SIMILAR PATTERNS OF AMINO ACIDS FOR 2YVL_B_SAMB602_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b7e PROTEIN (TRANSPOSASE
INHIBITOR PROTEIN
FROM TN5)

(Escherichia
coli) 		PF01609
(DDE_Tnp_1)
PF02281
(Dimer_Tnp_Tn5) 		3 GLU A 326
ASP A 188
TYR A 319
 None
 0.79A 2yvlB-1b7eA:
2.2		 2yvlB-1b7eA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c7o CYSTALYSIN

(Treponema
denticola) 		PF00155
(Aminotran_1_2) 		3 GLU A 343
ASP A 355
TYR A 124
 None
PPG  A1500 ( 4.0A)
None
 0.69A 2yvlB-1c7oA:
3.5		 2yvlB-1c7oA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eo6 GOLGI-ASSOCIATED
ATPASE ENHANCER OF
16 KD

(Bos taurus) 		PF02991
(Atg8) 		3 GLU A  17
ASP A 102
TYR A 106
 None
 0.88A 2yvlB-1eo6A:
undetectable		 2yvlB-1eo6A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f59 IMPORTIN BETA-1

(Homo sapiens) 		PF03810
(IBN_N)
PF13513
(HEAT_EZ) 		3 GLU A 214
ASP A 210
TYR A 248
 None
 0.78A 2yvlB-1f59A:
undetectable		 2yvlB-1f59A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f99 R-PHYCOCYANIN

(Polysiphonia
urceolata) 		PF00502
(Phycobilisome) 		3 GLU A   7
ASP A 108
TYR A 156
 None
 0.74A 2yvlB-1f99A:
undetectable		 2yvlB-1f99A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gnu GABARAP

(Homo sapiens) 		PF02991
(Atg8) 		3 GLU A  17
ASP A 102
TYR A 106
 None
 0.73A 2yvlB-1gnuA:
undetectable		 2yvlB-1gnuA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h7k CATALASE

(Proteus
mirabilis) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		3 GLU A 444
ASP A 178
TYR A 133
 None
 0.88A 2yvlB-1h7kA:
undetectable		 2yvlB-1h7kA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i1q ANTHRANILATE
SYNTHASE COMPONENT I

(Salmonella
enterica) 		PF00425
(Chorismate_bind)
PF04715
(Anth_synt_I_N) 		3 GLU A 322
ASP A 463
TYR A 292
 None
TRP  A1001 (-4.3A)
TRP  A1001 (-3.9A)
 0.87A 2yvlB-1i1qA:
undetectable		 2yvlB-1i1qA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iq0 ARGINYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1) 		3 GLU A 513
ASP A 511
TYR A  36
 None
 0.73A 2yvlB-1iq0A:
undetectable		 2yvlB-1iq0A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l5a AMIDE SYNTHASE

(Vibrio cholerae) 		PF00668
(Condensation) 		3 GLU A 360
ASP A 202
TYR A  15
 None
 0.79A 2yvlB-1l5aA:
undetectable		 2yvlB-1l5aA:
18.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1o54 SAM-DEPENDENT
O-METHYLTRANSFERASE

(Thermotoga
maritima) 		PF08704
(GCD14) 		3 GLU A 132
ASP A 160
TYR A 183
 None
 0.77A 2yvlB-1o54A:
27.7		 2yvlB-1o54A:
35.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q1q SULFOTRANSFERASE
FAMILY, CYTOSOLIC,
2B, MEMBER 1 ISOFORM
A

(Homo sapiens) 		PF00685
(Sulfotransfer_1) 		3 GLU A 196
ASP A 295
TYR A 282
 None
 0.59A 2yvlB-1q1qA:
undetectable		 2yvlB-1q1qA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q20 SULFOTRANSFERASE
FAMILY, CYTOSOLIC,
2B, MEMBER 1 ISOFORM
B

(Homo sapiens) 		PF00685
(Sulfotransfer_1) 		3 GLU A 211
ASP A 310
TYR A 297
 None
 0.65A 2yvlB-1q20A:
undetectable		 2yvlB-1q20A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qhg ATP-DEPENDENT
HELICASE PCRA

(Geobacillus
stearothermophilus) 		PF00580
(UvrD-helicase)
PF13361
(UvrD_C) 		3 GLU A 241
ASP A 273
TYR A 233
 None
 0.66A 2yvlB-1qhgA:
2.8		 2yvlB-1qhgA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qhh PROTEIN (PCRA
(SUBUNIT))

(Geobacillus
stearothermophilus) 		PF00580
(UvrD-helicase)
PF13361
(UvrD_C) 		3 GLU B 241
ASP B 273
TYR B 233
 None
 0.87A 2yvlB-1qhhB:
undetectable		 2yvlB-1qhhB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uh9 HIZOPUSPEPSIN I

(Rhizopus
microsporus) 		PF00026
(Asp) 		3 GLU A  16
ASP A  35
TYR A  77
 None
 0.87A 2yvlB-1uh9A:
undetectable		 2yvlB-1uh9A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uyv ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF01039
(Carboxyl_trans) 		3 GLU A1541
ASP A1588
TYR A1507
 None
 0.87A 2yvlB-1uyvA:
undetectable		 2yvlB-1uyvA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wk4 TTK003001606

(Thermus
thermophilus) 		PF00583
(Acetyltransf_1) 		3 GLU A  69
ASP A  20
TYR A  40
 None
 0.87A 2yvlB-1wk4A:
2.8		 2yvlB-1wk4A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xje RIBONUCLEOTIDE
REDUCTASE,
B12-DEPENDENT

(Thermotoga
maritima) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC) 		3 GLU A 468
ASP A 466
TYR A 590
 None
 0.72A 2yvlB-1xjeA:
undetectable		 2yvlB-1xjeA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xup GLYCEROL KINASE

(Enterococcus
casseliflavus) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		3 GLU O 479
ASP O 425
TYR O 387
 None
 0.75A 2yvlB-1xupO:
undetectable		 2yvlB-1xupO:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xw8 UPF0271 PROTEIN YBGL

(Escherichia
coli) 		PF03746
(LamB_YcsF) 		3 GLU A 143
ASP A 121
TYR A 151
 None
 0.81A 2yvlB-1xw8A:
undetectable		 2yvlB-1xw8A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yrz XYLAN
BETA-1,4-XYLOSIDASE

(Bacillus
halodurans) 		PF04616
(Glyco_hydro_43) 		3 GLU A1163
ASP A1135
TYR A1199
 None
 0.84A 2yvlB-1yrzA:
undetectable		 2yvlB-1yrzA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c27 MYCOTHIOL SYNTHASE

(Mycobacterium
tuberculosis) 		PF00583
(Acetyltransf_1) 		3 GLU A  79
ASP A 305
TYR A 282
 MA8  A1312 ( 4.9A)
None
MA8  A1312 (-4.4A)
 0.85A 2yvlB-2c27A:
2.7		 2yvlB-2c27A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c9k PESTICIDAL CRYSTAL
PROTEIN CRY4AA

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		3 GLU A 258
ASP A 314
TYR A 250
 None
 0.84A 2yvlB-2c9kA:
undetectable		 2yvlB-2c9kA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ce1 CYTOCHROME C6

(Arabidopsis
thaliana) 		PF13442
(Cytochrome_CBB3) 		3 GLU A  83
ASP A  81
TYR A  54
 None
 0.76A 2yvlB-2ce1A:
undetectable		 2yvlB-2ce1A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d1q LUCIFERIN
4-MONOOXYGENASE

(Luciola
cruciata) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		3 GLU A  88
ASP A  52
TYR A 282
 None
 0.67A 2yvlB-2d1qA:
undetectable		 2yvlB-2d1qA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION

(Escherichia
virus T4) 		PF09414
(RNA_ligase) 		3 GLU A 296
ASP A 115
TYR A  75
 None
 0.78A 2yvlB-2hvqA:
undetectable		 2yvlB-2hvqA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o36 THIMET
OLIGOPEPTIDASE

(Homo sapiens) 		PF01432
(Peptidase_M3) 		3 GLU A 111
ASP A 109
TYR A  75
 None
 0.55A 2yvlB-2o36A:
undetectable		 2yvlB-2o36A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o3e NEUROLYSIN

(Rattus
norvegicus) 		PF01432
(Peptidase_M3) 		3 GLU A 112
ASP A 110
TYR A  76
 None
 0.63A 2yvlB-2o3eA:
undetectable		 2yvlB-2o3eA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vml PHYCOCYANIN ALPHA
CHAIN

(Gloeobacter
violaceus) 		PF00502
(Phycobilisome) 		3 GLU A   7
ASP A 106
TYR A 156
 None
 0.81A 2yvlB-2vmlA:
undetectable		 2yvlB-2vmlA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vr5 GLYCOGEN OPERON
PROTEIN GLGX

(Sulfolobus
solfataricus) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		3 GLU A 354
ASP A 346
TYR A  18
 GOL  A1724 (-4.1A)
None
None
 0.88A 2yvlB-2vr5A:
undetectable		 2yvlB-2vr5A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w6d DYNAMIN FAMILY
PROTEIN

(Nostoc
punctiforme) 		PF00350
(Dynamin_N) 		3 GLU A  15
ASP A  13
TYR A 691
 None
 0.86A 2yvlB-2w6dA:
undetectable		 2yvlB-2w6dA:
18.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2yvl HYPOTHETICAL PROTEIN

(Aquifex
aeolicus) 		PF08704
(GCD14) 		3 GLU A 120
ASP A 148
TYR A 172
 SAM  A 601 (-2.7A)
SAM  A 601 (-3.1A)
SAM  A 601 (-4.0A)
 0.19A 2yvlB-2yvlA:
38.9		 2yvlB-2yvlA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3af5 PUTATIVE
UNCHARACTERIZED
PROTEIN PH1404

(Pyrococcus
horikoshii) 		PF07521
(RMMBL)
PF10996
(Beta-Casp)
PF16661
(Lactamase_B_6)
PF17214
(KH_7) 		3 GLU A 464
ASP A 286
TYR A 472
 None
 0.88A 2yvlB-3af5A:
2.5		 2yvlB-3af5A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b40 PROBABLE DIPEPTIDASE

(Pseudomonas
aeruginosa) 		PF01244
(Peptidase_M19) 		3 GLU A 282
ASP A 280
TYR A 375
 None
 0.88A 2yvlB-3b40A:
undetectable		 2yvlB-3b40A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ce2 PUTATIVE PEPTIDASE

(Chlamydia
abortus) 		PF01432
(Peptidase_M3)
PF08439
(Peptidase_M3_N) 		3 GLU A 232
ASP A 514
TYR A 312
 None
 0.61A 2yvlB-3ce2A:
undetectable		 2yvlB-3ce2A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3efm FERRIC ALCALIGIN
SIDEROPHORE RECEPTOR

(Bordetella
pertussis) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 GLU A 264
ASP A 290
TYR A 268
 None
 0.81A 2yvlB-3efmA:
undetectable		 2yvlB-3efmA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE

(Archaeoglobus
fulgidus) 		PF01874
(CitG) 		3 GLU A 244
ASP A 246
TYR A 206
 None
 0.79A 2yvlB-3h9pA:
undetectable		 2yvlB-3h9pA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k50 PUTATIVE S41
PROTEASE

(Bacteroides
fragilis) 		PF03572
(Peptidase_S41) 		3 GLU A 292
ASP A 288
TYR A  52
 None
 0.82A 2yvlB-3k50A:
undetectable		 2yvlB-3k50A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kvs C-PHYCOCYANIN ALPHA
CHAIN

(Galdieria
sulphuraria) 		PF00502
(Phycobilisome) 		3 GLU A   7
ASP A 108
TYR A 156
 None
 0.67A 2yvlB-3kvsA:
undetectable		 2yvlB-3kvsA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lw0 INSULIN-LIKE GROWTH
FACTOR 1 RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 GLU A1050
ASP A1135
TYR A1165
 CCX  A   1 ( 4.3A)
None
None
 0.77A 2yvlB-3lw0A:
undetectable		 2yvlB-3lw0A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pdt MYOSIN HEAVY CHAIN
KINASE A

(Dictyostelium
discoideum) 		PF02816
(Alpha_kinase) 		3 GLU A 713
ASP A 663
TYR A 647
 None
 0.61A 2yvlB-3pdtA:
undetectable		 2yvlB-3pdtA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6

(Saccharomyces
cerevisiae) 		PF14635
(HHH_7)
PF14639
(YqgF)
PF14641
(HTH_44)
PF14878
(DLD) 		3 GLU A 450
ASP A 445
TYR A 472
 None
 0.78A 2yvlB-3psiA:
undetectable		 2yvlB-3psiA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pz9 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE. GLYCOSYL
HYDROLASE FAMILY 5

(Thermotoga
petrophila) 		PF00150
(Cellulase) 		3 GLU A 357
ASP A  56
TYR A 114
 None
 0.60A 2yvlB-3pz9A:
1.7		 2yvlB-3pz9A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsz RICIN B LECTIN

(Ruminiclostridium
thermocellum) 		PF04616
(Glyco_hydro_43)
PF14200
(RicinB_lectin_2) 		3 GLU A 207
ASP A 186
TYR A 240
 None
 0.72A 2yvlB-3vszA:
undetectable		 2yvlB-3vszA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wap AUTOPHAGY-RELATED
PROTEIN 13,
MICROTUBULE-ASSOCIAT
ED PROTEINS 1A/1B
LIGHT CHAIN 3C

(Homo sapiens) 		PF02991
(Atg8) 		3 GLU A  34
ASP A 121
TYR A 125
 None
 0.60A 2yvlB-3wapA:
undetectable		 2yvlB-3wapA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wc3 ENDO-1,
4-BETA-GLUCANASE

(Eisenia fetida) 		PF00759
(Glyco_hydro_9) 		3 GLU A  39
ASP A 435
TYR A 226
 None
GOL  A 509 ( 4.3A)
TRS  A 503 (-4.2A)
 0.79A 2yvlB-3wc3A:
undetectable		 2yvlB-3wc3A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wih ANTI-HUMAN ROBO1
ANTIBODY B2212A FAB
HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 GLU H   1
ASP H 107
TYR H  32
 None
 0.77A 2yvlB-3wihH:
undetectable		 2yvlB-3wihH:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zuz PROTEIN SHQ1

(Saccharomyces
cerevisiae) 		PF04925
(SHQ1) 		3 GLU A 192
ASP A 189
TYR A 423
 None
 0.79A 2yvlB-3zuzA:
undetectable		 2yvlB-3zuzA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b16 CHITINASE LIKE
LECTIN

(Tamarindus
indica) 		PF00704
(Glyco_hydro_18) 		3 GLU A  42
ASP A  53
TYR A  46
 None
 0.88A 2yvlB-4b16A:
undetectable		 2yvlB-4b16A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cd8 ENDO-BETA-1,4-MANNAN
ASE

(Alicyclobacillus
acidocaldarius) 		no annotation 3 GLU A  75
ASP A  73
TYR A 134
 None
 0.68A 2yvlB-4cd8A:
undetectable		 2yvlB-4cd8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d05 ATP-DEPENDENT DNA
LIGASE

(Psychromonas
sp. SP041) 		PF01068
(DNA_ligase_A_M)
PF14743
(DNA_ligase_OB_2) 		3 GLU A 221
ASP A 219
TYR A 194
 None
 0.77A 2yvlB-4d05A:
undetectable		 2yvlB-4d05A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0t C-PHYCOCYANIN ALPHA
CHAIN

(Synechocystis
sp. PCC 6803) 		PF00502
(Phycobilisome) 		3 GLU A   7
ASP A 108
TYR A 168
 None
 0.77A 2yvlB-4f0tA:
undetectable		 2yvlB-4f0tA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gzu FERM, RHOGEF AND
PLECKSTRIN
DOMAIN-CONTAINING
PROTEIN 2

(Mus musculus) 		PF00169
(PH)
PF00621
(RhoGEF) 		3 GLU A 558
ASP A 556
TYR A 674
 None
 0.82A 2yvlB-4gzuA:
undetectable		 2yvlB-4gzuA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h6y FERM, RHOGEF AND
PLECKSTRIN
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00169
(PH)
PF00621
(RhoGEF) 		3 GLU A 560
ASP A 558
TYR A 675
 None
 0.82A 2yvlB-4h6yA:
undetectable		 2yvlB-4h6yA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i3f SERINE HYDROLASE
CCSP0084

(Cycloclasticus
sp. P1) 		PF12697
(Abhydrolase_6) 		3 GLU A 214
ASP A 212
TYR A 240
 None
 0.55A 2yvlB-4i3fA:
2.9		 2yvlB-4i3fA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i5v 5',5'''-P-1,P-4-TETR
APHOSPHATE
PHOSPHORYLASE 2

(Saccharomyces
cerevisiae) 		PF09830
(ATP_transf) 		3 GLU A 217
ASP A 119
TYR A  87
 None
 0.88A 2yvlB-4i5vA:
undetectable		 2yvlB-4i5vA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l7a UNCHARACTERIZED
PROTEIN

(Bacteroides
caccae) 		PF15890
(Peptidase_Mx1) 		3 GLU A  48
ASP A  50
TYR A  67
 None
 0.88A 2yvlB-4l7aA:
undetectable		 2yvlB-4l7aA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oy2 TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 7

(Saccharomyces
cerevisiae) 		PF04658
(TAFII55_N) 		3 GLU B 213
ASP B 211
TYR B 270
 None
 0.78A 2yvlB-4oy2B:
undetectable		 2yvlB-4oy2B:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p5y GLYCOSYL HYDROLASE,
FAMILY
31/FIBRONECTIN TYPE
III DOMAIN PROTEIN

(Clostridium
perfringens) 		PF00754
(F5_F8_type_C) 		3 GLU A 156
ASP A  75
TYR A 160
 None
 0.81A 2yvlB-4p5yA:
undetectable		 2yvlB-4p5yA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qhq LIPOPROTEIN

(Burkholderia
cenocepacia) 		PF03180
(Lipoprotein_9) 		3 GLU A  43
ASP A  41
TYR A 109
 PEG  A 302 (-3.2A)
MET  A 301 ( 4.7A)
None
 0.79A 2yvlB-4qhqA:
undetectable		 2yvlB-4qhqA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qqs GLYCOSIDE HYDROLASE
FAMILY 43

(Halothermothrix
orenii) 		PF04616
(Glyco_hydro_43) 		3 GLU A 162
ASP A 132
TYR A 206
 None
 0.81A 2yvlB-4qqsA:
undetectable		 2yvlB-4qqsA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r5o QUINONPROTEIN
ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF16819
(DUF5074)
PF16820
(PKD_3) 		3 GLU A 389
ASP A 367
TYR A 371
 None
 0.86A 2yvlB-4r5oA:
undetectable		 2yvlB-4r5oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xkm XYLOSE ISOMERASE

(Bacteroides
thetaiotaomicron) 		no annotation 3 GLU A 118
ASP A 177
TYR A 221
 None
 0.82A 2yvlB-4xkmA:
undetectable		 2yvlB-4xkmA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yco TRNA-DIHYDROURIDINE
SYNTHASE C

(Escherichia
coli) 		PF01207
(Dus) 		3 GLU A   9
ASP A  13
TYR A 268
 U  D  16 (-4.6A)
None
None
 0.79A 2yvlB-4ycoA:
1.8		 2yvlB-4ycoA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zdv MICROTUBULE-ASSOCIAT
ED PROTEINS 1A/1B
LIGHT CHAIN 3A

(Homo sapiens) 		PF02991
(Atg8) 		3 GLU A  19
ASP A 106
TYR A 110
 None
 0.78A 2yvlB-4zdvA:
undetectable		 2yvlB-4zdvA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a0k LABDANE-RELATED
DITERPENE SYNTHASE

(Streptomyces
sp.) 		no annotation 3 GLU A 238
ASP A 231
TYR A 180
 None
 0.86A 2yvlB-5a0kA:
undetectable		 2yvlB-5a0kA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b4w PLEXIN-B1

(Homo sapiens) 		PF01403
(Sema)
PF01437
(PSI) 		3 GLU A 291
ASP A 330
TYR A 229
 None
 0.85A 2yvlB-5b4wA:
undetectable		 2yvlB-5b4wA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bn4 V-TYPE ATP SYNTHASE
ALPHA CHAIN
NEQ263

(Nanoarchaeum
equitans;
Nanoarchaeum
equitans) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N)
PF16886
(ATP-synt_ab_Xtn)
PF00006
(ATP-synt_ab) 		3 GLU B 380
ASP B 319
TYR A 410
 None
 0.87A 2yvlB-5bn4B:
2.6		 2yvlB-5bn4B:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dps PLECKSTRIN HOMOLOGY
DOMAIN-CONTAINING
FAMILY M MEMBER
1,GAMMA-AMINOBUTYRIC
ACID
RECEPTOR-ASSOCIATED
PROTEIN

(Homo sapiens) 		PF02991
(Atg8) 		3 GLU A  24
ASP A 109
TYR A 113
 None
 0.75A 2yvlB-5dpsA:
undetectable		 2yvlB-5dpsA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dpt PLECKSTRIN HOMOLOGY
DOMAIN-CONTAINING
FAMILY M MEMBER 1,
GAMMA-AMINOBUTYRIC
ACID
RECEPTOR-ASSOCIATED
PROTEIN-LIKE
1,GAMMA-AMINOBUTYRIC
ACID
RECEPTOR-ASSOCIATED
PROTEIN-LIKE 1

(Homo sapiens) 		PF02991
(Atg8) 		3 GLU A  24
ASP A 109
TYR A 113
 None
 0.78A 2yvlB-5dptA:
undetectable		 2yvlB-5dptA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5erm FUSICOCCADIENE
SYNTHASE

(Diaporthe
amygdali) 		no annotation 3 GLU A 290
ASP A 307
TYR A 311
 None
 0.79A 2yvlB-5ermA:
undetectable		 2yvlB-5ermA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7s GLYCOSIDE HYDROLASE
FAMILY 31

(Trueperella
pyogenes) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		3 GLU A 221
ASP A 661
TYR A 693
 None
 0.78A 2yvlB-5f7sA:
undetectable		 2yvlB-5f7sA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fww KREMEN PROTEIN 1
DICKKOPF-RELATED
PROTEIN 1

(Homo sapiens;
Homo sapiens) 		PF00051
(Kringle)
PF00431
(CUB)
PF01822
(WSC)
no annotation 		3 GLU B 185
ASP B 201
TYR C 238
 None
 0.87A 2yvlB-5fwwB:
undetectable		 2yvlB-5fwwB:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fzp DISPASE
AUTOLYSIS-INDUCING
PROTEIN

(Streptomyces
mobaraensis) 		no annotation 3 GLU A 292
ASP A 303
TYR A 300
 None
 0.84A 2yvlB-5fzpA:
undetectable		 2yvlB-5fzpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE

(Thermus
thermophilus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 GLU A 267
ASP A 392
TYR A 288
 MPD  A1466 (-3.8A)
None
None
 0.86A 2yvlB-5g3fA:
undetectable		 2yvlB-5g3fA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ik2 ATP SYNTHASE SUBUNIT
ALPHA

(Caldalkalibacillus
thermarum) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		3 GLU A 486
ASP A 488
TYR A 438
 None
 0.80A 2yvlB-5ik2A:
2.5		 2yvlB-5ik2A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jo7 VETISPIRADIENE
SYNTHASE 1

(Hyoscyamus
muticus) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		3 GLU A 459
ASP A 452
TYR A 401
 None
 0.67A 2yvlB-5jo7A:
undetectable		 2yvlB-5jo7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacter
diazotrophicus) 		PF00148
(Oxidored_nitro) 		3 GLU A 338
ASP A 333
TYR A 237
 None
 0.85A 2yvlB-5kojA:
undetectable		 2yvlB-5kojA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l6o EPHRIN TYPE-B
RECEPTOR 3

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 GLU A 682
ASP A 758
TYR A 792
 None
 0.73A 2yvlB-5l6oA:
undetectable		 2yvlB-5l6oA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nec TONB-DEPENDENT
SIDEROPHORE RECEPTOR

(Pseudomonas
aeruginosa) 		no annotation 3 GLU A 531
ASP A 558
TYR A 535
 None
None
C8E  A 802 ( 3.9A)
 0.87A 2yvlB-5necA:
undetectable		 2yvlB-5necA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ng6 CRISPR-ASSOCIATED
ENDONUCLEASE CPF1

(Francisella
tularensis) 		no annotation 3 GLU A1225
ASP A1253
TYR A 925
 None
 0.81A 2yvlB-5ng6A:
undetectable		 2yvlB-5ng6A:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nhb XYLOSE ISOMERASE

(Piromyces sp.
E2) 		no annotation 3 GLU A 117
ASP A 176
TYR A 220
 None
 0.81A 2yvlB-5nhbA:
undetectable		 2yvlB-5nhbA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5no7 LYTIC POLYSACCHARIDE
MONOOXYGENASE

(Trametes
cinnabarina) 		no annotation 3 GLU A 173
ASP A 238
TYR A 250
 None
NAG  A 320 (-4.0A)
None
 0.74A 2yvlB-5no7A:
undetectable		 2yvlB-5no7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oee LARGE SUBUNIT
TERMINASE

(Phage D6E) 		no annotation 3 GLU A 303
ASP A 301
TYR A 264
 None
 0.69A 2yvlB-5oeeA:
3.4		 2yvlB-5oeeA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ohk UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE
30,UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE
30,UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30

(Homo sapiens) 		PF00443
(UCH) 		3 GLU A 159
ASP A 161
TYR A 495
 AYE  A 602 (-3.5A)
None
None
 0.78A 2yvlB-5ohkA:
undetectable		 2yvlB-5ohkA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ook PHYCOCYANIN, ALPHA
SUBUNIT

(Acaryochloris
marina) 		no annotation 3 GLU A   7
ASP A 108
TYR A 168
 PEG  A 202 (-2.9A)
None
None
 0.86A 2yvlB-5ookA:
undetectable		 2yvlB-5ookA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tou PHYCOCYANIN ALPHA-1
SUBUNIT

(Pseudanabaena
sp. lw0831) 		no annotation 3 GLU C   7
ASP C 108
TYR C 156
 None
 0.80A 2yvlB-5touC:
undetectable		 2yvlB-5touC:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tu0 LMO2125 PROTEIN

(Listeria
monocytogenes) 		PF13416
(SBP_bac_8) 		3 GLU A 410
ASP A 216
TYR A 205
 None
 0.78A 2yvlB-5tu0A:
undetectable		 2yvlB-5tu0A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u2o J30 CCH

(Thermobacillus
composti) 		no annotation 3 GLU A 203
ASP A 527
TYR A 306
 None
GOL  A 603 ( 4.5A)
GOL  A 603 ( 4.2A)
 0.62A 2yvlB-5u2oA:
undetectable		 2yvlB-5u2oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uvk C-PHYCOCYANIN ALPHA
CHAIN

(Thermosynechococcus
elongatus) 		PF00502
(Phycobilisome) 		3 GLU A   7
ASP A 108
TYR A 156
 None
 0.87A 2yvlB-5uvkA:
undetectable		 2yvlB-5uvkA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x8r 30S RIBOSOMAL
PROTEIN S6 ALPHA,
CHLOROPLASTIC

(Spinacia
oleracea) 		no annotation 3 GLU f 122
ASP f 117
TYR f 168
 None
 0.77A 2yvlB-5x8rf:
undetectable		 2yvlB-5x8rf:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxu RIBOSOMAL PROTEIN
US2
RIBOSOMAL PROTEIN
ES21

(Toxoplasma
gondii;
Toxoplasma
gondii) 		PF00318
(Ribosomal_S2)
PF01249
(Ribosomal_S21e) 		3 GLU V  63
ASP V  65
TYR A  38
 None
 0.86A 2yvlB-5xxuV:
undetectable		 2yvlB-5xxuV:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yf0 -

(-) 		no annotation 3 GLU A 229
ASP A 295
TYR A 324
 SAM  A 505 (-2.9A)
SAM  A 505 (-3.6A)
None
 0.83A 2yvlB-5yf0A:
14.8		 2yvlB-5yf0A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yqw PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Vibrio harveyi) 		no annotation 3 GLU A  43
ASP A 415
TYR A 455
 None
 0.79A 2yvlB-5yqwA:
undetectable		 2yvlB-5yqwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6az1 RIBOSOMAL PROTEIN
S4E

(Leishmania
donovani) 		no annotation 3 GLU E  88
ASP E  85
TYR E  79
 None
 0.67A 2yvlB-6az1E:
undetectable		 2yvlB-6az1E:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6az1 RIBOSOMAL PROTEIN S2
RIBOSOMAL PROTEIN
S21E

(Leishmania
donovani;
Leishmania
donovani) 		no annotation
no annotation 		3 GLU Y  68
ASP Y  70
TYR B  40
 None
 0.85A 2yvlB-6az1Y:
undetectable		 2yvlB-6az1Y:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6epc PROTEASOME (PROSOME,
MACROPAIN) 26S
SUBUNIT, NON-ATPASE,
12

(Rattus
norvegicus) 		no annotation 3 GLU P 346
ASP P 339
TYR P 273
 None
 0.79A 2yvlB-6epcP:
undetectable		 2yvlB-6epcP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eu9 RETINOIC ACID
RECEPTOR

(Platynereis
dumerilii) 		no annotation 3 GLU A 326
ASP A 450
TYR A 490
 None
 0.83A 2yvlB-6eu9A:
undetectable		 2yvlB-6eu9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fwf NITRIC-OXIDE
REDUCTASE

(Neisseria
meningitidis) 		no annotation 3 GLU A 218
ASP A  86
TYR A 155
 None
 0.85A 2yvlB-6fwfA:
undetectable		 2yvlB-6fwfA:
undetectable