SIMILAR PATTERNS OF AMINO ACIDS FOR 3A50_B_VD3B2001_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bk6 | KARYOPHERIN ALPHA (Saccharomycescerevisiae) |
PF00514(Arm)PF16186(Arm_3) | 5 | ILE A 365LEU A 424ASN A 454LEU A 388ILE A 385 | None | 1.16A | 3a50B-1bk6A:3.1 | 3a50B-1bk6A:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1buc | BUTYRYL-COADEHYDROGENASE (Megasphaeraelsdenii) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | THR A 51LEU A 123LEU A 45ILE A 42THR A 210 | None | 1.39A | 3a50B-1bucA:2.0 | 3a50B-1bucA:22.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cby | DELTA-ENDOTOXIN CYTB (Bacillusthuringiensis) |
PF01338(Bac_thur_toxin) | 5 | ILE A 87LEU A 81ASN A 76LEU A 222ILE A 92 | None | 1.26A | 3a50B-1cbyA:undetectable | 3a50B-1cbyA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cqq | TYPE 2 RHINOVIRUS 3CPROTEASE (Rhinovirus A) |
PF00548(Peptidase_C3) | 5 | ILE A 160LEU A 70ASN A 124LEU A 174PRO A 38 | None | 1.36A | 3a50B-1cqqA:undetectable | 3a50B-1cqqA:14.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1elv | COMPLEMENT C1SCOMPONENT (Homo sapiens) |
PF00084(Sushi)PF00089(Trypsin) | 5 | THR A 663ILE A 495LEU A 456ASN A 451ILE A 515 | None | 1.26A | 3a50B-1elvA:undetectable | 3a50B-1elvA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1evj | GLUCOSE-FRUCTOSEOXIDOREDUCTASE (Zymomonasmobilis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | MET A 290ILE A 301ASN A 220LEU A 288ILE A 171 | None | 1.23A | 3a50B-1evjA:undetectable | 3a50B-1evjA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gff | BACTERIOPHAGE G4CAPSID PROTEINS GPF,GPG, GPJ (Escherichiavirus G4) |
PF02305(Phage_F) | 5 | THR 1 406MET 1 404ILE 1 49ASN 1 409ILE 1 66 | None | 1.05A | 3a50B-1gff1:undetectable | 3a50B-1gff1:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h6d | PRECURSOR FORM OFGLUCOSE-FRUCTOSEOXIDOREDUCTASE (Zymomonasmobilis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | MET A 342ILE A 353ASN A 272LEU A 340ILE A 223 | None | 1.17A | 3a50B-1h6dA:0.0 | 3a50B-1h6dA:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k4y | LIVERCARBOXYLESTERASE (Oryctolaguscuniculus) |
PF00135(COesterase) | 5 | ILE A 334ASN A 238LEU A 232THR A 320PRO A 328 | None | 1.36A | 3a50B-1k4yA:0.0 | 3a50B-1k4yA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kr1 | HEVAMINE A (Heveabrasiliensis) |
PF00704(Glyco_hydro_18) | 5 | ILE A 44LEU A 16ASN A 62LEU A 76ILE A 30 | NoneSO4 A 801 (-4.5A)NoneNoneNone | 1.40A | 3a50B-1kr1A:undetectable | 3a50B-1kr1A:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lm7 | SUBDOMAIN OFDESMOPLAKINCARBOXY-TERMINALDOMAIN (DPCT) (Homo sapiens) |
PF00681(Plectin) | 5 | THR A2287ILE A2263LEU A2429ASN A2423ILE A2260 | None | 1.37A | 3a50B-1lm7A:undetectable | 3a50B-1lm7A:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n0w | DNA REPAIR PROTEINRAD51 HOMOLOG 1 (Homo sapiens) |
PF08423(Rad51) | 5 | ILE A 117LEU A 219LEU A 140ILE A 220THR A 266 | None | 1.37A | 3a50B-1n0wA:undetectable | 3a50B-1n0wA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o20 | GAMMA-GLUTAMYLPHOSPHATE REDUCTASE (Thermotogamaritima) |
PF00171(Aldedh) | 5 | THR A 292ILE A 275LEU A 261ILE A 316THR A 249 | None | 1.10A | 3a50B-1o20A:undetectable | 3a50B-1o20A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pe9 | PECTATE LYASE A (Dickeyachrysanthemi) |
PF00544(Pec_lyase_C) | 5 | MET A 210ILE A 189ASN A 285LEU A 187ILE A 198 | None | 1.37A | 3a50B-1pe9A:undetectable | 3a50B-1pe9A:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1poj | ISOASPARTYLDIPEPTIDASE (Escherichiacoli) |
PF01979(Amidohydro_1) | 5 | ILE A 223LEU A 209LEU A 216ILE A 212THR A 198 | None | 1.40A | 3a50B-1pojA:undetectable | 3a50B-1pojA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pxz | MAJOR POLLENALLERGEN JUN A 1 (Juniperus ashei) |
PF00544(Pec_lyase_C) | 5 | ILE A 92LEU A 168ASN A 220LEU A 108ILE A 123 | None | 1.32A | 3a50B-1pxzA:undetectable | 3a50B-1pxzA:23.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qlb | FUMARATE REDUCTASEIRON-SULFUR PROTEIN (Wolinellasuccinogenes) |
PF13085(Fer2_3)PF13183(Fer4_8) | 5 | MET B 34ILE B 38ASN B 70ILE B 28THR B 46 | None | 1.38A | 3a50B-1qlbB:undetectable | 3a50B-1qlbB:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s3d | ARSENATE REDUCTASE (Escherichiacoli) |
PF03960(ArsC) | 5 | ILE A 92LEU A 58ILE A 48THR A 103PRO A 39 | None | 1.17A | 3a50B-1s3dA:undetectable | 3a50B-1s3dA:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ua2 | CELL DIVISIONPROTEIN KINASE 7 (Homo sapiens) |
PF00069(Pkinase) | 5 | ILE A 114LEU A 143ASN A 73LEU A 203ILE A 202 | None | 1.13A | 3a50B-1ua2A:undetectable | 3a50B-1ua2A:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v5w | MEIOTICRECOMBINATIONPROTEIN DMC1/LIM15HOMOLOG (Homo sapiens) |
PF08423(Rad51) | 5 | ILE A 116LEU A 220LEU A 139ILE A 221THR A 267 | None | 1.33A | 3a50B-1v5wA:undetectable | 3a50B-1v5wA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vma | CELL DIVISIONPROTEIN FTSY (Thermotogamaritima) |
PF00448(SRP54)PF02881(SRP54_N) | 5 | ILE A 259LEU A 215ASN A 86LEU A 244THR A 103 | None | 1.18A | 3a50B-1vmaA:2.2 | 3a50B-1vmaA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wa5 | IMPORTIN ALPHASUBUNIT (Saccharomycescerevisiae) |
PF00514(Arm)PF01749(IBB)PF16186(Arm_3) | 5 | ILE B 365LEU B 424ASN B 454LEU B 388ILE B 385 | None | 1.13A | 3a50B-1wa5B:3.1 | 3a50B-1wa5B:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xp3 | ENDONUCLEASE IV (Bacillusanthracis) |
PF01261(AP_endonuc_2) | 5 | ILE A 238LEU A 214LEU A 243ILE A 216THR A 261 | None | 1.04A | 3a50B-1xp3A:undetectable | 3a50B-1xp3A:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xp8 | RECA PROTEIN (Deinococcusradiodurans) |
PF00154(RecA) | 5 | THR A 54ILE A 76LEU A 273LEU A 235ILE A 257 | None | 1.31A | 3a50B-1xp8A:undetectable | 3a50B-1xp8A:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aey | FRUCTAN1-EXOHYDROLASE IIA (Cichoriumintybus) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 5 | MET A 523ILE A 520LEU A 508LEU A 344ILE A 357 | None | 1.39A | 3a50B-2aeyA:undetectable | 3a50B-2aeyA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ani | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASEBETA SUBUNIT (Chlamydiatrachomatis) |
PF00268(Ribonuc_red_sm) | 5 | ILE A 100LEU A 20LEU A 185ILE A 241THR A 172 | None | 1.39A | 3a50B-2aniA:undetectable | 3a50B-2aniA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aqw | PUTATIVEOROTIDINE-MONOPHOSPHATE-DECARBOXYLASE (Plasmodiumyoelii) |
PF00215(OMPdecase) | 5 | ILE A 319ASN A 273LEU A 280ILE A 293THR A 16 | None | 1.37A | 3a50B-2aqwA:undetectable | 3a50B-2aqwA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bht | CYSTEINE SYNTHASE B (Escherichiacoli) |
PF00291(PALP) | 5 | ILE A 8LEU A 76LEU A 46ILE A 79PRO A 36 | None | 1.22A | 3a50B-2bhtA:undetectable | 3a50B-2bhtA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bmb | FOLIC ACID SYNTHESISPROTEIN FOL1 (Saccharomycescerevisiae) |
PF00809(Pterin_bind)PF01288(HPPK) | 5 | THR A 763ILE A 770ASN A 691LEU A 727PRO A 756 | None | 1.21A | 3a50B-2bmbA:undetectable | 3a50B-2bmbA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2esp | UBIQUITIN-CONJUGATING ENZYME E2 D2 (Homo sapiens) |
PF00179(UQ_con) | 5 | ILE A 99LEU A 86LEU A 103ILE A 106PRO A 65 | None | 1.13A | 3a50B-2espA:undetectable | 3a50B-2espA:16.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fv5 | ADAM 17 (Homo sapiens) |
PF13688(Reprolysin_5) | 5 | THR A 403LEU A 227ASN A 410LEU A 251ILE A 279 | None | 1.22A | 3a50B-2fv5A:undetectable | 3a50B-2fv5A:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hwx | TELOMERASE-BINDINGPROTEIN EST1A (Homo sapiens) |
PF13638(PIN_4) | 5 | LEU A1277ASN A1333LEU A1314ILE A1280PRO A1250 | None | 1.30A | 3a50B-2hwxA:undetectable | 3a50B-2hwxA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iwo | MULTIPLE PDZ DOMAINPROTEIN (Homo sapiens) |
PF00595(PDZ) | 5 | THR A1876MET A1837ILE A1912LEU A1845ILE A1847 | None | 1.26A | 3a50B-2iwoA:undetectable | 3a50B-2iwoA:17.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2np0 | BOTULINUM NEUROTOXINTYPE B (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07951(Toxin_R_bind_C)PF07952(Toxin_trans)PF07953(Toxin_R_bind_N) | 5 | ILE A 111ASN A 363LEU A 235ILE A 232THR A 171 | None | 1.20A | 3a50B-2np0A:2.7 | 3a50B-2np0A:15.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2okx | RHAMNOSIDASE B (Bacillus sp.GL1) |
PF05592(Bac_rhamnosid)PF08531(Bac_rhamnosid_N)PF17389(Bac_rhamnosid6H)PF17390(Bac_rhamnosid_C) | 5 | ILE A 653LEU A 661LEU A 712ILE A 634PRO A 605 | None | 1.25A | 3a50B-2okxA:undetectable | 3a50B-2okxA:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ve3 | PUTATIVE CYTOCHROMEP450 120 (Synechocystissp. PCC 6803) |
PF00067(p450) | 5 | ILE A 315LEU A 263MET A 401LEU A 269PRO A 430 | NoneNoneHEM A1444 ( 4.3A)NoneNone | 1.18A | 3a50B-2ve3A:32.7 | 3a50B-2ve3A:25.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xfb | E1 ENVELOPEGLYCOPROTEIN (Chikungunyavirus) |
PF01589(Alpha_E1_glycop) | 5 | ASN A 9LEU A 251ILE A 261THR A 263PRO A 40 | None | 1.36A | 3a50B-2xfbA:undetectable | 3a50B-2xfbA:20.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xkr | PUTATIVE CYTOCHROMEP450 142 (Mycobacteriumtuberculosis) |
PF00067(p450) | 5 | ILE A 76LEU A 159LEU A 226ILE A 229THR A 234 | HEM A1400 (-4.1A)NoneHEM A1400 (-4.4A)PG4 A1399 ( 4.5A)HEM A1400 (-3.7A) | 0.80A | 3a50B-2xkrA:45.0 | 3a50B-2xkrA:35.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xkr | PUTATIVE CYTOCHROMEP450 142 (Mycobacteriumtuberculosis) |
PF00067(p450) | 5 | MET A 74ILE A 76LEU A 159LEU A 226THR A 234 | PG4 A1399 ( 4.4A)HEM A1400 (-4.1A)NoneHEM A1400 (-4.4A)HEM A1400 (-3.7A) | 0.76A | 3a50B-2xkrA:45.0 | 3a50B-2xkrA:35.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yp1 | AROMATICPEROXYGENASE (Agrocybeaegerita) |
PF01328(Peroxidase_2) | 5 | THR A 78LEU A 48ASN A 61LEU A 115ILE A 95 | HEM A 350 (-4.2A)NoneNoneHEM A 350 ( 3.9A)None | 1.39A | 3a50B-2yp1A:undetectable | 3a50B-2yp1A:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zb3 | PROSTAGLANDINREDUCTASE 2 (Mus musculus) |
PF00107(ADH_zinc_N)PF16884(ADH_N_2) | 5 | ILE A 342LEU A 126LEU A 130ILE A 79THR A 43 | None | 1.35A | 3a50B-2zb3A:undetectable | 3a50B-2zb3A:22.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2zbz | CYTOCHROME P450-SU1 (Streptomycesgriseolus) |
PF00067(p450) | 5 | ILE A 96LEU A 180LEU A 240ILE A 243THR A 248 | HEM A 413 (-4.0A)VDX A 501 (-4.2A)HEM A 413 ( 4.5A)VDX A 501 (-4.2A)HEM A 413 (-3.2A) | 0.72A | 3a50B-2zbzA:47.6 | 3a50B-2zbzA:37.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aal | PROBABLEENDONUCLEASE 4 (Geobacilluskaustophilus) |
PF01261(AP_endonuc_2) | 5 | ILE A 237LEU A 213LEU A 242ILE A 215THR A 260 | None | 1.07A | 3a50B-3aalA:undetectable | 3a50B-3aalA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bzh | UBIQUITIN-CONJUGATING ENZYME E2 E1 (Homo sapiens) |
PF00179(UQ_con) | 5 | ILE A 145LEU A 132LEU A 149ILE A 152PRO A 111 | None | 1.02A | 3a50B-3bzhA:undetectable | 3a50B-3bzhA:16.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cgd | PYRIDINENUCLEOTIDE-DISULFIDEOXIDOREDUCTASE,CLASS I (Bacillusanthracis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | THR A 168MET A 165ILE A 161LEU A 239ILE A 141 | NoneNoneNAD A 818 (-3.8A)NoneNone | 1.30A | 3a50B-3cgdA:undetectable | 3a50B-3cgdA:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cue | TRANSPORT PROTEINPARTICLE 18 KDASUBUNITTRANSPORT PROTEINPARTICLE 23 KDASUBUNIT (Saccharomycescerevisiae) |
PF04099(Sybindin) | 5 | THR A 124ILE A 143LEU C 51LEU C 58ILE C 54 | None | 1.24A | 3a50B-3cueA:undetectable | 3a50B-3cueA:17.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ejb | BIOTIN BIOSYNTHESISCYTOCHROME P450-LIKEENZYME (Bacillussubtilis) |
PF00067(p450) | 6 | MET B 79LEU B 164ASN B 181LEU B 230ILE B 233THR B 238 | NoneNoneNoneHEM B 405 ( 4.6A)NoneHEM B 405 (-3.7A) | 0.85A | 3a50B-3ejbB:47.5 | 3a50B-3ejbB:36.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ejb | BIOTIN BIOSYNTHESISCYTOCHROME P450-LIKEENZYME (Bacillussubtilis) |
PF00067(p450) | 5 | MET B 79LEU B 164LEU B 230ILE B 233PRO B 61 | NoneNoneHEM B 405 ( 4.6A)NoneNone | 1.34A | 3a50B-3ejbB:47.5 | 3a50B-3ejbB:36.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fhn | PROTEIN TRANSPORTPROTEIN TIP20 (Saccharomycescerevisiae) |
PF04437(RINT1_TIP1) | 5 | ILE A 518LEU A 628ASN A 636LEU A 574ILE A 571 | None | 1.35A | 3a50B-3fhnA:undetectable | 3a50B-3fhnA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gae | PROTEIN DOA1 (Saccharomycescerevisiae) |
PF08324(PUL) | 5 | ILE A 483LEU A 502LEU A 509ILE A 505PRO A 535 | None | 1.38A | 3a50B-3gaeA:undetectable | 3a50B-3gaeA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3glv | LIPOPOLYSACCHARIDECORE BIOSYNTHESISPROTEIN (Thermoplasmavolcanium) |
PF01467(CTP_transf_like) | 5 | ILE A 88LEU A 108LEU A 101ILE A 105PRO A 85 | None | 1.27A | 3a50B-3glvA:undetectable | 3a50B-3glvA:15.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h5o | TRANSCRIPTIONALREGULATOR GNTR (Chromobacteriumviolaceum) |
PF13377(Peripla_BP_3) | 6 | THR A 133MET A 155ILE A 305LEU A 89ASN A 107ILE A 92 | NoneNoneNoneNoneSO4 A 1 (-3.2A)None | 1.30A | 3a50B-3h5oA:undetectable | 3a50B-3h5oA:25.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hn7 | UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE (Psychrobacterarcticus) |
PF01225(Mur_ligase)PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 5 | LEU A 349MET A 120LEU A 329ILE A 332THR A 312 | None | 1.24A | 3a50B-3hn7A:undetectable | 3a50B-3hn7A:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nic | ECO29KIR (Escherichiacoli) |
PF09517(RE_Eco29kI) | 5 | ILE A 105LEU A 101ILE A 129THR A 32PRO A 39 | None | 1.23A | 3a50B-3nicA:undetectable | 3a50B-3nicA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o8j | 2-METHYLCITRATESYNTHASE (Salmonellaenterica) |
PF00285(Citrate_synt) | 5 | MET A 110LEU A 345LEU A 143ILE A 348THR A 352 | None | 1.31A | 3a50B-3o8jA:1.4 | 3a50B-3o8jA:23.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rru | TOM1L1 PROTEIN (Homo sapiens) |
PF00790(VHS) | 5 | THR A 23ILE A 69LEU A 56LEU A 73ILE A 76 | None | 1.32A | 3a50B-3rruA:undetectable | 3a50B-3rruA:15.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s4w | FANCONI ANEMIA GROUPD2 PROTEIN HOMOLOG (Mus musculus) |
PF14631(FancD2) | 5 | LEU B 537ASN B 508MET B 505LEU B 495THR B 578 | None | 1.40A | 3a50B-3s4wB:2.7 | 3a50B-3s4wB:16.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sqn | CONSERVED DOMAINPROTEIN (Enterococcusfaecalis) |
PF05043(Mga) | 5 | LEU A 88ASN A 81LEU A 97ILE A 94THR A 10 | None | 1.19A | 3a50B-3sqnA:undetectable | 3a50B-3sqnA:23.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3thw | DNA MISMATCH REPAIRPROTEIN MSH3 (Homo sapiens) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05192(MutS_III) | 5 | THR B 928ILE B 528LEU B 902LEU B 533PRO B 574 | None | 1.28A | 3a50B-3thwB:undetectable | 3a50B-3thwB:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ulk | KETOL-ACIDREDUCTOISOMERASE (Escherichiacoli) |
PF01450(IlvC)PF07991(IlvN) | 5 | THR A 198MET A 56ILE A 63LEU A 105ILE A 103 | THR A 198 ( 0.8A)MET A 56 ( 0.0A)ILE A 63 ( 0.7A)LEU A 105 (-0.5A)ILE A 103 ( 0.7A) | 1.29A | 3a50B-3ulkA:undetectable | 3a50B-3ulkA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ure | ALPHA-LYTIC PROTEASE (Lysobacterenzymogenes) |
PF00089(Trypsin) | 5 | ILE A 210LEU A 180ASN A 101LEU A 199THR A 163 | None | 1.20A | 3a50B-3ureA:undetectable | 3a50B-3ureA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uwc | NUCLEOTIDE-SUGARAMINOTRANSFERASE (Coxiellaburnetii) |
PF01041(DegT_DnrJ_EryC1) | 5 | ILE A 196LEU A 186ASN A 238MET A 241ILE A 160 | None | 1.25A | 3a50B-3uwcA:undetectable | 3a50B-3uwcA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9i | MULTIDRUG RESISTANCEPROTEIN MEXB (Pseudomonasaeruginosa) |
PF00873(ACR_tran) | 5 | ILE A 310LEU A 137ASN A 298LEU A 166ILE A 291 | None | 1.32A | 3a50B-3w9iA:undetectable | 3a50B-3w9iA:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wwy | D-LACTATEDEHYDROGENASE (Fusobacteriumnucleatum) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | ILE A 255LYS A 121ASN A 123LEU A 232ILE A 231 | NoneGOL A 405 (-3.1A)NoneNoneNone | 1.31A | 3a50B-3wwyA:undetectable | 3a50B-3wwyA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zuq | BOTULINUM NEUROTOXINTYPE B (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07952(Toxin_trans) | 5 | ILE A 112ASN A 364LEU A 236ILE A 233THR A 172 | None | 1.19A | 3a50B-3zuqA:0.8 | 3a50B-3zuqA:16.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a26 | PUTATIVEC-1-TETRAHYDROFOLATESYNTHASE,CYTOPLASMIC (Leishmaniamajor) |
PF00763(THF_DHG_CYH)PF02882(THF_DHG_CYH_C) | 5 | MET A 161ILE A 211LEU A 182LEU A 154ILE A 151 | None | 1.41A | 3a50B-4a26A:undetectable | 3a50B-4a26A:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bwv | PHOSPHOADENOSINE-PHOSPHOSULPHATEREDUCTASE (Physcomitrellapatens) |
PF01507(PAPS_reduct) | 5 | ILE A 125LEU A 99LEU A 129ILE A 132THR A 105 | None | 1.39A | 3a50B-4bwvA:undetectable | 3a50B-4bwvA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c3s | ALDEHYDEDEHYDROGENASE (Lachnoclostridiumphytofermentans) |
PF00171(Aldedh) | 5 | ILE A 343LEU A 309ASN A 319LEU A 329ILE A 332 | None | 1.08A | 3a50B-4c3sA:undetectable | 3a50B-4c3sA:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c90 | ALPHA-GLUCURONIDASEGH115 (Bacteroidesovatus) |
PF15979(Glyco_hydro_115) | 5 | ILE A 76LEU A 86LEU A 72ILE A 55PRO A 52 | None | 1.40A | 3a50B-4c90A:undetectable | 3a50B-4c90A:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ddi | UBIQUITIN-CONJUGATING ENZYME E2 D2,UBIQUITINTHIOESTERASE OTUB1 (Homo sapiens) |
PF00179(UQ_con)PF10275(Peptidase_C65) | 5 | ILE A 99LEU A 86LEU A 103ILE A 106PRO A 65 | None | 1.05A | 3a50B-4ddiA:undetectable | 3a50B-4ddiA:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hiz | ENDOSIALIDASE (Enterobacteriaphage phi92) |
PF12217(End_beta_propel)PF12218(End_N_terminal)PF12219(End_tail_spike) | 5 | ILE A 309LEU A 278ASN A 229ILE A 276THR A 266 | None | 1.37A | 3a50B-4hizA:undetectable | 3a50B-4hizA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ii2 | UBIQUITIN-CONJUGATING ENZYME E2 4 (Schizosaccharomycespombe) |
PF00179(UQ_con) | 5 | ILE C 99LEU C 86LEU C 103ILE C 106PRO C 65 | None | 1.02A | 3a50B-4ii2C:undetectable | 3a50B-4ii2C:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ml9 | UNCHARACTERIZEDPROTEIN (Sebaldellatermitidis) |
PF00977(His_biosynth) | 5 | THR A 250ILE A 218LEU A 255ASN A 253ILE A 239 | NoneNoneNoneEDO A 309 (-3.3A)None | 1.28A | 3a50B-4ml9A:undetectable | 3a50B-4ml9A:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pv4 | PROLINEAMINOPEPTIDASE P II (Yersinia pestis) |
PF00557(Peptidase_M24)PF05195(AMP_N) | 5 | ILE A 295LEU A 379LEU A 299ILE A 408THR A 419 | None | 1.26A | 3a50B-4pv4A:undetectable | 3a50B-4pv4A:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q62 | LEUCINE-RICHREPEAT-AND COILEDCOIL-CONTAININGPROTEIN (Legionellapneumophila) |
PF13855(LRR_8) | 5 | LEU A 264ASN A 241LEU A 276ILE A 277THR A 301 | NoneNoneSO4 A 504 (-4.7A)NoneNone | 1.41A | 3a50B-4q62A:undetectable | 3a50B-4q62A:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q68 | UNCHARACTERIZEDPROTEIN (Bacteroidesuniformis) |
PF07313(DUF1460) | 5 | ILE A 117LEU A 71ASN A 92LEU A 258ILE A 198 | None | 1.40A | 3a50B-4q68A:undetectable | 3a50B-4q68A:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qrk | HYPOTHETICAL PROTEIN (Clostridiumsporogenes) |
PF09922(DUF2154)PF17115(Toast_rack_N) | 5 | ILE A 122LEU A 153LEU A 56ILE A 132THR A 52 | None | 1.34A | 3a50B-4qrkA:undetectable | 3a50B-4qrkA:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qtb | MITOGEN-ACTIVATEDPROTEIN KINASE 3 (Homo sapiens) |
PF00069(Pkinase) | 5 | ILE A 143LEU A 172ASN A 99LEU A 235ILE A 234 | NoneNoneEDO A 402 (-3.1A)NoneNone | 1.33A | 3a50B-4qtbA:undetectable | 3a50B-4qtbA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r1d | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
no annotation | 5 | THR A 556ILE A 189LEU A 155LEU A 194ILE A 158 | None | 1.38A | 3a50B-4r1dA:undetectable | 3a50B-4r1dA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r3u | 2-HYDROXYISOBUTYRYL-COA MUTASE LARGESUBUNIT (Aquincolatertiaricarbonis) |
PF01642(MM_CoA_mutase) | 5 | ILE A 168ASN A 527MET A 529LEU A 175ILE A 174 | None | 1.23A | 3a50B-4r3uA:undetectable | 3a50B-4r3uA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4re2 | BETA-MANNOSIDASE/BETA-GLUCOSIDASE (Oryza sativa) |
PF00232(Glyco_hydro_1) | 5 | ILE A 424LEU A 13LEU A 420ILE A 417PRO A 19 | None | 1.22A | 3a50B-4re2A:undetectable | 3a50B-4re2A:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzf | BAND 3 ANIONTRANSPORT PROTEIN (Homo sapiens) |
PF00955(HCO3_cotransp) | 5 | ILE A 864LEU A 687LEU A 680ILE A 684PRO A 868 | None | 1.32A | 3a50B-4yzfA:1.7 | 3a50B-4yzfA:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zg5 | 5'-NUCLEOTIDASE SURE (Brucellaabortus) |
no annotation | 5 | THR D 181ILE D 224LEU D 165ILE D 229THR D 140 | None | 1.16A | 3a50B-4zg5D:undetectable | 3a50B-4zg5D:25.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a22 | VESICULAR STOMATITISVIRUS L POLYMERASE (Vesicularstomatitisvirus) |
PF00946(Mononeg_RNA_pol)PF14314(Methyltrans_Mon)PF14318(Mononeg_mRNAcap) | 5 | THR A1741ILE A1774LEU A1667ASN A1725ILE A1759 | None | 1.38A | 3a50B-5a22A:undetectable | 3a50B-5a22A:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a8r | METHYL-COENZYME MREDUCTASE II SUBUNITGAMMA (Methanothermobactermarburgensis) |
PF02241(MCR_beta)PF02783(MCR_beta_N) | 5 | ILE B 217ASN B 250LEU B 241ILE B 27PRO B 428 | None | 1.38A | 3a50B-5a8rB:1.3 | 3a50B-5a8rB:24.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cj9 | ARGININE REPRESSOR (Bacillushalodurans) |
PF01316(Arg_repressor)PF02863(Arg_repressor_C) | 5 | THR A 40ILE A 45LEU A 29ASN A 35ILE A 10 | None | 1.32A | 3a50B-5cj9A:undetectable | 3a50B-5cj9A:15.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dzz | DESMOPLAKIN (Homo sapiens) |
PF00681(Plectin) | 5 | THR A2287ILE A2263LEU A2429ASN A2423ILE A2260 | None | 1.37A | 3a50B-5dzzA:undetectable | 3a50B-5dzzA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ey8 | ACYL-COA SYNTHASE (Mycolicibacteriumsmegmatis) |
PF00501(AMP-binding) | 5 | ILE A 103LEU A 204LEU A 184ILE A 199THR A 429 | None | 1.25A | 3a50B-5ey8A:undetectable | 3a50B-5ey8A:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fb8 | PRO-INTERLEUKIN-16 (Homo sapiens) |
PF00595(PDZ) | 5 | THR C 88MET C 90ILE C 82LEU C 105ILE C 102 | None | 1.27A | 3a50B-5fb8C:undetectable | 3a50B-5fb8C:14.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fg0 | E3 UBIQUITIN-PROTEINLIGASE LISTERIN (Saccharomycescerevisiae) |
no annotation | 5 | THR A 348ILE A 298LEU A 304LEU A 310THR A 258 | None | 1.34A | 3a50B-5fg0A:undetectable | 3a50B-5fg0A:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5z | ABC TRANSPORTER,SUBSTRATE-BINDINGPROTEIN (Streptococcuspneumoniae) |
PF01547(SBP_bac_1) | 5 | THR A 76LEU A 49ILE A 80THR A 53PRO A 427 | None | 1.36A | 3a50B-5g5zA:undetectable | 3a50B-5g5zA:19.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 7 | THR A 84MET A 86ILE A 88LEU A 232ILE A 235THR A 240PRO A 287 | NoneNoneHEM A 501 ( 4.4A)HEM A 501 ( 4.7A)NoneHEM A 501 (-3.7A)HEM A 501 (-3.5A) | 0.54A | 3a50B-5gnmA:56.5 | 3a50B-5gnmA:98.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hdt | SISTER CHROMATIDCOHESION PROTEINPDS5 HOMOLOG B (Homo sapiens) |
no annotation | 5 | ILE A 233LEU A 277ASN A 311LEU A 262ILE A 259 | None | 1.40A | 3a50B-5hdtA:undetectable | 3a50B-5hdtA:15.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hmp | UNCONVENTIONALMYOSIN-VC (Homo sapiens) |
PF00063(Myosin_head) | 5 | ILE A 666ASN A 456LEU A 670THR A 99PRO A 652 | None | 1.35A | 3a50B-5hmpA:undetectable | 3a50B-5hmpA:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iry | DESMOCOLLIN-1 (Homo sapiens) |
PF00028(Cadherin) | 5 | MET A 188ILE A 149LEU A 186ILE A 169THR A 172 | None | 1.40A | 3a50B-5iryA:undetectable | 3a50B-5iryA:20.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5l94 | CYTOCHROME P450 (Bacillusmegaterium) |
PF00067(p450) | 5 | ILE A 85LYS A 187LEU A 238ILE A 241THR A 246 | HEM A 501 (-4.4A)NoneHEM A 501 (-4.4A)TES A 502 (-4.0A)HEM A 501 (-3.4A) | 0.45A | 3a50B-5l94A:49.7 | 3a50B-5l94A:34.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lj9 | MACROLIDE EXPORTATP-BINDING/PERMEASEPROTEIN MACB (Escherichiacoli) |
no annotation | 5 | ILE A 214LEU A 24ASN A 52LEU A 29ILE A 27 | None | 1.36A | 3a50B-5lj9A:undetectable | 3a50B-5lj9A:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ubm | COMPLEMENT C1SSUBCOMPONENT (Homo sapiens) |
no annotation | 5 | THR A 678ILE A 510LEU A 471ASN A 466ILE A 530 | None | 1.28A | 3a50B-5ubmA:undetectable | 3a50B-5ubmA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uti | QUEUINETRNA-RIBOSYLTRANSFERASE (Zymomonasmobilis) |
no annotation | 5 | MET A 32ILE A 30LEU A 100ILE A 66PRO A 256 | None | 1.38A | 3a50B-5utiA:undetectable | 3a50B-5utiA:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xtd | NADH-UBIQUINONEOXIDOREDUCTASE CHAIN1 (Homo sapiens) |
PF15879(MWFE) | 5 | THR s 87ILE s 13LEU s 6LEU s 83PRO s 12 | None | 1.35A | 3a50B-5xtds:undetectable | 3a50B-5xtds:24.70 |