SIMILAR PATTERNS OF AMINO ACIDS FOR 3A50_B_VD3B2001

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bk6 KARYOPHERIN ALPHA

(Saccharomyces
cerevisiae)
PF00514
(Arm)
PF16186
(Arm_3)
5 ILE A 365
LEU A 424
ASN A 454
LEU A 388
ILE A 385
None
1.16A 3a50B-1bk6A:
3.1
3a50B-1bk6A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1buc BUTYRYL-COA
DEHYDROGENASE


(Megasphaera
elsdenii)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
5 THR A  51
LEU A 123
LEU A  45
ILE A  42
THR A 210
None
1.39A 3a50B-1bucA:
2.0
3a50B-1bucA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cby DELTA-ENDOTOXIN CYTB

(Bacillus
thuringiensis)
PF01338
(Bac_thur_toxin)
5 ILE A  87
LEU A  81
ASN A  76
LEU A 222
ILE A  92
None
1.26A 3a50B-1cbyA:
undetectable
3a50B-1cbyA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cqq TYPE 2 RHINOVIRUS 3C
PROTEASE


(Rhinovirus A)
PF00548
(Peptidase_C3)
5 ILE A 160
LEU A  70
ASN A 124
LEU A 174
PRO A  38
None
1.36A 3a50B-1cqqA:
undetectable
3a50B-1cqqA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1elv COMPLEMENT C1S
COMPONENT


(Homo sapiens)
PF00084
(Sushi)
PF00089
(Trypsin)
5 THR A 663
ILE A 495
LEU A 456
ASN A 451
ILE A 515
None
1.26A 3a50B-1elvA:
undetectable
3a50B-1elvA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1evj GLUCOSE-FRUCTOSE
OXIDOREDUCTASE


(Zymomonas
mobilis)
PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C)
5 MET A 290
ILE A 301
ASN A 220
LEU A 288
ILE A 171
None
1.23A 3a50B-1evjA:
undetectable
3a50B-1evjA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ


(Escherichia
virus G4)
PF02305
(Phage_F)
5 THR 1 406
MET 1 404
ILE 1  49
ASN 1 409
ILE 1  66
None
1.05A 3a50B-1gff1:
undetectable
3a50B-1gff1:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE


(Zymomonas
mobilis)
PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C)
5 MET A 342
ILE A 353
ASN A 272
LEU A 340
ILE A 223
None
1.17A 3a50B-1h6dA:
0.0
3a50B-1h6dA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k4y LIVER
CARBOXYLESTERASE


(Oryctolagus
cuniculus)
PF00135
(COesterase)
5 ILE A 334
ASN A 238
LEU A 232
THR A 320
PRO A 328
None
1.36A 3a50B-1k4yA:
0.0
3a50B-1k4yA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kr1 HEVAMINE A

(Hevea
brasiliensis)
PF00704
(Glyco_hydro_18)
5 ILE A  44
LEU A  16
ASN A  62
LEU A  76
ILE A  30
None
SO4  A 801 (-4.5A)
None
None
None
1.40A 3a50B-1kr1A:
undetectable
3a50B-1kr1A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lm7 SUBDOMAIN OF
DESMOPLAKIN
CARBOXY-TERMINAL
DOMAIN (DPCT)


(Homo sapiens)
PF00681
(Plectin)
5 THR A2287
ILE A2263
LEU A2429
ASN A2423
ILE A2260
None
1.37A 3a50B-1lm7A:
undetectable
3a50B-1lm7A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n0w DNA REPAIR PROTEIN
RAD51 HOMOLOG 1


(Homo sapiens)
PF08423
(Rad51)
5 ILE A 117
LEU A 219
LEU A 140
ILE A 220
THR A 266
None
1.37A 3a50B-1n0wA:
undetectable
3a50B-1n0wA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o20 GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE


(Thermotoga
maritima)
PF00171
(Aldedh)
5 THR A 292
ILE A 275
LEU A 261
ILE A 316
THR A 249
None
1.10A 3a50B-1o20A:
undetectable
3a50B-1o20A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pe9 PECTATE LYASE A

(Dickeya
chrysanthemi)
PF00544
(Pec_lyase_C)
5 MET A 210
ILE A 189
ASN A 285
LEU A 187
ILE A 198
None
1.37A 3a50B-1pe9A:
undetectable
3a50B-1pe9A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1poj ISOASPARTYL
DIPEPTIDASE


(Escherichia
coli)
PF01979
(Amidohydro_1)
5 ILE A 223
LEU A 209
LEU A 216
ILE A 212
THR A 198
None
1.40A 3a50B-1pojA:
undetectable
3a50B-1pojA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pxz MAJOR POLLEN
ALLERGEN JUN A 1


(Juniperus ashei)
PF00544
(Pec_lyase_C)
5 ILE A  92
LEU A 168
ASN A 220
LEU A 108
ILE A 123
None
1.32A 3a50B-1pxzA:
undetectable
3a50B-1pxzA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qlb FUMARATE REDUCTASE
IRON-SULFUR PROTEIN


(Wolinella
succinogenes)
PF13085
(Fer2_3)
PF13183
(Fer4_8)
5 MET B  34
ILE B  38
ASN B  70
ILE B  28
THR B  46
None
1.38A 3a50B-1qlbB:
undetectable
3a50B-1qlbB:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s3d ARSENATE REDUCTASE

(Escherichia
coli)
PF03960
(ArsC)
5 ILE A  92
LEU A  58
ILE A  48
THR A 103
PRO A  39
None
1.17A 3a50B-1s3dA:
undetectable
3a50B-1s3dA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ua2 CELL DIVISION
PROTEIN KINASE 7


(Homo sapiens)
PF00069
(Pkinase)
5 ILE A 114
LEU A 143
ASN A  73
LEU A 203
ILE A 202
None
1.13A 3a50B-1ua2A:
undetectable
3a50B-1ua2A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5w MEIOTIC
RECOMBINATION
PROTEIN DMC1/LIM15
HOMOLOG


(Homo sapiens)
PF08423
(Rad51)
5 ILE A 116
LEU A 220
LEU A 139
ILE A 221
THR A 267
None
1.33A 3a50B-1v5wA:
undetectable
3a50B-1v5wA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vma CELL DIVISION
PROTEIN FTSY


(Thermotoga
maritima)
PF00448
(SRP54)
PF02881
(SRP54_N)
5 ILE A 259
LEU A 215
ASN A  86
LEU A 244
THR A 103
None
1.18A 3a50B-1vmaA:
2.2
3a50B-1vmaA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wa5 IMPORTIN ALPHA
SUBUNIT


(Saccharomyces
cerevisiae)
PF00514
(Arm)
PF01749
(IBB)
PF16186
(Arm_3)
5 ILE B 365
LEU B 424
ASN B 454
LEU B 388
ILE B 385
None
1.13A 3a50B-1wa5B:
3.1
3a50B-1wa5B:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xp3 ENDONUCLEASE IV

(Bacillus
anthracis)
PF01261
(AP_endonuc_2)
5 ILE A 238
LEU A 214
LEU A 243
ILE A 216
THR A 261
None
1.04A 3a50B-1xp3A:
undetectable
3a50B-1xp3A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xp8 RECA PROTEIN

(Deinococcus
radiodurans)
PF00154
(RecA)
5 THR A  54
ILE A  76
LEU A 273
LEU A 235
ILE A 257
None
1.31A 3a50B-1xp8A:
undetectable
3a50B-1xp8A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aey FRUCTAN
1-EXOHYDROLASE IIA


(Cichorium
intybus)
PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C)
5 MET A 523
ILE A 520
LEU A 508
LEU A 344
ILE A 357
None
1.39A 3a50B-2aeyA:
undetectable
3a50B-2aeyA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ani RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA SUBUNIT


(Chlamydia
trachomatis)
PF00268
(Ribonuc_red_sm)
5 ILE A 100
LEU A  20
LEU A 185
ILE A 241
THR A 172
None
1.39A 3a50B-2aniA:
undetectable
3a50B-2aniA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aqw PUTATIVE
OROTIDINE-MONOPHOSPH
ATE-DECARBOXYLASE


(Plasmodium
yoelii)
PF00215
(OMPdecase)
5 ILE A 319
ASN A 273
LEU A 280
ILE A 293
THR A  16
None
1.37A 3a50B-2aqwA:
undetectable
3a50B-2aqwA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bht CYSTEINE SYNTHASE B

(Escherichia
coli)
PF00291
(PALP)
5 ILE A   8
LEU A  76
LEU A  46
ILE A  79
PRO A  36
None
1.22A 3a50B-2bhtA:
undetectable
3a50B-2bhtA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bmb FOLIC ACID SYNTHESIS
PROTEIN FOL1


(Saccharomyces
cerevisiae)
PF00809
(Pterin_bind)
PF01288
(HPPK)
5 THR A 763
ILE A 770
ASN A 691
LEU A 727
PRO A 756
None
1.21A 3a50B-2bmbA:
undetectable
3a50B-2bmbA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2esp UBIQUITIN-CONJUGATIN
G ENZYME E2 D2


(Homo sapiens)
PF00179
(UQ_con)
5 ILE A  99
LEU A  86
LEU A 103
ILE A 106
PRO A  65
None
1.13A 3a50B-2espA:
undetectable
3a50B-2espA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fv5 ADAM 17

(Homo sapiens)
PF13688
(Reprolysin_5)
5 THR A 403
LEU A 227
ASN A 410
LEU A 251
ILE A 279
None
1.22A 3a50B-2fv5A:
undetectable
3a50B-2fv5A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hwx TELOMERASE-BINDING
PROTEIN EST1A


(Homo sapiens)
PF13638
(PIN_4)
5 LEU A1277
ASN A1333
LEU A1314
ILE A1280
PRO A1250
None
1.30A 3a50B-2hwxA:
undetectable
3a50B-2hwxA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iwo MULTIPLE PDZ DOMAIN
PROTEIN


(Homo sapiens)
PF00595
(PDZ)
5 THR A1876
MET A1837
ILE A1912
LEU A1845
ILE A1847
None
1.26A 3a50B-2iwoA:
undetectable
3a50B-2iwoA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2np0 BOTULINUM NEUROTOXIN
TYPE B


(Clostridium
botulinum)
PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N)
5 ILE A 111
ASN A 363
LEU A 235
ILE A 232
THR A 171
None
1.20A 3a50B-2np0A:
2.7
3a50B-2np0A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okx RHAMNOSIDASE B

(Bacillus sp.
GL1)
PF05592
(Bac_rhamnosid)
PF08531
(Bac_rhamnosid_N)
PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C)
5 ILE A 653
LEU A 661
LEU A 712
ILE A 634
PRO A 605
None
1.25A 3a50B-2okxA:
undetectable
3a50B-2okxA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ve3 PUTATIVE CYTOCHROME
P450 120


(Synechocystis
sp. PCC 6803)
PF00067
(p450)
5 ILE A 315
LEU A 263
MET A 401
LEU A 269
PRO A 430
None
None
HEM  A1444 ( 4.3A)
None
None
1.18A 3a50B-2ve3A:
32.7
3a50B-2ve3A:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xfb E1 ENVELOPE
GLYCOPROTEIN


(Chikungunya
virus)
PF01589
(Alpha_E1_glycop)
5 ASN A   9
LEU A 251
ILE A 261
THR A 263
PRO A  40
None
1.36A 3a50B-2xfbA:
undetectable
3a50B-2xfbA:
20.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2xkr PUTATIVE CYTOCHROME
P450 142


(Mycobacterium
tuberculosis)
PF00067
(p450)
5 ILE A  76
LEU A 159
LEU A 226
ILE A 229
THR A 234
HEM  A1400 (-4.1A)
None
HEM  A1400 (-4.4A)
PG4  A1399 ( 4.5A)
HEM  A1400 (-3.7A)
0.80A 3a50B-2xkrA:
45.0
3a50B-2xkrA:
35.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2xkr PUTATIVE CYTOCHROME
P450 142


(Mycobacterium
tuberculosis)
PF00067
(p450)
5 MET A  74
ILE A  76
LEU A 159
LEU A 226
THR A 234
PG4  A1399 ( 4.4A)
HEM  A1400 (-4.1A)
None
HEM  A1400 (-4.4A)
HEM  A1400 (-3.7A)
0.76A 3a50B-2xkrA:
45.0
3a50B-2xkrA:
35.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yp1 AROMATIC
PEROXYGENASE


(Agrocybe
aegerita)
PF01328
(Peroxidase_2)
5 THR A  78
LEU A  48
ASN A  61
LEU A 115
ILE A  95
HEM  A 350 (-4.2A)
None
None
HEM  A 350 ( 3.9A)
None
1.39A 3a50B-2yp1A:
undetectable
3a50B-2yp1A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zb3 PROSTAGLANDIN
REDUCTASE 2


(Mus musculus)
PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2)
5 ILE A 342
LEU A 126
LEU A 130
ILE A  79
THR A  43
None
1.35A 3a50B-2zb3A:
undetectable
3a50B-2zb3A:
22.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zbz CYTOCHROME P450-SU1

(Streptomyces
griseolus)
PF00067
(p450)
5 ILE A  96
LEU A 180
LEU A 240
ILE A 243
THR A 248
HEM  A 413 (-4.0A)
VDX  A 501 (-4.2A)
HEM  A 413 ( 4.5A)
VDX  A 501 (-4.2A)
HEM  A 413 (-3.2A)
0.72A 3a50B-2zbzA:
47.6
3a50B-2zbzA:
37.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aal PROBABLE
ENDONUCLEASE 4


(Geobacillus
kaustophilus)
PF01261
(AP_endonuc_2)
5 ILE A 237
LEU A 213
LEU A 242
ILE A 215
THR A 260
None
1.07A 3a50B-3aalA:
undetectable
3a50B-3aalA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bzh UBIQUITIN-CONJUGATIN
G ENZYME E2 E1


(Homo sapiens)
PF00179
(UQ_con)
5 ILE A 145
LEU A 132
LEU A 149
ILE A 152
PRO A 111
None
1.02A 3a50B-3bzhA:
undetectable
3a50B-3bzhA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cgd PYRIDINE
NUCLEOTIDE-DISULFIDE
OXIDOREDUCTASE,
CLASS I


(Bacillus
anthracis)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
5 THR A 168
MET A 165
ILE A 161
LEU A 239
ILE A 141
None
None
NAD  A 818 (-3.8A)
None
None
1.30A 3a50B-3cgdA:
undetectable
3a50B-3cgdA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cue TRANSPORT PROTEIN
PARTICLE 18 KDA
SUBUNIT
TRANSPORT PROTEIN
PARTICLE 23 KDA
SUBUNIT


(Saccharomyces
cerevisiae)
PF04099
(Sybindin)
5 THR A 124
ILE A 143
LEU C  51
LEU C  58
ILE C  54
None
1.24A 3a50B-3cueA:
undetectable
3a50B-3cueA:
17.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ejb BIOTIN BIOSYNTHESIS
CYTOCHROME P450-LIKE
ENZYME


(Bacillus
subtilis)
PF00067
(p450)
6 MET B  79
LEU B 164
ASN B 181
LEU B 230
ILE B 233
THR B 238
None
None
None
HEM  B 405 ( 4.6A)
None
HEM  B 405 (-3.7A)
0.85A 3a50B-3ejbB:
47.5
3a50B-3ejbB:
36.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ejb BIOTIN BIOSYNTHESIS
CYTOCHROME P450-LIKE
ENZYME


(Bacillus
subtilis)
PF00067
(p450)
5 MET B  79
LEU B 164
LEU B 230
ILE B 233
PRO B  61
None
None
HEM  B 405 ( 4.6A)
None
None
1.34A 3a50B-3ejbB:
47.5
3a50B-3ejbB:
36.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhn PROTEIN TRANSPORT
PROTEIN TIP20


(Saccharomyces
cerevisiae)
PF04437
(RINT1_TIP1)
5 ILE A 518
LEU A 628
ASN A 636
LEU A 574
ILE A 571
None
1.35A 3a50B-3fhnA:
undetectable
3a50B-3fhnA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gae PROTEIN DOA1

(Saccharomyces
cerevisiae)
PF08324
(PUL)
5 ILE A 483
LEU A 502
LEU A 509
ILE A 505
PRO A 535
None
1.38A 3a50B-3gaeA:
undetectable
3a50B-3gaeA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3glv LIPOPOLYSACCHARIDE
CORE BIOSYNTHESIS
PROTEIN


(Thermoplasma
volcanium)
PF01467
(CTP_transf_like)
5 ILE A  88
LEU A 108
LEU A 101
ILE A 105
PRO A  85
None
1.27A 3a50B-3glvA:
undetectable
3a50B-3glvA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h5o TRANSCRIPTIONAL
REGULATOR GNTR


(Chromobacterium
violaceum)
PF13377
(Peripla_BP_3)
6 THR A 133
MET A 155
ILE A 305
LEU A  89
ASN A 107
ILE A  92
None
None
None
None
SO4  A   1 (-3.2A)
None
1.30A 3a50B-3h5oA:
undetectable
3a50B-3h5oA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hn7 UDP-N-ACETYLMURAMATE
-L-ALANINE LIGASE


(Psychrobacter
arcticus)
PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M)
5 LEU A 349
MET A 120
LEU A 329
ILE A 332
THR A 312
None
1.24A 3a50B-3hn7A:
undetectable
3a50B-3hn7A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nic ECO29KIR

(Escherichia
coli)
PF09517
(RE_Eco29kI)
5 ILE A 105
LEU A 101
ILE A 129
THR A  32
PRO A  39
None
1.23A 3a50B-3nicA:
undetectable
3a50B-3nicA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8j 2-METHYLCITRATE
SYNTHASE


(Salmonella
enterica)
PF00285
(Citrate_synt)
5 MET A 110
LEU A 345
LEU A 143
ILE A 348
THR A 352
None
1.31A 3a50B-3o8jA:
1.4
3a50B-3o8jA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rru TOM1L1 PROTEIN

(Homo sapiens)
PF00790
(VHS)
5 THR A  23
ILE A  69
LEU A  56
LEU A  73
ILE A  76
None
1.32A 3a50B-3rruA:
undetectable
3a50B-3rruA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s4w FANCONI ANEMIA GROUP
D2 PROTEIN HOMOLOG


(Mus musculus)
PF14631
(FancD2)
5 LEU B 537
ASN B 508
MET B 505
LEU B 495
THR B 578
None
1.40A 3a50B-3s4wB:
2.7
3a50B-3s4wB:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqn CONSERVED DOMAIN
PROTEIN


(Enterococcus
faecalis)
PF05043
(Mga)
5 LEU A  88
ASN A  81
LEU A  97
ILE A  94
THR A  10
None
1.19A 3a50B-3sqnA:
undetectable
3a50B-3sqnA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3thw DNA MISMATCH REPAIR
PROTEIN MSH3


(Homo sapiens)
PF00488
(MutS_V)
PF01624
(MutS_I)
PF05188
(MutS_II)
PF05192
(MutS_III)
5 THR B 928
ILE B 528
LEU B 902
LEU B 533
PRO B 574
None
1.28A 3a50B-3thwB:
undetectable
3a50B-3thwB:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ulk KETOL-ACID
REDUCTOISOMERASE


(Escherichia
coli)
PF01450
(IlvC)
PF07991
(IlvN)
5 THR A 198
MET A  56
ILE A  63
LEU A 105
ILE A 103
THR  A 198 ( 0.8A)
MET  A  56 ( 0.0A)
ILE  A  63 ( 0.7A)
LEU  A 105 (-0.5A)
ILE  A 103 ( 0.7A)
1.29A 3a50B-3ulkA:
undetectable
3a50B-3ulkA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ure ALPHA-LYTIC PROTEASE

(Lysobacter
enzymogenes)
PF00089
(Trypsin)
5 ILE A 210
LEU A 180
ASN A 101
LEU A 199
THR A 163
None
1.20A 3a50B-3ureA:
undetectable
3a50B-3ureA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uwc NUCLEOTIDE-SUGAR
AMINOTRANSFERASE


(Coxiella
burnetii)
PF01041
(DegT_DnrJ_EryC1)
5 ILE A 196
LEU A 186
ASN A 238
MET A 241
ILE A 160
None
1.25A 3a50B-3uwcA:
undetectable
3a50B-3uwcA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w9i MULTIDRUG RESISTANCE
PROTEIN MEXB


(Pseudomonas
aeruginosa)
PF00873
(ACR_tran)
5 ILE A 310
LEU A 137
ASN A 298
LEU A 166
ILE A 291
None
1.32A 3a50B-3w9iA:
undetectable
3a50B-3w9iA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wwy D-LACTATE
DEHYDROGENASE


(Fusobacterium
nucleatum)
PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
5 ILE A 255
LYS A 121
ASN A 123
LEU A 232
ILE A 231
None
GOL  A 405 (-3.1A)
None
None
None
1.31A 3a50B-3wwyA:
undetectable
3a50B-3wwyA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zuq BOTULINUM NEUROTOXIN
TYPE B


(Clostridium
botulinum)
PF01742
(Peptidase_M27)
PF07952
(Toxin_trans)
5 ILE A 112
ASN A 364
LEU A 236
ILE A 233
THR A 172
None
1.19A 3a50B-3zuqA:
0.8
3a50B-3zuqA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a26 PUTATIVE
C-1-TETRAHYDROFOLATE
SYNTHASE,
CYTOPLASMIC


(Leishmania
major)
PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C)
5 MET A 161
ILE A 211
LEU A 182
LEU A 154
ILE A 151
None
1.41A 3a50B-4a26A:
undetectable
3a50B-4a26A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bwv PHOSPHOADENOSINE-PHO
SPHOSULPHATE
REDUCTASE


(Physcomitrella
patens)
PF01507
(PAPS_reduct)
5 ILE A 125
LEU A  99
LEU A 129
ILE A 132
THR A 105
None
1.39A 3a50B-4bwvA:
undetectable
3a50B-4bwvA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3s ALDEHYDE
DEHYDROGENASE


(Lachnoclostridium
phytofermentans)
PF00171
(Aldedh)
5 ILE A 343
LEU A 309
ASN A 319
LEU A 329
ILE A 332
None
1.08A 3a50B-4c3sA:
undetectable
3a50B-4c3sA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c90 ALPHA-GLUCURONIDASE
GH115


(Bacteroides
ovatus)
PF15979
(Glyco_hydro_115)
5 ILE A  76
LEU A  86
LEU A  72
ILE A  55
PRO A  52
None
1.40A 3a50B-4c90A:
undetectable
3a50B-4c90A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ddi UBIQUITIN-CONJUGATIN
G ENZYME E2 D2,
UBIQUITIN
THIOESTERASE OTUB1


(Homo sapiens)
PF00179
(UQ_con)
PF10275
(Peptidase_C65)
5 ILE A  99
LEU A  86
LEU A 103
ILE A 106
PRO A  65
None
1.05A 3a50B-4ddiA:
undetectable
3a50B-4ddiA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hiz ENDOSIALIDASE

(Enterobacteria
phage phi92)
PF12217
(End_beta_propel)
PF12218
(End_N_terminal)
PF12219
(End_tail_spike)
5 ILE A 309
LEU A 278
ASN A 229
ILE A 276
THR A 266
None
1.37A 3a50B-4hizA:
undetectable
3a50B-4hizA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ii2 UBIQUITIN-CONJUGATIN
G ENZYME E2 4


(Schizosaccharomyces
pombe)
PF00179
(UQ_con)
5 ILE C  99
LEU C  86
LEU C 103
ILE C 106
PRO C  65
None
1.02A 3a50B-4ii2C:
undetectable
3a50B-4ii2C:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ml9 UNCHARACTERIZED
PROTEIN


(Sebaldella
termitidis)
PF00977
(His_biosynth)
5 THR A 250
ILE A 218
LEU A 255
ASN A 253
ILE A 239
None
None
None
EDO  A 309 (-3.3A)
None
1.28A 3a50B-4ml9A:
undetectable
3a50B-4ml9A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pv4 PROLINE
AMINOPEPTIDASE P II


(Yersinia pestis)
PF00557
(Peptidase_M24)
PF05195
(AMP_N)
5 ILE A 295
LEU A 379
LEU A 299
ILE A 408
THR A 419
None
1.26A 3a50B-4pv4A:
undetectable
3a50B-4pv4A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q62 LEUCINE-RICH
REPEAT-AND COILED
COIL-CONTAINING
PROTEIN


(Legionella
pneumophila)
PF13855
(LRR_8)
5 LEU A 264
ASN A 241
LEU A 276
ILE A 277
THR A 301
None
None
SO4  A 504 (-4.7A)
None
None
1.41A 3a50B-4q62A:
undetectable
3a50B-4q62A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q68 UNCHARACTERIZED
PROTEIN


(Bacteroides
uniformis)
PF07313
(DUF1460)
5 ILE A 117
LEU A  71
ASN A  92
LEU A 258
ILE A 198
None
1.40A 3a50B-4q68A:
undetectable
3a50B-4q68A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qrk HYPOTHETICAL PROTEIN

(Clostridium
sporogenes)
PF09922
(DUF2154)
PF17115
(Toast_rack_N)
5 ILE A 122
LEU A 153
LEU A  56
ILE A 132
THR A  52
None
1.34A 3a50B-4qrkA:
undetectable
3a50B-4qrkA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qtb MITOGEN-ACTIVATED
PROTEIN KINASE 3


(Homo sapiens)
PF00069
(Pkinase)
5 ILE A 143
LEU A 172
ASN A  99
LEU A 235
ILE A 234
None
None
EDO  A 402 (-3.1A)
None
None
1.33A 3a50B-4qtbA:
undetectable
3a50B-4qtbA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r1d UNCHARACTERIZED
PROTEIN


(Pseudomonas
aeruginosa)
no annotation 5 THR A 556
ILE A 189
LEU A 155
LEU A 194
ILE A 158
None
1.38A 3a50B-4r1dA:
undetectable
3a50B-4r1dA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r3u 2-HYDROXYISOBUTYRYL-
COA MUTASE LARGE
SUBUNIT


(Aquincola
tertiaricarbonis)
PF01642
(MM_CoA_mutase)
5 ILE A 168
ASN A 527
MET A 529
LEU A 175
ILE A 174
None
1.23A 3a50B-4r3uA:
undetectable
3a50B-4r3uA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4re2 BETA-MANNOSIDASE/BET
A-GLUCOSIDASE


(Oryza sativa)
PF00232
(Glyco_hydro_1)
5 ILE A 424
LEU A  13
LEU A 420
ILE A 417
PRO A  19
None
1.22A 3a50B-4re2A:
undetectable
3a50B-4re2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yzf BAND 3 ANION
TRANSPORT PROTEIN


(Homo sapiens)
PF00955
(HCO3_cotransp)
5 ILE A 864
LEU A 687
LEU A 680
ILE A 684
PRO A 868
None
1.32A 3a50B-4yzfA:
1.7
3a50B-4yzfA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zg5 5'-NUCLEOTIDASE SURE

(Brucella
abortus)
no annotation 5 THR D 181
ILE D 224
LEU D 165
ILE D 229
THR D 140
None
1.16A 3a50B-4zg5D:
undetectable
3a50B-4zg5D:
25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a22 VESICULAR STOMATITIS
VIRUS L POLYMERASE


(Vesicular
stomatitis
virus)
PF00946
(Mononeg_RNA_pol)
PF14314
(Methyltrans_Mon)
PF14318
(Mononeg_mRNAcap)
5 THR A1741
ILE A1774
LEU A1667
ASN A1725
ILE A1759
None
1.38A 3a50B-5a22A:
undetectable
3a50B-5a22A:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a8r METHYL-COENZYME M
REDUCTASE II SUBUNIT
GAMMA


(Methanothermobacter
marburgensis)
PF02241
(MCR_beta)
PF02783
(MCR_beta_N)
5 ILE B 217
ASN B 250
LEU B 241
ILE B  27
PRO B 428
None
1.38A 3a50B-5a8rB:
1.3
3a50B-5a8rB:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cj9 ARGININE REPRESSOR

(Bacillus
halodurans)
PF01316
(Arg_repressor)
PF02863
(Arg_repressor_C)
5 THR A  40
ILE A  45
LEU A  29
ASN A  35
ILE A  10
None
1.32A 3a50B-5cj9A:
undetectable
3a50B-5cj9A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzz DESMOPLAKIN

(Homo sapiens)
PF00681
(Plectin)
5 THR A2287
ILE A2263
LEU A2429
ASN A2423
ILE A2260
None
1.37A 3a50B-5dzzA:
undetectable
3a50B-5dzzA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ey8 ACYL-COA SYNTHASE

(Mycolicibacterium
smegmatis)
PF00501
(AMP-binding)
5 ILE A 103
LEU A 204
LEU A 184
ILE A 199
THR A 429
None
1.25A 3a50B-5ey8A:
undetectable
3a50B-5ey8A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fb8 PRO-INTERLEUKIN-16

(Homo sapiens)
PF00595
(PDZ)
5 THR C  88
MET C  90
ILE C  82
LEU C 105
ILE C 102
None
1.27A 3a50B-5fb8C:
undetectable
3a50B-5fb8C:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fg0 E3 UBIQUITIN-PROTEIN
LIGASE LISTERIN


(Saccharomyces
cerevisiae)
no annotation 5 THR A 348
ILE A 298
LEU A 304
LEU A 310
THR A 258
None
1.34A 3a50B-5fg0A:
undetectable
3a50B-5fg0A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5z ABC TRANSPORTER,
SUBSTRATE-BINDING
PROTEIN


(Streptococcus
pneumoniae)
PF01547
(SBP_bac_1)
5 THR A  76
LEU A  49
ILE A  80
THR A  53
PRO A 427
None
1.36A 3a50B-5g5zA:
undetectable
3a50B-5g5zA:
19.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5gnm VITAMIN D(3)
25-HYDROXYLASE


(Pseudonocardia
autotrophica)
PF00067
(p450)
7 THR A  84
MET A  86
ILE A  88
LEU A 232
ILE A 235
THR A 240
PRO A 287
None
None
HEM  A 501 ( 4.4A)
HEM  A 501 ( 4.7A)
None
HEM  A 501 (-3.7A)
HEM  A 501 (-3.5A)
0.54A 3a50B-5gnmA:
56.5
3a50B-5gnmA:
98.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hdt SISTER CHROMATID
COHESION PROTEIN
PDS5 HOMOLOG B


(Homo sapiens)
no annotation 5 ILE A 233
LEU A 277
ASN A 311
LEU A 262
ILE A 259
None
1.40A 3a50B-5hdtA:
undetectable
3a50B-5hdtA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hmp UNCONVENTIONAL
MYOSIN-VC


(Homo sapiens)
PF00063
(Myosin_head)
5 ILE A 666
ASN A 456
LEU A 670
THR A  99
PRO A 652
None
1.35A 3a50B-5hmpA:
undetectable
3a50B-5hmpA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iry DESMOCOLLIN-1

(Homo sapiens)
PF00028
(Cadherin)
5 MET A 188
ILE A 149
LEU A 186
ILE A 169
THR A 172
None
1.40A 3a50B-5iryA:
undetectable
3a50B-5iryA:
20.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5l94 CYTOCHROME P450

(Bacillus
megaterium)
PF00067
(p450)
5 ILE A  85
LYS A 187
LEU A 238
ILE A 241
THR A 246
HEM  A 501 (-4.4A)
None
HEM  A 501 (-4.4A)
TES  A 502 (-4.0A)
HEM  A 501 (-3.4A)
0.45A 3a50B-5l94A:
49.7
3a50B-5l94A:
34.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lj9 MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB


(Escherichia
coli)
no annotation 5 ILE A 214
LEU A  24
ASN A  52
LEU A  29
ILE A  27
None
1.36A 3a50B-5lj9A:
undetectable
3a50B-5lj9A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ubm COMPLEMENT C1S
SUBCOMPONENT


(Homo sapiens)
no annotation 5 THR A 678
ILE A 510
LEU A 471
ASN A 466
ILE A 530
None
1.28A 3a50B-5ubmA:
undetectable
3a50B-5ubmA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE


(Zymomonas
mobilis)
no annotation 5 MET A  32
ILE A  30
LEU A 100
ILE A  66
PRO A 256
None
1.38A 3a50B-5utiA:
undetectable
3a50B-5utiA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xtd NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1


(Homo sapiens)
PF15879
(MWFE)
5 THR s  87
ILE s  13
LEU s   6
LEU s  83
PRO s  12
None
1.35A 3a50B-5xtds:
undetectable
3a50B-5xtds:
24.70