SIMILAR PATTERNS OF AMINO ACIDS FOR 2YGN_A_PCFA1179_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a5z | L-LACTATEDEHYDROGENASE (Thermotogamaritima) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | LEU A 150ILE A 95LEU A 40MET A 22VAL A 298 | None | 1.10A | 2ygnA-1a5zA:undetectable | 2ygnA-1a5zA:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ikp | EXOTOXIN A (Pseudomonasaeruginosa) |
PF09009(Exotox-A_cataly)PF09101(Exotox-A_bind)PF09102(Exotox-A_target) | 5 | LEU A 49ILE A 66ARG A 154ILE A 167MET A 47 | NoneNone CL A 701 (-4.1A)NoneNone | 1.12A | 2ygnA-1ikpA:0.0 | 2ygnA-1ikpA:15.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1klp | MEROMYCOLATEEXTENSION ACYLCARRIER PROTEIN (Mycobacteriumtuberculosis) |
PF00550(PP-binding) | 5 | ILE A 16LEU A 37ILE A 27MET A 44VAL A 57 | None | 1.01A | 2ygnA-1klpA:undetectable | 2ygnA-1klpA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ogo | DEXTRANASE (Talaromycesminioluteus) |
PF03718(Glyco_hydro_49)PF17433(Glyco_hydro_49N) | 5 | ILE X 494ILE X 526MET X 423VAL X 479VAL X 482 | None | 1.08A | 2ygnA-1ogoX:0.0 | 2ygnA-1ogoX:13.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pe9 | PECTATE LYASE A (Dickeyachrysanthemi) |
PF00544(Pec_lyase_C) | 5 | LEU A 361ILE A 123ILE A 162ILE A 106VAL A 116 | None | 1.04A | 2ygnA-1pe9A:undetectable | 2ygnA-1pe9A:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q9j | POLYKETIDE SYNTHASEASSOCIATED PROTEIN 5 (Mycobacteriumtuberculosis) |
PF00668(Condensation)PF16911(PapA_C) | 5 | LEU A 285ILE A 307LEU A 303ARG A 253ILE A 300 | None | 1.13A | 2ygnA-1q9jA:0.0 | 2ygnA-1q9jA:16.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qhv | PROTEIN (ADENOVIRUSFIBRE) (HumanmastadenovirusC) |
PF00541(Adeno_knob) | 5 | ILE A 534LEU A 536ILE A 516MET A 553PHE A 555 | None | 1.07A | 2ygnA-1qhvA:0.0 | 2ygnA-1qhvA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qvr | CLPB PROTEIN (Thermusthermophilus) |
PF00004(AAA)PF02861(Clp_N)PF07724(AAA_2)PF10431(ClpB_D2-small) | 5 | ILE A 266LEU A 224ARG A 189ILE A 183VAL A 327 | None | 1.11A | 2ygnA-1qvrA:undetectable | 2ygnA-1qvrA:9.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1twy | ABC TRANSPORTER,PERIPLASMICSUBSTRATE-BINDINGPROTEIN (Vibrio cholerae) |
PF12727(PBP_like) | 5 | ILE A 126LEU A 118ILE A 131ILE A 216VAL A 194 | None | 1.07A | 2ygnA-1twyA:undetectable | 2ygnA-1twyA:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u2v | ARP2/3 COMPLEX 34KDASUBUNIT (Bos taurus) |
PF04045(P34-Arc) | 5 | LEU D 207ILE D 223LEU D 251MET D 182PHE D 200 | None | 1.10A | 2ygnA-1u2vD:0.0 | 2ygnA-1u2vD:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uf2 | CORE PROTEIN P3 (Rice dwarfvirus) |
PF09231(RDV-p3) | 5 | LEU A 118ILE A 706LEU A 710ILE A 754VAL A 761 | None | 0.95A | 2ygnA-1uf2A:undetectable | 2ygnA-1uf2A:10.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ul7 | MAP/MICROTUBULEAFFINITY-REGULATINGKINASE 3 (Mus musculus) |
PF02149(KA1) | 5 | LEU A 32ILE A 92ILE A 28MET A 64PHE A 79 | None | 1.13A | 2ygnA-1ul7A:undetectable | 2ygnA-1ul7A:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xdq | BACTERIAL SULFITEOXIDASE (Escherichiacoli) |
PF00174(Oxidored_molyb) | 5 | ILE A 212LEU A 214ILE A 72PHE A 135VAL A 197 | None | 1.12A | 2ygnA-1xdqA:undetectable | 2ygnA-1xdqA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a0u | INITIATION FACTOR 2B (Leishmaniamajor) |
PF01008(IF-2B) | 5 | LEU A 98ILE A 51LEU A 30ILE A 21VAL A 148 | None | 1.07A | 2ygnA-2a0uA:undetectable | 2ygnA-2a0uA:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bj0 | ACETYLCHOLINE-BINDING PROTEIN (Bulinustruncatus) |
PF02931(Neur_chan_LBD) | 5 | ILE A 137LEU A 33ILE A 196ILE A 36PHE A 120 | None | 1.14A | 2ygnA-2bj0A:undetectable | 2ygnA-2bj0A:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bp5 | CLATHRIN COATASSEMBLY PROTEINAP50 (Rattusnorvegicus) |
PF00928(Adap_comp_sub) | 6 | LEU M 206ILE M 263ILE M 243MET M 216PHE M 214VAL M 177 | None | 1.46A | 2ygnA-2bp5M:undetectable | 2ygnA-2bp5M:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dt8 | DEGV FAMILY PROTEIN (Thermusthermophilus) |
PF02645(DegV) | 5 | LEU A 28ILE A 88PHE A 69VAL A 112VAL A 110 | None | 0.93A | 2ygnA-2dt8A:undetectable | 2ygnA-2dt8A:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g02 | NISIN BIOSYNTHESISPROTEIN NISC (Lactococcuslactis) |
PF05147(LANC_like) | 5 | ILE A 290LEU A 293ILE A 313ILE A 241VAL A 272 | None | 1.05A | 2ygnA-2g02A:undetectable | 2ygnA-2g02A:14.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g4r | MOLYBDOPTERINBIOSYNTHESIS MOGPROTEIN (Mycobacteriumtuberculosis) |
PF00994(MoCF_biosynth) | 5 | ILE A 67LEU A 128ILE A 28ILE A 99VAL A 145 | None | 1.15A | 2ygnA-2g4rA:undetectable | 2ygnA-2g4rA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gnp | TRANSCRIPTIONALREGULATOR (Streptococcuspneumoniae) |
PF04198(Sugar-bind) | 5 | ILE A 113ILE A 205ILE A 128MET A 161PHE A 115 | None | 1.01A | 2ygnA-2gnpA:undetectable | 2ygnA-2gnpA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h0e | TRANSTHYRETIN-LIKEPROTEIN PUCM (Bacillussubtilis) |
PF00576(Transthyretin) | 5 | ILE A 29LEU A 54MET A 67PHE A 69VAL A 117 | None | 0.98A | 2ygnA-2h0eA:undetectable | 2ygnA-2h0eA:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hk0 | D-PSICOSE3-EPIMERASE (Agrobacteriumtumefaciens) |
PF01261(AP_endonuc_2) | 5 | LEU A 182ILE A 104LEU A 93ILE A 66VAL A 170 | LEU A 182 ( 0.6A)ILE A 104 ( 0.7A)LEU A 93 ( 0.6A)ILE A 66 ( 0.7A)VAL A 170 ( 0.6A) | 1.11A | 2ygnA-2hk0A:undetectable | 2ygnA-2hk0A:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hsm | GLUTAMYL-TRNASYNTHETASE,CYTOPLASMIC (Saccharomycescerevisiae) |
no annotation | 5 | LEU A 130ILE A 84ILE A 51PHE A 85VAL A 97 | None | 1.11A | 2ygnA-2hsmA:undetectable | 2ygnA-2hsmA:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j43 | SPYDX (Streptococcuspyogenes) |
PF03714(PUD) | 5 | ILE A 75LEU A 16MET A 47VAL A 61VAL A 33 | None | 1.14A | 2ygnA-2j43A:undetectable | 2ygnA-2j43A:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kii | PUTATIVEUNCHARACTERIZEDPROTEIN (Shewanellaoneidensis) |
PF07700(HNOB) | 5 | ILE A 176LEU A 130ILE A 159ILE A 98PHE A 91 | NoneNoneNoneHEM A 182 (-4.0A)None | 0.95A | 2ygnA-2kiiA:undetectable | 2ygnA-2kiiA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mdt | PUTATIVEUNCHARACTERIZEDPROTEIN (Sulfolobussolfataricus) |
no annotation | 5 | LEU A 97ILE A 5LEU A 13ILE A 84ILE A 40 | None | 1.06A | 2ygnA-2mdtA:undetectable | 2ygnA-2mdtA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oi2 | MEVALONATE KINASE (Streptococcuspneumoniae) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 5 | LEU A 258ILE A 14LEU A 31ILE A 263VAL A 22 | NoneNoneNoneNoneDP6 A 300 (-4.6A) | 1.14A | 2ygnA-2oi2A:undetectable | 2ygnA-2oi2A:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p88 | MANDELATERACEMASE/MUCONATELACTONIZING ENZYMEFAMILY PROTEIN (Bacillus cereus) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | LEU A 122ILE A 103LEU A 66ILE A 32VAL A 301 | None | 1.08A | 2ygnA-2p88A:undetectable | 2ygnA-2p88A:17.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r66 | GLYCOSYLTRANSFERASE, GROUP 1 (Halothermothrixorenii) |
PF00534(Glycos_transf_1)PF00862(Sucrose_synth) | 5 | LEU A 36ILE A 195ILE A 226ARG A 450ILE A 459 | None | 1.13A | 2ygnA-2r66A:undetectable | 2ygnA-2r66A:15.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y6v | PEROXISOMAL MEMBRANEPROTEIN LPX1 (Saccharomycescerevisiae) |
PF12697(Abhydrolase_6) | 5 | LEU A 324ILE A 142ILE A 166ILE A 86PHE A 57 | None | 1.05A | 2ygnA-2y6vA:undetectable | 2ygnA-2y6vA:18.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ygn | WNT INHIBITORYFACTOR 1 (Homo sapiens) |
PF02019(WIF) | 12 | LEU A 36ILE A 40LEU A 48ILE A 55MET A 63ARG A 76MET A 77ILE A 80MET A 87PHE A 89VAL A 152VAL A 154 | PCF A1179 ( 4.0A)NonePCF A1179 (-4.1A)PCF A1179 ( 4.5A)PCF A1179 ( 4.1A)MLY A 72 (-4.5A)PCF A1179 (-4.0A)NonePCF A1179 (-3.6A)PCF A1179 ( 3.8A)PCF A1179 (-4.4A)PCF A1179 ( 4.7A) | 0.00A | 2ygnA-2ygnA:29.7 | 2ygnA-2ygnA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ygo | WNT INHIBITORYFACTOR 1 (Homo sapiens) |
PF02019(WIF) | 8 | ILE A 40ILE A 55ARG A 76MET A 77ILE A 80MET A 87PHE A 89VAL A 152 | NonePCF A1213 (-4.0A)PCF A1213 (-3.6A)PCF A1213 (-3.5A)NonePCF A1213 ( 3.8A)PCF A1213 (-4.1A)PCF A1213 ( 4.7A) | 1.08A | 2ygnA-2ygoA:28.2 | 2ygnA-2ygoA:82.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ygo | WNT INHIBITORYFACTOR 1 (Homo sapiens) |
PF02019(WIF) | 11 | LEU A 36ILE A 40LEU A 48ILE A 55MET A 63MET A 77ILE A 80MET A 87PHE A 89VAL A 152VAL A 154 | PCF A1213 ( 4.2A)NonePCF A1213 (-4.3A)PCF A1213 (-4.0A)PCF A1213 ( 4.2A)PCF A1213 (-3.5A)NonePCF A1213 ( 3.8A)PCF A1213 (-4.1A)PCF A1213 ( 4.7A)PCF A1213 ( 4.7A) | 0.13A | 2ygnA-2ygoA:28.2 | 2ygnA-2ygoA:82.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ygq | WNT INHIBITORYFACTOR 1 (Homo sapiens) |
PF02019(WIF)PF12661(hEGF) | 10 | LEU A 36ILE A 40ILE A 55MET A 63MET A 77ILE A 80MET A 87PHE A 89VAL A 152VAL A 154 | NoneNonePCF A1275 ( 4.4A)PCF A1275 ( 4.1A)PCF A1275 (-3.2A)PCF A1275 (-4.7A)PCF A1275 (-3.2A)PCF A1275 (-4.6A)PCF A1275 (-3.6A)PCF A1275 (-4.9A) | 0.42A | 2ygnA-2ygqA:26.1 | 2ygnA-2ygqA:48.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ygq | WNT INHIBITORYFACTOR 1 (Homo sapiens) |
PF02019(WIF)PF12661(hEGF) | 10 | LEU A 36ILE A 40LEU A 48ILE A 55MET A 63MET A 77MET A 87PHE A 89VAL A 152VAL A 154 | NoneNonePCF A1275 (-4.6A)PCF A1275 ( 4.4A)PCF A1275 ( 4.1A)PCF A1275 (-3.2A)PCF A1275 (-3.2A)PCF A1275 (-4.6A)PCF A1275 (-3.6A)PCF A1275 (-4.9A) | 0.69A | 2ygnA-2ygqA:26.1 | 2ygnA-2ygqA:48.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ygq | WNT INHIBITORYFACTOR 1 (Homo sapiens) |
PF02019(WIF)PF12661(hEGF) | 6 | LEU A 165ILE A 40ILE A 55ILE A 80MET A 87PHE A 89 | NoneNonePCF A1275 ( 4.4A)PCF A1275 (-4.7A)PCF A1275 (-3.2A)PCF A1275 (-4.6A) | 1.38A | 2ygnA-2ygqA:26.1 | 2ygnA-2ygqA:48.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ygq | WNT INHIBITORYFACTOR 1 (Homo sapiens) |
PF02019(WIF)PF12661(hEGF) | 6 | LEU A 165ILE A 40ILE A 55ILE A 84MET A 87PHE A 89 | NoneNonePCF A1275 ( 4.4A)NonePCF A1275 (-3.2A)PCF A1275 (-4.6A) | 1.33A | 2ygnA-2ygqA:26.1 | 2ygnA-2ygqA:48.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zu8 | MANNOSYL-3-PHOSPHOGLYCERATE SYNTHASE (Pyrococcushorikoshii) |
PF09488(Osmo_MPGsynth) | 5 | LEU A 66ILE A 112LEU A 394VAL A 181VAL A 177 | None | 1.14A | 2ygnA-2zu8A:undetectable | 2ygnA-2zu8A:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a31 | PROBABLETHREONYL-TRNASYNTHETASE 1 (Aeropyrumpernix) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon) | 5 | LEU A 187LEU A 325ILE A 18MET A 332VAL A 58 | None | 1.02A | 2ygnA-3a31A:undetectable | 2ygnA-3a31A:14.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a45 | FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE (Acanthamoebapolyphagamimivirus) |
PF01149(Fapy_DNA_glyco)PF06831(H2TH) | 5 | ILE A 206LEU A 202ILE A 179ILE A 150PHE A 139 | None | 1.09A | 2ygnA-3a45A:undetectable | 2ygnA-3a45A:16.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3btz | ALPHA-KETOGLUTARATE-DEPENDENTDIOXYGENASE ALKBHOMOLOG 2 (Homo sapiens) |
PF13532(2OG-FeII_Oxy_2) | 5 | LEU A 178ILE A 158LEU A 85ILE A 81VAL A 145 | None | 1.15A | 2ygnA-3btzA:1.3 | 2ygnA-3btzA:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eb8 | CYSTEINEPROTEASE-LIKE VIRA (Shigellaflexneri) |
PF06872(EspG) | 5 | LEU A 374ILE A 186ILE A 216VAL A 344VAL A 369 | None | 1.06A | 2ygnA-3eb8A:undetectable | 2ygnA-3eb8A:18.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ee1 | EFFECTOR PROTEINVIRA (Shigellaflexneri) |
PF06872(EspG) | 5 | LEU A 374ILE A 186ILE A 216VAL A 344VAL A 369 | None | 0.95A | 2ygnA-3ee1A:undetectable | 2ygnA-3ee1A:16.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ez1 | AMINOTRANSFERASEMOCR FAMILY (Deinococcusgeothermalis) |
PF12897(Aminotran_MocR) | 5 | LEU A 143ILE A 175ILE A 127MET A 152ILE A 189 | None | 1.11A | 2ygnA-3ez1A:undetectable | 2ygnA-3ez1A:15.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fdb | PUTATIVEPLP-DEPENDENTBETA-CYSTATHIONASE (Corynebacteriumdiphtheriae) |
PF00155(Aminotran_1_2) | 5 | ILE A 313LEU A 352ILE A 302PHE A 315VAL A 372 | None | 1.15A | 2ygnA-3fdbA:undetectable | 2ygnA-3fdbA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3flt | SAP-LIKE PENTRAXIN (Limuluspolyphemus) |
PF00354(Pentaxin) | 5 | ILE A 194ILE A 4PHE A 201VAL A 209VAL A 207 | None | 1.10A | 2ygnA-3fltA:undetectable | 2ygnA-3fltA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gfo | COBALT IMPORTATP-BINDING PROTEINCBIO 1 (Clostridiumperfringens) |
PF00005(ABC_tran) | 5 | LEU A 207LEU A 48ILE A 196ILE A 25VAL A 229 | None | 1.12A | 2ygnA-3gfoA:undetectable | 2ygnA-3gfoA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l6a | EUKARYOTICTRANSLATIONINITIATION FACTOR 4GAMMA 2 (Homo sapiens) |
PF02020(W2)PF02847(MA3) | 5 | LEU A 69LEU A 124ILE A 114PHE A 81VAL A 48 | None | 1.04A | 2ygnA-3l6aA:undetectable | 2ygnA-3l6aA:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lov | PROTOPORPHYRINOGENOXIDASE (Exiguobacteriumsibiricum) |
PF01593(Amino_oxidase) | 5 | ILE A 284LEU A 256ILE A 259VAL A 427VAL A 423 | FAD A 500 (-3.7A)FAD A 500 (-4.9A)NoneNoneNone | 1.12A | 2ygnA-3lovA:undetectable | 2ygnA-3lovA:15.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m19 | VARIABLE LYMPHOCYTERECEPTOR A DIVERSITYREGION (Petromyzonmarinus) |
PF13855(LRR_8) | 5 | LEU A 63LEU A 161ILE A 145VAL A 125VAL A 101 | None | 1.10A | 2ygnA-3m19A:undetectable | 2ygnA-3m19A:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m19 | VARIABLE LYMPHOCYTERECEPTOR A DIVERSITYREGION (Petromyzonmarinus) |
PF13855(LRR_8) | 5 | LEU A 65LEU A 161ILE A 145VAL A 125VAL A 101 | None | 1.00A | 2ygnA-3m19A:undetectable | 2ygnA-3m19A:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mdq | EXOPOLYPHOSPHATASE (Cytophagahutchinsonii) |
PF02541(Ppx-GppA) | 5 | LEU A 206ILE A 198ILE A 279MET A 135PHE A 144 | None | 1.10A | 2ygnA-3mdqA:undetectable | 2ygnA-3mdqA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n2q | SEX PHEROMONESTAPH-CAM373 (Bacillus cereus) |
PF07537(CamS) | 5 | ILE A 252LEU A 294ILE A 261PHE A 248VAL A 312 | None | 1.07A | 2ygnA-3n2qA:undetectable | 2ygnA-3n2qA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oce | FUMARATE LYASE:DELTACRYSTALLIN (Brucellaabortus) |
PF00206(Lyase_1)PF10415(FumaraseC_C) | 5 | ILE A 390LEU A 294ILE A 308ARG A 185ILE A 290 | None | 1.06A | 2ygnA-3oceA:undetectable | 2ygnA-3oceA:14.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ojl | CAP5O (Staphylococcusaureus) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | ILE A 78LEU A 101MET A 125ILE A 133VAL A 183 | None | 1.06A | 2ygnA-3ojlA:undetectable | 2ygnA-3ojlA:16.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wo9 | VARIABLE LYMPHOCYTERECEPTOR C (Lethenteroncamtschaticum) |
PF01462(LRRNT)PF13855(LRR_8) | 5 | LEU A 73LEU A 169ILE A 153VAL A 133VAL A 109 | None | 1.09A | 2ygnA-3wo9A:undetectable | 2ygnA-3wo9A:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4afr | METACASPASE (Trypanosomabrucei) |
PF00656(Peptidase_C14) | 5 | LEU A 100ILE A 255LEU A 322ILE A 328MET A 253 | None | 0.97A | 2ygnA-4afrA:undetectable | 2ygnA-4afrA:16.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ao7 | ESTERASE (unidentified) |
PF12146(Hydrolase_4) | 5 | LEU A 192LEU A 126ILE A 160ILE A 129VAL A 65 | None | 1.10A | 2ygnA-4ao7A:undetectable | 2ygnA-4ao7A:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4blp | PACKAGING ENZYME P4 (Pseudomonasphage phi13) |
PF11602(NTPase_P4) | 5 | ILE A 212LEU A 253ILE A 172PHE A 215VAL A 70 | None | 1.13A | 2ygnA-4blpA:undetectable | 2ygnA-4blpA:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dy0 | GLIA-DERIVED NEXIN (Homo sapiens) |
PF00079(Serpin) | 5 | ILE A 236LEU A 274ILE A 223MET A 262VAL A 370 | None | 1.06A | 2ygnA-4dy0A:undetectable | 2ygnA-4dy0A:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4emy | AMINOTRANSFERASECLASS I AND II (Anaerococcusprevotii) |
PF00155(Aminotran_1_2) | 5 | ILE A 375LEU A 403ILE A 37ARG A 332ILE A 358 | None | 1.12A | 2ygnA-4emyA:undetectable | 2ygnA-4emyA:16.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h2k | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Haemophilusinfluenzae) |
PF01546(Peptidase_M20) | 5 | ILE A 29LEU A 12ILE A 109MET A 101VAL A 145 | NoneNoneNone ZN A1001 ( 4.4A)None | 1.10A | 2ygnA-4h2kA:undetectable | 2ygnA-4h2kA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jo0 | CMLA (Streptomycesvenezuelae) |
PF12706(Lactamase_B_2) | 5 | LEU A 458ILE A 303LEU A 301ILE A 319VAL A 492 | None | 1.02A | 2ygnA-4jo0A:undetectable | 2ygnA-4jo0A:15.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kjd | INTESTINAL-TYPEALKALINE PHOSPHATASE1 (Rattusnorvegicus) |
PF00245(Alk_phosphatase) | 5 | LEU A 328LEU A 38ARG A 442ILE A 458VAL A 437 | None | 0.90A | 2ygnA-4kjdA:undetectable | 2ygnA-4kjdA:16.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m7e | PROTEINBRASSINOSTEROIDINSENSITIVE 1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF12799(LRR_4)PF13516(LRR_6)PF13855(LRR_8) | 6 | ILE A 674LEU A 683ILE A 670MET A 661MET A 677PHE A 581 | None | 1.20A | 2ygnA-4m7eA:undetectable | 2ygnA-4m7eA:10.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mf6 | GLUTATHIONES-TRANSFERASE DOMAIN (Paraburkholderiagraminis) |
PF00043(GST_C)PF02798(GST_N) | 5 | LEU A 161ILE A 126ILE A 205VAL A 219VAL A 224 | None | 1.08A | 2ygnA-4mf6A:undetectable | 2ygnA-4mf6A:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mki | ENERGY-COUPLINGFACTOR TRANSPORTERATP-BINDING PROTEINECFA2 (Caldanaerobactersubterraneus) |
no annotation | 5 | LEU B 267ILE B 38LEU B 49ILE B 26MET B 217 | None | 1.15A | 2ygnA-4mkiB:undetectable | 2ygnA-4mkiB:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mps | BETA-GALACTOSIDEALPHA-2,6-SIALYLTRANSFERASE 1 (Rattusnorvegicus) |
PF00777(Glyco_transf_29) | 5 | LEU A 395MET A 375ILE A 325MET A 329PHE A 398 | None | 0.93A | 2ygnA-4mpsA:undetectable | 2ygnA-4mpsA:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q7l | UNCHARACTERIZED ABCTRANSPORTERATP-BINDING PROTEINTM_0288 (Thermotogamaritima) |
PF00005(ABC_tran) | 5 | ILE A 412ILE A 419ARG A 428ILE A 544PHE A 357 | None | 1.11A | 2ygnA-4q7lA:undetectable | 2ygnA-4q7lA:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q7l | UNCHARACTERIZED ABCTRANSPORTERATP-BINDING PROTEINTM_0288 (Thermotogamaritima) |
PF00005(ABC_tran) | 5 | ILE A 412ILE A 419ARG A 428ILE A 544VAL A 370 | None | 1.15A | 2ygnA-4q7lA:undetectable | 2ygnA-4q7lA:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qdg | PUTATIVE ADHESIN (Bacteroidesthetaiotaomicron) |
PF08842(Mfa2) | 5 | LEU A 284ILE A 181MET A 309PHE A 311VAL A 266 | None | 1.12A | 2ygnA-4qdgA:undetectable | 2ygnA-4qdgA:17.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r6f | LEUCINE RICH REPEATDLRR_I (syntheticconstruct) |
PF12354(Internalin_N)PF13855(LRR_8) | 5 | LEU A 67LEU A 163ILE A 147VAL A 127VAL A 103 | None | 1.14A | 2ygnA-4r6fA:undetectable | 2ygnA-4r6fA:16.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r9n | LMO0547 PROTEIN (Listeriamonocytogenes) |
PF04198(Sugar-bind) | 5 | LEU A 68ARG A 305MET A 306ILE A 300VAL A 238 | None | 1.13A | 2ygnA-4r9nA:undetectable | 2ygnA-4r9nA:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rns | PCP DEGRADATIONTRANSCRIPTIONALACTIVATION PROTEIN (Sphingobiumchlorophenolicum) |
PF03466(LysR_substrate) | 5 | ILE A 101LEU A 115ILE A 299MET A 111VAL A 275 | None | 1.06A | 2ygnA-4rnsA:undetectable | 2ygnA-4rnsA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s1w | GLUTAMINE--FRUCTOSE-6-PHOSPHATEAMINOTRANSFERASE[ISOMERIZING] (Staphylococcusaureus) |
PF01380(SIS) | 5 | ILE A 371LEU A 389ILE A 345ILE A 267VAL A 417 | None | 1.11A | 2ygnA-4s1wA:undetectable | 2ygnA-4s1wA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ud4 | POLY(A) RNAPOLYMERASE PROTEINCID1 (Schizosaccharomycespombe) |
PF01909(NTP_transf_2)PF03828(PAP_assoc) | 5 | ILE A 328LEU A 326ILE A 350VAL A 192VAL A 189 | None | 1.04A | 2ygnA-4ud4A:undetectable | 2ygnA-4ud4A:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uir | OLEATE HYDRATASE (Elizabethkingiameningoseptica) |
PF06100(MCRA) | 5 | ILE A 67ILE A 327ILE A 82PHE A 94VAL A 270 | None | 1.06A | 2ygnA-4uirA:undetectable | 2ygnA-4uirA:12.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yis | MEGANUCLEASE I-CPAMI (Cryphonectriaparasitica) |
PF00961(LAGLIDADG_1) | 5 | LEU A 105ILE A 86LEU A 60ILE A 56PHE A 41 | None | 0.98A | 2ygnA-4yisA:undetectable | 2ygnA-4yisA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yw5 | NEURAMINIDASE C (Streptococcuspneumoniae) |
PF02012(BNR)PF02973(Sialidase)PF13088(BNR_2) | 5 | LEU A 170ILE A 134LEU A 105ILE A 221PHE A 132 | None | 1.10A | 2ygnA-4yw5A:undetectable | 2ygnA-4yw5A:13.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z7y | DIPHOSPHOMEVALONATEDECARBOXYLASE (Sulfolobussolfataricus) |
PF00288(GHMP_kinases_N) | 5 | LEU A 305ILE A 182LEU A 39ILE A 311ILE A 37 | None | 1.11A | 2ygnA-4z7yA:undetectable | 2ygnA-4z7yA:17.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5by3 | BTGH115A (Bacteroidesthetaiotaomicron) |
PF15979(Glyco_hydro_115) | 6 | LEU A 202MET A 364ILE A 373MET A 418PHE A 447VAL A 434 | None | 1.26A | 2ygnA-5by3A:undetectable | 2ygnA-5by3A:10.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d55 | HDAB,HDAA (ADHESIN),HUS-ASSOCIATEDDIFFUSE ADHERENCE (Escherichiacoli) |
PF05775(AfaD) | 5 | LEU A 130ILE A 3LEU A 5ILE A 96VAL A 83 | None | 1.09A | 2ygnA-5d55A:undetectable | 2ygnA-5d55A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e31 | PENICILLIN BINDINGPROTEIN 2 PRIME (Enterococcusfaecium) |
PF00905(Transpeptidase)PF03717(PBP_dimer)PF05223(MecA_N) | 5 | LEU A 568ILE A 505ILE A 427VAL A 650VAL A 367 | None | 1.03A | 2ygnA-5e31A:undetectable | 2ygnA-5e31A:11.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e5b | FACT COMPLEX SUBUNITSPT16 (Homo sapiens) |
PF00557(Peptidase_M24)PF14826(FACT-Spt16_Nlob) | 5 | ILE A 247LEU A 217ILE A 205MET A 266VAL A 292 | None | 0.96A | 2ygnA-5e5bA:undetectable | 2ygnA-5e5bA:16.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e8c | UL31 (Suidalphaherpesvirus1) |
PF02718(Herpes_UL31) | 5 | LEU A 65LEU A 115ILE A 118VAL A 164VAL A 180 | None | 1.13A | 2ygnA-5e8cA:undetectable | 2ygnA-5e8cA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5im3 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (Pseudomonasaeruginosa) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF03477(ATP-cone) | 5 | LEU A 459ILE A 487MET A 492PHE A 491VAL A 542 | None | 1.04A | 2ygnA-5im3A:undetectable | 2ygnA-5im3A:9.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ksd | ATPASE 2, PLASMAMEMBRANE-TYPE (Arabidopsisthaliana) |
PF00122(E1-E2_ATPase)PF00690(Cation_ATPase_N)PF00702(Hydrolase) | 5 | ILE A 287LEU A 103ILE A 99MET A 73VAL A 657 | None | 1.08A | 2ygnA-5ksdA:undetectable | 2ygnA-5ksdA:12.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lbh | CAIP (Helicobactercinaedi) |
PF00210(Ferritin) | 5 | ILE A 77ILE A 42PHE A 101VAL A 49VAL A 53 | None | 1.15A | 2ygnA-5lbhA:undetectable | 2ygnA-5lbhA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m6p | TYROCIDINE SYNTHASE2 (Brevibacillusparabrevis) |
no annotation | 5 | LEU A3511LEU A3550ILE A3525ILE A3553VAL A3389 | None | 1.10A | 2ygnA-5m6pA:undetectable | 2ygnA-5m6pA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nbo | GLYCOSYL HYDROLASEFAMILY 16 (Bacteroidesovatus) |
no annotation | 5 | ILE A 265LEU A 84ILE A 115PHE A 41VAL A 48 | None | 1.10A | 2ygnA-5nboA:undetectable | 2ygnA-5nboA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wk4 | VARIABLE LYMPHOCYTERECEPTOR 39 (Petromyzonmarinus) |
no annotation | 5 | LEU D 54LEU D 152ILE D 136VAL D 116VAL D 92 | None | 1.12A | 2ygnA-5wk4D:undetectable | 2ygnA-5wk4D:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wk4 | VARIABLE LYMPHOCYTERECEPTOR 39 (Petromyzonmarinus) |
no annotation | 5 | LEU D 56LEU D 152ILE D 136VAL D 116VAL D 92 | None | 1.03A | 2ygnA-5wk4D:undetectable | 2ygnA-5wk4D:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wrk | AP-2 COMPLEX SUBUNITMU (Rattusnorvegicus) |
no annotation | 5 | ILE A 263ILE A 220MET A 216PHE A 214VAL A 177 | None | 1.08A | 2ygnA-5wrkA:2.0 | 2ygnA-5wrkA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wrl | AP-2 COMPLEX SUBUNITMU (Rattusnorvegicus) |
no annotation | 6 | LEU A 206ILE A 263ILE A 243MET A 216PHE A 214VAL A 177 | None | 1.33A | 2ygnA-5wrlA:undetectable | 2ygnA-5wrlA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b9u | DNA GYRASE, SUBUNITB:SHORT-CHAINDEHYDROGENASE/REDUCTASESDR:GLUCOSE/RIBITOLDEHYDROGENASE (Brucellaabortus) |
no annotation | 5 | LEU A 4MET A 22ILE A 83VAL A 183VAL A 243 | None | 1.12A | 2ygnA-6b9uA:undetectable | 2ygnA-6b9uA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bog | RNAPOLYMERASE-ASSOCIATED PROTEIN RAPA (Escherichiacoli) |
no annotation | 5 | ILE A 726LEU A 722ARG A 129ILE A 784PHE A 751 | None | 0.96A | 2ygnA-6bogA:undetectable | 2ygnA-6bogA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bxa | VARIABLE LYMPHOCYTERECEPTOR 2 (Petromyzonmarinus) |
no annotation | 5 | LEU C 54LEU C 152ILE C 136VAL C 116VAL C 92 | None | 1.05A | 2ygnA-6bxaC:undetectable | 2ygnA-6bxaC:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ckb | - (-) |
no annotation | 5 | LEU A 187ILE A 219ILE A 132MET A 184VAL A 197 | None | 0.92A | 2ygnA-6ckbA:undetectable | 2ygnA-6ckbA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6egx | STRUCTURAL PROTEINVP2 (Sacbrood virus) |
no annotation | 5 | ILE B 64ILE B 169MET B 114PHE B 116VAL B 128 | None | 1.13A | 2ygnA-6egxB:undetectable | 2ygnA-6egxB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ejj | WLAC PROTEIN (Campylobacterjejuni) |
no annotation | 5 | LEU A 165ILE A 114LEU A 113ILE A 92ILE A 103 | None | 1.14A | 2ygnA-6ejjA:undetectable | 2ygnA-6ejjA:undetectable |