SIMILAR PATTERNS OF AMINO ACIDS FOR 3ADS_A_IMNA2_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1an7 RIBOSOMAL PROTEIN S8

(Thermus
thermophilus)
PF00410
(Ribosomal_S8)
4 ILE A  83
TYR A  20
LEU A  39
PHE A  44
None
0.90A 3adsA-1an7A:
0.0
3adsA-1an7A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1axn ANNEXIN III

(Homo sapiens)
PF00191
(Annexin)
4 ILE A  28
ILE A 314
LEU A  69
MET A  85
None
0.87A 3adsA-1axnA:
undetectable
3adsA-1axnA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c7k ZINC ENDOPROTEASE

(Streptomyces
caespitosus)
PF02031
(Peptidase_M7)
4 ILE A  65
TYR A  95
LEU A  67
PHE A  66
None
1.12A 3adsA-1c7kA:
undetectable
3adsA-1c7kA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f3l PROTEIN ARGININE
METHYLTRANSFERASE
PRMT3


(Rattus
norvegicus)
PF06325
(PrmA)
4 ILE A 416
ILE A 359
TYR A 455
LEU A 364
None
0.89A 3adsA-1f3lA:
0.0
3adsA-1f3lA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hkw DIAMINOPIMELATE
DECARBOXYLASE


(Mycobacterium
tuberculosis)
PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N)
4 ILE A  26
ILE A 261
TYR A 263
LEU A  31
None
1.13A 3adsA-1hkwA:
0.0
3adsA-1hkwA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lqw PEPTIDE DEFORMYLASE
PDF1


(Staphylococcus
aureus)
PF01327
(Pep_deformylase)
4 ILE A  66
ILE A 156
LEU A   2
PHE A  40
None
1.19A 3adsA-1lqwA:
undetectable
3adsA-1lqwA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ls4 APOLIPOPHORIN-III

(Locusta
migratoria)
no annotation 4 ILE A 118
ILE A  21
LEU A  77
PHE A  80
None
0.77A 3adsA-1ls4A:
undetectable
3adsA-1ls4A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mwo ALPHA AMYLASE

(Pyrococcus
woesei)
PF00128
(Alpha-amylase)
PF09154
(DUF1939)
4 ILE A  30
ILE A 327
LEU A  47
MET A  13
None
0.99A 3adsA-1mwoA:
0.0
3adsA-1mwoA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ogo DEXTRANASE

(Talaromyces
minioluteus)
PF03718
(Glyco_hydro_49)
PF17433
(Glyco_hydro_49N)
4 ILE X 280
ILE X 358
TYR X 381
LEU X 296
None
1.17A 3adsA-1ogoX:
0.0
3adsA-1ogoX:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION


(Saccharomyces
cerevisiae)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 ILE A 296
ILE A 185
LEU A 286
MET A 262
None
1.16A 3adsA-1q1nA:
0.0
3adsA-1q1nA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qaf PROTEIN (COPPER
AMINE OXIDASE)


(Escherichia
coli)
PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3)
PF07833
(Cu_amine_oxidN1)
4 ILE A 605
ILE A 473
LEU A 638
PHE A 580
None
0.96A 3adsA-1qafA:
undetectable
3adsA-1qafA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rif DNA HELICASE UVSW

(Escherichia
virus T4)
PF04851
(ResIII)
4 ILE A 144
ILE A 188
LEU A 133
MET A 230
None
1.00A 3adsA-1rifA:
undetectable
3adsA-1rifA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uaa PROTEIN
(ATP-DEPENDENT DNA
HELICASE REP.)


(Escherichia
coli)
PF00580
(UvrD-helicase)
PF13361
(UvrD_C)
4 ILE A  50
TYR A  45
LEU A 268
PHE A 265
None
1.17A 3adsA-1uaaA:
undetectable
3adsA-1uaaA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ga8 HYPOTHETICAL 39.9
KDA PROTEIN


(Saccharomyces
cerevisiae)
PF07728
(AAA_5)
4 ILE A 350
ILE A 342
TYR A 281
LEU A   7
None
1.14A 3adsA-2ga8A:
undetectable
3adsA-2ga8A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gko SUBTILISIN
MICROBIAL SERINE
PROTEINASES


(Bacillus
subtilis)
PF00082
(Peptidase_S8)
4 ILE A 163
ILE A  10
TYR A  14
LEU A 161
None
0.98A 3adsA-2gkoA:
undetectable
3adsA-2gkoA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmy HYPOTHETICAL PROTEIN
ATU0492


(Agrobacterium
fabrum)
PF02627
(CMD)
4 ILE A 123
ILE A  45
LEU A  30
PHE A  34
None
0.90A 3adsA-2gmyA:
undetectable
3adsA-2gmyA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hpi DNA POLYMERASE III
ALPHA SUBUNIT


(Thermus
aquaticus)
PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6)
4 ILE A 394
ILE A 410
TYR A 409
PHE A 399
None
1.16A 3adsA-2hpiA:
undetectable
3adsA-2hpiA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j0w LYSINE-SENSITIVE
ASPARTOKINASE 3


(Escherichia
coli)
PF00696
(AA_kinase)
PF01842
(ACT)
4 ILE A 180
ILE A  44
LEU A 130
MET A  20
None
1.17A 3adsA-2j0wA:
undetectable
3adsA-2j0wA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nad NAD-DEPENDENT
FORMATE
DEHYDROGENASE


(Pseudomonas sp.
101)
PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
4 ILE A 158
LEU A 210
PHE A 213
MET A 192
None
0.64A 3adsA-2nadA:
undetectable
3adsA-2nadA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nlx XYLULOSE KINASE

(Escherichia
coli)
PF00370
(FGGY_N)
PF02782
(FGGY_C)
4 ILE A 393
ILE A 385
LEU A 449
MET A 243
None
1.10A 3adsA-2nlxA:
undetectable
3adsA-2nlxA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nrj HBL B PROTEIN

(Bacillus cereus)
PF05791
(Bacillus_HBL)
4 ILE A 259
ILE A 270
LEU A  43
MET A  36
None
0.95A 3adsA-2nrjA:
undetectable
3adsA-2nrjA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oca ATP-DEPENDENT DNA
HELICASE UVSW


(Escherichia
virus T4)
PF00271
(Helicase_C)
PF04851
(ResIII)
4 ILE A 144
ILE A 188
LEU A 133
MET A 230
None
0.98A 3adsA-2ocaA:
undetectable
3adsA-2ocaA:
21.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2p54 PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA


(Homo sapiens)
PF00104
(Hormone_recep)
5 ILE A 272
ILE A 317
LEU A 347
PHE A 351
MET A 355
735  A 469 ( 4.2A)
735  A 469 ( 4.8A)
None
None
735  A 469 (-2.9A)
0.38A 3adsA-2p54A:
37.1
3adsA-2p54A:
61.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q0t PUTATIVE
GAMMA-CARBOXYMUCONOL
ACTONE DECARBOXYLASE
SUBUNIT


(Paraburkholderia
xenovorans)
PF02627
(CMD)
4 ILE A  63
ILE A 236
TYR A  42
LEU A  55
None
0.92A 3adsA-2q0tA:
undetectable
3adsA-2q0tA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q88 PUTATIVE ABC
TRANSPORTER AMINO
ACID-BINDING PROTEIN


(Sinorhizobium
meliloti)
PF00497
(SBP_bac_3)
4 ILE A 233
ILE A  18
LEU A 224
PHE A 230
None
1.15A 3adsA-2q88A:
undetectable
3adsA-2q88A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qp2 UNKNOWN PROTEIN

(Photorhabdus
laumondii)
PF01823
(MACPF)
4 ILE A 325
LEU A  64
PHE A 202
MET A  61
None
1.13A 3adsA-2qp2A:
undetectable
3adsA-2qp2A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qsr TRANSCRIPTION-REPAIR
COUPLING FACTOR


(Streptococcus
pneumoniae)
PF03461
(TRCF)
4 ILE A1073
ILE A1027
TYR A1026
LEU A1147
None
0.74A 3adsA-2qsrA:
undetectable
3adsA-2qsrA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qv2 INOSITOL
POLYPHOSPHATE
5-PHOSPHATASE OCRL-1


(Homo sapiens)
PF00620
(RhoGAP)
4 ILE A 301
ILE A 244
LEU A 288
MET A 281
ILE  A 301 ( 0.7A)
ILE  A 244 ( 0.7A)
LEU  A 288 ( 0.6A)
MET  A 281 ( 0.0A)
1.01A 3adsA-2qv2A:
undetectable
3adsA-2qv2A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qwu INTRACELLULAR GROWTH
LOCUS, SUBUNIT C


(Francisella
tularensis)
PF11550
(IglC)
4 ILE A  89
ILE A   7
LEU A  91
MET A  36
None
1.05A 3adsA-2qwuA:
undetectable
3adsA-2qwuA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uwb CELLULASE

(Tropaeolum
majus)
PF00722
(Glyco_hydro_16)
PF06955
(XET_C)
4 ILE A  95
ILE A  66
TYR A 205
LEU A 173
None
1.03A 3adsA-2uwbA:
undetectable
3adsA-2uwbA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpn PERIPLASMIC
SUBSTRATE BINDING
PROTEIN


(Halomonas
elongata)
PF03480
(DctP)
4 ILE A  79
ILE A 274
LEU A 300
PHE A 303
None
1.06A 3adsA-2vpnA:
undetectable
3adsA-2vpnA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vxk GLUCOSAMINE
6-PHOSPHATE
ACETYLTRANSFERASE


(Aspergillus
fumigatus)
PF00583
(Acetyltransf_1)
4 ILE A 147
ILE A 106
TYR A  62
LEU A 164
None
None
None
16G  A1191 ( 3.9A)
1.04A 3adsA-2vxkA:
undetectable
3adsA-2vxkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w5s PROCESSED GLYCEROL
PHOSPHATE
LIPOTEICHOIC ACID
SYNTHASE


(Staphylococcus
aureus)
PF00884
(Sulfatase)
4 ILE A 252
ILE A 365
TYR A 360
LEU A 254
None
1.17A 3adsA-2w5sA:
undetectable
3adsA-2w5sA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yg6 PUTRESCINE OXIDASE

(Rhodococcus
erythropolis)
PF01593
(Amino_oxidase)
4 ILE A 169
LEU A 199
PHE A 168
MET A 122
None
0.91A 3adsA-2yg6A:
undetectable
3adsA-2yg6A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yij PHOSPHOLIPASE
A1-IIGAMMA


(Arabidopsis
thaliana)
PF01764
(Lipase_3)
4 ILE A 193
ILE A 232
LEU A 114
PHE A 113
None
1.09A 3adsA-2yijA:
undetectable
3adsA-2yijA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yxb COENZYME
B12-DEPENDENT MUTASE


(Aeropyrum
pernix)
PF02310
(B12-binding)
4 ILE A  75
ILE A 111
LEU A  95
MET A  88
None
0.85A 3adsA-2yxbA:
undetectable
3adsA-2yxbA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yzw ADP-RIBOSYLGLYCOHYDR
OLASE


(Thermus
thermophilus)
PF03747
(ADP_ribosyl_GH)
4 ILE A 272
LEU A  50
PHE A  54
MET A  42
None
0.99A 3adsA-2yzwA:
undetectable
3adsA-2yzwA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a64 CELLOBIOHYDROLASE

(Coprinopsis
cinerea)
PF01341
(Glyco_hydro_6)
4 ILE A 191
ILE A 129
TYR A 125
LEU A 152
None
0.90A 3adsA-3a64A:
undetectable
3adsA-3a64A:
18.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA


(Homo sapiens)
PF00104
(Hormone_recep)
6 ILE A 281
ILE A 326
TYR A 327
LEU A 356
PHE A 360
MET A 364
MC5  A   1 ( 4.8A)
MC5  A   1 ( 4.9A)
None
None
None
MC5  A   1 (-3.7A)
0.37A 3adsA-3b0qA:
42.0
3adsA-3b0qA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE


(unidentified)
PF01979
(Amidohydro_1)
4 ILE A 355
ILE A  16
LEU A 130
MET A  59
None
0.93A 3adsA-3be7A:
undetectable
3adsA-3be7A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d1l PUTATIVE NADP
OXIDOREDUCTASE
BF3122


(Bacteroides
fragilis)
PF03807
(F420_oxidored)
PF10728
(DUF2520)
4 ILE A  13
ILE A 152
LEU A  73
PHE A  78
None
1.08A 3adsA-3d1lA:
undetectable
3adsA-3d1lA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dls PAS
DOMAIN-CONTAINING
SERINE/THREONINE-PRO
TEIN KINASE


(Homo sapiens)
PF00069
(Pkinase)
4 ILE A1108
ILE A1065
LEU A1196
PHE A1109
None
ADP  A   1 (-4.0A)
None
None
1.14A 3adsA-3dlsA:
undetectable
3adsA-3dlsA:
20.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA


(Homo sapiens)
PF00104
(Hormone_recep)
PF00105
(zf-C4)
5 ILE D 281
ILE D 326
LEU D 356
PHE D 360
MET D 364
PLB  D 701 (-4.6A)
PLB  D 701 ( 4.5A)
None
None
PLB  D 701 ( 4.8A)
0.54A 3adsA-3dzuD:
37.2
3adsA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA


(Homo sapiens)
PF00104
(Hormone_recep)
PF00105
(zf-C4)
5 ILE D 326
TYR D 327
LEU D 356
PHE D 360
MET D 364
PLB  D 701 ( 4.5A)
None
None
None
PLB  D 701 ( 4.8A)
0.62A 3adsA-3dzuD:
37.2
3adsA-3dzuD:
94.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ian CHITINASE

(Lactococcus
lactis)
PF00704
(Glyco_hydro_18)
4 ILE A 281
ILE A 214
TYR A 210
LEU A 283
None
0.72A 3adsA-3ianA:
undetectable
3adsA-3ianA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ilr HEPARIN LYASE I

(Bacteroides
thetaiotaomicron)
PF14099
(Polysacc_lyase)
4 ILE A 240
ILE A 135
TYR A 368
LEU A 229
None
1.12A 3adsA-3ilrA:
undetectable
3adsA-3ilrA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE


(Escherichia
coli)
PF03710
(GlnE)
PF08335
(GlnD_UR_UTase)
4 ILE A 484
ILE A 496
LEU A 455
MET A 508
None
1.16A 3adsA-3k7dA:
undetectable
3adsA-3k7dA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3omn CYTOCHROME C
OXIDASE, AA3 TYPE,
SUBUNIT I


(Rhodobacter
sphaeroides)
PF00115
(COX1)
4 ILE A 232
ILE A 310
PHE A 233
MET A 320
None
1.16A 3adsA-3omnA:
undetectable
3adsA-3omnA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ozy PUTATIVE MANDELATE
RACEMASE


(Bordetella
bronchiseptica)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 ILE A 284
ILE A 309
TYR A 344
LEU A 130
None
1.11A 3adsA-3ozyA:
undetectable
3adsA-3ozyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qw3 OROTIDINE-5-PHOSPHAT
E
DECARBOXYLASE/OROTAT
E
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE
(OMPDCASE-OPRTASE,
PUTATIVE)


(Leishmania
infantum)
PF00215
(OMPdecase)
4 ILE A 248
ILE A  77
TYR A  48
LEU A 208
None
1.05A 3adsA-3qw3A:
undetectable
3adsA-3qw3A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qw4 UMP SYNTHASE

(Leishmania
donovani)
PF00156
(Pribosyltran)
PF00215
(OMPdecase)
4 ILE B 248
ILE B  77
TYR B  48
LEU B 208
None
1.03A 3adsA-3qw4B:
undetectable
3adsA-3qw4B:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rkx BIOTIN-[ACETYL-COA-C
ARBOXYLASE] LIGASE


(Staphylococcus
aureus)
PF03099
(BPL_LplA_LipB)
PF08279
(HTH_11)
4 ILE A  71
ILE A 111
TYR A  88
LEU A   9
None
1.10A 3adsA-3rkxA:
undetectable
3adsA-3rkxA:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN


(Enterococcus
faecalis)
PF09711
(Cas_Csn2)
4 ILE A  35
ILE A  65
TYR A 172
LEU A  31
None
1.16A 3adsA-3s5uA:
undetectable
3adsA-3s5uA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tlm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 1


(Bos taurus)
PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF08282
(Hydrolase_3)
PF13246
(Cation_ATPase)
4 ILE A 742
ILE A 752
LEU A 734
MET A 326
None
1.17A 3adsA-3tlmA:
undetectable
3adsA-3tlmA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE


(Gluconobacter
oxydans)
PF00171
(Aldedh)
4 ILE A 201
LEU A  20
PHE A 186
MET A  26
None
1.14A 3adsA-3vz0A:
undetectable
3adsA-3vz0A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wwp (S)-HYDROXYNITRILE
LYASE


(Baliospermum
montanum)
PF00561
(Abhydrolase_1)
4 ILE A  84
ILE A  65
TYR A  93
LEU A 183
None
1.07A 3adsA-3wwpA:
undetectable
3adsA-3wwpA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bfr PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC S
SUBUNIT BETA ISOFORM


(Mus musculus)
PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
PF00792
(PI3K_C2)
PF00794
(PI3K_rbd)
4 ILE A 919
ILE A 935
LEU A 927
PHE A 928
None
0.78A 3adsA-4bfrA:
undetectable
3adsA-4bfrA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bxw FACTOR XA

(Pseudonaja
textilis)
PF00089
(Trypsin)
PF14670
(FXa_inhibition)
4 ILE A 275
ILE A 408
TYR A 243
LEU A 237
None
1.15A 3adsA-4bxwA:
undetectable
3adsA-4bxwA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cdb LISTERIOLYSIN O

(Listeria
monocytogenes)
PF01289
(Thiol_cytolysin)
PF17440
(Thiol_cytolys_C)
4 ILE A 249
ILE A 108
TYR A 406
LEU A 306
None
NA  A1536 ( 4.4A)
NA  A1536 (-4.5A)
None
1.10A 3adsA-4cdbA:
undetectable
3adsA-4cdbA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fbq DNA REPAIR AND
TELOMERE MAINTENANCE
PROTEIN NBS1,DNA
REPAIR PROTEIN RAD32
CHIMERIC PROTEIN


(Schizosaccharomyces
pombe)
PF00149
(Metallophos)
PF04152
(Mre11_DNA_bind)
4 ILE A1114
TYR A1116
LEU A1292
MET A1059
None
1.16A 3adsA-4fbqA:
undetectable
3adsA-4fbqA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jdy PYRIDOXAL
BIOSYNTHESIS LYASE
PDXS


(Mycobacterium
tuberculosis)
PF01680
(SOR_SNZ)
4 ILE A 151
ILE A 220
LEU A 210
MET A 169
None
1.13A 3adsA-4jdyA:
undetectable
3adsA-4jdyA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lej VICILIN

(Pinus
koraiensis)
PF00190
(Cupin_1)
4 ILE A 177
TYR A 195
LEU A 175
MET A 117
None
None
None
GOL  A 503 ( 4.9A)
0.73A 3adsA-4lejA:
undetectable
3adsA-4lejA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mb2 PHOSPHOPANTOTHENATE
SYNTHETASE


(Thermococcus
onnurineus)
PF02006
(PPS_PS)
4 ILE A  47
ILE A 254
LEU A 182
PHE A  43
None
None
ATP  A 301 (-3.8A)
None
0.96A 3adsA-4mb2A:
undetectable
3adsA-4mb2A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nu7 RIBULOSE-PHOSPHATE
3-EPIMERASE


(Toxoplasma
gondii)
PF00834
(Ribul_P_3_epim)
4 ILE A  92
ILE A   8
LEU A  72
PHE A  94
None
0.83A 3adsA-4nu7A:
undetectable
3adsA-4nu7A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o4f INOSITOL
HEXAKISPHOSPHATE
KINASE


(Entamoeba
histolytica)
PF03770
(IPK)
4 ILE A 169
ILE A 142
LEU A 100
MET A 138
None
1.06A 3adsA-4o4fA:
undetectable
3adsA-4o4fA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p0v FARNESYL
PYROPHOSPHATE
SYNTHASE


(Homo sapiens)
PF00348
(polyprenyl_synt)
4 ILE A 210
ILE A 139
LEU A 232
PHE A 206
None
1.18A 3adsA-4p0vA:
undetectable
3adsA-4p0vA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pqj PHOSPHATE BINDING
PROTEIN


(Pseudomonas
aeruginosa)
PF12849
(PBP_like_2)
4 ILE A 225
ILE A 230
LEU A 178
PHE A 179
None
0.74A 3adsA-4pqjA:
undetectable
3adsA-4pqjA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ryf ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT


(Listeria
monocytogenes)
PF00574
(CLP_protease)
4 ILE H  77
ILE H 146
LEU H  32
MET H  99
None
None
None
MLI  H 301 (-3.3A)
1.09A 3adsA-4ryfH:
undetectable
3adsA-4ryfH:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uy3 SEPTATION RING
FORMATION REGULATOR
EZRA


(Staphylococcus
aureus)
PF06160
(EzrA)
4 ILE A 131
ILE A 200
TYR A 184
LEU A  53
None
0.86A 3adsA-4uy3A:
undetectable
3adsA-4uy3A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd9 NISIN BIOSYNTHESIS
PROTEIN NISB


(Lactococcus
lactis)
PF04738
(Lant_dehydr_N)
PF14028
(Lant_dehydr_C)
4 ILE A 301
ILE A 264
LEU A 472
PHE A 465
None
0.98A 3adsA-4wd9A:
undetectable
3adsA-4wd9A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y7p ALKALINE D-PEPTIDASE

(Bacillus cereus)
PF00144
(Beta-lactamase)
4 ILE A  38
ILE A 217
LEU A  31
PHE A  35
None
0.99A 3adsA-4y7pA:
undetectable
3adsA-4y7pA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxi TYROCIDINE
SYNTHETASE 3


(Acinetobacter
baumannii)
PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00668
(Condensation)
PF00975
(Thioesterase)
PF13193
(AMP-binding_C)
4 ILE A 401
ILE A  27
TYR A  37
LEU A 417
None
None
PNS  A1401 (-4.7A)
None
1.14A 3adsA-4zxiA:
undetectable
3adsA-4zxiA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a9p POLYHEDRIN

(Operophtera
brumata
cypovirus 18)
PF05865
(Cypo_polyhedrin)
4 ILE A 109
ILE A 225
TYR A 224
LEU A  68
None
1.09A 3adsA-5a9pA:
undetectable
3adsA-5a9pA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5afo FIMBRIAE

(Escherichia
coli)
PF00419
(Fimbrial)
4 ILE A 152
ILE A 169
LEU A  73
PHE A  82
None
1.17A 3adsA-5afoA:
undetectable
3adsA-5afoA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5djq CBB3-TYPE CYTOCHROME
C OXIDASE SUBUNIT
CCON1


(Pseudomonas
stutzeri)
PF00115
(COX1)
4 ILE A  65
ILE A 168
TYR A 141
PHE A  68
HEM  A 502 (-4.7A)
None
None
None
1.13A 3adsA-5djqA:
undetectable
3adsA-5djqA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e24 SUPPRESSOR OF
HAIRLESS PROTEIN


(Drosophila
melanogaster)
PF09270
(BTD)
PF09271
(LAG1-DNAbind)
4 ILE E 122
TYR E 113
LEU E 149
PHE E 150
None
None
EDO  E 610 (-4.9A)
EDO  E 603 (-3.7A)
0.88A 3adsA-5e24E:
undetectable
3adsA-5e24E:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e3t PHOSPHATIDYLINOSITOL
-4-PHOSPHATE
5-KINASE, TYPE I,
ALPHA


(Danio rerio)
PF01504
(PIP5K)
4 ILE A 133
TYR A 138
LEU A 150
PHE A 160
None
None
None
ANP  A 501 (-4.1A)
0.67A 3adsA-5e3tA:
undetectable
3adsA-5e3tA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e6p PLEXIN-B2

(Mus musculus)
PF08337
(Plexin_cytopl)
4 ILE A1432
ILE A1703
LEU A1636
PHE A1639
None
1.06A 3adsA-5e6pA:
undetectable
3adsA-5e6pA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR


(Homo sapiens)
no annotation 4 ILE B 427
ILE B 327
TYR B 418
LEU B 464
None
0.89A 3adsA-5fbhB:
undetectable
3adsA-5fbhB:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fdk HOLLIDAY JUNCTION
RESOLVASE RECU


(Bacillus
subtilis)
PF03838
(RecU)
4 ILE A 138
ILE A 133
TYR A 197
LEU A 172
None
1.10A 3adsA-5fdkA:
undetectable
3adsA-5fdkA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fp1 TONB-DEPENDENT
SIDEROPHORE RECEPTOR


(Acinetobacter
baumannii)
PF00593
(TonB_dep_Rec)
PF07715
(Plug)
4 ILE A 134
ILE A 268
TYR A 219
LEU A  61
None
1.08A 3adsA-5fp1A:
undetectable
3adsA-5fp1A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gpy GENERAL
TRANSCRIPTION FACTOR
IIE SUBUNIT 1
TRANSCRIPTION
INITIATION FACTOR
IIE SUBUNIT BETA


(Homo sapiens)
PF02002
(TFIIE_alpha)
PF08271
(TF_Zn_Ribbon)
no annotation
4 ILE A  28
ILE A  94
LEU B 190
PHE B 202
None
1.14A 3adsA-5gpyA:
undetectable
3adsA-5gpyA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hpk E3 UBIQUITIN-PROTEIN
LIGASE NEDD4-LIKE


(Homo sapiens)
PF00632
(HECT)
4 ILE A 675
ILE A 792
PHE A 711
MET A 718
None
1.16A 3adsA-5hpkA:
undetectable
3adsA-5hpkA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iq5 MACRO DOMAIN

(Mayaro virus)
no annotation 4 ILE A 141
ILE A 101
LEU A 125
MET A 132
None
0.93A 3adsA-5iq5A:
undetectable
3adsA-5iq5A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jd4 LAE6

(uncultured
bacterium)
PF07859
(Abhydrolase_3)
4 ILE A 285
ILE A  93
LEU A 295
PHE A 288
None
1.02A 3adsA-5jd4A:
undetectable
3adsA-5jd4A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jwb TYPE II
NADH:UBIQUINONE
OXIDOREDUCTASE


(Plasmodium
falciparum)
PF07992
(Pyr_redox_2)
4 ILE A 317
ILE A  44
TYR A 141
LEU A 321
None
1.00A 3adsA-5jwbA:
undetectable
3adsA-5jwbA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k5t EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR


(Homo sapiens)
PF01094
(ANF_receptor)
PF07562
(NCD3G)
4 ILE A 427
ILE A 327
TYR A 418
LEU A 464
None
0.89A 3adsA-5k5tA:
undetectable
3adsA-5k5tA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l75 FIG000906: PREDICTED
PERMEASE


(Klebsiella
pneumoniae)
PF03739
(YjgP_YjgQ)
4 ILE G 279
ILE G 111
LEU G 342
PHE G 280
None
1.04A 3adsA-5l75G:
undetectable
3adsA-5l75G:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mgv PHENYLALANINE--TRNA
LIGASE,
MITOCHONDRIAL


(Homo sapiens)
PF01409
(tRNA-synt_2d)
PF03147
(FDX-ACB)
4 ILE A 380
ILE A 293
TYR A 152
LEU A 401
None
1.12A 3adsA-5mgvA:
undetectable
3adsA-5mgvA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n0c TETANUS TOXIN

(Clostridium
tetani)
PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N)
4 ILE A 793
ILE A 934
TYR A 909
LEU A 745
None
1.14A 3adsA-5n0cA:
undetectable
3adsA-5n0cA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n1q METHYL-COENZYME M
REDUCTASE III FROM
METHANOTHERMOCOCCUS
THERMOLITHOTROPHICUS
SUBUNIT BETA


(Methanothermococcus
thermolithotrophicus)
PF02241
(MCR_beta)
PF02783
(MCR_beta_N)
4 ILE B  42
ILE B 175
TYR B 170
LEU B 192
None
1.02A 3adsA-5n1qB:
undetectable
3adsA-5n1qB:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nkm PROTEIN SMG-8

(Caenorhabditis
elegans)
PF10220
(Smg8_Smg9)
4 ILE E  62
ILE E  22
LEU E 322
MET E 315
None
1.12A 3adsA-5nkmE:
undetectable
3adsA-5nkmE:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ny5 3,4-DIHYDROXYBENZOAT
E DECARBOXYLASE


(Enterobacter
cloacae)
PF01977
(UbiD)
4 ILE A 190
ILE A 216
TYR A 217
LEU A 184
None
1.10A 3adsA-5ny5A:
undetectable
3adsA-5ny5A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o3m PROTOCATECHUATE
DECARBOXYLASE


(Klebsiella
pneumoniae)
PF01977
(UbiD)
4 ILE A 190
ILE A 216
TYR A 217
LEU A 184
None
1.15A 3adsA-5o3mA:
undetectable
3adsA-5o3mA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1


(Glycine max)
no annotation 4 ILE A 434
ILE A 487
LEU A 362
PHE A 405
None
1.13A 3adsA-5tr0A:
undetectable
3adsA-5tr0A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjg NUCLEUS-VACUOLE
JUNCTION PROTEIN 1
VACUOLAR PROTEIN 8


(Saccharomyces
cerevisiae)
PF00514
(Arm)
no annotation
4 ILE B 295
ILE A 454
TYR A 451
LEU B 292
None
1.09A 3adsA-5xjgB:
undetectable
3adsA-5xjgB:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zkq PLATELET-ACTIVATING
FACTOR
RECEPTOR,ENDOLYSIN,E
NDOLYSIN,PLATELET-AC
TIVATING FACTOR
RECEPTOR


(Escherichia
virus T4;
Homo sapiens)
no annotation 4 ILE A  99
ILE A  25
TYR A  22
PHE A  98
None
None
9EU  A 501 (-4.7A)
OLC  A 502 ( 4.8A)
0.75A 3adsA-5zkqA:
undetectable
3adsA-5zkqA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c0e ISOCITRATE
DEHYDROGENASE


(Legionella
pneumophila)
no annotation 4 ILE A  19
ILE A  52
LEU A  27
MET A 369
None
0.97A 3adsA-6c0eA:
undetectable
3adsA-6c0eA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d0n CLC-TYPE
FLUORIDE/PROTON
ANTIPORTER


(Enterococcus
casseliflavus)
no annotation 4 ILE A 364
ILE A 389
LEU A 376
PHE A 379
None
DMU  A 502 ( 4.7A)
None
None
1.13A 3adsA-6d0nA:
undetectable
3adsA-6d0nA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1


(Cyanidioschyzon
merolae)
no annotation 4 ILE A 407
TYR A 408
LEU A 184
PHE A 187
None
BCR  A4007 (-4.5A)
None
None
1.06A 3adsA-6fosA:
undetectable
3adsA-6fosA:
13.59