SIMILAR PATTERNS OF AMINO ACIDS FOR 3ADS_A_IMNA2_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1an7 | RIBOSOMAL PROTEIN S8 (Thermusthermophilus) |
PF00410(Ribosomal_S8) | 4 | ILE A 83TYR A 20LEU A 39PHE A 44 | None | 0.90A | 3adsA-1an7A:0.0 | 3adsA-1an7A:15.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1axn | ANNEXIN III (Homo sapiens) |
PF00191(Annexin) | 4 | ILE A 28ILE A 314LEU A 69MET A 85 | None | 0.87A | 3adsA-1axnA:undetectable | 3adsA-1axnA:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c7k | ZINC ENDOPROTEASE (Streptomycescaespitosus) |
PF02031(Peptidase_M7) | 4 | ILE A 65TYR A 95LEU A 67PHE A 66 | None | 1.12A | 3adsA-1c7kA:undetectable | 3adsA-1c7kA:14.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f3l | PROTEIN ARGININEMETHYLTRANSFERASEPRMT3 (Rattusnorvegicus) |
PF06325(PrmA) | 4 | ILE A 416ILE A 359TYR A 455LEU A 364 | None | 0.89A | 3adsA-1f3lA:0.0 | 3adsA-1f3lA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hkw | DIAMINOPIMELATEDECARBOXYLASE (Mycobacteriumtuberculosis) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 4 | ILE A 26ILE A 261TYR A 263LEU A 31 | None | 1.13A | 3adsA-1hkwA:0.0 | 3adsA-1hkwA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lqw | PEPTIDE DEFORMYLASEPDF1 (Staphylococcusaureus) |
PF01327(Pep_deformylase) | 4 | ILE A 66ILE A 156LEU A 2PHE A 40 | None | 1.19A | 3adsA-1lqwA:undetectable | 3adsA-1lqwA:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ls4 | APOLIPOPHORIN-III (Locustamigratoria) |
no annotation | 4 | ILE A 118ILE A 21LEU A 77PHE A 80 | None | 0.77A | 3adsA-1ls4A:undetectable | 3adsA-1ls4A:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mwo | ALPHA AMYLASE (Pyrococcuswoesei) |
PF00128(Alpha-amylase)PF09154(DUF1939) | 4 | ILE A 30ILE A 327LEU A 47MET A 13 | None | 0.99A | 3adsA-1mwoA:0.0 | 3adsA-1mwoA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ogo | DEXTRANASE (Talaromycesminioluteus) |
PF03718(Glyco_hydro_49)PF17433(Glyco_hydro_49N) | 4 | ILE X 280ILE X 358TYR X 381LEU X 296 | None | 1.17A | 3adsA-1ogoX:0.0 | 3adsA-1ogoX:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q1n | HYPOTHETICALZINC-TYPE ALCOHOLDEHYDROGENASE-LIKEPROTEIN IN PRE5-FET4INTERGENIC REGION (Saccharomycescerevisiae) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | ILE A 296ILE A 185LEU A 286MET A 262 | None | 1.16A | 3adsA-1q1nA:0.0 | 3adsA-1q1nA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qaf | PROTEIN (COPPERAMINE OXIDASE) (Escherichiacoli) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3)PF07833(Cu_amine_oxidN1) | 4 | ILE A 605ILE A 473LEU A 638PHE A 580 | None | 0.96A | 3adsA-1qafA:undetectable | 3adsA-1qafA:17.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rif | DNA HELICASE UVSW (Escherichiavirus T4) |
PF04851(ResIII) | 4 | ILE A 144ILE A 188LEU A 133MET A 230 | None | 1.00A | 3adsA-1rifA:undetectable | 3adsA-1rifA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uaa | PROTEIN(ATP-DEPENDENT DNAHELICASE REP.) (Escherichiacoli) |
PF00580(UvrD-helicase)PF13361(UvrD_C) | 4 | ILE A 50TYR A 45LEU A 268PHE A 265 | None | 1.17A | 3adsA-1uaaA:undetectable | 3adsA-1uaaA:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ga8 | HYPOTHETICAL 39.9KDA PROTEIN (Saccharomycescerevisiae) |
PF07728(AAA_5) | 4 | ILE A 350ILE A 342TYR A 281LEU A 7 | None | 1.14A | 3adsA-2ga8A:undetectable | 3adsA-2ga8A:23.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gko | SUBTILISINMICROBIAL SERINEPROTEINASES (Bacillussubtilis) |
PF00082(Peptidase_S8) | 4 | ILE A 163ILE A 10TYR A 14LEU A 161 | None | 0.98A | 3adsA-2gkoA:undetectable | 3adsA-2gkoA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gmy | HYPOTHETICAL PROTEINATU0492 (Agrobacteriumfabrum) |
PF02627(CMD) | 4 | ILE A 123ILE A 45LEU A 30PHE A 34 | None | 0.90A | 3adsA-2gmyA:undetectable | 3adsA-2gmyA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hpi | DNA POLYMERASE IIIALPHA SUBUNIT (Thermusaquaticus) |
PF02811(PHP)PF07733(DNA_pol3_alpha)PF14579(HHH_6) | 4 | ILE A 394ILE A 410TYR A 409PHE A 399 | None | 1.16A | 3adsA-2hpiA:undetectable | 3adsA-2hpiA:13.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j0w | LYSINE-SENSITIVEASPARTOKINASE 3 (Escherichiacoli) |
PF00696(AA_kinase)PF01842(ACT) | 4 | ILE A 180ILE A 44LEU A 130MET A 20 | None | 1.17A | 3adsA-2j0wA:undetectable | 3adsA-2j0wA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nad | NAD-DEPENDENTFORMATEDEHYDROGENASE (Pseudomonas sp.101) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 4 | ILE A 158LEU A 210PHE A 213MET A 192 | None | 0.64A | 3adsA-2nadA:undetectable | 3adsA-2nadA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nlx | XYLULOSE KINASE (Escherichiacoli) |
PF00370(FGGY_N)PF02782(FGGY_C) | 4 | ILE A 393ILE A 385LEU A 449MET A 243 | None | 1.10A | 3adsA-2nlxA:undetectable | 3adsA-2nlxA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nrj | HBL B PROTEIN (Bacillus cereus) |
PF05791(Bacillus_HBL) | 4 | ILE A 259ILE A 270LEU A 43MET A 36 | None | 0.95A | 3adsA-2nrjA:undetectable | 3adsA-2nrjA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oca | ATP-DEPENDENT DNAHELICASE UVSW (Escherichiavirus T4) |
PF00271(Helicase_C)PF04851(ResIII) | 4 | ILE A 144ILE A 188LEU A 133MET A 230 | None | 0.98A | 3adsA-2ocaA:undetectable | 3adsA-2ocaA:21.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2p54 | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR ALPHA (Homo sapiens) |
PF00104(Hormone_recep) | 5 | ILE A 272ILE A 317LEU A 347PHE A 351MET A 355 | 735 A 469 ( 4.2A)735 A 469 ( 4.8A)NoneNone735 A 469 (-2.9A) | 0.38A | 3adsA-2p54A:37.1 | 3adsA-2p54A:61.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q0t | PUTATIVEGAMMA-CARBOXYMUCONOLACTONE DECARBOXYLASESUBUNIT (Paraburkholderiaxenovorans) |
PF02627(CMD) | 4 | ILE A 63ILE A 236TYR A 42LEU A 55 | None | 0.92A | 3adsA-2q0tA:undetectable | 3adsA-2q0tA:24.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q88 | PUTATIVE ABCTRANSPORTER AMINOACID-BINDING PROTEIN (Sinorhizobiummeliloti) |
PF00497(SBP_bac_3) | 4 | ILE A 233ILE A 18LEU A 224PHE A 230 | None | 1.15A | 3adsA-2q88A:undetectable | 3adsA-2q88A:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qp2 | UNKNOWN PROTEIN (Photorhabduslaumondii) |
PF01823(MACPF) | 4 | ILE A 325LEU A 64PHE A 202MET A 61 | None | 1.13A | 3adsA-2qp2A:undetectable | 3adsA-2qp2A:22.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qsr | TRANSCRIPTION-REPAIRCOUPLING FACTOR (Streptococcuspneumoniae) |
PF03461(TRCF) | 4 | ILE A1073ILE A1027TYR A1026LEU A1147 | None | 0.74A | 3adsA-2qsrA:undetectable | 3adsA-2qsrA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qv2 | INOSITOLPOLYPHOSPHATE5-PHOSPHATASE OCRL-1 (Homo sapiens) |
PF00620(RhoGAP) | 4 | ILE A 301ILE A 244LEU A 288MET A 281 | ILE A 301 ( 0.7A)ILE A 244 ( 0.7A)LEU A 288 ( 0.6A)MET A 281 ( 0.0A) | 1.01A | 3adsA-2qv2A:undetectable | 3adsA-2qv2A:23.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qwu | INTRACELLULAR GROWTHLOCUS, SUBUNIT C (Francisellatularensis) |
PF11550(IglC) | 4 | ILE A 89ILE A 7LEU A 91MET A 36 | None | 1.05A | 3adsA-2qwuA:undetectable | 3adsA-2qwuA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uwb | CELLULASE (Tropaeolummajus) |
PF00722(Glyco_hydro_16)PF06955(XET_C) | 4 | ILE A 95ILE A 66TYR A 205LEU A 173 | None | 1.03A | 3adsA-2uwbA:undetectable | 3adsA-2uwbA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vpn | PERIPLASMICSUBSTRATE BINDINGPROTEIN (Halomonaselongata) |
PF03480(DctP) | 4 | ILE A 79ILE A 274LEU A 300PHE A 303 | None | 1.06A | 3adsA-2vpnA:undetectable | 3adsA-2vpnA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vxk | GLUCOSAMINE6-PHOSPHATEACETYLTRANSFERASE (Aspergillusfumigatus) |
PF00583(Acetyltransf_1) | 4 | ILE A 147ILE A 106TYR A 62LEU A 164 | NoneNoneNone16G A1191 ( 3.9A) | 1.04A | 3adsA-2vxkA:undetectable | 3adsA-2vxkA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w5s | PROCESSED GLYCEROLPHOSPHATELIPOTEICHOIC ACIDSYNTHASE (Staphylococcusaureus) |
PF00884(Sulfatase) | 4 | ILE A 252ILE A 365TYR A 360LEU A 254 | None | 1.17A | 3adsA-2w5sA:undetectable | 3adsA-2w5sA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yg6 | PUTRESCINE OXIDASE (Rhodococcuserythropolis) |
PF01593(Amino_oxidase) | 4 | ILE A 169LEU A 199PHE A 168MET A 122 | None | 0.91A | 3adsA-2yg6A:undetectable | 3adsA-2yg6A:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yij | PHOSPHOLIPASEA1-IIGAMMA (Arabidopsisthaliana) |
PF01764(Lipase_3) | 4 | ILE A 193ILE A 232LEU A 114PHE A 113 | None | 1.09A | 3adsA-2yijA:undetectable | 3adsA-2yijA:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yxb | COENZYMEB12-DEPENDENT MUTASE (Aeropyrumpernix) |
PF02310(B12-binding) | 4 | ILE A 75ILE A 111LEU A 95MET A 88 | None | 0.85A | 3adsA-2yxbA:undetectable | 3adsA-2yxbA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yzw | ADP-RIBOSYLGLYCOHYDROLASE (Thermusthermophilus) |
PF03747(ADP_ribosyl_GH) | 4 | ILE A 272LEU A 50PHE A 54MET A 42 | None | 0.99A | 3adsA-2yzwA:undetectable | 3adsA-2yzwA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a64 | CELLOBIOHYDROLASE (Coprinopsiscinerea) |
PF01341(Glyco_hydro_6) | 4 | ILE A 191ILE A 129TYR A 125LEU A 152 | None | 0.90A | 3adsA-3a64A:undetectable | 3adsA-3a64A:18.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3b0q | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 6 | ILE A 281ILE A 326TYR A 327LEU A 356PHE A 360MET A 364 | MC5 A 1 ( 4.8A)MC5 A 1 ( 4.9A)NoneNoneNoneMC5 A 1 (-3.7A) | 0.37A | 3adsA-3b0qA:42.0 | 3adsA-3b0qA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3be7 | ZN-DEPENDENTARGININECARBOXYPEPTIDASE (unidentified) |
PF01979(Amidohydro_1) | 4 | ILE A 355ILE A 16LEU A 130MET A 59 | None | 0.93A | 3adsA-3be7A:undetectable | 3adsA-3be7A:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d1l | PUTATIVE NADPOXIDOREDUCTASEBF3122 (Bacteroidesfragilis) |
PF03807(F420_oxidored)PF10728(DUF2520) | 4 | ILE A 13ILE A 152LEU A 73PHE A 78 | None | 1.08A | 3adsA-3d1lA:undetectable | 3adsA-3d1lA:24.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dls | PASDOMAIN-CONTAININGSERINE/THREONINE-PROTEIN KINASE (Homo sapiens) |
PF00069(Pkinase) | 4 | ILE A1108ILE A1065LEU A1196PHE A1109 | NoneADP A 1 (-4.0A)NoneNone | 1.14A | 3adsA-3dlsA:undetectable | 3adsA-3dlsA:20.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3dzu | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR GAMMA (Homo sapiens) |
PF00104(Hormone_recep)PF00105(zf-C4) | 5 | ILE D 281ILE D 326LEU D 356PHE D 360MET D 364 | PLB D 701 (-4.6A)PLB D 701 ( 4.5A)NoneNonePLB D 701 ( 4.8A) | 0.54A | 3adsA-3dzuD:37.2 | 3adsA-3dzuD:94.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3dzu | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR GAMMA (Homo sapiens) |
PF00104(Hormone_recep)PF00105(zf-C4) | 5 | ILE D 326TYR D 327LEU D 356PHE D 360MET D 364 | PLB D 701 ( 4.5A)NoneNoneNonePLB D 701 ( 4.8A) | 0.62A | 3adsA-3dzuD:37.2 | 3adsA-3dzuD:94.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ian | CHITINASE (Lactococcuslactis) |
PF00704(Glyco_hydro_18) | 4 | ILE A 281ILE A 214TYR A 210LEU A 283 | None | 0.72A | 3adsA-3ianA:undetectable | 3adsA-3ianA:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ilr | HEPARIN LYASE I (Bacteroidesthetaiotaomicron) |
PF14099(Polysacc_lyase) | 4 | ILE A 240ILE A 135TYR A 368LEU A 229 | None | 1.12A | 3adsA-3ilrA:undetectable | 3adsA-3ilrA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k7d | GLUTAMATE-AMMONIA-LIGASEADENYLYLTRANSFERASE (Escherichiacoli) |
PF03710(GlnE)PF08335(GlnD_UR_UTase) | 4 | ILE A 484ILE A 496LEU A 455MET A 508 | None | 1.16A | 3adsA-3k7dA:undetectable | 3adsA-3k7dA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3omn | CYTOCHROME COXIDASE, AA3 TYPE,SUBUNIT I (Rhodobactersphaeroides) |
PF00115(COX1) | 4 | ILE A 232ILE A 310PHE A 233MET A 320 | None | 1.16A | 3adsA-3omnA:undetectable | 3adsA-3omnA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ozy | PUTATIVE MANDELATERACEMASE (Bordetellabronchiseptica) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ILE A 284ILE A 309TYR A 344LEU A 130 | None | 1.11A | 3adsA-3ozyA:undetectable | 3adsA-3ozyA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qw3 | OROTIDINE-5-PHOSPHATEDECARBOXYLASE/OROTATEPHOSPHORIBOSYLTRANSFERASE, PUTATIVE(OMPDCASE-OPRTASE,PUTATIVE) (Leishmaniainfantum) |
PF00215(OMPdecase) | 4 | ILE A 248ILE A 77TYR A 48LEU A 208 | None | 1.05A | 3adsA-3qw3A:undetectable | 3adsA-3qw3A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qw4 | UMP SYNTHASE (Leishmaniadonovani) |
PF00156(Pribosyltran)PF00215(OMPdecase) | 4 | ILE B 248ILE B 77TYR B 48LEU B 208 | None | 1.03A | 3adsA-3qw4B:undetectable | 3adsA-3qw4B:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rkx | BIOTIN-[ACETYL-COA-CARBOXYLASE] LIGASE (Staphylococcusaureus) |
PF03099(BPL_LplA_LipB)PF08279(HTH_11) | 4 | ILE A 71ILE A 111TYR A 88LEU A 9 | None | 1.10A | 3adsA-3rkxA:undetectable | 3adsA-3rkxA:25.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s5u | PUTATIVEUNCHARACTERIZEDPROTEIN (Enterococcusfaecalis) |
PF09711(Cas_Csn2) | 4 | ILE A 35ILE A 65TYR A 172LEU A 31 | None | 1.16A | 3adsA-3s5uA:undetectable | 3adsA-3s5uA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tlm | SARCOPLASMIC/ENDOPLASMIC RETICULUMCALCIUM ATPASE 1 (Bos taurus) |
PF00122(E1-E2_ATPase)PF00689(Cation_ATPase_C)PF00690(Cation_ATPase_N)PF08282(Hydrolase_3)PF13246(Cation_ATPase) | 4 | ILE A 742ILE A 752LEU A 734MET A 326 | None | 1.17A | 3adsA-3tlmA:undetectable | 3adsA-3tlmA:16.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vz0 | PUTATIVENAD-DEPENDENTALDEHYDEDEHYDROGENASE (Gluconobacteroxydans) |
PF00171(Aldedh) | 4 | ILE A 201LEU A 20PHE A 186MET A 26 | None | 1.14A | 3adsA-3vz0A:undetectable | 3adsA-3vz0A:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wwp | (S)-HYDROXYNITRILELYASE (Baliospermummontanum) |
PF00561(Abhydrolase_1) | 4 | ILE A 84ILE A 65TYR A 93LEU A 183 | None | 1.07A | 3adsA-3wwpA:undetectable | 3adsA-3wwpA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bfr | PHOSPHATIDYLINOSITOL4,5-BISPHOSPHATE3-KINASE CATALYTIC SSUBUNIT BETA ISOFORM (Mus musculus) |
PF00454(PI3_PI4_kinase)PF00613(PI3Ka)PF00792(PI3K_C2)PF00794(PI3K_rbd) | 4 | ILE A 919ILE A 935LEU A 927PHE A 928 | None | 0.78A | 3adsA-4bfrA:undetectable | 3adsA-4bfrA:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bxw | FACTOR XA (Pseudonajatextilis) |
PF00089(Trypsin)PF14670(FXa_inhibition) | 4 | ILE A 275ILE A 408TYR A 243LEU A 237 | None | 1.15A | 3adsA-4bxwA:undetectable | 3adsA-4bxwA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cdb | LISTERIOLYSIN O (Listeriamonocytogenes) |
PF01289(Thiol_cytolysin)PF17440(Thiol_cytolys_C) | 4 | ILE A 249ILE A 108TYR A 406LEU A 306 | None NA A1536 ( 4.4A) NA A1536 (-4.5A)None | 1.10A | 3adsA-4cdbA:undetectable | 3adsA-4cdbA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fbq | DNA REPAIR ANDTELOMERE MAINTENANCEPROTEIN NBS1,DNAREPAIR PROTEIN RAD32CHIMERIC PROTEIN (Schizosaccharomycespombe) |
PF00149(Metallophos)PF04152(Mre11_DNA_bind) | 4 | ILE A1114TYR A1116LEU A1292MET A1059 | None | 1.16A | 3adsA-4fbqA:undetectable | 3adsA-4fbqA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jdy | PYRIDOXALBIOSYNTHESIS LYASEPDXS (Mycobacteriumtuberculosis) |
PF01680(SOR_SNZ) | 4 | ILE A 151ILE A 220LEU A 210MET A 169 | None | 1.13A | 3adsA-4jdyA:undetectable | 3adsA-4jdyA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lej | VICILIN (Pinuskoraiensis) |
PF00190(Cupin_1) | 4 | ILE A 177TYR A 195LEU A 175MET A 117 | NoneNoneNoneGOL A 503 ( 4.9A) | 0.73A | 3adsA-4lejA:undetectable | 3adsA-4lejA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mb2 | PHOSPHOPANTOTHENATESYNTHETASE (Thermococcusonnurineus) |
PF02006(PPS_PS) | 4 | ILE A 47ILE A 254LEU A 182PHE A 43 | NoneNoneATP A 301 (-3.8A)None | 0.96A | 3adsA-4mb2A:undetectable | 3adsA-4mb2A:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nu7 | RIBULOSE-PHOSPHATE3-EPIMERASE (Toxoplasmagondii) |
PF00834(Ribul_P_3_epim) | 4 | ILE A 92ILE A 8LEU A 72PHE A 94 | None | 0.83A | 3adsA-4nu7A:undetectable | 3adsA-4nu7A:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o4f | INOSITOLHEXAKISPHOSPHATEKINASE (Entamoebahistolytica) |
PF03770(IPK) | 4 | ILE A 169ILE A 142LEU A 100MET A 138 | None | 1.06A | 3adsA-4o4fA:undetectable | 3adsA-4o4fA:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p0v | FARNESYLPYROPHOSPHATESYNTHASE (Homo sapiens) |
PF00348(polyprenyl_synt) | 4 | ILE A 210ILE A 139LEU A 232PHE A 206 | None | 1.18A | 3adsA-4p0vA:undetectable | 3adsA-4p0vA:25.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pqj | PHOSPHATE BINDINGPROTEIN (Pseudomonasaeruginosa) |
PF12849(PBP_like_2) | 4 | ILE A 225ILE A 230LEU A 178PHE A 179 | None | 0.74A | 3adsA-4pqjA:undetectable | 3adsA-4pqjA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ryf | ATP-DEPENDENT CLPPROTEASE PROTEOLYTICSUBUNIT (Listeriamonocytogenes) |
PF00574(CLP_protease) | 4 | ILE H 77ILE H 146LEU H 32MET H 99 | NoneNoneNoneMLI H 301 (-3.3A) | 1.09A | 3adsA-4ryfH:undetectable | 3adsA-4ryfH:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uy3 | SEPTATION RINGFORMATION REGULATOREZRA (Staphylococcusaureus) |
PF06160(EzrA) | 4 | ILE A 131ILE A 200TYR A 184LEU A 53 | None | 0.86A | 3adsA-4uy3A:undetectable | 3adsA-4uy3A:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wd9 | NISIN BIOSYNTHESISPROTEIN NISB (Lactococcuslactis) |
PF04738(Lant_dehydr_N)PF14028(Lant_dehydr_C) | 4 | ILE A 301ILE A 264LEU A 472PHE A 465 | None | 0.98A | 3adsA-4wd9A:undetectable | 3adsA-4wd9A:15.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y7p | ALKALINE D-PEPTIDASE (Bacillus cereus) |
PF00144(Beta-lactamase) | 4 | ILE A 38ILE A 217LEU A 31PHE A 35 | None | 0.99A | 3adsA-4y7pA:undetectable | 3adsA-4y7pA:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxi | TYROCIDINESYNTHETASE 3 (Acinetobacterbaumannii) |
PF00501(AMP-binding)PF00550(PP-binding)PF00668(Condensation)PF00975(Thioesterase)PF13193(AMP-binding_C) | 4 | ILE A 401ILE A 27TYR A 37LEU A 417 | NoneNonePNS A1401 (-4.7A)None | 1.14A | 3adsA-4zxiA:undetectable | 3adsA-4zxiA:12.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a9p | POLYHEDRIN (Operophterabrumatacypovirus 18) |
PF05865(Cypo_polyhedrin) | 4 | ILE A 109ILE A 225TYR A 224LEU A 68 | None | 1.09A | 3adsA-5a9pA:undetectable | 3adsA-5a9pA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5afo | FIMBRIAE (Escherichiacoli) |
PF00419(Fimbrial) | 4 | ILE A 152ILE A 169LEU A 73PHE A 82 | None | 1.17A | 3adsA-5afoA:undetectable | 3adsA-5afoA:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5djq | CBB3-TYPE CYTOCHROMEC OXIDASE SUBUNITCCON1 (Pseudomonasstutzeri) |
PF00115(COX1) | 4 | ILE A 65ILE A 168TYR A 141PHE A 68 | HEM A 502 (-4.7A)NoneNoneNone | 1.13A | 3adsA-5djqA:undetectable | 3adsA-5djqA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e24 | SUPPRESSOR OFHAIRLESS PROTEIN (Drosophilamelanogaster) |
PF09270(BTD)PF09271(LAG1-DNAbind) | 4 | ILE E 122TYR E 113LEU E 149PHE E 150 | NoneNoneEDO E 610 (-4.9A)EDO E 603 (-3.7A) | 0.88A | 3adsA-5e24E:undetectable | 3adsA-5e24E:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e3t | PHOSPHATIDYLINOSITOL-4-PHOSPHATE5-KINASE, TYPE I,ALPHA (Danio rerio) |
PF01504(PIP5K) | 4 | ILE A 133TYR A 138LEU A 150PHE A 160 | NoneNoneNoneANP A 501 (-4.1A) | 0.67A | 3adsA-5e3tA:undetectable | 3adsA-5e3tA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e6p | PLEXIN-B2 (Mus musculus) |
PF08337(Plexin_cytopl) | 4 | ILE A1432ILE A1703LEU A1636PHE A1639 | None | 1.06A | 3adsA-5e6pA:undetectable | 3adsA-5e6pA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fbh | EXTRACELLULARCALCIUM-SENSINGRECEPTOR (Homo sapiens) |
no annotation | 4 | ILE B 427ILE B 327TYR B 418LEU B 464 | None | 0.89A | 3adsA-5fbhB:undetectable | 3adsA-5fbhB:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fdk | HOLLIDAY JUNCTIONRESOLVASE RECU (Bacillussubtilis) |
PF03838(RecU) | 4 | ILE A 138ILE A 133TYR A 197LEU A 172 | None | 1.10A | 3adsA-5fdkA:undetectable | 3adsA-5fdkA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fp1 | TONB-DEPENDENTSIDEROPHORE RECEPTOR (Acinetobacterbaumannii) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | ILE A 134ILE A 268TYR A 219LEU A 61 | None | 1.08A | 3adsA-5fp1A:undetectable | 3adsA-5fp1A:16.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gpy | GENERALTRANSCRIPTION FACTORIIE SUBUNIT 1TRANSCRIPTIONINITIATION FACTORIIE SUBUNIT BETA (Homo sapiens) |
PF02002(TFIIE_alpha)PF08271(TF_Zn_Ribbon)no annotation | 4 | ILE A 28ILE A 94LEU B 190PHE B 202 | None | 1.14A | 3adsA-5gpyA:undetectable | 3adsA-5gpyA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hpk | E3 UBIQUITIN-PROTEINLIGASE NEDD4-LIKE (Homo sapiens) |
PF00632(HECT) | 4 | ILE A 675ILE A 792PHE A 711MET A 718 | None | 1.16A | 3adsA-5hpkA:undetectable | 3adsA-5hpkA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iq5 | MACRO DOMAIN (Mayaro virus) |
no annotation | 4 | ILE A 141ILE A 101LEU A 125MET A 132 | None | 0.93A | 3adsA-5iq5A:undetectable | 3adsA-5iq5A:13.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jd4 | LAE6 (unculturedbacterium) |
PF07859(Abhydrolase_3) | 4 | ILE A 285ILE A 93LEU A 295PHE A 288 | None | 1.02A | 3adsA-5jd4A:undetectable | 3adsA-5jd4A:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jwb | TYPE IINADH:UBIQUINONEOXIDOREDUCTASE (Plasmodiumfalciparum) |
PF07992(Pyr_redox_2) | 4 | ILE A 317ILE A 44TYR A 141LEU A 321 | None | 1.00A | 3adsA-5jwbA:undetectable | 3adsA-5jwbA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k5t | EXTRACELLULARCALCIUM-SENSINGRECEPTOR (Homo sapiens) |
PF01094(ANF_receptor)PF07562(NCD3G) | 4 | ILE A 427ILE A 327TYR A 418LEU A 464 | None | 0.89A | 3adsA-5k5tA:undetectable | 3adsA-5k5tA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l75 | FIG000906: PREDICTEDPERMEASE (Klebsiellapneumoniae) |
PF03739(YjgP_YjgQ) | 4 | ILE G 279ILE G 111LEU G 342PHE G 280 | None | 1.04A | 3adsA-5l75G:undetectable | 3adsA-5l75G:22.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mgv | PHENYLALANINE--TRNALIGASE,MITOCHONDRIAL (Homo sapiens) |
PF01409(tRNA-synt_2d)PF03147(FDX-ACB) | 4 | ILE A 380ILE A 293TYR A 152LEU A 401 | None | 1.12A | 3adsA-5mgvA:undetectable | 3adsA-5mgvA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n0c | TETANUS TOXIN (Clostridiumtetani) |
PF01742(Peptidase_M27)PF07951(Toxin_R_bind_C)PF07952(Toxin_trans)PF07953(Toxin_R_bind_N) | 4 | ILE A 793ILE A 934TYR A 909LEU A 745 | None | 1.14A | 3adsA-5n0cA:undetectable | 3adsA-5n0cA:12.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n1q | METHYL-COENZYME MREDUCTASE III FROMMETHANOTHERMOCOCCUSTHERMOLITHOTROPHICUSSUBUNIT BETA (Methanothermococcusthermolithotrophicus) |
PF02241(MCR_beta)PF02783(MCR_beta_N) | 4 | ILE B 42ILE B 175TYR B 170LEU B 192 | None | 1.02A | 3adsA-5n1qB:undetectable | 3adsA-5n1qB:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nkm | PROTEIN SMG-8 (Caenorhabditiselegans) |
PF10220(Smg8_Smg9) | 4 | ILE E 62ILE E 22LEU E 322MET E 315 | None | 1.12A | 3adsA-5nkmE:undetectable | 3adsA-5nkmE:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ny5 | 3,4-DIHYDROXYBENZOATE DECARBOXYLASE (Enterobactercloacae) |
PF01977(UbiD) | 4 | ILE A 190ILE A 216TYR A 217LEU A 184 | None | 1.10A | 3adsA-5ny5A:undetectable | 3adsA-5ny5A:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o3m | PROTOCATECHUATEDECARBOXYLASE (Klebsiellapneumoniae) |
PF01977(UbiD) | 4 | ILE A 190ILE A 216TYR A 217LEU A 184 | None | 1.15A | 3adsA-5o3mA:undetectable | 3adsA-5o3mA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tr0 | SEED LINOLEATE13S-LIPOXYGENASE-1 (Glycine max) |
no annotation | 4 | ILE A 434ILE A 487LEU A 362PHE A 405 | None | 1.13A | 3adsA-5tr0A:undetectable | 3adsA-5tr0A:16.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xjg | NUCLEUS-VACUOLEJUNCTION PROTEIN 1VACUOLAR PROTEIN 8 (Saccharomycescerevisiae) |
PF00514(Arm)no annotation | 4 | ILE B 295ILE A 454TYR A 451LEU B 292 | None | 1.09A | 3adsA-5xjgB:undetectable | 3adsA-5xjgB:16.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zkq | PLATELET-ACTIVATINGFACTORRECEPTOR,ENDOLYSIN,ENDOLYSIN,PLATELET-ACTIVATING FACTORRECEPTOR (Escherichiavirus T4;Homo sapiens) |
no annotation | 4 | ILE A 99ILE A 25TYR A 22PHE A 98 | NoneNone9EU A 501 (-4.7A)OLC A 502 ( 4.8A) | 0.75A | 3adsA-5zkqA:undetectable | 3adsA-5zkqA:15.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c0e | ISOCITRATEDEHYDROGENASE (Legionellapneumophila) |
no annotation | 4 | ILE A 19ILE A 52LEU A 27MET A 369 | None | 0.97A | 3adsA-6c0eA:undetectable | 3adsA-6c0eA:13.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d0n | CLC-TYPEFLUORIDE/PROTONANTIPORTER (Enterococcuscasseliflavus) |
no annotation | 4 | ILE A 364ILE A 389LEU A 376PHE A 379 | NoneDMU A 502 ( 4.7A)NoneNone | 1.13A | 3adsA-6d0nA:undetectable | 3adsA-6d0nA:17.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fos | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A1 (Cyanidioschyzonmerolae) |
no annotation | 4 | ILE A 407TYR A 408LEU A 184PHE A 187 | NoneBCR A4007 (-4.5A)NoneNone | 1.06A | 3adsA-6fosA:undetectable | 3adsA-6fosA:13.59 |