SIMILAR PATTERNS OF AMINO ACIDS FOR 2ZGW_B_ADNB1302

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ad3 ALDEHYDE
DEHYDROGENASE (CLASS
3)

(Rattus
norvegicus) 		PF00171
(Aldedh) 		4 TRP A  80
GLU A 419
ALA A 129
ALA A 130
 None
 1.02A 2zgwB-1ad3A:
0.0		 2zgwB-1ad3A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1awb MYO-INOSITOL
MONOPHOSPHATASE

(Homo sapiens) 		PF00459
(Inositol_P) 		4 GLU A 260
ALA A 210
ASN A 255
ALA A 253
 None
 1.09A 2zgwB-1awbA:
0.0		 2zgwB-1awbA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c2o ACETYLCHOLINESTERASE

(Electrophorus
electricus) 		PF00135
(COesterase) 		4 TRP A 182
GLU A 185
ALA A 189
ALA A 188
 None
 1.17A 2zgwB-1c2oA:
0.0		 2zgwB-1c2oA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c7t BETA-N-ACETYLHEXOSAM
INIDASE

(Serratia
marcescens) 		PF00728
(Glyco_hydro_20)
PF02838
(Glyco_hydro_20b)
PF03173
(CHB_HEX)
PF03174
(CHB_HEX_C) 		4 GLU A 883
ALA A 833
PRO A 195
ALA A 824
 None
 1.20A 2zgwB-1c7tA:
undetectable		 2zgwB-1c7tA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ge7 PEPTIDYL-LYS
METALLOENDOPEPTIDASE

(Grifola
frondosa) 		PF14521
(Aspzincin_M35) 		4 GLU A 157
ALA A 137
ASN A 152
ALA A 138
 None
 1.15A 2zgwB-1ge7A:
0.0		 2zgwB-1ge7A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gll GLYCEROL KINASE

(Escherichia
coli) 		no annotation 4 GLU Y 277
ALA Y 301
ASN Y 274
ALA Y 291
 None
 1.17A 2zgwB-1gllY:
0.3		 2zgwB-1gllY:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gy9 ALPHA-KETOGLUTARATE-
DEPENDENT TAURINE
DIOXYGENASE

(Escherichia
coli) 		PF02668
(TauD) 		4 GLU A 118
ALA A 115
ASN A 243
ALA A 116
 None
 1.14A 2zgwB-1gy9A:
undetectable		 2zgwB-1gy9A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ih5 AQUAPORIN-1

(Homo sapiens) 		PF00230
(MIP) 		4 ALA A 105
ASN A  76
PRO A 193
ALA A 194
 None
 1.16A 2zgwB-1ih5A:
0.1		 2zgwB-1ih5A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR

(Homo sapiens) 		PF00079
(Serpin) 		4 GLU A 104
ALA A 385
ASN A  32
ALA A  35
 None
 1.08A 2zgwB-1imvA:
0.0		 2zgwB-1imvA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jif BLEOMYCIN-BINDING
PROTEIN

(Streptomyces
verticillus) 		no annotation 4 ALA A  13
ASN A 114
PRO A 111
ALA A 112
 None
 1.18A 2zgwB-1jifA:
undetectable		 2zgwB-1jifA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jnf SEROTRANSFERRIN

(Oryctolagus
cuniculus) 		PF00405
(Transferrin) 		4 ALA A 583
ASN A 581
PRO A 421
ALA A 409
 None
 1.11A 2zgwB-1jnfA:
undetectable		 2zgwB-1jnfA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jtd BETA-LACTAMASE
INHIBITOR PROTEIN II

(Streptomyces
exfoliatus) 		PF13540
(RCC1_2) 		4 TRP B  87
GLU B  55
ALA B  70
ALA B 110
 None
 1.18A 2zgwB-1jtdB:
undetectable		 2zgwB-1jtdB:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1krm ADENOSINE DEAMINASE

(Bos taurus) 		PF00962
(A_deaminase) 		4 GLU A  10
ALA A 327
ASN A 323
ALA A 326
 None
 0.95A 2zgwB-1krmA:
undetectable		 2zgwB-1krmA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kz1 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE

(Schizosaccharomyces
pombe) 		PF00885
(DMRL_synthase) 		4 GLU A  33
ALA A 130
PRO A  34
ALA A 134
 None
 1.12A 2zgwB-1kz1A:
undetectable		 2zgwB-1kz1A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mky PROBABLE GTP-BINDING
PROTEIN ENGA

(Thermotoga
maritima) 		PF01926
(MMR_HSR1)
PF14714
(KH_dom-like) 		4 GLU A 141
ALA A 120
PRO A 142
ALA A 117
 None
 1.10A 2zgwB-1mkyA:
undetectable		 2zgwB-1mkyA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ogp SULFITE OXIDASE

(Arabidopsis
thaliana) 		PF00174
(Oxidored_molyb)
PF03404
(Mo-co_dimer) 		4 GLU A 319
ALA A  94
ASN A 124
ALA A 335
 None
 1.15A 2zgwB-1ogpA:
0.3		 2zgwB-1ogpA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q8r CROSSOVER JUNCTION
ENDODEOXYRIBONUCLEAS
E RUSA

(Escherichia
coli) 		PF05866
(RusA) 		4 GLU A  30
ALA A  81
PRO A  12
ALA A  77
 None
 1.18A 2zgwB-1q8rA:
undetectable		 2zgwB-1q8rA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1suv SEROTRANSFERRIN,
C-LOBE

(Homo sapiens) 		PF00405
(Transferrin) 		4 ALA E 583
ASN E 581
PRO E 421
ALA E 409
 None
 1.11A 2zgwB-1suvE:
undetectable		 2zgwB-1suvE:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2x ADP-SPECIFIC
PHOSPHOFRUCTOKINASE

(Pyrococcus
horikoshii) 		PF04587
(ADP_PFK_GK) 		4 GLU A 282
ALA A  33
ASN A  35
ALA A 120
 None
None
SO4  A1003 (-3.8A)
None
 1.07A 2zgwB-1u2xA:
4.7		 2zgwB-1u2xA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uio ADENOSINE DEAMINASE

(Mus musculus) 		PF00962
(A_deaminase) 		4 GLU A  13
ALA A 330
ASN A 326
ALA A 329
 None
 1.00A 2zgwB-1uioA:
undetectable		 2zgwB-1uioA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vzh DESULFOFERRODOXIN

(Desulfarculus
baarsii) 		PF01880
(Desulfoferrodox)
PF06397
(Desulfoferrod_N) 		4 GLU A 114
ASN A  40
PRO A  51
ALA A 124
 None
 1.11A 2zgwB-1vzhA:
undetectable		 2zgwB-1vzhA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wkm METHIONINE
AMINOPEPTIDASE

(Pyrococcus
furiosus) 		PF00557
(Peptidase_M24) 		4 GLU A 136
ALA A 111
PRO A 146
ALA A 190
 None
 1.12A 2zgwB-1wkmA:
undetectable		 2zgwB-1wkmA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wr8 PHOSPHOGLYCOLATE
PHOSPHATASE

(Pyrococcus
horikoshii) 		PF08282
(Hydrolase_3) 		4 GLU A 179
ALA A 193
PRO A 198
ALA A 197
 None
 1.17A 2zgwB-1wr8A:
undetectable		 2zgwB-1wr8A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z66 MAJOR ENVELOPE
PROTEIN E

(Langat virus) 		PF02832
(Flavi_glycop_C) 		4 GLU A 351
ALA A 355
ASN A 381
ALA A 344
 None
 1.14A 2zgwB-1z66A:
undetectable		 2zgwB-1z66A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zo1 TRANSLATION
INITIATION FACTOR 2

(Escherichia
coli) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF11987
(IF-2) 		4 GLU I 524
ALA I 574
ASN I 576
ALA I 573
 None
 1.14A 2zgwB-1zo1I:
undetectable		 2zgwB-1zo1I:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE

(Sarocladium
strictum) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 GLU A 461
ALA A 474
PRO A 460
ALA A 456
 None
 1.10A 2zgwB-1zr6A:
1.2		 2zgwB-1zr6A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zrt CYTOCHROME C1

(Rhodobacter
capsulatus) 		PF02167
(Cytochrom_C1) 		4 GLU D 129
ALA D 217
PRO D 128
ALA D 104
 None
 1.12A 2zgwB-1zrtD:
undetectable		 2zgwB-1zrtD:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV

(Escherichia
coli) 		PF01026
(TatD_DNase) 		4 GLU A  97
ALA A  94
PRO A  39
ALA A  62
 ZN  A 401 ( 2.3A)
None
None
None
 1.13A 2zgwB-1zzmA:
undetectable		 2zgwB-1zzmA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a2f EXOCYST COMPLEX
COMPONENT SEC15

(Drosophila
melanogaster) 		PF04091
(Sec15) 		4 GLU X 167
ALA X 107
ASN X 103
ALA X 106
 None
 1.20A 2zgwB-2a2fX:
undetectable		 2zgwB-2a2fX:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c3z INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE

(Sulfolobus
solfataricus) 		PF00218
(IGPS) 		4 GLU A  39
ALA A 229
ASN A  41
ALA A  47
 None
 1.10A 2zgwB-2c3zA:
undetectable		 2zgwB-2c3zA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cuy MALONYL COA-[ACYL
CARRIER PROTEIN]
TRANSACYLASE

(Thermus
thermophilus) 		PF00698
(Acyl_transf_1) 		4 GLU A 231
ALA A  95
PRO A 217
ALA A  99
 None
 1.14A 2zgwB-2cuyA:
undetectable		 2zgwB-2cuyA:
24.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2djz 235AA LONG
HYPOTHETICAL
BIOTIN-[ACETYL-COA-C
ARBOXYLASE] LIGASE

(Pyrococcus
horikoshii) 		PF02237
(BPL_C)
PF03099
(BPL_LplA_LipB) 		6 TRP A  53
GLU A  54
ALA A 111
ASN A 131
PRO A 137
ALA A 140
 BT5  A1301 (-3.8A)
None
BT5  A1301 ( 3.8A)
BT5  A1301 (-3.0A)
BT5  A1301 (-4.6A)
BT5  A1301 (-3.4A)
 0.17A 2zgwB-2djzA:
41.2		 2zgwB-2djzA:
99.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2du9 PREDICTED
TRANSCRIPTIONAL
REGULATORS

(Corynebacterium
glutamicum) 		PF00392
(GntR) 		4 ALA A  36
ASN A  32
PRO A  42
ALA A  35
 None
 1.08A 2zgwB-2du9A:
undetectable		 2zgwB-2du9A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ecf DIPEPTIDYL PEPTIDASE
IV

(Stenotrophomonas
maltophilia) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		4 TRP A 639
ASN A 611
PRO A 527
ALA A 528
 None
 0.99A 2zgwB-2ecfA:
undetectable		 2zgwB-2ecfA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2htm THIAZOLE
BIOSYNTHESIS PROTEIN
THIG

(Thermus
thermophilus) 		PF05690
(ThiG) 		4 GLU A  30
ALA A  35
PRO A 217
ALA A 220
 None
 1.09A 2zgwB-2htmA:
undetectable		 2zgwB-2htmA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kp6 UNCHARACTERIZED
PROTEIN

(Chromobacterium
violaceum) 		PF10982
(DUF2789) 		4 GLU A  41
ALA A  67
PRO A  38
ALA A  71
 None
 1.17A 2zgwB-2kp6A:
undetectable		 2zgwB-2kp6A:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kr1 UBIQUITIN PROTEIN
LIGASE E3A

(Homo sapiens) 		PF16558
(AZUL) 		4 GLU A  19
ALA A  46
ASN A  42
ALA A  45
 None
 1.14A 2zgwB-2kr1A:
undetectable		 2zgwB-2kr1A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l4o CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
pneumoniae) 		PF16555
(GramPos_pilinD1) 		4 GLU A  55
ALA A  44
PRO A  70
ALA A  73
 None
 0.80A 2zgwB-2l4oA:
undetectable		 2zgwB-2l4oA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ox4 PUTATIVE MANDELATE
RACEMASE

(Zymomonas
mobilis) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 GLU A 330
ALA A 305
ASN A 335
ALA A 302
 None
 1.18A 2zgwB-2ox4A:
undetectable		 2zgwB-2ox4A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p10 MLL9387 PROTEIN

(Mesorhizobium
japonicum) 		PF09370
(PEP_hydrolase) 		4 GLU A 215
ALA A 220
PRO A 172
ALA A 175
 ACT  A 288 (-4.4A)
None
ACT  A 287 (-4.8A)
None
 1.12A 2zgwB-2p10A:
undetectable		 2zgwB-2p10A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r1v DJ-1

(Homo sapiens) 		PF01965
(DJ-1_PfpI) 		4 GLU A  15
ALA A 129
ASN A  76
ALA A 107
 None
 0.96A 2zgwB-2r1vA:
undetectable		 2zgwB-2r1vA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wp1 BROMODOMAIN
TESTIS-SPECIFIC
PROTEIN

(Mus musculus) 		PF00439
(Bromodomain) 		4 GLU A 378
ALA A 337
PRO A 379
ALA A 333
 None
 1.20A 2zgwB-2wp1A:
undetectable		 2zgwB-2wp1A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yzm D-ALANINE--D-ALANINE
LIGASE

(Thermus
thermophilus) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 GLU A  60
ALA A  55
PRO A  59
ALA A  57
 None
 1.15A 2zgwB-2yzmA:
undetectable		 2zgwB-2yzmA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zcw TRANSCRIPTIONAL
REGULATOR, FNR/CRP
FAMILY

(Thermus
thermophilus) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		4 GLU A 192
ALA A 124
ASN A 120
ALA A 123
 None
 1.20A 2zgwB-2zcwA:
undetectable		 2zgwB-2zcwA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zhp BLEOMYCIN RESISTANCE
PROTEIN

(Streptoalloteichus
hindustanus) 		no annotation 4 ALA A  13
ASN A 114
PRO A 111
ALA A 112
 None
 1.19A 2zgwB-2zhpA:
undetectable		 2zgwB-2zhpA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zxo SINGLE-STRANDED DNA
SPECIFIC EXONUCLEASE
RECJ

(Thermus
thermophilus) 		PF01368
(DHH)
PF02272
(DHHA1) 		4 GLU A 459
ALA A  31
PRO A 460
ALA A  34
 None
 1.17A 2zgwB-2zxoA:
5.0		 2zgwB-2zxoA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bf8 ESTERASE YBFF

(Escherichia
coli) 		PF12697
(Abhydrolase_6) 		5 TRP A 188
GLU A 189
ALA A  94
PRO A  65
ALA A  68
 None
 1.26A 2zgwB-3bf8A:
undetectable		 2zgwB-3bf8A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cne PUTATIVE PROTEASE I

(Bacteroides
thetaiotaomicron) 		PF01965
(DJ-1_PfpI) 		4 GLU A  42
ALA A   9
ASN A  11
ALA A  36
 None
 0.91A 2zgwB-3cneA:
undetectable		 2zgwB-3cneA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3epc PROTEIN VP2

(Enterovirus C) 		PF00073
(Rhv) 		4 GLU 2  55
ALA 2  59
ASN 2  95
ALA 2  60
 None
 1.09A 2zgwB-3epc2:
undetectable		 2zgwB-3epc2:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3epf PROTEIN VP2

(Enterovirus C) 		PF00073
(Rhv) 		4 GLU 2  55
ALA 2  59
ASN 2  95
ALA 2  60
 None
 1.00A 2zgwB-3epf2:
undetectable		 2zgwB-3epf2:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g3l PUTATIVE
UNCHARACTERIZED
MEMBRANE-ASSOCIATED
PROTEIN

(Bacteroides
fragilis) 		PF12985
(DUF3869) 		4 GLU A  60
ALA A  55
ASN A 275
ALA A 122
 None
None
GOL  A  10 (-4.3A)
None
 1.12A 2zgwB-3g3lA:
undetectable		 2zgwB-3g3lA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iz3 VIRAL STRUCTURAL
PROTEIN 5

(Cypovirus 1) 		no annotation 4 GLU D 209
ALA D 125
ASN D 129
ALA D 126
 None
 1.14A 2zgwB-3iz3D:
undetectable		 2zgwB-3iz3D:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jq1 SUSD SUPERFAMILY
PROTEIN

(Bacteroides
vulgatus) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 GLU A 143
ALA A 217
PRO A 209
ALA A 213
 None
 1.06A 2zgwB-3jq1A:
undetectable		 2zgwB-3jq1A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kz1 RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 11

(Homo sapiens) 		PF00621
(RhoGEF) 		4 GLU A 824
ALA A 830
ASN A 781
ALA A 829
 None
 1.14A 2zgwB-3kz1A:
undetectable		 2zgwB-3kz1A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lk6 LIPOPROTEIN YBBD

(Bacillus
subtilis) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C) 		4 ALA A 431
ASN A 595
PRO A 597
ALA A 598
 None
 1.17A 2zgwB-3lk6A:
undetectable		 2zgwB-3lk6A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lk6 LIPOPROTEIN YBBD

(Bacillus
subtilis) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C) 		4 GLU A 427
ALA A 147
PRO A 139
ALA A 143
 None
 1.08A 2zgwB-3lk6A:
undetectable		 2zgwB-3lk6A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nmb PUTATIVE SUGAR
HYDROLASE

(Bacteroides
ovatus) 		PF06439
(DUF1080) 		4 GLU A 223
ALA A 185
PRO A 195
ALA A 193
 None
 1.16A 2zgwB-3nmbA:
undetectable		 2zgwB-3nmbA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwp 6-PHOSPHOGLUCONOLACT
ONASE

(Shewanella
baltica) 		PF01182
(Glucosamine_iso) 		5 TRP A  74
GLU A  72
ALA A 115
ASN A 106
ALA A 118
 None
 1.25A 2zgwB-3nwpA:
undetectable		 2zgwB-3nwpA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ozq SERPIN48

(Tenebrio
molitor) 		PF00079
(Serpin) 		4 GLU A 168
ALA A 145
PRO A 167
ALA A 146
 None
 1.17A 2zgwB-3ozqA:
undetectable		 2zgwB-3ozqA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qka ENOYL-COA HYDRATASE,
ECHA5

(Mycobacterium
marinum) 		PF00378
(ECH_1) 		4 GLU A  73
ASN A  75
PRO A  30
ALA A  32
 None
 1.12A 2zgwB-3qkaA:
undetectable		 2zgwB-3qkaA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r9b CYTOCHROME P450
164A2

(Mycolicibacterium
smegmatis) 		PF00067
(p450) 		4 GLU A 389
ALA A 284
PRO A 388
ALA A 283
 None
 0.88A 2zgwB-3r9bA:
undetectable		 2zgwB-3r9bA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6o POLYSACCHARIDE
DEACETYLASE FAMILY
PROTEIN

(Burkholderia
pseudomallei) 		PF01522
(Polysacc_deac_1) 		4 ALA A  64
ASN A  43
PRO A  50
ALA A  51
 None
 0.87A 2zgwB-3s6oA:
undetectable		 2zgwB-3s6oA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3szb ALDEHYDE
DEHYDROGENASE

(Homo sapiens) 		PF00171
(Aldedh) 		4 TRP A  80
GLU A 419
ALA A 129
ALA A 130
 None
 0.96A 2zgwB-3szbA:
undetectable		 2zgwB-3szbA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vis ESTERASE

(Thermobifida
alba) 		PF12740
(Chlorophyllase2) 		4 ALA A 245
ASN A 254
PRO A 250
ALA A 249
 None
 1.15A 2zgwB-3visA:
undetectable		 2zgwB-3visA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w3a V-TYPE ATP SYNTHASE
ALPHA CHAIN

(Thermus
thermophilus) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N)
PF16886
(ATP-synt_ab_Xtn) 		4 ALA A 301
ASN A 290
PRO A 295
ALA A 298
 None
 1.02A 2zgwB-3w3aA:
undetectable		 2zgwB-3w3aA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyv AOX3

(Mus musculus) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		4 GLU A1168
ALA A1281
ASN A 993
ALA A1282
 None
 1.19A 2zgwB-3zyvA:
undetectable		 2zgwB-3zyvA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a29 ENGINEERED
RETRO-ALDOL ENZYME
RA95.0

(synthetic
construct) 		PF00218
(IGPS) 		4 GLU A  39
ALA A 229
ASN A  41
ALA A  47
 None
 0.92A 2zgwB-4a29A:
undetectable		 2zgwB-4a29A:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cg1 CUTINASE

(Thermobifida
fusca) 		PF12740
(Chlorophyllase2) 		4 ALA A 206
ASN A 215
PRO A 211
ALA A 210
 None
 1.12A 2zgwB-4cg1A:
undetectable		 2zgwB-4cg1A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ci0 F420-REDUCING
HYDROGENASE, SUBUNIT
ALPHA

(Methanothermobacter
marburgensis) 		PF00374
(NiFeSe_Hases) 		4 GLU A 165
ALA A  89
ASN A 162
ALA A 305
 None
 1.20A 2zgwB-4ci0A:
undetectable		 2zgwB-4ci0A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cta CINA-LIKE PROTEIN

(Thermus
thermophilus) 		PF00994
(MoCF_biosynth)
PF02464
(CinA) 		4 GLU A  46
ALA A  81
PRO A  49
ALA A  51
 None
 1.19A 2zgwB-4ctaA:
undetectable		 2zgwB-4ctaA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d1y PUTATIVE PROTEASE I

(Bacteroides
thetaiotaomicron) 		PF01965
(DJ-1_PfpI) 		4 GLU A  42
ALA A   9
ASN A  11
ALA A  36
 None
 0.83A 2zgwB-4d1yA:
undetectable		 2zgwB-4d1yA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eb0 LCC

(uncultured
bacterium) 		PF12695
(Abhydrolase_5) 		4 ALA A 240
ASN A 249
PRO A 245
ALA A 244
 None
 1.18A 2zgwB-4eb0A:
undetectable		 2zgwB-4eb0A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ewt PEPTIDASE,
M20/M25/M40 FAMILY

(Staphylococcus
aureus) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 GLU A 282
ALA A 208
ASN A 206
ALA A 211
 None
None
PEG  A 403 (-3.9A)
None
 1.09A 2zgwB-4ewtA:
3.7		 2zgwB-4ewtA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gs5 ACYL-COA SYNTHETASE
(AMP-FORMING)/AMP-AC
ID LIGASE II-LIKE
PROTEIN

(Dyadobacter
fermentans) 		PF00501
(AMP-binding) 		4 ALA A 189
ASN A 191
PRO A 193
ALA A 195
 None
 1.16A 2zgwB-4gs5A:
undetectable		 2zgwB-4gs5A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iov CAPSID PROTEIN VP1

(Adeno-associated
virus) 		PF00740
(Parvo_coat) 		4 GLU A 560
ALA A 565
ASN A 567
ALA A 564
 None
 1.00A 2zgwB-4iovA:
undetectable		 2zgwB-4iovA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4irl MALTOSE-BINDING
PERIPLASMIC PROTEIN,
NOVEL PROTEIN
SIMILAR TO
VERTEBRATE GUANYLATE
BINDING PROTEIN
FAMILY

(Danio rerio;
Escherichia
coli) 		PF00619
(CARD)
PF13416
(SBP_bac_8) 		4 GLU A 441
ALA A 339
ASN A 368
ALA A 372
 None
 1.10A 2zgwB-4irlA:
undetectable		 2zgwB-4irlA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l4w ESPG3

(Mycolicibacterium
smegmatis) 		PF14011
(ESX-1_EspG) 		4 TRP A 264
GLU A 201
ALA A  99
ALA A  78
 None
 1.16A 2zgwB-4l4wA:
undetectable		 2zgwB-4l4wA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n6d TRAP DICARBOXYLATE
TRANSPORTER-DCTP
SUBUNIT

(Desulfovibrio
salexigens) 		PF03480
(DctP) 		4 GLU A 109
ALA A 120
PRO A 234
ALA A 146
 None
 0.91A 2zgwB-4n6dA:
undetectable		 2zgwB-4n6dA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nzs BETA-KETOTHIOLASE
BKTB

(Cupriavidus
necator) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 ALA A 354
ASN A  56
PRO A  27
ALA A 117
 None
 1.03A 2zgwB-4nzsA:
undetectable		 2zgwB-4nzsA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qfe ENOYL-COA HYDRATASE

(Mycolicibacterium
smegmatis) 		PF00378
(ECH_1) 		4 GLU A  73
ASN A  75
PRO A  30
ALA A  32
 None
 1.16A 2zgwB-4qfeA:
undetectable		 2zgwB-4qfeA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tmd UNCHARACTERIZED
PROTEIN

(Mycolicibacterium
smegmatis) 		no annotation 4 GLU A 163
ALA A 198
ASN A  95
ALA A 180
 None
 1.13A 2zgwB-4tmdA:
undetectable		 2zgwB-4tmdA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4upi SULFATASE FAMILY
PROTEIN

(Ruegeria
pomeroyi) 		PF00884
(Sulfatase) 		4 GLU A 198
ALA A 171
PRO A 240
ALA A 194
 None
 1.14A 2zgwB-4upiA:
undetectable		 2zgwB-4upiA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wfi CUTINASE

(Saccharomonospora
viridis) 		PF03403
(PAF-AH_p_II) 		4 ALA A 252
ASN A 261
PRO A 257
ALA A 256
 None
 1.15A 2zgwB-4wfiA:
undetectable		 2zgwB-4wfiA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aa6 VANADIUM-DEPENDENT
BROMOPEROXIDASE 2

(Ascophyllum
nodosum) 		no annotation 4 TRP A 236
GLU A 546
ALA A 527
ALA A 452
 None
 0.80A 2zgwB-5aa6A:
0.5		 2zgwB-5aa6A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnt ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Pseudomonas
aeruginosa) 		no annotation 4 GLU C 174
ALA C 182
PRO C 214
ALA C 181
 None
 1.17A 2zgwB-5bntC:
undetectable		 2zgwB-5bntC:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cj3 ZBM BINDING PROTEIN

(Streptomyces
flavoviridis) 		no annotation 4 ALA A  13
ASN A 114
PRO A 111
ALA A 112
 None
 1.18A 2zgwB-5cj3A:
undetectable		 2zgwB-5cj3A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5csa ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF00364
(Biotin_lipoyl)
PF08326
(ACC_central) 		4 TRP A 843
ALA A 911
PRO A 877
ALA A 878
 None
 0.99A 2zgwB-5csaA:
undetectable		 2zgwB-5csaA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fsa CYP51 VARIANT1

(Candida
albicans) 		PF00067
(p450) 		4 ALA A 430
ASN A 364
PRO A 360
ALA A 431
 None
 1.16A 2zgwB-5fsaA:
undetectable		 2zgwB-5fsaA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gin C/D BOX METHYLATION
GUIDE
RIBONUCLEOPROTEIN
COMPLEX ANOP56
SUBUNIT

(Sulfolobus
solfataricus) 		PF01798
(Nop) 		4 GLU A 255
ALA A 140
PRO A 271
ALA A 275
 None
 1.16A 2zgwB-5ginA:
undetectable		 2zgwB-5ginA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gjw VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1

(Oryctolagus
cuniculus) 		PF00092
(VWA)
PF08399
(VWA_N)
PF08473
(VGCC_alpha2) 		4 GLU F 414
ASN F 424
PRO F 416
ALA F 420
 None
 1.02A 2zgwB-5gjwF:
undetectable		 2zgwB-5gjwF:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hxd PROTEIN MPAA

(Escherichia
coli) 		PF00246
(Peptidase_M14) 		4 GLU A  18
ALA A  37
PRO A  33
ALA A  34
 None
 1.04A 2zgwB-5hxdA:
undetectable		 2zgwB-5hxdA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jbw 3-HYDROXYBUTYRYL-COA
DEHYDRATASE

(Myxococcus
xanthus) 		PF00378
(ECH_1) 		4 GLU A 183
ALA A 169
PRO A 124
ALA A 168
 None
 1.16A 2zgwB-5jbwA:
undetectable		 2zgwB-5jbwA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5od2 BIFUNCTIONAL
ADP-SPECIFIC
GLUCOKINASE/PHOSPHOF
RUCTOKINASE

(Methanocaldococcus
jannaschii) 		no annotation 4 GLU A 272
ALA A  22
ASN A  24
ALA A 109
 None
 1.06A 2zgwB-5od2A:
3.7		 2zgwB-5od2A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uto EDD DOMAIN PROTEIN,
DEGV FAMILY

(Staphylococcus
aureus) 		no annotation 4 ALA A 268
ASN A 167
PRO A  60
ALA A 269
 None
 1.01A 2zgwB-5utoA:
undetectable		 2zgwB-5utoA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wk1 MAJOR CAPSID PROTEIN

(Pseudoalteromonas
phage TW1) 		no annotation 4 TRP A 255
ALA A 272
ASN A 268
ALA A 271
 None
 1.18A 2zgwB-5wk1A:
undetectable		 2zgwB-5wk1A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wx3 ALKYLDIKETIDE-COA
SYNTHASE

(Tetradium
ruticarpum) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 GLU A 186
ALA A 102
PRO A 334
ALA A 214
 None
 1.16A 2zgwB-5wx3A:
undetectable		 2zgwB-5wx3A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yac TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5B

(Pyrococcus
abyssi) 		PF02475
(Met_10) 		4 GLU A 221
ALA A 191
PRO A 234
ALA A 209
 None
 1.06A 2zgwB-5yacA:
undetectable		 2zgwB-5yacA:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6an5 ABC TRANSPORTER

(Aquifex
aeolicus) 		no annotation 4 GLU A  89
ALA A 151
ASN A 107
ALA A 155
 None
 1.06A 2zgwB-6an5A:
undetectable		 2zgwB-6an5A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c8z ADP-DEPENDENT
PHOSPHOFRUCTOKINASE

(Methanosarcinales) 		no annotation 4 GLU A 282
ALA A  30
ASN A  32
ALA A 117
 None
 1.17A 2zgwB-6c8zA:
4.7		 2zgwB-6c8zA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cp2 -

(-) 		no annotation 4 GLU B 118
ALA B 123
PRO B 117
ALA B 126
 None
 1.19A 2zgwB-6cp2B:
undetectable		 2zgwB-6cp2B:
undetectable