor) 		4 LEU A 119
GLY A 125
LEU A 129
SER A 130
 None
 0.90A 3aiaA-3osvA:
undetectable		 3aiaA-3osvA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p9z UROPORPHYRINOGEN III
COSYNTHASE (HEMD)

(Helicobacter
pylori) 		PF02602
(HEM4) 		4 LEU A 126
GLY A 130
LEU A 122
SER A 121
 None
None
MLI  A 301 (-4.9A)
None
 0.93A 3aiaA-3p9zA:
undetectable		 3aiaA-3p9zA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE

(Sus scrofa) 		PF00305
(Lipoxygenase) 		4 GLY A 478
LEU A 526
SER A 522
CYH A 527
 None
 0.75A 3aiaA-3rdeA:
undetectable		 3aiaA-3rdeA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rg1 CD180 MOLECULE

(Bos taurus) 		PF00560
(LRR_1)
PF13855
(LRR_8) 		4 LEU A 252
GLY A 231
LEU A 250
SER A 249
 None
 0.86A 3aiaA-3rg1A:
undetectable		 3aiaA-3rg1A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s5p RIBOSE 5-PHOSPHATE
ISOMERASE

(Giardia
intestinalis) 		PF02502
(LacAB_rpiB) 		4 LEU A  14
MET A  16
GLY A  10
LEU A  18
 None
 0.95A 3aiaA-3s5pA:
3.2		 3aiaA-3s5pA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6q CD180 ANTIGEN

(Mus musculus) 		PF13855
(LRR_8) 		4 LEU A 206
GLY A 208
LEU A 204
SER A 203
 None
 0.91A 3aiaA-3t6qA:
undetectable		 3aiaA-3t6qA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tvi ASPARTOKINASE

(Clostridium
acetobutylicum) 		PF00696
(AA_kinase)
PF01842
(ACT) 		4 LEU A 274
GLY A 272
LEU A 276
SER A 230
 None
 0.91A 3aiaA-3tviA:
1.9		 3aiaA-3tviA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v44 TOLL-LIKE RECEPTOR
5B AND VARIABLE
LYMPHOCYTE RECEPTOR
B.61 CHIMERIC
PROTEIN

(Eptatretus
burgeri;
Danio rerio) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		4 LEU A 263
GLY A 238
LEU A 261
SER A 260
 None
 0.77A 3aiaA-3v44A:
undetectable		 3aiaA-3v44A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w5n PUTATIVE
RHAMNOSIDASE

(Streptomyces
avermitilis) 		PF05592
(Bac_rhamnosid)
PF08531
(Bac_rhamnosid_N)
PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C) 		4 LEU A 242
GLY A 247
LEU A 165
SER A 217
 None
 0.96A 3aiaA-3w5nA:
undetectable		 3aiaA-3w5nA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zvq LYSOZYME C
LYSOZYME C

(Gallus gallus;
Gallus gallus) 		PF00062
(Lys)
PF00062
(Lys) 		4 LEU B 129
GLY B 126
LEU A  25
SER A  24
 None
 0.90A 3aiaA-3zvqB:
undetectable		 3aiaA-3zvqB:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16739
(CARD_2) 		4 LEU A 173
GLY A 177
LEU A 169
SER A 168
 None
 0.96A 3aiaA-4a2qA:
undetectable		 3aiaA-4a2qA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2w RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16739
(CARD_2) 		4 LEU A 173
GLY A 177
LEU A 169
SER A 168
 None
 0.94A 3aiaA-4a2wA:
undetectable		 3aiaA-4a2wA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ars HISTIDINE ACID
PHOSPHATASE

(Hafnia alvei) 		PF00328
(His_Phos_2) 		4 LEU A 220
GLY A 215
LEU A 172
SER A 169
 None
 0.92A 3aiaA-4arsA:
undetectable		 3aiaA-4arsA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g3j STEROL
14-ALPHA-DEMETHYLASE

(Trypanosoma
brucei) 		PF00067
(p450) 		4 LEU A 262
GLY A 185
LEU A 266
SER A 267
 None
 0.93A 3aiaA-4g3jA:
undetectable		 3aiaA-4g3jA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gqb PROTEIN ARGININE
N-METHYLTRANSFERASE
5

(Homo sapiens) 		PF05185
(PRMT5)
PF17285
(PRMT5_TIM)
PF17286
(PRMT5_C) 		4 LEU A 559
GLY A 466
LEU A 565
SER A 566
 None
 0.94A 3aiaA-4gqbA:
undetectable		 3aiaA-4gqbA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h43 27.5 KDA VIRULENCE
PROTEIN

(Salmonella
enterica) 		PF03536
(VRP3) 		4 LEU A 187
GLY A 191
LEU A 121
SER A 122
 None
 0.86A 3aiaA-4h43A:
undetectable		 3aiaA-4h43A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hxq ARGINASE-1

(Homo sapiens) 		PF00491
(Arginase) 		4 LEU A  97
GLY A  99
LEU A  95
SER A  94
 None
 0.62A 3aiaA-4hxqA:
undetectable		 3aiaA-4hxqA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iv9 TRYPTOPHAN
2-MONOOXYGENASE

(Pseudomonas
savastanoi) 		PF01593
(Amino_oxidase) 		4 LEU A 548
LEU A 542
SER A 543
CYH A 532
 None
 0.83A 3aiaA-4iv9A:
2.0		 3aiaA-4iv9A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana) 		PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 LEU A  93
GLY A  91
LEU A 132
SER A 133
 None
None
None
NAG  A 811 (-3.4A)
 0.90A 3aiaA-4j0mA:
undetectable		 3aiaA-4j0mA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jcl CYCLOMALTODEXTRIN
GLUCANOTRANSFERASE

(Paenibacillus
macerans) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG) 		4 LEU A 607
GLY A 624
LEU A 614
SER A 616
 None
 0.86A 3aiaA-4jclA:
undetectable		 3aiaA-4jclA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A

(Mus musculus) 		PF13516
(LRR_6) 		4 LEU A 461
GLY A 433
LEU A 459
SER A 458
 None
 0.75A 3aiaA-4k17A:
undetectable		 3aiaA-4k17A:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nrd UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF16255
(Lipase_GDSL_lke) 		4 LEU A 171
GLY A  30
LEU A 198
SER A 174
 None
 0.88A 3aiaA-4nrdA:
undetectable		 3aiaA-4nrdA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfq HYPOXANTHINE
PHOSPHORIBOSYLTRANSF
ERASE

(Brachybacterium
faecium) 		PF00156
(Pribosyltran) 		4 LEU A 135
GLY A 132
LEU A 139
SER A 140
 None
 0.64A 3aiaA-4pfqA:
undetectable		 3aiaA-4pfqA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiq D-XYLOSE-PROTON
SYMPORTER

(Escherichia
coli) 		PF00083
(Sugar_tr) 		4 LEU A  56
GLY A  58
LEU A  48
SER A  49
 None
 0.96A 3aiaA-4qiqA:
undetectable		 3aiaA-4qiqA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiq D-XYLOSE-PROTON
SYMPORTER

(Escherichia
coli) 		PF00083
(Sugar_tr) 		4 LEU A 142
GLY A 137
LEU A 146
SER A 147
 None
 0.92A 3aiaA-4qiqA:
undetectable		 3aiaA-4qiqA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u7l LEUCINE-RICH REPEATS
AND
IMMUNOGLOBULIN-LIKE
DOMAINS PROTEIN 1

(Homo sapiens) 		PF01463
(LRRCT)
PF13855
(LRR_8) 		4 LEU A  35
GLY A  16
LEU A  33
SER A  32
 None
NAG  A 501 (-3.8A)
None
None
 0.86A 3aiaA-4u7lA:
undetectable		 3aiaA-4u7lA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd1 ACETOACETATE-COA
LIGASE

(Streptomyces
lividans) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
PF16177
(ACAS_N) 		4 LEU A 138
GLY A 142
LEU A 134
SER A 133
 None
 0.94A 3aiaA-4wd1A:
undetectable		 3aiaA-4wd1A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wg1 LYSOZYME C

(Gallus gallus) 		PF00062
(Lys) 		4 LEU A 129
GLY A 126
LEU A  25
SER A  24
 None
 0.89A 3aiaA-4wg1A:
undetectable		 3aiaA-4wg1A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wh3 N-ACETYLHEXOSAMINE
1-KINASE

(Bifidobacterium
longum) 		PF01636
(APH) 		4 LEU A  72
GLY A  76
LEU A 134
SER A 135
 None
 0.93A 3aiaA-4wh3A:
undetectable		 3aiaA-4wh3A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ypo KETOL-ACID
REDUCTOISOMERASE

(Mycobacterium
tuberculosis) 		PF01450
(IlvC)
PF07991
(IlvN) 		4 LEU A 159
GLY A 156
LEU A 163
SER A 164
 None
 0.88A 3aiaA-4ypoA:
undetectable		 3aiaA-4ypoA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z0c TOLL-LIKE RECEPTOR
13

(Mus musculus) 		PF00560
(LRR_1)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 LEU A 301
GLY A 303
LEU A 299
SER A 298
 None
None
None
NAG  A 906 (-2.3A)
 0.79A 3aiaA-4z0cA:
undetectable		 3aiaA-4z0cA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z80 CYTOADHERENCE-LINKED
ASEXUAL PROTEIN

(Toxoplasma
gondii) 		no annotation 4 LEU C1304
GLY C1306
LEU C1300
SER C1299
 None
 0.96A 3aiaA-4z80C:
undetectable		 3aiaA-4z80C:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ah0 LIPASE

(Pelosinus
fermentans) 		no annotation 4 LEU A 211
GLY A 206
LEU A 230
SER A 229
 None
 0.77A 3aiaA-5ah0A:
undetectable		 3aiaA-5ah0A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b2o CRISPR-ASSOCIATED
ENDONUCLEASE CAS9

(Francisella
tularensis) 		no annotation 4 GLY A 398
LEU A 420
SER A 416
CYH A 421
 EDO  A1719 (-3.6A)
None
None
None
 0.67A 3aiaA-5b2oA:
undetectable		 3aiaA-5b2oA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5erb POLYKETIDE SYNTHASE

(Bacillus
amyloliquefaciens) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		4 LEU A 271
GLY A 274
LEU A 258
SER A 259
 None
 0.94A 3aiaA-5erbA:
undetectable		 3aiaA-5erbA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5et1 ESPIN

(Mus musculus) 		PF12796
(Ank_2)
PF13637
(Ank_4)
PF13857
(Ank_5) 		4 LEU A  90
GLY A  94
LEU A  86
SER A  84
 None
 0.89A 3aiaA-5et1A:
undetectable		 3aiaA-5et1A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fl3 PILI RETRACTION
PROTEIN PILT

(Thermus
thermophilus) 		PF00437
(T2SSE) 		4 LEU A 233
GLY A 231
LEU A 235
SER A 236
 None
 0.93A 3aiaA-5fl3A:
undetectable		 3aiaA-5fl3A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikf CHROMATIN REMODELING
FACTOR MIT1

(Schizosaccharomyces
pombe) 		no annotation 4 LEU A1335
GLY A1337
LEU A1350
CYH A1347
 ZN  A1502 ( 4.8A)
None
None
ZN  A1502 (-2.3A)
 0.93A 3aiaA-5ikfA:
undetectable		 3aiaA-5ikfA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ixq RECEPTOR-LIKE
PROTEIN KINASE 5

(Arabidopsis
thaliana) 		PF08263
(LRRNT_2)
PF13855
(LRR_8) 		4 LEU A 170
GLY A 148
LEU A 168
SER A 167
 None
 0.90A 3aiaA-5ixqA:
undetectable		 3aiaA-5ixqA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqs BETA-L-ARABINOBIOSID
ASE

(Bacteroides
thetaiotaomicron) 		PF13088
(BNR_2) 		4 LEU A 349
GLY A  33
LEU A  46
SER A  47
 None
 0.96A 3aiaA-5mqsA:
undetectable		 3aiaA-5mqsA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mz6 SEPARASE

(Caenorhabditis
elegans) 		PF03568
(Peptidase_C50) 		4 MET 1 814
GLY 1 817
LEU 1 812
SER 1 811
 None
 0.94A 3aiaA-5mz61:
undetectable		 3aiaA-5mz61:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t3j INOSITOL
MONOPHOSPHATASE

(Medicago
truncatula) 		PF00459
(Inositol_P) 		4 LEU A 260
GLY A 312
LEU A 210
SER A 211
 None
 0.91A 3aiaA-5t3jA:
undetectable		 3aiaA-5t3jA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5una 7SK SNRNA
METHYLPHOSPHATE
CAPPING ENZYME

(Homo sapiens) 		PF06859
(Bin3)
PF13847
(Methyltransf_31) 		4 LEU A 579
GLY A 472
LEU A 581
SER A 582
 None
None
SAH  A 701 (-4.4A)
SAH  A 701 (-3.6A)
 0.95A 3aiaA-5unaA:
undetectable		 3aiaA-5unaA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5utu ADENOSYLHOMOCYSTEINA
SE

(Cryptosporidium
parvum) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		4 LEU A 254
GLY A 249
LEU A 287
SER A 288
 None
 0.77A 3aiaA-5utuA:
1.4		 3aiaA-5utuA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wls POLLEN RECEPTOR-LIKE
KINASE 3

(Arabidopsis
thaliana) 		no annotation 4 LEU A 194
GLY A 172
LEU A 192
SER A 191
 None
 0.84A 3aiaA-5wlsA:
undetectable		 3aiaA-5wlsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3x BETA-XYLANASE

(Caldicellulosiruptor
owensensis) 		no annotation 4 LEU A 320
GLY A 298
LEU A  12
SER A  11
 None
 0.96A 3aiaA-5y3xA:
undetectable		 3aiaA-5y3xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6baq BPI FOLD-CONTAINING
FAMILY A MEMBER 1

(Mus musculus) 		no annotation 4 LEU A  80
GLY A  82
LEU A 253
SER A 254
 None
 0.90A 3aiaA-6baqA:
undetectable		 3aiaA-6baqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cer PYRUVATE
DEHYDROGENASE E1
COMPONENT SUBUNIT
ALPHA, SOMATIC FORM,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 4 GLY A 122
LEU A 100
SER A 101
CYH A 116
 None
 0.94A 3aiaA-6cerA:
undetectable		 3aiaA-6cerA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g3w PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190

(Arabidopsis
thaliana) 		no annotation 4 LEU B 103
GLY B 105
LEU B 101
SER B 100
 None
 0.96A 3aiaA-6g3wB:
undetectable		 3aiaA-6g3wB:
undetectable