SIMILAR PATTERNS OF AMINO ACIDS FOR 3AI8_B_HNQB255_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1azw | PROLINEIMINOPEPTIDASE (Xanthomonascitri) |
PF00561(Abhydrolase_1) | 4 | GLY A 112HIS A 294HIS A 262CYH A 269 | None | 1.37A | 3ai8B-1azwA:0.0 | 3ai8B-1azwA:21.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1cte | CATHEPSIN B (Rattusnorvegicus) |
PF00112(Peptidase_C1) | 5 | GLN A 23GLY A 27HIS A 110HIS A 111TRP A 221 | PYS A 255 (-2.9A)NoneNoneNonePYS A 255 (-4.0A) | 0.23A | 3ai8B-1cteA:45.8 | 3ai8B-1cteA:82.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fp9 | 4-ALPHA-GLUCANOTRANSFERASE (Thermusthermophilus) |
PF02446(Glyco_hydro_77) | 4 | GLN A 256GLY A 255HIS A 294TRP A 258 | None | 1.41A | 3ai8B-1fp9A:undetectable | 3ai8B-1fp9A:17.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ka9 | IMIDAZOLE GLYCEROLPHOSPHATE SYNTHASE (Thermusthermophilus) |
PF00117(GATase) | 4 | GLN H 49GLY H 13HIS H 178CYH H 82 | None | 1.31A | 3ai8B-1ka9H:undetectable | 3ai8B-1ka9H:22.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1qdq | CATHEPSIN B (Bos taurus) |
PF00112(Peptidase_C1) | 5 | GLN A 23GLY A 27HIS A 110HIS A 111TRP A 221 | 074 A 254 ( 3.1A)074 A 254 ( 3.3A)074 A 254 ( 3.6A)074 A 254 ( 3.9A)074 A 254 (-3.5A) | 0.42A | 3ai8B-1qdqA:44.9 | 3ai8B-1qdqA:88.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r8w | GLYCEROL DEHYDRATASE (Clostridiumbutyricum) |
PF01228(Gly_radical)PF02901(PFL-like) | 4 | GLN A 549GLY A 638HIS A 164CYH A 433 | None | 1.41A | 3ai8B-1r8wA:0.0 | 3ai8B-1r8wA:16.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tz7 | 4-ALPHA-GLUCANOTRANSFERASE (Aquifexaeolicus) |
PF02446(Glyco_hydro_77) | 4 | GLN A 249GLY A 248HIS A 287TRP A 251 | None | 1.46A | 3ai8B-1tz7A:undetectable | 3ai8B-1tz7A:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v0f | ENDO-ALPHA-SIALIDASE (Enterobacteriaphage K1F) |
PF12217(End_beta_propel)PF12218(End_N_terminal)PF12219(End_tail_spike) | 4 | GLN A 330GLY A 705HIS A 350TRP A 328 | GLN A 330 ( 0.6A)GLY A 705 ( 0.0A)HIS A 350 ( 1.0A)TRP A 328 ( 0.5A) | 1.46A | 3ai8B-1v0fA:undetectable | 3ai8B-1v0fA:17.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x2b | PROLINEIMINOPEPTIDASE (Serratiamarcescens) |
PF00561(Abhydrolase_1) | 4 | GLY A 115HIS A 296HIS A 264CYH A 271 | NoneSTX A 401 (-4.5A)NoneSTX A 401 ( 4.9A) | 1.43A | 3ai8B-1x2bA:undetectable | 3ai8B-1x2bA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z7e | PROTEIN ARNA (Escherichiacoli) |
PF00551(Formyl_trans_N)PF01370(Epimerase)PF02911(Formyl_trans_C) | 4 | GLY A 43HIS A 162HIS A 163CYH A 166 | None | 1.06A | 3ai8B-1z7eA:undetectable | 3ai8B-1z7eA:16.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c3d | 2-OXOPROPYL-COMREDUCTASE (Xanthobacterautotrophicus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | GLN A 268GLY A 269HIS A 394CYH A 231 | None | 1.47A | 3ai8B-2c3dA:undetectable | 3ai8B-2c3dA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cfe | ALLERGEN (Malasseziasympodialis) |
PF00160(Pro_isomerase) | 4 | GLN A 109GLY A 73HIS A 52HIS A 50 | None | 1.43A | 3ai8B-2cfeA:undetectable | 3ai8B-2cfeA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dzn | PROBABLE 26SPROTEASOMEREGULATORY SUBUNITP28 (Saccharomycescerevisiae) |
PF12796(Ank_2) | 4 | GLY A 107HIS A 77CYH A 110TRP A 73 | None | 1.22A | 3ai8B-2dznA:undetectable | 3ai8B-2dznA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2frv | PERIPLASMICHYDROGENASE (Desulfovibriogigas) |
no annotation | 4 | GLN L 417GLY L 370HIS L 108HIS L 111 | None | 1.43A | 3ai8B-2frvL:undetectable | 3ai8B-2frvL:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hkl | L,D-TRANSPEPTIDASE (Enterococcusfaecium) |
PF03734(YkuD)PF12229(PG_binding_4) | 4 | GLN A 426GLY A 438HIS A 421TRP A 425 | NoneNoneSO4 A 1 (-4.1A)None | 1.48A | 3ai8B-2hklA:undetectable | 3ai8B-2hklA:20.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ipp | CATHEPSIN B (Homo sapiens) |
PF00112(Peptidase_C1) | 5 | GLN A 23GLY A 27HIS B 110HIS B 111TRP B 221 | PYS A 255 ( 4.7A)PYS A 255 (-3.3A)NoneNoneNone | 0.34A | 3ai8B-2ippA:undetectable | 3ai8B-2ippA:95.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uy1 | CLEAVAGE STIMULATIONFACTOR 77 (Encephalitozooncuniculi) |
PF05843(Suf) | 4 | GLN A 228GLY A 227HIS A 199HIS A 202 | None | 1.33A | 3ai8B-2uy1A:undetectable | 3ai8B-2uy1A:16.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vk4 | PYRUVATEDECARBOXYLASE (Kluyveromyceslactis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | GLN A 160GLY A 94HIS A 225CYH A 221 | None | 1.42A | 3ai8B-2vk4A:undetectable | 3ai8B-2vk4A:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wli | POTASSIUM CHANNEL (Magnetospirillummagnetotacticum) |
PF01007(IRK) | 4 | GLN A 295GLY A 269HIS A 297HIS A 298 | None | 1.11A | 3ai8B-2wliA:undetectable | 3ai8B-2wliA:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xzo | REGULATOR OFNONSENSE TRANSCRIPTS1 (Homo sapiens) |
PF04851(ResIII)PF13086(AAA_11)PF13087(AAA_12) | 4 | GLN A 491GLY A 492HIS A 663CYH A 664 | None | 1.49A | 3ai8B-2xzoA:undetectable | 3ai8B-2xzoA:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i9v | NADH-QUINONEOXIDOREDUCTASESUBUNIT 3 (Thermusthermophilus) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4)PF10588(NADH-G_4Fe-4S_3)PF13510(Fer2_4) | 4 | GLN 3 703GLY 3 297HIS 3 702HIS 3 589 | None | 1.26A | 3ai8B-3i9v3:undetectable | 3ai8B-3i9v3:14.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jap | EIF3C (Saccharomycescerevisiae) |
PF00203(Ribosomal_S19) | 4 | GLN p 582GLY p 581HIS p 611HIS p 609 | None | 1.25A | 3ai8B-3japp:undetectable | 3ai8B-3japp:5.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb9 | PRE-MRNA-SPLICINGFACTOR CWF2 (Schizosaccharomycespombe) |
PF00076(RRM_1)PF16131(Torus) | 4 | GLN Y 53GLY Y 123HIS Y 135CYH Y 117 | NoneNone ZN Y 501 ( 3.8A) ZN Y 501 ( 2.3A) | 0.95A | 3ai8B-3jb9Y:undetectable | 3ai8B-3jb9Y:14.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lub | PUTATIVE CREATININEAMIDOHYDROLASE (Bacteroidesfragilis) |
PF02633(Creatininase) | 4 | GLY A 28HIS A 76HIS A 88CYH A 86 | None | 1.36A | 3ai8B-3lubA:undetectable | 3ai8B-3lubA:20.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3mor | CATHEPSIN B-LIKECYSTEINE PROTEASE (Trypanosomabrucei) |
PF00112(Peptidase_C1) | 4 | GLN A 116GLY A 120HIS A 194TRP A 304 | None | 0.27A | 3ai8B-3morA:37.8 | 3ai8B-3morA:39.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3s3r | CATHEPSIN B-LIKEPEPTIDASE (C01FAMILY) (Schistosomamansoni) |
PF00112(Peptidase_C1) | 5 | GLN A 94GLY A 98HIS A 180HIS A 181TRP A 292 | 0IW A 324 (-3.0A)0IW A 324 (-3.6A)NoneNone0IW A 324 (-4.5A) | 0.37A | 3ai8B-3s3rA:15.7 | 3ai8B-3s3rA:57.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u9g | ZINC FINGERCCCH-TYPE ANTIVIRALPROTEIN 1 (Rattusnorvegicus) |
no annotation | 4 | GLN A 160GLY A 155HIS A 172CYH A 150 | NoneNone ZN A 228 (-3.3A) ZN A 228 (-2.3A) | 1.44A | 3ai8B-3u9gA:undetectable | 3ai8B-3u9gA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v64 | LOW-DENSITYLIPOPROTEINRECEPTOR-RELATEDPROTEIN 4 (Rattusnorvegicus) |
PF00058(Ldl_recept_b)PF14670(FXa_inhibition) | 4 | GLN C 693GLY C 423HIS C 691HIS C 477 | None | 1.37A | 3ai8B-3v64C:undetectable | 3ai8B-3v64C:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wqy | ALANINE--TRNA LIGASE (Archaeoglobusfulgidus) |
PF01411(tRNA-synt_2c)PF02272(DHHA1)PF07973(tRNA_SAD) | 4 | GLN A 701GLY A 683HIS A 604HIS A 600 | None | 1.45A | 3ai8B-3wqyA:undetectable | 3ai8B-3wqyA:14.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ci7 | CELL SURFACE PROTEIN(PUTATIVE CELLSURFACE-ASSOCIATEDCYSTEINE PROTEASE) (Clostridioidesdifficile) |
PF00112(Peptidase_C1) | 4 | GLN A 110GLY A 111HIS A 262HIS A 239 | None | 1.43A | 3ai8B-4ci7A:19.8 | 3ai8B-4ci7A:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fr2 | 1,3-PROPANEDIOLDEHYDROGENASE (Oenococcus oeni) |
PF00465(Fe-ADH) | 4 | GLN A 202GLY A 145HIS A 267CYH A 285 | NI A 501 (-2.8A)None NI A 501 (-3.4A)None | 0.96A | 3ai8B-4fr2A:undetectable | 3ai8B-4fr2A:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fr2 | 1,3-PROPANEDIOLDEHYDROGENASE (Oenococcus oeni) |
PF00465(Fe-ADH) | 4 | GLN A 202GLY A 145HIS A 271CYH A 285 | NI A 501 (-2.8A)NoneNoneNone | 1.35A | 3ai8B-4fr2A:undetectable | 3ai8B-4fr2A:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gd3 | HYDROGENASE-1 SMALLCHAIN (Escherichiacoli) |
no annotation | 4 | GLN S 272GLY S 274HIS S 187CYH S 215 | NoneNoneSF4 S 401 (-3.0A)SF4 S 401 (-2.1A) | 1.22A | 3ai8B-4gd3S:undetectable | 3ai8B-4gd3S:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hiz | ENDOSIALIDASE (Enterobacteriaphage phi92) |
PF12217(End_beta_propel)PF12218(End_N_terminal)PF12219(End_tail_spike) | 4 | GLN A 160GLY A 548HIS A 180TRP A 158 | NoneNone CL A 821 (-4.8A)EDO A 810 (-3.5A) | 1.48A | 3ai8B-4hizA:undetectable | 3ai8B-4hizA:17.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4i05 | CATHEPSIN B-LIKEPEPTIDASE (C01FAMILY) (Schistosomamansoni) |
PF00112(Peptidase_C1) | 5 | GLN A 94GLY A 98HIS A 180HIS A 181TRP A 292 | CSO A 100 ( 3.5A)CSO A 100 ( 3.9A)NoneNoneNone | 0.24A | 3ai8B-4i05A:42.3 | 3ai8B-4i05A:52.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kq7 | HYPOTHETICAL PROTEIN (Bacteroidesuniformis) |
PF11175(DUF2961) | 4 | GLN A 370GLY A 254HIS A 213TRP A 368 | None | 1.24A | 3ai8B-4kq7A:undetectable | 3ai8B-4kq7A:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lmh | EXTRACELLULAR IRONOXIDE RESPIRATORYSYSTEM SURFACEDECAHEME CYTOCHROMEC COMPONENT OMCA (Shewanellaoneidensis) |
no annotation | 4 | GLN A 142GLY A 259HIS A 240CYH A 253 | HEC A 802 (-3.4A)NoneHEC A 802 (-3.2A)HEC A 802 (-2.0A) | 0.77A | 3ai8B-4lmhA:undetectable | 3ai8B-4lmhA:16.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o2w | E3 UBIQUITIN-PROTEINLIGASE HERC1 (Homo sapiens) |
PF00415(RCC1) | 4 | GLN A4009GLY A4052HIS A4354CYH A4034 | None | 1.21A | 3ai8B-4o2wA:undetectable | 3ai8B-4o2wA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4okd | ISOAMYLASE (Chlamydomonasreinhardtii) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 4 | GLN A 177GLY A 410HIS A 176HIS A 188 | None | 1.13A | 3ai8B-4okdA:undetectable | 3ai8B-4okdA:13.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q1v | PUTATIVE DIPEPTIDYLAMINOPEPTIDASE IV (Bacteroidesovatus) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 4 | GLY A 605HIS A 710CYH A 681TRP A 602 | None | 1.20A | 3ai8B-4q1vA:undetectable | 3ai8B-4q1vA:17.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3p | 4-ALPHA-GLUCANOTRANSFERASE (Escherichiacoli) |
PF02446(Glyco_hydro_77) | 4 | GLN A 411GLY A 410HIS A 449TRP A 413 | None | 1.46A | 3ai8B-4s3pA:undetectable | 3ai8B-4s3pA:15.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ycz | FUSION PROTEIN OFSEC13 AND NUP145C (Thermothelomycesthermophila) |
PF00400(WD40)PF12110(Nup96) | 4 | GLY A 63HIS A 22CYH A 36TRP A 66 | None | 1.46A | 3ai8B-4yczA:undetectable | 3ai8B-4yczA:15.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzz | TRAP TRANSPORTERSOLUTE BINDINGPROTEIN (Bordetellabronchiseptica) |
PF03480(DctP) | 4 | GLY A 51HIS A 97CYH A 152TRP A 42 | None | 1.29A | 3ai8B-4yzzA:undetectable | 3ai8B-4yzzA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i2g | DIOL DEHYDRATASE (Roseburiainulinivorans) |
PF01228(Gly_radical)PF02901(PFL-like) | 4 | GLN A 554GLY A 692HIS A 166CYH A 438 | NoneNonePGO A 901 (-4.0A)PGO A 901 (-3.6A) | 1.40A | 3ai8B-5i2gA:undetectable | 3ai8B-5i2gA:15.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jjh | 4-ALPHA-GLUCANOTRANSFERASE (Corynebacteriumglutamicum) |
PF02446(Glyco_hydro_77) | 4 | GLN A 423GLY A 422HIS A 461TRP A 425 | None | 1.49A | 3ai8B-5jjhA:undetectable | 3ai8B-5jjhA:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k5l | TRANSCRIPTIONALREPRESSOR CTCF (Homo sapiens) |
PF00096(zf-C2H2)PF13894(zf-C2H2_4) | 4 | GLY E 453HIS E 460HIS E 441CYH E 439 | None ZN E 501 (-3.1A)None ZN E 501 (-2.3A) | 1.48A | 3ai8B-5k5lE:undetectable | 3ai8B-5k5lE:13.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kdm | MAJOR TEGUMENTPROTEIN (Humangammaherpesvirus4) |
PF12818(Tegument_dsDNA) | 4 | GLN D 514GLY D 516HIS D 392CYH D 438 | None | 1.22A | 3ai8B-5kdmD:undetectable | 3ai8B-5kdmD:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n28 | METHYL-COENZYME MREDUCTASE SUBUNITALPHA (Methanotorrisformicicus) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 4 | GLN A 233GLY A 146CYH A 164TRP A 229 | F43 A 604 (-4.0A)NoneNoneNone | 1.25A | 3ai8B-5n28A:undetectable | 3ai8B-5n28A:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gdt | - (-) |
no annotation | 4 | GLN A 61GLY A 60HIS A 63HIS A 51 | None | 1.50A | 3ai8B-6gdtA:undetectable | 3ai8B-6gdtA:undetectable |