SIMILAR PATTERNS OF AMINO ACIDS FOR 2ZUJ_A_CAMA422

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a05 3-ISOPROPYLMALATE
DEHYDROGENASE

(Acidithiobacillus
ferrooxidans) 		PF00180
(Iso_dh) 		4 LEU A 303
VAL A 350
LEU A 354
VAL A 320
 None
 0.85A 2zujA-1a05A:
0.0		 2zujA-1a05A:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a3x PYRUVATE KINASE

(Saccharomyces
cerevisiae) 		PF00224
(PK)
PF02887
(PK_C) 		4 LEU A 163
VAL A 179
LEU A 181
VAL A 145
 None
 0.87A 2zujA-1a3xA:
0.0		 2zujA-1a3xA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1amk TRIOSE PHOSPHATE
ISOMERASE

(Leishmania
mexicana) 		PF00121
(TIM) 		4 VAL A 109
VAL A 162
LEU A 164
VAL A 123
 None
 0.88A 2zujA-1amkA:
0.0		 2zujA-1amkA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1apa POKEWEED ANTIVIRAL
PROTEIN

(Phytolacca
americana) 		PF00161
(RIP) 		4 LEU A  69
VAL A  57
VAL A  13
LEU A 149
 None
 0.88A 2zujA-1apaA:
0.0		 2zujA-1apaA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bvw PROTEIN
(CELLOBIOHYDROLASE
II)

(Humicola
insolens) 		PF01341
(Glyco_hydro_6) 		5 THR A 219
LEU A 221
VAL A 173
LEU A 152
VAL A 144
 None
 1.26A 2zujA-1bvwA:
0.0		 2zujA-1bvwA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c0n PROTEIN (CSDB
PROTEIN)

(Escherichia
coli) 		PF00266
(Aminotran_5) 		4 LEU A 317
VAL A 320
VAL A 347
LEU A 351
 None
 0.89A 2zujA-1c0nA:
0.0		 2zujA-1c0nA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c1f PROTEIN (CONGERIN I)

(Conger
myriaster) 		PF00337
(Gal-bind_lectin) 		4 VAL A  34
VAL A 133
LEU A 135
VAL A  19
 None
 0.74A 2zujA-1c1fA:
undetectable		 2zujA-1c1fA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c30 CARBAMOYL PHOSPHATE
SYNTHETASE: LARGE
SUBUNIT

(Escherichia
coli) 		PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		4 LEU A 623
VAL A 626
VAL A 661
VAL A 638
 None
 0.86A 2zujA-1c30A:
0.0		 2zujA-1c30A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c3c PROTEIN
(ADENYLOSUCCINATE
LYASE)

(Thermotoga
maritima) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		4 LEU A 124
VAL A 127
VAL A 251
VAL A 336
 None
 0.88A 2zujA-1c3cA:
0.0		 2zujA-1c3cA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ch4 MODULE-SUBSTITUTED
CHIMERA HEMOGLOBIN
BETA-ALPHA

(Homo sapiens) 		PF00042
(Globin) 		4 LEU A  68
VAL A  67
VAL A 137
LEU A 134
 None
HEM  A 147 (-4.2A)
None
None
 0.74A 2zujA-1ch4A:
undetectable		 2zujA-1ch4A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1csj HEPATITIS C VIRUS
RNA POLYMERASE
(NS5B)

(Hepacivirus C) 		PF00998
(RdRP_3) 		4 LEU A 384
VAL A 370
VAL A 321
LEU A 314
 None
 0.75A 2zujA-1csjA:
undetectable		 2zujA-1csjA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dab P.69 PERTACTIN

(Bordetella
pertussis) 		PF03212
(Pertactin) 		4 VAL A 186
VAL A 271
LEU A 273
VAL A 217
 None
 0.82A 2zujA-1dabA:
undetectable		 2zujA-1dabA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT

(Rhodobacter
capsulatus) 		PF01078
(Mg_chelatase) 		4 LEU A  65
VAL A  62
VAL A 213
VAL A  50
 None
 0.83A 2zujA-1g8pA:
undetectable		 2zujA-1g8pA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT

(Rhodobacter
capsulatus) 		PF01078
(Mg_chelatase) 		4 THR A  39
VAL A  62
VAL A 213
VAL A  50
 None
 0.73A 2zujA-1g8pA:
undetectable		 2zujA-1g8pA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hbr PROTEIN (HEMOGLOBIN
D)

(Gallus gallus) 		PF00042
(Globin) 		4 LEU A  63
VAL A  62
VAL A 132
LEU A 129
 None
HEM  A 142 ( 4.1A)
None
None
 0.87A 2zujA-1hbrA:
undetectable		 2zujA-1hbrA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1htp H-PROTEIN

(Pisum sativum) 		PF01597
(GCV_H) 		4 PHE A  56
VAL A  41
LEU A  43
VAL A  59
 None
 0.78A 2zujA-1htpA:
undetectable		 2zujA-1htpA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN

(Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF01576
(Myosin_tail_1)
PF02736
(Myosin_N) 		4 LEU S 362
VAL S 359
VAL S 621
LEU S 613
 None
 0.85A 2zujA-1i84S:
undetectable		 2zujA-1i84S:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ibj CYSTATHIONINE
BETA-LYASE

(Arabidopsis
thaliana) 		PF01053
(Cys_Met_Meta_PP) 		4 LEU A 207
VAL A 221
LEU A 223
VAL A 175
 None
 0.87A 2zujA-1ibjA:
undetectable		 2zujA-1ibjA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1idm 3-ISOPROPYLMALATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00180
(Iso_dh) 		4 LEU A 296
VAL A 338
LEU A 342
VAL A 313
 None
 0.83A 2zujA-1idmA:
undetectable		 2zujA-1idmA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jqk CARBON MONOXIDE
DEHYDROGENASE

(Rhodospirillum
rubrum) 		PF03063
(Prismane) 		4 LEU A  84
VAL A 591
VAL A 585
VAL A 615
 None
 0.88A 2zujA-1jqkA:
undetectable		 2zujA-1jqkA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jr6 HELICASE NS3

(Hepacivirus C) 		PF00271
(Helicase_C) 		4 LEU A  30
VAL A  32
VAL A  83
LEU A  51
 None
 0.88A 2zujA-1jr6A:
undetectable		 2zujA-1jr6A:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jzd THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBD

(Escherichia
coli) 		PF11412
(DsbC) 		4 VAL C  98
VAL C  58
LEU C  60
VAL C  85
 None
 0.82A 2zujA-1jzdC:
undetectable		 2zujA-1jzdC:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kqr VP4

(Rotavirus A) 		PF00426
(VP4_haemagglut) 		4 TYR A 165
THR A 176
VAL A 144
LEU A 103
 None
 0.78A 2zujA-1kqrA:
undetectable		 2zujA-1kqrA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mnm PROTEIN (MAT ALPHA-2
TRANSCRIPTIONAL
REPRESSOR)

(Saccharomyces
cerevisiae) 		PF00046
(Homeobox) 		4 PHE C 136
THR C 169
VAL C 180
LEU C 144
 None
 0.81A 2zujA-1mnmC:
undetectable		 2zujA-1mnmC:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n2o PANTOTHENATE
SYNTHETASE

(Mycobacterium
tuberculosis) 		PF02569
(Pantoate_ligase) 		4 LEU A 140
VAL A 143
VAL A 181
VAL A 155
 None
 0.87A 2zujA-1n2oA:
undetectable		 2zujA-1n2oA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o2d ALCOHOL
DEHYDROGENASE,
IRON-CONTAINING

(Thermotoga
maritima) 		PF00465
(Fe-ADH) 		4 TYR A 174
VAL A  91
LEU A  93
VAL A 132
 None
 0.60A 2zujA-1o2dA:
undetectable		 2zujA-1o2dA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oa1 HYDROXYLAMINE
REDUCTASE

(Desulfovibrio
vulgaris) 		PF03063
(Prismane) 		4 LEU A 502
VAL A 526
LEU A 522
VAL A 529
 None
 0.66A 2zujA-1oa1A:
undetectable		 2zujA-1oa1A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q8k EUKARYOTIC
TRANSLATION
INITIATION FACTOR 2
SUBUNIT 1

(Homo sapiens) 		PF00575
(S1)
PF07541
(EIF_2_alpha) 		4 THR A 133
LEU A 111
VAL A 114
LEU A 167
 None
 0.87A 2zujA-1q8kA:
undetectable		 2zujA-1q8kA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6b CLPA PROTEIN

(Escherichia
coli) 		PF00004
(AAA)
PF02861
(Clp_N)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 PHE X 493
LEU X 456
VAL X 560
VAL X 600
 None
 0.70A 2zujA-1r6bX:
undetectable		 2zujA-1r6bX:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ryy ALPHA-AMINO ACID
ESTER HYDROLASE

(Acetobacter
pasteurianus) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C) 		5 PHE A 459
THR A 515
LEU A 518
LEU A 449
VAL A 524
 None
 1.27A 2zujA-1ryyA:
undetectable		 2zujA-1ryyA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t6t PUTATIVE PROTEIN

(Aquifex
aeolicus) 		PF01751
(Toprim) 		4 PHE 1  69
VAL 1  54
VAL 1  93
VAL 1  65
 None
 0.80A 2zujA-1t6t1:
undetectable		 2zujA-1t6t1:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ufr PYR MRNA-BINDING
ATTENUATION PROTEIN

(Thermus
thermophilus) 		PF00156
(Pribosyltran) 		4 THR A 154
VAL A 105
LEU A 175
VAL A 173
 None
 0.81A 2zujA-1ufrA:
undetectable		 2zujA-1ufrA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1upx HYDROXYLAMINE
REDUCTASE

(Desulfovibrio
desulfuricans) 		PF03063
(Prismane) 		4 LEU A 495
VAL A 519
LEU A 515
VAL A 522
 None
 0.74A 2zujA-1upxA:
undetectable		 2zujA-1upxA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v72 ALDOLASE

(Pseudomonas
putida) 		PF01212
(Beta_elim_lyase) 		5 PHE A 328
LEU A 343
VAL A 346
VAL A 288
LEU A 297
 None
 1.23A 2zujA-1v72A:
undetectable		 2zujA-1v72A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9j BOLA-LIKE PROTEIN
RIKEN CDNA
1110025L05

(Mus musculus) 		PF01722
(BolA) 		4 LEU A  87
VAL A  83
VAL A  48
VAL A  66
 None
 0.61A 2zujA-1v9jA:
undetectable		 2zujA-1v9jA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wgv KIAA1068 PROTEIN

(Homo sapiens) 		PF04969
(CS) 		4 VAL A  33
VAL A  49
LEU A  51
VAL A  58
 None
 0.73A 2zujA-1wgvA:
undetectable		 2zujA-1wgvA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1whx HYPOTHETICAL PROTEIN
RIKEN CDNA
1200009A02

(Mus musculus) 		PF00076
(RRM_1) 		4 THR A 233
VAL A 251
LEU A 253
VAL A 262
 None
 0.79A 2zujA-1whxA:
undetectable		 2zujA-1whxA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wkp FLOWERING LOCUS T
PROTEIN

(Arabidopsis
thaliana) 		PF01161
(PBP) 		5 PHE A  22
LEU A  28
VAL A  14
LEU A   9
VAL A  18
 None
 1.25A 2zujA-1wkpA:
undetectable		 2zujA-1wkpA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x0l HOMOISOCITRATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00180
(Iso_dh) 		4 LEU A 285
VAL A 327
LEU A 331
VAL A 301
 None
 0.87A 2zujA-1x0lA:
undetectable		 2zujA-1x0lA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yaa ASPARTATE
AMINOTRANSFERASE

(Saccharomyces
cerevisiae) 		PF00155
(Aminotran_1_2) 		4 LEU A 337
VAL A 379
LEU A 381
VAL A  33
 None
 0.85A 2zujA-1yaaA:
undetectable		 2zujA-1yaaA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yaa ASPARTATE
AMINOTRANSFERASE

(Saccharomyces
cerevisiae) 		PF00155
(Aminotran_1_2) 		4 THR A 363
VAL A 379
LEU A 381
VAL A  33
 None
 0.77A 2zujA-1yaaA:
undetectable		 2zujA-1yaaA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ybm UNKNOWN PROTEIN
AT5G02240

(Arabidopsis
thaliana) 		PF13460
(NAD_binding_10) 		4 VAL A 211
VAL A  74
LEU A  76
VAL A 129
 None
 0.75A 2zujA-1ybmA:
undetectable		 2zujA-1ybmA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ygp YEAST GLYCOGEN
PHOSPHORYLASE

(Saccharomyces
cerevisiae) 		PF00343
(Phosphorylase) 		4 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.73A 2zujA-1ygpA:
undetectable		 2zujA-1ygpA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ykw RUBISCO-LIKE PROTEIN

(Chlorobaculum
tepidum) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		5 PHE A 137
TYR A 141
VAL A 116
LEU A 313
VAL A 306
 None
 1.15A 2zujA-1ykwA:
undetectable		 2zujA-1ykwA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zuo HYPOTHETICAL PROTEIN
LOC92912

(Homo sapiens) 		PF00179
(UQ_con) 		4 PHE A 274
VAL A 322
VAL A 229
VAL A 241
 None
 0.84A 2zujA-1zuoA:
undetectable		 2zujA-1zuoA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2azk GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE

(Sulfolobus
solfataricus) 		PF00348
(polyprenyl_synt) 		4 PHE A 253
THR A 181
VAL A 188
LEU A  56
 None
 0.79A 2zujA-2azkA:
undetectable		 2zujA-2azkA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b39 C3

(Bos taurus) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		4 THR A1323
VAL A1343
LEU A1299
VAL A1331
 None
 0.76A 2zujA-2b39A:
undetectable		 2zujA-2b39A:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b3d MODULATOR OF DRUG
ACTIVITY B

(Escherichia
coli) 		PF02525
(Flavodoxin_2) 		5 PHE A  97
LEU A  16
VAL A  74
VAL A 125
LEU A 104
 None
 1.27A 2zujA-2b3dA:
undetectable		 2zujA-2b3dA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cjs UNC-13 HOMOLOG A

(Rattus
norvegicus) 		PF00168
(C2) 		4 VAL A   8
VAL A  78
LEU A  99
VAL A  62
 None
 0.84A 2zujA-2cjsA:
undetectable		 2zujA-2cjsA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cph RNA BINDING MOTIF
PROTEIN 19

(Mus musculus) 		PF00076
(RRM_1) 		4 LEU A 530
VAL A 491
LEU A 493
VAL A 509
 None
 0.83A 2zujA-2cphA:
undetectable		 2zujA-2cphA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cqz 177AA LONG
HYPOTHETICAL PROTEIN

(Pyrococcus
horikoshii) 		PF13023
(HD_3) 		4 LEU A  11
VAL A   8
VAL A  94
VAL A  98
 None
 0.87A 2zujA-2cqzA:
undetectable		 2zujA-2cqzA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d90 PDZ DOMAIN
CONTAINING PROTEIN 1

(Mus musculus) 		PF00595
(PDZ) 		5 PHE A  21
TYR A  19
THR A  81
VAL A  54
LEU A  83
 None
 1.13A 2zujA-2d90A:
undetectable		 2zujA-2d90A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dfu PROBABLE
2-HYDROXYHEPTA-2,4-D
IENE-1,7-DIOATE
ISOMERASE

(Thermus
thermophilus) 		PF01557
(FAA_hydrolase)
PF10370
(DUF2437) 		4 LEU A 252
VAL A 224
LEU A 226
VAL A 120
 None
 0.86A 2zujA-2dfuA:
undetectable		 2zujA-2dfuA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dgk GLUTAMATE
DECARBOXYLASE BETA

(Escherichia
coli) 		PF00282
(Pyridoxal_deC) 		5 PHE A 380
TYR A 363
LEU A 445
LEU A 392
VAL A 406
 None
 1.04A 2zujA-2dgkA:
undetectable		 2zujA-2dgkA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dgk GLUTAMATE
DECARBOXYLASE BETA

(Escherichia
coli) 		PF00282
(Pyridoxal_deC) 		5 PHE A 429
LEU A 399
VAL A 406
VAL A 378
LEU A 353
 None
 1.49A 2zujA-2dgkA:
undetectable		 2zujA-2dgkA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dj6 HYPOTHETICAL PROTEIN
PH0634

(Pyrococcus
horikoshii) 		PF01242
(PTPS) 		4 LEU A  63
VAL A 101
LEU A 103
VAL A  35
 LEU  A  63 ( 0.5A)
VAL  A 101 ( 0.6A)
LEU  A 103 ( 0.6A)
VAL  A  35 ( 0.6A)
 0.87A 2zujA-2dj6A:
undetectable		 2zujA-2dj6A:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e7u GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE

(Thermus
thermophilus) 		PF00202
(Aminotran_3) 		5 TYR A  57
THR A 416
LEU A 387
LEU A 333
VAL A 350
 None
 1.35A 2zujA-2e7uA:
undetectable		 2zujA-2e7uA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e7z ACETYLENE HYDRATASE
AHY

(Pelobacter
acetylenicus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		5 PHE A 398
TYR A 423
THR A 135
VAL A 409
LEU A 397
 None
 1.37A 2zujA-2e7zA:
undetectable		 2zujA-2e7zA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fi1 HYDROLASE, HALOACID
DEHALOGENASE-LIKE
FAMILY

(Streptococcus
pneumoniae) 		PF13419
(HAD_2) 		5 PHE A  66
TYR A  70
THR A  52
LEU A  48
VAL A  44
 None
 1.49A 2zujA-2fi1A:
undetectable		 2zujA-2fi1A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h0a TRANSCRIPTIONAL
REGULATOR

(Thermus
thermophilus) 		PF13377
(Peripla_BP_3) 		4 LEU A 266
VAL A 248
LEU A 246
VAL A 276
 None
 0.83A 2zujA-2h0aA:
undetectable		 2zujA-2h0aA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hpi DNA POLYMERASE III
ALPHA SUBUNIT

(Thermus
aquaticus) 		PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		5 TYR A 604
LEU A  50
VAL A 110
VAL A 283
LEU A 285
 None
 1.43A 2zujA-2hpiA:
undetectable		 2zujA-2hpiA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2htm PUTATIVE THIAMINE
BIOSYNTHESIS PROTEIN
THIS

(Thermus
thermophilus) 		PF02597
(ThiS) 		4 VAL E  19
VAL E  32
LEU E  34
VAL E  57
 None
 0.70A 2zujA-2htmE:
undetectable		 2zujA-2htmE:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hxr HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CYNR

(Escherichia
coli) 		PF03466
(LysR_substrate) 		5 THR A 200
LEU A 194
VAL A 227
LEU A 165
VAL A 168
 None
 1.11A 2zujA-2hxrA:
undetectable		 2zujA-2hxrA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iou PERTACTIN
EXTRACELLULAR DOMAIN

(Bordetella
bronchiseptica) 		PF03212
(Pertactin) 		4 VAL G 223
VAL G 303
LEU G 305
VAL G 254
 None
 0.84A 2zujA-2iouG:
undetectable		 2zujA-2iouG:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jqz E3 UBIQUITIN-PROTEIN
LIGASE SMURF2

(Homo sapiens) 		PF00168
(C2) 		4 VAL A  39
VAL A 134
LEU A 136
VAL A  18
 None
 0.77A 2zujA-2jqzA:
undetectable		 2zujA-2jqzA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2knb E3 UBIQUITIN-PROTEIN
LIGASE PARKIN

(Rattus
norvegicus) 		PF00240
(ubiquitin) 		4 THR A  21
VAL A  29
VAL A  67
VAL A   5
 None
 0.88A 2zujA-2knbA:
undetectable		 2zujA-2knbA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lhh CALMODULIN

(Saccharomyces
cerevisiae) 		PF00036
(EF-hand_1)
PF13499
(EF-hand_7) 		4 LEU A  32
VAL A  35
VAL A 108
LEU A 105
 None
 0.69A 2zujA-2lhhA:
undetectable		 2zujA-2lhhA:
15.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		5 PHE A  87
TYR A  96
LEU A 244
VAL A 247
VAL A 396
 CAM  A 502 (-4.6A)
CAM  A 502 (-4.5A)
HEM  A 501 (-4.5A)
None
None
 1.09A 2zujA-2m56A:
69.1		 2zujA-2m56A:
99.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		7 PHE A  87
TYR A  96
THR A 101
LEU A 244
VAL A 247
VAL A 295
VAL A 396
 CAM  A 502 (-4.6A)
CAM  A 502 (-4.5A)
HEM  A 501 (-2.9A)
HEM  A 501 (-4.5A)
None
HEM  A 501 (-4.6A)
None
 0.45A 2zujA-2m56A:
69.1		 2zujA-2m56A:
99.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		5 PHE A  87
TYR A  96
THR A 101
LEU A 244
VAL A 295
 CAM  A 502 (-4.6A)
CAM  A 502 (-4.5A)
HEM  A 501 (-2.9A)
HEM  A 501 (-4.5A)
HEM  A 501 (-4.6A)
 0.88A 2zujA-2m56A:
69.1		 2zujA-2m56A:
99.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mks RNA-BINDING MOTIF
PROTEIN, X
CHROMOSOME

(Homo sapiens) 		PF00076
(RRM_1) 		5 THR A  21
VAL A  29
VAL A  39
LEU A  41
VAL A  56
 None
 1.03A 2zujA-2mksA:
undetectable		 2zujA-2mksA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nvo RO SIXTY-RELATED
PROTEIN, RSR

(Deinococcus
radiodurans) 		PF05731
(TROVE) 		4 LEU A 313
VAL A 492
LEU A 494
VAL A 512
 None
 0.83A 2zujA-2nvoA:
undetectable		 2zujA-2nvoA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2odl ADHESIN

(Haemophilus
influenzae) 		PF05860
(Haemagg_act) 		4 LEU A  71
VAL A 146
LEU A 148
VAL A 124
 None
 0.68A 2zujA-2odlA:
undetectable		 2zujA-2odlA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p3j VP4

(Rotavirus A) 		PF00426
(VP4_haemagglut) 		4 TYR A 165
THR A 176
VAL A 144
LEU A 103
 None
 0.87A 2zujA-2p3jA:
undetectable		 2zujA-2p3jA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p8u HYDROXYMETHYLGLUTARY
L-COA SYNTHASE,
CYTOPLASMIC

(Homo sapiens) 		PF01154
(HMG_CoA_synt_N)
PF08540
(HMG_CoA_synt_C) 		4 PHE A 189
LEU A 179
VAL A 372
LEU A 386
 None
 0.88A 2zujA-2p8uA:
undetectable		 2zujA-2p8uA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pbk KSHV PROTEASE

(Human
gammaherpesvirus
8) 		PF00716
(Peptidase_S21) 		4 LEU A  34
VAL A  36
VAL A 135
LEU A 115
 None
 0.77A 2zujA-2pbkA:
undetectable		 2zujA-2pbkA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pr5 BLUE-LIGHT
PHOTORECEPTOR

(Bacillus
subtilis) 		PF13426
(PAS_9) 		4 PHE A  64
THR A  50
VAL A  42
LEU A  65
 None
None
None
FMN  A 500 (-4.4A)
 0.82A 2zujA-2pr5A:
undetectable		 2zujA-2pr5A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q2v BETA-D-HYDROXYBUTYRA
TE DEHYDROGENASE

(Pseudomonas
putida) 		PF00106
(adh_short) 		4 LEU A 112
VAL A 115
VAL A 165
VAL A 166
 None
 0.77A 2zujA-2q2vA:
undetectable		 2zujA-2q2vA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qgx UBIQUITIN-CONJUGATIN
G ENZYME E2 Q1

(Homo sapiens) 		PF00179
(UQ_con) 		4 PHE A  74
VAL A 122
VAL A  29
VAL A  41
 None
 0.63A 2zujA-2qgxA:
undetectable		 2zujA-2qgxA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qgy ENOLASE FROM THE
ENVIRONMENTAL GENOME
SHOTGUN SEQUENCING
OF THE SARGASSO SEA

(-) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 THR A 148
LEU A 152
VAL A 185
LEU A 172
 None
 0.83A 2zujA-2qgyA:
undetectable		 2zujA-2qgyA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qkx BIFUNCTIONAL PROTEIN
GLMU

(Mycobacterium
tuberculosis) 		PF00132
(Hexapep)
PF12804
(NTP_transf_3) 		4 LEU A  28
VAL A  54
LEU A  56
VAL A  11
 None
 0.84A 2zujA-2qkxA:
undetectable		 2zujA-2qkxA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qzp ACYLAMINO-ACID-RELEA
SING ENZYME

(Aeropyrum
pernix) 		PF00326
(Peptidase_S9) 		4 TYR A 444
LEU A 568
VAL A 363
LEU A 365
 None
 0.81A 2zujA-2qzpA:
undetectable		 2zujA-2qzpA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qzp ACYLAMINO-ACID-RELEA
SING ENZYME

(Aeropyrum
pernix) 		PF00326
(Peptidase_S9) 		4 TYR A 444
LEU A 568
VAL A 392
VAL A 363
 None
 0.88A 2zujA-2qzpA:
undetectable		 2zujA-2qzpA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r8r SENSOR PROTEIN

(Pseudomonas
syringae group
genomosp. 3) 		PF02702
(KdpD) 		4 THR A 204
LEU A   8
VAL A 121
LEU A 129
 None
 0.76A 2zujA-2r8rA:
undetectable		 2zujA-2r8rA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rrb CDNA FLJ40872 FIS,
CLONE TUTER2000283,
HIGHLY SIMILAR TO
HOMO SAPIENS
TRANSFORMER-2-BETA
(SFRS10) GENE

(Homo sapiens) 		PF00076
(RRM_1) 		4 THR A 129
LEU A 184
VAL A 147
VAL A 164
 None
 0.71A 2zujA-2rrbA:
undetectable		 2zujA-2rrbA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rv9 GLUCANASE

(Paenibacillus
fukuinensis) 		PF00754
(F5_F8_type_C) 		4 VAL A  45
VAL A  56
LEU A  58
VAL A 128
 None
 0.86A 2zujA-2rv9A:
undetectable		 2zujA-2rv9A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v5o CATION-INDEPENDENT
MANNOSE-6-PHOSPHATE
RECEPTOR

(Homo sapiens) 		PF00040
(fn2)
PF00878
(CIMR) 		4 THR A1983
VAL A1883
VAL A1838
LEU A1820
 None
 0.80A 2zujA-2v5oA:
undetectable		 2zujA-2v5oA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v5p CATION-INDEPENDENT
MANNOSE-6-PHOSPHATE
RECEPTOR

(Homo sapiens) 		PF00040
(fn2)
PF00878
(CIMR) 		4 THR A1983
VAL A1883
VAL A1838
LEU A1820
 None
 0.77A 2zujA-2v5pA:
undetectable		 2zujA-2v5pA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xwb COMPLEMENT C3B
ALPHA' CHAIN

(Homo sapiens) 		PF00207
(A2M)
PF01759
(NTR)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 THR B1302
VAL B1322
LEU B1278
VAL B1310
 None
 0.84A 2zujA-2xwbB:
undetectable		 2zujA-2xwbB:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xym RNA-DIRECTED RNA
POLYMERASE

(Hepacivirus C) 		PF00998
(RdRP_3) 		4 LEU A 384
VAL A 370
VAL A 321
LEU A 314
 None
 0.79A 2zujA-2xymA:
undetectable		 2zujA-2xymA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yz2 PUTATIVE ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0222

(Thermotoga
maritima) 		PF00005
(ABC_tran) 		4 LEU A  23
VAL A  26
VAL A  38
VAL A 209
 None
 0.83A 2zujA-2yz2A:
undetectable		 2zujA-2yz2A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z1a 5'-NUCLEOTIDASE

(Thermus
thermophilus) 		PF00149
(Metallophos)
PF02872
(5_nucleotid_C) 		4 PHE A 288
LEU A 284
LEU A 294
VAL A 231
 None
 0.81A 2zujA-2z1aA:
undetectable		 2zujA-2z1aA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a1n NDP-SUGAR EPIMERASE

(Thermoplasma
volcanium) 		PF01370
(Epimerase) 		5 TYR A 164
LEU A 214
VAL A 218
VAL A   4
LEU A  69
 None
None
None
None
NAD  A3001 (-4.6A)
 1.45A 2zujA-3a1nA:
undetectable		 2zujA-3a1nA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aiz DNA POLYMERASE
SLIDING CLAMP B

(Sulfurisphaera
tokodaii) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 LEU A 205
VAL A 208
VAL A 218
VAL A 232
 None
 0.80A 2zujA-3aizA:
undetectable		 2zujA-3aizA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ajy ANCESTRAL CONGERIN
CON-ANC

(-) 		PF00337
(Gal-bind_lectin) 		4 VAL A  34
VAL A 131
LEU A 133
VAL A  19
 None
 0.74A 2zujA-3ajyA:
undetectable		 2zujA-3ajyA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ajz ANCESTRAL CONGERIN
CON-ANC

(-) 		PF00337
(Gal-bind_lectin) 		4 VAL A  32
VAL A 129
LEU A 131
VAL A  17
 None
 0.73A 2zujA-3ajzA:
undetectable		 2zujA-3ajzA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3at6 ALPHAA-GLOBIN

(Podocnemis
unifilis) 		PF00042
(Globin) 		4 LEU A  63
VAL A  62
VAL A 132
LEU A 129
 None
HEM  A 142 (-3.8A)
None
None
 0.76A 2zujA-3at6A:
undetectable		 2zujA-3at6A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ay3 NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E

(Chromohalobacter
salexigens) 		PF01370
(Epimerase) 		4 THR A   8
LEU A   6
VAL A  61
LEU A  51
 None
 0.86A 2zujA-3ay3A:
undetectable		 2zujA-3ay3A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b8y ENDO-PECTATE LYASE

(Dickeya
chrysanthemi) 		PF03211
(Pectate_lyase) 		4 VAL A 225
VAL A 268
LEU A 296
VAL A 237
 None
 0.88A 2zujA-3b8yA:
undetectable		 2zujA-3b8yA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus) 		PF03069
(FmdA_AmdA) 		4 TYR A 227
LEU A 279
VAL A 278
VAL A 223
 None
 0.89A 2zujA-3b9tA:
undetectable		 2zujA-3b9tA:
22.22