SIMILAR PATTERNS OF AMINO ACIDS FOR 3A51_C_VDYC6178
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b44 | PROTEIN (B-POLSUBUNIT OFHEAT-LABILEENTEROTOXIN) (Escherichiacoli) |
PF01376(Enterotoxin_b)PF11590(DNAPolymera_Pol) | 5 | THR D 75ILE D 40LEU D 72MET D 101ILE D 20 | None | 1.09A | 3a51C-1b44D:0.0 | 3a51C-1b44D:13.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gff | BACTERIOPHAGE G4CAPSID PROTEINS GPF,GPG, GPJ (Escherichiavirus G4) |
PF02305(Phage_F) | 5 | THR 1 406MET 1 404ILE 1 49ASN 1 409ILE 1 66 | None | 1.07A | 3a51C-1gff1:0.0 | 3a51C-1gff1:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1io0 | TROPOMODULIN (Gallus gallus) |
no annotation | 5 | THR A 234ILE A 264ASN A 201VAL A 273LEU A 285 | None | 1.04A | 3a51C-1io0A:0.0 | 3a51C-1io0A:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ldj | CULLIN HOMOLOG 1 (Homo sapiens) |
PF00888(Cullin)PF10557(Cullin_Nedd8) | 5 | THR A 166ILE A 159LEU A 162VAL A 49LEU A 88 | None | 1.17A | 3a51C-1ldjA:2.3 | 3a51C-1ldjA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ldk | CULLIN HOMOLOG (Homo sapiens) |
PF00888(Cullin) | 5 | THR A 166ILE A 159LEU A 162VAL A 49LEU A 88 | None | 1.10A | 3a51C-1ldkA:0.6 | 3a51C-1ldkA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ltd | FLAVOCYTOCHROME B2 (Saccharomycescerevisiae) |
PF00173(Cyt-b5)PF01070(FMN_dh) | 5 | MET A 462ILE A 458LEU A 419THR A 221VAL A 223 | None | 1.15A | 3a51C-1ltdA:0.0 | 3a51C-1ltdA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mil | SHC ADAPTOR PROTEIN (Homo sapiens) |
PF00017(SH2) | 5 | ILE A 87LEU A 94ILE A 77VAL A 63LEU A 56 | None | 1.11A | 3a51C-1milA:undetectable | 3a51C-1milA:14.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mpx | ALPHA-AMINO ACIDESTER HYDROLASE (Xanthomonascitri) |
PF02129(Peptidase_S15)PF08530(PepX_C) | 5 | MET A 54ILE A 52ASN A 186VAL A 115LEU A 77 | NoneNoneGOL A3011 (-4.1A)NoneNone | 1.06A | 3a51C-1mpxA:0.0 | 3a51C-1mpxA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n7f | AMPA RECEPTORINTERACTING PROTEINGRIP (Rattusnorvegicus) |
PF00595(PDZ) | 5 | ILE A 684LEU A 701ILE A 750VAL A 746LEU A 675 | None | 1.00A | 3a51C-1n7fA:undetectable | 3a51C-1n7fA:11.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nrz | PTS SYSTEM,SORBOSE-SPECIFIC IIBCOMPONENT (Klebsiellapneumoniae) |
PF03830(PTSIIB_sorb) | 5 | MET A 108ILE A 9ILE A 154VAL A 139LEU A 134 | None | 1.16A | 3a51C-1nrzA:undetectable | 3a51C-1nrzA:16.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u1h | 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINEMETHYLTRANSFERASE (Arabidopsisthaliana) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 5 | THR A 71MET A 74ILE A 187LEU A 75THR A 232 | None | 1.17A | 3a51C-1u1hA:undetectable | 3a51C-1u1hA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ul1 | FLAP ENDONUCLEASE-1 (Homo sapiens) |
PF00752(XPG_N)PF00867(XPG_I) | 5 | ILE X 212LEU X 209ILE X 3VAL X 247LEU X 226 | None | 1.14A | 3a51C-1ul1X:undetectable | 3a51C-1ul1X:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z5x | ULTRASPIRACLEPROTEIN (USP) AHOMOLOGUE OF RXR (Bemisia tabaci) |
PF00104(Hormone_recep) | 5 | ILE U 315LEU U 314ILE U 482THR U 480LEU U 476 | NoneNonePO4 U 3 ( 4.8A)NoneNone | 1.17A | 3a51C-1z5xU:1.7 | 3a51C-1z5xU:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zfj | INOSINEMONOPHOSPHATEDEHYDROGENASE (Streptococcuspyogenes) |
PF00478(IMPDH)PF00571(CBS) | 5 | ILE A 48ASN A 282ILE A 346PRO A 47LEU A 356 | NoneIMP A 500 ( 4.5A)NoneNoneNone | 1.17A | 3a51C-1zfjA:undetectable | 3a51C-1zfjA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c9j | GREEN FLUORESCENTPROTEIN FP512 (Cerianthusmembranaceus) |
PF01353(GFP) | 5 | ILE A 75ILE A 192THR A 145PRO A 187LEU A 153 | None | 1.15A | 3a51C-2c9jA:undetectable | 3a51C-2c9jA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cun | PHOSPHOGLYCERATEKINASE (Pyrococcushorikoshii) |
PF00162(PGK) | 5 | THR A 69ILE A 87THR A 13VAL A 140LEU A 137 | None | 0.99A | 3a51C-2cunA:undetectable | 3a51C-2cunA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dc4 | 165AA LONGHYPOTHETICAL PROTEIN (Pyrococcushorikoshii) |
PF01928(CYTH) | 5 | ILE A 18LEU A 21ILE A 126VAL A 9LEU A 149 | None | 1.10A | 3a51C-2dc4A:undetectable | 3a51C-2dc4A:15.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iy4 | NON-HEMEIRON-CONTAININGFERRITIN (Listeriamonocytogenes) |
PF00210(Ferritin) | 5 | MET A 46ILE A 27LYS A 93MET A 95VAL A 84 | None | 1.05A | 3a51C-2iy4A:undetectable | 3a51C-2iy4A:17.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nvu | MALTOSE BINDINGPROTEIN/NEDD8-ACTIVATING ENZYME E1CATALYTIC SUBUNITCHIMERA (Homo sapiens) |
PF00899(ThiF)PF08825(E2_bind)PF13416(SBP_bac_8) | 5 | ILE B1109LEU B1263ILE B1060VAL B1024LEU B1021 | None | 1.05A | 3a51C-2nvuB:undetectable | 3a51C-2nvuB:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nyx | PROBABLETRANSCRIPTIONALREGULATORY PROTEIN,RV1404 (Mycobacteriumtuberculosis) |
PF01047(MarR) | 5 | THR A 76ILE A 53LEU A 69ILE A 89VAL A 113 | None | 1.17A | 3a51C-2nyxA:undetectable | 3a51C-2nyxA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p4z | METAL-DEPENDENTHYDROLASES OF THEBETA-LACTAMASESUPERFAMILY II (Caldanaerobactersubterraneus) |
PF00753(Lactamase_B) | 5 | THR A 161ILE A 239LEU A 228VAL A 248LEU A 222 | None | 1.20A | 3a51C-2p4zA:undetectable | 3a51C-2p4zA:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xgg | MICRONEME PROTEIN 2 (Toxoplasmagondii) |
PF00092(VWA) | 5 | MET A 186ILE A 184LEU A 214VAL A 113LEU A 106 | NoneGOL A1218 ( 4.7A)NoneNoneNone | 0.94A | 3a51C-2xggA:undetectable | 3a51C-2xggA:17.92 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xkr | PUTATIVE CYTOCHROMEP450 142 (Mycobacteriumtuberculosis) |
PF00067(p450) | 5 | MET A 74ILE A 76ILE A 229THR A 234VAL A 277 | PG4 A1399 ( 4.4A)HEM A1400 (-4.1A)PG4 A1399 ( 4.5A)HEM A1400 (-3.7A)HEM A1400 (-4.5A) | 0.71A | 3a51C-2xkrA:45.1 | 3a51C-2xkrA:35.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xmo | LMO2642 PROTEIN (Listeriamonocytogenes) |
PF00149(Metallophos) | 5 | ILE A 98LEU A 102THR A 126VAL A 88LEU A 85 | None | 1.18A | 3a51C-2xmoA:1.0 | 3a51C-2xmoA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xr1 | CLEAVAGE ANDPOLYADENYLATIONSPECIFICITY FACTOR100 KD SUBUNIT (Methanosarcinamazei) |
PF07521(RMMBL)PF07650(KH_2)PF10996(Beta-Casp)PF16661(Lactamase_B_6)PF17214(KH_7) | 5 | THR A 60ILE A 51THR A 38VAL A 22LEU A 18 | None | 1.19A | 3a51C-2xr1A:undetectable | 3a51C-2xr1A:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z7x | TOLL-LIKE RECEPTOR1, VARIABLELYMPHOCYTE RECEPTORB (Eptatretusburgeri;Homo sapiens) |
PF11921(DUF3439)PF13855(LRR_8) | 5 | LEU B 129ILE B 164THR B 212VAL B 210LEU B 192 | None | 1.18A | 3a51C-2z7xB:undetectable | 3a51C-2z7xB:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zl5 | 58 KD CAPSID PROTEIN (Norwalk virus) |
PF00915(Calici_coat)PF08435(Calici_coat_C) | 5 | ILE A 299LEU A 301ASN A 267ILE A 330THR A 341 | None | 1.14A | 3a51C-2zl5A:undetectable | 3a51C-2zl5A:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zvy | CHEMOTAXIS PROTEINMOTB (Salmonellaenterica) |
PF00691(OmpA) | 5 | ILE A 151LEU A 140MET A 161ILE A 261LEU A 226 | None | 1.20A | 3a51C-2zvyA:undetectable | 3a51C-2zvyA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aeh | HEMOGLOBIN-BINDINGPROTEASE HBPAUTOTRANSPORTER (Escherichiacoli) |
PF03797(Autotransporter) | 5 | THR A1166ILE A1096THR A1311VAL A1276LEU A1255 | None | 0.94A | 3a51C-3aehA:undetectable | 3a51C-3aehA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aiz | DNA POLYMERASESLIDING CLAMP B (Sulfurisphaeratokodaii) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | THR A 41LEU A 40ILE A 244VAL A 130PRO A 128 | None | 1.13A | 3a51C-3aizA:undetectable | 3a51C-3aizA:24.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bjo | UNCHARACTERIZEDATP-BINDING PROTEINMJ1010 (Methanocaldococcusjannaschii) |
no annotation | 5 | ILE A 75LEU A 76ILE A 44VAL A 99LEU A 100 | None | 1.12A | 3a51C-3bjoA:undetectable | 3a51C-3bjoA:12.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3csg | MALTOSE-BINDINGPROTEIN MONOBODY YS1FUSION (Escherichiacoli) |
PF00041(fn3)PF13416(SBP_bac_8) | 5 | ILE A 108LEU A 262ILE A 59VAL A 23LEU A 20 | None | 1.00A | 3a51C-3csgA:undetectable | 3a51C-3csgA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ctt | MALTASE-GLUCOAMYLASE (Homo sapiens) |
PF00088(Trefoil)PF01055(Glyco_hydro_31)PF16863(NtCtMGAM_N) | 5 | THR A 821ILE A 756LEU A 758ILE A 853VAL A 798 | None | 1.06A | 3a51C-3cttA:undetectable | 3a51C-3cttA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d4u | CARBOXYPEPTIDASE B2 (Bos taurus) |
PF00246(Peptidase_M14) | 5 | ILE A 189LEU A 183ASN A 144ILE A 64VAL A 304 | NoneNoneACT A 601 (-3.8A)NoneNone | 1.14A | 3a51C-3d4uA:undetectable | 3a51C-3d4uA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h5o | TRANSCRIPTIONALREGULATOR GNTR (Chromobacteriumviolaceum) |
PF13377(Peripla_BP_3) | 5 | THR A 133MET A 155ILE A 305ASN A 107ILE A 92 | NoneNoneNoneSO4 A 1 (-3.2A)None | 1.18A | 3a51C-3h5oA:undetectable | 3a51C-3h5oA:25.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hb0 | EYES ABSENT HOMOLOG2 (DROSOPHILA) (Homo sapiens) |
PF00702(Hydrolase) | 5 | ILE A 280LEU A 425ASN A 396THR A 449LEU A 445 | None | 1.08A | 3a51C-3hb0A:undetectable | 3a51C-3hb0A:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k8p | DSL1 (Kluyveromyceslactis) |
PF11989(Dsl1_C) | 5 | THR C 633ILE C 600THR C 541VAL C 522LEU C 526 | None | 1.02A | 3a51C-3k8pC:1.2 | 3a51C-3k8pC:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kdq | UNCHARACTERIZEDCONSERVED PROTEIN (Corynebacteriumdiphtheriae) |
no annotation | 5 | THR A 117MET A 118ILE A 123LEU A 100LEU A 92 | None | 1.16A | 3a51C-3kdqA:2.1 | 3a51C-3kdqA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kt9 | APRATAXIN (Homo sapiens) |
PF00498(FHA) | 5 | THR A 66MET A 89LEU A 87ILE A 27LEU A 19 | None | 1.19A | 3a51C-3kt9A:undetectable | 3a51C-3kt9A:13.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l2j | FUSION PROTEIN OFMALTOSE-BINDINGPERIPLASMIC PROTEINAND PARATHYROIDHORMONE/PARATHYROIDHORMONE-RELATEDPEPTIDE RECEPTOR (Escherichiacoli;Homo sapiens) |
PF02793(HRM)PF13416(SBP_bac_8) | 5 | ILE A-236LEU A -82ILE A-285VAL A-321LEU A-324 | None | 1.07A | 3a51C-3l2jA:undetectable | 3a51C-3l2jA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lpx | DNA GYRASE, ASUBUNIT (Colwelliapsychrerythraea) |
PF00521(DNA_topoisoIV) | 5 | THR A 324MET A 277ILE A 274LEU A 273ILE A 305 | None | 0.99A | 3a51C-3lpxA:1.7 | 3a51C-3lpxA:24.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mq9 | BONE MARROW STROMALANTIGEN 2 FUSED TOMALTOSE-BINDINGPERIPLASMIC PROTEIN (Escherichiacoli;Homo sapiens) |
PF13416(SBP_bac_8)PF16716(BST2) | 5 | ILE A 108LEU A 262ILE A 59VAL A 23LEU A 20 | None | 1.02A | 3a51C-3mq9A:undetectable | 3a51C-3mq9A:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mzk | PROTEIN TRANSPORTPROTEIN SEC16 (Saccharomycescerevisiae) |
PF12931(Sec16_C)PF12932(Sec16) | 5 | THR B1080ILE B1098LEU B1084VAL B1256LEU B1260 | None | 0.86A | 3a51C-3mzkB:undetectable | 3a51C-3mzkB:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3osl | CARBOXYPEPTIDASE B2 (Bos taurus) |
PF00246(Peptidase_M14) | 5 | ILE A 303LEU A 296ASN A 256ILE A 176VAL A 419 | None | 1.14A | 3a51C-3oslA:undetectable | 3a51C-3oslA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pj0 | LMO0305 PROTEIN (Listeriamonocytogenes) |
PF01212(Beta_elim_lyase) | 5 | ILE A 305LEU A 358ASN A 274ILE A 317LEU A 321 | None | 1.20A | 3a51C-3pj0A:undetectable | 3a51C-3pj0A:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sto | SERINE PROTEASEINHIBITOR (Schistosomahaematobium) |
PF00079(Serpin) | 5 | THR A 31LEU A 27ASN A 302ILE A 382PRO A 393 | None | 1.14A | 3a51C-3stoA:undetectable | 3a51C-3stoA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vov | GLUCOKINASE (Thermusthermophilus) |
PF00480(ROK) | 5 | ILE A 76LEU A 69THR A 31VAL A 39LEU A 43 | None | 1.15A | 3a51C-3vovA:undetectable | 3a51C-3vovA:23.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w1s | AUTOPHAGY PROTEIN 5 (Saccharomycescerevisiae) |
PF04106(APG5) | 5 | ILE A 37LEU A 35THR A 43VAL A 87LEU A 45 | None | 1.00A | 3a51C-3w1sA:undetectable | 3a51C-3w1sA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wai | MALTOSE-BINDINGPERIPLASMIC PROTEIN,TRANSMEMBRANEOLIGOSACCHARYLTRANSFERASE (Archaeoglobusfulgidus;Escherichiacoli) |
PF13416(SBP_bac_8) | 5 | ILE A 108LEU A 262ILE A 59VAL A 23LEU A 20 | None | 1.06A | 3a51C-3waiA:undetectable | 3a51C-3waiA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c60 | OCHRATOXINASE (Aspergillusniger) |
PF01979(Amidohydro_1) | 5 | ILE A 404LEU A 389VAL A 102PRO A 440LEU A 436 | None | 1.07A | 3a51C-4c60A:undetectable | 3a51C-4c60A:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dxb | MALTOSE-BINDINGPERIPLASMIC PROTEIN,BETA-LACTAMASE TEMCHIMERA (Escherichiacoli) |
PF01547(SBP_bac_1)PF13354(Beta-lactamase2) | 5 | ILE A 108LEU A 262ILE A 59VAL A 23LEU A 20 | None | 1.01A | 3a51C-4dxbA:undetectable | 3a51C-4dxbA:22.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g1p | CYS-GLYMETALLODIPEPTIDASEDUG1 (Saccharomycescerevisiae) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | ILE A 182LEU A 181THR A 435VAL A 196LEU A 98 | None | 1.17A | 3a51C-4g1pA:undetectable | 3a51C-4g1pA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gou | EHRGS-RHOGEF (Entamoebahistolytica) |
PF00615(RGS)PF00621(RhoGEF) | 5 | MET A 216ILE A 221LEU A 222ASN A 281ILE A 306 | None | 1.16A | 3a51C-4gouA:2.1 | 3a51C-4gouA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hnn | DIHYDRODIPICOLINATESYNTHASE (Vitis vinifera) |
PF00701(DHDPS) | 5 | LEU A 257MET A 234ILE A 302VAL A 313LEU A 273 | None | 1.12A | 3a51C-4hnnA:undetectable | 3a51C-4hnnA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ii3 | UBIQUITIN-60SRIBOSOMAL PROTEINL40 (Schizosaccharomycespombe) |
PF00240(ubiquitin) | 5 | THR B 9ILE B 13ILE B 36VAL B 26LEU B 43 | None | 1.13A | 3a51C-4ii3B:undetectable | 3a51C-4ii3B:14.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ikm | MALTOSE-BINDINGPERIPLASMIC PROTEIN,CASPASE RECRUITMENTDOMAIN-CONTAININGPROTEIN 8 (Escherichiacoli;Homo sapiens) |
PF00619(CARD)PF13416(SBP_bac_8) | 5 | ILE A 109LEU A 263ILE A 60VAL A 24LEU A 21 | None | 1.07A | 3a51C-4ikmA:undetectable | 3a51C-4ikmA:24.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4keg | MALTOSE-BINDINGPERIPLASMIC/PALATELUNG AND NASALEPITHELIUM CLONEFUSION PROTEIN (Escherichiacoli;Homo sapiens) |
PF01273(LBP_BPI_CETP)PF13416(SBP_bac_8) | 5 | ILE A 108LEU A 262ILE A 59VAL A 23LEU A 20 | NoneNoneNoneBOG A1301 ( 4.1A)None | 1.01A | 3a51C-4kegA:undetectable | 3a51C-4kegA:23.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l1g | PEPTIDOGLYCANN-ACETYLGLUCOSAMINEDEACETYLASE (Bacillus cereus) |
PF01522(Polysacc_deac_1) | 5 | LEU A 107ILE A 150VAL A 141PRO A 136LEU A 138 | NoneNoneNonePXU A 171 ( 4.9A)None | 1.01A | 3a51C-4l1gA:undetectable | 3a51C-4l1gA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l4w | ESPG3 (Mycolicibacteriumsmegmatis) |
PF14011(ESX-1_EspG) | 5 | ILE A 72LEU A 20ASN A 59VAL A 115LEU A 8 | None | 1.07A | 3a51C-4l4wA:undetectable | 3a51C-4l4wA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4log | MALTOSE ABCTRANSPORTERPERIPLASMIC PROTEINAND NR2E3 PROTEINCHIMERIC CONSTRUCT (Escherichiacoli;Homo sapiens) |
PF00104(Hormone_recep)PF13416(SBP_bac_8) | 5 | ILE A 110LEU A 264ILE A 61VAL A 25LEU A 22 | None | 0.93A | 3a51C-4logA:1.9 | 3a51C-4logA:23.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o2x | MALTOSE-BINDINGPERIPLASMIC PROTEIN,ATP-DEPENDENT CLPPROTEASE ADAPTORPROTEIN CLPSCONTAINING PROTEINCHIMERIC CONSTRUCT (Escherichiacoli;Plasmodiumfalciparum) |
PF02617(ClpS)PF13416(SBP_bac_8) | 5 | ILE A 109LEU A 263ILE A 60VAL A 24LEU A 21 | None | 1.04A | 3a51C-4o2xA:undetectable | 3a51C-4o2xA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ofs | PROBABLE LIPOAMIDEACYLTRANSFERASE (Thermoplasmaacidophilum) |
PF00198(2-oxoacid_dh) | 5 | MET A 43ILE A 46LEU A 47ASN A 152ILE A 66 | None | 1.13A | 3a51C-4ofsA:undetectable | 3a51C-4ofsA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ph9 | PROSTAGLANDIN G/HSYNTHASE 2 (Mus musculus) |
PF00008(EGF)PF03098(An_peroxidase) | 5 | ASN A 39ILE A 499THR A 483VAL A 510PRO A 506 | None | 1.11A | 3a51C-4ph9A:undetectable | 3a51C-4ph9A:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r0y | MALTOSE-BINDINGPERIPLASMIC PROTEIN,DISKSLARGE-ASSOCIATEDPROTEIN 1 (Escherichiacoli;Rattusnorvegicus) |
PF03359(GKAP)PF13416(SBP_bac_8) | 5 | ILE A 108LEU A 262ILE A 59VAL A 23LEU A 20 | None | 1.01A | 3a51C-4r0yA:undetectable | 3a51C-4r0yA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rwt | LEIOMODIN-2 (Homo sapiens) |
no annotation | 5 | THR C 218ILE C 248ASN C 185ILE C 228LEU C 269 | None | 0.86A | 3a51C-4rwtC:undetectable | 3a51C-4rwtC:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wrn | MALTOSE-BINDINGPERIPLASMICPROTEIN,UROMODULIN (Escherichiacoli;Homo sapiens) |
PF00100(Zona_pellucida)PF13416(SBP_bac_8) | 5 | ILE A 132LEU A 286ILE A 83VAL A 47LEU A 44 | None | 1.02A | 3a51C-4wrnA:undetectable | 3a51C-4wrnA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xd0 | TDP-3-AMINOQUINOVOSE-N-FORMYLTRANSFERASE (Providenciaalcalifaciens) |
PF00551(Formyl_trans_N)PF12796(Ank_2) | 5 | ILE A 5LEU A 28ILE A 70VAL A 163LEU A 167 | None | 1.11A | 3a51C-4xd0A:undetectable | 3a51C-4xd0A:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xkj | D-LACTATEDEHYDROGENASE (Sporolactobacillusinulinus) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | THR A 38ILE A 4ASN A 58ILE A 50VAL A 315 | None | 1.02A | 3a51C-4xkjA:undetectable | 3a51C-4xkjA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xri | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF03810(IBN_N)PF13513(HEAT_EZ) | 5 | ILE A 368ILE A 373VAL A 406PRO A 402LEU A 407 | None | 1.08A | 3a51C-4xriA:undetectable | 3a51C-4xriA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z79 | LEIOMODIN-1ACTIN-BINDING SITE 2(ABS2) (Homo sapiens) |
no annotation | 5 | THR A 369ILE A 399ASN A 336ILE A 379LEU A 420 | NoneNoneGOL A 505 (-4.2A)NoneNone | 0.81A | 3a51C-4z79A:undetectable | 3a51C-4z79A:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z8g | TROPOMODULIN-1,LEIOMODIN-1 CHIMERA(TP1 ABS2) (Homo sapiens) |
no annotation | 5 | THR A 369ILE A 399ASN A 201ILE A 379LEU A 420 | NoneNone NI A 509 (-4.0A)NoneNone | 0.79A | 3a51C-4z8gA:undetectable | 3a51C-4z8gA:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z94 | GELSOLIN,TROPOMODULIN-1,LEIOMODIN-1 CHIMERA (Homo sapiens) |
PF00626(Gelsolin) | 5 | THR G1369ILE G1399ASN G1201ILE G1379LEU G1420 | None | 0.84A | 3a51C-4z94G:undetectable | 3a51C-4z94G:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5auo | ATPASE INVOLVED INCHROMOSOMEPARTITIONING,PARA/MIND FAMILY,MRP HOMOLOG (Thermococcuskodakarensis) |
PF10609(ParA) | 5 | MET B 133ILE B 131LEU B 56VAL B 18LEU B 15 | None | 1.09A | 3a51C-5auoB:undetectable | 3a51C-5auoB:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b16 | RIBONUCLEASE3,DROSHA,RIBONUCLEASE3,DROSHA,RIBONUCLEASE 3 (Homo sapiens) |
PF00035(dsrm)PF00636(Ribonuclease_3)PF14622(Ribonucleas_3_3) | 5 | THR A 416ILE A 702THR A 590VAL A 856PRO A 683 | None | 1.06A | 3a51C-5b16A:undetectable | 3a51C-5b16A:15.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b83 | TETRA UBIQUITIN (Homo sapiens) |
PF00240(ubiquitin) | 5 | THR A 85ILE A 89ILE A 112VAL A 102LEU A 119 | None | 1.17A | 3a51C-5b83A:undetectable | 3a51C-5b83A:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dfm | MALTOSE-BINDINGPERIPLASMICPROTEIN,TELOMERASE-ASSOCIATED PROTEIN 19 (Escherichiacoli;Tetrahymenathermophila) |
PF13416(SBP_bac_8) | 5 | ILE A 108LEU A 262ILE A 59VAL A 23LEU A 20 | None | 1.06A | 3a51C-5dfmA:undetectable | 3a51C-5dfmA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dis | MALTOSE-BINDINGPERIPLASMICPROTEIN,NUCLEAR PORECOMPLEX PROTEINNUP214 (Escherichiacoli;Homo sapiens) |
PF13416(SBP_bac_8) | 5 | ILE D 108LEU D 262ILE D 59VAL D 23LEU D 20 | None | 1.11A | 3a51C-5disD:undetectable | 3a51C-5disD:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5doo | PROTEIN LYSINEMETHYLTRANSFERASE 2 (Rickettsiatyphi) |
PF10119(MethyTransf_Reg)PF13847(Methyltransf_31) | 5 | THR A 353MET A 358ILE A 361LEU A 362LEU A 411 | None | 1.12A | 3a51C-5dooA:undetectable | 3a51C-5dooA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e7p | CELL DIVISIONCONTROL PROTEINCDC48 (Mycolicibacteriumsmegmatis) |
PF00004(AAA)PF02359(CDC48_N) | 5 | ILE A 325LEU A 323ILE A 348VAL A 373LEU A 377 | None | 1.20A | 3a51C-5e7pA:undetectable | 3a51C-5e7pA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5es9 | LINEAR GRAMICIDINSYNTHETASE SUBUNIT A (Brevibacillusparabrevis) |
PF00501(AMP-binding)PF00550(PP-binding)PF00551(Formyl_trans_N)PF13193(AMP-binding_C) | 5 | MET A 654ILE A 600LEU A 650PRO A 602LEU A 581 | None | 1.19A | 3a51C-5es9A:undetectable | 3a51C-5es9A:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fsg | MALTOSE-BINDINGPERIPLASMIC PROTEIN,HANTAVIRUSNUCLEOPROTEIN (Hantaanorthohantavirus) |
PF00846(Hanta_nucleocap)PF13416(SBP_bac_8) | 5 | ILE A-264LEU A-110ILE A-313VAL A-349LEU A-352 | None | 0.98A | 3a51C-5fsgA:undetectable | 3a51C-5fsgA:22.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 7 | ILE A 88LEU A 89ILE A 235THR A 240VAL A 283PRO A 287LEU A 387 | HEM A 501 ( 4.4A)NoneNoneHEM A 501 (-3.7A)HEM A 501 (-4.7A)HEM A 501 (-3.5A)None | 0.81A | 3a51C-5gnmA:56.6 | 3a51C-5gnmA:98.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 8 | THR A 84MET A 86ILE A 88LEU A 89ILE A 235THR A 240VAL A 283PRO A 287 | NoneNoneHEM A 501 ( 4.4A)NoneNoneHEM A 501 (-3.7A)HEM A 501 (-4.7A)HEM A 501 (-3.5A) | 0.59A | 3a51C-5gnmA:56.6 | 3a51C-5gnmA:98.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gpp | MALTOSE-BINDINGPERIPLASMICPROTEIN,APOPTOSIS-ASSOCIATED SPECK-LIKEPROTEIN CONTAINING ACARD (Danio rerio;Escherichiacoli) |
PF02758(PYRIN)PF13416(SBP_bac_8) | 5 | ILE A 109LEU A 263ILE A 60VAL A 24LEU A 21 | None | 1.08A | 3a51C-5gppA:undetectable | 3a51C-5gppA:24.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gxv | MALTOSE-BINDINGPERIPLASMICPROTEIN,PIGG (Escherichiacoli;Serratia) |
PF13416(SBP_bac_8) | 5 | ILE A 110LEU A 264ILE A 61VAL A 25LEU A 22 | None | 0.99A | 3a51C-5gxvA:undetectable | 3a51C-5gxvA:24.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hss | LINALOOLDEHYDRATASE/ISOMERASE (Castellanielladefragrans) |
no annotation | 5 | THR A 202ILE A 209LEU A 206THR A 240LEU A 245 | None | 1.16A | 3a51C-5hssA:undetectable | 3a51C-5hssA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ii5 | MALTOSE-BINDINGPERIPLASMICPROTEIN,VITELLINEENVELOPE SPERM LYSINRECEPTOR (Escherichiacoli;Haliotisrufescens) |
PF11386(VERL)PF13416(SBP_bac_8) | 5 | ILE A3775LEU A3929ILE A3726VAL A3690LEU A3687 | None | 1.05A | 3a51C-5ii5A:undetectable | 3a51C-5ii5A:24.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jqe | SUGAR ABCTRANSPORTERSUBSTRATE-BINDINGPROTEIN,CASPASE-8CHIMERA (Escherichiacoli) |
PF01335(DED)PF13416(SBP_bac_8) | 5 | ILE A 120LEU A 274ILE A 71VAL A 35LEU A 32 | None | 1.06A | 3a51C-5jqeA:undetectable | 3a51C-5jqeA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k94 | MALTOSE-BINDINGPERIPLASMICPROTEIN,PROTEINTRANSLOCASE SUBUNITSECA,MALTOSE-BINDINGPERIPLASMIC PROTEIN (Escherichiacoli) |
PF01043(SecA_PP_bind)PF01547(SBP_bac_1)PF13416(SBP_bac_8) | 5 | ILE A 108LEU A1262ILE A 59VAL A 23LEU A 20 | None | 1.03A | 3a51C-5k94A:undetectable | 3a51C-5k94A:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kzm | TRYPTOPHAN SYNTHASEALPHA CHAIN (Francisellatularensis) |
PF00290(Trp_syntA) | 5 | ASN A 69ILE A 37THR A 257VAL A 260PRO A 22 | None | 1.18A | 3a51C-5kzmA:undetectable | 3a51C-5kzmA:21.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5l94 | CYTOCHROME P450 (Bacillusmegaterium) |
PF00067(p450) | 5 | ILE A 85LYS A 187ILE A 241THR A 246VAL A 289 | HEM A 501 (-4.4A)NoneTES A 502 (-4.0A)HEM A 501 (-3.4A)TES A 502 (-4.8A) | 0.36A | 3a51C-5l94A:49.9 | 3a51C-5l94A:34.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ny0 | L. REUTERIS SRRPBINDING REGION (Lactobacillusreuteri) |
no annotation | 5 | ILE A 294LEU A 290ILE A 282VAL A 331LEU A 333 | None | 1.12A | 3a51C-5ny0A:undetectable | 3a51C-5ny0A:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o6y | PEPTIDOGLYCANN-ACETYLGLUCOSAMINEDEACETYLASE (Bacillus cereus) |
no annotation | 5 | LEU B 107ILE B 150VAL B 141PRO B 136LEU B 138 | NoneNoneNone NA B 311 ( 4.6A)PXU B 171 ( 4.9A) | 1.04A | 3a51C-5o6yB:undetectable | 3a51C-5o6yB:10.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vaw | MALTOSE-BINDINGPERIPLASMICPROTEIN,TYPE IVPILIN PILA (Acinetobacterbaumannii;Escherichiacoli) |
no annotation | 5 | ILE A 108LEU A 262ILE A 59VAL A 23LEU A 20 | NoneSER A1205 (-3.9A)NoneNoneNone | 0.97A | 3a51C-5vawA:undetectable | 3a51C-5vawA:11.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wvm | MALTOSE-BINDINGPERIPLASMICPROTEIN,TWO-COMPONENT SYSTEM SENSORKINASE (Escherichiacoli;Serratiamarcescens) |
no annotation | 5 | ILE A 110LEU A 264ILE A 61VAL A 25LEU A 22 | None | 1.03A | 3a51C-5wvmA:2.7 | 3a51C-5wvmA:11.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wxv | ISOCHORISMATE LYASE (Vibrioanguillarum) |
no annotation | 5 | THR A 79ILE A 147LEU A 36LYS A 129VAL A 196 | None | 1.16A | 3a51C-5wxvA:undetectable | 3a51C-5wxvA:12.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xtb | NADH-UBIQUINONEOXIDOREDUCTASE 75KDA SUBUNIT,MITOCHONDRIAL (Homo sapiens) |
PF00384(Molybdopterin)PF09326(NADH_dhqG_C)PF10588(NADH-G_4Fe-4S_3)PF13510(Fer2_4) | 5 | ILE M 418ILE M 391VAL M 475PRO M 407LEU M 516 | None | 1.12A | 3a51C-5xtbM:undetectable | 3a51C-5xtbM:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xvm | STEROL3-BETA-GLUCOSYLTRANSFERASE (Saccharomycescerevisiae) |
PF00201(UDPGT)PF03033(Glyco_transf_28) | 5 | THR A 960ILE A1148ILE A1155VAL A 770LEU A 744 | None | 1.11A | 3a51C-5xvmA:undetectable | 3a51C-5xvmA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6apx | MALTOSE-BINDINGPERIPLASMICPROTEIN,DUALSPECIFICITY PROTEINPHOSPHATASE 1 (Escherichiacoli;Homo sapiens) |
no annotation | 5 | ILE A 108LEU A 262ILE A 59VAL A 23LEU A 20 | None | 1.08A | 3a51C-6apxA:undetectable | 3a51C-6apxA:24.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c33 | 5'-3' EXONUCLEASE (Mycolicibacteriumsmegmatis) |
no annotation | 5 | ILE A 114LEU A 55MET A 13ILE A 105VAL A 294 | None | 1.18A | 3a51C-6c33A:undetectable | 3a51C-6c33A:10.67 |