SIMILAR PATTERNS OF AMINO ACIDS FOR 2ZJ0_B_2FAB500_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d0n | HORSE PLASMAGELSOLIN (Equus caballus) |
PF00626(Gelsolin) | 4 | LEU A 71GLN A 82THR A 73THR A 105 | None | 1.06A | 2zj0B-1d0nA:undetectable | 2zj0B-1d0nA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ddk | IMP-1 METALLOBETA-LACTAMASE (Pseudomonasaeruginosa) |
PF00753(Lactamase_B) | 4 | GLN A 212THR A 209THR A 140HIS A 77 | NoneNoneNone ZN A 500 (-3.4A) | 1.15A | 2zj0B-1ddkA:3.1 | 2zj0B-1ddkA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e1c | METHYLMALONYL-COAMUTASE ALPHA CHAIN (Propionibacteriumfreudenreichii) |
PF01642(MM_CoA_mutase)PF02310(B12-binding) | 4 | LEU A 668GLN A 643THR A 640THR A 683 | NoneNoneNoneB12 A 800 ( 4.9A) | 1.30A | 2zj0B-1e1cA:4.3 | 2zj0B-1e1cA:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ii0 | ARSENICALPUMP-DRIVING ATPASE (Escherichiacoli) |
PF02374(ArsA_ATPase) | 4 | GLN A 430THR A 480THR A 451HIS A 453 | NoneNoneNone CD A 595 ( 3.5A) | 1.33A | 2zj0B-1ii0A:2.4 | 2zj0B-1ii0A:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lox | 15-LIPOXYGENASE (Oryctolaguscuniculus) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | LEU A 549GLN A 590THR A 553HIS A 545 | NoneNoneNoneFE2 A 840 (-3.3A) | 1.28A | 2zj0B-1loxA:undetectable | 2zj0B-1loxA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n11 | ANKYRIN (Homo sapiens) |
PF00023(Ank)PF12796(Ank_2)PF13637(Ank_4)PF13857(Ank_5) | 4 | LEU A 474GLN A 471THR A 472THR A 518 | None | 1.29A | 2zj0B-1n11A:undetectable | 2zj0B-1n11A:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n5x | XANTHINEDEHYDROGENASE (Bos taurus) |
PF00111(Fer2)PF00941(FAD_binding_5)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2)PF03450(CO_deh_flav_C) | 4 | LEU A 873GLN A 767THR A 803THR A1010 | TEI A3006 (-4.8A)MOS A3004 (-3.8A)NoneTEI A3006 (-2.8A) | 1.07A | 2zj0B-1n5xA:undetectable | 2zj0B-1n5xA:17.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o7l | TRANSCRIPTIONALREGULATOR MODE (Escherichiacoli) |
PF00126(HTH_1)PF03459(TOBE) | 4 | LEU A 181GLN A 124THR A 125THR A 260 | None | 1.30A | 2zj0B-1o7lA:undetectable | 2zj0B-1o7lA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r6v | SUBTILISIN-LIKESERINE PROTEASE (Fervidobacteriumpennivorans) |
PF00082(Peptidase_S8) | 4 | LEU A 577GLN A 618THR A 619THR A 572 | None | 1.34A | 2zj0B-1r6vA:2.9 | 2zj0B-1r6vA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rgi | GELSOLIN (Equus caballus) |
PF00626(Gelsolin) | 4 | LEU G 71GLN G 82THR G 73THR G 105 | None | 1.05A | 2zj0B-1rgiG:undetectable | 2zj0B-1rgiG:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t44 | CHIMERA OF GELSOLINDOMAIN 1 ANDC-TERMINAL DOMAIN OFTHYMOSIN BETA-4 (Homo sapiens;Mus musculus) |
PF00626(Gelsolin)PF01290(Thymosin) | 4 | LEU G 71GLN G 82THR G 73THR G 105 | None | 1.05A | 2zj0B-1t44G:undetectable | 2zj0B-1t44G:13.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xea | OXIDOREDUCTASE,GFO/IDH/MOCA FAMILY (Vibrio cholerae) |
PF01408(GFO_IDH_MocA) | 4 | LEU A 144GLN A 205THR A 209THR A 227 | None | 1.25A | 2zj0B-1xeaA:6.1 | 2zj0B-1xeaA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yt3 | RIBONUCLEASE D (Escherichiacoli) |
PF00570(HRDC)PF01612(DNA_pol_A_exo1) | 4 | LEU A 290GLN A 213THR A 211THR A 284 | None | 1.24A | 2zj0B-1yt3A:undetectable | 2zj0B-1yt3A:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c4k | PHOSPHORIBOSYLPYROPHOSPHATESYNTHETASE-ASSOCIATED PROTEIN 1 (Homo sapiens) |
PF13793(Pribosyltran_N)PF14572(Pribosyl_synth) | 4 | LEU A 22GLN A 64THR A 65THR A 27 | None | 1.12A | 2zj0B-2c4kA:2.7 | 2zj0B-2c4kA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ff6 | GELSOLIN (Homo sapiens) |
PF00626(Gelsolin) | 4 | LEU G 71GLN G 82THR G 73THR G 105 | None | 1.04A | 2zj0B-2ff6G:undetectable | 2zj0B-2ff6G:14.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ice | COMPLEMENT C3 BETACHAIN (Homo sapiens) |
PF01835(A2M_N)PF07703(A2M_N_2) | 4 | GLN A 631THR A 632THR A 514HIS A 25 | None | 0.97A | 2zj0B-2iceA:undetectable | 2zj0B-2iceA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kbb | TALIN-1 (Mus musculus) |
no annotation | 4 | LEU A1741GLN A1764THR A1765THR A1704 | None | 1.01A | 2zj0B-2kbbA:undetectable | 2zj0B-2kbbA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nlz | CEPHALOSPORINACYLASE (Bacillushalodurans) |
PF01019(G_glu_transpept) | 4 | LEU A 208GLN A 375THR A 56THR A 390 | None | 1.06A | 2zj0B-2nlzA:undetectable | 2zj0B-2nlzA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nvv | ACETYL-COAHYDROLASE/TRANSFERASE FAMILY PROTEIN (Porphyromonasgingivalis) |
PF02550(AcetylCoA_hydro)PF13336(AcetylCoA_hyd_C) | 4 | GLN A 333THR A 107THR A 383HIS A 414 | GLN A 333 ( 0.6A)THR A 107 ( 0.8A)THR A 383 ( 0.8A)HIS A 414 ( 1.0A) | 0.99A | 2zj0B-2nvvA:2.2 | 2zj0B-2nvvA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o26 | MAST/STEM CELLGROWTH FACTORRECEPTOR (Mus musculus) |
no annotation | 4 | GLN X 275THR X 277THR X 306HIS X 222 | None | 1.34A | 2zj0B-2o26X:undetectable | 2zj0B-2o26X:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2okc | TYPE I RESTRICTIONENZYME STYSJI MPROTEIN (Bacteroidesthetaiotaomicron) |
PF02384(N6_Mtase)PF12161(HsdM_N) | 4 | LEU A 18GLN A 25THR A 21THR A 115 | None | 1.30A | 2zj0B-2okcA:4.4 | 2zj0B-2okcA:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2om6 | PROBABLEPHOSPHOSERINEPHOSPHATASE (Pyrococcushorikoshii) |
PF13419(HAD_2) | 4 | LEU A 15THR A 104THR A 8HIS A 180 | None | 1.01A | 2zj0B-2om6A:3.5 | 2zj0B-2om6A:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p14 | HETERODIMERICRESTRICTIONENDONUCLEASER.BSPD6I SMALLSUBUNIT (Bacillus sp. D6) |
PF09491(RE_AlwI) | 4 | LEU A 5GLN A 144THR A 143THR A 25 | None | 1.15A | 2zj0B-2p14A:3.0 | 2zj0B-2p14A:15.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r1f | PREDICTEDAMINODEOXYCHORISMATELYASE (Escherichiacoli) |
PF02618(YceG) | 4 | LEU A 137GLN A 147THR A 144THR A 173 | None | 1.11A | 2zj0B-2r1fA:undetectable | 2zj0B-2r1fA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wlv | GAG POLYPROTEIN (Humanimmunodeficiencyvirus 2) |
PF00607(Gag_p24) | 4 | LEU B 14THR B 18THR B 47HIS B 11 | None | 1.20A | 2zj0B-2wlvB:undetectable | 2zj0B-2wlvB:13.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y7c | TYPE I RESTRICTIONENZYME ECOKI MPROTEIN (Escherichiacoli) |
PF02384(N6_Mtase)PF12161(HsdM_N) | 4 | LEU B 163GLN B 166THR B 358HIS B 335 | None | 1.25A | 2zj0B-2y7cB:3.9 | 2zj0B-2y7cB:23.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yet | GH61 ISOZYME A (Thermoascusaurantiacus) |
PF03443(Glyco_hydro_61) | 4 | LEU A 41GLN A 5THR A 36HIS A 57 | HIC A 1 ( 4.9A)NoneNoneNone | 1.30A | 2zj0B-2yetA:undetectable | 2zj0B-2yetA:18.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ypf | AVRBS3 (Xanthomonascampestris) |
PF03377(TAL_effector) | 4 | LEU A 545GLN A 515THR A 513HIS A 525 | None | 1.11A | 2zj0B-2ypfA:undetectable | 2zj0B-2ypfA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ypf | AVRBS3 (Xanthomonascampestris) |
PF03377(TAL_effector) | 4 | LEU A 647GLN A 617THR A 615HIS A 627 | None | 1.27A | 2zj0B-2ypfA:undetectable | 2zj0B-2ypfA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bq3 | DEFECTIVE IN CULLINNEDDYLATION PROTEIN1 (Saccharomycescerevisiae) |
PF03556(Cullin_binding)PF14555(UBA_4) | 4 | LEU A 116GLN A 137THR A 133THR A 109 | None | 1.20A | 2zj0B-3bq3A:undetectable | 2zj0B-3bq3A:18.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ce6 | ADENOSYLHOMOCYSTEINASE (Mycobacteriumtuberculosis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | LEU A 68GLN A 73THR A 74THR A 219HIS A 363 | NoneADN A 500 (-3.6A)ADN A 500 (-4.5A)NAD A 550 ( 2.8A)ADN A 500 ( 3.7A) | 0.29A | 2zj0B-3ce6A:66.7 | 2zj0B-3ce6A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cjp | PREDICTEDAMIDOHYDROLASE,DIHYDROOROTASEFAMILY (Clostridiumacetobutylicum) |
PF04909(Amidohydro_2) | 4 | LEU A 32THR A 30THR A 35HIS A 38 | None | 1.32A | 2zj0B-3cjpA:undetectable | 2zj0B-3cjpA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3db2 | PUTATIVENADPH-DEPENDENTOXIDOREDUCTASE (Desulfitobacteriumhafniense) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | LEU A 178GLN A 217THR A 232HIS A 341 | None | 1.19A | 2zj0B-3db2A:2.6 | 2zj0B-3db2A:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dbo | UNCHARACTERIZEDPROTEIN (Mycobacteriumtuberculosis) |
PF01850(PIN)PF02604(PhdYeFM_antitox) | 4 | LEU B 58GLN A 69THR B 77THR B 51 | NoneNoneNone NA B 301 (-2.8A) | 1.28A | 2zj0B-3dboB:undetectable | 2zj0B-3dboB:15.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ed0 | (3R)-HYDROXYMYRISTOYL-ACYL CARRIERPROTEIN DEHYDRATASE (Helicobacterpylori) |
PF07977(FabA) | 4 | LEU A 119GLN A 76THR A 138HIS A 122 | None | 1.28A | 2zj0B-3ed0A:undetectable | 2zj0B-3ed0A:15.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3faw | RETICULOCYTE BINDINGPROTEIN (Streptococcusagalactiae) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 4 | LEU A 946GLN A1036THR A1035THR A 922 | NoneNoneNone CL A1223 (-4.3A) | 1.33A | 2zj0B-3fawA:undetectable | 2zj0B-3fawA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fd5 | SELENIDE, WATERDIKINASE 1 (Homo sapiens) |
PF00586(AIRS)PF02769(AIRS_C) | 4 | LEU A 324THR A 200THR A 117HIS A 256 | None | 1.28A | 2zj0B-3fd5A:undetectable | 2zj0B-3fd5A:22.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3g1u | ADENOSYLHOMOCYSTEINASE (Leishmaniamajor) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | LEU A 51GLN A 56THR A 57THR A 156HIS A 300 | NoneADN A 438 (-3.8A)ADN A 438 (-4.6A)NAD A 439 ( 3.0A)ADN A 438 ( 4.0A) | 0.34A | 2zj0B-3g1uA:53.5 | 2zj0B-3g1uA:54.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gem | SHORT CHAINDEHYDROGENASE (Pseudomonassavastanoi) |
PF13561(adh_short_C2) | 4 | LEU A 78THR A 75THR A 11HIS A 83 | None | 1.31A | 2zj0B-3gemA:7.6 | 2zj0B-3gemA:17.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3glq | ADENOSYLHOMOCYSTEINASE (Burkholderiapseudomallei) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | LEU A 61GLN A 66THR A 67THR A 200HIS A 344 | NoneRAB A 602 (-3.9A)RAB A 602 (-4.5A)NAD A 601 ( 2.9A)RAB A 602 ( 3.5A) | 0.34A | 2zj0B-3glqA:58.7 | 2zj0B-3glqA:57.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gwj | ARYLPHORIN (Antheraeapernyi) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 4 | LEU A 290GLN A 404THR A 405THR A 161 | None | 1.09A | 2zj0B-3gwjA:undetectable | 2zj0B-3gwjA:21.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3h9u | ADENOSYLHOMOCYSTEINASE (Trypanosomabrucei) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | LEU A 51GLN A 56THR A 57THR A 156HIS A 300 | NoneADN A 439 (-3.6A)ADN A 439 (-4.7A)NAD A 438 (-3.8A)None | 0.51A | 2zj0B-3h9uA:55.6 | 2zj0B-3h9uA:56.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3il4 | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 (Enterococcusfaecalis) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 4 | LEU A 301THR A 14THR A 324HIS A 178 | NoneCSO A 13 ( 3.6A)NoneNone | 1.31A | 2zj0B-3il4A:2.1 | 2zj0B-3il4A:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb9 | PRE-MRNA-SPLICINGFACTOR CWF11 (Schizosaccharomycespombe) |
PF13087(AAA_12)PF16399(Aquarius_N) | 4 | LEU X 690THR X 692THR X 701HIS X 716 | None | 1.28A | 2zj0B-3jb9X:undetectable | 2zj0B-3jb9X:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lfu | DNA HELICASE II (Escherichiacoli) |
PF00580(UvrD-helicase)PF13361(UvrD_C) | 4 | LEU A 512GLN A 480THR A 481HIS A 537 | None | 1.22A | 2zj0B-3lfuA:undetectable | 2zj0B-3lfuA:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m6i | L-ARABINITOL4-DEHYDROGENASE (Neurosporacrassa) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | LEU A 137THR A 50THR A 14HIS A 74 | None | 1.25A | 2zj0B-3m6iA:9.9 | 2zj0B-3m6iA:22.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3n58 | ADENOSYLHOMOCYSTEINASE (Brucellaabortus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | LEU A 54GLN A 59THR A 60THR A 193HIS A 337 | None K A 2 ( 3.3A)ADN A 500 (-4.6A)NAD A 550 ( 3.0A)ADN A 500 ( 3.6A) | 0.42A | 2zj0B-3n58A:58.7 | 2zj0B-3n58A:60.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o6b | DEFECTIVE IN CULLINNEDDYLATION PROTEIN1 (Saccharomycescerevisiae) |
PF03556(Cullin_binding) | 4 | LEU A 116GLN A 137THR A 133THR A 109 | None | 1.26A | 2zj0B-3o6bA:undetectable | 2zj0B-3o6bA:16.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3one | ADENOSYLHOMOCYSTEINASE (Lupinus luteus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | LEU A 61GLN A 66THR A 67THR A 206HIS A 350 | NoneADE A 506 (-3.8A)ADE A 506 (-4.5A)NAD A 501 (-2.8A)None | 0.68A | 2zj0B-3oneA:58.1 | 2zj0B-3oneA:59.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q31 | CARBONIC ANHYDRASE (Aspergillusoryzae) |
PF00194(Carb_anhydrase) | 4 | LEU A 234GLN A 237THR A 235THR A 126 | None | 1.32A | 2zj0B-3q31A:undetectable | 2zj0B-3q31A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qr5 | CARDIAC CA2+ RELEASECHANNEL (Mus musculus) |
PF08709(Ins145_P3_rec) | 4 | GLN A 33THR A 27THR A 210HIS A 193 | None | 1.19A | 2zj0B-3qr5A:undetectable | 2zj0B-3qr5A:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tu5 | GELSOLIN,PROTEINCORDON-BLEU,THYMOSINBETA-4 (Homo sapiens;Mus musculus) |
PF00626(Gelsolin) | 4 | LEU B 47GLN B 58THR B 49THR B 81 | None | 1.01A | 2zj0B-3tu5B:undetectable | 2zj0B-3tu5B:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ugm | TAL EFFECTORAVRBS3/PTHA (Xanthomonasoryzae) |
PF03377(TAL_effector) | 4 | LEU A 612GLN A 582THR A 580HIS A 592 | None | 1.03A | 2zj0B-3ugmA:undetectable | 2zj0B-3ugmA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ugm | TAL EFFECTORAVRBS3/PTHA (Xanthomonasoryzae) |
PF03377(TAL_effector) | 4 | LEU A 612GLN A 583THR A 580HIS A 592 | None | 1.14A | 2zj0B-3ugmA:undetectable | 2zj0B-3ugmA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ugm | TAL EFFECTORAVRBS3/PTHA (Xanthomonasoryzae) |
PF03377(TAL_effector) | 4 | LEU A 884GLN A 854THR A 852HIS A 864 | None | 1.17A | 2zj0B-3ugmA:undetectable | 2zj0B-3ugmA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vmn | DEXTRANASE (Streptococcusmutans) |
PF13199(Glyco_hydro_66) | 4 | LEU A 638GLN A 602THR A 603THR A 635 | None | 0.85A | 2zj0B-3vmnA:undetectable | 2zj0B-3vmnA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bkm | PYRIDOXAL PHOSPHATEPHOSPHATASE,PHOSPHOGLYCOLATEPHOSPHATASE,PYRIDOXAL PHOSPHATEPHOSPHATASE (Mus musculus) |
PF13242(Hydrolase_like)PF13344(Hydrolase_6) | 4 | LEU A 249GLN A 277THR A 263HIS A 257 | None | 1.34A | 2zj0B-4bkmA:2.3 | 2zj0B-4bkmA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ci0 | F420-REDUCINGHYDROGENASE, SUBUNITALPHAF420-REDUCINGHYDROGENASE, SUBUNITGAMMA (Methanothermobactermarburgensis) |
PF00037(Fer4)PF00374(NiFeSe_Hases)PF01058(Oxidored_q6) | 4 | LEU A 381THR A 351THR B 86HIS B 53 | None | 1.24A | 2zj0B-4ci0A:undetectable | 2zj0B-4ci0A:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cnk | L-AMINO ACID OXIDASE (Streptococcuscristatus) |
PF03486(HI0933_like) | 4 | GLN A 156THR A 6THR A 348HIS A 389 | None | 1.17A | 2zj0B-4cnkA:2.3 | 2zj0B-4cnkA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4czw | PAB-DEPENDENTPOLY(A)-SPECIFICRIBONUCLEASE SUBUNITPAN2 (Neurosporacrassa) |
PF00929(RNase_T)PF13423(UCH_1) | 4 | LEU A 531THR A 986THR A 528HIS A 525 | NoneNoneNone ZN A3094 (-3.1A) | 1.17A | 2zj0B-4czwA:undetectable | 2zj0B-4czwA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d8u | D-CYSTEINEDESULFHYDRASE (Salmonellaenterica) |
PF00291(PALP) | 4 | LEU A 321GLN A 77THR A 288HIS A 314 | NoneNoneLLP A 51 ( 4.5A)None | 1.19A | 2zj0B-4d8uA:3.2 | 2zj0B-4d8uA:24.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gmf | YERSINIABACTINBIOSYNTHETIC PROTEINYBTU (Yersiniaenterocolitica) |
PF01408(GFO_IDH_MocA) | 4 | LEU A 168GLN A 331THR A 179HIS A 322 | None | 1.03A | 2zj0B-4gmfA:2.9 | 2zj0B-4gmfA:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h63 | MEDIATOR OF RNAPOLYMERASE IITRANSCRIPTIONSUBUNIT 17 (Schizosaccharomycespombe) |
PF10156(Med17) | 4 | LEU Q 347GLN Q 263THR Q 349HIS Q 394 | None | 1.05A | 2zj0B-4h63Q:undetectable | 2zj0B-4h63Q:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4htw | GAG PROTEIN (Simianimmunodeficiencyvirus) |
PF00607(Gag_p24) | 4 | LEU A 14THR A 18THR A 47HIS A 11 | None | 1.20A | 2zj0B-4htwA:undetectable | 2zj0B-4htwA:14.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l1m | E3 UBIQUITIN-PROTEINLIGASE HERC2 (Homo sapiens) |
PF00415(RCC1) | 4 | LEU A 600GLN A 625THR A 621THR A 647 | NoneNoneNoneSO4 A 802 (-3.5A) | 0.99A | 2zj0B-4l1mA:undetectable | 2zj0B-4l1mA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l7v | PROTEIN-L-ISOASPARTATEO-METHYLTRANSFERASE (Vibrio cholerae) |
PF01135(PCMT) | 4 | LEU A 24GLN A 16THR A 14THR A 68 | None | 1.34A | 2zj0B-4l7vA:3.5 | 2zj0B-4l7vA:19.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4lvc | S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE(SAHASE) (Bradyrhizobiumelkanii) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | LEU A 57GLN A 62THR A 63THR A 198HIS A 342 | NoneNH4 A 502 ( 3.1A)ADN A 501 (-4.5A)NAD A 503 ( 2.9A)ADN A 501 ( 3.7A) | 0.31A | 2zj0B-4lvcA:59.3 | 2zj0B-4lvcA:58.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4maa | PUTATIVEBRANCHED-CHAIN AMINOACID ABCTRANSPORTER,PERIPLASMIC AMINOACID-BINDING PROTEIN (Pseudomonasprotegens) |
PF13458(Peripla_BP_6) | 4 | LEU A 292GLN A 297THR A 296THR A 286 | None | 1.32A | 2zj0B-4maaA:5.5 | 2zj0B-4maaA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nq1 | 4-HYDROXY-TETRAHYDRODIPICOLINATESYNTHASE (Legionellapneumophila) |
PF00701(DHDPS) | 4 | GLN A 111THR A 110THR A 81HIS A 120 | NoneNoneMRD A 301 ( 4.2A)MRD A 301 ( 4.8A) | 1.28A | 2zj0B-4nq1A:undetectable | 2zj0B-4nq1A:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pkh | GELSOLIN,TROPOMODULIN-1 CHIMERA (Homo sapiens) |
PF00626(Gelsolin)PF03250(Tropomodulin) | 4 | LEU B 98GLN B 109THR B 100THR B 132 | None | 1.06A | 2zj0B-4pkhB:undetectable | 2zj0B-4pkhB:16.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pki | GELSOLIN,TROPOMODULIN-1 CHIMERA (Homo sapiens) |
PF00626(Gelsolin) | 4 | LEU G 98GLN G 109THR G 100THR G 132 | None | 1.06A | 2zj0B-4pkiG:undetectable | 2zj0B-4pkiG:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ql6 | CARBOXY-TERMINALPROCESSING PROTEASE (Chlamydiatrachomatis) |
PF00595(PDZ)PF03572(Peptidase_S41) | 4 | GLN A 477THR A 478THR A 483HIS A 231 | None | 1.26A | 2zj0B-4ql6A:undetectable | 2zj0B-4ql6A:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qlb | PROBABLE GLYCOGEN[STARCH] SYNTHASE (Caenorhabditiselegans) |
PF05693(Glycogen_syn) | 4 | LEU A 214GLN A 153THR A 218HIS A 271 | None | 1.31A | 2zj0B-4qlbA:2.1 | 2zj0B-4qlbA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ubq | BETA-LACTAMASE (Acinetobacterbaumannii) |
no annotation | 4 | GLN A 213THR A 210THR A 141HIS A 78 | NoneNoneNone ZN A 301 (-3.4A) | 1.25A | 2zj0B-4ubqA:3.2 | 2zj0B-4ubqA:18.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x4j | PUTATIVE OXYGENASE (Amycolatopsisorientalis) |
PF01494(FAD_binding_3) | 4 | LEU A 330GLN A 286THR A 333HIS A 323 | None | 1.11A | 2zj0B-4x4jA:3.1 | 2zj0B-4x4jA:24.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z94 | GELSOLIN,TROPOMODULIN-1,LEIOMODIN-1 CHIMERA (Homo sapiens) |
PF00626(Gelsolin) | 4 | LEU G 47GLN G 58THR G 49THR G 81 | None | 1.02A | 2zj0B-4z94G:undetectable | 2zj0B-4z94G:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z9h | METHYL-ACCEPTINGCHEMOTAXIS PROTEINII (Escherichiacoli) |
PF02203(TarH) | 4 | LEU A 137GLN A 155THR A 154THR A 146 | None | 1.34A | 2zj0B-4z9hA:undetectable | 2zj0B-4z9hA:14.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zjg | ALPHA-2-MACROGLOBULIN (Escherichiacoli) |
PF11974(MG1) | 4 | LEU A 344GLN A 333THR A 332HIS A 341 | NoneNoneNonePGE A 402 (-4.2A) | 1.08A | 2zj0B-4zjgA:undetectable | 2zj0B-4zjgA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zrq | TRANSCOBALAMIN-2 (Homo sapiens) |
PF01122(Cobalamin_bind)PF14478(DUF4430) | 4 | LEU A 260GLN A 266THR A 228HIS A 221 | None | 1.20A | 2zj0B-4zrqA:undetectable | 2zj0B-4zrqA:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c6u | AMINOTRANSFERASE (Mycobacteriumtuberculosis) |
PF12897(Aminotran_MocR) | 4 | LEU A 6GLN A 9THR A 419HIS A 18 | None | 1.34A | 2zj0B-5c6uA:2.7 | 2zj0B-5c6uA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5chc | DMSO REDUCTASEFAMILY TYPE IIENZYME,MOLYBDOPTERINSUBUNIT (Azospira oryzae) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 4 | LEU A 554GLN A 547THR A 486HIS A 162 | None | 1.16A | 2zj0B-5chcA:3.1 | 2zj0B-5chcA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f9p | ANTHRONEOXIDASE-LIKE PROTEIN (Streptomycesambofaciens) |
PF03992(ABM) | 4 | LEU A 162GLN A 63THR A 12HIS A 159 | NoneNoneNoneGOL A 301 (-3.5A) | 1.08A | 2zj0B-5f9pA:undetectable | 2zj0B-5f9pA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gu6 | ENDOPLASMICRETICULUM RESIDENTPROTEIN 44 (Homo sapiens) |
PF00085(Thioredoxin)PF13848(Thioredoxin_6) | 4 | LEU A 235GLN A 257THR A 264HIS A 323 | None | 1.33A | 2zj0B-5gu6A:undetectable | 2zj0B-5gu6A:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ibv | CAPSID POLYPROTEINVP90 (Mamastrovirus 1) |
PF03115(Astro_capsid_N) | 4 | LEU A 112GLN A 406THR A 405THR A 209 | None | 1.10A | 2zj0B-5ibvA:undetectable | 2zj0B-5ibvA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ibv | CAPSID POLYPROTEINVP90 (Mamastrovirus 1) |
PF03115(Astro_capsid_N) | 4 | LEU A 112GLN A 406THR A 405THR A 218 | None | 1.28A | 2zj0B-5ibvA:undetectable | 2zj0B-5ibvA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ixp | EXTRACELLULARSOLUTE-BINDINGPROTEIN FAMILY 1 (Kribbellaflavida) |
PF13416(SBP_bac_8) | 4 | LEU A 318GLN A 342THR A 338THR A 51 | None | 1.21A | 2zj0B-5ixpA:undetectable | 2zj0B-5ixpA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jwr | CIRCADIAN CLOCKPROTEIN KAIA (Thermosynechococcuselongatus) |
PF07688(KaiA) | 4 | LEU E 239GLN E 246THR E 242THR E 199 | None | 1.34A | 2zj0B-5jwrE:undetectable | 2zj0B-5jwrE:14.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ool | 39S RIBOSOMALPROTEIN L38,MITOCHONDRIAL (Homo sapiens) |
PF01161(PBP) | 4 | LEU 6 236GLN 6 275THR 6 238THR 6 300 | None | 1.28A | 2zj0B-5ool6:undetectable | 2zj0B-5ool6:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5osh | VACUOLAR PROTEINSORTING-ASSOCIATEDPROTEIN 29 (Homo sapiens) |
no annotation | 4 | LEU A 9THR A 136THR A 37HIS A 86 | None | 1.24A | 2zj0B-5oshA:undetectable | 2zj0B-5oshA:9.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5veu | CYTOCHROME P450 3A5 (Homo sapiens) |
no annotation | 4 | LEU A 490GLN A 471THR A 470THR A 317 | None | 1.20A | 2zj0B-5veuA:undetectable | 2zj0B-5veuA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wbf | METHYL-ACCEPTINGCHEMOTAXISTRANSDUCER (TLPC) (Helicobacterpylori) |
no annotation | 4 | LEU A 131GLN A 138THR A 136THR A 116 | None | 1.23A | 2zj0B-5wbfA:undetectable | 2zj0B-5wbfA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xjg | VACUOLAR PROTEIN 8 (Saccharomycescerevisiae) |
PF00514(Arm) | 4 | LEU A 259GLN A 270THR A 229HIS A 296 | NoneNoneNonePE5 A 601 (-4.1A) | 1.23A | 2zj0B-5xjgA:undetectable | 2zj0B-5xjgA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zvt | CORE PROTEIN VP6 (Aquareovirus C) |
no annotation | 4 | LEU U 296GLN U 288THR U 291THR U 316 | None | 1.23A | 2zj0B-5zvtU:undetectable | 2zj0B-5zvtU:10.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6aph | ADENOSYLHOMOCYSTEINASE (Elizabethkingiaanophelis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | LEU A 57GLN A 62THR A 63THR A 162HIS A 306 | NoneADN A 501 (-3.8A)ADN A 501 (-4.5A)NAD A 500 ( 2.9A)ADN A 501 ( 3.7A) | 0.36A | 2zj0B-6aphA:56.0 | 2zj0B-6aphA:54.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b20 | GUANINENUCLEOTIDE-BINDINGPROTEING(I)/G(S)/G(T)SUBUNIT BETA-1 (Bos taurus) |
no annotation | 4 | LEU A 51THR A 87THR A 329HIS A 311 | None | 1.24A | 2zj0B-6b20A:undetectable | 2zj0B-6b20A:10.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bnl | NKT VALPHA14 (MOUSE)- 2C12 TCR - HYBRIDMOUSE VARIABLE ANDHUMAN CONSTANTDOMAINS (Homo sapiens) |
no annotation | 4 | LEU C 20GLN C 111THR C 110THR C 80 | None | 0.94A | 2zj0B-6bnlC:undetectable | 2zj0B-6bnlC:13.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c01 | ECTONUCLEOTIDEPYROPHOSPHATASE/PHOSPHODIESTERASE FAMILYMEMBER 3 (Homo sapiens) |
no annotation | 4 | GLN A 466THR A 378THR A 203HIS A 373 | NoneNoneNone ZN A 902 (-3.3A) | 1.11A | 2zj0B-6c01A:undetectable | 2zj0B-6c01A:8.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f2t | - (-) |
no annotation | 4 | GLN A 466THR A 379THR A 204HIS A 374 | NoneNoneNone ZN A1002 (-3.1A) | 1.13A | 2zj0B-6f2tA:undetectable | 2zj0B-6f2tA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f3m | - (-) |
no annotation | 4 | GLN B 65THR B 66THR B 165HIS B 323 | K B 504 ( 3.0A)ADN B 502 (-4.6A)NAD B 501 ( 2.8A) ZN B 505 (-3.2A) | 0.23A | 2zj0B-6f3mB:51.9 | 2zj0B-6f3mB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gbn | - (-) |
no annotation | 5 | LEU A 55GLN A 60THR A 61THR A 160HIS A 304 | None NA A 503 ( 3.2A)ADN A 501 (-4.6A)NAD A 502 ( 2.8A)ADN A 501 ( 3.6A) | 0.32A | 2zj0B-6gbnA:55.5 | 2zj0B-6gbnA:undetectable |