SIMILAR PATTERNS OF AMINO ACIDS FOR 3AF3_A_PAUA314_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hra RETINOIC ACID
RECEPTOR

(Homo sapiens) 		PF00105
(zf-C4) 		4 PHE A  69
MET A  73
PHE A  32
PHE A  31
 None
 1.28A 3af3A-1hraA:
undetectable		 3af3A-1hraA:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k5s PENICILLIN G ACYLASE
BETA SUBUNIT

(Escherichia
coli) 		PF01804
(Penicil_amidase) 		4 TYR B  52
PHE B  50
PHE B 459
PHE B 460
 None
 1.36A 3af3A-1k5sB:
0.0		 3af3A-1k5sB:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nln ADENAIN

(Human
mastadenovirus
C) 		PF00770
(Peptidase_C5) 		4 ARG A  94
PHE A  32
PHE A  29
PHE A  58
 None
 1.37A 3af3A-1nlnA:
0.0		 3af3A-1nlnA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ven BETA-AMYLASE

(Bacillus cereus) 		PF00686
(CBM_20)
PF01373
(Glyco_hydro_14) 		4 TYR A  67
ARG A  70
PHE A  71
PHE A  31
 None
 1.43A 3af3A-1venA:
0.0		 3af3A-1venA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w61 B-CELL MITOGEN

(Trypanosoma
cruzi) 		PF05544
(Pro_racemase) 		4 ARG A  59
PHE A  46
MET A 377
PHE A 379
 None
 0.92A 3af3A-1w61A:
0.0		 3af3A-1w61A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wid DNA-BINDING PROTEIN
RAV1

(Arabidopsis
thaliana) 		PF02362
(B3) 		4 TYR A 242
PHE A 214
PHE A 188
PHE A 274
 None
 1.21A 3af3A-1widA:
undetectable		 3af3A-1widA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x0g ISCA

(Thermosynechococcus
elongatus) 		PF01521
(Fe-S_biosyn) 		4 ARG A  41
MET A 105
PHE A  92
PHE A  90
 FES  A 500 ( 4.9A)
None
None
None
 1.42A 3af3A-1x0gA:
undetectable		 3af3A-1x0gA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xrs D-LYSINE
5,6-AMINOMUTASE
ALPHA SUBUNIT

(Acetoanaerobium
sticklandii) 		PF09043
(Lys-AminoMut_A) 		4 TYR A 371
PHE A 340
MET A 342
PHE A 350
 None
 1.35A 3af3A-1xrsA:
0.0		 3af3A-1xrsA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zl6 BOTULINUM NEUROTOXIN
TYPE E

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		4 TYR A  72
ARG A  81
PHE A  82
PHE A 185
 None
 1.38A 3af3A-1zl6A:
0.0		 3af3A-1zl6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zsw GLYOXALASE FAMILY
PROTEIN

(Bacillus cereus) 		PF00903
(Glyoxalase) 		4 ARG A 243
PHE A 178
PHE A 261
PHE A 269
 None
 1.24A 3af3A-1zswA:
0.0		 3af3A-1zswA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e0w GAMMA-GLUTAMYLTRANSP
EPTIDASE

(Escherichia
coli) 		PF01019
(G_glu_transpept) 		4 TYR A 501
PHE A 317
PHE A 529
PHE A 514
 None
 1.46A 3af3A-2e0wA:
undetectable		 3af3A-2e0wA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hma PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE

(Streptococcus
pneumoniae) 		PF03054
(tRNA_Me_trans) 		4 ARG A 297
PHE A 295
MET A 299
PHE A 303
 None
 0.98A 3af3A-2hmaA:
undetectable		 3af3A-2hmaA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2im5 NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE

(Porphyromonas
gingivalis) 		PF04095
(NAPRTase) 		4 TYR A 290
PHE A 261
MET A 258
PHE A 257
 None
 1.25A 3af3A-2im5A:
undetectable		 3af3A-2im5A:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mqs MATRIX
METALLOPROTEINASE-14

(Homo sapiens) 		PF00045
(Hemopexin) 		4 TYR A 435
PHE A 430
PHE A 477
PHE A 486
 None
 1.49A 3af3A-2mqsA:
undetectable		 3af3A-2mqsA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vha PERIPLASMIC BINDING
TRANSPORT PROTEIN

(Shigella
flexneri) 		PF00497
(SBP_bac_3) 		4 TYR A 211
PHE A 108
PHE A 247
PHE A 260
 GLU  A1280 (-4.7A)
None
None
None
 1.06A 3af3A-2vhaA:
undetectable		 3af3A-2vhaA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x2i ALPHA-1,4-GLUCAN
LYASE ISOZYME 1

(Gracilariopsis
lemaneiformis) 		PF01055
(Glyco_hydro_31) 		4 ARG A 187
PHE A  63
PHE A  93
PHE A 322
 None
 1.38A 3af3A-2x2iA:
undetectable		 3af3A-2x2iA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA

(Saccharomyces
cerevisiae) 		PF11988
(Dsl1_N) 		4 TYR A 179
PHE A 174
MET A 172
PHE A 171
 None
 1.30A 3af3A-3etvA:
undetectable		 3af3A-3etvA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN

(Porcine
torovirus) 		PF02710
(Hema_HEFG)
PF03996
(Hema_esterase) 		4 ARG A 161
MET A 221
PHE A 219
PHE A 228
 SIO  A1001 (-3.4A)
SIO  A1001 (-3.7A)
SIO  A1001 (-3.5A)
None
 1.48A 3af3A-3i1lA:
undetectable		 3af3A-3i1lA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i7f ASPARTYL-TRNA
SYNTHETASE

(Entamoeba
histolytica) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		4 ARG A 384
PHE A 386
PHE A 431
PHE A 354
 None
 1.39A 3af3A-3i7fA:
undetectable		 3af3A-3i7fA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ilv GLUTAMINE-DEPENDENT
NAD(+) SYNTHETASE

(Cytophaga
hutchinsonii) 		PF00795
(CN_hydrolase)
PF02540
(NAD_synthase) 		4 TYR A 606
ARG A 586
PHE A 575
PHE A 576
 None
 1.22A 3af3A-3ilvA:
undetectable		 3af3A-3ilvA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kv0 HET-C2

(Podospora
anserina) 		PF08718
(GLTP) 		4 PHE A 135
MET A 159
PHE A  60
PHE A  52
 None
None
None
MLY  A  64 ( 4.5A)
 1.32A 3af3A-3kv0A:
undetectable		 3af3A-3kv0A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l4b TRKA K+ CHANNEL
PROTIEN TM1088A
TRKA K+ CHANNEL
PROTIEN TM1088B

(Thermotoga
maritima;
Thermotoga
maritima) 		PF02254
(TrkA_N)
PF02080
(TrkA_C)
PF02254
(TrkA_N) 		4 PHE A 115
MET A  91
PHE A  87
PHE C  81
 None
 1.40A 3af3A-3l4bA:
undetectable		 3af3A-3l4bA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3naf CALCIUM-ACTIVATED
POTASSIUM CHANNEL
SUBUNIT
ALPHA-1,CALCIUM-ACTI
VATED POTASSIUM
CHANNEL SUBUNIT
ALPHA-1,CALCIUM-ACTI
VATED POTASSIUM
CHANNEL SUBUNIT
ALPHA-1

(Homo sapiens) 		PF03493
(BK_channel_a) 		4 TYR A 463
ARG A 735
MET A 739
PHE A 692
 None
 1.07A 3af3A-3nafA:
undetectable		 3af3A-3nafA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3owt DNA-BINDING PROTEIN
RAP1

(Saccharomyces
cerevisiae) 		PF11626
(Rap1_C) 		4 PHE A 769
MET A 717
PHE A 716
PHE A 707
 None
 1.47A 3af3A-3owtA:
undetectable		 3af3A-3owtA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3poc ALPHA-GLUCOSIDASE

(Blautia obeum) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		4 ARG A 178
PHE A 177
PHE A 214
PHE A 217
 None
 1.33A 3af3A-3pocA:
undetectable		 3af3A-3pocA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3quc INORGANIC
PYROPHOSPHATASE

(Bacteroides
thetaiotaomicron) 		PF13419
(HAD_2) 		4 PHE A 128
MET A 131
PHE A 132
PHE A  10
 None
 1.37A 3af3A-3qucA:
undetectable		 3af3A-3qucA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rac HISTIDINE-TRNA
LIGASE

(Alicyclobacillus
acidocaldarius) 		PF13393
(tRNA-synt_His) 		4 TYR A 333
ARG A 332
PHE A 316
PHE A 349
 LMR  A 401 (-4.1A)
None
None
None
 1.23A 3af3A-3racA:
undetectable		 3af3A-3racA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3smv S-(-)-AZETIDINE-2-CA
RBOXYLATE HYDROLASE

(Pseudomonas sp.
AC2) 		PF13419
(HAD_2) 		4 TYR A 115
MET A 230
PHE A 224
PHE A 222
 None
 1.36A 3af3A-3smvA:
undetectable		 3af3A-3smvA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN

(Streptococcus
pyogenes) 		PF09704
(Cas_Cas5d) 		4 TYR A   2
ARG A   3
PHE A 101
PHE A   7
 None
 1.18A 3af3A-3vzhA:
undetectable		 3af3A-3vzhA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zvu ABSCISIC ACID
RECEPTOR PYR1

(Arabidopsis
thaliana) 		PF10604
(Polyketide_cyc2) 		4 ARG A  50
PHE A  52
MET A  73
PHE A  71
 None
 1.47A 3af3A-3zvuA:
undetectable		 3af3A-3zvuA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bjt DNA-BINDING PROTEIN
RAP1

(Saccharomyces
cerevisiae) 		PF11626
(Rap1_C) 		4 PHE A 769
MET A 717
PHE A 716
PHE A 707
 None
 1.43A 3af3A-4bjtA:
undetectable		 3af3A-4bjtA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4itm TETRAACYLDISACCHARID
E 4'-KINASE

(Aquifex
aeolicus) 		PF02606
(LpxK) 		4 TYR A 275
PHE A 232
MET A 256
PHE A 258
 None
 1.33A 3af3A-4itmA:
4.3		 3af3A-4itmA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iw7 8-AMINO-7-OXONONANOA
TE SYNTHASE

(Francisella
tularensis) 		PF00155
(Aminotran_1_2) 		4 ARG A 198
PHE A  81
PHE A 190
PHE A 222
 None
 1.49A 3af3A-4iw7A:
1.9		 3af3A-4iw7A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n54 INOSITOL
DEHYDROGENASE

(Lactobacillus
casei) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 TYR A 247
ARG A 290
PHE A 287
PHE A 295
 2H3  A 402 (-4.5A)
None
NAI  A 401 ( 3.7A)
NAI  A 401 (-4.9A)
 0.97A 3af3A-4n54A:
undetectable		 3af3A-4n54A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4omg GERANYLGERANYL
DIPHOSPHATE CYCLASE

(Streptomyces
melanosporofaciens) 		no annotation 4 ARG A  27
PHE A  29
PHE A 253
PHE A 222
 None
 1.40A 3af3A-4omgA:
undetectable		 3af3A-4omgA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Alicyclobacillus
acidocaldarius) 		PF13416
(SBP_bac_8) 		4 PHE A 428
MET A 410
PHE A 407
PHE A 211
 None
 1.25A 3af3A-4ovjA:
undetectable		 3af3A-4ovjA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qhx UNCHARACTERIZED
PROTEIN

(Bacteroides
caccae) 		PF11958
(DUF3472)
PF16871
(DUF5077) 		4 TYR A 314
PHE A 197
PHE A 216
PHE A 202
 None
 1.50A 3af3A-4qhxA:
undetectable		 3af3A-4qhxA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r0j UNCHARACTERIZED
PROTEIN

(Streptococcus
mutans) 		PF09704
(Cas_Cas5d) 		4 TYR A   4
ARG A   5
PHE A 103
PHE A   9
 None
 1.22A 3af3A-4r0jA:
undetectable		 3af3A-4r0jA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgp CSM6_III-A

(Streptococcus
mutans) 		PF09659
(Cas_Csm6) 		4 TYR A  16
ARG A  43
MET A  84
PHE A 240
 None
 1.38A 3af3A-4rgpA:
undetectable		 3af3A-4rgpA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd9 NISIN BIOSYNTHESIS
PROTEIN NISB

(Lactococcus
lactis) 		PF04738
(Lant_dehydr_N)
PF14028
(Lant_dehydr_C) 		4 TYR A 979
PHE A 889
PHE A 879
PHE A 878
 None
 1.44A 3af3A-4wd9A:
undetectable		 3af3A-4wd9A:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wp0 KYNURENINE--OXOGLUTA
RATE TRANSAMINASE 1

(Homo sapiens) 		PF00155
(Aminotran_1_2) 		4 ARG A 300
PHE A 306
PHE A  79
PHE A  80
 None
 1.29A 3af3A-4wp0A:
undetectable		 3af3A-4wp0A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wx6 PROTEASE

(Human
mastadenovirus
D) 		PF00770
(Peptidase_C5) 		4 ARG A  94
PHE A  32
PHE A  29
PHE A  58
 None
 1.38A 3af3A-4wx6A:
undetectable		 3af3A-4wx6A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b8i CALCINEURIN SUBUNIT
B, VARIANT

(Coccidioides
immitis) 		PF13202
(EF-hand_5)
PF13499
(EF-hand_7) 		4 PHE B  43
MET B  58
PHE B  62
PHE B  75
 None
 1.12A 3af3A-5b8iB:
undetectable		 3af3A-5b8iB:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c91 E3 UBIQUITIN-PROTEIN
LIGASE NEDD4

(Homo sapiens) 		PF00632
(HECT) 		4 TYR A 661
PHE A 660
PHE A 608
PHE A 601
 None
 1.46A 3af3A-5c91A:
undetectable		 3af3A-5c91A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c92 KELCH
DOMAIN-CONTAINING
PROTEIN

(Colletotrichum
graminicola) 		PF01344
(Kelch_1)
PF09118
(DUF1929) 		4 TYR A 334
MET A 173
PHE A 174
PHE A 138
 CU1  A 503 (-4.3A)
None
None
None
 1.15A 3af3A-5c92A:
undetectable		 3af3A-5c92A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idi 1,4-BETA-D-GLUCAN
GLUCOHYDROLASE

(Thermotoga
neapolitana) 		PF00232
(Glyco_hydro_1) 		4 PHE A 243
MET A 240
PHE A 239
PHE A 265
 None
 1.36A 3af3A-5idiA:
undetectable		 3af3A-5idiA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mmx CSPYL1_ABA

(Citrus sinensis) 		no annotation 4 ARG B  79
PHE B  81
MET B 102
PHE B 100
 None
 1.31A 3af3A-5mmxB:
undetectable		 3af3A-5mmxB:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mob SLPYL1_ABA

(Solanum
lycopersicum) 		PF10604
(Polyketide_cyc2) 		4 ARG A  87
PHE A  89
MET A 110
PHE A 108
 None
 1.45A 3af3A-5mobA:
undetectable		 3af3A-5mobA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xbp 3NT OXYGENASE ALPHA
SUBUNIT

(Diaphorobacter
sp. DS2) 		PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A) 		4 TYR A 147
PHE A 145
PHE A 172
PHE A 304
 None
 1.49A 3af3A-5xbpA:
undetectable		 3af3A-5xbpA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y5p WSV112

(White spot
syndrome virus) 		no annotation 4 TYR A  91
ARG A  92
MET A  10
PHE A  12
 DUR  A 501 (-3.3A)
None
None
None
 1.42A 3af3A-5y5pA:
undetectable		 3af3A-5y5pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6emo -

(-) 		no annotation 4 ARG A 480
PHE A 479
PHE A 476
PHE A 406
 None
 0.91A 3af3A-6emoA:
undetectable		 3af3A-6emoA:
undetectable