SIMILAR PATTERNS OF AMINO ACIDS FOR 2Z97_A_CAMA422

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ayo ALPHA-2-MACROGLOBULI
N

(Bos taurus) 		PF07677
(A2M_recep) 		4 LEU A  98
VAL A  97
VAL A  74
VAL A  79
 None
 0.98A 2z97A-1ayoA:
undetectable		 2z97A-1ayoA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c30 CARBAMOYL PHOSPHATE
SYNTHETASE: LARGE
SUBUNIT

(Escherichia
coli) 		PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		4 LEU A 623
VAL A 626
VAL A 661
VAL A 638
 None
 0.79A 2z97A-1c30A:
0.0		 2z97A-1c30A:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c3c PROTEIN
(ADENYLOSUCCINATE
LYASE)

(Thermotoga
maritima) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		4 LEU A 124
VAL A 127
VAL A 251
VAL A 336
 None
 0.88A 2z97A-1c3cA:
0.0		 2z97A-1c3cA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c8o ICE INHIBITOR

(Cowpox virus) 		PF00079
(Serpin) 		4 THR A  38
VAL A 275
VAL A 251
VAL A 247
 None
 0.98A 2z97A-1c8oA:
undetectable		 2z97A-1c8oA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d5c RAB6 GTPASE

(Plasmodium
falciparum) 		PF00071
(Ras) 		4 THR A 168
LEU A  14
VAL A 122
VAL A  90
 None
 0.98A 2z97A-1d5cA:
undetectable		 2z97A-1d5cA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT

(Rhodobacter
capsulatus) 		PF01078
(Mg_chelatase) 		4 LEU A  65
VAL A  62
VAL A 213
VAL A  50
 None
 0.88A 2z97A-1g8pA:
0.0		 2z97A-1g8pA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT

(Rhodobacter
capsulatus) 		PF01078
(Mg_chelatase) 		4 THR A  39
VAL A  62
VAL A 213
VAL A  50
 None
 0.95A 2z97A-1g8pA:
0.0		 2z97A-1g8pA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jqk CARBON MONOXIDE
DEHYDROGENASE

(Rhodospirillum
rubrum) 		PF03063
(Prismane) 		4 LEU A  84
VAL A 591
VAL A 585
VAL A 615
 None
 0.84A 2z97A-1jqkA:
0.0		 2z97A-1jqkA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kwg BETA-GALACTOSIDASE

(Thermus
thermophilus) 		PF02449
(Glyco_hydro_42)
PF08532
(Glyco_hydro_42M)
PF08533
(Glyco_hydro_42C) 		4 THR A 247
LEU A 424
VAL A 427
VAL A 443
 None
MPD  A 802 ( 4.4A)
None
None
 0.89A 2z97A-1kwgA:
0.0		 2z97A-1kwgA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n2o PANTOTHENATE
SYNTHETASE

(Mycobacterium
tuberculosis) 		PF02569
(Pantoate_ligase) 		4 LEU A 140
VAL A 143
VAL A 181
VAL A 155
 None
 0.80A 2z97A-1n2oA:
undetectable		 2z97A-1n2oA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r8o KUNITZ TRYPSIN
INHIBITOR
KUNITZ TRYPSIN
INHIBITOR

(Copaifera
langsdorffii;
Copaifera
langsdorffii) 		PF00197
(Kunitz_legume)
PF00197
(Kunitz_legume) 		4 LEU B 151
VAL A  44
VAL A  57
VAL A  78
 None
 0.91A 2z97A-1r8oB:
undetectable		 2z97A-1r8oB:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rfv PYRIDOXAL KINASE

(Ovis aries) 		PF08543
(Phos_pyr_kin) 		4 LEU A 132
VAL A 135
VAL A  94
VAL A  95
 None
 0.99A 2z97A-1rfvA:
undetectable		 2z97A-1rfvA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v43 SUGAR-BINDING
TRANSPORT
ATP-BINDING PROTEIN

(Pyrococcus
horikoshii) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		4 LEU A 335
VAL A 336
VAL A 352
VAL A 354
 None
 0.98A 2z97A-1v43A:
undetectable		 2z97A-1v43A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5c CHITOSANASE

(Bacillus sp.
(in: Bacteria)) 		PF01270
(Glyco_hydro_8) 		4 THR A 421
LEU A 325
VAL A 328
VAL A  64
 None
 0.82A 2z97A-1v5cA:
undetectable		 2z97A-1v5cA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v6h DIVALENT CATION
TOLERANCE PROTEIN
CUTA1

(Thermus
thermophilus) 		PF03091
(CutA1) 		4 LEU A  74
VAL A  71
VAL A  31
VAL A  57
 None
 0.98A 2z97A-1v6hA:
undetectable		 2z97A-1v6hA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9j BOLA-LIKE PROTEIN
RIKEN CDNA
1110025L05

(Mus musculus) 		PF01722
(BolA) 		4 LEU A  87
VAL A  83
VAL A  48
VAL A  66
 None
 0.66A 2z97A-1v9jA:
undetectable		 2z97A-1v9jA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vav ALGINATE LYASE
PA1167

(Pseudomonas
aeruginosa) 		PF08787
(Alginate_lyase2) 		4 LEU A 169
VAL A 164
VAL A 134
VAL A 117
 None
 0.93A 2z97A-1vavA:
undetectable		 2z97A-1vavA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI

(Escherichia
coli) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		4 TYR A 206
THR A 130
VAL A 228
VAL A 210
 None
 0.99A 2z97A-1we5A:
undetectable		 2z97A-1we5A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xdi RV3303C-LPDA

(Mycobacterium
tuberculosis) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LEU A 257
VAL A 249
VAL A 211
VAL A 188
 None
 0.84A 2z97A-1xdiA:
undetectable		 2z97A-1xdiA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yx2 AMINOMETHYLTRANSFERA
SE

(Bacillus
subtilis) 		PF01571
(GCV_T)
PF08669
(GCV_T_C) 		4 THR A 187
LEU A  99
VAL A 111
VAL A  49
 None
 0.99A 2z97A-1yx2A:
undetectable		 2z97A-1yx2A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yyr TRICHODIENE SYNTHASE

(Fusarium
sporotrichioides) 		PF06330
(TRI5) 		4 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.92A 2z97A-1yyrA:
undetectable		 2z97A-1yyrA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN

(Alicyclobacillus
acidocaldarius) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		4 LEU A 168
VAL A  89
VAL A  72
VAL A  79
 None
 0.85A 2z97A-1z47A:
undetectable		 2z97A-1z47A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aco OUTER MEMBRANE
LIPOPROTEIN BLC

(Escherichia
coli) 		PF08212
(Lipocalin_2) 		4 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 0.91A 2z97A-2acoA:
undetectable		 2z97A-2acoA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cqz 177AA LONG
HYPOTHETICAL PROTEIN

(Pyrococcus
horikoshii) 		PF13023
(HD_3) 		4 LEU A  11
VAL A   8
VAL A  94
VAL A  98
 None
 0.90A 2z97A-2cqzA:
undetectable		 2z97A-2cqzA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cx4 BACTERIOFERRITIN
COMIGRATORY PROTEIN

(Aeropyrum
pernix) 		PF00578
(AhpC-TSA) 		4 THR A  55
VAL A 151
VAL A  70
VAL A  37
 None
 0.97A 2z97A-2cx4A:
undetectable		 2z97A-2cx4A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dv6 NITRITE REDUCTASE

(Hyphomicrobium
denitrificans) 		PF07732
(Cu-oxidase_3) 		4 LEU A 131
VAL A 130
VAL A  27
VAL A  65
 None
 0.98A 2z97A-2dv6A:
undetectable		 2z97A-2dv6A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2enx MANGANESE-DEPENDENT
INORGANIC
PYROPHOSPHATASE

(Streptococcus
agalactiae) 		PF01368
(DHH)
PF02833
(DHHA2) 		4 THR A 107
LEU A 111
VAL A  96
VAL A 102
 None
 0.92A 2z97A-2enxA:
undetectable		 2z97A-2enxA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2exr CYTOKININ
DEHYDROGENASE 7

(Arabidopsis
thaliana) 		PF01565
(FAD_binding_4)
PF09265
(Cytokin-bind) 		4 LEU A 442
VAL A 408
VAL A 312
VAL A 280
 None
 0.92A 2z97A-2exrA:
undetectable		 2z97A-2exrA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hls PROTEIN DISULFIDE
OXIDOREDUCTASE

(Aeropyrum
pernix) 		PF13192
(Thioredoxin_3) 		4 THR A 129
LEU A 218
VAL A 221
VAL A 174
 None
 0.98A 2z97A-2hlsA:
undetectable		 2z97A-2hlsA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hsz NOVEL PREDICTED
PHOSPHATASE

(Histophilus
somni) 		PF13419
(HAD_2) 		4 THR A 103
LEU A 220
VAL A 174
VAL A 192
 None
 0.98A 2z97A-2hszA:
undetectable		 2z97A-2hszA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i0z NAD(FAD)-UTILIZING
DEHYDROGENASES

(Bacillus cereus) 		PF03486
(HI0933_like) 		4 TYR A 138
LEU A 383
VAL A 159
VAL A 133
 None
None
None
FAD  A 501 (-3.9A)
 0.89A 2z97A-2i0zA:
undetectable		 2z97A-2i0zA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jeo URIDINE-CYTIDINE
KINASE 1

(Homo sapiens) 		PF00485
(PRK) 		4 LEU A  25
VAL A 135
VAL A 110
VAL A 129
 None
 0.94A 2z97A-2jeoA:
undetectable		 2z97A-2jeoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kn4 IMMUNOGLOBULIN
G-BINDING PROTEIN G,
SPLICING FACTOR
ARGININE/SERINE-RIC
H 2

(Streptococcus
sp. 'group G';
Homo sapiens) 		PF00076
(RRM_1)
PF01378
(IgG_binding_B) 		4 THR A  82
LEU A  78
VAL A  75
VAL A  90
 None
 0.99A 2z97A-2kn4A:
undetectable		 2z97A-2kn4A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2knb E3 UBIQUITIN-PROTEIN
LIGASE PARKIN

(Rattus
norvegicus) 		PF00240
(ubiquitin) 		4 THR A  21
VAL A  29
VAL A  67
VAL A   5
 None
 0.91A 2z97A-2knbA:
undetectable		 2z97A-2knbA:
11.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		4 TYR A  96
LEU A 244
VAL A 247
VAL A 396
 CAM  A 502 (-4.5A)
HEM  A 501 (-4.5A)
None
None
 1.00A 2z97A-2m56A:
68.9		 2z97A-2m56A:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		6 TYR A  96
THR A 101
LEU A 244
VAL A 247
VAL A 295
VAL A 396
 CAM  A 502 (-4.5A)
HEM  A 501 (-2.9A)
HEM  A 501 (-4.5A)
None
HEM  A 501 (-4.6A)
None
 0.49A 2z97A-2m56A:
68.9		 2z97A-2m56A:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		4 TYR A  96
THR A 101
LEU A 244
VAL A 295
 CAM  A 502 (-4.5A)
HEM  A 501 (-2.9A)
HEM  A 501 (-4.5A)
HEM  A 501 (-4.6A)
 0.86A 2z97A-2m56A:
68.9		 2z97A-2m56A:
99.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m83 PROTEIN PHOSPHATASE
1 REGULATORY SUBUNIT
3A

(Oryctolagus
cuniculus) 		PF03370
(CBM_21) 		4 THR A 135
LEU A 231
VAL A 207
VAL A 161
 None
 0.90A 2z97A-2m83A:
undetectable		 2z97A-2m83A:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ocx NODULATION
FUCOSYLTRANSFERASE
NODZ

(Bradyrhizobium
sp. WM9) 		PF05830
(NodZ) 		4 LEU A 198
VAL A 201
VAL A 239
VAL A 219
 None
 0.94A 2z97A-2ocxA:
undetectable		 2z97A-2ocxA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q2v BETA-D-HYDROXYBUTYRA
TE DEHYDROGENASE

(Pseudomonas
putida) 		PF00106
(adh_short) 		4 LEU A 112
VAL A 115
VAL A 165
VAL A 166
 None
 0.80A 2z97A-2q2vA:
undetectable		 2z97A-2q2vA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus) 		PF04013
(Methyltrn_RNA_2) 		4 LEU A 149
VAL A 101
VAL A 254
VAL A 255
 None
 1.00A 2z97A-2qmmA:
undetectable		 2z97A-2qmmA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qzp ACYLAMINO-ACID-RELEA
SING ENZYME

(Aeropyrum
pernix) 		PF00326
(Peptidase_S9) 		4 TYR A 444
LEU A 568
VAL A 392
VAL A 363
 None
 0.93A 2z97A-2qzpA:
undetectable		 2z97A-2qzpA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rrb CDNA FLJ40872 FIS,
CLONE TUTER2000283,
HIGHLY SIMILAR TO
HOMO SAPIENS
TRANSFORMER-2-BETA
(SFRS10) GENE

(Homo sapiens) 		PF00076
(RRM_1) 		4 THR A 129
LEU A 184
VAL A 147
VAL A 164
 None
 0.74A 2z97A-2rrbA:
undetectable		 2z97A-2rrbA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yz2 PUTATIVE ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0222

(Thermotoga
maritima) 		PF00005
(ABC_tran) 		4 LEU A  23
VAL A  26
VAL A  38
VAL A 209
 None
 0.79A 2z97A-2yz2A:
undetectable		 2z97A-2yz2A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aiz DNA POLYMERASE
SLIDING CLAMP B

(Sulfurisphaera
tokodaii) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 LEU A 205
VAL A 208
VAL A 218
VAL A 232
 None
 0.79A 2z97A-3aizA:
undetectable		 2z97A-3aizA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus) 		PF03069
(FmdA_AmdA) 		4 TYR A 227
LEU A 279
VAL A 278
VAL A 223
 None
 0.83A 2z97A-3b9tA:
undetectable		 2z97A-3b9tA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3a BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF01301
(Glyco_hydro_35) 		4 LEU A 433
VAL A 431
VAL A 498
VAL A 487
 None
 0.99A 2z97A-3d3aA:
undetectable		 2z97A-3d3aA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3emy TRICHODERMA REESEI
ASPARTIC PROTEASE

(Trichoderma
reesei) 		PF00026
(Asp) 		4 LEU A 123
VAL A 121
VAL A  96
VAL A  89
 None
 0.99A 2z97A-3emyA:
undetectable		 2z97A-3emyA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f2b DNA-DIRECTED DNA
POLYMERASE III ALPHA
CHAIN

(Geobacillus
kaustophilus) 		PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		4 THR A1170
LEU A1206
VAL A1209
VAL A1190
 None
 0.84A 2z97A-3f2bA:
undetectable		 2z97A-3f2bA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhx PYRIDOXAL KINASE

(Homo sapiens) 		PF08543
(Phos_pyr_kin) 		4 LEU A 132
VAL A 135
VAL A  94
VAL A  95
 None
 0.99A 2z97A-3fhxA:
undetectable		 2z97A-3fhxA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hno PYROPHOSPHATE-DEPEND
ENT
PHOSPHOFRUCTOKINASE

(Nitrosospira
multiformis) 		PF00365
(PFK) 		4 LEU A 286
VAL A 282
VAL A 214
VAL A 243
 None
 0.69A 2z97A-3hnoA:
undetectable		 2z97A-3hnoA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hnr PROBABLE
METHYLTRANSFERASE
BT9727_4108

(Bacillus
thuringiensis) 		PF08241
(Methyltransf_11) 		4 LEU A  38
VAL A  41
VAL A  70
VAL A  49
 None
 0.91A 2z97A-3hnrA:
undetectable		 2z97A-3hnrA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvu HYPOXANTHINE
PHOSPHORIBOSYLTRANSF
ERASE

(Bacillus
anthracis) 		PF00156
(Pribosyltran) 		4 TYR A 156
VAL A  20
VAL A  98
VAL A 126
 None
 0.96A 2z97A-3hvuA:
undetectable		 2z97A-3hvuA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ib6 UNCHARACTERIZED
PROTEIN

(Listeria
monocytogenes) 		PF13419
(HAD_2) 		4 THR A  12
LEU A 140
VAL A   5
VAL A 117
 None
 0.68A 2z97A-3ib6A:
undetectable		 2z97A-3ib6A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j3i CAPSID PROTEIN

(Penicillium
chrysogenum
virus) 		no annotation 4 THR A 203
LEU A 349
VAL A 280
VAL A 134
 None
 0.96A 2z97A-3j3iA:
undetectable		 2z97A-3j3iA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2q PYROPHOSPHATE-DEPEND
ENT
PHOSPHOFRUCTOKINASE

(Marinobacter
hydrocarbonoclasticus) 		PF00365
(PFK) 		4 LEU A 286
VAL A 282
VAL A 214
VAL A 243
 None
 0.97A 2z97A-3k2qA:
undetectable		 2z97A-3k2qA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lby PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1697C

(Streptococcus
mutans) 		PF06962
(rRNA_methylase) 		4 THR A 111
LEU A  94
VAL A 132
VAL A 150
 None
 0.84A 2z97A-3lbyA:
undetectable		 2z97A-3lbyA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mbt OUTER MEMBRANE
LIPOPROTEIN BLC

(Escherichia
coli) 		PF08212
(Lipocalin_2) 		4 TYR A  21
LEU A 123
VAL A 112
VAL A  88
 None
 0.94A 2z97A-3mbtA:
undetectable		 2z97A-3mbtA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mh9 LIPOPROTEIN LPRG

(Mycobacterium
tuberculosis) 		no annotation 4 THR C  52
LEU C 204
VAL C 194
VAL C 172
 None
 0.93A 2z97A-3mh9C:
undetectable		 2z97A-3mh9C:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1

(Bifidobacterium
longum) 		PF01547
(SBP_bac_1) 		4 LEU A 417
VAL A 422
VAL A  43
VAL A  97
 None
 0.96A 2z97A-3ombA:
undetectable		 2z97A-3ombA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3orf DIHYDROPTERIDINE
REDUCTASE

(Dictyostelium
discoideum) 		PF00106
(adh_short) 		4 LEU A 193
VAL A 196
VAL A   7
VAL A  72
 None
 0.98A 2z97A-3orfA:
undetectable		 2z97A-3orfA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oxn PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Vibrio
parahaemolyticus) 		PF03466
(LysR_substrate) 		4 TYR A 291
THR A 123
VAL A 224
VAL A 190
 None
 0.83A 2z97A-3oxnA:
undetectable		 2z97A-3oxnA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3skv SSFX3

(Streptomyces
sp. SF2575) 		PF13472
(Lipase_GDSL_2) 		4 THR A  71
LEU A 152
VAL A 150
VAL A 103
 None
 0.99A 2z97A-3skvA:
undetectable		 2z97A-3skvA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN

(Coprinopsis
cinerea) 		no annotation 4 TYR A 179
LEU A 144
VAL A 202
VAL A 203
 None
 1.00A 2z97A-3w9aA:
undetectable		 2z97A-3w9aA:
21.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c9m CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		5 TYR A  98
THR A 103
LEU A 252
VAL A 303
VAL A 404
 None
GOL  A1419 (-3.8A)
HEM  A1418 (-4.0A)
GOL  A1419 (-3.9A)
GOL  A1419 (-3.5A)
 0.25A 2z97A-4c9mA:
58.9		 2z97A-4c9mA:
45.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c9m CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		4 TYR A  98
THR A 103
LEU A 252
VAL A 404
 None
GOL  A1419 (-3.8A)
HEM  A1418 (-4.0A)
GOL  A1419 (-3.5A)
 0.80A 2z97A-4c9mA:
58.9		 2z97A-4c9mA:
45.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2

(Neurospora
crassa) 		PF00929
(RNase_T)
PF13423
(UCH_1) 		4 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.69A 2z97A-4czwA:
undetectable		 2z97A-4czwA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4de8 CPS2A

(Streptococcus
pneumoniae) 		PF02916
(DNA_PPF)
PF03816
(LytR_cpsA_psr) 		4 TYR A 167
LEU A 114
VAL A 161
VAL A 133
 None
 0.98A 2z97A-4de8A:
undetectable		 2z97A-4de8A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dn7 ABC TRANSPORTER,
ATP-BINDING PROTEIN

(Methanosarcina
mazei) 		PF01458
(UPF0051) 		4 TYR A 130
THR A 146
VAL A  88
VAL A 134
 None
 0.99A 2z97A-4dn7A:
undetectable		 2z97A-4dn7A:
20.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4dxy CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		4 THR A 101
LEU A 250
VAL A 301
VAL A 402
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
None
 0.87A 2z97A-4dxyA:
52.3		 2z97A-4dxyA:
46.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e4j ARGININE DEIMINASE

(Mycoplasma
penetrans) 		PF02274
(Amidinotransf) 		4 LEU A 357
VAL A 360
VAL A 270
VAL A 301
 None
 0.68A 2z97A-4e4jA:
undetectable		 2z97A-4e4jA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ese FMN-DEPENDENT
NADH-AZOREDUCTASE

(Yersinia pestis) 		PF02525
(Flavodoxin_2) 		4 LEU A 195
VAL A 198
VAL A   4
VAL A  89
 None
 0.86A 2z97A-4eseA:
undetectable		 2z97A-4eseA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mgg MUCONATE LACTONIZING
ENZYME

(Labrenzia
aggregata) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		5 THR A 180
LEU A 164
VAL A 166
VAL A 210
VAL A 206
 None
 1.27A 2z97A-4mggA:
undetectable		 2z97A-4mggA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nz0 GENOME POLYPROTEIN

(Cardiovirus A) 		PF00680
(RdRP_1) 		4 TYR A 236
LEU A 352
VAL A 328
VAL A 337
 None
 0.98A 2z97A-4nz0A:
undetectable		 2z97A-4nz0A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o65 PUTATIVE ARCHAEAL
AMMONIA
MONOOXYGENASE
SUBUNIT B

(Candidatus
Nitrosocaldus
yellowstonensis) 		PF04744
(Monooxygenase_B) 		4 THR A 183
LEU A  73
VAL A  76
VAL A  89
 None
 0.96A 2z97A-4o65A:
undetectable		 2z97A-4o65A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o6k INTERLEUKIN 22

(Danio rerio) 		no annotation 4 TYR A 134
THR A  12
VAL A  86
VAL A  59
 None
 0.98A 2z97A-4o6kA:
undetectable		 2z97A-4o6kA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ogc HNH ENDONUCLEASE
DOMAIN PROTEIN

(Actinomyces
naeslundii) 		PF01844
(HNH) 		4 LEU A 482
VAL A 485
VAL A 700
VAL A 504
 None
 0.95A 2z97A-4ogcA:
undetectable		 2z97A-4ogcA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pqj PHOSPHATE BINDING
PROTEIN

(Pseudomonas
aeruginosa) 		PF12849
(PBP_like_2) 		4 THR A 187
LEU A 125
VAL A 214
VAL A 215
 PO4  A 401 (-3.5A)
None
None
None
 1.00A 2z97A-4pqjA:
undetectable		 2z97A-4pqjA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT

(Saccharomyces
cerevisiae) 		PF00583
(Acetyltransf_1)
PF10394
(Hat1_N) 		4 TYR A  71
VAL A  83
VAL A  98
VAL A  67
 None
 0.94A 2z97A-4pswA:
undetectable		 2z97A-4pswA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q5y MATERNAL PROTEIN
TUDOR

(Drosophila
melanogaster) 		PF00567
(TUDOR) 		4 LEU A2458
VAL A2498
VAL A2353
VAL A2364
 None
 0.94A 2z97A-4q5yA:
undetectable		 2z97A-4q5yA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qbu ZMAA

(Bacillus cereus) 		PF00698
(Acyl_transf_1) 		4 THR A 382
LEU A  98
VAL A 258
VAL A 352
 None
 0.74A 2z97A-4qbuA:
undetectable		 2z97A-4qbuA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r0c ABGT PUTATIVE
TRANSPORTER FAMILY

(Alcanivorax
borkumensis) 		PF03806
(ABG_transport) 		4 TYR A 468
THR A 228
VAL A 119
VAL A 122
 None
 0.96A 2z97A-4r0cA:
undetectable		 2z97A-4r0cA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4re2 BETA-MANNOSIDASE/BET
A-GLUCOSIDASE

(Oryza sativa) 		PF00232
(Glyco_hydro_1) 		4 THR A  26
VAL A 455
VAL A  33
VAL A  67
 None
 0.97A 2z97A-4re2A:
undetectable		 2z97A-4re2A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rsi STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
2
STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
4

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF06470
(SMC_hinge)
PF06470
(SMC_hinge) 		4 THR B 820
VAL A 576
VAL A 527
VAL A 526
 None
 0.95A 2z97A-4rsiB:
undetectable		 2z97A-4rsiB:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rzi 3-KETOACYL-ACYL
CARRIER PROTEIN
REDUCTASE

(Synechocystis
sp. PCC 6803) 		no annotation 4 TYR B  77
LEU B   6
VAL B 130
VAL B  80
 None
 0.99A 2z97A-4rziB:
undetectable		 2z97A-4rziB:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4us5 LUCIFERASE-LIKE
MONOOXYGENASE

(Streptomyces
bottropensis) 		PF00296
(Bac_luciferase) 		4 THR A 238
LEU A 254
VAL A 222
VAL A 309
 None
None
None
NA  A1340 (-3.7A)
 0.90A 2z97A-4us5A:
undetectable		 2z97A-4us5A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xcg THERMOSOME SUBUNIT
BETA

(Sulfolobus
solfataricus) 		PF00118
(Cpn60_TCP1) 		4 THR B 337
VAL B 299
VAL B 230
VAL B 370
 None
 0.98A 2z97A-4xcgB:
undetectable		 2z97A-4xcgB:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z8t AVRRXO1-ORF1

(Xanthomonas
oryzae) 		no annotation 4 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.86A 2z97A-4z8tA:
undetectable		 2z97A-4z8tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zk7 DIVALENT-CATION
TOLERANCE PROTEIN
CUTA

(Thermus
thermophilus) 		PF03091
(CutA1) 		4 LEU M  74
VAL M  71
VAL M  31
VAL M  57
 None
 0.98A 2z97A-4zk7M:
undetectable		 2z97A-4zk7M:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zpm PROTEIN PCDHAC2

(Mus musculus) 		PF00028
(Cadherin)
PF08266
(Cadherin_2) 		4 LEU A 254
VAL A 293
VAL A 234
VAL A 235
 None
 0.87A 2z97A-4zpmA:
undetectable		 2z97A-4zpmA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dx5 METHIONINE
GAMMA-LYASE

(Clostridium
sporogenes) 		PF01053
(Cys_Met_Meta_PP) 		4 LEU A 139
VAL A 142
VAL A 184
VAL A 153
 None
 0.80A 2z97A-5dx5A:
undetectable		 2z97A-5dx5A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5isu LMO0135 PROTEIN

(Listeria
monocytogenes) 		PF00496
(SBP_bac_5) 		4 THR A 169
VAL A 122
VAL A  99
VAL A 155
 None
 0.83A 2z97A-5isuA:
undetectable		 2z97A-5isuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lw3 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6

(Azotobacter
vinelandii) 		no annotation 4 TYR A 244
VAL A 262
VAL A 224
VAL A 254
 None
 0.85A 2z97A-5lw3A:
undetectable		 2z97A-5lw3A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus) 		no annotation 4 THR A 134
LEU A 232
VAL A 241
VAL A 191
 None
 0.94A 2z97A-5mqzA:
undetectable		 2z97A-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n38 E3 UBIQUITIN-PROTEIN
LIGASE PARKIN,E3
UBIQUITIN-PROTEIN
LIGASE PARKIN

(Homo sapiens) 		PF00240
(ubiquitin)
PF01485
(IBR) 		4 THR A  21
VAL A  29
VAL A  67
VAL A   5
 None
 0.95A 2z97A-5n38A:
undetectable		 2z97A-5n38A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nmw FLAVIN-CONTAINING
MONOOXYGENASE

(Zonocerus
variegatus) 		no annotation 4 THR A  15
VAL A 318
VAL A  27
VAL A   4
 None
 0.99A 2z97A-5nmwA:
undetectable		 2z97A-5nmwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x5h CYSTATHIONINE
BETA-LYASES/CYSTATHI
ONINE
GAMMA-SYNTHASES

(Corynebacterium
glutamicum) 		PF01053
(Cys_Met_Meta_PP) 		4 LEU A 376
VAL A 379
VAL A 281
VAL A 308
 None
None
GOL  A 402 (-4.0A)
None
 0.91A 2z97A-5x5hA:
undetectable		 2z97A-5x5hA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bld CYTOCHROME P450
268A2 CYP268A2

(Mycobacterium
marinum) 		no annotation 4 LEU A 256
VAL A 259
VAL A 308
VAL A 409
 HEM  A 501 ( 4.8A)
DXJ  A 502 (-4.5A)
HEM  A 501 ( 4.6A)
None
 0.78A 2z97A-6bldA:
42.4		 2z97A-6bldA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d1q RNA
PYROPHOSPHOHYDROLASE

(Escherichia
coli) 		no annotation 4 THR B  71
VAL B  14
VAL B 154
VAL B 155
 None
 0.93A 2z97A-6d1qB:
undetectable		 2z97A-6d1qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6glc E3 UBIQUITIN-PROTEIN
LIGASE PARKIN

(Homo sapiens) 		no annotation 4 THR A  21
VAL A  29
VAL A  67
VAL A   5
 None
 1.00A 2z97A-6glcA:
undetectable		 2z97A-6glcA:
undetectable