SIMILAR PATTERNS OF AMINO ACIDS FOR 3A50_C_VD3C2001
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bk6 | KARYOPHERIN ALPHA (Saccharomycescerevisiae) |
PF00514(Arm)PF16186(Arm_3) | 5 | ILE A 365LEU A 424ASN A 454LEU A 388ILE A 385 | None | 1.12A | 3a50C-1bk6A:2.9 | 3a50C-1bk6A:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bt0 | PROTEIN(UBIQUITIN-LIKEPROTEIN 7, RUB1) (Arabidopsisthaliana) |
PF00240(ubiquitin) | 5 | THR A 9ILE A 13LEU A 71ILE A 36LEU A 43 | None | 1.27A | 3a50C-1bt0A:undetectable | 3a50C-1bt0A:10.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cby | DELTA-ENDOTOXIN CYTB (Bacillusthuringiensis) |
PF01338(Bac_thur_toxin) | 5 | ILE A 87LEU A 81ASN A 76LEU A 222ILE A 92 | None | 1.30A | 3a50C-1cbyA:undetectable | 3a50C-1cbyA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eg1 | ENDOGLUCANASE I (Trichodermareesei) |
PF00840(Glyco_hydro_7) | 5 | ILE A 269LEU A 128LEU A 209ILE A 199LEU A 309 | None | 1.31A | 3a50C-1eg1A:undetectable | 3a50C-1eg1A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1elv | COMPLEMENT C1SCOMPONENT (Homo sapiens) |
PF00084(Sushi)PF00089(Trypsin) | 5 | THR A 663ILE A 495LEU A 456ASN A 451ILE A 515 | None | 1.24A | 3a50C-1elvA:undetectable | 3a50C-1elvA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1evj | GLUCOSE-FRUCTOSEOXIDOREDUCTASE (Zymomonasmobilis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | MET A 290ILE A 301ASN A 220LEU A 288ILE A 171 | None | 1.25A | 3a50C-1evjA:undetectable | 3a50C-1evjA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f9n | ARGININEREPRESSOR/ACTIVATORPROTEIN (Bacillussubtilis) |
PF01316(Arg_repressor)PF02863(Arg_repressor_C) | 5 | ILE A 130LEU A 146ILE A 87THR A 98LEU A 80 | None | 1.24A | 3a50C-1f9nA:undetectable | 3a50C-1f9nA:17.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gff | BACTERIOPHAGE G4CAPSID PROTEINS GPF,GPG, GPJ (Escherichiavirus G4) |
PF02305(Phage_F) | 5 | THR 1 406MET 1 404ILE 1 49ASN 1 409ILE 1 66 | None | 1.04A | 3a50C-1gff1:undetectable | 3a50C-1gff1:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h6d | PRECURSOR FORM OFGLUCOSE-FRUCTOSEOXIDOREDUCTASE (Zymomonasmobilis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | MET A 342ILE A 353ASN A 272LEU A 340ILE A 223 | None | 1.20A | 3a50C-1h6dA:0.0 | 3a50C-1h6dA:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hp1 | 5'-NUCLEOTIDASE (Escherichiacoli) |
PF00149(Metallophos)PF02872(5_nucleotid_C) | 5 | THR A 216ILE A 213LEU A 240MET A 236ILE A 283 | None | 1.27A | 3a50C-1hp1A:undetectable | 3a50C-1hp1A:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hww | ALPHA-MANNOSIDASE II (Drosophilamelanogaster) |
PF01074(Glyco_hydro_38)PF07748(Glyco_hydro_38C)PF09261(Alpha-mann_mid) | 5 | THR A 162ILE A 127ILE A 203THR A 274LEU A 335 | None | 1.30A | 3a50C-1hwwA:undetectable | 3a50C-1hwwA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1igr | INSULIN-LIKE GROWTHFACTOR RECEPTOR 1 (Homo sapiens) |
PF00757(Furin-like)PF01030(Recep_L_domain) | 5 | MET A 92ILE A 89LEU A 69LEU A 95LEU A 100 | None | 1.29A | 3a50C-1igrA:undetectable | 3a50C-1igrA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kyh | HYPOTHETICAL 29.9KDA PROTEIN INSIGY-CYDD INTERGENICREGION (Bacillussubtilis) |
PF01256(Carb_kinase) | 5 | THR A 157MET A 156LEU A 185LEU A 132THR A 219 | None | 1.28A | 3a50C-1kyhA:undetectable | 3a50C-1kyhA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o20 | GAMMA-GLUTAMYLPHOSPHATE REDUCTASE (Thermotogamaritima) |
PF00171(Aldedh) | 5 | THR A 292ILE A 275LEU A 261ILE A 316THR A 249 | None | 1.12A | 3a50C-1o20A:undetectable | 3a50C-1o20A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q8f | PYRIMIDINENUCLEOSIDE HYDROLASE (Escherichiacoli) |
PF01156(IU_nuc_hydro) | 5 | LEU A 121ASN A 129LEU A 141ILE A 144LEU A 184 | None | 1.30A | 3a50C-1q8fA:undetectable | 3a50C-1q8fA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r3n | BETA-ALANINESYNTHASE (Lachanceakluyveri) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | ILE A 432ASN A 422LEU A 128ILE A 127LEU A 40 | None | 1.22A | 3a50C-1r3nA:undetectable | 3a50C-1r3nA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rkv | HOMOSERINE KINASE (Pseudomonasaeruginosa) |
PF12710(HAD) | 5 | ILE A 116LEU A 55LEU A 57ILE A 60LEU A 47 | None | 1.27A | 3a50C-1rkvA:undetectable | 3a50C-1rkvA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s8e | EXONUCLEASE PUTATIVE (Pyrococcusfuriosus) |
PF00149(Metallophos) | 5 | ILE A 296LEU A 320LEU A 292ILE A 289LEU A 326 | None | 1.29A | 3a50C-1s8eA:undetectable | 3a50C-1s8eA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sdd | COAGULATION FACTOR V (Bos taurus) |
PF00754(F5_F8_type_C)PF07732(Cu-oxidase_3) | 5 | ILE B2000LEU B2013ASN B1980ILE B1922LEU B1872 | None | 1.26A | 3a50C-1sddB:undetectable | 3a50C-1sddB:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1suv | TRANSFERRIN RECEPTORPROTEIN 1 (Homo sapiens) |
PF02225(PA)PF04253(TFR_dimer)PF04389(Peptidase_M28) | 5 | MET A 635ILE A 632LEU A 637THR A 739LEU A 712 | None | 1.21A | 3a50C-1suvA:undetectable | 3a50C-1suvA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ua2 | CELL DIVISIONPROTEIN KINASE 7 (Homo sapiens) |
PF00069(Pkinase) | 5 | ILE A 114LEU A 143ASN A 73LEU A 203ILE A 202 | None | 1.15A | 3a50C-1ua2A:undetectable | 3a50C-1ua2A:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vma | CELL DIVISIONPROTEIN FTSY (Thermotogamaritima) |
PF00448(SRP54)PF02881(SRP54_N) | 5 | ILE A 259LEU A 215ASN A 86LEU A 244THR A 103 | None | 1.17A | 3a50C-1vmaA:2.4 | 3a50C-1vmaA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vma | CELL DIVISIONPROTEIN FTSY (Thermotogamaritima) |
PF00448(SRP54)PF02881(SRP54_N) | 5 | LEU A 215ASN A 86LEU A 244ILE A 243THR A 103 | None | 1.19A | 3a50C-1vmaA:2.4 | 3a50C-1vmaA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wa5 | IMPORTIN ALPHASUBUNIT (Saccharomycescerevisiae) |
PF00514(Arm)PF01749(IBB)PF16186(Arm_3) | 5 | ILE B 365LEU B 424ASN B 454LEU B 388ILE B 385 | None | 1.10A | 3a50C-1wa5B:3.0 | 3a50C-1wa5B:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x7f | OUTER SURFACEPROTEIN (Bacillus cereus) |
PF05913(DUF871) | 5 | ILE A 163ASN A 122LEU A 219ILE A 220LEU A 199 | None | 1.06A | 3a50C-1x7fA:undetectable | 3a50C-1x7fA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xp3 | ENDONUCLEASE IV (Bacillusanthracis) |
PF01261(AP_endonuc_2) | 5 | ILE A 238LEU A 214LEU A 243ILE A 216THR A 261 | None | 1.00A | 3a50C-1xp3A:undetectable | 3a50C-1xp3A:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xp8 | RECA PROTEIN (Deinococcusradiodurans) |
PF00154(RecA) | 5 | THR A 54ILE A 76LEU A 273LEU A 235ILE A 257 | None | 1.31A | 3a50C-1xp8A:undetectable | 3a50C-1xp8A:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z68 | FIBROBLASTACTIVATION PROTEIN,ALPHA SUBUNIT (Homo sapiens) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | ILE A 713LEU A 634ASN A 691LEU A 696LEU A 632 | None | 0.97A | 3a50C-1z68A:undetectable | 3a50C-1z68A:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b8n | GLYCERATE KINASE,PUTATIVE (Thermotogamaritima) |
PF05161(MOFRL)PF13660(DUF4147) | 5 | LEU A 399LEU A 345ILE A 363THR A 368LEU A 392 | None | 1.24A | 3a50C-2b8nA:undetectable | 3a50C-2b8nA:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fv5 | ADAM 17 (Homo sapiens) |
PF13688(Reprolysin_5) | 5 | THR A 403LEU A 227ASN A 410LEU A 251ILE A 279 | None | 1.20A | 3a50C-2fv5A:undetectable | 3a50C-2fv5A:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h12 | CITRATE SYNTHASE (Acetobacteraceti) |
PF00285(Citrate_synt) | 5 | MET A 381ILE A 377LEU A 231ASN A 200LEU A 233 | None | 1.13A | 3a50C-2h12A:undetectable | 3a50C-2h12A:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iwo | MULTIPLE PDZ DOMAINPROTEIN (Homo sapiens) |
PF00595(PDZ) | 5 | THR A1876MET A1837ILE A1912LEU A1845ILE A1847 | None | 1.27A | 3a50C-2iwoA:undetectable | 3a50C-2iwoA:17.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ke5 | RAS-RELATED PROTEINRAL-B (Homo sapiens) |
PF00071(Ras) | 5 | THR A 31ASN A 128LEU A 67ILE A 18LEU A 72 | NoneGNP A 500 (-4.7A)NoneNoneNone | 1.26A | 3a50C-2ke5A:undetectable | 3a50C-2ke5A:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2np0 | BOTULINUM NEUROTOXINTYPE B (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07951(Toxin_R_bind_C)PF07952(Toxin_trans)PF07953(Toxin_R_bind_N) | 5 | ILE A 111ASN A 363LEU A 235ILE A 232THR A 171 | None | 1.20A | 3a50C-2np0A:undetectable | 3a50C-2np0A:15.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2quq | CENTROMEREDNA-BINDING PROTEINCOMPLEX CBF3 SUBUNITB (Saccharomycescerevisiae) |
PF16846(Cep3) | 5 | MET A 174ILE A 171LEU A 179ILE A 182LEU A 106 | None | 1.03A | 3a50C-2quqA:undetectable | 3a50C-2quqA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2sfa | SERINE PROTEINASE (Streptomycesfradiae) |
PF00089(Trypsin) | 5 | LEU A 135ASN A 64LEU A 151THR A 118LEU A 120 | None | 1.20A | 3a50C-2sfaA:undetectable | 3a50C-2sfaA:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wlc | POLYSIALIC ACIDO-ACETYLTRANSFERASE (Neisseriameningitidis) |
PF00132(Hexapep) | 5 | THR A 86MET A 88ILE A 67ILE A 93LEU A 59 | None | 1.32A | 3a50C-2wlcA:undetectable | 3a50C-2wlcA:16.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xkr | PUTATIVE CYTOCHROMEP450 142 (Mycobacteriumtuberculosis) |
PF00067(p450) | 5 | ILE A 76LEU A 159LEU A 226ILE A 229THR A 234 | HEM A1400 (-4.1A)NoneHEM A1400 (-4.4A)PG4 A1399 ( 4.5A)HEM A1400 (-3.7A) | 0.76A | 3a50C-2xkrA:44.9 | 3a50C-2xkrA:35.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xkr | PUTATIVE CYTOCHROMEP450 142 (Mycobacteriumtuberculosis) |
PF00067(p450) | 5 | MET A 74ILE A 76LEU A 159LEU A 226THR A 234 | PG4 A1399 ( 4.4A)HEM A1400 (-4.1A)NoneHEM A1400 (-4.4A)HEM A1400 (-3.7A) | 0.73A | 3a50C-2xkrA:44.9 | 3a50C-2xkrA:35.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2zbz | CYTOCHROME P450-SU1 (Streptomycesgriseolus) |
PF00067(p450) | 5 | ILE A 96LEU A 180LEU A 240ILE A 243THR A 248 | HEM A 413 (-4.0A)VDX A 501 (-4.2A)HEM A 413 ( 4.5A)VDX A 501 (-4.2A)HEM A 413 (-3.2A) | 0.66A | 3a50C-2zbzA:47.8 | 3a50C-2zbzA:37.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aal | PROBABLEENDONUCLEASE 4 (Geobacilluskaustophilus) |
PF01261(AP_endonuc_2) | 5 | ILE A 237LEU A 213LEU A 242ILE A 215THR A 260 | None | 1.03A | 3a50C-3aalA:undetectable | 3a50C-3aalA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aiz | DNA POLYMERASESLIDING CLAMP C (Sulfurisphaeratokodaii) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | THR C 75ILE C 25LEU C 18ILE C 14LEU C 34 | None | 1.12A | 3a50C-3aizC:undetectable | 3a50C-3aizC:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3al0 | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNITC,LINKER,GLUTAMATE--TRNA LIGASE 2 (Thermotogamaritima;syntheticconstruct) |
PF00749(tRNA-synt_1c)PF02686(Glu-tRNAGln) | 5 | THR C 562LEU C 572LEU C 565ILE C 569LEU C 581 | U E 35 ( 4.6A)None C E 34 ( 3.9A)NoneNone | 1.21A | 3a50C-3al0C:undetectable | 3a50C-3al0C:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cue | TRANSPORT PROTEINPARTICLE 18 KDASUBUNITTRANSPORT PROTEINPARTICLE 23 KDASUBUNIT (Saccharomycescerevisiae) |
PF04099(Sybindin) | 5 | THR A 124ILE A 143LEU C 51LEU C 58ILE C 54 | None | 1.25A | 3a50C-3cueA:undetectable | 3a50C-3cueA:17.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ejb | BIOTIN BIOSYNTHESISCYTOCHROME P450-LIKEENZYME (Bacillussubtilis) |
PF00067(p450) | 6 | MET B 79LEU B 164ASN B 181LEU B 230ILE B 233THR B 238 | NoneNoneNoneHEM B 405 ( 4.6A)NoneHEM B 405 (-3.7A) | 0.82A | 3a50C-3ejbB:47.5 | 3a50C-3ejbB:36.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fz4 | PUTATIVE ARSENATEREDUCTASE (Streptococcusmutans) |
PF03960(ArsC) | 5 | ILE A 92LEU A 51LEU A 96ILE A 103LEU A 46 | NoneNoneNoneFMT A 205 (-4.6A)None | 1.07A | 3a50C-3fz4A:undetectable | 3a50C-3fz4A:17.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gq2 | GENERAL VESICULARTRANSPORT FACTORP115 (Bos taurus) |
PF04869(Uso1_p115_head) | 5 | ILE A 624LEU A 540LEU A 581ILE A 584LEU A 616 | None | 1.32A | 3a50C-3gq2A:2.2 | 3a50C-3gq2A:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h5o | TRANSCRIPTIONALREGULATOR GNTR (Chromobacteriumviolaceum) |
PF13377(Peripla_BP_3) | 6 | THR A 133MET A 155ILE A 305LEU A 89ASN A 107ILE A 92 | NoneNoneNoneNoneSO4 A 1 (-3.2A)None | 1.35A | 3a50C-3h5oA:undetectable | 3a50C-3h5oA:25.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hn7 | UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE (Psychrobacterarcticus) |
PF01225(Mur_ligase)PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 5 | LEU A 349MET A 120LEU A 329ILE A 332THR A 312 | None | 1.27A | 3a50C-3hn7A:undetectable | 3a50C-3hn7A:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hyi | PROTEIN DUF199/WHIA (Thermotogamaritima) |
PF02650(HTH_WhiA)PF10298(WhiA_N)PF14527(LAGLIDADG_WhiA) | 5 | ILE A 13LEU A 115LEU A 182ILE A 185LEU A 120 | None | 1.24A | 3a50C-3hyiA:undetectable | 3a50C-3hyiA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iec | SERINE/THREONINE-PROTEIN KINASE MARK2 (Homo sapiens) |
PF00069(Pkinase)PF00627(UBA) | 5 | LEU A 181ASN A 111LEU A 240ILE A 239LEU A 141 | None | 1.31A | 3a50C-3iecA:undetectable | 3a50C-3iecA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iuz | PUTATIVE GLYOXALASESUPERFAMILY PROTEIN (Cupriaviduspinatubonensis) |
PF07063(DUF1338) | 5 | THR A 40ILE A 138LEU A 8LEU A 31ILE A 5 | None | 1.31A | 3a50C-3iuzA:undetectable | 3a50C-3iuzA:24.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kjr | DIHYDROFOLATEREDUCTASE/THYMIDYLATE SYNTHASE (Babesia bovis) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 5 | ILE A 108LEU A 123LEU A 11ILE A 122LEU A 88 | NoneNoneNoneNoneNAP A 512 (-4.4A) | 1.16A | 3a50C-3kjrA:undetectable | 3a50C-3kjrA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lou | FORMYLTETRAHYDROFOLATE DEFORMYLASE (Burkholderiamallei) |
PF00551(Formyl_trans_N) | 5 | MET A 122ILE A 124LEU A 268ILE A 175LEU A 108 | None | 1.26A | 3a50C-3louA:undetectable | 3a50C-3louA:24.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mtl | CELL DIVISIONPROTEIN KINASE 16 (Homo sapiens) |
PF00069(Pkinase) | 5 | MET A 355ILE A 258LEU A 300ILE A 294LEU A 470 | None | 1.29A | 3a50C-3mtlA:undetectable | 3a50C-3mtlA:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nyw | PUTATIVEOXIDOREDUCTASE (Bacteroidesthetaiotaomicron) |
PF00106(adh_short) | 5 | ILE A 35LEU A 7LEU A 62THR A 125LEU A 89 | None | 1.19A | 3a50C-3nywA:undetectable | 3a50C-3nywA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3onk | EPSIN-3 (Saccharomycescerevisiae) |
PF01417(ENTH) | 5 | THR A 59LEU A 93LEU A 69ILE A 72LEU A 143 | None | 1.04A | 3a50C-3onkA:undetectable | 3a50C-3onkA:15.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r8x | METHIONYL-TRNAFORMYLTRANSFERASE (Yersinia pestis) |
PF00551(Formyl_trans_N)PF02911(Formyl_trans_C) | 5 | ILE A 273LYS A 214LEU A 287ILE A 246LEU A 314 | None | 1.31A | 3a50C-3r8xA:undetectable | 3a50C-3r8xA:24.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3r9b | CYTOCHROME P450164A2 (Mycolicibacteriumsmegmatis) |
PF00067(p450) | 5 | LEU A 180LEU A 252ILE A 255THR A 260LEU A 184 | NoneHEM A 501 ( 4.5A)D12 A 509 ( 4.1A)HEM A 501 (-3.4A)D12 A 509 ( 4.3A) | 0.94A | 3a50C-3r9bA:49.2 | 3a50C-3r9bA:39.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s29 | SUCROSE SYNTHASE 1 (Arabidopsisthaliana) |
PF00534(Glycos_transf_1)PF00862(Sucrose_synth) | 5 | THR A 393LEU A 429LEU A 284ILE A 411LEU A 404 | None | 1.32A | 3a50C-3s29A:undetectable | 3a50C-3s29A:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sqn | CONSERVED DOMAINPROTEIN (Enterococcusfaecalis) |
PF05043(Mga) | 5 | LEU A 88ASN A 81LEU A 97ILE A 94THR A 10 | None | 1.20A | 3a50C-3sqnA:undetectable | 3a50C-3sqnA:23.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ulk | KETOL-ACIDREDUCTOISOMERASE (Escherichiacoli) |
PF01450(IlvC)PF07991(IlvN) | 5 | THR A 198MET A 56ILE A 63LEU A 105ILE A 103 | THR A 198 ( 0.8A)MET A 56 ( 0.0A)ILE A 63 ( 0.7A)LEU A 105 (-0.5A)ILE A 103 ( 0.7A) | 1.31A | 3a50C-3ulkA:undetectable | 3a50C-3ulkA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uwc | NUCLEOTIDE-SUGARAMINOTRANSFERASE (Coxiellaburnetii) |
PF01041(DegT_DnrJ_EryC1) | 5 | ILE A 196LEU A 186ASN A 238MET A 241ILE A 160 | None | 1.21A | 3a50C-3uwcA:undetectable | 3a50C-3uwcA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vvj | OVALBUMIN (Dromaiusnovaehollandiae) |
PF00079(Serpin) | 5 | ILE A 58ASN A 375ILE A 63THR A 76LEU A 84 | None | 1.28A | 3a50C-3vvjA:undetectable | 3a50C-3vvjA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vwa | CYTOPLASMIC EXPORTPROTEIN 1 (Saccharomycescerevisiae) |
no annotation | 5 | ILE A 331LEU A 325LEU A 296ILE A 300LEU A 364 | None | 1.31A | 3a50C-3vwaA:2.1 | 3a50C-3vwaA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wwy | D-LACTATEDEHYDROGENASE (Fusobacteriumnucleatum) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | ILE A 255LYS A 121ASN A 123LEU A 232ILE A 231 | NoneGOL A 405 (-3.1A)NoneNoneNone | 1.28A | 3a50C-3wwyA:undetectable | 3a50C-3wwyA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zuq | BOTULINUM NEUROTOXINTYPE B (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07952(Toxin_trans) | 5 | ILE A 112ASN A 364LEU A 236ILE A 233THR A 172 | None | 1.18A | 3a50C-3zuqA:undetectable | 3a50C-3zuqA:16.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a8e | PROBABLE TYROSINERECOMBINASEXERC-LIKE (Pyrococcusabyssi) |
PF00589(Phage_integrase)PF02899(Phage_int_SAM_1) | 5 | ILE A 169LEU A 124LEU A 174ILE A 177LEU A 142 | None | 1.28A | 3a50C-4a8eA:2.7 | 3a50C-4a8eA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4azc | BETA-N-ACETYLHEXOSAMINIDASE (Streptococcuspneumoniae) |
PF00728(Glyco_hydro_20) | 5 | LEU A 887LEU A 868ILE A 869THR A 897LEU A 931 | NoneNoneNone MG A2045 (-4.7A)None | 1.26A | 3a50C-4azcA:undetectable | 3a50C-4azcA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c3s | ALDEHYDEDEHYDROGENASE (Lachnoclostridiumphytofermentans) |
PF00171(Aldedh) | 5 | ILE A 343LEU A 309ASN A 319LEU A 329ILE A 332 | None | 1.14A | 3a50C-4c3sA:undetectable | 3a50C-4c3sA:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c90 | ALPHA-GLUCURONIDASEGH115 (Bacteroidesovatus) |
PF15979(Glyco_hydro_115) | 5 | MET A 477ILE A 473LEU A 239ILE A 236LEU A 204 | None | 0.95A | 3a50C-4c90A:1.8 | 3a50C-4c90A:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ml9 | UNCHARACTERIZEDPROTEIN (Sebaldellatermitidis) |
PF00977(His_biosynth) | 5 | THR A 250ILE A 218LEU A 255ASN A 253ILE A 239 | NoneNoneNoneEDO A 309 (-3.3A)None | 1.23A | 3a50C-4ml9A:undetectable | 3a50C-4ml9A:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o8q | COATOMER SUBUNITDELTA (Bos taurus) |
PF00928(Adap_comp_sub) | 5 | THR A 368MET A 295ILE A 282LEU A 284LEU A 402 | None | 1.30A | 3a50C-4o8qA:undetectable | 3a50C-4o8qA:18.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pv4 | PROLINEAMINOPEPTIDASE P II (Yersinia pestis) |
PF00557(Peptidase_M24)PF05195(AMP_N) | 5 | ILE A 295LEU A 379LEU A 299ILE A 408THR A 419 | None | 1.24A | 3a50C-4pv4A:undetectable | 3a50C-4pv4A:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r3u | 2-HYDROXYISOBUTYRYL-COA MUTASE LARGESUBUNIT (Aquincolatertiaricarbonis) |
PF01642(MM_CoA_mutase) | 5 | ILE A 168ASN A 527MET A 529LEU A 175ILE A 174 | None | 1.22A | 3a50C-4r3uA:undetectable | 3a50C-4r3uA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r5c | LEUCINE RICH REPEATPROTEIN (syntheticconstruct) |
PF12354(Internalin_N)PF12799(LRR_4)PF13516(LRR_6)PF13855(LRR_8) | 5 | ILE A 216LEU A 185ASN A 162LEU A 195LEU A 231 | None | 1.00A | 3a50C-4r5cA:undetectable | 3a50C-4r5cA:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r6f | LEUCINE RICH REPEATDLRR_I (syntheticconstruct) |
PF12354(Internalin_N)PF13855(LRR_8) | 5 | ILE A 144LEU A 113ASN A 90LEU A 123LEU A 161 | None | 1.22A | 3a50C-4r6fA:undetectable | 3a50C-4r6fA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r7o | GLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE,PUTATIVE (Bacillusanthracis) |
PF03009(GDPD) | 5 | ILE A 139LEU A 166LEU A 71ILE A 151LEU A 175 | None | 1.25A | 3a50C-4r7oA:undetectable | 3a50C-4r7oA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rwt | LEIOMODIN-2 (Homo sapiens) |
no annotation | 5 | THR C 218ILE C 248ASN C 185ILE C 228LEU C 269 | None | 0.83A | 3a50C-4rwtC:undetectable | 3a50C-4rwtC:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u28 | PHOSPHORIBOSYLISOMERASE A (Streptomycessviceus) |
PF00977(His_biosynth) | 5 | ILE A 129LEU A 84LEU A 107ILE A 88LEU A 98 | None | 1.28A | 3a50C-4u28A:undetectable | 3a50C-4u28A:23.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x2r | 1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO]IMIDAZOLE-4-CARBOXAMIDE ISOMERASE (Actinomycesurogenitalis) |
PF00977(His_biosynth) | 5 | ILE A 123LEU A 78LEU A 101ILE A 82LEU A 92 | None | 1.25A | 3a50C-4x2rA:undetectable | 3a50C-4x2rA:23.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x9s | PHOSPHORIBOSYLISOMERASE A (Streptomycessp. Mg1) |
PF00977(His_biosynth) | 5 | ILE A 127LEU A 82LEU A 105ILE A 86LEU A 96 | None | 1.28A | 3a50C-4x9sA:undetectable | 3a50C-4x9sA:24.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xrl | MITOGEN-ACTIVATEDPROTEIN KINASE 1 (Rattusnorvegicus) |
PF00069(Pkinase) | 5 | ILE A 124LEU A 153LEU A 216ILE A 215LEU A 114 | None | 1.25A | 3a50C-4xrlA:undetectable | 3a50C-4xrlA:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z79 | LEIOMODIN-1ACTIN-BINDING SITE 2(ABS2) (Homo sapiens) |
no annotation | 5 | THR A 369ILE A 399ASN A 336ILE A 379LEU A 420 | NoneNoneGOL A 505 (-4.2A)NoneNone | 0.79A | 3a50C-4z79A:undetectable | 3a50C-4z79A:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z8g | TROPOMODULIN-1,LEIOMODIN-1 CHIMERA(TP1 ABS2) (Homo sapiens) |
no annotation | 5 | THR A 369ILE A 399ASN A 201ILE A 379LEU A 420 | NoneNone NI A 509 (-4.0A)NoneNone | 0.75A | 3a50C-4z8gA:undetectable | 3a50C-4z8gA:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z94 | GELSOLIN,TROPOMODULIN-1,LEIOMODIN-1 CHIMERA (Homo sapiens) |
PF00626(Gelsolin) | 5 | THR G1369ILE G1399ASN G1201ILE G1379LEU G1420 | None | 0.80A | 3a50C-4z94G:undetectable | 3a50C-4z94G:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zg5 | 5'-NUCLEOTIDASE SURE (Brucellaabortus) |
no annotation | 5 | THR D 181ILE D 224LEU D 165ILE D 229THR D 140 | None | 1.20A | 3a50C-4zg5D:undetectable | 3a50C-4zg5D:25.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b83 | TETRA UBIQUITIN (Homo sapiens) |
PF00240(ubiquitin) | 5 | THR A 85ILE A 89LEU A 147ILE A 112LEU A 119 | None | 1.19A | 3a50C-5b83A:undetectable | 3a50C-5b83A:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ey8 | ACYL-COA SYNTHASE (Mycolicibacteriumsmegmatis) |
PF00501(AMP-binding) | 5 | ILE A 103LEU A 204LEU A 184ILE A 199THR A 429 | None | 1.22A | 3a50C-5ey8A:undetectable | 3a50C-5ey8A:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fai | RIBOSOMAL RNA SMALLSUBUNITMETHYLTRANSFERASENEP1 (Homo sapiens) |
PF03587(EMG1) | 5 | ILE A 118ASN A 65LEU A 140THR A 124LEU A 92 | NoneUNX A 304 ( 4.1A)NoneNoneNone | 1.09A | 3a50C-5faiA:undetectable | 3a50C-5faiA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fb8 | PRO-INTERLEUKIN-16 (Homo sapiens) |
PF00595(PDZ) | 5 | THR C 88ILE C 82LEU C 105ILE C 102LEU C 35 | None | 1.20A | 3a50C-5fb8C:undetectable | 3a50C-5fb8C:14.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fb8 | PRO-INTERLEUKIN-16 (Homo sapiens) |
PF00595(PDZ) | 5 | THR C 88MET C 90ILE C 82LEU C 105ILE C 102 | None | 1.25A | 3a50C-5fb8C:undetectable | 3a50C-5fb8C:14.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 6 | THR A 84MET A 86ILE A 88LEU A 232ILE A 235THR A 240 | NoneNoneHEM A 501 ( 4.4A)HEM A 501 ( 4.7A)NoneHEM A 501 (-3.7A) | 0.43A | 3a50C-5gnmA:56.6 | 3a50C-5gnmA:98.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hwi | GLUTATHIONE-SPECIFICGAMMA-GLUTAMYLCYCLOTRANSFERASE (Saccharomycescerevisiae) |
PF04752(ChaC) | 5 | ILE A 17ASN A 131LEU A 204ILE A 93LEU A 11 | None | 1.21A | 3a50C-5hwiA:undetectable | 3a50C-5hwiA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j44 | SERINE PROTEASE SEPAAUTOTRANSPORTER (Shigellaflexneri) |
PF02395(Peptidase_S6) | 5 | THR A 191LEU A 231ASN A 207LEU A 178THR A 244 | None | 1.15A | 3a50C-5j44A:undetectable | 3a50C-5j44A:17.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jse | PHIAB6 TAILSPIKE (unidentifiedphage) |
PF12708(Pectate_lyase_3) | 5 | ILE A 161ASN A 220LEU A 186ILE A 183LEU A 138 | None | 1.21A | 3a50C-5jseA:undetectable | 3a50C-5jseA:19.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5l94 | CYTOCHROME P450 (Bacillusmegaterium) |
PF00067(p450) | 5 | ILE A 85LYS A 187LEU A 238ILE A 241THR A 246 | HEM A 501 (-4.4A)NoneHEM A 501 (-4.4A)TES A 502 (-4.0A)HEM A 501 (-3.4A) | 0.36A | 3a50C-5l94A:49.8 | 3a50C-5l94A:34.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m1m | MATRIX PROTEIN 1 (Influenza Cvirus) |
PF03026(CM1) | 5 | ILE A 29LEU A 48ILE A 43THR A 57LEU A 14 | None | 1.23A | 3a50C-5m1mA:undetectable | 3a50C-5m1mA:16.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xwy | A TYPE VI-ACRISPR-CASRNA-GUIDED RNARIBONUCLEASE, CAS13A (Leptotrichiabuccalis) |
no annotation | 5 | ILE A 563LEU A 699ASN A 695ILE A 702LEU A 596 | None | 1.31A | 3a50C-5xwyA:2.7 | 3a50C-5xwyA:14.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ep3 | - (-) |
no annotation | 5 | ILE A 20ASN A 65LEU A 54ILE A 51LEU A 36 | None | 1.25A | 3a50C-6ep3A:1.6 | 3a50C-6ep3A:undetectable |