SIMILAR PATTERNS OF AMINO ACIDS FOR 3AI8_B_HNQB255_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1azw PROLINE
IMINOPEPTIDASE


(Xanthomonas
citri)
PF00561
(Abhydrolase_1)
4 GLY A 112
HIS A 294
HIS A 262
CYH A 269
None
1.37A 3ai8B-1azwA:
0.0
3ai8B-1azwA:
21.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1cte CATHEPSIN B

(Rattus
norvegicus)
PF00112
(Peptidase_C1)
5 GLN A  23
GLY A  27
HIS A 110
HIS A 111
TRP A 221
PYS  A 255 (-2.9A)
None
None
None
PYS  A 255 (-4.0A)
0.23A 3ai8B-1cteA:
45.8
3ai8B-1cteA:
82.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fp9 4-ALPHA-GLUCANOTRANS
FERASE


(Thermus
thermophilus)
PF02446
(Glyco_hydro_77)
4 GLN A 256
GLY A 255
HIS A 294
TRP A 258
None
1.41A 3ai8B-1fp9A:
undetectable
3ai8B-1fp9A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ka9 IMIDAZOLE GLYCEROL
PHOSPHATE SYNTHASE


(Thermus
thermophilus)
PF00117
(GATase)
4 GLN H  49
GLY H  13
HIS H 178
CYH H  82
None
1.31A 3ai8B-1ka9H:
undetectable
3ai8B-1ka9H:
22.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qdq CATHEPSIN B

(Bos taurus)
PF00112
(Peptidase_C1)
5 GLN A  23
GLY A  27
HIS A 110
HIS A 111
TRP A 221
074  A 254 ( 3.1A)
074  A 254 ( 3.3A)
074  A 254 ( 3.6A)
074  A 254 ( 3.9A)
074  A 254 (-3.5A)
0.42A 3ai8B-1qdqA:
44.9
3ai8B-1qdqA:
88.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r8w GLYCEROL DEHYDRATASE

(Clostridium
butyricum)
PF01228
(Gly_radical)
PF02901
(PFL-like)
4 GLN A 549
GLY A 638
HIS A 164
CYH A 433
None
1.41A 3ai8B-1r8wA:
0.0
3ai8B-1r8wA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tz7 4-ALPHA-GLUCANOTRANS
FERASE


(Aquifex
aeolicus)
PF02446
(Glyco_hydro_77)
4 GLN A 249
GLY A 248
HIS A 287
TRP A 251
None
1.46A 3ai8B-1tz7A:
undetectable
3ai8B-1tz7A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v0f ENDO-ALPHA-SIALIDASE

(Enterobacteria
phage K1F)
PF12217
(End_beta_propel)
PF12218
(End_N_terminal)
PF12219
(End_tail_spike)
4 GLN A 330
GLY A 705
HIS A 350
TRP A 328
GLN  A 330 ( 0.6A)
GLY  A 705 ( 0.0A)
HIS  A 350 ( 1.0A)
TRP  A 328 ( 0.5A)
1.46A 3ai8B-1v0fA:
undetectable
3ai8B-1v0fA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x2b PROLINE
IMINOPEPTIDASE


(Serratia
marcescens)
PF00561
(Abhydrolase_1)
4 GLY A 115
HIS A 296
HIS A 264
CYH A 271
None
STX  A 401 (-4.5A)
None
STX  A 401 ( 4.9A)
1.43A 3ai8B-1x2bA:
undetectable
3ai8B-1x2bA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z7e PROTEIN ARNA

(Escherichia
coli)
PF00551
(Formyl_trans_N)
PF01370
(Epimerase)
PF02911
(Formyl_trans_C)
4 GLY A  43
HIS A 162
HIS A 163
CYH A 166
None
1.06A 3ai8B-1z7eA:
undetectable
3ai8B-1z7eA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c3d 2-OXOPROPYL-COM
REDUCTASE


(Xanthobacter
autotrophicus)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 GLN A 268
GLY A 269
HIS A 394
CYH A 231
None
1.47A 3ai8B-2c3dA:
undetectable
3ai8B-2c3dA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cfe ALLERGEN

(Malassezia
sympodialis)
PF00160
(Pro_isomerase)
4 GLN A 109
GLY A  73
HIS A  52
HIS A  50
None
1.43A 3ai8B-2cfeA:
undetectable
3ai8B-2cfeA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dzn PROBABLE 26S
PROTEASOME
REGULATORY SUBUNIT
P28


(Saccharomyces
cerevisiae)
PF12796
(Ank_2)
4 GLY A 107
HIS A  77
CYH A 110
TRP A  73
None
1.22A 3ai8B-2dznA:
undetectable
3ai8B-2dznA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2frv PERIPLASMIC
HYDROGENASE


(Desulfovibrio
gigas)
no annotation 4 GLN L 417
GLY L 370
HIS L 108
HIS L 111
None
1.43A 3ai8B-2frvL:
undetectable
3ai8B-2frvL:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hkl L,D-TRANSPEPTIDASE

(Enterococcus
faecium)
PF03734
(YkuD)
PF12229
(PG_binding_4)
4 GLN A 426
GLY A 438
HIS A 421
TRP A 425
None
None
SO4  A   1 (-4.1A)
None
1.48A 3ai8B-2hklA:
undetectable
3ai8B-2hklA:
20.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ipp CATHEPSIN B

(Homo sapiens)
PF00112
(Peptidase_C1)
5 GLN A  23
GLY A  27
HIS B 110
HIS B 111
TRP B 221
PYS  A 255 ( 4.7A)
PYS  A 255 (-3.3A)
None
None
None
0.34A 3ai8B-2ippA:
undetectable
3ai8B-2ippA:
95.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uy1 CLEAVAGE STIMULATION
FACTOR 77


(Encephalitozoon
cuniculi)
PF05843
(Suf)
4 GLN A 228
GLY A 227
HIS A 199
HIS A 202
None
1.33A 3ai8B-2uy1A:
undetectable
3ai8B-2uy1A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vk4 PYRUVATE
DECARBOXYLASE


(Kluyveromyces
lactis)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
4 GLN A 160
GLY A  94
HIS A 225
CYH A 221
None
1.42A 3ai8B-2vk4A:
undetectable
3ai8B-2vk4A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wli POTASSIUM CHANNEL

(Magnetospirillum
magnetotacticum)
PF01007
(IRK)
4 GLN A 295
GLY A 269
HIS A 297
HIS A 298
None
1.11A 3ai8B-2wliA:
undetectable
3ai8B-2wliA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xzo REGULATOR OF
NONSENSE TRANSCRIPTS
1


(Homo sapiens)
PF04851
(ResIII)
PF13086
(AAA_11)
PF13087
(AAA_12)
4 GLN A 491
GLY A 492
HIS A 663
CYH A 664
None
1.49A 3ai8B-2xzoA:
undetectable
3ai8B-2xzoA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9v NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 3


(Thermus
thermophilus)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4)
PF10588
(NADH-G_4Fe-4S_3)
PF13510
(Fer2_4)
4 GLN 3 703
GLY 3 297
HIS 3 702
HIS 3 589
None
1.26A 3ai8B-3i9v3:
undetectable
3ai8B-3i9v3:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jap EIF3C

(Saccharomyces
cerevisiae)
PF00203
(Ribosomal_S19)
4 GLN p 582
GLY p 581
HIS p 611
HIS p 609
None
1.25A 3ai8B-3japp:
undetectable
3ai8B-3japp:
5.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF2


(Schizosaccharomyces
pombe)
PF00076
(RRM_1)
PF16131
(Torus)
4 GLN Y  53
GLY Y 123
HIS Y 135
CYH Y 117
None
None
ZN  Y 501 ( 3.8A)
ZN  Y 501 ( 2.3A)
0.95A 3ai8B-3jb9Y:
undetectable
3ai8B-3jb9Y:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lub PUTATIVE CREATININE
AMIDOHYDROLASE


(Bacteroides
fragilis)
PF02633
(Creatininase)
4 GLY A  28
HIS A  76
HIS A  88
CYH A  86
None
1.36A 3ai8B-3lubA:
undetectable
3ai8B-3lubA:
20.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mor CATHEPSIN B-LIKE
CYSTEINE PROTEASE


(Trypanosoma
brucei)
PF00112
(Peptidase_C1)
4 GLN A 116
GLY A 120
HIS A 194
TRP A 304
None
0.27A 3ai8B-3morA:
37.8
3ai8B-3morA:
39.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3s3r CATHEPSIN B-LIKE
PEPTIDASE (C01
FAMILY)


(Schistosoma
mansoni)
PF00112
(Peptidase_C1)
5 GLN A  94
GLY A  98
HIS A 180
HIS A 181
TRP A 292
0IW  A 324 (-3.0A)
0IW  A 324 (-3.6A)
None
None
0IW  A 324 (-4.5A)
0.37A 3ai8B-3s3rA:
15.7
3ai8B-3s3rA:
57.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1


(Rattus
norvegicus)
no annotation 4 GLN A 160
GLY A 155
HIS A 172
CYH A 150
None
None
ZN  A 228 (-3.3A)
ZN  A 228 (-2.3A)
1.44A 3ai8B-3u9gA:
undetectable
3ai8B-3u9gA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4


(Rattus
norvegicus)
PF00058
(Ldl_recept_b)
PF14670
(FXa_inhibition)
4 GLN C 693
GLY C 423
HIS C 691
HIS C 477
None
1.37A 3ai8B-3v64C:
undetectable
3ai8B-3v64C:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wqy ALANINE--TRNA LIGASE

(Archaeoglobus
fulgidus)
PF01411
(tRNA-synt_2c)
PF02272
(DHHA1)
PF07973
(tRNA_SAD)
4 GLN A 701
GLY A 683
HIS A 604
HIS A 600
None
1.45A 3ai8B-3wqyA:
undetectable
3ai8B-3wqyA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ci7 CELL SURFACE PROTEIN
(PUTATIVE CELL
SURFACE-ASSOCIATED
CYSTEINE PROTEASE)


(Clostridioides
difficile)
PF00112
(Peptidase_C1)
4 GLN A 110
GLY A 111
HIS A 262
HIS A 239
None
1.43A 3ai8B-4ci7A:
19.8
3ai8B-4ci7A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fr2 1,3-PROPANEDIOL
DEHYDROGENASE


(Oenococcus oeni)
PF00465
(Fe-ADH)
4 GLN A 202
GLY A 145
HIS A 267
CYH A 285
NI  A 501 (-2.8A)
None
NI  A 501 (-3.4A)
None
0.96A 3ai8B-4fr2A:
undetectable
3ai8B-4fr2A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fr2 1,3-PROPANEDIOL
DEHYDROGENASE


(Oenococcus oeni)
PF00465
(Fe-ADH)
4 GLN A 202
GLY A 145
HIS A 271
CYH A 285
NI  A 501 (-2.8A)
None
None
None
1.35A 3ai8B-4fr2A:
undetectable
3ai8B-4fr2A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gd3 HYDROGENASE-1 SMALL
CHAIN


(Escherichia
coli)
no annotation 4 GLN S 272
GLY S 274
HIS S 187
CYH S 215
None
None
SF4  S 401 (-3.0A)
SF4  S 401 (-2.1A)
1.22A 3ai8B-4gd3S:
undetectable
3ai8B-4gd3S:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hiz ENDOSIALIDASE

(Enterobacteria
phage phi92)
PF12217
(End_beta_propel)
PF12218
(End_N_terminal)
PF12219
(End_tail_spike)
4 GLN A 160
GLY A 548
HIS A 180
TRP A 158
None
None
CL  A 821 (-4.8A)
EDO  A 810 (-3.5A)
1.48A 3ai8B-4hizA:
undetectable
3ai8B-4hizA:
17.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4i05 CATHEPSIN B-LIKE
PEPTIDASE (C01
FAMILY)


(Schistosoma
mansoni)
PF00112
(Peptidase_C1)
5 GLN A  94
GLY A  98
HIS A 180
HIS A 181
TRP A 292
CSO  A 100 ( 3.5A)
CSO  A 100 ( 3.9A)
None
None
None
0.24A 3ai8B-4i05A:
42.3
3ai8B-4i05A:
52.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kq7 HYPOTHETICAL PROTEIN

(Bacteroides
uniformis)
PF11175
(DUF2961)
4 GLN A 370
GLY A 254
HIS A 213
TRP A 368
None
1.24A 3ai8B-4kq7A:
undetectable
3ai8B-4kq7A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lmh EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT OMCA


(Shewanella
oneidensis)
no annotation 4 GLN A 142
GLY A 259
HIS A 240
CYH A 253
HEC  A 802 (-3.4A)
None
HEC  A 802 (-3.2A)
HEC  A 802 (-2.0A)
0.77A 3ai8B-4lmhA:
undetectable
3ai8B-4lmhA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o2w E3 UBIQUITIN-PROTEIN
LIGASE HERC1


(Homo sapiens)
PF00415
(RCC1)
4 GLN A4009
GLY A4052
HIS A4354
CYH A4034
None
1.21A 3ai8B-4o2wA:
undetectable
3ai8B-4o2wA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4okd ISOAMYLASE

(Chlamydomonas
reinhardtii)
PF00128
(Alpha-amylase)
PF02922
(CBM_48)
4 GLN A 177
GLY A 410
HIS A 176
HIS A 188
None
1.13A 3ai8B-4okdA:
undetectable
3ai8B-4okdA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q1v PUTATIVE DIPEPTIDYL
AMINOPEPTIDASE IV


(Bacteroides
ovatus)
PF00326
(Peptidase_S9)
PF00930
(DPPIV_N)
4 GLY A 605
HIS A 710
CYH A 681
TRP A 602
None
1.20A 3ai8B-4q1vA:
undetectable
3ai8B-4q1vA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3p 4-ALPHA-GLUCANOTRANS
FERASE


(Escherichia
coli)
PF02446
(Glyco_hydro_77)
4 GLN A 411
GLY A 410
HIS A 449
TRP A 413
None
1.46A 3ai8B-4s3pA:
undetectable
3ai8B-4s3pA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ycz FUSION PROTEIN OF
SEC13 AND NUP145C


(Thermothelomyces
thermophila)
PF00400
(WD40)
PF12110
(Nup96)
4 GLY A  63
HIS A  22
CYH A  36
TRP A  66
None
1.46A 3ai8B-4yczA:
undetectable
3ai8B-4yczA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yzz TRAP TRANSPORTER
SOLUTE BINDING
PROTEIN


(Bordetella
bronchiseptica)
PF03480
(DctP)
4 GLY A  51
HIS A  97
CYH A 152
TRP A  42
None
1.29A 3ai8B-4yzzA:
undetectable
3ai8B-4yzzA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i2g DIOL DEHYDRATASE

(Roseburia
inulinivorans)
PF01228
(Gly_radical)
PF02901
(PFL-like)
4 GLN A 554
GLY A 692
HIS A 166
CYH A 438
None
None
PGO  A 901 (-4.0A)
PGO  A 901 (-3.6A)
1.40A 3ai8B-5i2gA:
undetectable
3ai8B-5i2gA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjh 4-ALPHA-GLUCANOTRANS
FERASE


(Corynebacterium
glutamicum)
PF02446
(Glyco_hydro_77)
4 GLN A 423
GLY A 422
HIS A 461
TRP A 425
None
1.49A 3ai8B-5jjhA:
undetectable
3ai8B-5jjhA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k5l TRANSCRIPTIONAL
REPRESSOR CTCF


(Homo sapiens)
PF00096
(zf-C2H2)
PF13894
(zf-C2H2_4)
4 GLY E 453
HIS E 460
HIS E 441
CYH E 439
None
ZN  E 501 (-3.1A)
None
ZN  E 501 (-2.3A)
1.48A 3ai8B-5k5lE:
undetectable
3ai8B-5k5lE:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kdm MAJOR TEGUMENT
PROTEIN


(Human
gammaherpesvirus
4)
PF12818
(Tegument_dsDNA)
4 GLN D 514
GLY D 516
HIS D 392
CYH D 438
None
1.22A 3ai8B-5kdmD:
undetectable
3ai8B-5kdmD:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n28 METHYL-COENZYME M
REDUCTASE SUBUNIT
ALPHA


(Methanotorris
formicicus)
PF02249
(MCR_alpha)
PF02745
(MCR_alpha_N)
4 GLN A 233
GLY A 146
CYH A 164
TRP A 229
F43  A 604 (-4.0A)
None
None
None
1.25A 3ai8B-5n28A:
undetectable
3ai8B-5n28A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gdt -

(-)
no annotation 4 GLN A  61
GLY A  60
HIS A  63
HIS A  51
None
1.50A 3ai8B-6gdtA:
undetectable
3ai8B-6gdtA:
undetectable