SIMILAR PATTERNS OF AMINO ACIDS FOR 2ZBV_A_ADNA501

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mty METHANE
MONOOXYGENASE
HYDROXYLASE

(Methylococcus
capsulatus) 		PF02332
(Phenol_Hydrox) 		5 TYR D 156
VAL D 154
ASN D 100
PHE D 158
ASN D 161
 None
 1.26A 2zbvA-1mtyD:
0.0
2zbvB-1mtyD:
0.0		 2zbvA-1mtyD:
19.00
2zbvB-1mtyD:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wso F-BOX ONLY PROTEIN
44

(Homo sapiens) 		PF04300
(FBA)
PF12937
(F-box-like) 		5 ASP A 162
TRP A 163
VAL A 122
ASN A  80
ASN A  84
 None
 1.38A 2zbvA-3wsoA:
0.0
2zbvB-3wsoA:
0.0		 2zbvA-3wsoA:
20.00
2zbvB-3wsoA:
20.00