SIMILAR PATTERNS OF AMINO ACIDS FOR 3ABK_J_CHDJ60_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d02 | TYPE II RESTRICTIONENZYME MUNI (Mycoplasma) |
PF11407(RestrictionMunI) | 4 | ILE A 86LEU A 42PHE A 35LEU A 189 | None | 0.94A | 3abkA-1d02A:undetectable3abkJ-1d02A:0.0 | 3abkA-1d02A:17.473abkJ-1d02A:14.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d1j | PROFILIN II (Homo sapiens) |
PF00235(Profilin) | 4 | PHE A 58ARG A 74MET A 85THR A 84 | None | 0.84A | 3abkA-1d1jA:undetectable3abkJ-1d1jA:undetectable | 3abkA-1d1jA:15.873abkJ-1d1jA:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1flo | FLP RECOMBINASE (Saccharomycescerevisiae) |
PF03930(Flp_N)PF05202(Flp_C) | 5 | ILE A 350ARG A 308MET A 311THR A 312LEU A 315 | None | 1.16A | 3abkA-1floA:0.03abkJ-1floA:0.0 | 3abkA-1floA:21.783abkJ-1floA:9.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1har | HIV-1 REVERSETRANSCRIPTASE(FINGERS AND PALMSUBDOMAINS) (Humanimmunodeficiencyvirus 1) |
PF00078(RVT_1) | 4 | LEU A 109MET A 164THR A 165LEU A 168 | None | 0.72A | 3abkA-1harA:undetectable3abkJ-1harA:0.1 | 3abkA-1harA:18.003abkJ-1harA:13.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iv8 | MALTOOLIGOSYLTREHALOSE SYNTHASE (Sulfolobusacidocaldarius) |
PF00128(Alpha-amylase)PF09196(DUF1953) | 4 | ILE A 129LEU A 181TYR A 190LEU A 104 | NoneNoneNoneMLZ A 105 ( 4.3A) | 0.92A | 3abkA-1iv8A:0.03abkJ-1iv8A:0.0 | 3abkA-1iv8A:20.683abkJ-1iv8A:5.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jed | SULFATEADENYLYLTRANSFERASE (Saccharomycescerevisiae) |
PF01747(ATP-sulfurylase)PF14306(PUA_2) | 5 | ILE A 48LEU A 49ARG A 40THR A 38LEU A 37 | None | 0.97A | 3abkA-1jedA:0.03abkJ-1jedA:0.0 | 3abkA-1jedA:21.173abkJ-1jedA:8.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kt8 | BRANCHED-CHAIN AMINOACIDAMINOTRANSFERASE,MITOCHONDRIAL (Homo sapiens) |
PF01063(Aminotran_4) | 4 | ILE A 332MET A 293THR A 292LEU A 235 | None | 0.81A | 3abkA-1kt8A:0.03abkJ-1kt8A:0.0 | 3abkA-1kt8A:22.713abkJ-1kt8A:12.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l2m | REP PROTEIN (Tomato yellowleaf curlSardinia virus) |
PF00799(Gemini_AL1) | 4 | ILE A 9PHE A 7THR A 17LEU A 16 | None | 0.88A | 3abkA-1l2mA:undetectable3abkJ-1l2mA:undetectable | 3abkA-1l2mA:10.723abkJ-1l2mA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mc8 | FLAP ENDONUCLEASE-1 (Pyrococcushorikoshii) |
PF00752(XPG_N)PF00867(XPG_I) | 4 | ILE A 5LEU A 8ARG A 223THR A 222 | None | 0.93A | 3abkA-1mc8A:undetectable3abkJ-1mc8A:0.0 | 3abkA-1mc8A:20.593abkJ-1mc8A:10.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mhz | METHANEMONOOXYGENASEHYDROXYLASE (Methylosinustrichosporium) |
PF02332(Phenol_Hydrox) | 5 | ILE D 318LEU D 321ARG D 330THR D 269LEU D 267 | None | 1.49A | 3abkA-1mhzD:1.73abkJ-1mhzD:undetectable | 3abkA-1mhzD:21.423abkJ-1mhzD:6.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mw5 | HYPOTHETICAL PROTEINHI1480 (Haemophilusinfluenzae) |
no annotation | 5 | ILE A 135LEU A 62PHE A 131THR A 32LEU A 34 | None | 1.27A | 3abkA-1mw5A:0.03abkJ-1mw5A:undetectable | 3abkA-1mw5A:15.693abkJ-1mw5A:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1no8 | ALY (Mus musculus) |
PF00076(RRM_1) | 5 | ILE A 121LEU A 124PHE A 125MET A 175LEU A 170 | None | 1.20A | 3abkA-1no8A:undetectable3abkJ-1no8A:undetectable | 3abkA-1no8A:11.243abkJ-1no8A:28.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1odo | PUTATIVE CYTOCHROMEP450 154A1 (Streptomycescoelicolor) |
PF00067(p450) | 4 | PHE A 106MET A 210THR A 211LEU A 214 | HEM A1407 (-4.5A)NoneNoneNone | 0.93A | 3abkA-1odoA:0.23abkJ-1odoA:undetectable | 3abkA-1odoA:23.133abkJ-1odoA:9.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pm2 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1BETA CHAIN (Escherichiacoli) |
PF00268(Ribonuc_red_sm) | 5 | ILE A 335LEU A 339TYR A 310ARG A 328THR A 312 | NoneNoneNone HG A 614 ( 4.9A)None | 1.20A | 3abkA-1pm2A:1.63abkJ-1pm2A:undetectable | 3abkA-1pm2A:19.193abkJ-1pm2A:11.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r6x | ATP:SULFATEADENYLYLTRANSFERASE (Saccharomycescerevisiae) |
PF01747(ATP-sulfurylase)PF14306(PUA_2) | 5 | ILE A 48LEU A 49ARG A 40THR A 38LEU A 37 | None | 0.98A | 3abkA-1r6xA:undetectable3abkJ-1r6xA:undetectable | 3abkA-1r6xA:21.483abkJ-1r6xA:11.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ska | 3-PHYTASE A (Aspergillusfumigatus) |
PF00328(His_Phos_2) | 4 | LEU A 261PHE A 262THR A 230LEU A 229 | None | 0.87A | 3abkA-1skaA:undetectable3abkJ-1skaA:undetectable | 3abkA-1skaA:19.893abkJ-1skaA:11.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uv7 | GENERAL SECRETIONPATHWAY PROTEIN M (Vibrio cholerae) |
PF04612(T2SSM) | 4 | ILE A 143LEU A 159ARG A 147LEU A 120 | None | 0.94A | 3abkA-1uv7A:undetectable3abkJ-1uv7A:undetectable | 3abkA-1uv7A:11.073abkJ-1uv7A:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vqt | OROTIDINE5'-PHOSPHATEDECARBOXYLASE (Thermotogamaritima) |
PF00215(OMPdecase) | 4 | ILE A 143ARG A 118MET A 116LEU A 112 | None | 0.85A | 3abkA-1vqtA:undetectable3abkJ-1vqtA:undetectable | 3abkA-1vqtA:17.183abkJ-1vqtA:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w1k | VANILLYL-ALCOHOLOXIDASE (Penicilliumsimplicissimum) |
PF01565(FAD_binding_4)PF02913(FAD-oxidase_C) | 4 | ILE A 250LEU A 253ARG A 211LEU A 204 | None | 0.86A | 3abkA-1w1kA:undetectable3abkJ-1w1kA:undetectable | 3abkA-1w1kA:22.153abkJ-1w1kA:6.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wn0 | HISTIDINE-CONTAININGPHOSPHOTRANSFERPROTEIN (Zea mays) |
PF01627(Hpt) | 5 | LEU A 30PHE A 27MET A 134THR A 133LEU A 135 | None | 1.38A | 3abkA-1wn0A:2.83abkJ-1wn0A:undetectable | 3abkA-1wn0A:13.043abkJ-1wn0A:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xl8 | PEROXISOMALCARNITINEO-OCTANOYLTRANSFERASE (Mus musculus) |
PF00755(Carn_acyltransf) | 4 | ILE A 192LEU A 273PHE A 274LEU A 211 | None | 0.79A | 3abkA-1xl8A:2.33abkJ-1xl8A:undetectable | 3abkA-1xl8A:19.903abkJ-1xl8A:6.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y8q | UBIQUITIN-LIKE 2ACTIVATING ENZYMEE1B (Homo sapiens) |
PF00899(ThiF)PF14732(UAE_UbL)PF16195(UBA2_C) | 4 | ILE B 365PHE B 366THR B 268LEU B 267 | None | 0.92A | 3abkA-1y8qB:2.93abkJ-1y8qB:undetectable | 3abkA-1y8qB:21.773abkJ-1y8qB:7.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ycg | NITRIC OXIDEREDUCTASE (Moorellathermoacetica) |
PF00258(Flavodoxin_1)PF00753(Lactamase_B) | 4 | ILE A 367LEU A 340ARG A 305LEU A 277 | None | 0.91A | 3abkA-1ycgA:undetectable3abkJ-1ycgA:undetectable | 3abkA-1ycgA:22.053abkJ-1ycgA:7.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ys7 | TRANSCRIPTIONALREGULATORY PROTEINPRRA (Mycobacteriumtuberculosis) |
PF00072(Response_reg)PF00486(Trans_reg_C) | 4 | LEU A 160PHE A 165THR A 138LEU A 142 | None | 0.91A | 3abkA-1ys7A:undetectable3abkJ-1ys7A:undetectable | 3abkA-1ys7A:18.223abkJ-1ys7A:14.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zv4 | REGULATOR OFG-PROTEIN SIGNALING17 (Homo sapiens) |
PF00615(RGS) | 4 | ILE X 178LEU X 181ARG X 95LEU X 102 | None | 0.92A | 3abkA-1zv4X:undetectable3abkJ-1zv4X:undetectable | 3abkA-1zv4X:13.673abkJ-1zv4X:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b9b | FUSION GLYCOPROTEINF0 (Mammalianrubulavirus 5) |
PF00523(Fusion_gly) | 4 | LEU A 227TYR A 72THR A 77LEU A 80 | None | 0.71A | 3abkA-2b9bA:undetectable3abkJ-2b9bA:2.3 | 3abkA-2b9bA:21.633abkJ-2b9bA:9.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cfo | GLUTAMYL-TRNASYNTHETASE (Synechococcuselongatus) |
PF00749(tRNA-synt_1c) | 4 | LEU A 39PHE A 37ARG A 21LEU A 15 | None | 0.90A | 3abkA-2cfoA:undetectable3abkJ-2cfoA:undetectable | 3abkA-2cfoA:21.243abkJ-2cfoA:9.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cph | RNA BINDING MOTIFPROTEIN 19 (Mus musculus) |
PF00076(RRM_1) | 4 | ILE A 478LEU A 481PHE A 482ARG A 467 | None | 0.91A | 3abkA-2cphA:undetectable3abkJ-2cphA:undetectable | 3abkA-2cphA:12.763abkJ-2cphA:24.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dx5 | VACUOLAR PROTEINSORTING PROTEIN 36 (Mus musculus) |
PF11605(Vps36_ESCRT-II) | 5 | ILE A 82LEU A 108PHE A 110ARG A 120LEU A 42 | None | 1.25A | 3abkA-2dx5A:undetectable3abkJ-2dx5A:undetectable | 3abkA-2dx5A:12.453abkJ-2dx5A:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g9b | CALBINDIN (Rattusnorvegicus) |
PF13405(EF-hand_6)PF13499(EF-hand_7) | 5 | ILE A 118PHE A 126MET A 167THR A 165LEU A 164 | None | 1.46A | 3abkA-2g9bA:undetectable3abkJ-2g9bA:undetectable | 3abkA-2g9bA:16.243abkJ-2g9bA:11.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h6o | MAJOR OUTER ENVELOPEGLYCOPROTEIN GP350 (Humangammaherpesvirus4) |
PF05109(Herpes_BLLF1) | 4 | PHE A 52ARG A 107THR A 105LEU A 104 | None | 0.89A | 3abkA-2h6oA:undetectable3abkJ-2h6oA:undetectable | 3abkA-2h6oA:23.023abkJ-2h6oA:8.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hnz | REVERSETRANSCRIPTASE/RIBONUCLEASE H (Humanimmunodeficiencyvirus 1) |
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb) | 4 | LEU A 109MET A 164THR A 165LEU A 168 | None | 0.78A | 3abkA-2hnzA:2.13abkJ-2hnzA:undetectable | 3abkA-2hnzA:19.773abkJ-2hnzA:6.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2idc | ANTI-SILENCINGPROTEIN 1 ANDHISTONE H3 CHIMERA (Saccharomycescerevisiae) |
PF04729(ASF1_hist_chap) | 4 | ILE A 9ARG A 108THR A 43LEU A 42 | None | 0.90A | 3abkA-2idcA:undetectable3abkJ-2idcA:undetectable | 3abkA-2idcA:13.973abkJ-2idcA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j3z | C2 TOXIN COMPONENT I (Clostridiumbotulinum) |
PF03496(ADPrib_exo_Tox) | 4 | LEU A 89ARG A 28THR A 31LEU A 33 | None | 0.89A | 3abkA-2j3zA:undetectable3abkJ-2j3zA:undetectable | 3abkA-2j3zA:19.363abkJ-2j3zA:12.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jjy | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE (Francisellatularensis) |
PF13561(adh_short_C2) | 4 | LEU A 73ARG A 131MET A 133LEU A 84 | None | 0.92A | 3abkA-2jjyA:undetectable3abkJ-2jjyA:undetectable | 3abkA-2jjyA:19.533abkJ-2jjyA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jzn | MANNOSE-SPECIFICPHOSPHOTRANSFERASEENZYME IIA COMPONENT (Escherichiacoli) |
PF03610(EIIA-man) | 4 | ILE A 3LEU A 114PHE A 111LEU A 65 | None | 0.86A | 3abkA-2jznA:undetectable3abkJ-2jznA:undetectable | 3abkA-2jznA:15.943abkJ-2jznA:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kbq | HARMONIN (Homo sapiens) |
no annotation | 4 | ILE A 50LEU A 58TYR A 74LEU A 30 | None | 0.83A | 3abkA-2kbqA:undetectable3abkJ-2kbqA:undetectable | 3abkA-2kbqA:8.843abkJ-2kbqA:23.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2klt | SODIUM/CALCIUMEXCHANGER 1 (Canis lupus) |
PF03160(Calx-beta) | 4 | LEU A 589PHE A 587ARG A 574MET A 521 | None | 0.90A | 3abkA-2kltA:undetectable3abkJ-2kltA:undetectable | 3abkA-2kltA:13.583abkJ-2kltA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2la7 | UNCHARACTERIZEDPROTEIN (Paraburkholderiaxenovorans) |
PF03724(META) | 4 | LEU A 112ARG A 117THR A 137LEU A 138 | None | 0.93A | 3abkA-2la7A:undetectable3abkJ-2la7A:undetectable | 3abkA-2la7A:14.143abkJ-2la7A:15.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lez | SECRETED EFFECTORPROTEIN PIPB2 (Salmonellaenterica) |
no annotation | 4 | PHE A 124MET A 61THR A 60LEU A 57 | None | 0.90A | 3abkA-2lezA:undetectable3abkJ-2lezA:undetectable | 3abkA-2lezA:13.683abkJ-2lezA:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nlw | EUKARYOTICTRANSLATIONINITIATION FACTOR 3SUBUNIT 9 (Homo sapiens) |
PF00076(RRM_1) | 4 | ILE A 38PHE A 42THR A 91LEU A 86 | None | 0.94A | 3abkA-2nlwA:undetectable3abkJ-2nlwA:undetectable | 3abkA-2nlwA:12.553abkJ-2nlwA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o6q | VARIABLE LYMPHOCYTERECEPTOR A (Eptatretusburgeri) |
PF13855(LRR_8) | 4 | ILE A 53PHE A 79THR A 97LEU A 95 | None | 0.93A | 3abkA-2o6qA:undetectable3abkJ-2o6qA:undetectable | 3abkA-2o6qA:18.293abkJ-2o6qA:14.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ozg | GCN5-RELATEDN-ACETYLTRANSFERASE (Trichormusvariabilis) |
PF13527(Acetyltransf_9)PF13530(SCP2_2) | 4 | ILE A 25LEU A 22ARG A 54LEU A 99 | None | 0.91A | 3abkA-2ozgA:undetectable3abkJ-2ozgA:undetectable | 3abkA-2ozgA:21.723abkJ-2ozgA:9.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p0d | RHOGTPASE-ACTIVATINGPROTEIN 9 (Homo sapiens) |
PF00169(PH) | 4 | ILE A 405LEU A 390THR A 353LEU A 352 | None | 0.78A | 3abkA-2p0dA:undetectable3abkJ-2p0dA:undetectable | 3abkA-2p0dA:12.673abkJ-2p0dA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p3g | MAP KINASE-ACTIVATEDPROTEIN KINASE 2 (Homo sapiens) |
PF00069(Pkinase) | 4 | ILE X 252MET X 356THR X 357LEU X 360 | None | 0.80A | 3abkA-2p3gX:undetectable3abkJ-2p3gX:undetectable | 3abkA-2p3gX:19.813abkJ-2p3gX:13.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p3x | POLYPHENOL OXIDASE,CHLOROPLAST (Vitis vinifera) |
PF00264(Tyrosinase)PF12142(PPO1_DWL) | 4 | LEU A 128PHE A 137TYR A 58LEU A 163 | None | 0.78A | 3abkA-2p3xA:undetectable3abkJ-2p3xA:undetectable | 3abkA-2p3xA:19.173abkJ-2p3xA:10.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q7s | N-FORMYLGLUTAMATEAMIDOHYDROLASE (Cupriaviduspinatubonensis) |
PF05013(FGase) | 4 | ILE A 250PHE A 192ARG A 272THR A 275 | None | 0.91A | 3abkA-2q7sA:undetectable3abkJ-2q7sA:undetectable | 3abkA-2q7sA:19.193abkJ-2q7sA:12.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qby | CELL DIVISIONCONTROL PROTEIN 6HOMOLOG 1 (Sulfolobussolfataricus) |
PF09079(Cdc6_C)PF13401(AAA_22) | 4 | ILE A 175PHE A 177ARG A 165LEU A 130 | None | 0.93A | 3abkA-2qbyA:undetectable3abkJ-2qbyA:undetectable | 3abkA-2qbyA:20.303abkJ-2qbyA:9.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qk4 | TRIFUNCTIONAL PURINEBIOSYNTHETIC PROTEINADENOSINE-3 (Homo sapiens) |
PF01071(GARS_A)PF02843(GARS_C)PF02844(GARS_N) | 4 | ILE A 272PHE A 203THR A 16LEU A 17 | None | 0.89A | 3abkA-2qk4A:undetectable3abkJ-2qk4A:undetectable | 3abkA-2qk4A:22.523abkJ-2qk4A:9.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uvf | EXOPOLYGALACTURONASE (Yersiniaenterocolitica) |
PF00295(Glyco_hydro_28)PF12708(Pectate_lyase_3) | 4 | PHE A 347MET A 334THR A 335LEU A 336 | None | 0.86A | 3abkA-2uvfA:undetectable3abkJ-2uvfA:undetectable | 3abkA-2uvfA:22.563abkJ-2uvfA:8.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ws9 | P1 (Equine rhinitisA virus) |
no annotation | 4 | LEU 1 84PHE 1 156THR 1 198LEU 1 197 | None | 0.89A | 3abkA-2ws91:undetectable3abkJ-2ws91:undetectable | 3abkA-2ws91:19.073abkJ-2ws91:10.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wy0 | ANGIOTENSINOGEN (Mus musculus) |
PF00079(Serpin) | 4 | LEU C 309ARG C 345THR C 423LEU C 424 | None | 0.83A | 3abkA-2wy0C:undetectable3abkJ-2wy0C:undetectable | 3abkA-2wy0C:21.213abkJ-2wy0C:8.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wyh | ALPHA-MANNOSIDASE (Streptococcuspyogenes) |
PF01074(Glyco_hydro_38)PF07748(Glyco_hydro_38C)PF09261(Alpha-mann_mid) | 5 | ILE A 614LEU A 646PHE A 612THR A 753LEU A 755 | None | 1.23A | 3abkA-2wyhA:2.13abkJ-2wyhA:undetectable | 3abkA-2wyhA:20.263abkJ-2wyhA:4.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x3c | TOXIC EXTRACELLULARENDOPEPTIDASE (Aeromonassalmonicida) |
PF14521(Aspzincin_M35) | 4 | LEU A 67PHE A 68THR A 43LEU A 44 | None | 0.82A | 3abkA-2x3cA:1.53abkJ-2x3cA:undetectable | 3abkA-2x3cA:20.643abkJ-2x3cA:10.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xut | PROTON/PEPTIDESYMPORTER FAMILYPROTEIN (Shewanellaoneidensis) |
PF00854(PTR2) | 4 | ILE A 301LEU A 304PHE A 305LEU A 373 | None | 0.90A | 3abkA-2xutA:2.13abkJ-2xutA:undetectable | 3abkA-2xutA:23.163abkJ-2xutA:8.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xwb | COMPLEMENT C3BALPHA' CHAIN (Homo sapiens) |
PF00207(A2M)PF01759(NTR)PF07677(A2M_recep)PF07678(A2M_comp)PF10569(Thiol-ester_cl) | 4 | ILE B 958LEU B1276THR B 924LEU B 925 | None | 0.93A | 3abkA-2xwbB:2.33abkJ-2xwbB:undetectable | 3abkA-2xwbB:20.773abkJ-2xwbB:5.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xxl | GRAM-POSITIVESPECIFIC SERINEPROTEASE, ISOFORM B (Drosophilamelanogaster) |
PF00089(Trypsin)PF12032(CLIP) | 5 | LEU A 244PHE A 104ARG A 156MET A 372LEU A 226 | None | 1.10A | 3abkA-2xxlA:undetectable3abkJ-2xxlA:undetectable | 3abkA-2xxlA:19.173abkJ-2xxlA:10.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y24 | XYLANASE (Dickeyachrysanthemi) |
PF02055(Glyco_hydro_30)PF17189(Glyco_hydro_30C) | 4 | ILE A 75LEU A 77THR A 60LEU A 59 | None | 0.79A | 3abkA-2y24A:undetectable3abkJ-2y24A:undetectable | 3abkA-2y24A:22.633abkJ-2y24A:8.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y69 | CYTOCHROME C OXIDASEPOLYPEPTIDE 7A1 (Bos taurus) |
PF02238(COX7a) | 5 | TYR J 32ARG J 33MET J 36THR J 37LEU J 40 | None | 0.70A | 3abkA-2y69J:undetectable3abkJ-2y69J:7.9 | 3abkA-2y69J:10.313abkJ-2y69J:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yhe | SEC-ALKYL SULFATASE (Pseudomonas sp.DSM 6611) |
PF00753(Lactamase_B)PF14863(Alkyl_sulf_dimr)PF14864(Alkyl_sulf_C) | 4 | ARG A 588MET A 570THR A 571LEU A 572 | None | 0.93A | 3abkA-2yheA:undetectable3abkJ-2yheA:undetectable | 3abkA-2yheA:20.413abkJ-2yheA:7.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yhe | SEC-ALKYL SULFATASE (Pseudomonas sp.DSM 6611) |
PF00753(Lactamase_B)PF14863(Alkyl_sulf_dimr)PF14864(Alkyl_sulf_C) | 4 | ILE A 617PHE A 646THR A 606LEU A 635 | None | 0.81A | 3abkA-2yheA:undetectable3abkJ-2yheA:undetectable | 3abkA-2yheA:20.413abkJ-2yheA:7.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ze0 | ALPHA-GLUCOSIDASE (Geobacillus sp.HTA-462) |
PF00128(Alpha-amylase)PF16657(Malt_amylase_C) | 4 | ILE A 193LEU A 97PHE A 196MET A 184 | None | 0.79A | 3abkA-2ze0A:undetectable3abkJ-2ze0A:undetectable | 3abkA-2ze0A:19.593abkJ-2ze0A:7.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zgk | ANTI-TUMOR LECTIN (Agrocybeaegerita) |
PF00337(Gal-bind_lectin) | 4 | ILE A 115PHE A 93THR A 46LEU A 47 | None | 0.90A | 3abkA-2zgkA:undetectable3abkJ-2zgkA:undetectable | 3abkA-2zgkA:15.563abkJ-2zgkA:12.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ziu | MUS81 PROTEIN (Danio rerio) |
PF02732(ERCC4) | 4 | TYR A 471MET A 475THR A 476LEU A 479 | None | 0.81A | 3abkA-2ziuA:undetectable3abkJ-2ziuA:undetectable | 3abkA-2ziuA:18.553abkJ-2ziuA:10.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zsg | AMINOPEPTIDASE P,PUTATIVE (Thermotogamaritima) |
PF00557(Peptidase_M24)PF01321(Creatinase_N) | 4 | ILE A 230MET A 177THR A 176LEU A 173 | None | 0.93A | 3abkA-2zsgA:undetectable3abkJ-2zsgA:undetectable | 3abkA-2zsgA:20.793abkJ-2zsgA:10.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zts | PUTATIVEUNCHARACTERIZEDPROTEIN PH0186 (Pyrococcushorikoshii) |
PF06745(ATPase) | 4 | ILE A 127PHE A 123THR A 178LEU A 177 | None | 0.72A | 3abkA-2ztsA:undetectable3abkJ-2ztsA:undetectable | 3abkA-2ztsA:17.813abkJ-2ztsA:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b2d | CD180 ANTIGEN (Homo sapiens) |
PF00560(LRR_1)PF13855(LRR_8) | 4 | ILE A 352LEU A 377THR A 348LEU A 372 | None | 0.85A | 3abkA-3b2dA:undetectable3abkJ-3b2dA:undetectable | 3abkA-3b2dA:20.653abkJ-3b2dA:7.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b46 | AMINOTRANSFERASEBNA3 (Saccharomycescerevisiae) |
PF00155(Aminotran_1_2) | 4 | ILE A 343LEU A 347PHE A 344LEU A 396 | None | 0.84A | 3abkA-3b46A:undetectable3abkJ-3b46A:undetectable | 3abkA-3b46A:22.553abkJ-3b46A:9.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b4u | DIHYDRODIPICOLINATESYNTHASE (Agrobacteriumfabrum) |
PF00701(DHDPS) | 4 | ILE A 66ARG A 100THR A 42LEU A 43 | None | 0.85A | 3abkA-3b4uA:undetectable3abkJ-3b4uA:undetectable | 3abkA-3b4uA:20.993abkJ-3b4uA:13.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b7y | E3 UBIQUITIN-PROTEINLIGASE NEDD4 (Homo sapiens) |
PF00168(C2) | 5 | PHE A 189ARG A 124MET A 248THR A 249LEU A 213 | None | 1.32A | 3abkA-3b7yA:undetectable3abkJ-3b7yA:undetectable | 3abkA-3b7yA:13.393abkJ-3b7yA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bn1 | PEROSAMINESYNTHETASE (Caulobactervibrioides) |
PF01041(DegT_DnrJ_EryC1) | 4 | ILE A 312TYR A 261THR A 289LEU A 346 | None | 0.91A | 3abkA-3bn1A:undetectable3abkJ-3bn1A:undetectable | 3abkA-3bn1A:21.123abkJ-3bn1A:11.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c9b | VACUOLAR PROTEINSORTING-ASSOCIATEDPROTEIN 75 (Saccharomycescerevisiae) |
PF00956(NAP) | 4 | ILE A 80LEU A 62ARG A 73LEU A 200 | None | 0.68A | 3abkA-3c9bA:undetectable3abkJ-3c9bA:undetectable | 3abkA-3c9bA:16.413abkJ-3c9bA:12.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dby | UNCHARACTERIZEDPROTEIN (Bacillus cereus) |
PF11155(DUF2935) | 4 | LEU A 53PHE A 50ARG A 77LEU A 115 | None | 0.86A | 3abkA-3dbyA:4.33abkJ-3dbyA:undetectable | 3abkA-3dbyA:17.093abkJ-3dbyA:12.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dcp | HISTIDINOL-PHOSPHATASE (Listeriamonocytogenes) |
PF02811(PHP)PF13263(PHP_C) | 4 | LEU A 30PHE A 32TYR A 255THR A 271 | None | 0.73A | 3abkA-3dcpA:undetectable3abkJ-3dcpA:undetectable | 3abkA-3dcpA:19.373abkJ-3dcpA:12.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dy5 | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | ILE A 462ARG A 397THR A 395LEU A 410 | None | 0.86A | 3abkA-3dy5A:undetectable3abkJ-3dy5A:undetectable | 3abkA-3dy5A:17.953abkJ-3dy5A:4.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e0s | UNCHARACTERIZEDPROTEIN (Chlorobaculumtepidum) |
PF05235(CHAD) | 4 | PHE A 255TYR A 347MET A 351THR A 352 | None | 0.89A | 3abkA-3e0sA:2.93abkJ-3e0sA:undetectable | 3abkA-3e0sA:19.133abkJ-3e0sA:10.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e7f | 6-PHOSPHOGLUCONOLACTONASE (Trypanosomabrucei) |
PF01182(Glucosamine_iso) | 4 | ILE A 230LEU A 231THR A 219LEU A 255 | None | 0.76A | 3abkA-3e7fA:undetectable3abkJ-3e7fA:undetectable | 3abkA-3e7fA:19.653abkJ-3e7fA:12.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ehe | UDP-GLUCOSE4-EPIMERASE (GALE-1) (Archaeoglobusfulgidus) |
PF01370(Epimerase) | 4 | ILE A 205ARG A 164THR A 126LEU A 271 | None | 0.88A | 3abkA-3eheA:undetectable3abkJ-3eheA:undetectable | 3abkA-3eheA:17.733abkJ-3eheA:10.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f95 | BETA-GLUCOSIDASE (Pseudoalteromonassp. BB1) |
no annotation | 5 | ILE A 784PHE A 747ARG A 721MET A 720LEU A 718 | None | 1.49A | 3abkA-3f95A:undetectable3abkJ-3f95A:undetectable | 3abkA-3f95A:17.883abkJ-3f95A:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fdd | L-ASPARTATE-BETA-DECARBOXYLASE (Comamonastestosteroni) |
PF00155(Aminotran_1_2) | 4 | ILE A 475LEU A 483ARG A 516LEU A 423 | None | 0.93A | 3abkA-3fddA:undetectable3abkJ-3fddA:undetectable | 3abkA-3fddA:21.013abkJ-3fddA:8.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fg4 | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | ILE A 462ARG A 397THR A 395LEU A 410 | None | 0.77A | 3abkA-3fg4A:2.73abkJ-3fg4A:undetectable | 3abkA-3fg4A:20.563abkJ-3fg4A:8.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fss | HISTONE CHAPERONERTT106 (Saccharomycescerevisiae) |
PF08512(Rtt106) | 4 | ILE A 200MET A 158THR A 159LEU A 160 | None | 0.93A | 3abkA-3fssA:undetectable3abkJ-3fssA:undetectable | 3abkA-3fssA:19.043abkJ-3fssA:13.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gzy | BIPHENYL DIOXYGENASESUBUNIT BETA (Comamonastestosteroni) |
PF00866(Ring_hydroxyl_B) | 4 | ILE B 165LEU B 48ARG B 31LEU B 36 | None | 0.84A | 3abkA-3gzyB:undetectable3abkJ-3gzyB:undetectable | 3abkA-3gzyB:15.343abkJ-3gzyB:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h5t | TRANSCRIPTIONALREGULATOR, LACIFAMILY (Corynebacteriumglutamicum) |
PF00356(LacI)PF13377(Peripla_BP_3) | 4 | ILE A 147LEU A 152THR A 331LEU A 332 | None | 0.77A | 3abkA-3h5tA:undetectable3abkJ-3h5tA:undetectable | 3abkA-3h5tA:21.023abkJ-3h5tA:9.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7a | SHORT CHAINDEHYDROGENASE (Rhodopseudomonaspalustris) |
PF00106(adh_short) | 4 | ILE A 135PHE A 137THR A 70LEU A 73 | ILE A 135 ( 0.6A)PHE A 137 ( 1.3A)THR A 70 ( 0.8A)LEU A 73 ( 0.5A) | 0.89A | 3abkA-3h7aA:undetectable3abkJ-3h7aA:undetectable | 3abkA-3h7aA:18.893abkJ-3h7aA:11.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hi8 | PROLIFERATING CELLNUCLEAR ANTIGEN PCNA (Haloferaxvolcanii) |
PF00705(PCNA_N)PF02747(PCNA_C) | 4 | LEU A 15ARG A 37THR A 50LEU A 51 | None | 0.93A | 3abkA-3hi8A:undetectable3abkJ-3hi8A:undetectable | 3abkA-3hi8A:20.533abkJ-3hi8A:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hn5 | PUTATIVE EXPORTEDPROTEIN BF0290 (Bacteroidesfragilis) |
PF12866(DUF3823) | 4 | ILE A 105ARG A 36THR A 34LEU A 33 | None | 0.84A | 3abkA-3hn5A:undetectable3abkJ-3hn5A:undetectable | 3abkA-3hn5A:17.123abkJ-3hn5A:14.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i2m | ORF59 (Humangammaherpesvirus8) |
PF04929(Herpes_DNAp_acc) | 5 | LEU X 98PHE X 99ARG X 61THR X 45LEU X 66 | None | 1.36A | 3abkA-3i2mX:undetectable3abkJ-3i2mX:undetectable | 3abkA-3i2mX:20.623abkJ-3i2mX:12.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iqd | OCTOPINEDEHYDROGENASE (Pecten maximus) |
PF02317(Octopine_DH) | 4 | LEU B 184PHE B 194THR B 16LEU B 17 | None | 0.92A | 3abkA-3iqdB:undetectable3abkJ-3iqdB:undetectable | 3abkA-3iqdB:21.053abkJ-3iqdB:9.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ix1 | N-FORMYL-4-AMINO-5-AMINOMETHYL-2-METHYLPYRIMIDINE BINDINGPROTEIN (Bacillushalodurans) |
PF09084(NMT1) | 5 | ILE A 66LEU A 37PHE A 68THR A 262LEU A 260 | None | 1.04A | 3abkA-3ix1A:undetectable3abkJ-3ix1A:undetectable | 3abkA-3ix1A:19.803abkJ-3ix1A:12.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j4p | CAPSID PROTEIN VP1 (Adeno-associatedvirus) |
PF00740(Parvo_coat) | 4 | ILE A 374LEU A 249ARG A 245LEU A 317 | None | 0.82A | 3abkA-3j4pA:undetectable3abkJ-3j4pA:undetectable | 3abkA-3j4pA:22.363abkJ-3j4pA:9.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j4u | MAJOR CAPSID PROTEIN (Bordetellavirus BPP1) |
no annotation | 4 | ILE A 38LEU A 130PHE A 131LEU A 183 | None | 0.88A | 3abkA-3j4uA:undetectable3abkJ-3j4uA:undetectable | 3abkA-3j4uA:21.073abkJ-3j4uA:13.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jzd | IRON-CONTAININGALCOHOLDEHYDROGENASE (Cupriaviduspinatubonensis) |
PF00465(Fe-ADH) | 4 | ILE A 343LEU A 346ARG A 322LEU A 248 | None | 0.92A | 3abkA-3jzdA:1.93abkJ-3jzdA:undetectable | 3abkA-3jzdA:22.153abkJ-3jzdA:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k13 | 5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINEMETHYLTRANSFERASE (Bacteroidesthetaiotaomicron) |
PF00809(Pterin_bind) | 4 | ARG A 407MET A 410THR A 411LEU A 414 | None | 0.66A | 3abkA-3k13A:undetectable3abkJ-3k13A:undetectable | 3abkA-3k13A:20.203abkJ-3k13A:11.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k1r | HARMONIN (Homo sapiens) |
PF00595(PDZ) | 4 | ILE A 50LEU A 58TYR A 74LEU A 30 | None | 0.87A | 3abkA-3k1rA:undetectable3abkJ-3k1rA:undetectable | 3abkA-3k1rA:14.453abkJ-3k1rA:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kfu | ASPARTYL/GLUTAMYL-TRNA(ASN/GLN)AMIDOTRANSFERASESUBUNIT B (Thermusthermophilus) |
PF02637(GatB_Yqey)PF02934(GatB_N) | 4 | ILE F 166LEU F 163ARG F 111LEU F 153 | None | 0.93A | 3abkA-3kfuF:undetectable3abkJ-3kfuF:undetectable | 3abkA-3kfuF:18.693abkJ-3kfuF:10.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kl7 | PUTATIVEMETAL-DEPENDENTHYDROLASE (Parabacteroidesdistasonis) |
PF13483(Lactamase_B_3) | 4 | ILE A 101MET A 128THR A 157LEU A 156 | NoneNoneGOL A 306 (-4.7A)None | 0.90A | 3abkA-3kl7A:undetectable3abkJ-3kl7A:undetectable | 3abkA-3kl7A:16.473abkJ-3kl7A:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kuq | RHOGTPASE-ACTIVATINGPROTEIN 7 (Homo sapiens) |
PF00620(RhoGAP) | 4 | ILE A1186PHE A1170ARG A1198LEU A1205 | None | 0.84A | 3abkA-3kuqA:undetectable3abkJ-3kuqA:undetectable | 3abkA-3kuqA:17.513abkJ-3kuqA:14.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kzx | HAD-SUPERFAMILYHYDROLASE, SUBFAMILYIA, VARIANT 1 (Ehrlichiachaffeensis) |
PF13419(HAD_2) | 5 | ILE A 180LEU A 192PHE A 194ARG A 201LEU A 207 | None | 1.34A | 3abkA-3kzxA:undetectable3abkJ-3kzxA:undetectable | 3abkA-3kzxA:17.443abkJ-3kzxA:11.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3muu | STRUCTURALPOLYPROTEIN (Sindbis virus) |
PF00943(Alpha_E2_glycop)PF01589(Alpha_E1_glycop) | 4 | ILE A 283ARG A 298THR A 296LEU A 295 | None | 0.82A | 3abkA-3muuA:undetectable3abkJ-3muuA:undetectable | 3abkA-3muuA:21.453abkJ-3muuA:6.16 |