SIMILAR PATTERNS OF AMINO ACIDS FOR 3A2Q_A_ACAA601_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6z | CHITINASE B (Serratiamarcescens) |
PF00704(Glyco_hydro_18) | 4 | GLY A 9ASN A 48ALA A 6VAL A 286 | None | 0.77A | 3a2qA-1e6zA:0.0 | 3a2qA-1e6zA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hwn | EBULIN (Sambucus ebulus) |
PF00161(RIP) | 4 | ASN A 100ALA A 70ALA A 80ILE A 1 | None | 0.81A | 3a2qA-1hwnA:0.0 | 3a2qA-1hwnA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1npc | NEUTRAL PROTEASE (Bacillus cereus) |
PF01447(Peptidase_M4)PF02868(Peptidase_M4_C) | 4 | ASN A 272ALA A 289ALA A 292ILE A 169 | None | 0.80A | 3a2qA-1npcA:undetectable | 3a2qA-1npcA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o8c | YHDH (Escherichiacoli) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLY A 62ALA A 102ALA A 99VAL A 104 | None | 0.73A | 3a2qA-1o8cA:undetectable | 3a2qA-1o8cA:24.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sq7 | TRIOSEPHOSPHATEISOMERASE (Gallus gallus) |
PF00121(TIM) | 4 | GLY A 210ALA A 181ALA A 176VAL A 226 | None | 0.79A | 3a2qA-1sq7A:0.3 | 3a2qA-1sq7A:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1un9 | DIHYDROXYACETONEKINASE (Citrobacterfreundii) |
PF02733(Dak1)PF02734(Dak2) | 4 | GLY A 302ALA A 213VAL A 236ILE A 272 | None | 0.69A | 3a2qA-1un9A:0.0 | 3a2qA-1un9A:24.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vhk | HYPOTHETICAL PROTEINYQEU (Bacillussubtilis) |
PF04452(Methyltrans_RNA) | 4 | GLY A 100ALA A 136ALA A 139VAL A 151 | None | 0.75A | 3a2qA-1vhkA:0.0 | 3a2qA-1vhkA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wdw | TRYPTOPHAN SYNTHASEBETA CHAIN 1 (Pyrococcusfuriosus) |
PF00291(PALP) | 4 | SER B 346ALA B 343VAL B 76ILE B 203 | PLP B 400 ( 4.1A)PLP B 400 ( 3.8A)NoneNone | 0.76A | 3a2qA-1wdwB:0.0 | 3a2qA-1wdwB:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xaj | 3-DEHYDROQUINATESYNTHASE (Staphylococcusaureus) |
PF01761(DHQ_synthase) | 4 | GLY A 103ALA A 128VAL A 42ILE A 64 | NoneNAD A 400 ( 4.5A)NAD A 400 (-4.4A)None | 0.75A | 3a2qA-1xajA:0.2 | 3a2qA-1xajA:23.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y81 | CONSERVEDHYPOTHETICAL PROTEIN (Pyrococcusfuriosus) |
PF13380(CoA_binding_2) | 4 | GLY A 22ASN A 23VAL A 36ILE A 46 | NoneNoneUNX A 406 ( 4.2A)None | 0.66A | 3a2qA-1y81A:undetectable | 3a2qA-1y81A:14.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b61 | HOMOSERINEO-ACETYLTRANSFERASE (Haemophilusinfluenzae) |
PF00561(Abhydrolase_1) | 4 | GLY A 96SER A 99VAL A 123ILE A 115 | None | 0.71A | 3a2qA-2b61A:undetectable | 3a2qA-2b61A:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d90 | PDZ DOMAINCONTAINING PROTEIN 1 (Mus musculus) |
PF00595(PDZ) | 5 | GLY A 20SER A 41ALA A 46VAL A 10ILE A 34 | None | 1.15A | 3a2qA-2d90A:undetectable | 3a2qA-2d90A:14.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dby | GTP-BINDING PROTEIN (Thermusthermophilus) |
PF01926(MMR_HSR1)PF06071(YchF-GTPase_C) | 4 | GLY A 278ALA A 104ALA A 102VAL A 207 | None | 0.73A | 3a2qA-2dbyA:undetectable | 3a2qA-2dbyA:23.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gko | SUBTILISINMICROBIAL SERINEPROTEINASES (Bacillussubtilis) |
PF00082(Peptidase_S8) | 4 | GLY A 209ALA A 189ALA A 187VAL A 202 | NoneNone NA A 614 ( 4.1A)None | 0.81A | 3a2qA-2gkoA:undetectable | 3a2qA-2gkoA:25.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h9f | HYPOTHETICAL PROTEIN (Pseudomonasaeruginosa) |
PF04303(PrpF) | 4 | GLY A 21ALA A 11VAL A 388ILE A 48 | None | 0.81A | 3a2qA-2h9fA:undetectable | 3a2qA-2h9fA:24.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h9f | HYPOTHETICAL PROTEIN (Pseudomonasaeruginosa) |
PF04303(PrpF) | 4 | GLY A 110ALA A 115VAL A 134ILE A 174 | None | 0.75A | 3a2qA-2h9fA:undetectable | 3a2qA-2h9fA:24.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ii1 | ACETAMIDASE (Bacillushalodurans) |
PF03069(FmdA_AmdA) | 5 | GLY A 135ALA A 175ALA A 137VAL A 65ILE A 76 | None | 1.15A | 3a2qA-2ii1A:undetectable | 3a2qA-2ii1A:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2it2 | UPF0130 PROTEINPH1069 (Pyrococcushorikoshii) |
PF02676(TYW3) | 4 | GLY A 111ALA A 18ALA A 14ILE A 42 | None | 0.76A | 3a2qA-2it2A:undetectable | 3a2qA-2it2A:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kc7 | BFR218_PROTEIN (Bacteroidesfragilis) |
PF00515(TPR_1) | 4 | GLY A 42ASN A 43ALA A 61ILE A 11 | None | 0.77A | 3a2qA-2kc7A:undetectable | 3a2qA-2kc7A:11.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2phc | UNCHARACTERIZEDPROTEIN PH0987 (Pyrococcushorikoshii) |
PF02682(CT_C_D) | 4 | ALA B 135ALA B 172VAL B 125ILE B 86 | None | 0.75A | 3a2qA-2phcB:undetectable | 3a2qA-2phcB:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pnn | TRANSIENT RECEPTORPOTENTIAL CATIONCHANNEL SUBFAMILY VMEMBER 1 (Rattusnorvegicus) |
PF12796(Ank_2) | 4 | SER A 343ALA A 295VAL A 305ILE A 352 | SER A 343 ( 0.0A)ALA A 295 ( 0.0A)VAL A 305 ( 0.6A)ILE A 352 ( 0.6A) | 0.77A | 3a2qA-2pnnA:undetectable | 3a2qA-2pnnA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pvz | PRPF METHYLACONITATEISOMERASE (Shewanellaoneidensis) |
PF04303(PrpF) | 4 | GLY A 24ALA A 14VAL A 392ILE A 51 | NoneEDO A1007 (-4.8A)NoneNone | 0.77A | 3a2qA-2pvzA:undetectable | 3a2qA-2pvzA:24.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r8w | AGR_C_1641P (Agrobacteriumfabrum) |
PF00701(DHDPS) | 4 | GLY A 109ALA A 122ALA A 125VAL A 155 | None | 0.80A | 3a2qA-2r8wA:undetectable | 3a2qA-2r8wA:24.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ys6 | PHOSPHORIBOSYLGLYCINAMIDE SYNTHETASE (Geobacilluskaustophilus) |
PF01071(GARS_A)PF02843(GARS_C)PF02844(GARS_N) | 4 | GLY A 33ASN A 34ALA A 16VAL A 40 | None | 0.79A | 3a2qA-2ys6A:undetectable | 3a2qA-2ys6A:24.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c4a | PROBABLE TRYPTOPHANHYDROXYLASE VIOD (Chromobacteriumviolaceum) |
no annotation | 4 | GLY A 9ALA A 285VAL A 136ILE A 30 | FAD A 401 (-3.4A)FAD A 401 ( 4.5A)NoneNone | 0.79A | 3a2qA-3c4aA:undetectable | 3a2qA-3c4aA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cvo | METHYLTRANSFERASE-LIKE PROTEIN OFUNKNOWN FUNCTION (Ruegeriapomeroyi) |
no annotation | 4 | GLY A 39ALA A 45VAL A 53ILE A 83 | None | 0.73A | 3a2qA-3cvoA:undetectable | 3a2qA-3cvoA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e02 | UNCHARACTERIZEDPROTEIN DUF849 (Paraburkholderiaxenovorans) |
PF05853(BKACE) | 4 | GLY A 37ALA A 45ALA A 80VAL A 276 | None | 0.74A | 3a2qA-3e02A:undetectable | 3a2qA-3e02A:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ezx | MONOMETHYLAMINECORRINOID PROTEIN 1 (Methanosarcinabarkeri) |
PF02310(B12-binding)PF02607(B12-binding_2) | 4 | GLY A 162ALA A 154VAL A 188ILE A 196 | None | 0.72A | 3a2qA-3ezxA:undetectable | 3a2qA-3ezxA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f8r | THIOREDOXINREDUCTASE (TRXB-3) (Sulfolobussolfataricus) |
PF07992(Pyr_redox_2) | 4 | GLY A 120ALA A 308ALA A 30ILE A 269 | None | 0.81A | 3a2qA-3f8rA:undetectable | 3a2qA-3f8rA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fj4 | MUCONATECYCLOISOMERASE (Pseudomonasprotegens) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | GLY A 109SER A 112ALA A 313ILE A 69 | None | 0.79A | 3a2qA-3fj4A:undetectable | 3a2qA-3fj4A:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hbj | FLAVONOID3-O-GLUCOSYLTRANSFERASE (Medicagotruncatula) |
PF00201(UDPGT) | 5 | GLY A 246SER A 441ALA A 431ALA A 434VAL A 363 | None | 1.14A | 3a2qA-3hbjA:undetectable | 3a2qA-3hbjA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hxl | UNCHARACTERIZEDPROTEIN DSY3957 (Desulfitobacteriumhafniense) |
PF04984(Phage_sheath_1)PF17481(Phage_sheath_1N)PF17482(Phage_sheath_1C) | 4 | GLY A 181ASN A 91ALA A 112ILE A 41 | None | 0.79A | 3a2qA-3hxlA:undetectable | 3a2qA-3hxlA:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hxt | 5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE (Homo sapiens) |
PF01812(5-FTHF_cyc-lig) | 4 | GLY A 138ALA A 172ALA A 174VAL A 192 | None | 0.72A | 3a2qA-3hxtA:undetectable | 3a2qA-3hxtA:17.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jcu | OXYGEN-EVOLVINGENHANCER PROTEIN 2,CHLOROPLASTIC (Spinaciaoleracea) |
PF01789(PsbP) | 4 | GLY P 89ALA P 111ALA P 109VAL P 131 | None | 0.70A | 3a2qA-3jcuP:undetectable | 3a2qA-3jcuP:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ju8 | SUCCINYLGLUTAMICSEMIALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00171(Aldedh) | 4 | GLY A 155ASN A 154ALA A 160VAL A 167 | None | 0.76A | 3a2qA-3ju8A:undetectable | 3a2qA-3ju8A:25.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kbe | SUPEROXIDE DISMUTASE[CU-ZN] (Caenorhabditiselegans) |
PF00080(Sod_Cu) | 4 | GLY A 121ALA A 146ALA A 144VAL A 13 | None | 0.77A | 3a2qA-3kbeA:undetectable | 3a2qA-3kbeA:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3krt | CROTONYL COAREDUCTASE (Streptomycescoelicolor) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLY A 122ALA A 185ALA A 182VAL A 187 | None | 0.68A | 3a2qA-3krtA:undetectable | 3a2qA-3krtA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l76 | ASPARTOKINASE (Synechocystissp. PCC 6803) |
PF00696(AA_kinase)PF01842(ACT)PF13840(ACT_7) | 4 | ALA A 584ALA A 587VAL A 530ILE A 558 | NoneNoneNoneTHR A 601 (-3.7A) | 0.68A | 3a2qA-3l76A:undetectable | 3a2qA-3l76A:24.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lhi | PUTATIVE6-PHOSPHOGLUCONOLACTONASE (Neisseriagonorrhoeae) |
PF01182(Glucosamine_iso) | 4 | GLY A 133SER A 40ALA A 67VAL A 217 | None | 0.75A | 3a2qA-3lhiA:undetectable | 3a2qA-3lhiA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mah | ASPARTOKINASE (Porphyromonasgingivalis) |
PF13840(ACT_7) | 4 | GLY A 403ALA A 430ALA A 433VAL A 422 | None | 0.79A | 3a2qA-3mahA:undetectable | 3a2qA-3mahA:17.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nlc | UNCHARACTERIZEDPROTEIN VP0956 (Vibrioparahaemolyticus) |
no annotation | 4 | GLY A 106ALA A 517VAL A 260ILE A 125 | FAD A 601 (-3.3A)FAD A 601 (-3.4A)NoneNone | 0.75A | 3a2qA-3nlcA:undetectable | 3a2qA-3nlcA:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nx4 | PUTATIVEOXIDOREDUCTASE (Salmonellaenterica) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLY A 62ALA A 102ALA A 99VAL A 104 | None | 0.78A | 3a2qA-3nx4A:undetectable | 3a2qA-3nx4A:22.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nzq | BIOSYNTHETICARGININEDECARBOXYLASE (Escherichiacoli) |
PF02784(Orn_Arg_deC_N) | 4 | GLY A 362ALA A 367ALA A 567ILE A 103 | SO4 A 701 (-3.5A)NoneNoneNone | 0.75A | 3a2qA-3nzqA:undetectable | 3a2qA-3nzqA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3obe | SUGAR PHOSPHATEISOMERASE/EPIMERASE (Parabacteroidesdistasonis) |
PF01261(AP_endonuc_2) | 4 | GLY A 66ASN A 65ALA A 113ALA A 71 | None | 0.80A | 3a2qA-3obeA:undetectable | 3a2qA-3obeA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3omb | EXTRACELLULARSOLUTE-BINDINGPROTEIN, FAMILY 1 (Bifidobacteriumlongum) |
PF01547(SBP_bac_1) | 4 | ASN A 98ALA A 365ALA A 369ILE A 94 | None | 0.76A | 3a2qA-3ombA:undetectable | 3a2qA-3ombA:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ot1 | 4-METHYL-5(B-HYDROXYETHYL)-THIAZOLEMONOPHOSPHATEBIOSYNTHESIS ENZYME (Vibrio cholerae) |
PF01965(DJ-1_PfpI) | 4 | GLY B 199ALA B 169ALA B 172VAL B 146 | None | 0.74A | 3a2qA-3ot1B:undetectable | 3a2qA-3ot1B:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q6d | PROLINE DIPEPTIDASE (Bacillusanthracis) |
PF00557(Peptidase_M24)PF01321(Creatinase_N) | 5 | GLY A 214SER A 222ALA A 176ALA A 139ILE A 183 | None | 1.24A | 3a2qA-3q6dA:undetectable | 3a2qA-3q6dA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT M (Escherichiacoli) |
no annotation | 4 | GLY M 333ALA M 284ALA M 287VAL M 504 | None | 0.81A | 3a2qA-3rkoM:undetectable | 3a2qA-3rkoM:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ta6 | TRIOSEPHOSPHATEISOMERASE (Mycobacteriumtuberculosis) |
PF00121(TIM) | 4 | GLY A 217ALA A 188ALA A 183VAL A 233 | None | 0.77A | 3a2qA-3ta6A:undetectable | 3a2qA-3ta6A:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tt2 | GCN5-RELATEDN-ACETYLTRANSFERASE (Sphaerobacterthermophilus) |
PF00583(Acetyltransf_1) | 4 | GLY A 98ALA A 72ALA A 70VAL A 84 | SO4 A 338 ( 3.3A)NoneNoneNone | 0.77A | 3a2qA-3tt2A:undetectable | 3a2qA-3tt2A:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ufi | HYPOTHETICAL PROTEINBACOVA_04980 (Bacteroidesovatus) |
PF13149(Mfa_like_1) | 4 | ALA A 165ALA A 163VAL A 168ILE A 111 | None | 0.76A | 3a2qA-3ufiA:undetectable | 3a2qA-3ufiA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vkw | REPLICASE LARGESUBUNIT (Tobacco mosaicvirus) |
PF01443(Viral_helicase1) | 4 | ASN A 917SER A 824ALA A 928ALA A 826 | None | 0.74A | 3a2qA-3vkwA:undetectable | 3a2qA-3vkwA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vov | GLUCOKINASE (Thermusthermophilus) |
PF00480(ROK) | 4 | GLY A 135ALA A 181ALA A 185VAL A 225 | None | 0.80A | 3a2qA-3vovA:undetectable | 3a2qA-3vovA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vv3 | DESEASIN MCP-01 (Pseudoalteromonassp. SM9913) |
PF00082(Peptidase_S8) | 4 | ASN A 321SER A 301ALA A 327VAL A 285 | None | 0.65A | 3a2qA-3vv3A:undetectable | 3a2qA-3vv3A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zyy | IRON-SULFUR CLUSTERBINDING PROTEIN (Carboxydothermushydrogenoformans) |
PF00111(Fer2)PF14574(DUF4445) | 4 | GLY X 360SER X 573ALA X 541ILE X 594 | None | 0.80A | 3a2qA-3zyyX:undetectable | 3a2qA-3zyyX:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ab5 | TRANSCRIPTIONALREGULATOR, LYSRFAMILY (Neisseriameningitidis) |
PF03466(LysR_substrate) | 4 | GLY A 138ALA A 148ALA A 145VAL A 150 | None | 0.62A | 3a2qA-4ab5A:undetectable | 3a2qA-4ab5A:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b9y | ALPHA-GLUCOSIDASE,PUTATIVE, ADG31B (Cellvibriojaponicus) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF16338(DUF4968)PF17137(DUF5110) | 4 | GLY A 390ALA A 356ALA A 359VAL A 346 | None | 0.77A | 3a2qA-4b9yA:undetectable | 3a2qA-4b9yA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cn8 | PROXIMAL THREADMATRIX PROTEIN 1 (Mytilusgalloprovincialis) |
PF00092(VWA) | 4 | GLY A 338ALA A 344VAL A 364ILE A 409 | None | 0.75A | 3a2qA-4cn8A:undetectable | 3a2qA-4cn8A:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dna | PROBABLE GLUTATHIONEREDUCTASE (Sinorhizobiummeliloti) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | GLY A 14ALA A 317VAL A 138ILE A 33 | FAD A 500 (-3.2A)FAD A 500 ( 3.8A)NoneNone | 0.76A | 3a2qA-4dnaA:undetectable | 3a2qA-4dnaA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4emy | AMINOTRANSFERASECLASS I AND II (Anaerococcusprevotii) |
PF00155(Aminotran_1_2) | 4 | ALA A 269ALA A 110VAL A 85ILE A 99 | None | 0.79A | 3a2qA-4emyA:undetectable | 3a2qA-4emyA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f9o | HEXOKINASE-1 (Homo sapiens) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 4 | GLY A 135ALA A 201VAL A 150ILE A 92 | None | 0.65A | 3a2qA-4f9oA:undetectable | 3a2qA-4f9oA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hb9 | SIMILARITIES WITHPROBABLEMONOOXYGENASE (Photorhabduslaumondii) |
PF01494(FAD_binding_3) | 4 | GLY A 9ALA A 333VAL A 158ILE A 28 | FAD A 501 (-3.2A)FAD A 501 (-3.5A)NoneNone | 0.79A | 3a2qA-4hb9A:undetectable | 3a2qA-4hb9A:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i3u | ALDEHYDEDEHYDROGENASE (NAD+) (Sinorhizobiummeliloti) |
PF00171(Aldedh) | 5 | GLY A 218ALA A 50ALA A 47VAL A 179ILE A 154 | None | 1.17A | 3a2qA-4i3uA:undetectable | 3a2qA-4i3uA:23.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ibo | GLUCONATEDEHYDROGENASE (Agrobacteriumfabrum) |
PF13561(adh_short_C2) | 4 | GLY A 30ALA A 230VAL A 93ILE A 38 | None | 0.81A | 3a2qA-4iboA:undetectable | 3a2qA-4iboA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4isb | LONG CHAIN FATTYACID COA LIGASEFADD10 (Mycobacteriumtuberculosis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | GLY A 468ALA A 526ALA A 529ILE A 428 | None | 0.78A | 3a2qA-4isbA:undetectable | 3a2qA-4isbA:23.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jbh | ALCOHOLDEHYDROGENASE (ZINC) (Pyrobaculumaerophilum) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLY A 60ALA A 125ALA A 122VAL A 127 | None | 0.73A | 3a2qA-4jbhA:undetectable | 3a2qA-4jbhA:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jlv | C-TERMINAL FRAGMENTOF MEMBRANE PROTEINCAPA1, PUTATIVEUNCHARACTERIZEDPROTEIN CAPB1 (Staphylococcusaureus) |
PF13614(AAA_31) | 4 | GLY A1136ALA A1173VAL A1144ILE A1101 | None | 0.70A | 3a2qA-4jlvA:undetectable | 3a2qA-4jlvA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kna | N-SUCCINYLGLUTAMATE5-SEMIALDEHYDEDEHYDROGENASE (Burkholderiathailandensis) |
PF00171(Aldedh) | 4 | GLY A 154ASN A 153ALA A 159VAL A 166 | None | 0.74A | 3a2qA-4knaA:undetectable | 3a2qA-4knaA:24.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q9d | BENZOYLFORMATEDECARBOXYLASE (Mycolicibacteriumsmegmatis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | GLY A 406ALA A 411ALA A 55VAL A 375 | None | 0.75A | 3a2qA-4q9dA:undetectable | 3a2qA-4q9dA:24.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qnx | TRNA(MO5U34)-METHYLTRANSFERASE (Escherichiacoli) |
PF08003(Methyltransf_9) | 4 | GLY A 231ALA A 255ALA A 257VAL A 275 | None | 0.74A | 3a2qA-4qnxA:undetectable | 3a2qA-4qnxA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ueg | GLYCOGENIN-2 (Homo sapiens) |
PF01501(Glyco_transf_8) | 4 | ALA A 12ALA A 105VAL A 45ILE A 52 | None | 0.59A | 3a2qA-4uegA:undetectable | 3a2qA-4uegA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uwm | 3,6-DIKETOCAMPHANE1,6 MONOOXYGENASE (Pseudomonasputida) |
PF00296(Bac_luciferase) | 4 | GLY A 26SER A 29ALA A 348ILE A 54 | None | 0.76A | 3a2qA-4uwmA:undetectable | 3a2qA-4uwmA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wen | K88 FIMBRIAL PROTEINAC (Escherichiacoli) |
PF02432(Fimbrial_K88) | 4 | GLY A 279ALA A 253VAL A 125ILE A 52 | None | 0.77A | 3a2qA-4wenA:undetectable | 3a2qA-4wenA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wp0 | KYNURENINE--OXOGLUTARATE TRANSAMINASE 1 (Homo sapiens) |
PF00155(Aminotran_1_2) | 4 | GLY A 188ASN A 184SER A 157VAL A 381 | None | 0.78A | 3a2qA-4wp0A:undetectable | 3a2qA-4wp0A:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xgk | UDP-GALACTOPYRANOSEMUTASE (Corynebacteriumdiphtheriae) |
PF03275(GLF)PF13450(NAD_binding_8) | 4 | GLY A 12ALA A 370VAL A 238ILE A 32 | FDA A 403 (-3.3A)FDA A 403 (-3.5A)NoneNone | 0.74A | 3a2qA-4xgkA:undetectable | 3a2qA-4xgkA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y1b | ANTE (Streptomycessp. NRRL 2288) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLY A 94ALA A 158ALA A 155VAL A 160 | None | 0.81A | 3a2qA-4y1bA:undetectable | 3a2qA-4y1bA:22.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4yji | ARYL ACYLAMIDASE (bacteriumCSBL00001) |
PF01425(Amidase) | 4 | GLY A 129ALA A 56VAL A 31ILE A 38 | None | 0.74A | 3a2qA-4yjiA:47.9 | 3a2qA-4yjiA:31.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b37 | TRYPTOPHANDEHYDROGENASE (Nostocpunctiforme) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 4 | GLY A 176ALA A 205VAL A 216ILE A 222 | None | 0.79A | 3a2qA-5b37A:undetectable | 3a2qA-5b37A:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b8i | CALCINEURIN SUBUNITB, VARIANTSERINE/THREONINE-PROTEIN PHOSPHATASE (Coccidioidesimmitis) |
PF00149(Metallophos)PF13202(EF-hand_5)PF13499(EF-hand_7) | 4 | GLY B 110ASN B 109VAL A 367ILE B 137 | None | 0.79A | 3a2qA-5b8iB:undetectable | 3a2qA-5b8iB:17.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cju | ISOBUTYRYL-COAMUTASE FUSED (Cupriavidusmetallidurans) |
PF01642(MM_CoA_mutase)PF02310(B12-binding)PF03308(ArgK) | 4 | GLY A 190ASN A 189ALA A 291VAL A 295 | None | 0.74A | 3a2qA-5cjuA:undetectable | 3a2qA-5cjuA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fcu | JR4 FAB LIGHT CHAIN (Macaca mulatta) |
PF07654(C1-set)PF07686(V-set) | 4 | GLY L 25ALA L 71VAL L 33ILE L 97 | None | 0.78A | 3a2qA-5fcuL:undetectable | 3a2qA-5fcuL:17.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j60 | THIOREDOXINREDUCTASE (Gloeobacterviolaceus) |
PF07992(Pyr_redox_2) | 4 | GLY A 14ALA A 290VAL A 109ILE A 33 | FAD A 401 (-3.3A)FAD A 401 (-3.4A)NoneNone | 0.65A | 3a2qA-5j60A:undetectable | 3a2qA-5j60A:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k6o | B-GLUCOSIDASE (metagenome) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | GLY A 508SER A 541ALA A 543VAL A 579 | None | 0.81A | 3a2qA-5k6oA:undetectable | 3a2qA-5k6oA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5li8 | PUTATIVE CYTOCHROMEP450 126 (Mycobacteriumtuberculosis) |
PF00067(p450) | 4 | GLY A 265ALA A 270VAL A 389ILE A 404 | None | 0.81A | 3a2qA-5li8A:undetectable | 3a2qA-5li8A:24.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mr6 | XIAF PROTEIN (Streptomycessp.) |
PF08028(Acyl-CoA_dh_2) | 4 | GLY A 250SER A 79ALA A 365ILE A 293 | None | 0.78A | 3a2qA-5mr6A:undetectable | 3a2qA-5mr6A:23.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mzs | FERRIC ENTEROBACTINRECEPTOR (Pseudomonasaeruginosa) |
no annotation | 4 | GLY A 129ALA A 462ALA A 460ILE A 76 | None | 0.80A | 3a2qA-5mzsA:undetectable | 3a2qA-5mzsA:10.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ngj | TAIL TUBE PROTEIN (Escherichiavirus T5) |
no annotation | 4 | SER A 273ALA A 267VAL A 334ILE A 213 | None | 0.69A | 3a2qA-5ngjA:undetectable | 3a2qA-5ngjA:9.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nh1 | GASDERMIN-D (Homo sapiens) |
PF04598(Gasdermin) | 4 | GLY A 350ALA A 332ALA A 328VAL A 342 | None | 0.70A | 3a2qA-5nh1A:undetectable | 3a2qA-5nh1A:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u0l | N-SUCCINYLGLUTAMATE5-SEMIALDEHYDEDEHYDROGENASE (Marinobacterhydrocarbonoclasticus) |
PF00171(Aldedh) | 4 | GLY A 158ASN A 157ALA A 163VAL A 170 | 8YP A 507 (-2.9A)NoneNoneNone | 0.74A | 3a2qA-5u0lA:undetectable | 3a2qA-5u0lA:24.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u39 | UDP-3-O-ACYL-N-ACETYLGLUCOSAMINEDEACETYLASE (Pseudomonasaeruginosa) |
PF03331(LpxC) | 4 | GLY A 227ASN A 224VAL A 164ILE A 215 | None | 0.65A | 3a2qA-5u39A:undetectable | 3a2qA-5u39A:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u9p | GLUCONATE5-DEHYDROGENASE (Burkholderiacenocepacia) |
PF13561(adh_short_C2) | 4 | GLY A 31ALA A 231VAL A 94ILE A 39 | None | 0.74A | 3a2qA-5u9pA:undetectable | 3a2qA-5u9pA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vwn | TRIOSEPHOSPHATEISOMERASE (Trichomonasvaginalis) |
no annotation | 4 | GLY A 205ALA A 176ALA A 171VAL A 221 | NoneNoneNone NA A 301 (-4.6A) | 0.78A | 3a2qA-5vwnA:undetectable | 3a2qA-5vwnA:10.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xt3 | PHOSPHODIESTERASEACTING ON CYCLICDINUCLEOTIDES (Staphylococcusaureus) |
no annotation | 4 | GLY A 356ALA A 361VAL A 338ILE A 370 | None | 0.66A | 3a2qA-5xt3A:undetectable | 3a2qA-5xt3A:9.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | 40S RIBOSOMALPROTEIN S16,PUTATIVE (Trichomonasvaginalis) |
PF00380(Ribosomal_S9) | 4 | ALA Q 15ALA Q 13VAL Q 64ILE Q 45 | None | 0.79A | 3a2qA-5xyiQ:undetectable | 3a2qA-5xyiQ:13.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6amw | TYROSINE-PROTEINKINASE ABL1 (Homo sapiens) |
PF00017(SH2)PF00018(SH3_1) | 4 | GLY A 126ASN A 125ALA A 121VAL A 130 | None | 0.74A | 3a2qA-6amwA:undetectable | 3a2qA-6amwA:17.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b0k | IOTA-CARRAGEENANSULFATASE (Pseudoalteromonas) |
no annotation | 4 | GLY A 88ALA A 74ALA A 341ILE A 94 | None | 0.76A | 3a2qA-6b0kA:undetectable | 3a2qA-6b0kA:11.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bja | ACETYL-COAACETYLTRANSFERASE A (Ascaris suum) |
no annotation | 4 | GLY A 58ASN A 59ALA A 257ILE A 69 | None | 0.74A | 3a2qA-6bjaA:undetectable | 3a2qA-6bjaA:10.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cr0 | (S)-6-HYDROXYNICOTINE OXIDASE (Shinella sp.HZN7) |
no annotation | 4 | GLY A 14ALA A 418VAL A 257ILE A 33 | FAD A 507 ( 3.7A)FAD A 507 (-3.4A)NoneNone | 0.79A | 3a2qA-6cr0A:undetectable | 3a2qA-6cr0A:11.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6et9 | ACETYL-COAACETYLTRANSFERASETHIOLASE (Methanothermococcusthermolithotrophicus) |
no annotation | 4 | GLY A 50ASN A 51ALA A 213ILE A 63 | None | 0.78A | 3a2qA-6et9A:undetectable | 3a2qA-6et9A:11.25 |