SIMILAR PATTERNS OF AMINO ACIDS FOR 3A50_D_VD3D2001
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cli | PROTEIN(PHOSPHORIBOSYL-AMINOIMIDAZOLESYNTHETASE) (Escherichiacoli) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | ILE A 26LEU A 22ILE A 126ALA A 127THR A 33 | None | 1.09A | 3a50D-1cliA:undetectable | 3a50D-1cliA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e4o | MALTODEXTRINPHOSPHORYLASE (Escherichiacoli) |
PF00343(Phosphorylase) | 5 | MET A 726ILE A 730LEU A 727LEU A 549LEU A 703 | None | 1.02A | 3a50D-1e4oA:0.0 | 3a50D-1e4oA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gnw | GLUTATHIONES-TRANSFERASE (Arabidopsisthaliana) |
PF00043(GST_C)PF02798(GST_N) | 5 | PRO A 55LEU A 21ILE A 74ALA A 75LEU A 170 | GTX A 212 (-4.6A)NoneNoneNoneNone | 1.10A | 3a50D-1gnwA:2.6 | 3a50D-1gnwA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h81 | POLYAMINE OXIDASE (Zea mays) |
PF01593(Amino_oxidase) | 5 | LEU A 212LEU A 445ASN A 70ILE A 448ALA A 451 | None | 1.07A | 3a50D-1h81A:undetectable | 3a50D-1h81A:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pgj | 6-PHOSPHOGLUCONATEDEHYDROGENASE (Trypanosomabrucei) |
PF00393(6PGD)PF03446(NAD_binding_2) | 5 | ILE A 195MET A 382ILE A 338ALA A 336LEU A 229 | None | 1.14A | 3a50D-1pgjA:0.0 | 3a50D-1pgjA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qgd | PROTEIN(TRANSKETOLASE) (Escherichiacoli) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | PRO A 238ILE A 120LEU A 169ILE A 417ALA A 416 | None | 1.12A | 3a50D-1qgdA:undetectable | 3a50D-1qgdA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r44 | D-ALANYL-D-ALANINEDIPEPTIDASE (Enterococcusfaecium) |
PF01427(Peptidase_M15) | 5 | MET A 170LEU A 166LEU A 66ILE A 122ALA A 121 | None | 1.02A | 3a50D-1r44A:undetectable | 3a50D-1r44A:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rrm | LACTALDEHYDEREDUCTASE (Escherichiacoli) |
PF00465(Fe-ADH) | 5 | ILE A 202LEU A 285LEU A 229ILE A 225ALA A 221 | None | 1.00A | 3a50D-1rrmA:undetectable | 3a50D-1rrmA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sh2 | RNA POLYMERASE (Norwalk virus) |
PF00680(RdRP_1) | 5 | ILE A 215LEU A 213ILE A 261ALA A 258LEU A 202 | None | 1.07A | 3a50D-1sh2A:0.0 | 3a50D-1sh2A:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vb3 | THREONINE SYNTHASE (Escherichiacoli) |
PF00291(PALP)PF14821(Thr_synth_N) | 5 | PRO A 36MET A 1ILE A 63LEU A 219ILE A 216 | None | 1.01A | 3a50D-1vb3A:undetectable | 3a50D-1vb3A:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vi4 | REGULATOR OFRIBONUCLEASEACTIVITY A PROTEIN 1 (Vibrio cholerae) |
PF03737(RraA-like) | 5 | MET A 154ILE A 152LEU A 145LEU A 132ASN A 129 | None | 1.13A | 3a50D-1vi4A:undetectable | 3a50D-1vi4A:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xzq | PROBABLE TRNAMODIFICATION GTPASETRME (Thermotogamaritima) |
PF01926(MMR_HSR1)PF10396(TrmE_N)PF12631(MnmE_helical) | 5 | ILE A 367LEU A 296LEU A 232ILE A 254LEU A 360 | None | 1.08A | 3a50D-1xzqA:undetectable | 3a50D-1xzqA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zkl | HIGH-AFFINITYCAMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE 7A (Homo sapiens) |
PF00233(PDEase_I) | 5 | LEU A 189LEU A 244MET A 310ILE A 247THR A 221 | None | 1.05A | 3a50D-1zklA:undetectable | 3a50D-1zklA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b39 | C3 (Bos taurus) |
PF00207(A2M)PF01759(NTR)PF01821(ANATO)PF01835(A2M_N)PF07677(A2M_recep)PF07678(A2M_comp)PF07703(A2M_N_2)PF10569(Thiol-ester_cl) | 6 | PRO A 700ILE A1428LEU A1420LEU A1385ILE A1387LEU A1442 | None | 1.42A | 3a50D-2b39A:undetectable | 3a50D-2b39A:12.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cdq | ASPARTOKINASE (Arabidopsisthaliana) |
PF00696(AA_kinase) | 5 | ILE A 129LEU A 135ILE A 91ALA A 88LEU A 122 | None | 1.10A | 3a50D-2cdqA:undetectable | 3a50D-2cdqA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fgy | CARBOXYSOME SHELLPOLYPEPTIDE (Halothiobacillusneapolitanus) |
PF08936(CsoSCA) | 5 | PRO A 307ILE A 238LEU A 291LEU A 372ILE A 302 | None | 1.10A | 3a50D-2fgyA:undetectable | 3a50D-2fgyA:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ivg | CYANATE LYASE (Escherichiacoli) |
PF02560(Cyanate_lyase) | 5 | LEU A 48ILE A 32ALA A 33THR A 36LEU A 53 | None | 1.09A | 3a50D-2ivgA:undetectable | 3a50D-2ivgA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2le0 | POLY [ADP-RIBOSE]POLYMERASE 1 (Rattusnorvegicus) |
PF00533(BRCT) | 5 | PRO A 3MET A 7ILE A 9LEU A 4LEU A 87 | None | 1.07A | 3a50D-2le0A:undetectable | 3a50D-2le0A:14.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pkg | SERINE/THREONINE-PROTEIN PHOSPHATASE 2A65 KDA REGULATORYSUBUNIT A ALPHAISOFORM (Homo sapiens) |
PF02985(HEAT)PF13646(HEAT_2) | 5 | ASN A 22ILE A 38ALA A 39THR A 47LEU A 55 | None | 1.09A | 3a50D-2pkgA:undetectable | 3a50D-2pkgA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uvf | EXOPOLYGALACTURONASE (Yersiniaenterocolitica) |
PF00295(Glyco_hydro_28)PF12708(Pectate_lyase_3) | 5 | ILE A 191LEU A 211LEU A 203ILE A 180ALA A 179 | None | 1.08A | 3a50D-2uvfA:undetectable | 3a50D-2uvfA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vhl | N-ACETYLGLUCOSAMINE-6-PHOSPHATEDEACETYLASE (Bacillussubtilis) |
PF01979(Amidohydro_1) | 5 | PRO A 39LEU A 6ILE A 31ALA A 366LEU A 55 | None | 1.07A | 3a50D-2vhlA:undetectable | 3a50D-2vhlA:24.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vx4 | CELLVIBRIO JAPONICUSMANNANASE CJMAN26C (Cellvibriojaponicus) |
PF02156(Glyco_hydro_26) | 5 | PRO A 265ILE A 291LEU A 320ILE A 367ALA A 368 | None | 1.12A | 3a50D-2vx4A:undetectable | 3a50D-2vx4A:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vxy | CELL DIVISIONPROTEIN FTSZ (Bacillussubtilis) |
PF00091(Tubulin)PF12327(FtsZ_C) | 5 | PRO A 165MET A 226ILE A 228LEU A 249LEU A 190 | None | 1.13A | 3a50D-2vxyA:undetectable | 3a50D-2vxyA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2whk | MANNANENDO-1,4-BETA-MANNOSIDASE (Bacillussubtilis) |
PF02156(Glyco_hydro_26) | 5 | PRO A 159ILE A 63ILE A 236ALA A 263THR A 292 | None | 1.13A | 3a50D-2whkA:undetectable | 3a50D-2whkA:24.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xkr | PUTATIVE CYTOCHROMEP450 142 (Mycobacteriumtuberculosis) |
PF00067(p450) | 5 | MET A 74ILE A 76LEU A 159ILE A 229THR A 234 | PG4 A1399 ( 4.4A)HEM A1400 (-4.1A)NonePG4 A1399 ( 4.5A)HEM A1400 (-3.7A) | 0.86A | 3a50D-2xkrA:45.0 | 3a50D-2xkrA:35.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y4o | PHENYLACETATE-COENZYME A LIGASE (Burkholderiacenocepacia) |
PF00501(AMP-binding)PF14535(AMP-binding_C_2) | 5 | PRO A 182ILE A 235LEU A 211LEU A 186ILE A 215 | None | 1.08A | 3a50D-2y4oA:undetectable | 3a50D-2y4oA:23.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yn7 | OUTER SURFACEPROTEIN (Borreliellaburgdorferi) |
PF05714(Borrelia_lipo_1) | 5 | MET A 285ILE A 284LEU A 288LEU A 393ALA A 365 | None | 1.04A | 3a50D-2yn7A:undetectable | 3a50D-2yn7A:16.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z00 | DIHYDROOROTASE (Thermusthermophilus) |
PF01979(Amidohydro_1) | 5 | ILE A 2LEU A 3ILE A 28ALA A 376LEU A 47 | None | 0.95A | 3a50D-2z00A:undetectable | 3a50D-2z00A:24.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2zbz | CYTOCHROME P450-SU1 (Streptomycesgriseolus) |
PF00067(p450) | 6 | ILE A 96LEU A 180ASN A 194ILE A 243ALA A 244THR A 248 | HEM A 413 (-4.0A)VDX A 501 (-4.2A)NoneVDX A 501 (-4.2A)HEM A 413 (-3.5A)HEM A 413 (-3.2A) | 1.43A | 3a50D-2zbzA:47.7 | 3a50D-2zbzA:37.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zl5 | 58 KD CAPSID PROTEIN (Norwalk virus) |
PF00915(Calici_coat)PF08435(Calici_coat_C) | 6 | PRO A 317ILE A 299LEU A 301ASN A 267ILE A 330THR A 341 | None | 1.40A | 3a50D-2zl5A:undetectable | 3a50D-2zl5A:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zm2 | 6-AMINOHEXANOATE-DIMER HYDROLASE (Flavobacteriumsp.) |
PF00144(Beta-lactamase) | 5 | ILE A 66LEU A 73LEU A 382ILE A 360THR A 356 | None | 1.09A | 3a50D-2zm2A:undetectable | 3a50D-2zm2A:24.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3can | PYRUVATE-FORMATELYASE-ACTIVATINGENZYME (Bacteroidesvulgatus) |
PF04055(Radical_SAM) | 5 | ILE A 173ASN A 81ILE A 132ALA A 181LEU A 104 | None | 1.11A | 3a50D-3canA:undetectable | 3a50D-3canA:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cjp | PREDICTEDAMIDOHYDROLASE,DIHYDROOROTASEFAMILY (Clostridiumacetobutylicum) |
PF04909(Amidohydro_2) | 5 | PRO A 124ILE A 160LEU A 155LEU A 166LEU A 198 | None | 1.04A | 3a50D-3cjpA:undetectable | 3a50D-3cjpA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dgt | ENDO-1,3-BETA-GLUCANASE (Streptomycessioyaensis) |
PF00722(Glyco_hydro_16) | 5 | MET A 159ILE A 206LEU A 143ASN A 136ALA A 220 | None | 1.06A | 3a50D-3dgtA:undetectable | 3a50D-3dgtA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dm9 | SIGNAL RECOGNITIONPARTICLE RECEPTOR (Pyrococcusfuriosus) |
PF00448(SRP54)PF02881(SRP54_N) | 5 | ILE B 140LEU B 210LEU B 293THR B 270LEU B 304 | None | 0.94A | 3a50D-3dm9B:undetectable | 3a50D-3dm9B:22.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ejb | BIOTIN BIOSYNTHESISCYTOCHROME P450-LIKEENZYME (Bacillussubtilis) |
PF00067(p450) | 6 | MET B 79LEU B 164ASN B 181ILE B 233ALA B 234THR B 238 | NoneNoneNoneNoneHEM B 405 (-3.5A)HEM B 405 (-3.7A) | 0.81A | 3a50D-3ejbB:47.5 | 3a50D-3ejbB:36.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eoi | PILM (Escherichiacoli) |
PF07419(PilM) | 5 | LEU A 77ILE A 120ALA A 92THR A 102LEU A 82 | None | 1.11A | 3a50D-3eoiA:undetectable | 3a50D-3eoiA:15.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3goz | LEUCINE-RICHREPEAT-CONTAININGPROTEIN (Legionellapneumophila) |
no annotation | 5 | LEU A 92LEU A 85ASN A 57ILE A 107LEU A 143 | None | 1.07A | 3a50D-3gozA:undetectable | 3a50D-3gozA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hb0 | EYES ABSENT HOMOLOG2 (DROSOPHILA) (Homo sapiens) |
PF00702(Hydrolase) | 5 | ILE A 280LEU A 425ASN A 396THR A 449LEU A 445 | None | 1.04A | 3a50D-3hb0A:undetectable | 3a50D-3hb0A:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lki | FRUCTOKINASE (Xylellafastidiosa) |
PF00294(PfkB) | 5 | ILE A 300LEU A 304LEU A 235ALA A 251THR A 250 | None | 0.98A | 3a50D-3lkiA:undetectable | 3a50D-3lkiA:24.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nzm | DNA POLYMERASE IIISUBUNIT ALPHA (Synechocystissp. PCC 6803) |
no annotation | 5 | ILE A 66LEU A 60LEU A 95ILE A 156ALA A 157 | None | 1.08A | 3a50D-3nzmA:undetectable | 3a50D-3nzmA:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o6n | APL1 (Anophelesgambiae) |
PF00560(LRR_1)PF13855(LRR_8) | 5 | MET A 190ILE A 214LEU A 212ALA A 221LEU A 231 | None | 0.93A | 3a50D-3o6nA:undetectable | 3a50D-3o6nA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oja | ANOPHELESPLASMODIUM-RESPONSIVE LEUCINE-RICHREPEAT PROTEIN 1 (Anophelesgambiae) |
PF13855(LRR_8) | 5 | MET B 190ILE B 214LEU B 212ALA B 221LEU B 231 | None | 0.93A | 3a50D-3ojaB:undetectable | 3a50D-3ojaB:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p8c | NCK-ASSOCIATEDPROTEIN 1 (Homo sapiens) |
PF09735(Nckap1) | 5 | PRO B 188ILE B 267LEU B 189ILE B 138LEU B 293 | None | 0.96A | 3a50D-3p8cB:1.5 | 3a50D-3p8cB:17.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pj0 | LMO0305 PROTEIN (Listeriamonocytogenes) |
PF01212(Beta_elim_lyase) | 5 | ILE A 183LEU A 153LEU A 197ALA A 191LEU A 175 | None | 1.09A | 3a50D-3pj0A:undetectable | 3a50D-3pj0A:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pty | ARABINOSYLTRANSFERASE C (Mycobacteriumtuberculosis) |
PF14896(Arabino_trans_C) | 5 | PRO A1007LEU A1063LEU A 983ILE A1011ALA A1059 | None | 1.10A | 3a50D-3ptyA:undetectable | 3a50D-3ptyA:25.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3r9b | CYTOCHROME P450164A2 (Mycolicibacteriumsmegmatis) |
PF00067(p450) | 5 | LEU A 180ILE A 255ALA A 256THR A 260LEU A 184 | NoneD12 A 509 ( 4.1A)HEM A 501 ( 3.5A)HEM A 501 (-3.4A)D12 A 509 ( 4.3A) | 0.83A | 3a50D-3r9bA:48.9 | 3a50D-3r9bA:39.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vta | CUCUMISIN (Cucumis melo) |
PF00082(Peptidase_S8) | 5 | PRO A 454ILE A 394LEU A 361THR A 336LEU A 436 | None | 1.13A | 3a50D-3vtaA:undetectable | 3a50D-3vtaA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zyn | LEUCINE-RICHREPEAT-CONTAININGPROTEIN 4B (Mus musculus) |
PF00560(LRR_1)PF13855(LRR_8) | 5 | ILE A 246LEU A 243LEU A 236ASN A 215LEU A 284 | None | 0.99A | 3a50D-3zynA:undetectable | 3a50D-3zynA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4arc | LEUCINE--TRNA LIGASE (Escherichiacoli) |
PF00133(tRNA-synt_1)PF08264(Anticodon_1)PF13603(tRNA-synt_1_2) | 5 | ILE A 526LEU A 564ASN A 723MET A 647ALA A 63 | NoneNone A B 14 ( 3.4A)NoneNone | 1.13A | 3a50D-4arcA:undetectable | 3a50D-4arcA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bwc | PHOSPHOLIPASE B-LIKE1 (Bos taurus) |
PF04916(Phospholip_B) | 5 | ILE B 254LEU A 102ASN A 55ILE A 81LEU A 169 | None | 1.07A | 3a50D-4bwcB:undetectable | 3a50D-4bwcB:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cv5 | GENERAL NEGATIVEREGULATOR OFTRANSCRIPTIONSUBUNIT 1PROTEIN CAF40 (Saccharomycescerevisiae) |
PF04078(Rcd1)PF12842(DUF3819) | 5 | LEU B 203ILE A1114ALA A1115THR A1119LEU B 153 | None | 0.98A | 3a50D-4cv5B:undetectable | 3a50D-4cv5B:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dhe | PROBABLE GTP-BINDINGPROTEIN ENGB (Burkholderiathailandensis) |
PF01926(MMR_HSR1) | 5 | MET A 118ILE A 116LEU A 146ILE A 42LEU A 5 | None | 1.14A | 3a50D-4dheA:undetectable | 3a50D-4dheA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eco | UNCHARACTERIZEDPROTEIN (Bacteroideseggerthii) |
no annotation | 5 | ILE A 546LEU A 537LEU A 530ALA A 549LEU A 559 | None | 1.09A | 3a50D-4ecoA:undetectable | 3a50D-4ecoA:20.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4j6c | CYTOCHROME P450MONOOXYGENASE (Nocardiafarcinica) |
PF00067(p450) | 5 | ILE A 12LEU A 396LEU A 294ALA A 44THR A 46 | NoneFMT A 504 (-4.4A)HEM A 502 ( 4.0A)NoneNone | 1.04A | 3a50D-4j6cA:46.2 | 3a50D-4j6cA:33.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jyl | ENOYL-COA HYDRATASE (Thermoplasmavolcanium) |
PF00378(ECH_1) | 5 | MET A 65LEU A 30ILE A 25ALA A 24LEU A 2 | None | 1.04A | 3a50D-4jylA:undetectable | 3a50D-4jylA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4krf | PROTEIN ARGONAUTE-1 (Homo sapiens) |
PF02170(PAZ)PF02171(Piwi)PF08699(ArgoL1)PF16486(ArgoN)PF16487(ArgoMid)PF16488(ArgoL2) | 5 | PRO A 741MET A 211LEU A 145LEU A 154ALA A 159 | None | 1.06A | 3a50D-4krfA:undetectable | 3a50D-4krfA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nbq | POLYRIBONUCLEOTIDENUCLEOTIDYLTRANSFERASE (Coxiellaburnetii) |
PF00013(KH_1)PF00575(S1)PF01138(RNase_PH)PF03725(RNase_PH_C)PF03726(PNPase) | 5 | PRO A 97ILE A 137LEU A 98LEU A 131ILE A 218 | None | 1.08A | 3a50D-4nbqA:4.3 | 3a50D-4nbqA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r5d | LEUCINE RICH REPEATPROTEIN (syntheticconstruct) |
PF12354(Internalin_N)PF12799(LRR_4)PF13516(LRR_6)PF13855(LRR_8) | 5 | ILE A 325LEU A 349LEU A 309ILE A 305ALA A 301 | None | 0.89A | 3a50D-4r5dA:undetectable | 3a50D-4r5dA:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r5d | LEUCINE RICH REPEATPROTEIN (syntheticconstruct) |
PF12354(Internalin_N)PF12799(LRR_4)PF13516(LRR_6)PF13855(LRR_8) | 5 | ILE A 382LEU A 406LEU A 366ILE A 362ALA A 358 | None | 1.05A | 3a50D-4r5dA:undetectable | 3a50D-4r5dA:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r6g | LEUCINE RICH REPEATSDLRR_K (syntheticconstruct) |
PF12799(LRR_4)PF13516(LRR_6)PF13855(LRR_8) | 5 | ILE A 405LEU A 429LEU A 389ILE A 385ALA A 381 | None | 0.92A | 3a50D-4r6gA:undetectable | 3a50D-4r6gA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rwt | LEIOMODIN-2 (Homo sapiens) |
no annotation | 5 | ILE C 248ASN C 185ILE C 228ALA C 229LEU C 269 | None | 0.90A | 3a50D-4rwtC:undetectable | 3a50D-4rwtC:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rye | D-ALANYL-D-ALANINECARBOXYPEPTIDASE (Mycobacteriumtuberculosis) |
PF00768(Peptidase_S11) | 5 | LEU A 120LEU A 74ILE A 71ALA A 68THR A 240 | None | 1.12A | 3a50D-4ryeA:undetectable | 3a50D-4ryeA:23.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tzh | LIC12234 (Leptospirainterrogans) |
PF13855(LRR_8) | 5 | ILE A 95LEU A 72LEU A 87ILE A 84LEU A 113 | None | 1.12A | 3a50D-4tzhA:undetectable | 3a50D-4tzhA:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uhk | TRANSCRIPTIONALREGULATORY PROTEINCPXR (Escherichiacoli) |
PF00072(Response_reg) | 5 | ILE A 4LEU A 21LEU A 98ASN A 103ILE A 75 | None | 1.13A | 3a50D-4uhkA:undetectable | 3a50D-4uhkA:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wj7 | MALCAVERNIN (Homo sapiens) |
no annotation | 5 | ILE A 76LEU A 80LEU A 89ILE A 92ALA A 95 | None | 1.14A | 3a50D-4wj7A:undetectable | 3a50D-4wj7A:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yc7 | FORMIN-LIKE PROTEIN2 (Homo sapiens) |
PF06367(Drf_FH3)PF06371(Drf_GBD) | 5 | ILE B 283MET B 232ILE B 251ALA B 252LEU B 267 | None | 1.11A | 3a50D-4yc7B:undetectable | 3a50D-4yc7B:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yx5 | SURFACE PRESENTATIONOF ANTIGENS PROTEINSPAO (Salmonellaenterica) |
PF01052(FliMN_C)no annotation | 5 | ILE A 61LEU B 32ASN B 51ILE A 16ALA A 42 | None | 1.05A | 3a50D-4yx5A:undetectable | 3a50D-4yx5A:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yx5 | SURFACE PRESENTATIONOF ANTIGENS PROTEINSPAO (Salmonellaenterica) |
PF01052(FliMN_C)no annotation | 5 | PRO B 33ILE A 61LEU B 32ILE A 16ALA A 42 | None | 1.01A | 3a50D-4yx5B:undetectable | 3a50D-4yx5B:13.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z79 | LEIOMODIN-1ACTIN-BINDING SITE 2(ABS2) (Homo sapiens) |
no annotation | 5 | ILE A 399ASN A 336ILE A 379ALA A 380LEU A 420 | NoneGOL A 505 (-4.2A)NoneGOL A 502 (-3.6A)None | 0.97A | 3a50D-4z79A:undetectable | 3a50D-4z79A:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z8g | TROPOMODULIN-1,LEIOMODIN-1 CHIMERA(TP1 ABS2) (Homo sapiens) |
no annotation | 5 | ILE A 399ASN A 201ILE A 379ALA A 380LEU A 420 | None NI A 509 (-4.0A)NoneNoneNone | 0.87A | 3a50D-4z8gA:undetectable | 3a50D-4z8gA:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z94 | GELSOLIN,TROPOMODULIN-1,LEIOMODIN-1 CHIMERA (Homo sapiens) |
PF00626(Gelsolin) | 5 | ILE G1399ASN G1201ILE G1379ALA G1380LEU G1420 | None | 0.96A | 3a50D-4z94G:undetectable | 3a50D-4z94G:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bsw | 4-COUMARATE--COALIGASE 2 (Nicotianatabacum) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 5 | ILE A 288LEU A 230ASN A 86MET A 258ILE A 270 | None | 1.12A | 3a50D-5bswA:undetectable | 3a50D-5bswA:21.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 6 | LEU A 171ASN A 181MET A 184ILE A 235ALA A 236THR A 240 | NoneNoneNoneNoneHEM A 501 (-3.6A)HEM A 501 (-3.7A) | 1.40A | 3a50D-5gnmA:56.8 | 3a50D-5gnmA:98.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 6 | LEU A 171LYS A 180ASN A 181MET A 184ALA A 236THR A 240 | NoneNoneNoneNoneHEM A 501 (-3.6A)HEM A 501 (-3.7A) | 1.37A | 3a50D-5gnmA:56.8 | 3a50D-5gnmA:98.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 6 | PRO A 83MET A 86ILE A 88LEU A 89ILE A 235LEU A 387 | NoneNoneHEM A 501 ( 4.4A)NoneNoneNone | 0.81A | 3a50D-5gnmA:56.8 | 3a50D-5gnmA:98.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 6 | PRO A 83MET A 86ILE A 88LEU A 89ILE A 235THR A 240 | NoneNoneHEM A 501 ( 4.4A)NoneNoneHEM A 501 (-3.7A) | 0.42A | 3a50D-5gnmA:56.8 | 3a50D-5gnmA:98.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 6 | PRO A 83MET A 86LEU A 89ILE A 235ALA A 236LEU A 387 | NoneNoneNoneNoneHEM A 501 (-3.6A)None | 0.94A | 3a50D-5gnmA:56.8 | 3a50D-5gnmA:98.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 6 | PRO A 83MET A 86LEU A 89ILE A 235ALA A 236THR A 240 | NoneNoneNoneNoneHEM A 501 (-3.6A)HEM A 501 (-3.7A) | 0.73A | 3a50D-5gnmA:56.8 | 3a50D-5gnmA:98.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h0r | VP4 PROTEIN (Cypovirus 1) |
no annotation | 5 | PRO G 6ILE G 172LEU G 154ILE G 77ALA G 74 | None | 1.01A | 3a50D-5h0rG:undetectable | 3a50D-5h0rG:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h3x | FIBRONECTIN/FIBRINOGEN BINDING PROTEIN (Streptococcussuis) |
PF05833(FbpA) | 5 | ILE A 91LEU A 100LEU A 257ALA A 17LEU A 61 | None | 1.08A | 3a50D-5h3xA:undetectable | 3a50D-5h3xA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i6z | SODIUM-DEPENDENTSEROTONINTRANSPORTER (Homo sapiens) |
PF00209(SNF) | 5 | ILE A 552LEU A 549LEU A 337ILE A 333ALA A 329 | None | 1.06A | 3a50D-5i6zA:undetectable | 3a50D-5i6zA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ip7 | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB11DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB3 (Saccharomycescerevisiae) |
PF01000(RNA_pol_A_bac)PF01193(RNA_pol_L)PF13656(RNA_pol_L_2) | 5 | ILE K 46LEU K 50ASN K 29ILE K 33LEU C 262 | None | 1.14A | 3a50D-5ip7K:undetectable | 3a50D-5ip7K:13.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5izt | OUTER SURFACEPROTEIN (Borreliellaburgdorferi) |
PF05714(Borrelia_lipo_1) | 5 | MET A 285ILE A 284LEU A 288LEU A 393ALA A 365 | None | 1.06A | 3a50D-5iztA:undetectable | 3a50D-5iztA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j6q | CELL WALL BINDINGPROTEIN CWP8 (Clostridioidesdifficile) |
PF04122(CW_binding_2) | 5 | ILE A 344LEU A 535ASN A 507ILE A 327ALA A 326 | None | 1.08A | 3a50D-5j6qA:undetectable | 3a50D-5j6qA:20.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5l94 | CYTOCHROME P450 (Bacillusmegaterium) |
PF00067(p450) | 5 | ILE A 85LYS A 187ILE A 241ALA A 242THR A 246 | HEM A 501 (-4.4A)NoneTES A 502 (-4.0A)HEM A 501 (-3.5A)HEM A 501 (-3.4A) | 0.44A | 3a50D-5l94A:49.6 | 3a50D-5l94A:34.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5loi | RAD26 (Thermothelomycesthermophila) |
PF12331(DUF3636) | 5 | MET A 559ILE A 480LEU A 523ASN A 572ALA A 529 | None | 1.11A | 3a50D-5loiA:2.5 | 3a50D-5loiA:23.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m7r | PROTEIN O-GLCNACASE (Homo sapiens) |
PF07555(NAGidase) | 5 | PRO A 209ILE A 134LEU A 171ALA A 96LEU A 248 | None | 1.12A | 3a50D-5m7rA:undetectable | 3a50D-5m7rA:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nzg | UDP-GLUCOSEPYROPHOSPHORYLASE (Leishmaniamajor) |
no annotation | 5 | MET A 215ILE A 312LEU A 314ILE A 194LEU A 328 | None | 1.12A | 3a50D-5nzgA:undetectable | 3a50D-5nzgA:12.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uhk | O-GLCNACASETIM-BARREL DOMAIN (Homo sapiens) |
PF07555(NAGidase) | 5 | PRO A 209ILE A 134LEU A 171ALA A 96LEU A 248 | None | 1.13A | 3a50D-5uhkA:undetectable | 3a50D-5uhkA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uj7 | ORIGIN RECOGNITIONCOMPLEX SUBUNIT 4 (Homo sapiens) |
PF13191(AAA_16)PF14629(ORC4_C) | 6 | LEU C 99LEU C 140ASN C 135ILE C 187ALA C 188THR C 54 | None | 1.50A | 3a50D-5uj7C:undetectable | 3a50D-5uj7C:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uld | TRANSPORTER, NADCFAMILY (Vibrio cholerae) |
PF00939(Na_sulph_symp) | 5 | ILE A 426LEU A 183MET A 438ALA A 189THR A 142 | None | 1.04A | 3a50D-5uldA:undetectable | 3a50D-5uldA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5viu | ACETYLORNITHINEAMINOTRANSFERASE (Elizabethkingiaanophelis) |
PF00202(Aminotran_3) | 5 | ILE A 329LEU A 332LEU A 365ILE A 384LEU A 374 | None | 1.02A | 3a50D-5viuA:undetectable | 3a50D-5viuA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vvo | PROTEIN O-GLCNACASE (Homo sapiens) |
PF07555(NAGidase) | 5 | PRO A 209ILE A 134LEU A 171ALA A 96LEU A 248 | None | 1.10A | 3a50D-5vvoA:undetectable | 3a50D-5vvoA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y3j | TOLL-LIKE RECEPTOR 9 (Equus caballus) |
no annotation | 5 | ILE A 410LEU A 379LEU A 369ALA A 388LEU A 417 | None | 1.09A | 3a50D-5y3jA:undetectable | 3a50D-5y3jA:11.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y9w | POLLEN RECEPTOR-LIKEKINASE 6 (Arabidopsisthaliana) |
no annotation | 5 | ILE B 135LEU B 112LEU B 146THR B 165LEU B 173 | None | 1.08A | 3a50D-5y9wB:undetectable | 3a50D-5y9wB:11.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bii | GLYOXYLATE REDUCTASE (Pyrococcusyayanosii) |
no annotation | 5 | MET A 230ILE A 259LEU A 227LEU A 210LEU A 264 | None | 1.13A | 3a50D-6biiA:undetectable | 3a50D-6biiA:12.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bwc | POLYSACCHARIDEBIOSYNTHESIS PROTEINCAPD (Bacillusthuringiensis) |
no annotation | 5 | PRO A 286MET A 288ILE A 290ILE A 218ALA A 219 | None | 1.11A | 3a50D-6bwcA:undetectable | 3a50D-6bwcA:10.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c6l | V-TYPE PROTON ATPASESUBUNIT A, VACUOLARISOFORMV-TYPE PROTON ATPASESUBUNIT F (Saccharomycescerevisiae) |
no annotation | 5 | PRO O 45ILE A 755LEU O 30ASN O 34LEU O 24 | None | 1.03A | 3a50D-6c6lO:undetectable | 3a50D-6c6lO:12.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fnw | VOLUME-REGULATEDANION CHANNELSUBUNIT LRRC8A (Mus musculus) |
no annotation | 5 | LEU A 453LEU A 468ILE A 465ALA A 487LEU A 495 | None | 1.11A | 3a50D-6fnwA:undetectable | 3a50D-6fnwA:13.10 |