SIMILAR PATTERNS OF AMINO ACIDS FOR 2ZW9_B_SAMB801_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cnv | CONCANAVALIN B (Canavaliaensiformis) |
PF00704(Glyco_hydro_18) | 4 | ILE A 279ASN A 27ASP A 270TYR A 275 | None | 1.12A | 2zw9B-1cnvA:undetectable | 2zw9B-1cnvA:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1exf | EXFOLIATVE TOXIN A (Staphylococcusaureus) |
PF13365(Trypsin_2) | 4 | ASN A 194SER A 197ASP A 144SER A 41 | None | 1.03A | 2zw9B-1exfA:undetectable | 2zw9B-1exfA:17.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hzo | BETA-LACTAMASE (Proteusvulgaris) |
PF13354(Beta-lactamase2) | 4 | ILE A 247SER A 130TYR A 264SER A 72 | NoneMES A1000 (-2.7A)NoneNone | 1.00A | 2zw9B-1hzoA:undetectable | 2zw9B-1hzoA:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r5m | SIR4-INTERACTINGPROTEIN SIF2 (Saccharomycescerevisiae) |
PF00400(WD40)PF12894(ANAPC4_WD40) | 4 | ILE A 445SER A 363ASP A 421SER A 417 | None | 1.16A | 2zw9B-1r5mA:6.5 | 2zw9B-1r5mA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ua7 | ALPHA-AMYLASE (Bacillussubtilis) |
PF00128(Alpha-amylase) | 4 | ILE A 235SER A 278ARG A 306TYR A 231 | None | 1.15A | 2zw9B-1ua7A:undetectable | 2zw9B-1ua7A:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uls | PUTATIVE3-OXOACYL-ACYLCARRIER PROTEINREDUCTASE (Thermusthermophilus) |
PF13561(adh_short_C2) | 4 | ASN A 108SER A 151TYR A 84SER A 136 | None | 1.09A | 2zw9B-1ulsA:5.4 | 2zw9B-1ulsA:16.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uzn | 3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE (Mycobacteriumtuberculosis) |
PF13561(adh_short_C2) | 4 | ILE A 138ASN A 112SER A 156SER A 140 | None | 1.14A | 2zw9B-1uznA:5.3 | 2zw9B-1uznA:16.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ytm | PHOSPHOENOLPYRUVATECARBOXYKINASE [ATP] (Anaerobiospirillumsucciniciproducens) |
PF01293(PEPCK_ATP) | 4 | ILE A 452ASN A 434SER A 355SER A 366 | None | 1.04A | 2zw9B-1ytmA:undetectable | 2zw9B-1ytmA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z3v | CELLULASE (Phanerochaetechrysosporium) |
PF00840(Glyco_hydro_7) | 4 | ILE A 363ASN A 214LYS A 265SER A 411 | None | 0.89A | 2zw9B-1z3vA:undetectable | 2zw9B-1z3vA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zbh | 3'-5' EXONUCLEASEERI1 (Homo sapiens) |
PF00929(RNase_T)PF02037(SAP) | 4 | ILE A 318ASN A 259SER A 232SER A 329 | NoneNoneNone C F 20 ( 3.3A) | 1.09A | 2zw9B-1zbhA:undetectable | 2zw9B-1zbhA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bi7 | UDP-GALACTOPYRANOSEMUTASE (Klebsiellapneumoniae) |
PF03275(GLF)PF13450(NAD_binding_8) | 4 | ILE A 205SER A 42TYR A 72SER A 14 | NoneFAD A1385 ( 3.8A)NoneFAD A1385 (-2.6A) | 0.97A | 2zw9B-2bi7A:undetectable | 2zw9B-2bi7A:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bpa | PROTEIN (SUBUNIT OFBACTERIOPHAGEPHIX174) (Escherichiavirus phiX174) |
PF02305(Phage_F) | 4 | ILE 1 219ASP 1 231TYR 1 215SER 1 227 | None | 1.09A | 2zw9B-2bpa1:undetectable | 2zw9B-2bpa1:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c07 | 3-OXOACYL-(ACYL-CARRIER PROTEIN)REDUCTASE (Plasmodiumfalciparum) |
PF13561(adh_short_C2) | 4 | ILE A 197ASN A 171SER A 215SER A 199 | None | 1.09A | 2zw9B-2c07A:5.8 | 2zw9B-2c07A:18.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hrb | CARBONYL REDUCTASE[NADPH] 3 (Homo sapiens) |
PF00106(adh_short) | 4 | ILE A 138ASN A 114SER A 197SER A 140 | NAP A1001 (-4.2A)NoneNoneNAP A1001 ( 4.0A) | 1.14A | 2zw9B-2hrbA:5.8 | 2zw9B-2hrbA:16.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hsd | 3-ALPHA, 20BETA-HYDROXYSTEROIDDEHYDROGENASE (Streptomycesexfoliatus) |
PF13561(adh_short_C2) | 4 | ILE A 137ASN A 111SER A 155SER A 139 | NAD A 256 (-4.6A)NoneNoneNAD A 256 (-3.4A) | 1.11A | 2zw9B-2hsdA:5.8 | 2zw9B-2hsdA:15.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i71 | HYPOTHETICAL PROTEIN (Sulfolobussolfataricus) |
PF09455(Cas_DxTHG) | 4 | ILE A 22SER A 29ASP A 125TYR A 161 | None | 1.13A | 2zw9B-2i71A:1.8 | 2zw9B-2i71A:20.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k75 | UNCHARACTERIZEDPROTEIN TA0387 (Thermoplasmaacidophilum) |
no annotation | 4 | ILE A 68ASN A 70SER A 87SER A 83 | None | 0.87A | 2zw9B-2k75A:undetectable | 2zw9B-2k75A:9.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2okx | RHAMNOSIDASE B (Bacillus sp.GL1) |
PF05592(Bac_rhamnosid)PF08531(Bac_rhamnosid_N)PF17389(Bac_rhamnosid6H)PF17390(Bac_rhamnosid_C) | 4 | ILE A 195SER A 529ARG A 502ASP A 74 | None | 1.10A | 2zw9B-2okxA:undetectable | 2zw9B-2okxA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ph3 | 3-OXOACYL-[ACYLCARRIER PROTEIN]REDUCTASE (Thermusthermophilus) |
PF13561(adh_short_C2) | 4 | ILE A 137ASN A 111SER A 155SER A 139 | None | 1.06A | 2zw9B-2ph3A:5.1 | 2zw9B-2ph3A:16.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsa | MOSQUITOCIDAL TOXIN (Lysinibacillussphaericus) |
PF05588(Botulinum_HA-17)PF14200(RicinB_lectin_2) | 4 | ILE A 64ASN A 860SER A 735SER A 66 | None | 1.08A | 2zw9B-2vsaA:undetectable | 2zw9B-2vsaA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wyx | BETA-LACTAMSE TOHO-1 (Escherichiacoli) |
PF13354(Beta-lactamase2) | 4 | ILE A 247SER A 130TYR A 264SER A 72 | None | 0.96A | 2zw9B-2wyxA:undetectable | 2zw9B-2wyxA:15.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzf | GLUCOSYLTRANSFERASE (Legionellapneumophila) |
PF16849(Glyco_transf_88) | 4 | ILE A 297ASN A 293ARG A 502ASP A 246 | NoneBGC A1526 (-3.0A)NoneBGC A1526 (-2.7A) | 1.08A | 2zw9B-2wzfA:undetectable | 2zw9B-2wzfA:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ya1 | PUTATIVE ALKALINEAMYLOPULLULANASE (Streptococcuspneumoniae) |
PF00128(Alpha-amylase)PF02922(CBM_48)PF03714(PUD) | 4 | ILE A 335ASN A 347SER A 237ASP A 353 | NoneNoneNone NA A2157 (-3.9A) | 1.12A | 2zw9B-2ya1A:undetectable | 2zw9B-2ya1A:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zoa | PHOSPHOHYDROLASE (Klebsiellaaerogenes) |
PF00149(Metallophos) | 4 | ILE A 51SER A 121ASP A 8SER A 48 | NoneNoneFE2 A 275 ( 3.1A)None | 1.01A | 2zw9B-2zoaA:2.1 | 2zw9B-2zoaA:16.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2zwa | LEUCINE CARBOXYLMETHYLTRANSFERASE 2 (Saccharomycescerevisiae) |
PF04072(LCM)PF13418(Kelch_4) | 8 | ILE A 27ASN A 31SER A 34LYS A 38ARG A 88ASP A 146TYR A 147SER A 226 | SAH A 801 (-4.4A)SAH A 801 (-4.6A)SAH A 801 (-3.6A)SAH A 801 (-2.8A)SAH A 801 (-3.9A)SAH A 801 (-2.9A)SAH A 801 (-3.8A)SAH A 801 (-4.6A) | 0.31A | 2zw9B-2zwaA:56.8 | 2zw9B-2zwaA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a9g | PUTATIVEUNCHARACTERIZEDPROTEIN (Pyrobaculumaerophilum) |
PF07995(GSDH) | 4 | ILE A 342SER A 39ASP A 339SER A 367 | None | 1.05A | 2zw9B-3a9gA:1.7 | 2zw9B-3a9gA:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bfg | CLASS ABETA-LACTAMASE SED1 (Citrobactersedlakii) |
PF13354(Beta-lactamase2) | 4 | ILE A 247SER A 130TYR A 264SER A 72 | NoneMER A 301 (-2.6A)NoneNone | 0.95A | 2zw9B-3bfgA:undetectable | 2zw9B-3bfgA:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bsf | AT4G34840 (Arabidopsisthaliana) |
PF01048(PNP_UDP_1) | 4 | ILE A 93ASN A 60SER A 14ARG A 11 | None | 1.16A | 2zw9B-3bsfA:undetectable | 2zw9B-3bsfA:17.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eeg | 2-ISOPROPYLMALATESYNTHASE (Cytophagahutchinsonii) |
PF00682(HMGL-like) | 4 | ILE A 83SER A 57LYS A 28SER A 50 | None | 1.05A | 2zw9B-3eegA:undetectable | 2zw9B-3eegA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3emk | GLUCOSE/RIBITOLDEHYDROGENASE (Brucellamelitensis) |
PF13561(adh_short_C2) | 4 | ILE A 137ASN A 111SER A 155SER A 139 | None | 1.06A | 2zw9B-3emkA:5.7 | 2zw9B-3emkA:14.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fed | GLUTAMATECARBOXYPEPTIDASE III (Homo sapiens) |
PF02225(PA)PF04253(TFR_dimer)PF04389(Peptidase_M28) | 4 | ILE A 440SER A 436ARG A 663SER A 522 | None | 1.09A | 2zw9B-3fedA:undetectable | 2zw9B-3fedA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fzy | RTX TOXIN RTXA (Vibrio cholerae) |
PF11713(Peptidase_C80) | 4 | ILE A3584LYS A3511ARG A3457SER A3632 | UNX A 327 (-4.3A) CL A 1 ( 4.2A)IHP A8000 ( 4.0A)None | 1.05A | 2zw9B-3fzyA:undetectable | 2zw9B-3fzyA:15.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gcd | RTX TOXIN RTXA (Vibrio cholerae) |
PF11713(Peptidase_C80) | 4 | ILE A 156LYS A 83ARG A 29SER A 204 | NoneNoneIHP A 214 (-4.0A)None | 0.99A | 2zw9B-3gcdA:undetectable | 2zw9B-3gcdA:13.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h09 | IMMUNOGLOBULIN A1PROTEASE (Haemophilusinfluenzae) |
PF02395(Peptidase_S6)PF03212(Pertactin) | 4 | ILE A 86SER A 137TYR A 239SER A 102 | None | 1.03A | 2zw9B-3h09A:undetectable | 2zw9B-3h09A:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h4r | EXODEOXYRIBONUCLEASE8 (Escherichiacoli) |
PF12684(DUF3799) | 4 | ILE A 614ASN A 835TYR A 629SER A 617 | None | 1.10A | 2zw9B-3h4rA:undetectable | 2zw9B-3h4rA:16.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hzs | MONOFUNCTIONALGLYCOSYLTRANSFERASE (Staphylococcusaureus) |
PF00912(Transgly) | 4 | ILE A 97SER A 221ARG A 241TYR A 254 | None | 1.05A | 2zw9B-3hzsA:undetectable | 2zw9B-3hzsA:15.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3igo | CALMODULIN-DOMAINPROTEIN KINASE 1 (Cryptosporidiumparvum) |
PF00069(Pkinase)PF13499(EF-hand_7) | 4 | ILE A 456ASP A 131TYR A 452SER A 374 | None | 1.01A | 2zw9B-3igoA:undetectable | 2zw9B-3igoA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iuu | PUTATIVEMETALLOPEPTIDASE (Chelativoranssp. BNC1) |
PF07171(MlrC_C)PF07364(DUF1485) | 4 | ILE A 154ASP A 226TYR A 248SER A 156 | None | 1.15A | 2zw9B-3iuuA:undetectable | 2zw9B-3iuuA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jr3 | NAD-DEPENDENTDEACETYLASE (Thermotogamaritima) |
PF02146(SIR2) | 4 | ILE A 50ASN A 46SER A 44SER A 55 | None | 1.09A | 2zw9B-3jr3A:2.4 | 2zw9B-3jr3A:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3khd | PYRUVATE KINASE (Plasmodiumfalciparum) |
PF00224(PK)PF02887(PK_C) | 4 | ILE A 396ASN A 312TYR A 438SER A 391 | None | 1.10A | 2zw9B-3khdA:undetectable | 2zw9B-3khdA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lhl | PUTATIVE AGMATINASE (Clostridioidesdifficile) |
PF00491(Arginase) | 4 | ILE A 97ASN A 22TYR A 18SER A 101 | None | 1.06A | 2zw9B-3lhlA:3.4 | 2zw9B-3lhlA:18.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lq0 | PROASTACIN (Astacus astacus) |
PF01400(Astacin) | 4 | ILE A 4LYS A 179TYR A 13SER A 153 | None | 1.10A | 2zw9B-3lq0A:undetectable | 2zw9B-3lq0A:16.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m0e | TRANSCRIPTIONALREGULATOR (NTRCFAMILY) (Aquifexaeolicus) |
PF00158(Sigma54_activat) | 4 | ILE A 165ASN A 280SER A 169ARG A 357 | NoneATP A 400 (-4.2A)ATP A 400 (-2.6A)ATP A 400 (-3.3A) | 1.02A | 2zw9B-3m0eA:2.5 | 2zw9B-3m0eA:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n2e | SHIKIMATE KINASE (Helicobacterpylori) |
PF01202(SKI) | 4 | ILE A 82SER A 12ASP A 33SER A 77 | None | 0.99A | 2zw9B-3n2eA:undetectable | 2zw9B-3n2eA:11.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ne8 | N-ACETYLMURAMOYL-L-ALANINE AMIDASE (Bartonellahenselae) |
PF01520(Amidase_3) | 4 | ASN A 329SER A 332LYS A 336TYR A 401 | GOL A 413 ( 4.0A)NoneNoneGOL A 413 ( 4.9A) | 1.02A | 2zw9B-3ne8A:undetectable | 2zw9B-3ne8A:15.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oja | ANOPHELESPLASMODIUM-RESPONSIVE LEUCINE-RICHREPEAT PROTEIN 1 (Anophelesgambiae) |
PF13855(LRR_8) | 4 | ASN B 391ARG B 621ASP B 387SER B 413 | None | 1.11A | 2zw9B-3ojaB:undetectable | 2zw9B-3ojaB:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p4g | ANTIFREEZE PROTEIN (Marinomonasprimoryensis) |
no annotation | 4 | ILE A 164ASN A 129SER A 131SER A 169 | None MG A 325 ( 4.8A)NoneNone | 1.11A | 2zw9B-3p4gA:undetectable | 2zw9B-3p4gA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q4d | MANDELATERACEMASE/MUCONATELACTONIZING ENZYMEFAMILY POSSIBLECHLOROMUCONATECYCLOISOMERASE (Cytophagahutchinsonii) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ILE A 98ASN A 103SER A 85SER A 96 | None | 1.11A | 2zw9B-3q4dA:undetectable | 2zw9B-3q4dA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qjg | EPIDERMINBIOSYNTHESIS PROTEINEPID (Staphylococcusaureus) |
PF02441(Flavoprotein) | 4 | ILE A 112ASN A 115SER A 12SER A 84 | NoneFMN A 501 (-4.2A)FMN A 501 (-2.6A)None | 0.94A | 2zw9B-3qjgA:2.9 | 2zw9B-3qjgA:13.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qm2 | PHOSPHOSERINEAMINOTRANSFERASE (Salmonellaenterica) |
PF00266(Aminotran_5) | 4 | ILE A 159ASN A 151SER A 177LYS A 198 | None | 1.09A | 2zw9B-3qm2A:undetectable | 2zw9B-3qm2A:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qp6 | CVIR TRANSCRIPTIONALREGULATOR (Chromobacteriumviolaceum) |
PF00196(GerE)PF03472(Autoind_bind) | 4 | ILE A 69ASN A 67ARG A 10SER A 152 | None | 1.04A | 2zw9B-3qp6A:undetectable | 2zw9B-3qp6A:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sju | KETO REDUCTASE (Streptomycesgriseoruber) |
PF00106(adh_short) | 4 | ILE A 140ASN A 112SER A 158SER A 142 | NDP A 301 (-4.3A)NoneNoneNDP A 301 (-3.7A) | 1.09A | 2zw9B-3sjuA:undetectable | 2zw9B-3sjuA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3thz | DNA MISMATCH REPAIRPROTEIN MSH2 (Homo sapiens) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05190(MutS_IV)PF05192(MutS_III) | 4 | SER A 284ARG A 171TYR A 121SER A 129 | None | 1.10A | 2zw9B-3thzA:undetectable | 2zw9B-3thzA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tsc | PUTATIVEOXIDOREDUCTASE (Mycobacteriumavium) |
PF13561(adh_short_C2) | 4 | ILE A 155ASN A 128SER A 173SER A 157 | NAD A 274 (-4.6A)NoneNoneNAD A 274 (-3.6A) | 1.06A | 2zw9B-3tscA:2.5 | 2zw9B-3tscA:17.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uf0 | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Beutenbergiacavernae) |
PF13561(adh_short_C2) | 4 | ILE A 141ASN A 115SER A 159SER A 143 | NAP A 274 (-4.3A)NoneNoneNAP A 274 (-3.5A) | 1.15A | 2zw9B-3uf0A:5.4 | 2zw9B-3uf0A:15.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wqo | UNCHARACTERIZEDPROTEIN MJ1311 (Methanocaldococcusjannaschii) |
PF01261(AP_endonuc_2) | 4 | ILE A 148ASN A 186SER A 184TYR A 152 | None | 1.03A | 2zw9B-3wqoA:undetectable | 2zw9B-3wqoA:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wxb | UNCHARACTERIZEDPROTEIN (Gallus gallus) |
PF00106(adh_short) | 4 | ILE A 157ASN A 120SER A 181SER A 159 | NDP A 300 (-4.4A)NoneNoneEDO A 301 ( 2.5A) | 1.14A | 2zw9B-3wxbA:6.5 | 2zw9B-3wxbA:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zny | CTX-M-12A ENZYME (Klebsiellapneumoniae) |
PF13354(Beta-lactamase2) | 4 | ILE A 247SER A 130TYR A 264SER A 72 | None | 0.92A | 2zw9B-3znyA:undetectable | 2zw9B-3znyA:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b97 | CELLULOSE BINDINGDOMAIN-CONTAININGPROTEIN (Ruminiclostridiumthermocellum) |
PF00942(CBM_3) | 4 | ILE A 47ASN A 117ASP A 121TYR A 45 | NoneNone CA A1152 (-2.9A)None | 0.97A | 2zw9B-4b97A:undetectable | 2zw9B-4b97A:11.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cql | ESTRADIOL17-BETA-DEHYDROGENASE 8 (Homo sapiens) |
PF13561(adh_short_C2) | 4 | ILE A 154ASN A 127SER A 172SER A 156 | NAD A 301 (-4.6A)NoneNoneNAD A 301 (-3.1A) | 1.00A | 2zw9B-4cqlA:5.4 | 2zw9B-4cqlA:17.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cyv | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | ILE B 152ASN B 154TYR B 157SER B 147 | NoneNAG B 211 (-1.9A)NoneNone | 1.11A | 2zw9B-4cyvB:undetectable | 2zw9B-4cyvB:13.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fda | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE (Saccharomycescerevisiae) |
PF00106(adh_short) | 4 | ILE A 181ASN A 144SER A 201SER A 183 | NoneNoneNoneNAP A 301 (-3.3A) | 1.14A | 2zw9B-4fdaA:undetectable | 2zw9B-4fdaA:18.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hhr | ALPHA-DIOXYGENASE (Arabidopsisthaliana) |
PF03098(An_peroxidase) | 4 | ILE A 320ASN A 339ARG A 566TYR A 341 | NoneNone CL A 711 (-3.3A)None | 1.05A | 2zw9B-4hhrA:undetectable | 2zw9B-4hhrA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i5j | SERINE/THREONINE-PROTEIN PHOSPHATASE 2AREGULATORY SUBUNITB'' SUBUNIT ALPHA (Homo sapiens) |
PF13499(EF-hand_7) | 4 | ILE A 249ASN A 237SER A 239SER A 191 | None | 1.13A | 2zw9B-4i5jA:undetectable | 2zw9B-4i5jA:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iop | C-TYPE LECTIN DOMAINFAMILY 2 MEMBER AKILLER CELLLECTIN-LIKE RECEPTORSUBFAMILY F MEMBER 2 (Homo sapiens;Homo sapiens) |
PF00059(Lectin_C)PF00059(Lectin_C) | 4 | ILE A 140ASN A 143SER B 187SER A 145 | None | 1.10A | 2zw9B-4iopA:undetectable | 2zw9B-4iopA:11.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iuy | SHORT CHAINDEHYDROGENASE/REDUCTASE (Acinetobacterbaumannii) |
PF00106(adh_short) | 4 | ILE A 144ASN A 117SER A 162SER A 146 | None | 0.99A | 2zw9B-4iuyA:6.6 | 2zw9B-4iuyA:17.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j0m | SERINE/THREONINE-PROTEIN KINASEBRI1-LIKE 1 (Arabidopsisthaliana) |
PF08263(LRRNT_2)PF13516(LRR_6)PF13855(LRR_8) | 4 | ILE A 363ASN A 344SER A 370SER A 366 | None | 1.10A | 2zw9B-4j0mA:undetectable | 2zw9B-4j0mA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j1y | COMPLEMENT C1SSUBCOMPONENT (Homo sapiens) |
PF00084(Sushi)PF00089(Trypsin) | 4 | ILE A 617SER A 627ARG A 572SER A 654 | None | 1.14A | 2zw9B-4j1yA:undetectable | 2zw9B-4j1yA:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kvl | FATTY ACIDALPHA-OXIDASE (Oryza sativa) |
PF03098(An_peroxidase) | 4 | ILE A 313ASN A 332ARG A 559TYR A 334 | NonePLM A 702 ( 3.6A)PLM A 702 (-2.9A)None | 1.02A | 2zw9B-4kvlA:undetectable | 2zw9B-4kvlA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4le4 | BETA-GLUCANASE (Podosporaanserina) |
no annotation | 4 | ASN A 182SER A 199ASP A 73SER A 257 | None | 0.95A | 2zw9B-4le4A:undetectable | 2zw9B-4le4A:15.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n8g | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Chromohalobactersalexigens) |
PF03480(DctP) | 4 | ILE A 106SER A 241ASP A 180SER A 95 | NoneDAL A 402 (-2.8A)NoneDAL A 403 ( 4.7A) | 1.03A | 2zw9B-4n8gA:undetectable | 2zw9B-4n8gA:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oya | ADENYLATE CYCLASETYPE 10 (Homo sapiens) |
PF00211(Guanylate_cyc) | 4 | ILE A 407ASN A 412ARG A 176SER A 49 | NoneNone1VE A 501 (-3.2A)None | 1.04A | 2zw9B-4oyaA:undetectable | 2zw9B-4oyaA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pdx | PUTATIVEALKYL/ARYL-SULFATASEYJCS (Escherichiacoli) |
PF00753(Lactamase_B)PF14863(Alkyl_sulf_dimr)PF14864(Alkyl_sulf_C) | 4 | ILE A 396ASN A 394ARG A 477SER A 420 | None | 1.13A | 2zw9B-4pdxA:undetectable | 2zw9B-4pdxA:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rkm | MCCA (Wolinellasuccinogenes) |
no annotation | 4 | ASN A 104SER A 107ARG A 112SER A 120 | None | 1.00A | 2zw9B-4rkmA:undetectable | 2zw9B-4rkmA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tvo | MALATE DEHYDROGENASE (Mycobacteriumtuberculosis) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | ILE A 282ASN A 188SER A 313SER A 284 | None | 1.03A | 2zw9B-4tvoA:4.4 | 2zw9B-4tvoA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzf | FAB FRAGMENT OFIMMUNOGLOBULIN (IGG)MOLECULE (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | ILE E 84SER E 72TYR E 95SER E 19 | None | 1.09A | 2zw9B-4yzfE:undetectable | 2zw9B-4yzfE:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4za2 | 2-DEOXY-D-GLUCONATE3-DEHYDROGENASE (Pectobacteriumcarotovorum) |
PF13561(adh_short_C2) | 4 | ILE A 143ASN A 116SER A 161SER A 145 | None | 1.15A | 2zw9B-4za2A:5.9 | 2zw9B-4za2A:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zo4 | DEPHOSPHO-COA KINASE (Campylobacterjejuni) |
PF01121(CoaE) | 4 | ILE A 21ASN A 23SER A 29SER A 16 | None | 0.99A | 2zw9B-4zo4A:undetectable | 2zw9B-4zo4A:15.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ao8 | SOLUBLE LYTICTRANGLYCOSILASE B3 (Pseudomonasaeruginosa) |
PF01471(PG_binding_1)PF13406(SLT_2) | 4 | ILE A 324ASN A 328ARG A 95SER A 331 | NoneNAG A 999 (-4.0A)NoneNone | 1.12A | 2zw9B-5ao8A:undetectable | 2zw9B-5ao8A:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b4x | REELIN (Mus musculus) |
PF07974(EGF_2) | 4 | ASN A2317SER A2319ASP A2168SER A2222 | NAG A4005 (-1.9A)NAG A4005 (-3.2A)NAG A4005 (-4.0A)None | 1.15A | 2zw9B-5b4xA:undetectable | 2zw9B-5b4xA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cyk | RIBOSOME BIOGENESISPROTEIN YTM1 (Chaetomiumthermophilum) |
PF00400(WD40)PF08154(NLE) | 4 | ILE A 100SER A 403ARG A 419SER A 98 | None | 1.00A | 2zw9B-5cykA:7.9 | 2zw9B-5cykA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e6s | INTEGRIN ALPHA-L (Homo sapiens) |
PF00092(VWA)PF01839(FG-GAP)PF08441(Integrin_alpha2) | 4 | ILE A 126ASN A 129SER A 165ASP A 95 | None | 1.09A | 2zw9B-5e6sA:1.4 | 2zw9B-5e6sA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gwt | 4-HYDROXYISOLECUINEDEHYDROGENASE (Bacillusthuringiensis) |
no annotation | 4 | ILE A 135ASN A 108SER A 153SER A 137 | NAD A 301 (-4.3A)NoneNoneSIN A 302 ( 2.4A) | 1.14A | 2zw9B-5gwtA:5.5 | 2zw9B-5gwtA:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gz4 | SNAKE VENOMPHOSPHODIESTERASE(PDE) (Naja atra) |
PF01033(Somatomedin_B)PF01223(Endonuclease_NS)PF01663(Phosphodiest) | 4 | ILE A 722ASN A 583SER A 579SER A 607 | None | 1.07A | 2zw9B-5gz4A:undetectable | 2zw9B-5gz4A:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ifz | RIBOSE 5-PHOSPHATEISOMERASE (Brucellamelitensis) |
PF02502(LacAB_rpiB) | 4 | ILE A 117ASN A 112SER A 111SER A 104 | None | 1.02A | 2zw9B-5ifzA:undetectable | 2zw9B-5ifzA:12.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jkq | PFVFT1 (Plasmodiumfalciparum) |
no annotation | 4 | ILE A 274SER A 288ASP A 61SER A 272 | None | 1.13A | 2zw9B-5jkqA:undetectable | 2zw9B-5jkqA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k8g | ANTIFREEZE PROTEIN (Marinomonasprimoryensis) |
no annotation | 4 | ILE A 19SER A 107ASP A 16SER A 103 | NoneNone CA A 609 (-2.9A) CA A 610 ( 4.8A) | 1.09A | 2zw9B-5k8gA:undetectable | 2zw9B-5k8gA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m5p | PRE-MRNA-SPLICINGHELICASE BRR2 (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 4 | ILE A1763ASN A1755SER A1854SER A1761 | None | 1.11A | 2zw9B-5m5pA:3.2 | 2zw9B-5m5pA:17.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mln | ALCOHOLDEHYDROGENASE 3 ([Candida]magnoliae) |
no annotation | 4 | ILE A 142ASN A 113SER A 160SER A 144 | NAP A 301 (-4.6A)NoneNoneNAP A 301 (-3.5A) | 1.13A | 2zw9B-5mlnA:5.2 | 2zw9B-5mlnA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o98 | ALCOHOLDEHYDROGENASE 1 (Catharanthusroseus) |
no annotation | 4 | ILE A 165ASN A 139SER A 226SER A 167 | NAP A 501 (-4.4A)NoneNoneNAP A 501 ( 4.3A) | 1.16A | 2zw9B-5o98A:5.5 | 2zw9B-5o98A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t8u | LIPOATE-PROTEINLIGASE 1 (Plasmodiumfalciparum) |
PF03099(BPL_LplA_LipB)PF10437(Lip_prot_lig_C) | 4 | ILE A 32ASN A 29SER A 27SER A 37 | None | 1.14A | 2zw9B-5t8uA:undetectable | 2zw9B-5t8uA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5thw | DEACYLASE (Burkholderiamultivorans) |
PF01546(Peptidase_M20) | 4 | ILE A 137SER A 153ASP A 98SER A 95 | NoneNoneNone ZN A 501 ( 4.9A) | 1.12A | 2zw9B-5thwA:undetectable | 2zw9B-5thwA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tpc | BOTULINUM NEUROTOXINTYPE A (Clostridiumbotulinum) |
PF07951(Toxin_R_bind_C)PF07953(Toxin_R_bind_N) | 4 | ILE A 878ASN A1073SER A 944ASP A 875 | None | 1.12A | 2zw9B-5tpcA:undetectable | 2zw9B-5tpcA:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w11 | GLUCANASE (Thermothelomycesthermophila) |
no annotation | 4 | ILE A 371ASN A 220LYS A 277SER A 418 | None | 1.06A | 2zw9B-5w11A:undetectable | 2zw9B-5w11A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y31 | DISINTEGRIN ANDMETALLOPROTEINASEDOMAIN-CONTAININGPROTEIN 22 (Homo sapiens) |
no annotation | 4 | ILE A 707ASN A 712SER A 689SER A 709 | None | 0.92A | 2zw9B-5y31A:undetectable | 2zw9B-5y31A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ys6 | PRV GLYCOPROTEN B (Suidalphaherpesvirus1) |
no annotation | 4 | ASN A 354ARG A 373TYR A 325SER A 309 | None | 1.15A | 2zw9B-5ys6A:undetectable | 2zw9B-5ys6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z8o | CYCLASE/DEHYDRASE (Mycolicibacteriumsmegmatis) |
no annotation | 4 | ILE A 73ASN A 71TYR A 67SER A 16 | None | 1.11A | 2zw9B-5z8oA:undetectable | 2zw9B-5z8oA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bu3 | BETA-LACTAMASE (Escherichiacoli) |
no annotation | 4 | ILE A 247SER A 130TYR A 264SER A 72 | None3GK A 301 (-2.7A)NoneNone | 0.93A | 2zw9B-6bu3A:undetectable | 2zw9B-6bu3A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d9y | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Paraburkholderiaphymatum) |
no annotation | 4 | ILE A 142ASN A 116SER A 160SER A 144 | None | 1.09A | 2zw9B-6d9yA:6.4 | 2zw9B-6d9yA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f5o | POLYMERASE BASICPROTEIN 2 (Influenza Bvirus) |
no annotation | 4 | ILE C 269SER C 524ASP C 307SER C 520 | None | 1.12A | 2zw9B-6f5oC:undetectable | 2zw9B-6f5oC:undetectable |