SIMILAR PATTERNS OF AMINO ACIDS FOR 3AG4_B_CHDB1085

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhy P64K

(Neisseria
meningitidis) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 MET A 548
GLY A 546
GLU A 483
THR A 480
GLY A 539
 None
 1.47A 3ag4A-1bhyA:
0.0
3ag4B-1bhyA:
0.0
3ag4T-1bhyA:
0.0		 3ag4A-1bhyA:
20.07
3ag4B-1bhyA:
18.46
3ag4T-1bhyA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eg7 FORMYLTETRAHYDROFOLA
TE SYNTHETASE

(Moorella
thermoacetica) 		PF01268
(FTHFS) 		5 GLY A1415
GLU A1264
THR A1266
THR A1082
GLY A1113
 None
 1.48A 3ag4A-1eg7A:
0.0
3ag4B-1eg7A:
0.0
3ag4T-1eg7A:
0.0		 3ag4A-1eg7A:
23.31
3ag4B-1eg7A:
17.74
3ag4T-1eg7A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hcy ARTHROPODAN
HEMOCYANIN

(Panulirus
interruptus) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		5 GLY A 185
GLN A 179
GLU A 186
ARG A 382
PHE A 381
 None
 1.39A 3ag4A-1hcyA:
0.0
3ag4B-1hcyA:
0.0
3ag4T-1hcyA:
0.0		 3ag4A-1hcyA:
21.45
3ag4B-1hcyA:
16.06
3ag4T-1hcyA:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k5s PENICILLIN G ACYLASE
BETA SUBUNIT

(Escherichia
coli) 		PF01804
(Penicil_amidase) 		5 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.22A 3ag4A-1k5sB:
0.0
3ag4B-1k5sB:
0.0
3ag4T-1k5sB:
0.0		 3ag4A-1k5sB:
20.53
3ag4B-1k5sB:
17.45
3ag4T-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wk4 TTK003001606

(Thermus
thermophilus) 		PF00583
(Acetyltransf_1) 		5 GLN A 101
THR A  21
THR A  25
PHE A 139
GLY A 136
 None
None
None
MES  A 201 ( 4.3A)
MES  A 201 (-3.3A)
 1.23A 3ag4A-1wk4A:
undetectable
3ag4B-1wk4A:
0.0
3ag4T-1wk4A:
undetectable		 3ag4A-1wk4A:
14.65
3ag4B-1wk4A:
21.15
3ag4T-1wk4A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gsk VITAMIN B12
TRANSPORTER BTUB

(Escherichia
coli) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		5 GLY A 119
GLN A 372
THR A 391
ARG A  19
GLY A 125
 None
 1.36A 3ag4A-2gskA:
undetectable
3ag4B-2gskA:
0.0
3ag4T-2gskA:
0.0		 3ag4A-2gskA:
21.56
3ag4B-2gskA:
14.48
3ag4T-2gskA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jjq UNCHARACTERIZED RNA
METHYLTRANSFERASE
PYRAB10780

(Pyrococcus
abyssi) 		PF05958
(tRNA_U5-meth_tr) 		5 GLY A 180
GLU A 236
ARG A 108
PHE A 140
GLY A 106
 None
 0.98A 3ag4A-2jjqA:
0.0
3ag4B-2jjqA:
0.0
3ag4T-2jjqA:
0.0		 3ag4A-2jjqA:
19.55
3ag4B-2jjqA:
16.82
3ag4T-2jjqA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o5h HYPOTHETICAL PROTEIN

(Neisseria
meningitidis) 		PF04591
(DUF596) 		5 MET A 109
GLY A 108
TRP A 110
THR A  49
PHE A 105
 None
 1.29A 3ag4A-2o5hA:
1.1
3ag4B-2o5hA:
0.0
3ag4T-2o5hA:
0.0		 3ag4A-2o5hA:
13.45
3ag4B-2o5hA:
20.83
3ag4T-2o5hA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wnb -

(Sus scrofa) 		PF00777
(Glyco_transf_29) 		5 GLY A 291
THR A 328
ARG A 171
PHE A 192
GLY A 273
 None
None
None
None
C5P  A1344 (-3.2A)
 1.49A 3ag4A-2wnbA:
0.0
3ag4B-2wnbA:
0.0
3ag4T-2wnbA:
0.0		 3ag4A-2wnbA:
17.88
3ag4B-2wnbA:
18.98
3ag4T-2wnbA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA

(Escherichia
coli) 		PF00232
(Glyco_hydro_1) 		5 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.40A 3ag4A-2xhyA:
0.0
3ag4B-2xhyA:
undetectable
3ag4T-2xhyA:
undetectable		 3ag4A-2xhyA:
20.62
3ag4B-2xhyA:
18.60
3ag4T-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2

(Bos taurus) 		PF02046
(COX6A) 		5 ARG G  14
ARG G  17
PHE G  18
PHE G  21
GLY G  22
 CHD  G1085 (-3.9A)
CHD  G1085 (-4.4A)
CHD  G1085 ( 4.3A)
None
CHD  G1085 (-3.5A)
 0.00A 3ag4A-2y69G:
undetectable
3ag4B-2y69G:
undetectable
3ag4T-2y69G:
9.8		 3ag4A-2y69G:
11.22
3ag4B-2y69G:
20.35
3ag4T-2y69G:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bt7 TRNA
(URACIL-5-)-METHYLTR
ANSFERASE

(Escherichia
coli) 		PF05958
(tRNA_U5-meth_tr) 		5 MET A 179
GLU A 170
ARG A 230
PHE A 224
GLY A 222
 None
 1.44A 3ag4A-3bt7A:
0.0
3ag4B-3bt7A:
undetectable
3ag4T-3bt7A:
undetectable		 3ag4A-3bt7A:
20.94
3ag4B-3bt7A:
20.40
3ag4T-3bt7A:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ce6 ADENOSYLHOMOCYSTEINA
SE

(Mycobacterium
tuberculosis) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		5 GLY A 359
THR A 269
ARG A 406
PHE A  96
GLY A 411
 None
 1.24A 3ag4A-3ce6A:
undetectable
3ag4B-3ce6A:
undetectable
3ag4T-3ce6A:
undetectable		 3ag4A-3ce6A:
22.59
3ag4B-3ce6A:
18.09
3ag4T-3ce6A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cvr INVASION PLASMID
ANTIGEN

(Shigella
flexneri) 		PF12468
(TTSSLRR)
PF14496
(NEL) 		5 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.41A 3ag4A-3cvrA:
undetectable
3ag4B-3cvrA:
undetectable
3ag4T-3cvrA:
undetectable		 3ag4A-3cvrA:
22.78
3ag4B-3cvrA:
18.50
3ag4T-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fgb UNCHARACTERIZED
PROTEIN Q89ZH8_BACTN

(Bacteroides
thetaiotaomicron) 		PF10282
(Lactonase) 		5 GLY A 153
THR A 129
ARG A 112
PHE A 104
GLY A  83
 None
 1.30A 3ag4A-3fgbA:
undetectable
3ag4B-3fgbA:
undetectable
3ag4T-3fgbA:
undetectable		 3ag4A-3fgbA:
20.44
3ag4B-3fgbA:
21.47
3ag4T-3fgbA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hn0 NITRATE TRANSPORT
PROTEIN

(Parabacteroides
distasonis) 		no annotation 5 GLY A 199
GLN A 202
THR A 203
ARG A 137
GLY A 275
 None
 1.47A 3ag4A-3hn0A:
undetectable
3ag4B-3hn0A:
undetectable
3ag4T-3hn0A:
undetectable		 3ag4A-3hn0A:
19.48
3ag4B-3hn0A:
21.92
3ag4T-3hn0A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j4u MAJOR CAPSID PROTEIN

(Bordetella
virus BPP1) 		no annotation 5 MET A  87
GLY A  88
GLN A 126
THR A 125
GLY A 144
 None
 1.46A 3ag4A-3j4uA:
undetectable
3ag4B-3j4uA:
undetectable
3ag4T-3j4uA:
undetectable		 3ag4A-3j4uA:
21.07
3ag4B-3j4uA:
21.30
3ag4T-3j4uA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s9b VIPERA RUSSELLI
PROTEINASE RVV-V
GAMMA

(Daboia
siamensis) 		PF00089
(Trypsin) 		5 GLY A  18
ARG A 137
ARG A 135
PHE A 161
GLY A 184
 None
 1.12A 3ag4A-3s9bA:
undetectable
3ag4B-3s9bA:
undetectable
3ag4T-3s9bA:
undetectable		 3ag4A-3s9bA:
19.00
3ag4B-3s9bA:
21.01
3ag4T-3s9bA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3urh DIHYDROLIPOYL
DEHYDROGENASE

(Sinorhizobium
meliloti) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 GLN A 356
GLU A 358
THR A 355
PHE A 383
GLY A 397
 None
 1.36A 3ag4A-3urhA:
0.6
3ag4B-3urhA:
undetectable
3ag4T-3urhA:
undetectable		 3ag4A-3urhA:
21.90
3ag4B-3urhA:
16.27
3ag4T-3urhA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wy7 8-AMINO-7-OXONONANOA
TE SYNTHASE

(Mycolicibacterium
smegmatis) 		PF00155
(Aminotran_1_2) 		5 GLY A 214
GLU A 201
THR A 230
THR A 231
GLY A  94
 None
 1.34A 3ag4A-3wy7A:
undetectable
3ag4B-3wy7A:
undetectable
3ag4T-3wy7A:
undetectable		 3ag4A-3wy7A:
21.19
3ag4B-3wy7A:
19.49
3ag4T-3wy7A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cgy DNA TOPOISOMERASE
3-ALPHA

(Homo sapiens) 		PF01131
(Topoisom_bac)
PF01751
(Toprim) 		5 MET A 566
GLY A 565
THR A 544
PHE A 559
GLY A 552
 None
 1.49A 3ag4A-4cgyA:
1.6
3ag4B-4cgyA:
undetectable
3ag4T-4cgyA:
undetectable		 3ag4A-4cgyA:
20.21
3ag4B-4cgyA:
12.96
3ag4T-4cgyA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cu8 GLYCOSIDE HYDROLASE
2

(Streptococcus
pneumoniae) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF16355
(DUF4982) 		6 GLY A 597
GLN A 503
GLU A 505
THR A 482
PHE A 444
GLY A 643
 None
 1.40A 3ag4A-4cu8A:
undetectable
3ag4B-4cu8A:
undetectable
3ag4T-4cu8A:
undetectable		 3ag4A-4cu8A:
20.58
3ag4B-4cu8A:
14.29
3ag4T-4cu8A:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cu8 GLYCOSIDE HYDROLASE
2

(Streptococcus
pneumoniae) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF16355
(DUF4982) 		5 GLY A 597
THR A 482
THR A 483
PHE A 444
GLY A 643
 None
 1.44A 3ag4A-4cu8A:
undetectable
3ag4B-4cu8A:
undetectable
3ag4T-4cu8A:
undetectable		 3ag4A-4cu8A:
20.58
3ag4B-4cu8A:
14.29
3ag4T-4cu8A:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j05 PHOSPHATE
TRANSPORTER

(Serendipita
indica) 		PF00083
(Sugar_tr) 		5 GLY A 315
THR A 433
THR A 434
PHE A 493
GLY A 492
 None
 1.14A 3ag4A-4j05A:
0.7
3ag4B-4j05A:
undetectable
3ag4T-4j05A:
undetectable		 3ag4A-4j05A:
23.83
3ag4B-4j05A:
17.55
3ag4T-4j05A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lls GERANYLTRANSTRANSFER
ASE

(Roseobacter
denitrificans) 		PF00348
(polyprenyl_synt) 		5 MET A 149
GLY A 177
GLN A 175
ARG A  44
GLY A 184
 GST  A 302 ( 4.1A)
None
None
IPE  A 301 (-3.1A)
None
 1.41A 3ag4A-4llsA:
1.3
3ag4B-4llsA:
undetectable
3ag4T-4llsA:
undetectable		 3ag4A-4llsA:
20.31
3ag4B-4llsA:
22.93
3ag4T-4llsA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qdg PUTATIVE ADHESIN

(Bacteroides
thetaiotaomicron) 		PF08842
(Mfa2) 		5 MET A 175
THR A  67
ARG A 253
PHE A 119
GLY A 153
 None
 1.31A 3ag4A-4qdgA:
undetectable
3ag4B-4qdgA:
undetectable
3ag4T-4qdgA:
undetectable		 3ag4A-4qdgA:
20.49
3ag4B-4qdgA:
23.20
3ag4T-4qdgA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ri2 PHOTOSYSTEM II 22
KDA PROTEIN,
CHLOROPLASTIC

(Spinacia
oleracea) 		PF00504
(Chloroa_b-bind) 		5 GLN A 169
GLU A 159
THR A 162
PHE A 152
PHE A 154
 None
 1.25A 3ag4A-4ri2A:
1.4
3ag4B-4ri2A:
undetectable
3ag4T-4ri2A:
undetectable		 3ag4A-4ri2A:
18.06
3ag4B-4ri2A:
21.95
3ag4T-4ri2A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v1u LYND

(Lyngbya
aestuarii) 		PF02624
(YcaO) 		5 GLN A 643
GLU A 640
THR A 639
ARG A 384
GLY A 420
 None
CA  A1777 (-2.7A)
None
None
None
 1.43A 3ag4A-4v1uA:
undetectable
3ag4B-4v1uA:
undetectable
3ag4T-4v1uA:
undetectable		 3ag4A-4v1uA:
22.14
3ag4B-4v1uA:
14.64
3ag4T-4v1uA:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c59 MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB

(Escherichia
coli) 		PF12704
(MacB_PCD) 		5 GLY A  75
THR A  53
THR A 177
PHE A  94
GLY A  78
 None
 1.49A 3ag4A-5c59A:
undetectable
3ag4B-5c59A:
undetectable
3ag4T-5c59A:
undetectable		 3ag4A-5c59A:
17.69
3ag4B-5c59A:
22.93
3ag4T-5c59A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e26 PANTOTHENATE KINASE
2, MITOCHONDRIAL

(Homo sapiens) 		PF03630
(Fumble) 		5 MET A 298
GLY A 299
THR A 327
PHE A 295
PHE A 321
 None
 1.21A 3ag4A-5e26A:
undetectable
3ag4B-5e26A:
undetectable
3ag4T-5e26A:
undetectable		 3ag4A-5e26A:
20.53
3ag4B-5e26A:
19.84
3ag4T-5e26A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gq0 EPITHIOSPECIFIER
PROTEIN

(Arabidopsis
thaliana) 		no annotation 5 GLY B  39
THR B  73
ARG B  94
PHE B 100
GLY B  92
 None
 1.21A 3ag4A-5gq0B:
undetectable
3ag4B-5gq0B:
undetectable
3ag4T-5gq0B:
undetectable		 3ag4A-5gq0B:
20.15
3ag4B-5gq0B:
18.62
3ag4T-5gq0B:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u25 DIHYDROLIPOAMIDE
DEHYDROGENASE (E3
COMPONENT OF
PYRUVATE AND
2-OXOGLUTARATE
DEHYDROGENASE
COMPLEXES)

(Neisseria
gonorrhoeae) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 MET A 543
GLY A 541
GLU A 478
THR A 475
GLY A 534
 None
 1.46A 3ag4A-5u25A:
2.1
3ag4B-5u25A:
undetectable
3ag4T-5u25A:
undetectable		 3ag4A-5u25A:
20.66
3ag4B-5u25A:
15.97
3ag4T-5u25A:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ww1 PULULLANASE

(Paenibacillus
barengoltzii) 		no annotation 5 MET A 429
GLY A 428
THR A 177
PHE A 478
GLY A 468
 None
 1.23A 3ag4A-5ww1A:
1.4
3ag4B-5ww1A:
undetectable
3ag4T-5ww1A:
undetectable		 3ag4A-5ww1A:
undetectable
3ag4B-5ww1A:
undetectable
3ag4T-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yb7 L-AMINO ACID
OXIDASE/MONOOXYGENAS
E

(Pseudomonas sp.
AIU 813) 		no annotation 5 GLY A 519
GLU A 518
THR A  16
THR A 252
PHE A  22
 None
 1.45A 3ag4A-5yb7A:
undetectable
3ag4B-5yb7A:
undetectable
3ag4T-5yb7A:
undetectable		 3ag4A-5yb7A:
undetectable
3ag4B-5yb7A:
undetectable
3ag4T-5yb7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z7r SHORT-CHAIN-ENOYL-CO
A HYDRATASE

(Clostridium
acetobutylicum) 		no annotation 5 GLY A 111
GLU A 134
THR A 140
PHE A  90
GLY A  86
 None
 0.93A 3ag4A-5z7rA:
undetectable
3ag4B-5z7rA:
undetectable
3ag4T-5z7rA:
undetectable		 3ag4A-5z7rA:
undetectable
3ag4B-5z7rA:
undetectable
3ag4T-5z7rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bn2 ACETYL-COA
ACETYLTRANSFERASE

(Elizabethkingia
anophelis) 		no annotation 5 MET A 156
GLY A 157
THR A 242
THR A 240
PHE A 288
 SCY  A  88 ( 4.8A)
SCY  A 159 ( 4.2A)
None
None
SCY  A 159 ( 4.6A)
 1.50A 3ag4A-6bn2A:
0.2
3ag4B-6bn2A:
undetectable
3ag4T-6bn2A:
undetectable		 3ag4A-6bn2A:
undetectable
3ag4B-6bn2A:
undetectable
3ag4T-6bn2A:
undetectable