SIMILAR PATTERNS OF AMINO ACIDS FOR 3AG3_O_CHDO229
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dgj | ALDEHYDEOXIDOREDUCTASE (Desulfovibriodesulfuricans) |
PF00111(Fer2)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2) | 5 | ARG A 535PHE A 423GLY A 424GLY A 699GLN A 657 | MCN A 914 ( 4.0A)MCN A 914 (-3.6A)2MO A 910 ( 3.5A)MCN A 914 (-4.6A)MCN A 914 (-3.7A) | 1.04A | 3ag3G-1dgjA:0.03ag3N-1dgjA:0.03ag3O-1dgjA:0.0 | 3ag3G-1dgjA:6.463ag3N-1dgjA:20.433ag3O-1dgjA:13.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k5s | PENICILLIN G ACYLASEBETA SUBUNIT (Escherichiacoli) |
PF01804(Penicil_amidase) | 5 | PHE B 531GLY B 532MET B 485GLU B 482THR B 481 | None | 1.18A | 3ag3G-1k5sB:0.03ag3N-1k5sB:2.73ag3O-1k5sB:0.0 | 3ag3G-1k5sB:12.503ag3N-1k5sB:20.533ag3O-1k5sB:17.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ahw | PUTATIVE ENZYME YDIF (Escherichiacoli) |
PF01144(CoA_trans) | 5 | GLY A 262GLY A 39GLN A 225GLU A 42THR A 45 | None | 1.13A | 3ag3G-2ahwA:0.03ag3N-2ahwA:0.03ag3O-2ahwA:0.0 | 3ag3G-2ahwA:10.233ag3N-2ahwA:21.783ag3O-2ahwA:16.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2buf | ACETYLGLUTAMATEKINASE (Pseudomonasaeruginosa) |
PF00696(AA_kinase) | 5 | ARG A 90GLY A 105GLY A 67GLN A 71GLU A 40 | NLG A1302 (-4.3A)NoneNLG A1302 (-3.3A)NoneNone | 1.35A | 3ag3G-2bufA:0.03ag3N-2bufA:0.03ag3O-2bufA:0.0 | 3ag3G-2bufA:14.043ag3N-2bufA:22.063ag3O-2bufA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ddt | SPHINGOMYELINPHOSPHODIESTERASE (Bacillus cereus) |
PF03372(Exo_endo_phos) | 5 | PHE A 133GLY A 149GLY A 102GLN A 116THR A 75 | None | 1.23A | 3ag3G-2ddtA:0.03ag3N-2ddtA:undetectable3ag3O-2ddtA:0.0 | 3ag3G-2ddtA:13.073ag3N-2ddtA:18.603ag3O-2ddtA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nlk | PROTEIN TYROSINEPHOSPHATASE,RECEPTOR TYPE, GVARIANT (FRAGMENT) (Homo sapiens) |
PF00102(Y_phosphatase) | 5 | MET A1029GLY A1030TRP A1026GLN A1104THR A1069 | None | 1.21A | 3ag3G-2nlkA:0.03ag3N-2nlkA:0.03ag3O-2nlkA:1.2 | 3ag3G-2nlkA:8.513ag3N-2nlkA:21.203ag3O-2nlkA:16.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pa5 | TYROSINE-PROTEINPHOSPHATASENON-RECEPTOR TYPE 9 (Homo sapiens) |
PF00102(Y_phosphatase) | 5 | ARG A 409GLY A 472TRP A 468GLN A 559THR A 524 | NoneNoneNone CL A 590 ( 4.8A)None | 1.40A | 3ag3G-2pa5A:0.03ag3N-2pa5A:0.03ag3O-2pa5A:0.0 | 3ag3G-2pa5A:12.873ag3N-2pa5A:17.343ag3O-2pa5A:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qua | EXTRACELLULAR LIPASE (Serratiamarcescens) |
no annotation | 5 | GLY A 174GLY A 181GLU A 112THR A 117THR A 113 | None | 1.41A | 3ag3G-2quaA:0.03ag3N-2quaA:0.03ag3O-2quaA:0.0 | 3ag3G-2quaA:9.093ag3N-2quaA:21.913ag3O-2quaA:15.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rhq | PHENYLALANYL-TRNASYNTHETASE ALPHACHAINPHENYLALANYL-TRNASYNTHETASE BETACHAIN (Staphylococcushaemolyticus;Staphylococcushaemolyticus) |
PF01409(tRNA-synt_2d)PF01588(tRNA_bind)PF03147(FDX-ACB)PF03483(B3_4)PF03484(B5) | 5 | ARG B 499GLY A 196GLY B 582GLN B 517GLU B 580 | None | 1.37A | 3ag3G-2rhqB:undetectable3ag3N-2rhqB:0.03ag3O-2rhqB:undetectable | 3ag3G-2rhqB:7.143ag3N-2rhqB:21.173ag3O-2rhqB:15.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wnb | - (Sus scrofa) |
PF00777(Glyco_transf_29) | 5 | ARG A 171PHE A 192GLY A 273GLY A 291THR A 328 | NoneNoneC5P A1344 (-3.2A)NoneNone | 1.48A | 3ag3G-2wnbA:undetectable3ag3N-2wnbA:undetectable3ag3O-2wnbA:undetectable | 3ag3G-2wnbA:14.733ag3N-2wnbA:17.883ag3O-2wnbA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xhy | 6-PHOSPHO-BETA-GLUCOSIDASE BGLA (Escherichiacoli) |
PF00232(Glyco_hydro_1) | 5 | GLY A 350GLY A 381TRP A 351THR A 435THR A 434 | NoneNoneNoneNoneSO4 A1481 (-4.0A) | 1.37A | 3ag3G-2xhyA:undetectable3ag3N-2xhyA:undetectable3ag3O-2xhyA:undetectable | 3ag3G-2xhyA:10.373ag3N-2xhyA:20.623ag3O-2xhyA:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bt7 | TRNA(URACIL-5-)-METHYLTRANSFERASE (Escherichiacoli) |
PF05958(tRNA_U5-meth_tr) | 5 | ARG A 230PHE A 224GLY A 222MET A 179GLU A 170 | None | 1.38A | 3ag3G-3bt7A:undetectable3ag3N-3bt7A:undetectable3ag3O-3bt7A:undetectable | 3ag3G-3bt7A:13.923ag3N-3bt7A:20.943ag3O-3bt7A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ce6 | ADENOSYLHOMOCYSTEINASE (Mycobacteriumtuberculosis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | ARG A 406PHE A 96GLY A 411GLY A 359THR A 269 | None | 1.28A | 3ag3G-3ce6A:undetectable3ag3N-3ce6A:undetectable3ag3O-3ce6A:undetectable | 3ag3G-3ce6A:12.003ag3N-3ce6A:22.593ag3O-3ce6A:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cvr | INVASION PLASMIDANTIGEN (Shigellaflexneri) |
PF12468(TTSSLRR)PF14496(NEL) | 5 | ARG A 375GLY A 484MET A 402GLY A 399THR A 392 | None | 1.42A | 3ag3G-3cvrA:undetectable3ag3N-3cvrA:undetectable3ag3O-3cvrA:undetectable | 3ag3G-3cvrA:9.073ag3N-3cvrA:22.783ag3O-3cvrA:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fah | ALDEHYDEOXIDOREDUCTASE (Desulfovibriogigas) |
PF00111(Fer2)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2) | 5 | ARG A 533PHE A 421GLY A 422GLY A 697GLN A 655 | PCD A 921 (-4.0A)PCD A 921 (-3.4A)PCD A 921 (-3.4A)GOL A 912 ( 3.1A)PCD A 921 (-3.6A) | 1.06A | 3ag3G-3fahA:undetectable3ag3N-3fahA:undetectable3ag3O-3fahA:undetectable | 3ag3G-3fahA:7.023ag3N-3fahA:21.153ag3O-3fahA:13.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgb | UNCHARACTERIZEDPROTEIN Q89ZH8_BACTN (Bacteroidesthetaiotaomicron) |
PF10282(Lactonase) | 5 | ARG A 112PHE A 104GLY A 83GLY A 153THR A 129 | None | 1.32A | 3ag3G-3fgbA:undetectable3ag3N-3fgbA:undetectable3ag3O-3fgbA:undetectable | 3ag3G-3fgbA:13.333ag3N-3fgbA:20.443ag3O-3fgbA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k55 | BETA-HEMOLYSIN (Staphylococcusaureus) |
PF03372(Exo_endo_phos) | 5 | PHE A 132GLY A 148GLY A 101GLN A 115THR A 75 | None | 1.25A | 3ag3G-3k55A:undetectable3ag3N-3k55A:undetectable3ag3O-3k55A:undetectable | 3ag3G-3k55A:14.193ag3N-3k55A:19.583ag3O-3k55A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s9b | VIPERA RUSSELLIPROTEINASE RVV-VGAMMA (Daboiasiamensis) |
PF00089(Trypsin) | 5 | ARG A 137ARG A 135PHE A 161GLY A 184GLY A 18 | None | 1.15A | 3ag3G-3s9bA:undetectable3ag3N-3s9bA:undetectable3ag3O-3s9bA:undetectable | 3ag3G-3s9bA:15.533ag3N-3s9bA:19.003ag3O-3s9bA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wy7 | 8-AMINO-7-OXONONANOATE SYNTHASE (Mycolicibacteriumsmegmatis) |
PF00155(Aminotran_1_2) | 5 | GLY A 94GLY A 214GLU A 201THR A 230THR A 231 | None | 1.38A | 3ag3G-3wy7A:undetectable3ag3N-3wy7A:undetectable3ag3O-3wy7A:undetectable | 3ag3G-3wy7A:12.933ag3N-3wy7A:21.193ag3O-3wy7A:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zyv | AOX3 (Mus musculus) |
PF00111(Fer2)PF00941(FAD_binding_5)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2)PF03450(CO_deh_flav_C) | 5 | ARG A 917PHE A 803GLY A 805GLY A1083GLN A1045 | MTE A3003 ( 2.9A)MTE A3003 (-4.1A)NoneMTE A3003 (-3.6A)MTE A3003 (-4.1A) | 1.38A | 3ag3G-3zyvA:undetectable3ag3N-3zyvA:0.33ag3O-3zyvA:undetectable | 3ag3G-3zyvA:4.983ag3N-3zyvA:18.193ag3O-3zyvA:10.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cgy | DNA TOPOISOMERASE3-ALPHA (Homo sapiens) |
PF01131(Topoisom_bac)PF01751(Toprim) | 5 | PHE A 559GLY A 552MET A 566GLY A 565THR A 544 | None | 1.37A | 3ag3G-4cgyA:undetectable3ag3N-4cgyA:1.83ag3O-4cgyA:undetectable | 3ag3G-4cgyA:9.363ag3N-4cgyA:20.213ag3O-4cgyA:12.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cu8 | GLYCOSIDE HYDROLASE2 (Streptococcuspneumoniae) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF16355(DUF4982) | 5 | PHE A 444GLY A 643GLY A 597GLU A 505THR A 482 | None | 1.35A | 3ag3G-4cu8A:undetectable3ag3N-4cu8A:undetectable3ag3O-4cu8A:undetectable | 3ag3G-4cu8A:7.933ag3N-4cu8A:20.583ag3O-4cu8A:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cu8 | GLYCOSIDE HYDROLASE2 (Streptococcuspneumoniae) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF16355(DUF4982) | 5 | PHE A 444GLY A 643GLY A 597THR A 482THR A 483 | None | 1.45A | 3ag3G-4cu8A:undetectable3ag3N-4cu8A:undetectable3ag3O-4cu8A:undetectable | 3ag3G-4cu8A:7.933ag3N-4cu8A:20.583ag3O-4cu8A:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g4i | 4-O-METHYL-GLUCURONOYL METHYLESTERASE (Thermothelomycesthermophila) |
no annotation | 5 | ARG A 214GLY A 218GLY A 238GLN A 235GLU A 305 | EDO A 506 (-3.6A)NoneNoneNoneNone | 1.40A | 3ag3G-4g4iA:undetectable3ag3N-4g4iA:undetectable3ag3O-4g4iA:undetectable | 3ag3G-4g4iA:12.003ag3N-4g4iA:21.153ag3O-4g4iA:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4htl | BETA-GLUCOSIDEKINASE (Listeriamonocytogenes) |
PF00480(ROK) | 5 | PHE A 153GLY A 133GLY A 242THR A 175THR A 176 | None | 1.45A | 3ag3G-4htlA:undetectable3ag3N-4htlA:undetectable3ag3O-4htlA:undetectable | 3ag3G-4htlA:14.633ag3N-4htlA:22.053ag3O-4htlA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j05 | PHOSPHATETRANSPORTER (Serendipitaindica) |
PF00083(Sugar_tr) | 5 | PHE A 493GLY A 492GLY A 315THR A 433THR A 434 | None | 1.20A | 3ag3G-4j05A:undetectable3ag3N-4j05A:0.23ag3O-4j05A:undetectable | 3ag3G-4j05A:10.883ag3N-4j05A:23.833ag3O-4j05A:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j9u | TRK SYSTEM POTASSIUMUPTAKE PROTEIN TRKH (Vibrioparahaemolyticus) |
PF02386(TrkH) | 5 | PHE A 466MET A 356GLY A 355THR A 110THR A 112 | None | 1.33A | 3ag3G-4j9uA:undetectable3ag3N-4j9uA:1.83ag3O-4j9uA:undetectable | 3ag3G-4j9uA:10.923ag3N-4j9uA:23.603ag3O-4j9uA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kkm | POLYPRENYLSYNTHETASE (Zymomonasmobilis) |
PF00348(polyprenyl_synt) | 5 | ARG A 50GLY A 190MET A 155GLY A 154GLN A 181 | None | 1.24A | 3ag3G-4kkmA:undetectable3ag3N-4kkmA:2.63ag3O-4kkmA:undetectable | 3ag3G-4kkmA:13.073ag3N-4kkmA:21.193ag3O-4kkmA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lls | GERANYLTRANSTRANSFERASE (Roseobacterdenitrificans) |
PF00348(polyprenyl_synt) | 5 | ARG A 44GLY A 184MET A 149GLY A 148GLN A 175 | IPE A 301 (-3.1A)NoneGST A 302 ( 4.1A)NoneNone | 1.18A | 3ag3G-4llsA:undetectable3ag3N-4llsA:1.93ag3O-4llsA:undetectable | 3ag3G-4llsA:14.293ag3N-4llsA:20.313ag3O-4llsA:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q1q | ADHESIN/INVASIN TIBAAUTOTRANSPORTER (Escherichiacoli) |
PF16168(AIDA) | 5 | ARG A 207GLY A 229GLN A 204THR A 215THR A 234 | 289 A 414 ( 3.6A)NoneNoneNoneNone | 1.37A | 3ag3G-4q1qA:undetectable3ag3N-4q1qA:undetectable3ag3O-4q1qA:undetectable | 3ag3G-4q1qA:12.163ag3N-4q1qA:21.893ag3O-4q1qA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qdg | PUTATIVE ADHESIN (Bacteroidesthetaiotaomicron) |
PF08842(Mfa2) | 5 | ARG A 253PHE A 119GLY A 153MET A 175THR A 67 | None | 1.36A | 3ag3G-4qdgA:undetectable3ag3N-4qdgA:undetectable3ag3O-4qdgA:undetectable | 3ag3G-4qdgA:13.973ag3N-4qdgA:20.493ag3O-4qdgA:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5epg | ALDEHYDE OXIDASE (Homo sapiens) |
PF00111(Fer2)PF00941(FAD_binding_5)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2)PF03450(CO_deh_flav_C) | 5 | ARG A 921PHE A 807GLY A 808GLY A1088GLN A1049 | MTE A3003 (-3.7A)MTE A3003 (-3.7A)MOS A3005 (-4.0A)MOS A3005 ( 3.4A)MTE A3003 (-4.4A) | 0.97A | 3ag3G-5epgA:undetectable3ag3N-5epgA:undetectable3ag3O-5epgA:undetectable | 3ag3G-5epgA:5.223ag3N-5epgA:16.153ag3O-5epgA:11.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gq0 | EPITHIOSPECIFIERPROTEIN (Arabidopsisthaliana) |
no annotation | 5 | ARG B 94PHE B 100GLY B 92GLY B 39THR B 73 | None | 1.20A | 3ag3G-5gq0B:undetectable3ag3N-5gq0B:undetectable3ag3O-5gq0B:undetectable | 3ag3G-5gq0B:12.463ag3N-5gq0B:20.153ag3O-5gq0B:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wn9 | SCFV 2D10 (Homo sapiens) |
no annotation | 5 | GLY H 97MET H 48GLY H 49GLN H 233THR H 235 | None | 1.12A | 3ag3G-5wn9H:undetectable3ag3N-5wn9H:undetectable3ag3O-5wn9H:undetectable | 3ag3G-5wn9H:undetectable3ag3N-5wn9H:undetectable3ag3O-5wn9H:undetectable |