SIMILAR PATTERNS OF AMINO ACIDS FOR 3A51_D_VDYD6178_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 13pk | 3-PHOSPHOGLYCERATEKINASE (Trypanosomabrucei) |
PF00162(PGK) | 5 | ILE A 180MET A 71ILE A 154VAL A 58LEU A 131 | None | 1.19A | 3a51D-13pkA:0.0 | 3a51D-13pkA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h6d | PRECURSOR FORM OFGLUCOSE-FRUCTOSEOXIDOREDUCTASE (Zymomonasmobilis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | MET A 342ILE A 353ASN A 272LEU A 340ILE A 223 | None | 1.21A | 3a51D-1h6dA:0.0 | 3a51D-1h6dA:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hm6 | ANNEXIN 1 (Sus scrofa) |
PF00191(Annexin) | 5 | LEU A 256ILE A 260THR A 265VAL A 268LEU A 225 | None | 1.21A | 3a51D-1hm6A:0.0 | 3a51D-1hm6A:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1io0 | TROPOMODULIN (Gallus gallus) |
no annotation | 5 | THR A 234ILE A 264ASN A 201VAL A 273LEU A 285 | None | 1.03A | 3a51D-1io0A:0.0 | 3a51D-1io0A:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jmo | HEPARIN COFACTOR II (Homo sapiens) |
PF00079(Serpin) | 5 | ILE A 270LEU A 205ILE A 408VAL A 158LEU A 398 | None | 0.95A | 3a51D-1jmoA:0.0 | 3a51D-1jmoA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nbw | GLYCEROL DEHYDRATASEREACTIVASE ALPHASUBUNIT (Klebsiellapneumoniae) |
PF08841(DDR) | 5 | THR A 37ILE A 46LEU A 50VAL A 387LEU A 72 | None | 1.04A | 3a51D-1nbwA:0.0 | 3a51D-1nbwA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ne7 | GLUCOSAMINE-6-PHOSPHATE ISOMERASE (Homo sapiens) |
PF01182(Glucosamine_iso) | 5 | ILE A 20MET A 89LEU A 52VAL A 238LEU A 202 | None | 1.24A | 3a51D-1ne7A:0.0 | 3a51D-1ne7A:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1no7 | MAJOR CAPSID PROTEIN (Humanalphaherpesvirus1) |
PF03122(Herpes_MCP) | 5 | ILE A 937LEU A 939ILE A 949VAL A 835LEU A 629 | None | 1.23A | 3a51D-1no7A:0.0 | 3a51D-1no7A:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nrz | PTS SYSTEM,SORBOSE-SPECIFIC IIBCOMPONENT (Klebsiellapneumoniae) |
PF03830(PTSIIB_sorb) | 5 | MET A 108ILE A 9ILE A 154VAL A 139LEU A 134 | None | 1.20A | 3a51D-1nrzA:0.0 | 3a51D-1nrzA:16.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o20 | GAMMA-GLUTAMYLPHOSPHATE REDUCTASE (Thermotogamaritima) |
PF00171(Aldedh) | 5 | THR A 292ILE A 275LEU A 261ILE A 316THR A 249 | None | 1.18A | 3a51D-1o20A:undetectable | 3a51D-1o20A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r3n | BETA-ALANINESYNTHASE (Lachanceakluyveri) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | ILE A 432ASN A 422LEU A 128ILE A 127LEU A 40 | None | 1.16A | 3a51D-1r3nA:undetectable | 3a51D-1r3nA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s3d | ARSENATE REDUCTASE (Escherichiacoli) |
PF03960(ArsC) | 5 | ILE A 92LEU A 58ILE A 48THR A 103PRO A 39 | None | 1.16A | 3a51D-1s3dA:undetectable | 3a51D-1s3dA:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1suv | TRANSFERRIN RECEPTORPROTEIN 1 (Homo sapiens) |
PF02225(PA)PF04253(TFR_dimer)PF04389(Peptidase_M28) | 5 | MET A 635ILE A 632LEU A 637THR A 739LEU A 712 | None | 1.18A | 3a51D-1suvA:undetectable | 3a51D-1suvA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yw1 | PROTEIN YTNJ (Bacillussubtilis) |
PF00296(Bac_luciferase) | 5 | ILE A 374LEU A 407ILE A 404VAL A 275PRO A 273 | None | 1.15A | 3a51D-1yw1A:undetectable | 3a51D-1yw1A:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zfj | INOSINEMONOPHOSPHATEDEHYDROGENASE (Streptococcuspyogenes) |
PF00478(IMPDH)PF00571(CBS) | 5 | ILE A 48ASN A 282ILE A 346PRO A 47LEU A 356 | NoneIMP A 500 ( 4.5A)NoneNoneNone | 1.17A | 3a51D-1zfjA:undetectable | 3a51D-1zfjA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a7n | L(+)-MANDELATEDEHYDROGENASE (Pseudomonasputida;Spinaciaoleracea) |
PF01070(FMN_dh) | 5 | ILE A 345LEU A 337VAL A 304PRO A 74LEU A 75 | None | 1.09A | 3a51D-2a7nA:undetectable | 3a51D-2a7nA:24.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aaz | THYMIDYLATE SYNTHASE (Cryptococcusneoformans) |
PF00303(Thymidylat_synt) | 5 | ILE A 228LEU A 251ILE A 250PRO A 64LEU A 58 | None | 1.10A | 3a51D-2aazA:undetectable | 3a51D-2aazA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b2i | AMMONIUM TRANSPORTER (Archaeoglobusfulgidus) |
PF00909(Ammonium_transp) | 5 | ASN A 35MET A 39LEU A 104VAL A 363LEU A 369 | None | 1.24A | 3a51D-2b2iA:undetectable | 3a51D-2b2iA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bg9 | ACETYLCHOLINERECEPTOR PROTEIN,GAMMA CHAIN (Torpedomarmorata) |
PF02931(Neur_chan_LBD)PF02932(Neur_chan_memb) | 5 | ILE E 55LEU E 34ILE E 208VAL E 30PRO E 87 | None | 1.22A | 3a51D-2bg9E:2.6 | 3a51D-2bg9E:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c5u | RNA LIGASE (Escherichiavirus T4) |
PF09511(RNA_lig_T4_1) | 5 | ILE A 217LYS A 234LEU A 79ILE A 88PRO A 214 | None | 1.13A | 3a51D-2c5uA:undetectable | 3a51D-2c5uA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cun | PHOSPHOGLYCERATEKINASE (Pyrococcushorikoshii) |
PF00162(PGK) | 5 | THR A 69ILE A 87THR A 13VAL A 140LEU A 137 | None | 1.00A | 3a51D-2cunA:undetectable | 3a51D-2cunA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2esp | UBIQUITIN-CONJUGATING ENZYME E2 D2 (Homo sapiens) |
PF00179(UQ_con) | 5 | ILE A 99LEU A 103ILE A 106PRO A 65LEU A 89 | None | 1.16A | 3a51D-2espA:undetectable | 3a51D-2espA:16.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2goj | FE-SUPEROXIDEDISMUTASE (Plasmodiumfalciparum) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 5 | ILE A 96MET A 195ILE A 153VAL A 182PRO A 88 | None | 1.10A | 3a51D-2gojA:undetectable | 3a51D-2gojA:15.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2icy | PROBABLEUTP-GLUCOSE-1-PHOSPHATEURIDYLYLTRANSFERASE2 (Arabidopsisthaliana) |
PF01704(UDPGP) | 5 | ILE A 434ASN A 383ILE A 413VAL A 424LEU A 422 | None | 1.11A | 3a51D-2icyA:undetectable | 3a51D-2icyA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iuj | LIPOXYGENASE L-5 (Glycine max) |
PF00305(Lipoxygenase)PF01477(PLAT) | 5 | THR A 570ILE A 718LEU A 762ILE A 765VAL A 345 | None | 1.25A | 3a51D-2iujA:undetectable | 3a51D-2iujA:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iy4 | NON-HEMEIRON-CONTAININGFERRITIN (Listeriamonocytogenes) |
PF00210(Ferritin) | 5 | MET A 46ILE A 27LYS A 93MET A 95VAL A 84 | None | 0.88A | 3a51D-2iy4A:undetectable | 3a51D-2iy4A:17.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2quq | CENTROMEREDNA-BINDING PROTEINCOMPLEX CBF3 SUBUNITB (Saccharomycescerevisiae) |
PF16846(Cep3) | 5 | MET A 174ILE A 171LEU A 179ILE A 182LEU A 106 | None | 1.02A | 3a51D-2quqA:2.1 | 3a51D-2quqA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xbt | CELLULOSOMALSCAFFOLDIN (Pseudobacteroidescellulosolvens) |
PF00942(CBM_3) | 5 | ILE A 113LEU A 93ILE A 45VAL A 146LEU A 12 | None | 0.95A | 3a51D-2xbtA:undetectable | 3a51D-2xbtA:16.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xgt | ASPARAGINYL-TRNASYNTHETASE,CYTOPLASMIC (Brugia malayi) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 5 | THR A 428LEU A 464ILE A 472VAL A 361PRO A 384 | None | 1.13A | 3a51D-2xgtA:undetectable | 3a51D-2xgtA:19.83 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xkr | PUTATIVE CYTOCHROMEP450 142 (Mycobacteriumtuberculosis) |
PF00067(p450) | 6 | MET A 74ILE A 76LEU A 226ILE A 229THR A 234VAL A 277 | PG4 A1399 ( 4.4A)HEM A1400 (-4.1A)HEM A1400 (-4.4A)PG4 A1399 ( 4.5A)HEM A1400 (-3.7A)HEM A1400 (-4.5A) | 0.64A | 3a51D-2xkrA:45.0 | 3a51D-2xkrA:35.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xr1 | CLEAVAGE ANDPOLYADENYLATIONSPECIFICITY FACTOR100 KD SUBUNIT (Methanosarcinamazei) |
PF07521(RMMBL)PF07650(KH_2)PF10996(Beta-Casp)PF16661(Lactamase_B_6)PF17214(KH_7) | 5 | THR A 60ILE A 51THR A 38VAL A 22LEU A 18 | None | 1.21A | 3a51D-2xr1A:undetectable | 3a51D-2xr1A:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zbm | PROTEIN-TYROSINE-PHOSPHATASE (Shewanella sp.) |
PF00149(Metallophos) | 5 | THR A 53ILE A 187ASN A 101ILE A 59LEU A 145 | None | 1.24A | 3a51D-2zbmA:undetectable | 3a51D-2zbmA:22.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2zbz | CYTOCHROME P450-SU1 (Streptomycesgriseolus) |
PF00067(p450) | 5 | ILE A 96ASN A 194LEU A 240ILE A 243THR A 248 | HEM A 413 (-4.0A)NoneHEM A 413 ( 4.5A)VDX A 501 (-4.2A)HEM A 413 (-3.2A) | 1.12A | 3a51D-2zbzA:47.7 | 3a51D-2zbzA:37.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aeh | HEMOGLOBIN-BINDINGPROTEASE HBPAUTOTRANSPORTER (Escherichiacoli) |
PF03797(Autotransporter) | 5 | THR A1166ILE A1096THR A1311VAL A1276LEU A1255 | None | 0.95A | 3a51D-3aehA:undetectable | 3a51D-3aehA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aiz | DNA POLYMERASESLIDING CLAMP C (Sulfurisphaeratokodaii) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | THR C 75ILE C 25LEU C 18ILE C 14LEU C 34 | None | 1.10A | 3a51D-3aizC:undetectable | 3a51D-3aizC:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c75 | METHYLAMINEDEHYDROGENASE HEAVYCHAIN (Paracoccusversutus) |
PF06433(Me-amine-dh_H) | 5 | THR H 359ILE H 333LEU H 355ILE H 363VAL H 377 | None | 1.15A | 3a51D-3c75H:undetectable | 3a51D-3c75H:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cuq | VACUOLAR-SORTINGPROTEIN SNF8 (Homo sapiens) |
PF04157(EAP30) | 5 | ILE A 105LEU A 151ILE A 148VAL A 128LEU A 124 | None | 1.16A | 3a51D-3cuqA:undetectable | 3a51D-3cuqA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d6k | PUTATIVEAMINOTRANSFERASE (Corynebacteriumdiphtheriae) |
PF12897(Aminotran_MocR) | 5 | ILE A 348LEU A 327ILE A 326PRO A 393LEU A 401 | None | 1.21A | 3a51D-3d6kA:undetectable | 3a51D-3d6kA:23.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eb0 | PUTATIVEUNCHARACTERIZEDPROTEIN (Cryptosporidiumparvum) |
PF00069(Pkinase) | 5 | ILE A 305MET A 140LEU A 301VAL A 154LEU A 150 | None | 1.22A | 3a51D-3eb0A:undetectable | 3a51D-3eb0A:22.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ejb | BIOTIN BIOSYNTHESISCYTOCHROME P450-LIKEENZYME (Bacillussubtilis) |
PF00067(p450) | 5 | MET B 79ASN B 181LEU B 230ILE B 233THR B 238 | NoneNoneHEM B 405 ( 4.6A)NoneHEM B 405 (-3.7A) | 0.85A | 3a51D-3ejbB:47.6 | 3a51D-3ejbB:36.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f8r | THIOREDOXINREDUCTASE (TRXB-3) (Sulfolobussolfataricus) |
PF07992(Pyr_redox_2) | 5 | THR A 289ILE A 121MET A 275ILE A 118VAL A 104 | NoneNAP A4005 (-3.8A)NoneNoneNone | 1.13A | 3a51D-3f8rA:undetectable | 3a51D-3f8rA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gff | IROE-LIKE SERINEHYDROLASE (Shewanellaoneidensis) |
PF00756(Esterase) | 5 | ILE A 80ASN A 135LEU A 124VAL A 149LEU A 140 | None | 1.17A | 3a51D-3gffA:undetectable | 3a51D-3gffA:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gg4 | GLYCEROL KINASE (Yersiniapseudotuberculosis) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | ASN A 395LEU A 146THR A 189VAL A 128LEU A 129 | None | 1.14A | 3a51D-3gg4A:undetectable | 3a51D-3gg4A:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h5o | TRANSCRIPTIONALREGULATOR GNTR (Chromobacteriumviolaceum) |
PF13377(Peripla_BP_3) | 5 | THR A 133MET A 155ILE A 305ASN A 107ILE A 92 | NoneNoneNoneSO4 A 1 (-3.2A)None | 1.14A | 3a51D-3h5oA:undetectable | 3a51D-3h5oA:25.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j23 | CAPSID PROTEIN VP3 (Enterovirus A) |
PF00073(Rhv) | 5 | THR C 153ILE C 133LEU C 167ILE C 169VAL C 55 | None | 1.22A | 3a51D-3j23C:undetectable | 3a51D-3j23C:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j26 | CAPSID PROTEIN V20 (Mimivirus-dependentvirus Sputnik) |
no annotation | 5 | ILE A 106LEU A 238ILE A 262VAL A 71LEU A 203 | None | 1.22A | 3a51D-3j26A:undetectable | 3a51D-3j26A:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ju1 | ENOYL-COAHYDRATASE/ISOMERASEFAMILY PROTEIN (Shewanellaoneidensis) |
PF16113(ECH_2) | 5 | MET A 190ILE A 153ASN A 173MET A 175VAL A 125 | None | 1.21A | 3a51D-3ju1A:undetectable | 3a51D-3ju1A:23.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k8p | DSL1 (Kluyveromyceslactis) |
PF11989(Dsl1_C) | 5 | THR C 633ILE C 600THR C 541VAL C 522LEU C 526 | None | 1.05A | 3a51D-3k8pC:undetectable | 3a51D-3k8pC:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mg6 | PROTEASOME COMPONENTC11 (Saccharomycescerevisiae) |
PF00227(Proteasome) | 5 | ILE J 59LEU J 37ILE J 101VAL J 97LEU J 87 | None | 1.23A | 3a51D-3mg6J:undetectable | 3a51D-3mg6J:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nic | ECO29KIR (Escherichiacoli) |
PF09517(RE_Eco29kI) | 5 | ILE A 105LEU A 101ILE A 129THR A 32PRO A 39 | None | 1.19A | 3a51D-3nicA:undetectable | 3a51D-3nicA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rrv | ENOYL-COAHYDRATASE/ISOMERASE (Mycobacteriumavium) |
PF00378(ECH_1) | 5 | ILE A 92LEU A 114THR A 151VAL A 223LEU A 227 | None | 1.13A | 3a51D-3rrvA:undetectable | 3a51D-3rrvA:24.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u7b | ENDO-1,4-BETA-XYLANASE (Fusariumoxysporum) |
PF00331(Glyco_hydro_10) | 5 | THR A 320ILE A 269LYS A 14LEU A 246LEU A 231 | None | 1.17A | 3a51D-3u7bA:undetectable | 3a51D-3u7bA:21.01 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3zby | P450 HEME-THIOLATEPROTEIN (Mycolicibacteriumsmegmatis) |
PF00067(p450) | 5 | ILE A 79LEU A 229ILE A 232THR A 237VAL A 280 | HEM A1402 (-4.2A)HEM A1402 ( 4.6A)NoneHEM A1402 (-3.7A)HEM A1402 (-4.4A) | 0.61A | 3a51D-3zbyA:42.8 | 3a51D-3zbyA:36.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zh2 | L-LACTATEDEHYDROGENASE (Plasmodiumfalciparum) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | ILE A 244ASN A 127ILE A 123VAL A 31LEU A 9 | None | 1.21A | 3a51D-3zh2A:undetectable | 3a51D-3zh2A:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zuq | BOTULINUM NEUROTOXINTYPE B (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07952(Toxin_trans) | 5 | ILE A 112ASN A 364LEU A 236ILE A 233THR A 172 | None | 1.23A | 3a51D-3zuqA:undetectable | 3a51D-3zuqA:16.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ad9 | BETA-LACTAMASE-LIKEPROTEIN 2 (Homo sapiens) |
PF00753(Lactamase_B) | 5 | ILE A 93ILE A 73THR A 33VAL A 18LEU A 35 | None | 1.21A | 3a51D-4ad9A:undetectable | 3a51D-4ad9A:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c90 | ALPHA-GLUCURONIDASEGH115 (Bacteroidesovatus) |
PF15979(Glyco_hydro_115) | 5 | MET A 477ILE A 473LEU A 239ILE A 236LEU A 204 | None | 0.99A | 3a51D-4c90A:undetectable | 3a51D-4c90A:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cyj | PAB-DEPENDENTPOLY(A)-SPECIFICRIBONUCLEASE SUBUNITPAN3-LIKE PROTEIN (Chaetomiumthermophilum) |
no annotation | 5 | LEU A 401ILE A 407THR A 369VAL A 365LEU A 445 | None | 1.18A | 3a51D-4cyjA:undetectable | 3a51D-4cyjA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fkz | UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE (Bacillussubtilis) |
PF02350(Epimerase_2) | 5 | ASN A 158THR A 282VAL A 298PRO A 292LEU A 316 | None | 1.17A | 3a51D-4fkzA:undetectable | 3a51D-4fkzA:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gxz | SUPPRESSION OFCOPPER SENSITIVITYPROTEIN (Salmonellaenterica) |
PF01323(DSBA) | 5 | ILE A 119LEU A 107THR A 92VAL A 131LEU A 133 | None | 1.18A | 3a51D-4gxzA:undetectable | 3a51D-4gxzA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h3w | HYPOTHETICAL PROTEIN (Parabacteroidesdistasonis) |
PF15414(DUF4621) | 5 | ILE A 121LEU A 195ILE A 99VAL A 186LEU A 221 | None | 1.20A | 3a51D-4h3wA:undetectable | 3a51D-4h3wA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l0c | DEFORMYLASE (Pseudomonasputida) |
PF12697(Abhydrolase_6) | 5 | LEU A 195ILE A 202THR A 230VAL A 206PRO A 119 | None | 1.14A | 3a51D-4l0cA:undetectable | 3a51D-4l0cA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mwt | LYSOSOMAL PROTECTIVEPROTEIN (Homo sapiens) |
PF00450(Peptidase_S10) | 5 | LEU A 387ILE A 419VAL A 176PRO A 157LEU A 174 | LEU A 387 ( 0.6A)ILE A 419 ( 0.6A)VAL A 176 ( 0.6A)PRO A 157 ( 1.1A)LEU A 174 ( 0.5A) | 1.09A | 3a51D-4mwtA:undetectable | 3a51D-4mwtA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4omb | PHOSPHATE BINDINGPROTEIN (Pseudomonasaeruginosa) |
PF12849(PBP_like_2) | 5 | THR A 139ILE A 146LEU A 165ILE A 135VAL A 218 | None | 1.19A | 3a51D-4ombA:undetectable | 3a51D-4ombA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ph9 | PROSTAGLANDIN G/HSYNTHASE 2 (Mus musculus) |
PF00008(EGF)PF03098(An_peroxidase) | 5 | ASN A 39ILE A 499THR A 483VAL A 510PRO A 506 | None | 1.10A | 3a51D-4ph9A:undetectable | 3a51D-4ph9A:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4plh | MALATE DEHYDROGENASE (Apicomplexa) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | ILE A 241ASN A 122ILE A 118VAL A 31LEU A 9 | NoneOXM A 401 ( 3.3A)NoneNoneNone | 1.23A | 3a51D-4plhA:undetectable | 3a51D-4plhA:24.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rwt | LEIOMODIN-2 (Homo sapiens) |
no annotation | 5 | THR C 218ILE C 248ASN C 185ILE C 228LEU C 269 | None | 0.75A | 3a51D-4rwtC:undetectable | 3a51D-4rwtC:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xkj | D-LACTATEDEHYDROGENASE (Sporolactobacillusinulinus) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | THR A 38ILE A 4ASN A 58ILE A 50VAL A 315 | None | 0.96A | 3a51D-4xkjA:undetectable | 3a51D-4xkjA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xri | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF03810(IBN_N)PF13513(HEAT_EZ) | 5 | ILE A 368ILE A 373VAL A 406PRO A 402LEU A 407 | None | 1.09A | 3a51D-4xriA:3.0 | 3a51D-4xriA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z79 | LEIOMODIN-1ACTIN-BINDING SITE 2(ABS2) (Homo sapiens) |
no annotation | 5 | THR A 369ILE A 399ASN A 336ILE A 379LEU A 420 | NoneNoneGOL A 505 (-4.2A)NoneNone | 0.84A | 3a51D-4z79A:undetectable | 3a51D-4z79A:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z8g | TROPOMODULIN-1,LEIOMODIN-1 CHIMERA(TP1 ABS2) (Homo sapiens) |
no annotation | 5 | THR A 369ILE A 399ASN A 201ILE A 379LEU A 420 | NoneNone NI A 509 (-4.0A)NoneNone | 0.81A | 3a51D-4z8gA:undetectable | 3a51D-4z8gA:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z94 | GELSOLIN,TROPOMODULIN-1,LEIOMODIN-1 CHIMERA (Homo sapiens) |
PF00626(Gelsolin) | 5 | THR G1369ILE G1399ASN G1201ILE G1379LEU G1420 | None | 0.86A | 3a51D-4z94G:undetectable | 3a51D-4z94G:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b83 | TETRA UBIQUITIN (Homo sapiens) |
PF00240(ubiquitin) | 5 | THR A 85ILE A 89ILE A 112VAL A 102LEU A 119 | None | 1.18A | 3a51D-5b83A:undetectable | 3a51D-5b83A:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b8i | SERINE/THREONINE-PROTEIN PHOSPHATASE (Coccidioidesimmitis) |
PF00149(Metallophos) | 5 | ILE A 216LEU A 214ILE A 208VAL A 105LEU A 132 | None | 1.24A | 3a51D-5b8iA:undetectable | 3a51D-5b8iA:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cxu | FERULIC ACIDESTERASE AMCE1/FAE1A (Anaeromycesmucronatus) |
PF00756(Esterase) | 5 | MET A 134ILE A 133ILE A 165PRO A 99LEU A 62 | None | 1.24A | 3a51D-5cxuA:undetectable | 3a51D-5cxuA:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ez7 | FLAVOENZYME PA4991 (Pseudomonasaeruginosa) |
PF01266(DAO) | 5 | ILE A 16LEU A 346ILE A 52VAL A 93LEU A 90 | FAD A 401 (-4.8A)FAD A 401 (-4.3A)NoneNoneNone | 1.07A | 3a51D-5ez7A:undetectable | 3a51D-5ez7A:25.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fai | RIBOSOMAL RNA SMALLSUBUNITMETHYLTRANSFERASENEP1 (Homo sapiens) |
PF03587(EMG1) | 5 | ILE A 118ASN A 65LEU A 140THR A 124LEU A 92 | NoneUNX A 304 ( 4.1A)NoneNoneNone | 1.02A | 3a51D-5faiA:undetectable | 3a51D-5faiA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fav | CHOLINETRIMETHYLAMINE-LYASE (Desulfovibrioalaskensis) |
PF01228(Gly_radical)PF02901(PFL-like) | 5 | ILE A 338ILE A 317VAL A 422PRO A 430LEU A 371 | None | 1.23A | 3a51D-5favA:2.9 | 3a51D-5favA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fo1 | RIBOFLAVINBIOSYNTHESIS PROTEINRIBF (Corynebacteriumammoniagenes) |
PF01687(Flavokinase)PF06574(FAD_syn) | 5 | THR A 208ILE A 252ASN A 241MET A 242LEU A 318 | None | 1.17A | 3a51D-5fo1A:undetectable | 3a51D-5fo1A:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g4q | DNA POLYMERASE IIISUBUNIT BETA (Helicobacterpylori) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | THR A 91MET A 1ILE A 3MET A 109LEU A 10 | None | 1.10A | 3a51D-5g4qA:undetectable | 3a51D-5g4qA:21.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 5 | ILE A 88ASN A 181MET A 184LEU A 232VAL A 283 | HEM A 501 ( 4.4A)NoneNoneHEM A 501 ( 4.7A)HEM A 501 (-4.7A) | 1.00A | 3a51D-5gnmA:56.7 | 3a51D-5gnmA:98.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 5 | ILE A 88MET A 184LEU A 232VAL A 283PRO A 287 | HEM A 501 ( 4.4A)NoneHEM A 501 ( 4.7A)HEM A 501 (-4.7A)HEM A 501 (-3.5A) | 0.94A | 3a51D-5gnmA:56.7 | 3a51D-5gnmA:98.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 7 | MET A 86ILE A 88ASN A 181LEU A 232ILE A 235THR A 240VAL A 283 | NoneHEM A 501 ( 4.4A)NoneHEM A 501 ( 4.7A)NoneHEM A 501 (-3.7A)HEM A 501 (-4.7A) | 1.28A | 3a51D-5gnmA:56.7 | 3a51D-5gnmA:98.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 7 | THR A 84MET A 86ILE A 88ILE A 235THR A 240PRO A 287LEU A 387 | NoneNoneHEM A 501 ( 4.4A)NoneHEM A 501 (-3.7A)HEM A 501 (-3.5A)None | 0.90A | 3a51D-5gnmA:56.7 | 3a51D-5gnmA:98.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 8 | THR A 84MET A 86ILE A 88LEU A 232ILE A 235THR A 240VAL A 283PRO A 287 | NoneNoneHEM A 501 ( 4.4A)HEM A 501 ( 4.7A)NoneHEM A 501 (-3.7A)HEM A 501 (-4.7A)HEM A 501 (-3.5A) | 0.61A | 3a51D-5gnmA:56.7 | 3a51D-5gnmA:98.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h3c | PROTEIN SUPPRESSOROF NPR1-1,CONSTITUTIVE 1 (Arabidopsisthaliana) |
PF01582(TIR) | 5 | ILE A 77LEU A 174ILE A 171VAL A 32LEU A 37 | None | 1.12A | 3a51D-5h3cA:undetectable | 3a51D-5h3cA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kzm | TRYPTOPHAN SYNTHASEALPHA CHAIN (Francisellatularensis) |
PF00290(Trp_syntA) | 5 | ASN A 69ILE A 37THR A 257VAL A 260PRO A 22 | None | 1.21A | 3a51D-5kzmA:undetectable | 3a51D-5kzmA:21.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5l1t | PENTALENOLACTONESYNTHASE (Streptomycesarenae) |
PF00067(p450) | 5 | ILE A 30ASN A 64ILE A 294THR A 51LEU A 309 | None | 1.20A | 3a51D-5l1tA:42.5 | 3a51D-5l1tA:34.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5l94 | CYTOCHROME P450 (Bacillusmegaterium) |
PF00067(p450) | 6 | ILE A 85LYS A 187LEU A 238ILE A 241THR A 246VAL A 289 | HEM A 501 (-4.4A)NoneHEM A 501 (-4.4A)TES A 502 (-4.0A)HEM A 501 (-3.4A)TES A 502 (-4.8A) | 0.45A | 3a51D-5l94A:49.7 | 3a51D-5l94A:34.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mz9 | - (-) |
no annotation | 5 | THR A 70ILE A 388ASN A 73ILE A 309LEU A 552 | None | 1.21A | 3a51D-5mz9A:undetectable | 3a51D-5mz9A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nug | CYTOPLASMIC DYNEIN 1HEAVY CHAIN 1 (Homo sapiens) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 5 | ILE A2534MET A2461LEU A2499ILE A2498THR A2522 | None | 1.12A | 3a51D-5nugA:undetectable | 3a51D-5nugA:6.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ti8 | AMINOTRANSFERASE (Pseudomonas sp.M1) |
PF00202(Aminotran_3) | 5 | ILE A 434LEU A 358ILE A 423VAL A 44LEU A 55 | None | 1.14A | 3a51D-5ti8A:undetectable | 3a51D-5ti8A:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ul4 | OXSB PROTEIN (Bacillusmegaterium) |
PF02310(B12-binding) | 5 | ILE A 213ASN A 137LEU A 197ILE A 196LEU A 173 | None | 1.16A | 3a51D-5ul4A:2.5 | 3a51D-5ul4A:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ulv | MALATE DEHYDROGENASE (Methylobacteriumextorquens) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | ILE A 240ASN A 121ILE A 117VAL A 30LEU A 8 | None | 1.24A | 3a51D-5ulvA:undetectable | 3a51D-5ulvA:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wlh | LBACAS13A H328A(C2C2) (LachnospiraceaebacteriumNK4A179) |
no annotation | 5 | ILE A 560LYS A 530ASN A 545LEU A 592LEU A 579 | None | 1.22A | 3a51D-5wlhA:1.1 | 3a51D-5wlhA:13.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xtb | NADH-UBIQUINONEOXIDOREDUCTASE 75KDA SUBUNIT,MITOCHONDRIAL (Homo sapiens) |
PF00384(Molybdopterin)PF09326(NADH_dhqG_C)PF10588(NADH-G_4Fe-4S_3)PF13510(Fer2_4) | 5 | ILE M 418ILE M 391VAL M 475PRO M 407LEU M 516 | None | 1.10A | 3a51D-5xtbM:undetectable | 3a51D-5xtbM:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xvm | STEROL3-BETA-GLUCOSYLTRANSFERASE (Saccharomycescerevisiae) |
PF00201(UDPGT)PF03033(Glyco_transf_28) | 5 | THR A 960ILE A1148ILE A1155VAL A 770LEU A 744 | None | 1.08A | 3a51D-5xvmA:undetectable | 3a51D-5xvmA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yj6 | DOCKERIN TYPE IREPEAT-CONTAININGPROTEIN (Ruminiclostridiumthermocellum) |
no annotation | 5 | LYS A 468ASN A 464ILE A 398PRO A 497LEU A 510 | None | 1.23A | 3a51D-5yj6A:undetectable | 3a51D-5yj6A:11.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ysm | CYTOCHROME P450 (Amycolatopsismediterranei) |
no annotation | 5 | ILE A 107LEU A 252ILE A 255THR A 260VAL A 303 | HEM A 501 (-4.2A)HEM A 501 ( 4.6A)NoneHEM A 501 (-3.7A)None | 0.74A | 3a51D-5ysmA:39.3 | 3a51D-5ysmA:12.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ep3 | - (-) |
no annotation | 5 | ILE A 20ASN A 65LEU A 54ILE A 51LEU A 36 | None | 1.18A | 3a51D-6ep3A:undetectable | 3a51D-6ep3A:undetectable |