SIMILAR PATTERNS OF AMINO ACIDS FOR 3ABK_B_CHDB1085_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2e | ELONGATION FACTOR TU(EF-TU) (Bos taurus) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2) | 5 | GLY A 172GLN A 170THR A 437PHE A 206GLY A 207 | None | 1.36A | 3abkA-1d2eA:0.03abkB-1d2eA:0.03abkT-1d2eA:0.0 | 3abkA-1d2eA:21.963abkB-1d2eA:19.613abkT-1d2eA:12.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k5s | PENICILLIN G ACYLASEBETA SUBUNIT (Escherichiacoli) |
PF01804(Penicil_amidase) | 5 | MET B 485GLU B 482THR B 481PHE B 531GLY B 532 | None | 1.20A | 3abkA-1k5sB:0.73abkB-1k5sB:0.03abkT-1k5sB:0.0 | 3abkA-1k5sB:20.533abkB-1k5sB:17.453abkT-1k5sB:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x87 | UROCANASE PROTEIN (Geobacillusstearothermophilus) |
PF01175(Urocanase)PF17391(Urocanase_N)PF17392(Urocanase_C) | 5 | GLN A 177THR A 257ARG A 197ARG A 201GLY A 234 | NoneNoneNAD A 600 (-3.9A)NoneNone | 1.48A | 3abkA-1x87A:1.13abkB-1x87A:0.03abkT-1x87A:0.0 | 3abkA-1x87A:20.443abkB-1x87A:18.233abkT-1x87A:9.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2buf | ACETYLGLUTAMATEKINASE (Pseudomonasaeruginosa) |
PF00696(AA_kinase) | 5 | GLY A 67GLN A 71GLU A 40ARG A 90GLY A 105 | NLG A1302 (-3.3A)NoneNoneNLG A1302 (-4.3A)None | 1.29A | 3abkA-2bufA:0.73abkB-2bufA:0.03abkT-2bufA:0.0 | 3abkA-2bufA:22.063abkB-2bufA:21.693abkT-2bufA:14.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ddt | SPHINGOMYELINPHOSPHODIESTERASE (Bacillus cereus) |
PF03372(Exo_endo_phos) | 5 | GLY A 102GLN A 116THR A 75PHE A 133GLY A 149 | None | 1.25A | 3abkA-2ddtA:undetectable3abkB-2ddtA:0.03abkT-2ddtA:0.0 | 3abkA-2ddtA:18.603abkB-2ddtA:19.033abkT-2ddtA:13.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qua | EXTRACELLULAR LIPASE (Serratiamarcescens) |
no annotation | 5 | GLY A 181GLU A 112THR A 117THR A 113GLY A 174 | None | 1.40A | 3abkA-2quaA:0.03abkB-2quaA:0.53abkT-2quaA:0.0 | 3abkA-2quaA:21.913abkB-2quaA:15.423abkT-2quaA:9.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xhy | 6-PHOSPHO-BETA-GLUCOSIDASE BGLA (Escherichiacoli) |
PF00232(Glyco_hydro_1) | 5 | GLY A 381TRP A 351THR A 435THR A 434GLY A 350 | NoneNoneNoneSO4 A1481 (-4.0A)None | 1.38A | 3abkA-2xhyA:0.03abkB-2xhyA:0.03abkT-2xhyA:0.0 | 3abkA-2xhyA:20.623abkB-2xhyA:18.603abkT-2xhyA:10.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3al8 | SEMAPHORIN-6A (Mus musculus) |
PF01403(Sema)PF01437(PSI) | 5 | MET A 488GLY A 489THR A 300ARG A 486GLY A 441 | None | 1.30A | 3abkA-3al8A:undetectable3abkB-3al8A:0.03abkT-3al8A:0.0 | 3abkA-3al8A:21.013abkB-3al8A:17.633abkT-3al8A:8.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bt7 | TRNA(URACIL-5-)-METHYLTRANSFERASE (Escherichiacoli) |
PF05958(tRNA_U5-meth_tr) | 5 | MET A 179GLU A 170ARG A 230PHE A 224GLY A 222 | None | 1.40A | 3abkA-3bt7A:0.03abkB-3bt7A:0.03abkT-3bt7A:0.0 | 3abkA-3bt7A:20.943abkB-3bt7A:20.403abkT-3bt7A:13.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ce6 | ADENOSYLHOMOCYSTEINASE (Mycobacteriumtuberculosis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLY A 359THR A 269ARG A 406PHE A 96GLY A 411 | None | 1.24A | 3abkA-3ce6A:0.43abkB-3ce6A:undetectable3abkT-3ce6A:undetectable | 3abkA-3ce6A:22.593abkB-3ce6A:18.093abkT-3ce6A:12.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cvr | INVASION PLASMIDANTIGEN (Shigellaflexneri) |
PF12468(TTSSLRR)PF14496(NEL) | 5 | MET A 402GLY A 399THR A 392ARG A 375GLY A 484 | None | 1.41A | 3abkA-3cvrA:2.13abkB-3cvrA:undetectable3abkT-3cvrA:undetectable | 3abkA-3cvrA:22.783abkB-3cvrA:18.503abkT-3cvrA:9.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgb | UNCHARACTERIZEDPROTEIN Q89ZH8_BACTN (Bacteroidesthetaiotaomicron) |
PF10282(Lactonase) | 5 | GLY A 153THR A 129ARG A 112PHE A 104GLY A 83 | None | 1.30A | 3abkA-3fgbA:undetectable3abkB-3fgbA:undetectable3abkT-3fgbA:undetectable | 3abkA-3fgbA:20.443abkB-3fgbA:21.473abkT-3fgbA:13.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k55 | BETA-HEMOLYSIN (Staphylococcusaureus) |
PF03372(Exo_endo_phos) | 5 | GLY A 101GLN A 115THR A 75PHE A 132GLY A 148 | None | 1.28A | 3abkA-3k55A:undetectable3abkB-3k55A:undetectable3abkT-3k55A:undetectable | 3abkA-3k55A:19.583abkB-3k55A:18.913abkT-3k55A:14.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s9b | VIPERA RUSSELLIPROTEINASE RVV-VGAMMA (Daboiasiamensis) |
PF00089(Trypsin) | 5 | GLY A 18ARG A 137ARG A 135PHE A 161GLY A 184 | None | 1.14A | 3abkA-3s9bA:undetectable3abkB-3s9bA:undetectable3abkT-3s9bA:undetectable | 3abkA-3s9bA:19.003abkB-3s9bA:21.013abkT-3s9bA:15.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vrb | FLAVOPROTEIN SUBUNITOF COMPLEX IIIRON-SULFUR SUBUNITOF SUCCINATEDEHYDROGENASE (Ascaris suum;Ascaris suum) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C)PF13085(Fer2_3)PF13534(Fer4_17) | 5 | GLN A 84GLU B 91THR A 366ARG A 320GLY A 279 | NoneFAD A 702 ( 4.4A)NoneFUM A 701 (-3.2A)None | 1.39A | 3abkA-3vrbA:1.63abkB-3vrbA:undetectable3abkT-3vrbA:undetectable | 3abkA-3vrbA:22.273abkB-3vrbA:15.623abkT-3vrbA:8.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wy7 | 8-AMINO-7-OXONONANOATE SYNTHASE (Mycolicibacteriumsmegmatis) |
PF00155(Aminotran_1_2) | 5 | GLY A 214GLU A 201THR A 230THR A 231GLY A 94 | None | 1.37A | 3abkA-3wy7A:undetectable3abkB-3wy7A:undetectable3abkT-3wy7A:undetectable | 3abkA-3wy7A:21.193abkB-3wy7A:19.493abkT-3wy7A:12.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cgy | DNA TOPOISOMERASE3-ALPHA (Homo sapiens) |
PF01131(Topoisom_bac)PF01751(Toprim) | 5 | MET A 566GLY A 565THR A 544PHE A 559GLY A 552 | None | 1.41A | 3abkA-4cgyA:1.93abkB-4cgyA:undetectable3abkT-4cgyA:undetectable | 3abkA-4cgyA:20.213abkB-4cgyA:12.963abkT-4cgyA:9.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j9u | TRK SYSTEM POTASSIUMUPTAKE PROTEIN TRKH (Vibrioparahaemolyticus) |
PF02386(TrkH) | 5 | MET A 356GLY A 355THR A 110THR A 112PHE A 466 | None | 1.38A | 3abkA-4j9uA:4.53abkB-4j9uA:undetectable3abkT-4j9uA:undetectable | 3abkA-4j9uA:23.603abkB-4j9uA:18.893abkT-4j9uA:10.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lls | GERANYLTRANSTRANSFERASE (Roseobacterdenitrificans) |
PF00348(polyprenyl_synt) | 5 | MET A 149GLN A 175THR A 172ARG A 44GLY A 184 | GST A 302 ( 4.1A)NoneNoneIPE A 301 (-3.1A)None | 1.48A | 3abkA-4llsA:2.03abkB-4llsA:undetectable3abkT-4llsA:undetectable | 3abkA-4llsA:20.313abkB-4llsA:22.933abkT-4llsA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q1q | ADHESIN/INVASIN TIBAAUTOTRANSPORTER (Escherichiacoli) |
PF16168(AIDA) | 5 | GLN A 204THR A 215THR A 234ARG A 207GLY A 229 | NoneNoneNone289 A 414 ( 3.6A)None | 1.31A | 3abkA-4q1qA:undetectable3abkB-4q1qA:undetectable3abkT-4q1qA:undetectable | 3abkA-4q1qA:21.893abkB-4q1qA:19.413abkT-4q1qA:12.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qdg | PUTATIVE ADHESIN (Bacteroidesthetaiotaomicron) |
PF08842(Mfa2) | 5 | MET A 175THR A 67ARG A 253PHE A 119GLY A 153 | None | 1.34A | 3abkA-4qdgA:undetectable3abkB-4qdgA:undetectable3abkT-4qdgA:undetectable | 3abkA-4qdgA:20.493abkB-4qdgA:23.203abkT-4qdgA:13.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gq0 | EPITHIOSPECIFIERPROTEIN (Arabidopsisthaliana) |
no annotation | 5 | GLY B 39THR B 73ARG B 94PHE B 100GLY B 92 | None | 1.22A | 3abkA-5gq0B:undetectable3abkB-5gq0B:undetectable3abkT-5gq0B:undetectable | 3abkA-5gq0B:20.153abkB-5gq0B:18.623abkT-5gq0B:12.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yb7 | L-AMINO ACIDOXIDASE/MONOOXYGENASE (Pseudomonas sp.AIU 813) |
no annotation | 5 | GLY A 519GLU A 518THR A 16THR A 252PHE A 22 | None | 1.47A | 3abkA-5yb7A:undetectable3abkB-5yb7A:undetectable3abkT-5yb7A:undetectable | 3abkA-5yb7A:undetectable3abkB-5yb7A:undetectable3abkT-5yb7A:undetectable |